Detailed information for compound 923573

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 381.45 | Formula: C20H24FN7
  • H donors: 2 H acceptors: 3 LogP: 3.23 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCN(CC1)c1ncc2c(c1)[nH]c(n2)Nc1cc(C2CC2)c(c(n1)C)F
  • InChi: 1S/C20H24FN7/c1-12-19(21)14(13-3-4-13)9-17(23-12)26-20-24-15-10-18(22-11-16(15)25-20)28-7-5-27(2)6-8-28/h9-11,13H,3-8H2,1-2H3,(H2,23,24,25,26)
  • InChiKey: YCNGNCARDVDXJO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens potassium voltage-gated channel, subfamily H (eag-related), member 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis voltage and ligand gated potassium channel, putative Get druggable targets OG5_128858 All targets in OG5_128858
Echinococcus multilocularis potassium voltage gated channel subfamily H Get druggable targets OG5_128858 All targets in OG5_128858
Trichomonas vaginalis voltage and ligand gated potassium channel, putative Get druggable targets OG5_128858 All targets in OG5_128858
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma japonicum ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma mansoni voltage-gated potassium channel Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma japonicum ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma japonicum Potassium voltage-gated channel subfamily H member 2, putative Get druggable targets OG5_128858 All targets in OG5_128858
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog Get druggable targets OG5_128858 All targets in OG5_128858
Loa Loa (eye worm) voltage and ligand gated potassium channel Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma mansoni voltage-gated potassium channel Get druggable targets OG5_128858 All targets in OG5_128858
Echinococcus granulosus potassium voltage gated channel subfamily H Get druggable targets OG5_128858 All targets in OG5_128858
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-like 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.000804072 0 0.5
Trypanosoma cruzi ULK family serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Associated kinase of Tb14-3-3, putative 0.000804072 0 0.5
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica casein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, STE STE20 0.000804072 0 0.5
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 9 0.000804072 0 0.5
Chlamydia trachomatis serine/threonine protein kinase 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Echinococcus multilocularis expressed conserved protein 0.0013067 0.00146499 0.00146499
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi casein kinase I, putative 0.000804072 0 0.5
Trypanosoma cruzi tousled-like kinase II, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/MAPK protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, STE STE20 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 9 0.000804072 0 0.5
Trypanosoma cruzi STE/STE7 protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica casein kinase, putative 0.000804072 0 0.5
Plasmodium vivax protein kinase Crk2 0.000804072 0 0.5
Trypanosoma cruzi Nuclear Dbf2-related kinase 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 8, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK14, putative 0.000804072 0 0.5
Plasmodium vivax protein kinase, putative 0.000804072 0 0.5
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.00354585 0.0079914 0.0079914
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CLK 0.000804072 0 0.5
Brugia malayi map kinase activated protein kinase protein 2 0.343895 1 1
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC family protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK22, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related protein kinase 11, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CK1 Casein kinase 0.000804072 0 0.5
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi tyrosine protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CK2 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 10, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Associated kinase of Tb14-3-3, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Mycobacterium ulcerans serine/threonine-protein kinase PknG 0.000804072 0 0.5
Trypanosoma cruzi NIMA-related kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, AGC AKT 0.000804072 0 0.5
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine-protein kinase a, putative 0.000804072 0 0.5
Leishmania major protein kinase, putative 0.0013067 0.00146499 1
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase kinase 1 0.000804072 0 0.5
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Plasmodium vivax protein kinase, putative 0.000804072 0 0.5
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.000804072 0 0.5
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.00354585 0.0079914 0.0079914
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi tousled-like kinase II, putative 0.000804072 0 0.5
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Cell division protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC RCK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Trypanosoma cruzi tyrosine protein kinase, putative 0.000804072 0 0.5
Chlamydia trachomatis serine/threonine-protein kinase 0.000804072 0 0.5
Trypanosoma cruzi casein kinase, putative 0.000804072 0 0.5
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.00325276 0.00713715 1
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Echinococcus granulosus MAP kinase activated protein kinase 2 0.343895 1 1
Echinococcus granulosus voltage gated potassium channel 0.00115922 0.00103514 0.00103514
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi CK1/TTBK protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi Pseudokinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC SRPK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine kinase, putative 0.000804072 0 0.5
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 3 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Mycobacterium tuberculosis Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E) 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, AGC NDR 0.000804072 0 0.5
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.000804072 0 0.5
Giardia lamblia Kinase, CDC7 0.000804072 0 0.5
Plasmodium vivax calcium-dependent protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Wee1-like protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax CDK-related protein kinase 6, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Trypanosoma cruzi casein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Mycobacterium ulcerans membrane-anchored serine/threonine-protein kinase 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK14, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica mitogen-activated protein kinase 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CDK 0.000804072 0 0.5
