Detailed information for compound 1127571

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 632.631 | Formula: C30H35F3N6O6
  • H donors: 4 H acceptors: 5 LogP: 3.31 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC[C@H](N1C[C@H](C)[C@@H](CN(C(=O)Nc2ccc(cc2)C(F)(F)F)C)Oc2c(C1=O)cc(cc2)NC(=O)Nc1c(C)noc1C)C
  • InChi: 1S/C30H35F3N6O6/c1-16-13-39(17(2)15-40)27(41)23-12-22(34-28(42)36-26-18(3)37-45-19(26)4)10-11-24(23)44-25(16)14-38(5)29(43)35-21-8-6-20(7-9-21)30(31,32)33/h6-12,16-17,25,40H,13-15H2,1-5H3,(H,35,43)(H2,34,36,42)/t16-,17+,25+/m0/s1
  • InChiKey: LXSDQSBECRGXGK-RJYGXOMWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cathepsin L-like precursor 0.003 0.0053 0.0075
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.001 0.0003 0.0002
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0012 0.0009 0.0373
Entamoeba histolytica hypothetical protein 0.0037 0.0071 0.037
Echinococcus multilocularis SWI:SNF matrix associated 0.0029 0.0052 0.0169
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0071
Brugia malayi Protein kinase domain containing protein 0.0072 0.0159 0.023
Entamoeba histolytica hypothetical protein 0.0016 0.002 0.0088
Toxoplasma gondii beta tubulin 0.0123 0.0287 0.0284
Onchocerca volvulus 0.1312 0.3277 1
Schistosoma mansoni opsin-like receptor 0.0253 0.0615 0.3395
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0053 0.0175
Schistosoma mansoni multidrug resistance protein 0.0011 0.0007 0.0023
Echinococcus multilocularis cathepsin L cysteine protease 0.0044 0.009 0.0296
Schistosoma mansoni elongin B 0.0197 0.0474 0.2614
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0122 0.0285 0.0932
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Echinococcus granulosus serine protease inhibitor 0.0012 0.0008 0.0028
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0005 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0253 0.0615 0.3395
Trypanosoma brucei unspecified product 0.0039 0.0078 0.0424
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0036 0.0178
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0071 0.038
Loa Loa (eye worm) hypothetical protein 0.2593 0.6496 0.9518
Leishmania major hypothetical protein, conserved 0.003 0.0055 0.0298
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0005 0.0025
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Schistosoma mansoni tubulin subunit beta 0.0123 0.0287 0.1577
Brugia malayi hypothetical protein 0.0099 0.0226 0.0328
Schistosoma mansoni glutamate receptor kainate 0.0034 0.0065 0.0345
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0009 0.0037
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0055 0.029
Loa Loa (eye worm) hypothetical protein 0.0169 0.0403 0.059
Loa Loa (eye worm) STAT protein 0.0047 0.0096 0.0141
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0009 0.0052
Trichomonas vaginalis tubulin gamma chain, putative 0.0123 0.0287 0.1577
Echinococcus granulosus tubulin subunit beta 0.0123 0.0287 0.0939
Trypanosoma brucei oligopeptidase b 0.0009 0.0001 0.0002
Brugia malayi neuropeptide F receptor 0.0253 0.0615 0.0898
Entamoeba histolytica ABC transporter, putative 0.0011 0.0007 0.0013
Mycobacterium ulcerans leucyl aminopeptidase 0.0056 0.012 0.5478
Schistosoma mansoni serine protease inhibitors serpins 0.0012 0.0008 0.0034
Leishmania major ABC-thiol transporter 0.0011 0.0007 0.0029
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0011 0.0007 0.0029
Echinococcus granulosus elongin b 0.0197 0.0474 0.1551
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.001 0.0005 0.0003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1225 0.3057 1
Echinococcus multilocularis serine protease inhibitor 0.0012 0.0008 0.0028
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0089 0.0202 0.1104
Schistosoma mansoni serine protease inhibitors serpins 0.0012 0.0008 0.0034
Loa Loa (eye worm) hypothetical protein 0.0241 0.0585 0.0857
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0122 0.0285 0.0932
Brugia malayi hypothetical protein 0.0253 0.0615 0.0898
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0253 0.0615 0.3395
Mycobacterium ulcerans hypothetical protein 0.0012 0.0009 0.0373
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0011 0.0006 0.0019
Brugia malayi RNase H family protein 0.0011 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Loa Loa (eye worm) serpin 0.0012 0.0008 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0133 0.0194
