Detailed information for compound 924337

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 592.944 | Formula: C28H32Cl3N5O3
  • H donors: 2 H acceptors: 2 LogP: 5.37 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: CNCCNC(=O)CN(c1cc(Cl)ccc1Oc1ccc(cc1)Cl)CC(=O)N(N1Cc2c(C1)cccc2)C.Cl
  • InChi: 1S/C28H31Cl2N5O3.ClH/c1-31-13-14-32-27(36)18-34(19-28(37)33(2)35-16-20-5-3-4-6-21(20)17-35)25-15-23(30)9-12-26(25)38-24-10-7-22(29)8-11-24;/h3-12,15,31H,13-14,16-19H2,1-2H3,(H,32,36);1H
  • InChiKey: SKNNHBJXLUMONV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adenosylhomocysteinase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Cryptosporidium parvum S-adenosylhomocysteinase Get druggable targets OG5_127233 All targets in OG5_127233
Entamoeba histolytica adenosylhomocysteinase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Babesia bovis adenosylhomocysteinase (S-adenosyl-L-homocysteinehydrolase) Get druggable targets OG5_127233 All targets in OG5_127233
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH Get druggable targets OG5_127233 All targets in OG5_127233
Plasmodium knowlesi adenosylhomocysteinase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Leishmania infantum S-adenosylhomocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
Loa Loa (eye worm) adenosylhomocysteinase Get druggable targets OG5_127233 All targets in OG5_127233
Brugia malayi Adenosylhomocysteinase Get druggable targets OG5_127233 All targets in OG5_127233
Leishmania braziliensis S-adenosylhomocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
Theileria parva S-adenosyl-L-homocysteine hydrolase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Plasmodium yoelii adenosylhomocysteinase Get druggable targets OG5_127233 All targets in OG5_127233
Candida albicans Putative S-adenosyl-L-homocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
Cryptosporidium hominis adenosylhomocysteinase Get druggable targets OG5_127233 All targets in OG5_127233
Schistosoma mansoni adenosylhomocysteinase Get druggable targets OG5_127233 All targets in OG5_127233
Leishmania donovani S-adenosylhomocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) Get druggable targets OG5_127233 All targets in OG5_127233
Plasmodium berghei adenosylhomocysteinase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Trypanosoma brucei gambiense S-adenosylhomocysteine hydrolase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Trichomonas vaginalis adenosylhomocysteinase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Trypanosoma congolense S-adenosylhomocysteine hydrolase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Plasmodium falciparum adenosylhomocysteinase Get druggable targets OG5_127233 All targets in OG5_127233
Trichomonas vaginalis adenosylhomocysteinase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Toxoplasma gondii S-Adenosyl homocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
Trypanosoma congolense S-adenosylhomocysteine hydrolase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Toxoplasma gondii adenosylhomocysteinase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Schistosoma japonicum ko:K01251 adenosylhomocysteinase [EC3.3.1.1], putative Get druggable targets OG5_127233 All targets in OG5_127233
Leishmania mexicana S-adenosylhomocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
Leishmania major S-adenosylhomocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
Echinococcus granulosus adenosylhomocysteinase Get druggable targets OG5_127233 All targets in OG5_127233
Candida albicans Putative S-adenosyl-L-homocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
Echinococcus multilocularis adenosylhomocysteinase Get druggable targets OG5_127233 All targets in OG5_127233
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative Get druggable targets OG5_127233 All targets in OG5_127233
Neospora caninum hypothetical protein Get druggable targets OG5_127233 All targets in OG5_127233
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative Get druggable targets OG5_127233 All targets in OG5_127233
Leishmania braziliensis S-adenosylhomocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase Get druggable targets OG5_127233 All targets in OG5_127233
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0079 0.0019 0.0457
Schistosoma mansoni z-protein (S1r protein) 0.0012 0.0002 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0278 0.0071 0.116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.0071 0.1688
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0005 0.00000000000061919 0.000000000014796
Echinococcus granulosus mothers against decapentaplegic 5 0.0019 0.0004 0.0086
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0278 0.0071 0.1688
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0049 0.0011 0.0271
Brugia malayi Regulator of G protein signaling domain containing protein 0.0012 0.0002 0.0039
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0004 0.0004
Echinococcus multilocularis neuropeptides capa receptor 0.0278 0.0071 0.116
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0 0.0007
Echinococcus granulosus thymidylate synthase 0.0367 0.0094 0.2237
Leishmania major cytochrome p450-like protein 0.0007 0 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.0071 0.1688
Echinococcus multilocularis neuropeptide FF receptor 2 0.0278 0.0071 0.116
Treponema pallidum adenine phosphoribosyltransferase 0.0043 0.001 0.0026
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0008 0.0001 0.0013
Brugia malayi UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 0.0049 0.0011 0.0271
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Brugia malayi Dopamine receptor 0.0278 0.0071 0.1688
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0042 0.0009 0.0225
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0094 0.0023 0.0549
Loa Loa (eye worm) glutathione reductase 0.0059 0.0014 0.0333
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0019
Toxoplasma gondii HEAT repeat-containing protein 0.0022 0.0004 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.0071 0.1688
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0021 0.0004 0.0099
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0006 0 0.0002
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0001 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.0071 0.116
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Treponema pallidum exodeoxyribonuclease (exoA) 0.005 0.0012 0.003
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0001 0.0029
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Loa Loa (eye worm) G-protein coupled receptor 0.0278 0.0071 0.1688
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0135 0.0034 0.0034
Echinococcus multilocularis beta 1,4 N acetylgalactosaminyltransferase 0.0026 0.0005 0.0089
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0016 0.0003 0.0045
Mycobacterium tuberculosis Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) 0.0188 0.0047 0.0047
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0211 0.0053 0.1275
Brugia malayi MH2 domain containing protein 0.0284 0.0072 0.1723
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0156 0.0039 0.0933
Echinococcus granulosus beta 14 N acetylgalactosaminyltransferase 0.0026 0.0005 0.0129
Plasmodium vivax hypothetical protein, conserved 0.001 0.0001 0.0029
Brugia malayi Galactosyltransferase family protein 0.0026 0.0005 0.0129
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0004 0.0093
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.0513 0.0132 0.0132
Plasmodium falciparum thioredoxin reductase 0.002 0.0004 0.0093
Echinococcus granulosus Ribosomal protein L34a 0.0074 0.0018 0.0423
Giardia lamblia O-linked GlcNAc transferase 0.0049 0.0011 0.0269
Mycobacterium tuberculosis Conserved hypothetical protein 0.0094 0.0023 0.0023
Echinococcus multilocularis g-protein coupled receptor 0.0278 0.0071 0.116
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0018 0.0003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0039
Schistosoma mansoni biogenic amine receptor 0.0278 0.0071 0.1688
Onchocerca volvulus 0.1621 0.0418 0.8582
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0004 0.0099
Echinococcus multilocularis neutral sphingomyelinase 0.001 0.0001 0.002
Schistosoma mansoni hypothetical protein 0.0278 0.0071 0.1688
Onchocerca volvulus DNA polymerase homolog 0.0009 0.0001 0.0019
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0029
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0003 0.0076
Echinococcus granulosus peptide allatostatin:somatostatin 0.0278 0.0071 0.1688
Giardia lamblia Deoxynucleoside kinase 0.1103 0.0284 0.6794
Trichomonas vaginalis AGC family protein kinase 0.0142 0.0035 0.0848
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0002 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0039
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0009 0.0001 0.0022
Onchocerca volvulus 0.001 0.0001 0.0025
Echinococcus multilocularis mothers against decapentaplegic 2 0.0009 0.0001 0.0014
Trypanosoma brucei UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.1621 0.0418 1
Toxoplasma gondii phosphofructokinase PFKII 0.0021 0.0004 0.0099
Schistosoma mansoni smad 0.0019 0.0004 0.0086
Brugia malayi follicle stimulating hormone receptor 0.0429 0.011 0.2625
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0278 0.0071 0.116
Echinococcus granulosus Na+ dependent nucleoside transporter 0.0415 0.0106 0.2535
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0012 0.0002 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0278 0.0071 0.1688
Brugia malayi cytidine deaminase, identical 0.0065 0.0015 0.0368
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0009 0.0001 0.0022
Brugia malayi RE15519p 0.0278 0.0071 0.1688
Loa Loa (eye worm) globin family protein 0.001 0.0001 0.0025
Mycobacterium tuberculosis Probable monooxygenase 0.001 0.0001 0.0001
Toxoplasma gondii cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein 0.0065 0.0015 0.0368
Mycobacterium ulcerans amidophosphoribosyltransferase 0.0043 0.001 0.001
Echinococcus multilocularis snurportin 1 0.0234 0.0059 0.0971
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0003 0.0076
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.001 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0005 0.000003751 0.0001
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0026 0.0005 0.0129
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0002 0.0043
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0003 0.0076
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0367 0.0094 0.2237
