Detailed information for compound 999080

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 213.23 | Formula: C10H15NO4
  • H donors: 2 H acceptors: 3 LogP: 0.7 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC([C@@H]([C@@]12NC(=O)[C@@H]([C@@H]2OC1=O)C)O)C
  • InChi: 1S/C10H15NO4/c1-4(2)6(12)10-7(15-9(10)14)5(3)8(13)11-10/h4-7,12H,1-3H3,(H,11,13)/t5-,6+,7+,10+/m1/s1
  • InChiKey: FWPWHHUJACGNMZ-NUMRIWBASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0331 0.1324
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.0063 0.0507
Echinococcus granulosus cyclins 0.0215 0.1091 0.1091
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.1882 1 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0072 0.0277
Echinococcus multilocularis cyclin y 0.0052 0.0218 0.0218
Trichomonas vaginalis cyclins, putative 0.0215 0.1091 0.4383
Brugia malayi MBOAT family protein 0.0227 0.1156 0.1156
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0034 0.0124 0.0686
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0024 0.0083
Trypanosoma cruzi CYC2-like cyclin, putative 0.0215 0.1091 0.6153
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0063 0.0506
Trypanosoma cruzi hypothetical protein, conserved 0.0052 0.0218 0.1217
Echinococcus granulosus chromobox protein 1 0.0059 0.0255 0.0255
Echinococcus multilocularis cyclin B3 1 0.0215 0.1091 0.1091
Schistosoma mansoni transcription factor LCR-F1 0.0099 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0049 0.0203 0.0203
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0331 0.0331
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0024 0.0024
Brugia malayi Cytochrome P450 family protein 0.0068 0.0306 0.0306
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0331 0.0458
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0375 0.0375
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0053 0.0053
Loa Loa (eye worm) heterochromatin protein 1 0.0059 0.0255 0.0255
Schistosoma mansoni cyclin k 0.0052 0.0218 0.0218
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0012 0.0003 0.0003
Leishmania major DNA polymerase eta, putative 0.003 0.01 0.0552
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.0063 0.0246
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0059 0.0258 0.0258
Brugia malayi CHD4 protein 0.0012 0.0002 0.0002
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0049 0.0203 0.0203
Trichomonas vaginalis cyclin B, putative 0.0215 0.1091 0.4383
Loa Loa (eye worm) hypothetical protein 0.0073 0.0331 0.0331
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0023 0.0063 0.0246
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0533 0.0533
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0227 0.1156 0.1156
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0049 0.0203 0.0203
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0002 0.0002
Toxoplasma gondii cyclin dependent kinase binding protein 0.0052 0.0218 0.03
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0053 0.0053
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0024 0.0024
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0028 0.0035
Echinococcus multilocularis cyclin y 0.0052 0.0218 0.0218
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0021 0.0052 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0053 0.0053
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0073 0.0329 0.1337
Echinococcus granulosus sterol O acyltransferase 1 0.0227 0.1156 0.1156
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0072 0.0072
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0012 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.0063 0.0507
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0174 0.0871 0.0871
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0162 0.0807 0.4546
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0227 0.1156 0.1156
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0053 0.0053
Schistosoma mansoni Cyclin fold protein 0.0052 0.0218 0.0218
Trichomonas vaginalis porcupine, putative 0.0227 0.1156 0.4647
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.019 0.0954 0.8245
Trichomonas vaginalis esterase, putative 0.0073 0.0331 0.1324
Loa Loa (eye worm) hypothetical protein 0.0059 0.0258 0.0258
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.1145 0.1145
Schistosoma mansoni cyclins 0.0215 0.1091 0.1091
Echinococcus granulosus cyclin B 0.0215 0.1091 0.1091
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0053 0.0053
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0012 0.0003 0.0003
Trypanosoma cruzi cyclin, putative 0.0215 0.1091 0.6153
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0053 0.0053
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0029 0.0037
Loa Loa (eye worm) hypothetical protein 0.0038 0.0141 0.0141
Onchocerca volvulus 0.0026 0.0079 0.0657
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0272 0.0272
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.1354 0.7176 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.001 0.0043
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0063 1
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0227 0.1156 0.1156
Schistosoma mansoni cyclin l 0.0052 0.0218 0.0218
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0072 0.0277
Plasmodium vivax cyclin 4, putative 0.0052 0.0218 0.03
Echinococcus multilocularis GPCR, family 2 0.0059 0.0258 0.0258
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0012 0.0003 0.0003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0063 0.0339
Echinococcus multilocularis microtubule associated protein 2 0.0625 0.3281 0.3281
Toxoplasma gondii aldehyde dehydrogenase 0.0101 0.048 0.0665
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0045 0.0045
Schistosoma mansoni DNA polymerase eta 0.0054 0.0227 0.0227
Schistosoma mansoni hypothetical protein 0.0128 0.0627 0.0627
Echinococcus multilocularis Cyclin L1 0.0052 0.0218 0.0218
Leishmania major trypanothione reductase 0.0029 0.0093 0.0512
Schistosoma mansoni sterol O-acyltransferase 1 0.0227 0.1156 0.1156
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0065 0.029 0.2428
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.1354 0.7176 1
Mycobacterium ulcerans DNA polymerase IV 0.0034 0.0124 0.1027
Onchocerca volvulus 0.0215 0.1091 0.9432
Loa Loa (eye worm) cyclin domain-containing protein 0.0215 0.1091 0.1091
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0063 0.0276 0.0276
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0052 0.0052
Loa Loa (eye worm) cyclin domain-containing protein 0.0052 0.0218 0.0218
Brugia malayi Bromodomain containing protein 0.0041 0.016 0.016
Brugia malayi nuclear receptor NHR-88 0.0021 0.0053 0.0053
Trypanosoma brucei mitotic cyclin 6 0.0215 0.1091 0.6153
Schistosoma mansoni microtubule-associated protein tau 0.0625 0.3281 0.3281