Trypanosoma cruzi cytochrome P450, putative 0.001 0.0005 0.0027
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0044 0.009 0.0132
Brugia malayi PHD-finger family protein 0.003 0.0053 0.0075
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0078 0.043
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0055 0.029
Brugia malayi polk-prov protein 0.0012 0.0009 0.001
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0173 0.0947
Giardia lamblia Beta tubulin 0.0123 0.0287 0.1559
Brugia malayi Cathepsin L-like cysteine proteinase 0.003 0.0053 0.0075
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0012
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0071 0.01
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0015 0.0016 0.0019
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.006 0.0129 0.038
Brugia malayi Serotonin receptor 0.0253 0.0615 0.0898
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0012 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0005 0.0025
Echinococcus granulosus sex peptide receptor 0.0253 0.0615 0.2012
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.005 0.0105 0.0583
Echinococcus multilocularis integrin alpha ps 0.0144 0.0341 0.1114
Plasmodium vivax tubulin beta chain, putative 0.0123 0.0287 0.1576
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0056 0.012 0.0648
Onchocerca volvulus 0.0253 0.0615 0.1866
Brugia malayi Papain family cysteine protease containing protein 0.0023 0.0036 0.0049
Echinococcus granulosus tachykinin peptides receptor 99D 0.0535 0.1322 0.4326
Echinococcus granulosus integrin beta 2 0.0172 0.0412 0.1347
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0023 0.0036 0.0116
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0253 0.0615 0.0898
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0029 0.0052 0.0169
Brugia malayi cathepsin F-like cysteine proteinase 0.0015 0.0016 0.0019
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0136 0.075
Chlamydia trachomatis 3-hydroxyacyl-ACP dehydratase 0.0131 0.0307 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0026 0.0044 0.0246
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0029 0.0052 0.0271
Entamoeba histolytica ATP-binding cassette protein, putative 0.0011 0.0007 0.0013
Brugia malayi serpin 0.0012 0.0008 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0031 0.0046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.009 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0044 0.009 0.0295
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0009 0.0373
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Echinococcus granulosus transcription elongation factor b polypeptide 1 0.0043 0.0086 0.0281
Loa Loa (eye worm) glutamate receptor 0.001 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0095 0.0217 0.0318
Echinococcus multilocularis enteropeptidase 0.0095 0.0217 0.0711
Trypanosoma brucei ribonuclease H1 0.0011 0.0007 0.0035
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0093 0.0213 0.1175
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0078 0.3533
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0085 0.0279
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0011 0.0007 0.0254
Echinococcus granulosus enteropeptidase 0.0095 0.0217 0.0711
Trypanosoma cruzi WLM domain containing protein, putative 0.001 0.0005 0.0025
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0078 0.0175 0.0254
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0253 0.0615 0.3395
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.001 0.0003 0.0005
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.002 0.0028 0.0093
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0015 0.0016 0.0022
Schistosoma mansoni phd/f-box containing protein 0.001 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0111 0.0257 0.0254
Brugia malayi Kelch motif family protein 0.0035 0.0067 0.0095
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0036 0.0116
Schistosoma mansoni hypothetical protein 0.0025 0.0041 0.0213
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0078
Leishmania major geranylgeranyltransferase, putative 0.0037 0.0071 0.0387
Trypanosoma brucei unspecified product 0.0027 0.0047 0.0254
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0052
Echinococcus multilocularis tyrosine kinase 0.001 0.0004 0.0014
Schistosoma mansoni glutamate receptor NMDA 0.008 0.0179 0.0979