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0577 0.0148 0.3538
Brugia malayi Tachykinin-like peptides receptor 99D 0.0278 0.0071 0.1688
Onchocerca volvulus 0.0065 0.0015 0.0315
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Schistosoma mansoni ryanodine receptor related 0.005 0.0011 0.0274
Schistosoma mansoni mixed-lineage leukemia protein mll 0.005 0.0011 0.0273
Trichomonas vaginalis phosphofructokinase, putative 0.0079 0.0019 0.0458
Echinococcus granulosus thymidine phosphorylase 0.0513 0.0132 0.3143
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0021 0.0004 0.0099
Schistosoma mansoni hypothetical protein 0.0234 0.0059 0.1414
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0009 0.0001 0.0023
Onchocerca volvulus 0.0065 0.0015 0.0315
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0005 0.00000000000061919 0.000000000014796
Plasmodium falciparum adenosylhomocysteinase 0.0156 0.0039 0.0933
Brugia malayi beta-1,4-galactosyltransferase VII 0.0026 0.0005 0.0129
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0003 0.0076
Brugia malayi AKH receptor 0.0278 0.0071 0.1688
Schistosoma mansoni beta-14-galactosyltransferase 34-related 0.0011 0.0001 0.0033
Schistosoma mansoni DNA helicase recq1 0.0006 0 0.0002
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.015 0.0037 0.0037
Loa Loa (eye worm) TYRA-2 protein 0.0278 0.0071 0.1688
Brugia malayi cytoplasmic intermediate filament protein 0.001 0.0001 0.0025
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0004 0.0093
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0004 0.01
Treponema pallidum hypothetical protein 0.0019 0.0004 0.0009
Brugia malayi Globin family protein 0.001 0.0001 0.0025
Mycobacterium tuberculosis Probable oxidoreductase 0.015 0.0037 0.0037
Schistosoma mansoni transcription factor LCR-F1 0.0094 0.0023 0.0549
Onchocerca volvulus Adenine phosphoribosyltransferase homolog 0.0043 0.001 0.0201
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0004 0.0093
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0003 0.0076
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.005 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Schistosoma mansoni lamin 0.0018 0.0003 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.0071 0.1688
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Echinococcus multilocularis 6 phosphofructokinase 0.0079 0.0019 0.0314
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.001 0.0001 0.003
Mycobacterium leprae Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase) 0.0536 0.0138 0.0138
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Echinococcus multilocularis mothers against decapentaplegic 5 0.0019 0.0004 0.0059
Onchocerca volvulus 0.0008 0.0001 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0004 0.0093
Brugia malayi Cytochrome P450 family protein 0.0007 0 0.0007
Onchocerca volvulus 0.001 0.0001 0.0022
Echinococcus multilocularis Ribosomal protein L34a 0.0074 0.0018 0.0291
Schistosoma mansoni axis inhibition protein axin 0.0012 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Schistosoma mansoni orotidine 5'-phosphate decarboxylase 0.058 0.0149 0.3554
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.001 0.0001 0.0029
Brugia malayi dihydrofolate reductase family protein 0.0395 0.0101 0.2413
Mycobacterium tuberculosis Probable exported protein 0.001 0.0001 0.0001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0278 0.0071 0.1688
Brugia malayi Melatonin receptor type 1A 0.0278 0.0071 0.1688
Onchocerca volvulus Neuropeptide F receptor homolog 0.0278 0.0071 0.1449
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0002 0.0043
Schistosoma mansoni cellular tumor antigen P53 0.0036 0.0008 0.0191
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0009 0.0001 0.0015
Trichomonas vaginalis ran, putative 0.0016 0.0003 0.0067
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.001 0.0001 0.0029
Schistosoma mansoni n-acetylgalactosaminyltransferase 0.0011 0.0001 0.0033
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Loa Loa (eye worm) G-protein coupled receptor 0.0278 0.0071 0.1688
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.005 0.0012 0.0276
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0004 0.0011
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.001 0.0001 0.0029
Echinococcus granulosus neuropeptides capa receptor 0.0278 0.0071 0.1688
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Toxoplasma gondii O-linked N-acetylglucosamine transferase 0.0049 0.0011 0.0269
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.0071 0.1688
Echinococcus granulosus g protein coupled receptor 0.0278 0.0071 0.1688
Echinococcus granulosus Metazoa galactosyltransferase 0.01 0.0025 0.0586
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0003 0.0076
Mycobacterium ulcerans adenine phosphoribosyltransferase 0.0043 0.001 0.001
Schistosoma mansoni neuropeptide f receptor 76f 0.0278 0.0071 0.1688
Onchocerca volvulus 0.0278 0.0071 0.1449
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0004 0.0093
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0076
Schistosoma mansoni beta-14-galactosyltransferase 0.0026 0.0005 0.0129
Echinococcus multilocularis g protein coupled receptor 0.0278 0.0071 0.116
Schistosoma mansoni smad1 5 8 and 0.0019 0.0004 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0278 0.0071 0.116
Trichomonas vaginalis thymidine kinase, putative 0.0148 0.0037 0.0882
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0005 0.000003751 0.0001
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0012 0.0002 0.0043
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0009 0.0001 0.0025
Loa Loa (eye worm) PXA domain-containing protein 0.0012 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Echinococcus multilocularis neuropeptide Y receptor 0.0278 0.0071 0.116
Brugia malayi hypothetical protein 0.001 0.0001 0.0025
Schistosoma mansoni ap endonuclease 0.005 0.0012 0.0276
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0009 0.0001 0.0019
Wolbachia endosymbiont of Brugia malayi phospho-N-acetylmuramoyl-pentapeptide-transferase 3.8606 1 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0278 0.0071 0.1688
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Schistosoma mansoni hypothetical protein 0.0278 0.0071 0.1688
Mycobacterium ulcerans 6-phosphofructokinase 0.0079 0.0019 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.0071 0.1688
Toxoplasma gondii histone lysine methyltransferase SET1 0.0044 0.001 0.024
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0013 0.0313
Echinococcus granulosus UDP N acetylglucosamine dolichyl phosphate 0.1621 0.0418 1
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.001 0.0001 0.0029
Brugia malayi A-kinase anchor protein 10, precursor 0.0012 0.0002 0.0039
Trichomonas vaginalis mannosyltransferase 1, putative 0.0008 0.0001 0.0015
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.005 0.0012 0.0276
Loa Loa (eye worm) thymidylate synthase 0.0367 0.0094 0.2237
Schistosoma mansoni opsin-like receptor 0.0278 0.0071 0.1688
Giardia lamblia Hypothetical protein 0.0211 0.0053 0.1275
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0004 0.0093
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Echinococcus granulosus alpha 1A adrenergic receptor 0.0278 0.0071 0.1688
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0367 0.0094 0.0094
Mycobacterium ulcerans monooxygenase 0.001 0.0001 0.0001
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.015 0.0037 0.0037
Onchocerca volvulus 0.0278 0.0071 0.1449
Brugia malayi MH1 domain containing protein 0.0011 0.0001 0.0033
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0016 0.0003 0.0066
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0004 0.0093
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0014 0.0002 0.0054
Echinococcus granulosus tm gpcr rhodopsin 0.0278 0.0071 0.1688
Brugia malayi Dopamine receptor protein 2 0.0278 0.0071 0.1688
Loa Loa (eye worm) CXXC zinc finger family protein 0.0023 0.0005 0.0111
Schistosoma mansoni hypothetical protein 0.0278 0.0071 0.1688
Schistosoma mansoni beta-14-galactosyltransferase 0.0016 0.0003 0.0062
Loa Loa (eye worm) histone methyltransferase 0.0007 0.0001 0.0011
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.005 0.0011 0.0274
Echinococcus multilocularis regulator of G protein signaling 7 0.0012 0.0002 0.0027
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0009 0.0001 0.0022
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Leishmania major importin beta-1 subunit, putative 0.0018 0.0003 0.0076
Plasmodium falciparum importin beta, putative 0.0022 0.0004 0.0102
Brugia malayi MH1 domain containing protein 0.0019 0.0004 0.0086
Trichomonas vaginalis phosphofructokinase, putative 0.0079 0.0019 0.0458
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0009 0.0001 0.0022
Schistosoma mansoni biogenic amine receptor 0.0278 0.0071 0.1688
Onchocerca volvulus 0.0367 0.0094 0.192
Trypanosoma cruzi mitochondrial protein 99, putative 0.001 0.0001 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0004 0.0093
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.001 0.0001 0.0029
Mycobacterium leprae PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) 0.0065 0.0015 0.0015
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0012 0.0002 0.0039
Echinococcus multilocularis cpg binding protein 0.0025 0.0005 0.0082
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.058 0.0149 0.3554
Brugia malayi MH2 domain containing protein 0.0019 0.0004 0.0086
Echinococcus granulosus Thymidine kinase 2 mitochondrial 0.1593 0.0411 0.9827
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0005 0.000003751 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0039
Brugia malayi Cytochrome P450 family protein 0.0007 0 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.0142 0.0035 0.0847
Brugia malayi putative neuropeptide receptor 0.0278 0.0071 0.1688
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0003 0.0052
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0062 0.0015 0.0348
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0001 0.0024
Echinococcus granulosus adenine phosphoribosyltransferase 0.0043 0.001 0.0234
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.001 0.0001 0.0029
Leishmania major adenylate cyclase-like protein 0.001 0.0001 0.0025
Schistosoma mansoni cpg binding protein 0.0025 0.0005 0.0119
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.005 0.0012 0.0276
Echinococcus multilocularis neuropeptide Y receptor 0.0278 0.0071 0.116
Echinococcus granulosus g-protein coupled receptor 0.0278 0.0071 0.1688