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0101 0.048 0.048
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0012 0.0003 0.0003
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0063 0.0083
Echinococcus granulosus thioredoxin glutathione reductase 0.0029 0.0095 0.0095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0053 0.0053
Trypanosoma brucei cyclin 3 0.0052 0.0218 0.1217
Echinococcus multilocularis dna polymerase eta 0.0054 0.0227 0.0227
Echinococcus multilocularis cyclin B 0.0215 0.1091 0.1091
Loa Loa (eye worm) MBCTL1 0.0049 0.0203 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0227 0.1156 0.4647
Onchocerca volvulus 0.0073 0.0331 0.2849
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0053 0.0053
Loa Loa (eye worm) thioredoxin reductase 0.0029 0.0093 0.0093
Brugia malayi MBOAT family protein 0.0227 0.1156 0.1156
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0053 0.0053
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0044 0.0044
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0045 0.0045
Onchocerca volvulus Cyclin L homolog 0.0052 0.0218 0.1865
Mycobacterium tuberculosis Probable oxidoreductase 0.0073 0.0329 0.1337
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0063 0.0083
Trypanosoma brucei unspecified product 0.0024 0.0067 0.0363
Brugia malayi Cytochrome P450 family protein 0.0023 0.0063 0.0063
Entamoeba histolytica hypothetical protein 0.0052 0.0218 0.0838
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0016 0.0024 0.0024
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0227 0.1156 0.1156
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.0063 0.0246
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0012 0.0003 0.0003
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0053 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0053 0.0053
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.0063 0.0507
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0059 0.0258 0.0258
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.0063 0.0246
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0188 0.0944 0.0944
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0149 0.0561
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0029 0.0029
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.0063 0.0507
Entamoeba histolytica hypothetical protein 0.0099 0.0472 0.1865
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0181 0.0717
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0476 0.2486 1
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0267 0.1365 0.1365
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0024 0.0083
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0099 0.0472 0.0472
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0694 0.0694
Onchocerca volvulus 0.0073 0.0331 0.2849
Echinococcus granulosus cyclin t1 0.0052 0.0218 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0227 0.1156 0.4647
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0215 0.1091 0.1091
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.0063 0.0246
Onchocerca volvulus 0.0043 0.0171 0.146
Schistosoma mansoni ap endonuclease 0.002 0.0045 0.0045
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0227 0.1156 0.1156
Entamoeba histolytica hypothetical protein 0.0023 0.0063 0.0211
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0331 0.1324
Entamoeba histolytica cyclin, domain containing protein 0.0052 0.0218 0.0838
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0053 0.0053
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0012 0.0003 0.0003
Trichomonas vaginalis cyclin B, putative 0.0215 0.1091 0.4383
Treponema pallidum alginate O-acetylation protein (algI) 0.0227 0.1156 0.4647
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0227 0.1156 0.1156
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0012 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0533 0.0533
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0233 0.1184 0.4846
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0034 0.0124 0.0124
Brugia malayi Thioredoxin reductase 0.0029 0.0093 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0053 0.0053
Brugia malayi Cyclin, N-terminal domain containing protein 0.0052 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0053
Trichomonas vaginalis cyclins, putative 0.0215 0.1091 0.4383
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0053 0.0053
Brugia malayi Calcitonin receptor-like protein seb-1 0.0188 0.0944 0.0944
Leishmania major cytochrome p450-like protein 0.0023 0.0063 0.0339
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0052 0.0218 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0065 0.0251
Brugia malayi Cyclin, N-terminal domain containing protein 0.0215 0.1091 0.1091
Leishmania major glycerol uptake protein, putative 0.0227 0.1156 0.6524
Brugia malayi diacylglycerol acyltransferase 0.1354 0.7176 0.7176
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0063 0.0339
Entamoeba histolytica hypothetical protein 0.0227 0.1156 0.463
Loa Loa (eye worm) hypothetical protein 0.0054 0.0227 0.0227
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0059 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0053
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0034 0.0124 0.0124
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.0063 0.0246
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0063 0.0063
Echinococcus multilocularis expressed conserved protein 0.0012 0.0003 0.0003
Brugia malayi Cyclin, N-terminal domain containing protein 0.0052 0.0218 0.0218
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0063 0.0338
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0065 0.029 0.1177
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.0063 0.0339
Echinococcus multilocularis cyclin G2 0.0052 0.0218 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0053 0.0053
Trypanosoma brucei ISWI complex protein 0.0015 0.002 0.0099
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0331 0.2783
Brugia malayi RNA recognition motif domain containing protein 0.0111 0.0533 0.0533
Leishmania major cytochrome p450-like protein 0.0023 0.0063 0.0339
Onchocerca volvulus 0.0227 0.1156 1
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0012 0.0003 0.0003
Brugia malayi Cyclic-nucleotide gated cation channel 0.0016 0.0024 0.0024
Echinococcus multilocularis chromobox protein 1 0.0059 0.0255 0.0255
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.001 0.0043
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0053 0.0438
Entamoeba histolytica cyclin, domain containing protein 0.0052 0.0218 0.0838
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0342 0.1771 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0067 0.0363
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0034 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0073 0.0331 0.0331