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0005 0.0015
Echinococcus multilocularis glutamate receptor 2 0.0044 0.009 0.0295
Echinococcus granulosus JmjC domain containing protein 4 0.001 0.0003 0.0009
Echinococcus multilocularis cathepsin L cysteine protease 0.0044 0.009 0.0296
Echinococcus multilocularis leucine aminopeptidase protein 0.0056 0.012 0.0391
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0071 0.038
Schistosoma mansoni hypothetical protein 0.0025 0.0041 0.0213
Onchocerca volvulus Deterin homolog 0.0096 0.022 0.0659
Leishmania major pentamidine resistance protein 1 0.0011 0.0007 0.0029
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0096 0.0314
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0025 0.0041 0.0134
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0109 0.0599
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Onchocerca volvulus 0.0012 0.0008 0.0013
Trypanosoma brucei unspecified product 0.0012 0.001 0.0049
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Brugia malayi AF-10 protein 0.001 0.0003 0.0001
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0011 0.0006 0.0009
Onchocerca volvulus 0.04 0.0984 0.2993
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0071 0.0394
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0331 0.1084
Onchocerca volvulus 0.0044 0.009 0.0264
Loa Loa (eye worm) beta-tubulin 0.0123 0.0287 0.042
Echinococcus multilocularis glutamate receptor 2 0.0025 0.004 0.0132
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus multilocularis g protein coupled receptor 0.0253 0.0615 0.2012
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0082 0.008
Echinococcus multilocularis cysteine protease 0.0044 0.009 0.0296
Trichomonas vaginalis ribonuclease H1, putative 0.0011 0.0007 0.0027
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0078 0.0419
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0051 0.0107 0.4871
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Entamoeba histolytica hypothetical protein 0.0037 0.0071 0.037
Brugia malayi ecdysteroid receptor 0.001 0.0005 0.0003
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0025 0.0041 0.0134
Schistosoma mansoni integrin alpha 0.0144 0.0341 0.1874
Schistosoma mansoni phosphoglucomutase 0.0011 0.0007 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0005 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Echinococcus granulosus leucine aminopeptidase protein 0.0056 0.012 0.0391
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0078 0.0113
Echinococcus granulosus FTZ F1 alpha 0.001 0.0005 0.0015
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0009 0.0046
Echinococcus granulosus sodium:glucose cotransporter 0.0039 0.0077 0.0252
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0039 0.0077 0.0252
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.001 0.0003 0.0011
Echinococcus multilocularis glycoprotein Antigen 5 0.0095 0.0217 0.0711
Brugia malayi hypothetical protein 0.0197 0.0474 0.0691
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0012 0.0009 0.0373
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0122 0.0285 0.1557
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0009 0.0373
Brugia malayi serpin 0.0012 0.0008 0.0009
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0078 0.0423
Trypanosoma brucei protein phosphatase 2B, putative 0.0011 0.0006 0.0027
Onchocerca volvulus 0.0049 0.0102 0.03
Brugia malayi putative neuropeptide receptor 0.0253 0.0615 0.0898
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0005 0.0012
Schistosoma mansoni multidrug resistance protein 0.0011 0.0007 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0005 0.0003
Echinococcus granulosus neuropeptide receptor 0.0253 0.0615 0.2012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0011
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0039 0.0077 0.0252
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0013 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0009 0.0046
Brugia malayi hypothetical protein 0.0016 0.0019 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0253 0.0615 0.3395
Echinococcus multilocularis microtubule associated protein 2 0.0704 0.1749 0.5721
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0005 0.0015
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0011 0.0007 0.0254
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0005 0.0015