Trichomonas vaginalis phosphofructokinase, putative 0.0079 0.0019 0.0458
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0004 0.0093
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.005 0.0012 0.0276
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.001 0.0001 0.0029
Echinococcus multilocularis neuropeptide receptor A26 0.0578 0.0148 0.2435
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0039
Loa Loa (eye worm) MIR domain-containing protein 0.0008 0.0001 0.0014
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.005 0.0012 0.0276
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0004 0.0094
Loa Loa (eye worm) RecQ helicase 0.0014 0.0002 0.0053
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Entamoeba histolytica hypothetical protein 0.0211 0.0053 0.1275
Schistosoma mansoni amine GPCR 0.0278 0.0071 0.1688
Trypanosoma cruzi thymidine kinase, putative 0.0148 0.0037 0.0881
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0004 0.01
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0006 0 0.0002
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0006 0 0.0002
Mycobacterium ulcerans hypoxanthine-guanine phosphoribosyltransferase Hpt 0.0043 0.001 0.001
Leishmania major thymidine kinase, putative 0.0148 0.0037 0.0881
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Brugia malayi intermediate filament protein 0.0018 0.0003 0.0076
Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT 0.0043 0.001 0.0234
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0032 0.0007 0.0167
Entamoeba histolytica exodeoxyribonuclease III, putative 0.005 0.0012 0.0276
Echinococcus multilocularis thymidine phosphorylase 0.0513 0.0132 0.216
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0278 0.0071 0.116
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.0053 0.1276
Echinococcus granulosus TGF beta signal transducer SmadC 0.0019 0.0004 0.0086
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0005 0.000003751 0.0001
Trypanosoma cruzi importin beta-1 subunit, putative 0.0018 0.0003 0.0076
Leishmania major trypanothione reductase 0.0059 0.0014 0.0333
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0043 0.001 0.0161
Echinococcus granulosus traf and tnf receptor associated protein 0.001 0.0001 0.0029
Mycobacterium ulcerans thymidylate synthase 0.0367 0.0094 0.0094
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.001 0.0001 0.0029
Echinococcus multilocularis tumor protein p63 0.0248 0.0063 0.103
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0278 0.0071 0.116
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0003 0.0052
Toxoplasma gondii cytochrome p450 superfamily protein 0.0007 0 0.0007
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0038 0.0009 0.0204
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.001 0.0001 0.0029
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.0142 0.0035 0.0843
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0018 0.0003 0.0077
Leishmania major xanthine phosphoribosyltransferase 0.0043 0.001 0.0234
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0009 0.0001 0.0022
Echinococcus granulosus mixed lineage leukemia protein mll 0.0006 0 0.0002
Echinococcus granulosus beta 14 galactosyltransferase 7 0.0026 0.0005 0.0129
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.015 0.0037 0.0037
Schistosoma mansoni neuropeptide F-like receptor 0.0278 0.0071 0.1688
Mycobacterium tuberculosis Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.0043 0.001 0.001
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2357 0.0609 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Schistosoma mansoni neuropeptide F-like receptor 0.0278 0.0071 0.1688
Leishmania major pantothenate kinase subunit, putative 0.001 0.0001 0.0029
Echinococcus granulosus 7tm_1 domain containing protein 0.0278 0.0071 0.1688
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0021 0.0004 0.0099
Echinococcus granulosus cytochrome P450 2K1 0.0007 0 0.0007
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0004 0.0094
Loa Loa (eye worm) orotate phosphoribosyltransferase 0.058 0.0149 0.3554
Echinococcus multilocularis G protein coupled receptor 139 0.0278 0.0071 0.116
Brugia malayi orotate phosphoribosyltransferase family protein 0.058 0.0149 0.3554
Onchocerca volvulus 0.0023 0.0005 0.0095
Schistosoma mansoni ap endonuclease 0.005 0.0012 0.0276
Brugia malayi hypothetical protein 0.001 0.0001 0.0025
Plasmodium falciparum orotidine 5'-phosphate decarboxylase 0.0536 0.0138 0.3287
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0002 0.0035
Echinococcus multilocularis dihydrofolate reductase 0.0395 0.0101 0.1658
Echinococcus granulosus thymidine kinase 0.1593 0.0411 0.9827
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0004 0.0093
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0008 0.0001 0.0014
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0278 0.0071 0.1688
Trichomonas vaginalis thymidine kinase, putative 0.0148 0.0037 0.0882
Wolbachia endosymbiont of Brugia malayi orotate phosphoribosyltransferase 0.0188 0.0047 0.0047
Mycobacterium tuberculosis Probable reductase 0.0135 0.0034 0.0034
Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Entamoeba histolytica hypothetical protein 0.0094 0.0023 0.0549
Brugia malayi regulator of G-protein signaling egl-10 0.0012 0.0002 0.0039
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0003 0.0052
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0044 0.001 0.0207
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0094 0.0023 0.0377
Leishmania major adenine phosphoribosyltransferase 0.0043 0.001 0.0234
Brugia malayi MH1 domain containing protein 0.0019 0.0004 0.0086
Schistosoma mansoni neuropeptide receptor 0.0278 0.0071 0.1688
Brugia malayi exodeoxyribonuclease III family protein 0.005 0.0012 0.0276
Treponema pallidum NADH oxidase 0.002 0.0004 0.001
Brugia malayi hypothetical protein 0.001 0.0001 0.0025
Brugia malayi Regulator of G protein signaling domain containing protein 0.0012 0.0002 0.0039
Schistosoma mansoni lamin 0.0018 0.0003 0.0076
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Loa Loa (eye worm) adenine phosphoribosyltransferase 0.0043 0.001 0.0234
Loa Loa (eye worm) MH2 domain-containing protein 0.0009 0.0001 0.002
Echinococcus multilocularis stromal cell derived factor 2 0.0008 0.0001 0.001
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Echinococcus multilocularis Smad4 0.0019 0.0004 0.0059
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0006 0 0.0002
Entamoeba histolytica hypothetical protein 0.0211 0.0053 0.1275
Leishmania major UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.1621 0.0418 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0008 0.0186
Loa Loa (eye worm) MH1 domain-containing protein 0.0009 0.0001 0.002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0135 0.0034 0.0034
Brugia malayi neuropeptide F receptor 0.0278 0.0071 0.1688
Loa Loa (eye worm) melatonin receptor type 1A 0.0278 0.0071 0.1688
Brugia malayi MIR domain containing protein 0.0008 0.0001 0.0014
Mycobacterium ulcerans hypothetical protein 0.0043 0.001 0.001
Brugia malayi G protein-coupled receptor F59B2.13 0.0278 0.0071 0.1688
Mycobacterium ulcerans cytidine deaminase 0.0065 0.0015 0.0015
Onchocerca volvulus 0.0278 0.0071 0.1449
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0006 0 0.0002
Echinococcus multilocularis thymidine kinase 0.1593 0.0411 0.6752
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0001 0.0029
Trichomonas vaginalis cytidine deaminase, putative 0.0065 0.0015 0.0368
Plasmodium vivax orotate phosphoribosyltransferase, putative 0.0188 0.0047 0.1129
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0367 0.0094 0.0094
Schistosoma mansoni Smad4 0.0009 0.0001 0.002
Brugia malayi hypothetical protein 0.0037 0.0008 0.0194
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0004 0.0086
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0079 0.0019 0.0019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.011 0.0027 0.0646
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0018 0.0003 0.0077
Echinococcus granulosus fmrfamide receptor 0.0278 0.0071 0.1688
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0013 0.0002 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.0071 0.1688
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0021 0.0004 0.01
Brugia malayi hypothetical protein 0.001 0.0001 0.0025
Onchocerca volvulus 0.0278 0.0071 0.1449
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0016 0.0003 0.0066
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0003 0.0052
Mycobacterium tuberculosis Conserved protein 0.0043 0.001 0.001
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.001 0.0001 0.003
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0004 0.0004
Onchocerca volvulus 0.0278 0.0071 0.1449
Echinococcus multilocularis regulator of G protein signaling 3 0.0012 0.0002 0.0027
Echinococcus granulosus neuropeptides capa receptor 0.0278 0.0071 0.1688
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0076
Toxoplasma gondii LsmAD domain-containing protein 0.0057 0.0013 0.0319
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0001 0.0029
Schistosoma mansoni opsin-like receptor 0.0278 0.0071 0.1688
Schistosoma mansoni cript-related 0.001 0.0001 0.0029
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0266
Trypanosoma cruzi trypanothione reductase, putative 0.0059 0.0014 0.0333
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0074
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0012 0.0002 0.0039
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0278 0.0071 0.1688
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0004 0.0093
Echinococcus multilocularis ryanodine receptor 44f 0.0028 0.0006 0.0094
Echinococcus granulosus geminin 0.0767 0.0197 0.4714
Echinococcus multilocularis regulator of G protein signaling 3 0.0012 0.0002 0.0027
Brugia malayi glutathione reductase 0.0059 0.0014 0.0333
Entamoeba histolytica hypothetical protein 0.0211 0.0053 0.1275
Giardia lamblia Thymidine kinase 0.0148 0.0037 0.0881
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0044 0.001 0.0242
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0211 0.0053 0.1275
Loa Loa (eye worm) hypothetical protein 0.004 0.0009 0.0216
Brugia malayi larval opioid receptor 0.0278 0.0071 0.1688
Trichomonas vaginalis ribose-phosphate pyrophosphokinase, putative 0.0043 0.001 0.0235
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0009 0.0001 0.0013
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0156 0.0039 0.0039
Echinococcus multilocularis axis inhibition protein axin 0.0012 0.0002 0.0027