Onchocerca volvulus 0.0052 0.0218 0.1865
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0227 0.1156 0.1156
Trichomonas vaginalis cyclins, putative 0.0052 0.0218 0.0867
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.0003 0.0003
Echinococcus granulosus cyclin B3 1 0.0215 0.1091 0.1091
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0063 0.0245
Brugia malayi Cyclin, N-terminal domain containing protein 0.0052 0.0218 0.0218
Brugia malayi nuclear hormone receptor 0.0021 0.0053 0.0053
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0024 0.0024
Echinococcus granulosus Cyclin L1 0.0052 0.0218 0.0218
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0149 0.0204
Echinococcus granulosus cGMP dependent protein kinase 0.0012 0.0003 0.0003
Brugia malayi Cyclin C 0.0052 0.0218 0.0218
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0063 0.0083
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0052 0.0218 0.03
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0023 0.0063 0.0339
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0331 0.0331
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0065 0.029 0.1177
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.0063 0.0507
Trypanosoma brucei unspecified product 0.0024 0.0067 0.0363
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.0063 0.0507
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0255 0.1015
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.0063 0.0246
Onchocerca volvulus Protein CNPPD1 homolog 0.0052 0.0218 0.1865
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0227 0.1156 0.1156
Trichomonas vaginalis cyclin B3, putative 0.0052 0.0218 0.0867
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0012 0.0003 0.0003
Echinococcus granulosus cGMP dependent protein kinase 1 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0053
Brugia malayi cyclin fold protein 1 variant b 0.0052 0.0218 0.0218
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0225 0.1145 0.1145
Giardia lamblia Hypothetical protein 0.0052 0.0218 0.0867
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0181 0.0248
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0052 0.0218 0.03
Brugia malayi chromobox protein homolog 3 0.0033 0.0117 0.0117
Plasmodium vivax glutathione reductase, putative 0.0029 0.0093 0.0126
Echinococcus multilocularis 0.0023 0.0063 0.0063
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0053 0.0053
Trypanosoma cruzi cyclin 6, putative 0.0215 0.1091 0.6153
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0053 0.0053
Giardia lamblia DINP protein human, muc B family 0.0034 0.0124 0.0488
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0053 0.0053
Schistosoma mansoni cyclin B3 0.0215 0.1091 0.1091
Schistosoma mansoni hypothetical protein 0.0059 0.0258 0.0258
Echinococcus granulosus GPCR family 2 0.0059 0.0258 0.0258
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.0063 0.0246
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0227 0.1156 0.463
Loa Loa (eye worm) hypothetical protein 0.0081 0.0375 0.0375
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0063 0.0338
Trichomonas vaginalis cyclin B, putative 0.0215 0.1091 0.4383
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0111 0.0533 0.0533
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0225 0.1145 0.1145
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0227 0.1156 0.1156
Schistosoma mansoni hypothetical protein 0.0518 0.2708 0.2708
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0024 0.0024
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0188 0.0944 0.0944
Echinococcus multilocularis voltage gated potassium channel 0.0021 0.0052 0.0052
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0063 0.0339
Loa Loa (eye worm) mbt repeat family protein 0.0043 0.0171 0.0171
Toxoplasma gondii cyclin 4, putative 0.0052 0.0218 0.03
Mycobacterium tuberculosis Probable dehydrogenase 0.0065 0.029 0.1177
Echinococcus multilocularis cyclins 0.0215 0.1091 0.1091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0053 0.0053
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0063 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0017 0.0029 0.0029
Schistosoma mansoni coup transcription factor 0.0021 0.0053 0.0053
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.1354 0.7176 0.7176
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.0063 0.0246
Trypanosoma brucei cyclin 9 0.0052 0.0218 0.1217
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0067 0.0363
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0227 0.1156 0.1156
Brugia malayi N-terminal motif family protein 0.019 0.0954 0.0954
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0124 0.0124
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0227 0.1156 0.1156
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0053 0.0053
Entamoeba histolytica hypothetical protein, conserved 0.0227 0.1156 0.463
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0124 0.0686
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0045 0.0045
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0117 0.0987
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0024 0.0024
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0065 0.029 0.1177
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0331 0.1859
Brugia malayi MBOAT family protein 0.0227 0.1156 0.1156
Brugia malayi TAR-binding protein 0.0111 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0128 0.0627 0.0627
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0476 0.2486 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0476 0.2486 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.001 0.0043
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0012 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0052 0.0218 0.0218
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0476 0.2486 1
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0215 0.1091 0.1091
Echinococcus multilocularis histone acetyltransferase MYST2 0.0049 0.0203 0.0203
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0063 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0218 0.0867
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0181 0.0248
Trichomonas vaginalis cyclin B, putative 0.0215 0.1091 0.4383
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0149 0.059
Giardia lamblia Cyclin A 0.0215 0.1091 0.4383
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Loa Loa (eye worm) hypothetical protein 0.019 0.0954 0.0954
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0053 0.0053
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0331 0.1859
Brugia malayi latrophilin 2 splice variant baaae 0.0128 0.0627 0.0627
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0476 0.2486 1
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0053 0.0053