Brugia malayi jmjC domain containing protein 0.0037 0.0071 0.01
Schistosoma mansoni growth hormone secretagogue receptor 0.0253 0.0615 0.3395
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0005 0.0007
Loa Loa (eye worm) BEN-1 protein 0.0123 0.0287 0.042
Mycobacterium tuberculosis Conserved protein 0.0037 0.0071 0.0386
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0012 0.0009 0.0029
Onchocerca volvulus 0.005 0.0105 0.0309
Trypanosoma cruzi protein farnesyltransferase, putative 0.0111 0.0257 0.1423
Echinococcus granulosus cathepsin l1 0.003 0.0053 0.0175
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0105 0.0583
Brugia malayi Trypsin family protein 0.0095 0.0217 0.0315
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0011 0.0007 0.0036
Brugia malayi hypothetical protein 0.0012 0.0008 0.0009
Echinococcus granulosus g-protein coupled receptor 0.0253 0.0615 0.2012
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Schistosoma mansoni hypothetical protein 0.0014 0.0013 0.0058
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0109 0.0358
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0009 0.001
Echinococcus granulosus voltage dependent calcium channel 0.001 0.0003 0.0011
Toxoplasma gondii serpin (serine proteinase inhibitor) superfamily protein 0.0012 0.0008 0.0006
Schistosoma mansoni biogenic amine (5HT) receptor 0.0253 0.0615 0.3395
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0111 0.0257 0.1418
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0011 0.0007 0.0254
Brugia malayi Cathepsin L-like precursor 0.0015 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0096 0.022 0.0322
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0071 0.0232
Echinococcus multilocularis voltage dependent calcium channel 0.001 0.0003 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Brugia malayi Cytochrome P450 family protein 0.001 0.0005 0.0004
Plasmodium falciparum phd finger protein, putative 0.003 0.0053 0.0281
Onchocerca volvulus 0.001 0.0005 0.0001
Brugia malayi N-terminal motif family protein 0.006 0.0129 0.0185
Schistosoma mansoni hypothetical protein 0.0069 0.0152 0.0829
Loa Loa (eye worm) hypothetical protein 0.0095 0.0217 0.0318
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0036 0.0178
Trypanosoma brucei multidrug resistance protein E 0.0011 0.0007 0.0031
Echinococcus granulosus neuropeptide Y receptor 0.0253 0.0615 0.2012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0096 0.0518
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0009 0.0052
Echinococcus granulosus rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Plasmodium falciparum cysteine repeat modular protein 1 0.0072 0.0159 0.0867
Leishmania major serine/threonine protein phosphatase, putative 0.0011 0.0006 0.0025
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0015 0.0015 0.0072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0071 0.0104
Schistosoma mansoni hypothetical protein 0.0041 0.0083 0.0444
Schistosoma mansoni hypothetical protein 0.003 0.0053 0.0282
Schistosoma mansoni biogenic amine (5HT) receptor 0.0253 0.0615 0.3395
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0005 0.002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0253 0.0615 0.3395
Echinococcus multilocularis GPCR, family 2 0.0025 0.0041 0.0134
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0015 0.0015 0.005
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0071 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0015 0.0072
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0253 0.0615 0.2012
Schistosoma mansoni serine protease inhibitors serpins 0.0012 0.0008 0.0034
Brugia malayi G-protein coupled receptor 0.0253 0.0615 0.0898
Onchocerca volvulus Prolyl endopeptidase homolog 0.0023 0.0036 0.0096
Echinococcus granulosus tm gpcr rhodopsin 0.0253 0.0615 0.2012
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.001 0.0004 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0009 0.0046
Loa Loa (eye worm) hypothetical protein 0.0095 0.0217 0.0318
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Plasmodium falciparum tubulin beta chain 0.0123 0.0287 0.1576
Echinococcus granulosus solute carrier family 5 0.0039 0.0077 0.0252
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.04 0.0984 0.5439
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0071 0.038
Echinococcus multilocularis cysteine protease 0.0044 0.009 0.0296