Toxoplasma gondii adenosylhomocysteinase, putative 0.0156 0.0039 0.0933
Leishmania major hypoxanthine-guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0135 0.0034 0.0034
Brugia malayi G protein-coupled receptor 0.0278 0.0071 0.1688
Entamoeba histolytica Ran family GTPase 0.0016 0.0003 0.0066
Schistosoma mansoni beta-14-galactosyltransferase 0.0026 0.0005 0.0129
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0001 0.0029
Wolbachia endosymbiont of Brugia malayi orotidine-5'-phosphate decarboxylase 0.2279 0.0589 0.0589
Mycobacterium tuberculosis Probable dehydrogenase 0.0135 0.0034 0.0034
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0278 0.0071 0.116
Trypanosoma cruzi PAB1-binding protein , putative 0.0057 0.0013 0.0319
Echinococcus granulosus somatostatin receptor 0.0278 0.0071 0.1688
Onchocerca volvulus 0.0278 0.0071 0.1449
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0004 0.0011
Entamoeba histolytica hypothetical protein 0.0094 0.0023 0.0549
Trichomonas vaginalis Ribose-phosphate pyrophosphokinase, putative 0.0043 0.001 0.0235
Brugia malayi PXA domain containing protein 0.0012 0.0002 0.0039
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0009 0.0001 0.0022
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0001 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0005 0.00000000000061919 0.000000000014796
Leishmania major hypothetical protein, conserved 0.001 0.0001 0.0029
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.001 0.0001 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0029
Trypanosoma brucei trypanothione reductase 0.0059 0.0014 0.0333
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0008 0.0001 0.0013
Toxoplasma gondii N-acetylgalactosaminyl transferase 0.0011 0.0001 0.0033
Schistosoma mansoni amine GPCR 0.0278 0.0071 0.1688
Toxoplasma gondii glycosyl transferase 0.0011 0.0001 0.0033
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.0145 0.0036 0.0036
Mycobacterium tuberculosis Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) 0.0065 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.0071 0.1688
Echinococcus granulosus smad 0.0019 0.0004 0.0086
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Brugia malayi hypothetical protein 0.0012 0.0002 0.0039
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0211 0.0053 0.1275
Treponema pallidum hypothetical protein 0.001 0.0001 0.0003
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0004 0.0004
Mycobacterium ulcerans bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 0.0043 0.001 0.001
Brugia malayi Intermediate filament tail domain containing protein 0.0018 0.0003 0.0076
Onchocerca volvulus 0.0036 0.0008 0.0164
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Schistosoma mansoni regulator of G protein signaling 0.0012 0.0002 0.0039
Schistosoma mansoni amine GPCR 0.0278 0.0071 0.1688
Echinococcus granulosus mothers against decapentaplegic 2 0.0009 0.0001 0.002
Schistosoma mansoni hypothetical protein 0.0108 0.0027 0.0637
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0029
Plasmodium falciparum ataxin-2 like protein, putative 0.0057 0.0013 0.0319
Echinococcus multilocularis G-protein coupled receptor, putative 0.0278 0.0071 0.116
Leishmania major S-adenosylhomocysteine hydrolase 0.0156 0.0039 0.0933
Schistosoma mansoni uracil phosphoribosyltransferase 0.0043 0.001 0.0234
Brugia malayi 6-phosphofructokinase 0.0079 0.0019 0.0457
Echinococcus multilocularis orexin receptor type 2 0.0278 0.0071 0.116
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0278 0.0071 0.1688
Schistosoma mansoni regulator of G protein signaling 0.0012 0.0002 0.0039
Trichomonas vaginalis STE family protein kinase 0.0142 0.0035 0.0848
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.001 0.0001 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0004 0.0093
Onchocerca volvulus 0.017 0.0043 0.0874
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0278 0.0071 0.116
Onchocerca volvulus Putative neutral sphingomyelinase 0.001 0.0001 0.0025
Brugia malayi Globin family protein 0.001 0.0001 0.0025
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0278 0.0071 0.1688
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0004 0.0093
Onchocerca volvulus 0.0278 0.0071 0.1449
Schistosoma mansoni beta-14-galactosyltransferase 0.0026 0.0005 0.0129
Echinococcus multilocularis adenosylhomocysteinase 0.0156 0.0039 0.0641
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0079 0.0019 0.0457
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0014 0.0002 0.0054
Onchocerca volvulus 0.0018 0.0003 0.0065
Mycobacterium ulcerans orotidine 5'-phosphate decarboxylase 0.0536 0.0138 0.0138
Echinococcus granulosus ryanodine receptor 44f 0.0035 0.0008 0.0186
Echinococcus granulosus neuropeptide receptor A26 0.0578 0.0148 0.3544
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.001 0.0001 0.0029
Brugia malayi regulator of G-protein signaling rgs-7 0.0012 0.0002 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.0071 0.116
Schistosoma mansoni regulator of G protein signaling 0.0012 0.0002 0.0039
Schistosoma mansoni 6-phosphofructokinase 0.0079 0.0019 0.0457
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0156 0.0039 0.0933
Brugia malayi hypothetical protein 0.0094 0.0023 0.0549
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.001 0.0001 0.0029
Giardia lamblia Cytidine deaminase 0.0065 0.0015 0.0368
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0043 0.001 0.0234
Brugia malayi G-protein coupled receptor 0.0278 0.0071 0.1688
Onchocerca volvulus 0.0278 0.0071 0.1449
Trypanosoma brucei RNA editing exonuclease 2 0.001 0.0001 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0039
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.001 0.0001 0.0029
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.001 0.0001 0.0029
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.0071 0.1688
Plasmodium vivax DNA polymerase alpha, putative 0.0026 0.0005 0.0129
Echinococcus multilocularis neuropeptide s receptor 0.0578 0.0148 0.2435
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0002 0.0043
Echinococcus multilocularis uridine 5' monophosphate synthase 0.058 0.0149 0.2442
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0039
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.005 0.0012 0.0276
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0005 0.000003751 0.0001
Onchocerca volvulus 0.0278 0.0071 0.1449
Treponema pallidum hypothetical protein 0.0019 0.0004 0.0009
Schistosoma mansoni hypothetical protein 0.0026 0.0005 0.0125
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.005 0.0012 0.0276
Echinococcus granulosus axis inhibition protein axin 0.0012 0.0002 0.0039
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Echinococcus granulosus bloom syndrome protein 0.0014 0.0002 0.0053
Schistosoma mansoni globin X 0.001 0.0001 0.0025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.011 0.0027 0.0444
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trichomonas vaginalis phosphofructokinase, putative 0.0079 0.0019 0.0458
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.1621 0.0418 1
Echinococcus granulosus intermediate filament protein 0.0018 0.0003 0.0076
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0004 0.0064
Trypanosoma brucei importin beta-1 subunit, putative 0.0022 0.0004 0.0102
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.001 0.0001 0.002
Echinococcus granulosus tumor protein p63 0.0248 0.0063 0.1499
Entamoeba histolytica hypothetical protein 0.0211 0.0053 0.1275
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.0071 0.1688
Plasmodium falciparum orotate phosphoribosyltransferase 0.0188 0.0047 0.1129
Trypanosoma brucei cytochrome P450, putative 0.0012 0.0002 0.0043
Leishmania major cytidine deaminase-like protein 0.0065 0.0015 0.0368
Echinococcus multilocularis serotonin receptor 0.0278 0.0071 0.116
Loa Loa (eye worm) transcription factor SMAD2 0.0284 0.0072 0.1723
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.0053 0.1276
Echinococcus multilocularis geminin 0.0767 0.0197 0.3239
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0004 0.0093
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Plasmodium vivax ataxin-2 like protein, putative 0.0057 0.0013 0.0319
Brugia malayi Serotonin receptor 0.0278 0.0071 0.1688
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.001 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0009 0.0001 0.0022
Leishmania major cytochrome p450-like protein 0.0007 0 0.0007
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0016 0.0003 0.0066
Schistosoma mansoni beta-14-galactosyltransferase 0.0026 0.0005 0.0129
Brugia malayi DNA polymerase family B containing protein 0.0009 0.0001 0.0022
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0016 0.0003 0.0066
Toxoplasma gondii glycosyl transferase, group 4 family protein 0.1621 0.0418 1
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Schistosoma mansoni DNA helicase recq5 0.0006 0 0.0002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.011 0.0027 0.0444
Loa Loa (eye worm) ryanodine receptor 0.0013 0.0002 0.0049
Schistosoma mansoni amine GPCR 0.0278 0.0071 0.1688
Schistosoma mansoni cytochrome P450 0.0007 0 0.0007
Brugia malayi CCR4 0.001 0.0001 0.0029
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0003 0.0076
Echinococcus granulosus mothers against decapentaplegic 6 0.0009 0.0001 0.002
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0278 0.0071 0.116
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0004 0.0004
Echinococcus multilocularis NADH ubiquinone oxidoreductase 42 kDa subunit 0.0211 0.0053 0.0876
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0005 0.00000000000061919 0.000000000014796
Treponema pallidum hypothetical protein 0.0019 0.0004 0.0009
Brugia malayi mothers against decapentaplegic homolog 3 0.0009 0.0001 0.002
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0003 0.0076
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0006 0 0.0002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0004 0.0093
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Loa Loa (eye worm) nuclear factor I 0.0011 0.0001 0.0033
Brugia malayi PXA domain containing protein 0.0012 0.0002 0.0039
Schistosoma mansoni ran 0.0016 0.0003 0.0066
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0278 0.0071 0.1688
Echinococcus granulosus lamin dm0 0.0018 0.0003 0.0076
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0012 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Entamoeba histolytica hypothetical protein 0.0094 0.0023 0.0549