Entamoeba histolytica p21-activated kinase 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Echinococcus granulosus cGMP dependent protein kinase 1 0.0013067 0.00146499 0.00146499
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, STE Dicty2 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CDK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase-like protein, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Repressor of differentiation kinase 1, putative 0.000804072 0 0.5
Trypanosoma cruzi kinetoplastid kinetochore protein 2, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Plasmodium vivax protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase 5, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CAMK CAMKL 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase PK4, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi SNF1-related protein kinases, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC DYRK 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.00115922 0.00103514 0.00103514
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax casein kinase 1, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase with WD repeats 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax protein kinase domain containing protein 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi CMGC family protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Plasmodium vivax hypothetical protein, conserved 0.000804072 0 0.5
Mycobacterium ulcerans serine/threonine-protein kinase a PknA 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica PH domain containing protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Mycobacterium ulcerans serine/threonine-protein kinase transcriptional regulatory protein PknK_2 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax cyclin g-associated kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase-like protein, putative 0.000804072 0 0.5
Mycobacterium ulcerans transmembrane serine/threonine-protein kinase PknQ 0.000804072 0 0.5
Schistosoma mansoni serine/threonine protein kinase 0.343895 1 1
Trypanosoma cruzi zinc finger protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC MAPK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi NAK family pseudokinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-GL-like 0.000804072 0 0.5
Plasmodium vivax hypothetical protein, conserved 0.000804072 0 0.5
Giardia lamblia Kinase, STE STE20 0.000804072 0 0.5
Schistosoma mansoni voltage-gated potassium channel 0.00390936 0.00905092 0.00905092
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi map kinase, putative 0.000804072 0 0.5
Plasmodium vivax protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC family protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase I, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK15, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.000804072 0 0.5
Echinococcus granulosus c-Jun N-terminal kinases 0.0207793 0.0582213 0.0582213
Trypanosoma cruzi MAPK/MAK/MRK overlapping kinase, putative 0.000804072 0 0.5
Onchocerca volvulus Serine\/threonine kinase homolog 0.000804072 0 0.5
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.00115922 0.00103514 0.00103514
Mycobacterium ulcerans serine/threonine-protein kinase transcriptional regulatory protein PknK_3 0.000804072 0 0.5
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.00325276 0.00713715 1
Plasmodium vivax protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, TTK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi ULK family pseudokinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK19, putative 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Wee1-like protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Mitogen-activated protein kinase 6 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica cell division protein kinase 2, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Plasmodium vivax protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK6, putative 0.000804072 0 0.5
Entamoeba histolytica cell division protein kinase 2, putative 0.000804072 0 0.5
Schistosoma mansoni voltage-gated potassium channel 0.00115922 0.00103514 0.00103514
Trypanosoma cruzi CMGC/CLK family protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica casein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Mycobacterium ulcerans serine/threonine-protein kinase B PknB 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica PH domain containing protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica casein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, Nek-like 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi NIMA-related kinase, putative 0.000804072 0 0.5
Plasmodium vivax hypothetical protein, conserved 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi rac serine-threonine kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi STE20-like serine/threonine-protein kinase 2, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related protein kinase 11, putative 0.000804072 0 0.5
Giardia lamblia Kinase, STE STE20 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK15, putative 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Plasmodium vivax serine/threonine-protein kinase 2, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CDKL 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein, conserved 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi ULK family serine/threonine-protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus Serine\/threonine kinase homolog 0.000804072 0 0.5
Trypanosoma cruzi CAMK/CAMKL pseudokinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/RCK protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/CLK family protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE20-like serine/threonine-protein kinase 2, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.000804072 0 0.5
Schistosoma mansoni voltage-gated potassium channel 0.00115922 0.00103514 0.00103514
Giardia lamblia Kinase, Uni1 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi CAMK/CAMKL pseudokinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.343895 1 1
Giardia lamblia Kinase 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CDK 0.000804072 0 0.5
Trypanosoma cruzi Aurora kinase 3, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0207793 0.0582213 0.0582213
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0207793 0.0582213 0.0582213