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0045 0.0238
Trypanosoma cruzi glycerol uptake protein, putative 0.0227 0.1156 0.6524
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0034 0.0124 0.0124
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.0063 0.0246
Entamoeba histolytica hypothetical protein 0.0099 0.0472 0.1865
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0053 0.0053
Trypanosoma cruzi ISWI complex protein 0.0015 0.002 0.0099
Trichomonas vaginalis cyclin B3, putative 0.0052 0.0218 0.0867
Entamoeba histolytica cyclin C, putative 0.0052 0.0218 0.0838
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0021 0.0052 0.0052
Brugia malayi steroid hormone receptor 0.0021 0.0053 0.0053
Toxoplasma gondii exonuclease III APE 0.002 0.0045 0.0059
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0574 0.0574
Loa Loa (eye worm) hypothetical protein 0.0073 0.0331 0.0331
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0043 0.0171 0.146
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0728 0.0728
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0331 0.2783
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0063 0.0276 0.0276
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0215 0.1091 0.1091
Trichomonas vaginalis cyclin B, putative 0.0052 0.0218 0.0867
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0053 0.0053
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.0063 0.0507
Trypanosoma brucei mitotic cyclin 0.0052 0.0218 0.1217
Entamoeba histolytica cyclin family protein 0.0215 0.1091 0.4365
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.001 0.0031
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.0227 0.1269
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0023 0.0063 0.0339
Loa Loa (eye worm) hhat protein 0.0227 0.1156 0.1156
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Brugia malayi RNA binding protein 0.0111 0.0533 0.0533
Trypanosoma cruzi mitotic cyclin, putative 0.0052 0.0218 0.1217
Brugia malayi beta-lactamase 0.0073 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0053 0.0053
Leishmania major glycerol uptake protein, putative 0.0227 0.1156 0.6524
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0063 0.0063
Leishmania major glycerol uptake protein, putative 0.0227 0.1156 0.6524
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.1145 0.1145
Trichomonas vaginalis cyclin B3, putative 0.0215 0.1091 0.4383
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0063 0.0507
Echinococcus granulosus bloom syndrome protein 0.0025 0.0072 0.0072
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0476 0.2486 1
Loa Loa (eye worm) RecQ helicase 0.0025 0.0072 0.0072
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0128 0.0128
Brugia malayi mbt repeat family protein 0.0043 0.0171 0.0171
Trypanosoma cruzi glycerol uptake protein, putative 0.0227 0.1156 0.6524
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0053 0.0053
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0053 0.0053
Mycobacterium ulcerans aldehyde dehydrogenase 0.0101 0.048 0.4042
Trichomonas vaginalis cyclin B, putative 0.0215 0.1091 0.4383
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0012 0.0003 0.0003
Onchocerca volvulus 0.0021 0.0053 0.0438
Loa Loa (eye worm) glutathione reductase 0.0029 0.0093 0.0093
Loa Loa (eye worm) acetyltransferase 0.0147 0.0728 0.0728
Mycobacterium tuberculosis Conserved protein 0.0073 0.0331 0.1349
Trypanosoma brucei glycerol uptake protein, putative 0.0227 0.1156 0.6524
Schistosoma mansoni hypothetical protein 0.0227 0.1156 0.1156
Trypanosoma cruzi DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Echinococcus granulosus microtubule associated protein 2 0.0625 0.3281 0.3281
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0063 0.0506
Trypanosoma brucei DNA polymerase eta, putative 0.0054 0.0227 0.1269
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0.0002 0.0002
Trichomonas vaginalis cyclin D, putative 0.0215 0.1091 0.4383
Toxoplasma gondii hypothetical protein 0.0163 0.0813 0.113
Brugia malayi glutathione reductase 0.0029 0.0093 0.0093
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0331 0.2783
Brugia malayi Bromodomain containing protein 0.0077 0.0352 0.0352
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0063 0.0063
Brugia malayi MBOAT family protein 0.0227 0.1156 0.1156
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0024 0.0024
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0063 0.0063
Trypanosoma cruzi cyclin 9, putative 0.0052 0.0218 0.1217
Brugia malayi beta-lactamase family protein 0.0073 0.0331 0.0331
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0233 0.1184 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0162 0.0807 0.4546
Brugia malayi Hhat protein 0.0227 0.1156 0.1156
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0045 0.0169
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0331 0.1349
Echinococcus multilocularis cyclin b3 0.0215 0.1091 0.1091
Echinococcus granulosus cyclin b3 0.0215 0.1091 0.1091
Trichomonas vaginalis conserved hypothetical protein 0.0215 0.1091 0.4383
Brugia malayi Latrophilin receptor protein 2 0.0059 0.0258 0.0258
Trypanosoma cruzi GUP1, putative 0.0227 0.1156 0.6524
Giardia lamblia G2/mitotic-specific cyclin B 0.0215 0.1091 0.4383
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0093 0.0512
Schistosoma mansoni ap endonuclease 0.002 0.0045 0.0045
Mycobacterium ulcerans hypothetical protein 0.0073 0.0331 0.2783
Mycobacterium ulcerans DNA polymerase IV 0.0034 0.0124 0.1027
Loa Loa (eye worm) hypothetical protein 0.0227 0.1156 0.1156
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0476 0.2486 1
Echinococcus granulosus patatin phospholipase domain containing protein 0.0012 0.0003 0.0003
Brugia malayi Cyclin, N-terminal domain containing protein 0.0215 0.1091 0.1091
Trypanosoma cruzi DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0198 0.1102
Schistosoma mansoni zinc finger protein 0.0015 0.002 0.002
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0048 0.0048
Loa Loa (eye worm) cyclin C 0.0052 0.0218 0.0218
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0016 0.0024 0.0024
Plasmodium vivax cyclin homologue, putative 0.0052 0.0218 0.03
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.0063 0.0246
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0053 0.0053
Leishmania major DNA polymerase eta, putative 0.0054 0.0227 0.1269
Loa Loa (eye worm) hypothetical protein 0.0021 0.0052 0.0052
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0014 0.0014 0.0014
Schistosoma mansoni cyclin d 0.1882 1 1
Leishmania major hypothetical protein, conserved 0.0015 0.002 0.0099
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.0063 0.0507
Loa Loa (eye worm) hypothetical protein 0.0073 0.0331 0.0331
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0227 0.1156 0.1156