Echinococcus granulosus 6 phosphofructokinase 0.0079 0.0019 0.0457
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0043 0.001 0.0161
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0429 0.011 0.2625
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0278 0.0071 0.116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.0071 0.116
Mycobacterium tuberculosis Conserved protein 0.0043 0.001 0.001
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Echinococcus granulosus solute carrier family 28 0.0415 0.0106 0.2535
Loa Loa (eye worm) 6-phosphofructokinase 0.0079 0.0019 0.0457
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Brugia malayi MH2 domain containing protein 0.0019 0.0004 0.0086
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Giardia lamblia Inositol 5-phosphatase 4 0.001 0.0001 0.0029
Schistosoma mansoni adenosylhomocysteinase 0.0097 0.0024 0.0565
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0002 0.0043
Echinococcus granulosus orexin receptor type 2 0.0278 0.0071 0.1688
Giardia lamblia UDP-N-acetylglucosamine-dolichyl-phosphateN-acetylglucosaminephosphotransferase 0.1621 0.0418 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0016 0.0003 0.0066
Echinococcus multilocularis concentrative Na+ nucleoside cotransporter 0.0415 0.0106 0.1742
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.058 0.0149 0.3554
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0004 0.0093
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0012 0.0002 0.0027
Trypanosoma brucei cytidine deaminase 0.0065 0.0015 0.0368
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0278 0.0071 0.116
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0009 0.0204
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0278 0.0071 0.1688
Echinococcus granulosus endonuclease exonuclease phosphatase 0.001 0.0001 0.0029
Schistosoma mansoni adenosylhomocysteinase 0.0156 0.0039 0.0933
Schistosoma mansoni growth hormone secretagogue receptor 0.0278 0.0071 0.1688
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0079 0.0019 0.0019
Schistosoma mansoni amine GPCR 0.0278 0.0071 0.1688
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.1621 0.0418 1
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.0145 0.0036 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0004 0.01
Schistosoma mansoni synaptojanin 0.001 0.0001 0.0029
Mycobacterium ulcerans undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe 0.1621 0.0418 0.0418
Echinococcus granulosus ryanodine receptor 44f 0.0028 0.0006 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0005 0.00000000000061919 0.000000000014796
Trichomonas vaginalis Phospholipase C precursor, putative 0.001 0.0001 0.003
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0004 0.0099
Onchocerca volvulus 0.0278 0.0071 0.1449
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.001 0.0001 0.002
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0395 0.0101 0.0101
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0006 0 0.0002
Trypanosoma cruzi pantothenate kinase subunit, putative 0.001 0.0001 0.0029
Echinococcus granulosus hypothetical protein 0.0278 0.0071 0.1688
Trypanosoma cruzi Eukaryotic translation initiation factor 2-alpha kinase 2 0.0142 0.0035 0.0847
Loa Loa (eye worm) hypothetical protein 0.0056 0.0013 0.0313
Brugia malayi Thioredoxin reductase 0.0059 0.0014 0.0333
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.001 0.0001 0.0029
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Toxoplasma gondii DNA polymerase 0.0009 0.0001 0.0022
Plasmodium vivax glutathione reductase, putative 0.0059 0.0014 0.0333
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0025
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0039
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Plasmodium falciparum DNase I-like protein, putative 0.001 0.0001 0.0029
Schistosoma mansoni o-linked n-acetylglucosamine transferase ogt 0.0049 0.0011 0.0272
Schistosoma mansoni carbon catabolite repressor protein 0.001 0.0001 0.0029
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.001 0.001
Onchocerca volvulus 0.0278 0.0071 0.1449
Echinococcus multilocularis lamin dm0 0.0018 0.0003 0.0052
Brugia malayi isocitrate dehydrogenase 0.0018 0.0003 0.0076
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0278 0.0071 0.1688
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0156 0.0039 0.0933
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0019 0.0004 0.0059
Brugia malayi hypothetical protein 0.017 0.0043 0.1018
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0026 0.0005 0.0086
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0278 0.0071 0.1688
Loa Loa (eye worm) neuropeptide F receptor 0.0278 0.0071 0.1688
Echinococcus granulosus tachykinin peptides receptor 99D 0.0278 0.0071 0.1688
Schistosoma mansoni neutral sphingomyelinase 0.001 0.0001 0.0029
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Echinococcus granulosus neuropeptide Y receptor 0.0278 0.0071 0.1688
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0009 0.0001 0.0022
Loa Loa (eye worm) deoxynucleoside kinase 0.0211 0.0053 0.1275
Schistosoma mansoni hypothetical protein 0.0094 0.0023 0.0549
Entamoeba histolytica phosphofructokinase, putative 0.0079 0.0019 0.0457
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0278 0.0071 0.1688
Schistosoma mansoni biogenic amine receptor 0.0278 0.0071 0.1688
Schistosoma mansoni beta-14-galactosyltransferase 0.01 0.0025 0.0586
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0006 0 0.0002
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0278 0.0071 0.1688
Echinococcus multilocularis thymidine kinase 0.1593 0.0411 0.6752
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0004 0.01
Toxoplasma gondii thioredoxin reductase 0.0059 0.0014 0.0333
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0014 0.0002 0.0054
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0 0.0007
Echinococcus granulosus tm gpcr rhodopsin 0.0278 0.0071 0.1688
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0001 0.0029
Echinococcus multilocularis transfer RNA-Ile 0.1593 0.0411 0.6752
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0009 0.0001 0.0022
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0001 0.0029
Loa Loa (eye worm) intermediate filament protein 0.0018 0.0003 0.0076
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0001 0.0029
Giardia lamblia Adenine phosphoribosyltransferase 0.0043 0.001 0.0234
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0009 0.0001 0.0022
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0135 0.0034 0.0034
Trichomonas vaginalis ap endonuclease, putative 0.005 0.0012 0.0277
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0033
Echinococcus multilocularis thymidylate synthase 0.0367 0.0094 0.1537
Echinococcus multilocularis Regulator of G protein signaling 20 0.0012 0.0002 0.0027
Plasmodium falciparum glutathione reductase 0.0059 0.0014 0.0333
Trypanosoma brucei PAB1-binding protein , putative 0.0057 0.0013 0.0319
Plasmodium falciparum glutathione reductase 0.002 0.0004 0.0093
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0025
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0026 0.0005 0.0125
Leishmania major hypothetical protein, conserved 0.001 0.0001 0.0029
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0278 0.0071 0.1688
Entamoeba histolytica UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.1621 0.0418 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0278 0.0071 0.1688
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.005 0.0012 0.0012
Echinococcus granulosus tm gpcr rhodopsin 0.0278 0.0071 0.1688
Plasmodium falciparum ataxin-2 like protein, putative 0.0057 0.0013 0.0319
Schistosoma mansoni axis inhibition protein axin 0.0012 0.0002 0.0039
Schistosoma mansoni beta-14-galactosyltransferase 0.0026 0.0005 0.0129
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.001 0.0001 0.003
Echinococcus granulosus G protein coupled receptor 139 0.0278 0.0071 0.1688
Schistosoma mansoni neuropeptide receptor 0.0278 0.0071 0.1688
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0025
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0395 0.0101 0.0101
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0278 0.0071 0.1688
Loa Loa (eye worm) glycosyl transferase 0.0011 0.0001 0.0033
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0577 0.0148 0.3538
Trichomonas vaginalis hypoxanthine-guanine phosphoribosyltransferase, putative 0.0043 0.001 0.0235
Echinococcus multilocularis UDP N acetylglucosamine dolichyl phosphate 0.1621 0.0418 0.687
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0079 0.0019 0.005
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0009 0.0001 0.0022
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0577 0.0148 0.3538
Loa Loa (eye worm) UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 0.0049 0.0011 0.0271
Echinococcus granulosus neuropeptide FF receptor 2 0.0278 0.0071 0.1688
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.011 0.0027 0.0646
Loa Loa (eye worm) beta-1,4-galactosyltransferase VII 0.0026 0.0005 0.0129
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0005 0.000003751 0.0001
Toxoplasma gondii 6-phosphofructokinase 0.0021 0.0004 0.0099
Loa Loa (eye worm) hypothetical protein 0.0047 0.0011 0.026
Echinococcus granulosus snurportin 1 0.0234 0.0059 0.1414
Mycobacterium ulcerans phospho-N-acetylmuramoyl-pentapeptide-transferase 3.8606 1 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0003 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.0053 0.1276
Trichomonas vaginalis glutamate synthase, putative 0.0005 0.000003751 0.0001
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0002 0.0054
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Schistosoma mansoni Smad4 0.0009 0.0001 0.002
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0577 0.0148 0.3538
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0001 0.0029
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0012 0.0002 0.0041
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0006 0 0.0002
Schistosoma mansoni hypothetical protein 0.0767 0.0197 0.4714
Schistosoma mansoni adenosylhomocysteinase 0.0097 0.0024 0.0565
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.0071 0.1688
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0004 0.0004
Chlamydia trachomatis dihydrofolate reductase 0.0395 0.0101 0.0266
Schistosoma mansoni neuropeptide receptor 0.0278 0.0071 0.1688
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0013 0.0313
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.0062