Trypanosoma cruzi protein kinase-like protein, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase I, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/CLK family protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase 1, putative 0.000804072 0 0.5
Trypanosoma cruzi hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.000804072 0 0.5
Mycobacterium ulcerans serine/threonine-protein kinase PknF_2 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK10, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase II, alpha chain, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi Aurora kinase 2, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK6, putative 0.000804072 0 0.5
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.00116759 0.00105952 1
Plasmodium vivax serine/threonine protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Mycobacterium ulcerans anchored-membrane serine/threonine-protein kinase PknF 0.000804072 0 0.5
Plasmodium falciparum cGMP-dependent protein kinase 0.0013067 0.00146499 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-like 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK6, putative 0.000804072 0 0.5
Giardia lamblia Kinase, ULK 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Trypanosoma cruzi CMGC/CLK family protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC DYRK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica PH domain containing protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 12 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax unspecified product 0.000804072 0 0.5
Echinococcus granulosus cGMP dependent protein kinase 0.0013067 0.00146499 0.00146499
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi polo-like protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi glycogen synthase kinase-3 alpha, putative 0.000804072 0 0.5
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine-protein kinase, putative 0.000804072 0 0.5
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0013067 0.00146499 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.00354585 0.0079914 0.0079914
Trypanosoma cruzi hypothetical protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CAMK CAMKL 0.000804072 0 0.5
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine-protein kinase NAK, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK6, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica Rab GTPase activating protein, putative 0.000804072 0 0.5
Giardia lamblia Kinase, STE Dicty2 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Trypanosoma cruzi CMGC/RCK protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi NIMA-related kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi Protein kinase domain, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/MAPK protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC RCK 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC DYRK 0.000804072 0 0.5
Trypanosoma cruzi STE/STE7 protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica PH domain containing protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Brugia malayi Egg laying defective protein 4 0.0013067 0.00146499 0.00146499
Trypanosoma cruzi cdc2-related kinase 2, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase kinase kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein lipid droplet kinase (LDK) 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CMGC-GL1 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Plasmodium vivax serine/threonine-protein kinase PRP4K, putative 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus Asator homolog 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.000804072 0 0.5
Entamoeba histolytica PH domain containing protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, VPS15 0.000804072 0 0.5
Echinococcus multilocularis voltage gated potassium channel 0.00115922 0.00103514 0.00103514
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica predicted protein 0.000804072 0 0.5
Mycobacterium ulcerans Ser/Thr protein kinase 0.000804072 0 0.5
Trypanosoma cruzi 3-phosphoinositide-dependent protein kinase 1, putative 0.000804072 0 0.5
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.000804072 0 0.5
Chlamydia trachomatis serine/threonine protein kinase 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0013067 0.00146499 0.00146499
Loa Loa (eye worm) AGC/PKG protein kinase 0.0013067 0.00146499 0.00146499
Plasmodium vivax serine/threonine protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Giardia lamblia Kinase, CAMKK 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CMGC-GL1 0.000804072 0 0.5
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi casein kinase, delta isoform, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi glycogen synthase kinase-3 alpha, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi p21-activated kinase 3, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.000804072 0 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0013067 0.00146499 0.00146499
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi kinetoplastid kinetochore protein 3, putative 0.000804072 0 0.5
Trypanosoma cruzi AGC essential kinase 1 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Mycobacterium tuberculosis Serine/threonine-protein kinase transcriptional regulatory protein PknK (protein kinase K) (STPK K) 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax serine/threonine-specific protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Mycobacterium leprae PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE L PKNL (PROTEIN KINASE L) (STPK L) 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica PH domain containing protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.000804072 0 0.5
Mycobacterium tuberculosis Serine/threonine-protein kinase PknG (protein kinase G) (STPK G) 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica casein kinase II alpha subunit, putative 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Plasmodium vivax serine/threonine kinase-1, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Loa Loa (eye worm) hypothetical protein 0.00304322 0.00652641 0.00652641
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0013067 0.00146499 0.00146499
Plasmodium vivax calcium-dependent protein kinase 6, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.000804072 0 0.5
Entamoeba histolytica cell division protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Small Surface Antigen 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CAMK CAMKL 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0013067 0.00146499 0.00146499