Loa Loa (eye worm) cytochrome P450 0.0023 0.0063 0.0063
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0048 0.0198 0.1102
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0045 0.0169
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0058 0.0058
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0045 0.0045
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0198 0.1102
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0053 0.0053
Echinococcus granulosus cyclins 0.0052 0.0218 0.0218
Brugia malayi Cyclin, N-terminal domain containing protein 0.0215 0.1091 0.1091
Mycobacterium tuberculosis Conserved protein 0.0073 0.0331 0.1349
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0029 0.0029
Leishmania major glycerol uptake protein, putative 0.0227 0.1156 0.6524
Echinococcus granulosus cyclin k 0.0052 0.0218 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0053 0.0053
Echinococcus multilocularis SAM and MBT domain containing protein 0.0043 0.0171 0.0171
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.0063 0.0507
Loa Loa (eye worm) CYL-1 protein 0.0052 0.0218 0.0218
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0059 0.0258 0.0258
Schistosoma mansoni cyclin B 0.0215 0.1091 0.1091
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.1354 0.7176 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0063 0.0507
Trypanosoma brucei glycerol uptake protein, putative 0.0227 0.1156 0.6524
Echinococcus granulosus o acyltransferase membrane bound domain 0.0227 0.1156 0.1156
Toxoplasma gondii thioredoxin reductase 0.0029 0.0093 0.0126
Plasmodium falciparum cyclin 1 0.0052 0.0218 0.03
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0053
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0045 0.0238
Schistosoma mansoni sex comb on midleg homolog 0.0043 0.0171 0.0171
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.0063 0.0507
Echinococcus granulosus chromobox protein 1 0.0059 0.0255 0.0255
Loa Loa (eye worm) TAR-binding protein 0.0111 0.0533 0.0533
Echinococcus granulosus dna polymerase eta 0.0054 0.0227 0.0227
Brugia malayi Cytochrome P450 family protein 0.0023 0.0063 0.0063
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0728 0.0728
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0533 0.0533
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0063 0.0506
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0045 0.0169
Mycobacterium tuberculosis Conserved protein 0.0073 0.0331 0.1349
Trichomonas vaginalis cyclin D, putative 0.0052 0.0218 0.0867
Loa Loa (eye worm) cyclin domain-containing protein 0.0052 0.0218 0.0218
Loa Loa (eye worm) latrophilin receptor protein 2 0.0059 0.0258 0.0258
Echinococcus multilocularis cyclin t1 0.0052 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0033 0.0117 0.0117
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0215 0.1091 0.6153
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0331 0.1349
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0024 0.0024
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.1354 0.7176 0.7176
Schistosoma mansoni hypothetical protein 0.0052 0.0218 0.0218
Trichomonas vaginalis chromobox protein, putative 0.0035 0.013 0.0512
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0052 0.0218 0.0218
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0053 0.0053
Schistosoma mansoni cytochrome P450 0.0023 0.0063 0.0063
Brugia malayi ecdysteroid receptor 0.0021 0.0053 0.0053
Schistosoma mansoni bromodomain containing protein 0.0065 0.029 0.029
Trichomonas vaginalis chromobox protein, putative 0.0035 0.013 0.0512
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.1354 0.7176 0.7176
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0012 0.0003 0.0003
Echinococcus granulosus histone acetyltransferase MYST2 0.0049 0.0203 0.0203
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0029 0.0029
Schistosoma mansoni g1/s-specific cyclin C 0.0052 0.0218 0.0218
Schistosoma mansoni cyclin G2 0.0052 0.0218 0.0218
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0331 0.0331
Trichomonas vaginalis cyclin B, putative 0.0052 0.0218 0.0867
Brugia malayi Cyclin, N-terminal domain containing protein 0.0052 0.0218 0.0218
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Mycobacterium tuberculosis Probable reductase 0.0065 0.029 0.1177
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0045 0.0172
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0053 0.0053
Echinococcus multilocularis tar DNA binding protein 0.0111 0.0533 0.0533
Toxoplasma gondii hypothetical protein 0.0055 0.0236 0.0324
Echinococcus granulosus cyclin 0.0052 0.0218 0.0218
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0331 0.0331
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0331 0.1349
Plasmodium falciparum thioredoxin reductase 0.0029 0.0093 0.0126
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0012 0.0003 0.0003
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0053 0.0438
Mycobacterium tuberculosis Conserved hypothetical protein 0.018 0.0905 0.3701
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0012 0.0003 0.0003
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0063 1
Leishmania major cyclin 9, putative 0.0052 0.0218 0.1217
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0476 0.2486 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.0063 0.0246
Trypanosoma cruzi DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Loa Loa (eye worm) MBOAT family protein 0.0227 0.1156 0.1156
Echinococcus granulosus cyclins 0.0215 0.1091 0.1091
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0053 0.0053
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0049 0.0203 0.0203
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0053 0.0053
Echinococcus multilocularis thioredoxin glutathione reductase 0.0029 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0059 0.0258 0.0258
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0016 0.0024 0.0024
Loa Loa (eye worm) MBOAT family protein 0.0227 0.1156 0.1156
Treponema pallidum fructose-bisphosphate aldolase 0.0476 0.2486 1
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0117 0.0459
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0053 0.0053
Echinococcus granulosus SAM and MBT domain containing protein 0.0043 0.0171 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0218 0.0867
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0375 0.0375
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0063 0.0276 0.0276
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0045 0.0059
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0029 0.0029
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0198 0.1102
Leishmania major DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.0063 0.0507
Brugia malayi MBOAT family protein 0.0227 0.1156 0.1156