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0004 0.0093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0278 0.0071 0.1688
Echinococcus granulosus neuropeptide s receptor 0.0578 0.0148 0.3544
Treponema pallidum hypothetical protein 0.0019 0.0004 0.0009
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0005 0.00000000000061919 0.000000000014796
Mycobacterium tuberculosis Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (ompdecase) 0.0145 0.0036 0.0036
Echinococcus multilocularis GPCR, family 2 0.0018 0.0003 0.0052
Echinococcus granulosus synaptojanin 1 0.001 0.0001 0.0029
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0016 0.0003 0.0066
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0278 0.0071 0.1688
Brugia malayi ORL1-like opioid receptor 0.0278 0.0071 0.1688
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0135 0.0034 0.0034
Mycobacterium ulcerans thymidine phosphorylase 0.0513 0.0132 0.0132
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0009 0.0001 0.0017
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0002 0.0043
Echinococcus multilocularis importin subunit beta 1 0.0022 0.0004 0.007
Echinococcus granulosus dihydrofolate reductase 0.0395 0.0101 0.2413
Loa Loa (eye worm) neuropeptide F receptor 0.0278 0.0071 0.1688
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0076
Leishmania major hypothetical protein, conserved 0.0057 0.0013 0.0319
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.001 0.0001 0.0029
Schistosoma mansoni Smad4 0.0019 0.0004 0.0086
Mycobacterium ulcerans hypothetical protein 0.0019 0.0004 0.0004
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0174 0.0044 0.1047
Schistosoma mansoni beta-14-galactosyltransferase 0.01 0.0025 0.0586
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.0071 0.1688
Giardia lamblia Sgs1 DNA helicase, putative 0.0006 0 0.0002
Plasmodium falciparum exodeoxyribonuclease III, putative 0.001 0.0001 0.0029
Entamoeba histolytica thymidine kinase, putative 0.0148 0.0037 0.0881
Loa Loa (eye worm) galactosyltransferase 0.01 0.0025 0.0586
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0001 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.0071 0.116
Schistosoma mansoni hypothetical protein 0.0278 0.0071 0.1688
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0006 0 0.0002
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0029
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0156 0.0039 0.0934
Loa Loa (eye worm) galactosyltransferase 0.0026 0.0005 0.0129
Onchocerca volvulus 0.0278 0.0071 0.1449
Entamoeba histolytica MIR domain protein 0.0008 0.0001 0.0014
Mycobacterium tuberculosis Hypothetical protein 0.0174 0.0044 0.0044
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0009 0.0001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Mycobacterium leprae AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE) 0.0043 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.0071 0.1688
Echinococcus multilocularis fmrfamide receptor 0.0278 0.0071 0.116
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.001 0.0001 0.0029
Brugia malayi DNA polymerase delta catalytic subunit 0.0009 0.0001 0.0022
Plasmodium vivax orotidine 5'-phosphate decarboxylase, putative 0.0536 0.0138 0.3287
Chlamydia trachomatis hypothetical protein 0.0019 0.0004 0.0009
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0009 0.0001 0.0022
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0003 0.0076
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.001 0.0001 0.003
Brugia malayi hypothetical protein 0.0012 0.0002 0.0039
Echinococcus multilocularis synaptojanin 1 0.001 0.0001 0.002
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0234 0.0059 0.1414
Schistosoma mansoni adenosylhomocysteinase 0.0097 0.0024 0.0565
Schistosoma mansoni adenoreceptor 0.0278 0.0071 0.1688
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.001 0.0001 0.0029
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0032 0.0007 0.0167
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.001 0.0001 0.0029
Trichomonas vaginalis thymidine kinase, putative 0.0148 0.0037 0.0882
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0278 0.0071 0.116
Plasmodium vivax importin-beta 2, putative 0.0022 0.0004 0.0102
Plasmodium falciparum DNA polymerase alpha catalytic subunit A 0.0009 0.0001 0.0023
Echinococcus granulosus beta-adrenergic receptor kinase 0.0012 0.0002 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.0071 0.116
Brugia malayi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.1621 0.0418 1
Trypanosoma cruzi cytidine deaminase-like protein, putative 0.0065 0.0015 0.0368
Schistosoma mansoni neuropeptide receptor 0.0278 0.0071 0.1688
Schistosoma mansoni biogenic amine (5HT) receptor 0.0278 0.0071 0.1688
Entamoeba histolytica phosphofructokinase, putative 0.0079 0.0019 0.0457
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0025
Entamoeba histolytica DNA polymerase alpha catalytic subunit, putative 0.0009 0.0001 0.0023
Treponema pallidum phosphoribosylpyrophosphate synthetase 0.0043 0.001 0.0026
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.1621 0.0418 1
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.0145 0.0036 0.0036
Toxoplasma gondii exonuclease III APE 0.005 0.0012 0.0276
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0003 0.0076
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0156 0.0039 0.0039
Echinococcus multilocularis expressed protein 0.0227 0.0058 0.0944
Echinococcus multilocularis sodium:nucleoside cotransporter 2 0.0271 0.0069 0.1128
Brugia malayi Dopamine receptor protein 1 0.0278 0.0071 0.1688
Schistosoma mansoni biogenic amine (5HT) receptor 0.0278 0.0071 0.1688
Echinococcus multilocularis lamin 0.0018 0.0003 0.0052
Echinococcus multilocularis serotonin receptor 0.0278 0.0071 0.116
Echinococcus multilocularis sex peptide receptor 0.0278 0.0071 0.116
Plasmodium falciparum UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.1621 0.0418 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0102
Mycobacterium ulcerans orotate phosphoribosyltransferase 0.0188 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0017
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0003 0.0076
Onchocerca volvulus 0.0043 0.001 0.0201
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0012 0.0002 0.0039
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0001 0.0029
Echinococcus multilocularis dro:myosuppressin receptor 0.0278 0.0071 0.116
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0012 0.0002 0.0043
Entamoeba histolytica recQ family helicase, putative 0.0008 0.0001 0.0013
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0003 0.0052
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0278 0.0071 0.1688
Echinococcus granulosus biogenic amine 5HT receptor 0.0278 0.0071 0.1688
Echinococcus granulosus uridine 5' monophosphate synthase 0.058 0.0149 0.3554
Echinococcus granulosus regulator of G protein signaling 3 0.0012 0.0002 0.0039
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0007 0 0.0007
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0009 0.0001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0204
Onchocerca volvulus 0.001 0.0001 0.0022
Brugia malayi 6-phosphofructokinase 0.0079 0.0019 0.0457
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.0071 0.1688
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Giardia lamblia O-linked GlcNAc transferase 0.0029 0.0006 0.0144
Brugia malayi hypothetical protein 0.0174 0.0044 0.1047
Echinococcus multilocularis smad 0.0019 0.0004 0.0059
Trichomonas vaginalis apoptosis inducing factor, putative 0.0005 0.000003751 0.0001
Loa Loa (eye worm) MH2 domain-containing protein 0.0284 0.0072 0.1723
Echinococcus multilocularis adenine phosphoribosyltransferase 0.0043 0.001 0.0161
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0004 0.0004
Brugia malayi Globin family protein 0.001 0.0001 0.0025
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Brugia malayi Cytochrome P450 family protein 0.0012 0.0002 0.0043
Entamoeba histolytica hypothetical protein 0.0094 0.0023 0.0549
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0191
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0009 0.0001 0.0022
Leishmania major endonuclease/exonuclease protein-like protein 0.001 0.0001 0.0029
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.001 0.0001 0.003
Onchocerca volvulus 0.001 0.0001 0.0025
Schistosoma mansoni cpg binding protein 0.0025 0.0005 0.0119
Leishmania major GTP-binding protein, putative 0.0016 0.0003 0.0066
Schistosoma mansoni dihydrofolate reductase 0.0395 0.0101 0.2413
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.001 0.0001 0.0029
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0004 0.0093
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Brugia malayi Adenine phosphoribosyltransferase 0.0043 0.001 0.0234
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0019 0.0004 0.0086
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0211 0.0053 0.1275
Loa Loa (eye worm) hypothetical protein 0.017 0.0043 0.1018
Entamoeba histolytica hypothetical protein 0.0018 0.0003 0.0076
Echinococcus multilocularis axis inhibition protein axin 0.0012 0.0002 0.0027
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0005 0.000003751 0.0001
Entamoeba histolytica phosphofructokinase, putative 0.0079 0.0019 0.0457
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.011 0.0027 0.0646
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Leishmania major RNA-editing complex protein MP100, putative 0.001 0.0001 0.0029
Echinococcus multilocularis fmrfamide receptor 0.0278 0.0071 0.116
Echinococcus granulosus allatostatin A receptor 0.0278 0.0071 0.1688
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0156 0.0039 0.0934
Trypanosoma brucei orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.058 0.0149 0.3554
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0059 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0076
Onchocerca volvulus 0.0278 0.0071 0.1449
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.001 0.0001 0.003
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0012 0.0002 0.0039
Schistosoma mansoni beta-14-galactosyltransferase 0.0026 0.0005 0.0129
Onchocerca volvulus 0.0278 0.0071 0.1449
Brugia malayi Cytochrome P450 family protein 0.0012 0.0002 0.0043
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.001 0.0001 0.0025
Loa Loa (eye worm) cytochrome P450 0.0007 0 0.0007
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0156 0.0039 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0004 0.01
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Brugia malayi hypothetical protein 0.0057 0.0013 0.0319