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi rac serine-threonine kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, CAMK unique 0.000804072 0 0.5
Mycobacterium ulcerans Ser/Thr protein kinase 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica casein kinase 1, putative 0.000804072 0 0.5
Trypanosoma cruzi Repressor of differentiation kinase 1, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase 9, putative 0.000804072 0 0.5
Trypanosoma cruzi Wee1-like protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.000804072 0 0.5
Mycobacterium tuberculosis Probable transmembrane serine/threonine-protein kinase I PknI (protein kinase I) (STPK I) (phosphorylase B kinase kinase) (hydro 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related protein kinase 4, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi AGC/RSK family serine/threonine kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Plasmodium vivax protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi AGC family serine/threonine kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, PEK 0.000804072 0 0.5
Trypanosoma cruzi casein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi kinase, putative 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase PK4, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC GSK 0.000804072 0 0.5
Entamoeba histolytica serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 1 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Long-flagella protein, kinase, CMGC RCK 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Plasmodium vivax calcium-dependent protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase 6, putative 0.000804072 0 0.5
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase VPS15, putative 0.000804072 0 0.5
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 3, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.343895 1 1
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Entamoeba histolytica SH2-protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi casein kinase II, alpha chain, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, Wnk 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus Kinase homolog 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Onchocerca volvulus Dual specificity protein kinase TTK homolog 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi hypothetical protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related protein kinase 7, putative 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Echinococcus granulosus potassium voltage gated channel subfamily H 0.00115922 0.00103514 0.00103514
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/MAPK protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Mycobacterium ulcerans Ser/Thr protein kinase 0.000804072 0 0.5
Echinococcus granulosus potassium voltage gated channel subfamily H 0.00354585 0.0079914 0.0079914
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0013067 0.00146499 0.00146499
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/SRPK protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax cdc2-like protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, STE STE20 0.000804072 0 0.5
Mycobacterium ulcerans Ser/Thr protein kinase 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CDK 0.000804072 0 0.5
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.000804072 0 0.5
Entamoeba histolytica serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CDK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica receptor protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 8, putative 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 2, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Plasmodium vivax protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC MAPK 0.000804072 0 0.5
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.000804072 0 0.5
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, AGC PKA 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi polo-like protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Entamoeba histolytica protein kinase 2, putative 0.000804072 0 0.5
Trypanosoma cruzi MEKK-related kinase 1, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase kinase 4, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica cell division protein kinase 2, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK20, putative 0.000804072 0 0.5
Trypanosoma cruzi Protein kinase B, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Loa Loa (eye worm) hypothetical protein 0.00115922 0.00103514 0.00103514
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Pseudokinase, putative 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi CMGC/CLK family protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi kinatase, putative 0.000804072 0 0.5
Entamoeba histolytica ankyrin repeat protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica serine/threonine- protein kinase DCAMKL3, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica HEAT repeat domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi kinatase, putative 0.000804072 0 0.5
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica cell division protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NAK 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase 9, putative 0.000804072 0 0.5
Schistosoma mansoni voltage-gated potassium channel 0.00390936 0.00905092 0.00905092
Trypanosoma cruzi polo-like protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Plasmodium vivax eukaryotic translation initiation factor 2-alpha kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK22, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Pseudokinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Plasmodium vivax mitogen-activated protein kinase 1, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Plasmodium vivax 3-phosphoinositide dependent protein kinase-1, putative 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related protein kinase 4, putative 0.000804072 0 0.5
Entamoeba histolytica serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Mycobacterium tuberculosis Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H) 0.000804072 0 0.5
Trypanosoma cruzi CMGC/CLK family protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.000804072 0 0.5
Entamoeba histolytica serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 3, putative 0.000804072 0 0.5
Entamoeba histolytica serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Plasmodium vivax protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK20, putative 0.000804072 0 0.5
Giardia lamblia Kinase, PLK 0.000804072 0 0.5