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0227 0.1156 0.1156
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0059 0.0255 0.1016
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0227 0.1156 0.1156
Echinococcus multilocularis dna polymerase kappa 0.0034 0.0124 0.0124
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0045 0.0356
Entamoeba histolytica hypothetical protein 0.0099 0.0472 0.1865
Echinococcus multilocularis cyclin k 0.0052 0.0218 0.0218
Echinococcus multilocularis polycomb protein SCMH1 0.0043 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0227 0.1156 0.1156
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.0063 0.0507
Echinococcus multilocularis cyclin G2 0.0052 0.0218 0.0218
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0272 0.0272
Schistosoma mansoni terminal deoxycytidyl transferase 0.0034 0.0124 0.0124
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0053 0.0438
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0012 0.0003 0.0003
Plasmodium falciparum cyclin 0.0215 0.1091 0.1517
Echinococcus granulosus cyclins 0.0215 0.1091 0.1091
Loa Loa (eye worm) RNA binding protein 0.0111 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0073 0.0331 0.0331
Brugia malayi hypothetical protein 0.0099 0.0472 0.0472
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0181 0.0248
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0073 0.0329 0.1337
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0053 0.0053
Mycobacterium ulcerans lipase LipD 0.0073 0.0331 0.2783
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0029 0.0029
Echinococcus multilocularis cyclin 0.0052 0.0218 0.0218
Echinococcus multilocularis cyclins 0.0215 0.1091 0.1091
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0003 0.0003
Brugia malayi beta-lactamase family protein 0.0073 0.0331 0.0331
Entamoeba histolytica vacuolar protein sorting 26 0.0227 0.1156 0.463
Trypanosoma cruzi ISWI complex protein 0.0015 0.002 0.0099
Schistosoma mansoni hypothetical protein 0.0015 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0227 0.1156 0.4647
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0067 0.0363
Leishmania major hypothetical protein, conserved 0.0227 0.1156 0.6524
Echinococcus granulosus cyclin y 0.0052 0.0218 0.0218
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.0063 0.0246
Echinococcus multilocularis G1:S specific cyclin D1 0.1882 1 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.1126 0.596 0.596
Onchocerca volvulus 0.0081 0.0375 0.3228
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0574 0.0574
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0065 0.029 0.1177
Schistosoma mansoni chromobox protein 0.0059 0.0255 0.0255
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0024 0.0024
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0227 0.1156 0.1156
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0227 0.1156 0.463
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0053 0.0053
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0331 0.1324
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0053
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0052 0.0218 0.0218
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0052 0.0218 0.1217
Echinococcus multilocularis cyclins 0.0215 0.1091 0.1091
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0052 0.0218 0.0218
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0059 0.0258 0.0258
Echinococcus granulosus o acyltransferase membrane bound domain 0.0227 0.1156 0.1156
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0016 0.0024 0.0024
Loa Loa (eye worm) cyclin domain-containing protein 0.0052 0.0218 0.0218
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0342 0.1771 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0045 0.0238
Schistosoma mansoni aldehyde dehydrogenase 0.0101 0.048 0.048
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.1145 0.1145
Echinococcus multilocularis cyclins 0.0215 0.1091 0.1091
Leishmania major mitochondrial DNA polymerase beta 0.0342 0.1771 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0101 0.048 0.4042
Trypanosoma brucei trypanothione reductase 0.0029 0.0093 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0117 0.0459
Trichomonas vaginalis DNA polymerase eta, putative 0.0034 0.0124 0.0488
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0053 0.0053
Echinococcus granulosus cyclins 0.0215 0.1091 0.1091
Brugia malayi Heterochromatin protein 1 0.0059 0.0255 0.0255
Leishmania major cyclin 0.0215 0.1091 0.6153
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.0063 0.0507
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0053 0.0053
Echinococcus multilocularis sterol O acyltransferase 1 0.0227 0.1156 0.1156
Entamoeba histolytica cyclin, putative 0.0215 0.1091 0.4365
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0053 0.0053
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0012 0.0003 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0124 0.0686
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.0063 0.0507
Trichomonas vaginalis cyclin D, putative 0.0215 0.1091 0.4383
Trichomonas vaginalis cyclins, putative 0.0052 0.0218 0.0867
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0021 0.0052 0.0052
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0101 0.048 0.2699
Toxoplasma gondii cytochrome p450 superfamily protein 0.0879 0.464 0.6464
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0035 0.013 0.1103
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Loa Loa (eye worm) hypothetical protein 0.0215 0.1091 0.1091
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0052 0.0218 0.0218
Brugia malayi mbt repeat family protein 0.0043 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0124 0.0602 0.0602
Loa Loa (eye worm) cyclin domain-containing protein 0.0052 0.0218 0.0218
Trichomonas vaginalis cyclins, putative 0.0215 0.1091 0.4383
Echinococcus granulosus geminin 0.0518 0.2708 0.2708
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0029 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0476 0.2486 1
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0227 0.1156 0.1156
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0342 0.1771 1
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0052 0.0052
Trypanosoma cruzi GUP1, putative 0.0227 0.1156 0.6524
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0058 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0225 0.1145 0.1145
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.0063 0.0507
Echinococcus granulosus o acyltransferase membrane bound domain 0.0227 0.1156 0.1156
Loa Loa (eye worm) hypothetical protein 0.0227 0.1156 0.1156
Loa Loa (eye worm) hypothetical protein 0.0073 0.0331 0.0331
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0128 0.0128