Brugia malayi ABC transporter transmembrane region family protein 0.0011 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0009
Onchocerca volvulus 0.003 0.0053 0.0151
Onchocerca volvulus 0.001 0.0005 0.0001
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0074 0.0393
Schistosoma mansoni hypothetical protein 0.0049 0.0102 0.0554
Loa Loa (eye worm) latrophilin receptor protein 2 0.0025 0.0041 0.0059
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0013 0.0012 0.0014
Leishmania major oxidoreductase-like protein 0.0011 0.0007 0.003
Brugia malayi brahma associated protein 60 kDa 0.0029 0.0052 0.0072
Brugia malayi Guanylyl cyclase protein 23 0.001 0.0004 0.0003
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0013 0.0042
Brugia malayi PHD-finger family protein 0.001 0.0005 0.0003
Echinococcus granulosus caspase 8 0.0015 0.0015 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0253 0.0615 0.3395
Entamoeba histolytica cysteine protease, putative 0.0044 0.009 0.0478
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Entamoeba histolytica tubulin family protein 0.0123 0.0287 0.1569
Brugia malayi G-protein coupled receptor 0.0253 0.0615 0.0898
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Trypanosoma brucei protein kinase, putative 0.0052 0.0109 0.06
Echinococcus granulosus dro:myosuppressin receptor 0.0253 0.0615 0.2012
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0111 0.0257 0.1411
Plasmodium vivax geranylgeranyltransferase, putative 0.0037 0.0071 0.0379
Echinococcus granulosus rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.001 0.0005 0.0001
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Brugia malayi multidrug resistance related protein 1 0.0011 0.0007 0.0006
Echinococcus multilocularis SWI:SNF matrix associated 0.0029 0.0052 0.0169
Loa Loa (eye worm) melatonin receptor type 1A 0.0253 0.0615 0.0901
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0083 0.027
Onchocerca volvulus 0.0029 0.0052 0.0145
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0055 0.029
Toxoplasma gondii cathepsin CPL 0.0044 0.009 0.0088
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.005 0.0105 0.0562
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0003 0.0004
Brugia malayi beta-lactamase family protein 0.0037 0.0071 0.01
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.001 0.0003 0.0011
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0009 0.0038
Schistosoma mansoni hypothetical protein 0.0198 0.0477 0.263
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0012 0.0039
Trypanosoma cruzi cysteine proteinase, putative 0.0023 0.0036 0.02
Echinococcus granulosus eukaryotic initiation factor 4A 0.0727 0.1807 0.591
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0217 0.1191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.009 0.0488
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0023 0.0036 0.0187
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0096 0.014
Trypanosoma brucei lanosterol synthase 0.0093 0.0213 0.1177
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.009 0.0488
Brugia malayi beta-tubulin, identical 0.0123 0.0287 0.0417
Onchocerca volvulus 0.001 0.0005 0.0001
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0109 0.0358
Schistosoma mansoni hypothetical protein 0.0029 0.0052 0.0273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0321 0.1052
Loa Loa (eye worm) RGC/RGC protein kinase 0.001 0.0004 0.0006
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0037 0.0071 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0015 0.0072
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Toxoplasma gondii hypothetical protein 0.004 0.0079 0.0076
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus multilocularis Tubulin beta 2C chain 0.0123 0.0287 0.0939
Echinococcus multilocularis nmda type glutamate receptor 0.0071 0.0156 0.0512
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0012 0.0009 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0009 0.0046
Leishmania major DNA polymerase kappa, putative 0.0012 0.0009 0.0045
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0006
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0044 0.009 0.0295
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0078
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.001 0.0005 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Toxoplasma gondii beta-tubulin, putative 0.0123 0.0287 0.0284