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK14, putative 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 3 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi aurora B kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-like 0.000804072 0 0.5
Giardia lamblia Kinase, NAK 0.000804072 0 0.5
Entamoeba histolytica PH domain containing protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 1 0.000804072 0 0.5
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, STE STE20 0.000804072 0 0.5
Echinococcus granulosus calcium activated potassium channel 0.00109716 0.000854243 0.000854243
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase II, putative 0.000804072 0 0.5
Trypanosoma cruzi Mitogen-activated protein kinase 6 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC GSK 0.000804072 0 0.5
Brugia malayi Stress-activated protein kinase jnk-1 0.0207793 0.0582213 0.0582213
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Protein kinase B, putative 0.000804072 0 0.5
Plasmodium vivax protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax tyrosine kinase-like protein, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Leishmania major protein kinase, putative 0.0013067 0.00146499 1
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, Wee 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi casein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC CDK 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase I, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.000804072 0 0.5
Entamoeba histolytica casein kinase I isoform delta, putative 0.000804072 0 0.5
Giardia lamblia Kinase, AGC MAST 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-frag 0.000804072 0 0.5
Entamoeba histolytica serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica tyrosine kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.000804072 0 0.5
Trypanosoma cruzi hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.000804072 0 0.5
Trypanosoma cruzi CMGC/MAPK protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Aurora kinase 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase, putative 0.000804072 0 0.5
Mycobacterium tuberculosis Anchored-membrane serine/threonine-protein kinase PknF (protein kinase F) (STPK F) 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Protein kinase B 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.000804072 0 0.5
Trypanosoma cruzi Protein kinase domain, putative 0.000804072 0 0.5
Giardia lamblia Kinase, Nek-like 0.000804072 0 0.5
Entamoeba histolytica serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase , putative 0.000804072 0 0.5
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Plasmodium vivax cdc2-related protein kinase 1, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, CMGC DYRK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi casein kinase 1 isoform 2, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi Aurora kinase 3, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Pseudokinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Echinococcus multilocularis calcium activated potassium channel 0.00109716 0.000854243 0.000854243
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine-protein kinase NAK, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK7, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK14, putative 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica cyclin-dependent kinase protein, putative 0.000804072 0 0.5
Giardia lamblia Kinase, STE STE11 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.000804072 0 0.5
Giardia lamblia Kinase, AGC PKA 0.000804072 0 0.5
Plasmodium vivax EKC/KEOPS complex subunit BUD32, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi serine/threonine protein kinase, putative 0.000804072 0 0.5
Onchocerca volvulus Protein kinase homolog 0.000804072 0 0.5
Trypanosoma cruzi rac serine-threonine kinase, putative 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, CAMK CAMKL 0.000804072 0 0.5
Entamoeba histolytica serine/threonine protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, ULK 0.000804072 0 0.5
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase kinase kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Cell division protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi Serine/threonine-protein kinase VPS15, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi mitogen-activated protein kinase 5, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Trypanosoma cruzi cdc2-related kinase 12 0.000804072 0 0.5
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0207793 0.0582213 0.0582213
Echinococcus granulosus cGMP dependent protein kinase 1 0.0013067 0.00146499 0.00146499
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Plasmodium vivax serine/threonine protein kinase, FIKK family 0.000804072 0 0.5
Entamoeba histolytica casein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Entamoeba histolytica protein kinase domain containing protein 0.000804072 0 0.5
Onchocerca volvulus 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Plasmodium vivax protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.000804072 0 0.5
Plasmodium vivax glycogen synthase kinase 3, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-like 0.000804072 0 0.5
Trypanosoma cruzi MEKK-related kinase 1, putative 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK-like 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica hypothetical protein 0.000804072 0 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.000804072 0 0.5
Trypanosoma cruzi protein kinase, putative 0.000804072 0 0.5
Entamoeba histolytica serine/threonine- protein kinase C823.03, putative 0.000804072 0 0.5
Trypanosoma cruzi hypothetical protein 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5
Giardia lamblia Kinase, CAMK CAMKL 0.000804072 0 0.5
Giardia lamblia Kinase, CAMK CAMK1 0.000804072 0 0.5
Trypanosoma cruzi NAK family pseudokinase, putative 0.000804072 0 0.5
Giardia lamblia Kinase, NEK 0.000804072 0 0.5
Giardia lamblia Kinase 0.000804072 0 0.5

Activities

Activity type Activity value Assay description Source Reference
Fu (ADMET) = 5.1 % Unbound fraction in human plasma ChEMBL. 25007124
IC50 (functional) = 0.017 uM Antiplasmodial activity against Plasmodium falciparum NF54 by SYBR-green based assay ChEMBL. 25007124
IC50 (functional) = 0.026 uM Antiplasmodial activity against Plasmodium falciparum K1 by SYBR-green based assay ChEMBL. 25007124
IC50 (binding) = 8.8 uM Inhibition of human ERG ChEMBL. 25007124

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum 25007124

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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