Schistosoma mansoni aldehyde dehydrogenase 0.0101 0.048 0.048
Mycobacterium leprae Probable lipase LipE 0.0073 0.0331 0.2783
Schistosoma mansoni myelin transcription factor 1 myt1 0.0049 0.0203 0.0203
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0024 0.0024
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0331 0.1349
Loa Loa (eye worm) cyclin domain-containing protein 0.0052 0.0218 0.0218
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0331 0.1324
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0053 0.0053
Trypanosoma cruzi glycerol uptake protein, putative 0.0227 0.1156 0.6524
Mycobacterium ulcerans beta-lactamase 0.0073 0.0331 0.2783
Giardia lamblia Cyclin fold protein 1, putative 0.0052 0.0218 0.0867
Schistosoma mansoni chromobox protein 0.0059 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0053
Echinococcus granulosus voltage gated potassium channel 0.0021 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0026 0.0079 0.0079
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0045 0.0059
Loa Loa (eye worm) hypothetical protein 0.0045 0.0182 0.0182
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.0063 0.0507
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0024 0.0024
Trichomonas vaginalis cyclin A, putative 0.0215 0.1091 0.4383
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0053 0.0053
Echinococcus multilocularis zinc finger protein 0.0023 0.0062 0.0062
Brugia malayi Cyclin, N-terminal domain containing protein 0.0052 0.0218 0.0218
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.0063 0.0246
Toxoplasma gondii hypothetical protein 0.0227 0.1156 0.1608
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.0024
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0101 0.048 0.1959
Echinococcus granulosus cGMP dependent protein kinase 1 0.0012 0.0003 0.0003
Trichomonas vaginalis cyclin A, putative 0.0052 0.0218 0.0867
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0065 0.0251
Brugia malayi hypothetical protein 0.0052 0.0218 0.0218
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0003 0.0003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0059 0.0254 0.1421
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0101 0.048 0.048
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.0063 0.0507
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0331 0.1349
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0073 0.0329 0.2759
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0181 0.0181
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0331 0.1324
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.0063 0.0507
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.0063 0.0246
Schistosoma mansoni zinc finger protein 0.0227 0.1156 0.1156
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0476 0.2486 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0053 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0053 0.0053
Giardia lamblia Hypothetical protein 0.0052 0.0218 0.0867
Leishmania major mitotic cyclin, putative 0.0052 0.0218 0.1217
Schistosoma mansoni hypothetical protein 0.0012 0.0003 0.0003
Brugia malayi hypothetical protein 0.0052 0.0218 0.0218
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0233 0.1184 1
Loa Loa (eye worm) hypothetical protein 0.0188 0.0944 0.0944
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0306 0.0306
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0533 0.0533
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0053 0.0053
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0029 0.0029
Loa Loa (eye worm) hhat protein 0.0227 0.1156 0.1156
Trichomonas vaginalis transmembrane protein nessy, putative 0.0227 0.1156 0.4647
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0227 0.1156 0.1156
Echinococcus multilocularis chromobox protein 1 0.0059 0.0255 0.0255
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0072 0.0072
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0052 0.0218 0.0218
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0012 0.0002 0.0002
Loa Loa (eye worm) cyclin domain-containing protein 0.0052 0.0218 0.0218
Mycobacterium ulcerans aldehyde dehydrogenase 0.0101 0.048 0.4042
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0053
Plasmodium vivax thioredoxin reductase, putative 0.0029 0.0093 0.0126
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0124 0.0686
Schistosoma mansoni hypothetical protein 0.0059 0.0258 0.0258
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0052 0.0052
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0053 0.0053
Echinococcus multilocularis cyclins 0.0215 0.1091 0.1091
Echinococcus granulosus cyclin A3 4 0.0052 0.0218 0.0218
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0174 0.0871 0.0871
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.0063 0.0246
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.0227 0.0227
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0012 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.0063 0.0246
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0024 0.0024
Giardia lamblia Cyclin B-like protein 0.0052 0.0218 0.0867
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0227 0.1156 0.463
Leishmania major cytochrome p450-like protein 0.0023 0.0063 0.0339
Trypanosoma brucei unspecified product 0.0034 0.0124 0.0686
Loa Loa (eye worm) hypothetical protein 0.0043 0.0171 0.0171
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0003 0.0003
Echinococcus granulosus cyclin y 0.0052 0.0218 0.0218
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0162 0.0807 0.4546
Trypanosoma cruzi DNA polymerase eta, putative 0.003 0.01 0.0552
Echinococcus granulosus cyclin G2 0.0052 0.0218 0.0218
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0029 0.0093 0.0372
Loa Loa (eye worm) hypothetical protein 0.0043 0.0172 0.0172
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0331 0.1349
Mycobacterium ulcerans hypothetical protein 0.018 0.0905 0.7637
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0124 0.0498
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0255 0.1015
Giardia lamblia Fructose-bisphosphate aldolase 0.0476 0.2486 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0045 0.0238
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0034 0.0124 0.0498
Echinococcus granulosus cyclin G2 0.0052 0.0218 0.0218
Plasmodium falciparum diacylglycerol O-acyltransferase 0.1354 0.7176 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0058 0.0058
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0053 0.0053
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0099 0.0472 0.0472
Schistosoma mansoni hypothetical protein 0.0023 0.0063 0.0063
Leishmania major glycerol uptake protein, putative 0.0227 0.1156 0.6524
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0053 0.0053
Brugia malayi Cyclin, N-terminal domain containing protein 0.0052 0.0218 0.0218