Echinococcus granulosus g protein coupled receptor 0.0253 0.0615 0.2012
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0074 0.0165 0.0897
Trypanosoma brucei Metacaspase-4 0.0015 0.0015 0.008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0253 0.0615 0.3395
Schistosoma mansoni protein phosphatase-2b 0.0011 0.0006 0.0019
Schistosoma mansoni integrin alpha-ps 0.0175 0.0418 0.2303
Echinococcus granulosus caspase 2 0.0056 0.0119 0.039
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0009 0.0001 0.0002
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.001 0.0005 0.0025
Trypanosoma cruzi metacaspase, putative 0.0015 0.0015 0.0085
Giardia lamblia MRP-like ABC transporter 0.0011 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0109 0.0107
Brugia malayi Receptor family ligand binding region containing protein 0.001 0.0004 0.0003
Trypanosoma brucei metacaspase 0.0015 0.0015 0.008
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0111 0.0257 0.1411
Treponema pallidum sodium- and chloride- dependent transporter 0.0028 0.0049 0.023
Onchocerca volvulus Transcription elongation factor B polypeptide 1 homolog 0.0043 0.0086 0.0249
Plasmodium vivax RNA helicase-1, putative 0.0727 0.1807 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0011 0.0007 0.0004
Brugia malayi Glutamate receptor 1 precursor 0.0034 0.0065 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0253 0.0615 0.3395
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0089 0.0202 0.0292
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Brugia malayi Trypsin family protein 0.0095 0.0217 0.0315
Schistosoma mansoni tubulin subunit beta 0.0123 0.0287 0.1577
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0253 0.0615 0.2012
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0074 0.0386
Schistosoma mansoni hypothetical protein 0.0029 0.0052 0.0273
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0083 0.027
Onchocerca volvulus 0.0072 0.0159 0.0473
Trypanosoma cruzi WLM domain containing protein, putative 0.001 0.0005 0.0025
Echinococcus granulosus receptor type guanylyl cyclase 0.001 0.0004 0.0014
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0727 0.1807 1
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0727 0.1807 0.591
Schistosoma mansoni myosin xvIII 0.0253 0.0615 0.3395
Schistosoma mansoni amine GPCR 0.0253 0.0615 0.3395
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Brugia malayi RE15519p 0.0253 0.0615 0.0898
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0727 0.1807 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0123 0.0287 0.0939
Loa Loa (eye worm) ctsf protein 0.0044 0.009 0.0132
Loa Loa (eye worm) hypothetical protein 0.006 0.0129 0.0188
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0015 0.0015 0.0013
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0037 0.0071 0.0381
Brugia malayi hypothetical protein 0.003 0.0055 0.0077
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0037 0.0071 0.0379
Brugia malayi hypothetical protein 0.0241 0.0585 0.0854
Onchocerca volvulus 0.0015 0.0017 0.0039
Trypanosoma cruzi metacaspase, putative 0.0015 0.0015 0.0085
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Loa Loa (eye worm) hypothetical protein 0.0037 0.0071 0.0104
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0003 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0005 0.0015
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0032 0.0058 0.0315
Schistosoma mansoni multidrug resistance protein 0.0011 0.0007 0.0023
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0253 0.0615 0.3395
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0009 0.0002 0.0003
Brugia malayi BmSERPIN, truncated 0.0012 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0012 0.0009 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0015 0.0072
Echinococcus multilocularis beta tubulin 0.0123 0.0287 0.0939
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0015 0.0015 0.0072
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus multilocularis caspase 8 0.0015 0.0015 0.005
Echinococcus multilocularis cathepsin L 0.0023 0.0036 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Onchocerca volvulus Cathepsin L homolog 0.0044 0.009 0.0264
Leishmania major hypothetical protein, conserved 0.0037 0.0071 0.0386
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0044 0.009 0.0132