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0004 0.0093
Echinococcus granulosus stromal cell derived factor 2 0.0008 0.0001 0.0014
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0577 0.0148 0.3538
Loa Loa (eye worm) RGS-3 protein 0.0012 0.0002 0.0039
Giardia lamblia Guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Treponema pallidum hypothetical protein 0.0043 0.001 0.0026
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0156 0.0039 0.0933
Echinococcus multilocularis beta adrenergic receptor kinase 0.0012 0.0002 0.0029
Echinococcus granulosus sex peptide receptor 0.0278 0.0071 0.1688
Echinococcus granulosus g protein coupled receptor 0.0278 0.0071 0.1688
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0278 0.0071 0.116
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0009 0.0001 0.0015
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0004 0.0093
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0007 0 0.0007
Echinococcus granulosus O glycosyltransferase 0.0049 0.0011 0.0272
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Echinococcus granulosus GPCR family 2 0.0018 0.0003 0.0076
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0009 0.0001 0.0023
Schistosoma mansoni smad 0.0009 0.0001 0.002
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0278 0.0071 0.116
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0043 0.001 0.0234
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.011 0.0027 0.0646
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0278 0.0071 0.1449
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0001 0.0029
Echinococcus granulosus polypeptide N acetylgalactosaminyltransferase 0.0011 0.0001 0.0033
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0012 0.0002 0.0043
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0021 0.0004 0.0011
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0009 0.0001 0.0022
Schistosoma mansoni importin beta-1 0.0022 0.0004 0.0102
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0017
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trichomonas vaginalis DNA polymerase II, putative 0.0014 0.0002 0.0055
Entamoeba histolytica hypothetical protein 0.0211 0.0053 0.1275
Loa Loa (eye worm) adenosylhomocysteinase 0.0156 0.0039 0.0933
Echinococcus granulosus concentrative Na nucleoside cotransporter 0.0415 0.0106 0.2535
Schistosoma mansoni cpg binding protein 0.0023 0.0005 0.0111
Schistosoma mansoni myoglobin 1 0.001 0.0001 0.0025
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0014 0.0002 0.0055
Echinococcus multilocularis regulator of G protein signaling 7 0.0012 0.0002 0.0027
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0009 0.0001 0.0015
Echinococcus granulosus Smad4 0.0019 0.0004 0.0086
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Echinococcus granulosus cpg binding protein 0.0025 0.0005 0.0119
Brugia malayi phosphofructokinase 0.0079 0.0019 0.0457
Echinococcus granulosus 7TM GPCR rhodopsin 0.0278 0.0071 0.1688
Echinococcus multilocularis somatostatin receptor 0.0278 0.0071 0.116
Loa Loa (eye worm) hypothetical protein 0.0057 0.0013 0.0319
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0036
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0006 0 0.0002
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0004 0.0093
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0002
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Plasmodium vivax exodeoxyribonuclease III, putative 0.001 0.0001 0.0029
Brugia malayi Phosphoribosyl transferase domain containing protein 0.0043 0.001 0.0234
Trichomonas vaginalis importin beta-1, putative 0.0018 0.0003 0.0077
Brugia malayi Deoxynucleoside kinase family protein 0.0211 0.0053 0.1275
Schistosoma mansoni ran 0.0016 0.0003 0.0066
Trypanosoma cruzi PAB1-binding protein , putative 0.0057 0.0013 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.0053 0.1276
Schistosoma mansoni nocturnin 0.001 0.0001 0.0029
Brugia malayi cation channel family protein 0.0076 0.0018 0.0436
Echinococcus granulosus NADH ubiquinone oxidoreductase 42 kDa subunit 0.0211 0.0053 0.1275
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.005 0.0012 0.0276
Plasmodium falciparum thioredoxin reductase 0.0059 0.0014 0.0333
Onchocerca volvulus 0.001 0.0001 0.0022
Entamoeba histolytica hypothetical protein 0.0211 0.0053 0.1275
Echinococcus granulosus neuropeptide receptor 0.0278 0.0071 0.1688
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.011 0.0027 0.0646
Schistosoma mansoni opsin-like receptor 0.0278 0.0071 0.1688
Brugia malayi DNA polymerase alpha catalytic subunit 0.0026 0.0005 0.0129
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0016 0.0003 0.0066
Onchocerca volvulus 0.001 0.0001 0.0022
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0003 0.0076
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0009 0.0001 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.0071 0.116
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0003 0.0076
Echinococcus granulosus cytidine deaminase 0.0065 0.0015 0.0368
Leishmania major protein kinase, putative,eukaryotic translation initiation factor 2-alpha kinase precursor, putative 0.0142 0.0035 0.0847
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.005 0.0012 0.0012
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.005 0.0012 0.019
Schistosoma mansoni hypothetical protein 0.0007 0 0.0007
Schistosoma mansoni regulator of G protein signaling 0.0012 0.0002 0.0039
Brugia malayi sulfakinin receptor protein 0.0278 0.0071 0.1688
Echinococcus multilocularis deoxyribonuclease 1 2 0.001 0.0001 0.002
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Schistosoma mansoni intermediate filament proteins 0.0018 0.0003 0.0076
Schistosoma mansoni histamine h1 receptor 0.0278 0.0071 0.1688
Trichomonas vaginalis glucosaminephosphotransferase, putative 0.1621 0.0418 1
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Echinococcus granulosus axis inhibition protein axin 0.0012 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0005 0.00000000000061919 0.000000000014796
Echinococcus granulosus adenosylhomocysteinase 0.0156 0.0039 0.0933
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0004 0.0093
Mycobacterium tuberculosis Probable pyrimidine operon regulatory protein PyrR 0.0043 0.001 0.001
Giardia lamblia hypothetical protein 0.001 0.0001 0.0029
Trichomonas vaginalis glutamate synthase, putative 0.0005 0.000003751 0.0001
Echinococcus granulosus regulator of G protein signaling 3 0.0012 0.0002 0.0039
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0007 0 0.0007
Schistosoma mansoni inositol 145-trisphosphate receptor 0.004 0.0009 0.0216
Plasmodium vivax N-acetylglucosamine-1-phosphate transferase, putative 0.1621 0.0418 1
Schistosoma mansoni 6-phosphofructokinase 0.0079 0.0019 0.0457
Schistosoma mansoni regulator of G protein signaling 0.0012 0.0002 0.0039
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0278 0.0071 0.116
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0004 0.0093
Brugia malayi MH1 domain containing protein 0.0011 0.0001 0.0033
Mycobacterium tuberculosis Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 3.8606 1 1
Echinococcus granulosus dro:myosuppressin receptor 0.0278 0.0071 0.1688
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.0071 0.116
Giardia lamblia DNA polymerase alpha subunit A 0.0027 0.0006 0.0136
Brugia malayi RNA, U transporter 1 0.0062 0.0015 0.0352
Trypanosoma brucei eukaryotic translation initiation factor 2-alpha kinase 2 0.0142 0.0035 0.0847
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0003 0.0052
Echinococcus multilocularis Metazoa galactosyltransferase 0.0085 0.0021 0.0337
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.001 0.0001 0.002
Echinococcus granulosus neutral sphingomyelinase 0.001 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0278 0.0071 0.1688
Leishmania major hypothetical protein, conserved 0.001 0.0001 0.0029
Echinococcus granulosus serotonin receptor 0.0278 0.0071 0.1688
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0009 0.0001 0.0022
Schistosoma mansoni alpha-1 adrenergic receptor 0.0278 0.0071 0.1688
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0044 0.1047
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0278 0.0071 0.116
Leishmania major cytochrome p450-like protein 0.0012 0.0002 0.0043
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0536 0.0138 0.3287
Brugia malayi putative neuropeptide receptor NPR1 0.0278 0.0071 0.1688
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0012 0.0002 0.0039
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0004 0.0086
Schistosoma mansoni synaptojanin 0.001 0.0001 0.0029
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0005 0.000003751 0.0001
Echinococcus granulosus thioredoxin glutathione reductase 0.0059 0.0014 0.0333
Chlamydia trachomatis phospho-N-acetylmuramoyl-pentapeptide-transferase 1.4674 0.38 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0003 0.006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0039
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0156 0.0039 0.0933
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0005 0.000003751 0.0001
Loa Loa (eye worm) hypothetical protein 0.1621 0.0418 1
Brugia malayi neuropeptide F receptor 0.0278 0.0071 0.1688
Giardia lamblia DNA polymerase delta, catalytic subunit 0.0009 0.0001 0.0022
Trypanosoma brucei RNA helicase, putative 0.0108 0.0027 0.0637
Leishmania major ATP-dependent phosphofructokinase 0.0079 0.0019 0.0457
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Trichomonas vaginalis DNA helicase recq1, putative 0.0014 0.0002 0.0054
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0016 0.0003 0.0066
Echinococcus multilocularis allatostatin A receptor 0.0278 0.0071 0.116
Schistosoma mansoni smad1 5 8 and 0.0019 0.0004 0.0086
Onchocerca volvulus 0.1888 0.0488 1
Entamoeba histolytica hypothetical protein 0.0211 0.0053 0.1275
Onchocerca volvulus 0.0278 0.0071 0.1449
Brugia malayi Adenosylhomocysteinase 0.0156 0.0039 0.0933
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0004 0.0093
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0005 0.00000000000061919 0.000000000014796
Loa Loa (eye worm) 6-phosphofructokinase 0.0079 0.0019 0.0457
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0004 0.0099
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0042 0.0009 0.0225
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0013 0.0313
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0004 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0002 0.0043