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0227 0.1156 0.1156
Echinococcus granulosus dna polymerase kappa 0.0034 0.0124 0.0124
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.092 0.4856 0.4856
Loa Loa (eye worm) hypothetical protein 0.0052 0.0218 0.0218
Trypanosoma cruzi mitotic cyclin, putative 0.0052 0.0218 0.1217
Schistosoma mansoni sex comb on midleg homolog 0.0043 0.0171 0.0171
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.0063 0.0246
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0012 0.0003 0.0003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0053 0.0053
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0467 0.2439 1
Brugia malayi Cytochrome P450 family protein 0.0023 0.0063 0.0063
Brugia malayi MH2 domain containing protein 0.0118 0.0574 0.0574
Echinococcus granulosus G1:S specific cyclin D1 0.1882 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0305 0.0305
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0053 0.0053
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0099 0.0472 0.0472
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Toxoplasma gondii hypothetical protein 0.0052 0.0218 0.03
Onchocerca volvulus Cyclin L homolog 0.0052 0.0218 0.1865
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.0063 0.0246
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0069 0.031 0.031
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0225 0.1145 0.1145
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0063 0.0083
Toxoplasma gondii ABC1 family protein 0.0073 0.0331 0.0458
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0218 0.0867
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0012 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0099 0.0472 0.1865
Onchocerca volvulus 0.0073 0.0331 0.2849
Schistosoma mansoni zinc finger protein 0.0023 0.0062 0.0062
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0045 0.0139
Schistosoma mansoni hypothetical protein 0.002 0.0048 0.0048
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.0063 0.0246
Trichomonas vaginalis cyclins, putative 0.0215 0.1091 0.4383
Plasmodium falciparum glutathione reductase 0.0029 0.0093 0.0126
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0225 0.1145 0.1145
Brugia malayi PHD-finger family protein 0.0028 0.009 0.009
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0023 0.0063 0.0507
Trypanosoma cruzi cyclin, putative 0.0215 0.1091 0.6153
Echinococcus multilocularis geminin 0.0518 0.2708 0.2708
Echinococcus multilocularis cyclins 0.0215 0.1091 0.1091
Loa Loa (eye worm) AGC/PKG protein kinase 0.0012 0.0003 0.0003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0059 0.0255 0.1016
Leishmania major hypothetical protein, conserved 0.0073 0.0331 0.1859
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0305 0.0305
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0012 0.0003 0.0003
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0034 0.0124 0.0488
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0218 0.03
Echinococcus granulosus tar DNA binding protein 0.0111 0.0533 0.0533
Brugia malayi Egg laying defective protein 4 0.0012 0.0003 0.0003
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0012 0.0003 0.0003
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0024 0.0024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0225 0.1145 0.1145
Loa Loa (eye worm) beta-lactamase 0.0073 0.0331 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0218 0.0867
Trypanosoma cruzi DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Schistosoma mansoni hypothetical protein 0.0518 0.2708 0.2708
Entamoeba histolytica cyclin, putative 0.0215 0.1091 0.4365
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.0003 0.0003
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0056 0.0074
Brugia malayi cytochrome P450 0.0023 0.0063 0.0063
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0052 0.0218 0.03
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0045 0.0169
Loa Loa (eye worm) hypothetical protein 0.0051 0.0213 0.0213
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0043 0.0171 0.0171
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0063 0.0241
Echinococcus granulosus cyclins 0.0215 0.1091 0.1091
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0016 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0331 0.1859
Loa Loa (eye worm) MBOAT family protein 0.0227 0.1156 0.1156
Entamoeba histolytica deoxycytidyl transferase, putative 0.0034 0.0124 0.0459
Loa Loa (eye worm) hypothetical protein 0.183 0.9722 0.9722
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0052 0.0218 0.03
Echinococcus multilocularis cyclins 0.0215 0.1091 0.1091
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0124 0.0686
Schistosoma mansoni hypothetical protein 0.0059 0.0258 0.0258
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0181 0.0717
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0053 0.0053
Echinococcus granulosus zinc finger protein 0.0023 0.0062 0.0062
Leishmania major mitotic cyclin, putative 0.0052 0.0218 0.1217
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0063 0.0339
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0331 0.0331
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.01 0.0136
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0533 0.0533
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0375 0.0375
Entamoeba histolytica cyclin family protein 0.0215 0.1091 0.4365
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0728 0.0728
Mycobacterium leprae putative cytochrome p450 0.0023 0.0063 0.0507
Trichomonas vaginalis cyclins, putative 0.0215 0.1091 0.4383
Echinococcus multilocularis cyclin A3 4 0.0052 0.0218 0.0218
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0012 0.0003 0.0003
Echinococcus granulosus polycomb protein SCMH1 0.0043 0.0171 0.0171
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0052 0.0218 0.03
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0331 0.1349
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.0063 0.0507
Trichomonas vaginalis cyclins, putative 0.0052 0.0218 0.0867
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0053 0.0053
Loa Loa (eye worm) diacylglycerol acyltransferase 0.1354 0.7176 0.7176
Schistosoma mansoni cyclin G 0.0052 0.0218 0.0218
Giardia lamblia Hypothetical protein 0.0215 0.1091 0.4383

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) Inhibition of clasto-lactacystin binding to beta5 subunit of 20S proteasome in human HeLa cells at 1 uM by Western blotting analysis ChEMBL. 18801655
Activity (binding) Inhibition of clasto-lactacystin binding to beta2 subunit of 20S proteasome in human HeLa cells at 1 uM by Western blotting analysis ChEMBL. 18801655

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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