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.001 0.0005 0.0012
Brugia malayi Probable ATP-dependent helicase DHX35 0.0022 0.0033 0.0044
Echinococcus granulosus cysteine protease 0.0023 0.0036 0.0118
Schistosoma mansoni serpin 0.0012 0.0008 0.0034
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0078 0.0417
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Trypanosoma brucei beta tubulin 0.0123 0.0287 0.1584
Echinococcus multilocularis transmembrane protease serine 3 0.0095 0.0217 0.0711
Echinococcus granulosus voltage gated potassium channel 0.0013 0.0012 0.0039
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0071 0.5887
Plasmodium falciparum cysteine proteinase falcipain 3 0.0044 0.009 0.0486
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0122 0.0285 0.1565
Echinococcus granulosus neuropeptide receptor 0.0253 0.0615 0.2012
Schistosoma mansoni microtubule-associated protein tau 0.0704 0.1749 0.968
Brugia malayi GH02984p 0.0355 0.087 0.1272
Leishmania major eukaryotic initiation factor 4a, putative 0.0727 0.1807 1
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0111 0.0257 0.1411
Trypanosoma brucei RNA helicase, putative 0.0043 0.0087 0.0474
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0044 0.009 0.0295
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0012 0.0015
Entamoeba histolytica hypothetical protein 0.0016 0.002 0.0088
Trypanosoma cruzi oligopeptidase b 0.0009 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Leishmania major protein farnesyltransferase alpha subunit, putative 0.005 0.0105 0.0577
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0023 0.0036 0.019
Toxoplasma gondii protease inhibitor PI1 0.0012 0.0008 0.0006
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0096 0.0137
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0055 0.0052
Trypanosoma cruzi cytochrome P450, putative 0.001 0.0005 0.0027
Echinococcus multilocularis tubulin beta 1 chain 0.0123 0.0287 0.0939
Schistosoma mansoni integrin alpha-ps 0.0144 0.0341 0.1874
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.001 0.0005 0.0025
Brugia malayi ORL1-like opioid receptor 0.0253 0.0615 0.0898
Onchocerca volvulus Neuropeptide F receptor homolog 0.0253 0.0615 0.1866
Brugia malayi Integrin beta pat-3 precursor 0.0233 0.0564 0.0823
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0727 0.1807 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0253 0.0615 0.2012
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0012 0.0009 0.0065
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0011 0.0006 0.0009
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0253 0.0615 0.2012
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0071 0.0232
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0025 0.0041 0.0056
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0009 0.0002 0.0008
Mycobacterium leprae Probable lipase LipE 0.0037 0.0071 0.5887
Echinococcus multilocularis Zinc finger, RanBP2 type 0.001 0.0005 0.0015
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0727 0.1807 1
Echinococcus multilocularis metabotropic glutamate receptor 2 0.001 0.0004 0.0014
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Loa Loa (eye worm) hypothetical protein 0.0036 0.0069 0.01
Loa Loa (eye worm) G-protein coupled receptor 0.0253 0.0615 0.0901
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.001 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0041 0.0059
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0253 0.0615 0.2012
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0005 0.0003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0217 0.1191
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0079 0.0433
Echinococcus granulosus Estrogen regulated protein EP45 0.0012 0.0008 0.0028
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0109 0.0572
Schistosoma mansoni RNA binding protein 0.001 0.0005 0.0012
Brugia malayi hypothetical protein 0.0253 0.0615 0.0898
Onchocerca volvulus 0.0253 0.0615 0.1866
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0005 0.0012
Echinococcus granulosus neuropeptide Y receptor 0.0253 0.0615 0.2012
Schistosoma mansoni cpg binding protein 0.0012 0.0009 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Brugia malayi serpin 0.0012 0.0008 0.0009
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0011 0.0006 0.0019
Onchocerca volvulus 0.0037 0.0071 0.0204