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0025
Echinococcus granulosus expressed protein 0.0227 0.0058 0.1374
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0043 0.001 0.0234
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0278 0.0071 0.1688
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0012 0.0002 0.0043
Onchocerca volvulus 0.001 0.0001 0.0022
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0009 0.0001 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.0053 0.1276
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0043 0.001 0.0234
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0006 0 0.0002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0278 0.0071 0.1688
Trichomonas vaginalis DNA helicase recq, putative 0.0008 0.0001 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.0071 0.1688
Giardia lamblia DNA polymerase epsilon, catalytic subunit 0.0009 0.0001 0.0022
Brugia malayi Bloom's syndrome protein homolog 0.0014 0.0002 0.0053
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.1621 0.0418 1
Echinococcus multilocularis O glycosyltransferase 0.0049 0.0011 0.0187
Plasmodium vivax serine/threonine protein kinase, putative 0.0142 0.0035 0.0847
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0016 0.0003 0.0066
Echinococcus multilocularis beta 1,4 galactosyltransferase 7 0.0026 0.0005 0.0089
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0009 0.0001 0.0022
Brugia malayi Serotonin receptor 0.0278 0.0071 0.1688
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0004 0.0093
Schistosoma mansoni adenosylhomocysteinase 0.0097 0.0024 0.0565
Onchocerca volvulus Globin homolog 0.001 0.0001 0.0022
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0009 0.0001 0.0022
Brugia malayi Smad1 0.0019 0.0004 0.0086
Echinococcus multilocularis regulator of G protein signaling 0.0012 0.0002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0039
Echinococcus granulosus GTP binding nuclear protein Ran 0.0016 0.0003 0.0066
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0009 0.0001 0.0019
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0395 0.0101 0.0101
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0004 0.0093
Wolbachia endosymbiont of Brugia malayi hypothetical protein 0.0019 0.0004 0.0004
Onchocerca volvulus 0.0018 0.0003 0.0065
Schistosoma mansoni phenylalanine decarboxylase 0.0026 0.0005 0.0129
Echinococcus multilocularis Metazoa galactosyltransferase 0.01 0.0025 0.0403
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0004 0.001
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0008 0.0001 0.0013
Schistosoma mansoni hypothetical protein 0.0767 0.0197 0.4714
Loa Loa (eye worm) thioredoxin reductase 0.0059 0.0014 0.0333
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0009 0.0001 0.0022
Leishmania major hypothetical protein, conserved 0.0028 0.0006 0.0142
Echinococcus multilocularis musashi 0.0018 0.0003 0.0052
Echinococcus granulosus g protein coupled receptor 0.0278 0.0071 0.1688
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Echinococcus granulosus thymidine kinase 0.1593 0.0411 0.9827
Mycobacterium tuberculosis Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) 0.0043 0.001 0.001
Trypanosoma brucei thymidine kinase 0.0148 0.0037 0.0881
Trypanosoma cruzi cytidine deaminase-like protein 0.0065 0.0015 0.0368
Echinococcus multilocularis traf and tnf receptor associated protein 0.001 0.0001 0.002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0001 0.0008
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0003 0.0052
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.011 0.0027 0.0646
Brugia malayi Galactosyltransferase family protein 0.01 0.0025 0.0586
Brugia malayi MH2 domain containing protein 0.0009 0.0001 0.002
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0004 0.0093
Echinococcus multilocularis mothers against decapentaplegic 6 0.0009 0.0001 0.0014
Echinococcus multilocularis 0.0007 0 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.011 0.0027 0.0646
Schistosoma mansoni smad1 5 8 and 0.0019 0.0004 0.0086
Toxoplasma gondii DNA polymerase family B protein 0.0009 0.0001 0.0022
Giardia lamblia Hypothetical protein 0.0211 0.0053 0.1275
Onchocerca volvulus 0.0278 0.0071 0.1449
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0278 0.0071 0.1688
Leishmania major orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative 0.058 0.0149 0.3554
Echinococcus multilocularis thioredoxin glutathione reductase 0.0059 0.0014 0.0228
Echinococcus granulosus regulator of G protein signaling 7 0.0012 0.0002 0.0039
Entamoeba histolytica cytidine deaminase, putative 0.0065 0.0015 0.0368
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0004 0.01
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0001 0.0029
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0278 0.0071 0.1688
Brugia malayi hypothetical protein 0.0278 0.0071 0.1688
Brugia malayi thymidylate synthase 0.0367 0.0094 0.2237
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0278 0.0071 0.116
Echinococcus granulosus biogenic amine 5HT receptor 0.0278 0.0071 0.1688
Onchocerca volvulus 0.0278 0.0071 0.1449
Loa Loa (eye worm) Smad1 0.0019 0.0004 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0039
Loa Loa (eye worm) UDP-Galactose:b-N-acetylglucosamine b1,4-galactosyltransferase 4 0.0026 0.0005 0.0129
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trypanosoma cruzi thymidine kinase, putative 0.0148 0.0037 0.0881
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0278 0.0071 0.1688
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0002 0.0043
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0009 0.0001 0.0022
Echinococcus multilocularis neuropeptides capa receptor 0.0278 0.0071 0.116
Brugia malayi Dihydrofolate reductase 0.0395 0.0101 0.2413
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.005 0.0012 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0039
Treponema pallidum phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) 1.4674 0.38 1
Entamoeba histolytica hypothetical protein 0.0211 0.0053 0.1275
Trichomonas vaginalis ap endonuclease, putative 0.005 0.0012 0.0277
Loa Loa (eye worm) dihydrofolate reductase 0.0395 0.0101 0.2413
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0003 0.0076
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0003 0.0076
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0577 0.0148 0.3538
Toxoplasma gondii orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase 0.0536 0.0138 0.3287
Plasmodium vivax thioredoxin reductase, putative 0.0059 0.0014 0.0333
Entamoeba histolytica adenosylhomocysteinase, putative 0.0156 0.0039 0.0933
Schistosoma mansoni beta-14-galactosyltransferase 34-related 0.0026 0.0005 0.0129
Brugia malayi GnHR receptor homolog 0.0278 0.0071 0.1688
Echinococcus granulosus neuropeptide receptor 0.0278 0.0071 0.1688
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Toxoplasma gondii hypothetical protein 0.0026 0.0005 0.0129
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0001 0.0029
Mycobacterium leprae PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) 0.0188 0.0047 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.0071 0.116
Trichomonas vaginalis cytidine deaminase, putative 0.0065 0.0015 0.0368
Echinococcus multilocularis neuropeptide receptor 0.0278 0.0071 0.116
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0001 0.0029
Entamoeba histolytica hypothetical protein 0.0211 0.0053 0.1275
Toxoplasma gondii orotate phosphoribosyltransferase 0.0188 0.0047 0.1129
Echinococcus multilocularis neuropeptide receptor 0.0278 0.0071 0.116
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0032 0.0007 0.0115
Echinococcus granulosus importin subunit beta 1 0.0022 0.0004 0.0102
Echinococcus multilocularis solute carrier family 28 0.0415 0.0106 0.1742
Echinococcus granulosus Regulator of G protein signaling 20 0.0012 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0278 0.0071 0.1688
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0005 0.000003751 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0006 0 0.0002
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0006 0 0.0002
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0 0.0007
Echinococcus granulosus neuropeptide Y receptor 0.0278 0.0071 0.1688
Wolbachia endosymbiont of Brugia malayi hypothetical protein 0.0019 0.0004 0.0004
Schistosoma mansoni myosin xvIII 0.0278 0.0071 0.1688
Giardia lamblia Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative 0.0211 0.0053 0.1275
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0039
Brugia malayi F/Y-rich N-terminus family protein 0.0007 0 0.0011
Echinococcus multilocularis bloom syndrome protein 0.0014 0.0002 0.0037
Loa Loa (eye worm) globin family protein 0.001 0.0001 0.0025
Entamoeba histolytica sphingomyelinase C precursor, putative 0.001 0.0001 0.0029
Trypanosoma brucei importin beta-1 subunit, putative 0.0022 0.0004 0.0102
Echinococcus multilocularis ryanodine receptor 44f 0.0035 0.0008 0.0128
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0003 0.006
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.001 0.0001 0.003
Echinococcus granulosus regulator of G protein signaling 7 0.0012 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0039
Schistosoma mansoni thymidine kinase 0.1593 0.0411 0.9827
Brugia malayi G-protein coupled receptor 0.0278 0.0071 0.1688
Trypanosoma cruzi mitochondrial protein 99, putative 0.001 0.0001 0.0029
Echinococcus granulosus lamin 0.0018 0.0003 0.0076
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0278 0.0071 0.1688
Brugia malayi cytochrome P450 0.0007 0 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.0071 0.1688
Brugia malayi Importin beta-1 subunit 0.0022 0.0004 0.0102
Echinococcus multilocularis cytidine deaminase 0.0065 0.0015 0.0253
Wolbachia endosymbiont of Brugia malayi amidophosphoribosyltransferase 0.0043 0.001 0.001
Brugia malayi CXXC zinc finger family protein 0.0023 0.0005 0.0111
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0278 0.0071 0.1688
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.0211 0.0053 0.1275
Loa Loa (eye worm) phosphofructokinase 0.0079 0.0019 0.0457

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.005 uM Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysis ChEMBL. 25022879
IC50 (binding) = 0.005 uM Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysis ChEMBL. 26037610
Ki (binding) = 1.5 nM Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by Lineweaver-Burk plot ChEMBL. 25022879

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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