Schistosoma mansoni hypothetical protein 0.002 0.0028 0.0144
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Trypanosoma brucei metacaspase MCA3 0.0015 0.0015 0.008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0253 0.0615 0.2012
Brugia malayi Serotonin receptor 0.0253 0.0615 0.0898
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0197 0.0474 0.0694
Echinococcus multilocularis glutamate receptor 2 0.0034 0.0065 0.0212
Trypanosoma brucei unspecified product 0.0027 0.0047 0.0254
Giardia lamblia Beta tubulin 0.0123 0.0287 0.1559
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Schistosoma mansoni hypothetical protein 0.0037 0.0071 0.0379
Echinococcus multilocularis peregrin 0.0033 0.0062 0.0203
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0037 0.0071 0.0381
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Brugia malayi YY1-associated factor 2 0.001 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Schistosoma mansoni caspase-3 (C14 family) 0.0015 0.0015 0.0072
Echinococcus multilocularis solute carrier family 5 0.0039 0.0077 0.0252
Leishmania major hypothetical protein, conserved 0.0072 0.0159 0.0874
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0037 0.0071 0.0068
Schistosoma mansoni hypothetical protein 0.0043 0.0087 0.0466
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0005 0.0012
Echinococcus multilocularis G protein coupled receptor 139 0.0253 0.0615 0.2012
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Loa Loa (eye worm) serpin 0.0012 0.0008 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0047 0.0254
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0071 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.002 0.0097
Loa Loa (eye worm) hypothetical protein 0.0037 0.0071 0.0104
Echinococcus multilocularis ring and YY1 binding protein 0.001 0.0005 0.0015
Schistosoma mansoni glutamate receptor AMPA 0.0034 0.0065 0.0345
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Entamoeba histolytica multidrug resistance protein, putative 0.0011 0.0007 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Brugia malayi G protein-coupled receptor 0.0253 0.0615 0.0898
Leishmania major cytochrome p450-like protein 0.001 0.0005 0.002
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0005 0.0001
Plasmodium falciparum cysteine proteinase falcipain 1 0.0023 0.0036 0.0186
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.0011 0.0006 0.0005
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0055 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.002 0.0097
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0051 0.0107 0.0551
Brugia malayi putative neuropeptide receptor NPR1 0.0253 0.0615 0.0898
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0005 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Brugia malayi GnHR receptor homolog 0.0253 0.0615 0.0898
Schistosoma mansoni coup transcription factor 0.001 0.0005 0.0012
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0253 0.0615 0.0901
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0024
Brugia malayi Sodium:solute symporter family protein 0.0039 0.0077 0.0109
Brugia malayi hypothetical protein 0.0253 0.0615 0.0898
Loa Loa (eye worm) integrin alpha pat-2 0.0144 0.0341 0.0499
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0072 0.0159 0.0867
Trypanosoma cruzi metacaspase, putative 0.0015 0.0015 0.0085
Echinococcus multilocularis somatostatin receptor 0.0253 0.0615 0.2012
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.005 0.0105 0.0345
Onchocerca volvulus 0.0028 0.0049 0.0136
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0079 0.0438
Entamoeba histolytica hypothetical protein 0.0016 0.002 0.0088
Entamoeba histolytica tubulin family protein 0.0123 0.0287 0.1569
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.0036 0.0195
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0005 0.0007
Onchocerca volvulus Ribonuclease H1 homolog 0.0011 0.0007 0.001
Onchocerca volvulus 0.0015 0.0017 0.0039
Loa Loa (eye worm) tubulin beta chain 0.0123 0.0287 0.042
Echinococcus granulosus hyperpolarization activated cyclic 0.0009 0.0002 0.0008
Entamoeba histolytica hypothetical protein 0.0011 0.0007 0.0013
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0029 0.0052 0.0271
Trypanosoma brucei DNA polymerase eta, putative 0.0065 0.0143 0.0786
Echinococcus granulosus glutamate receptor 2 0.0044 0.009 0.0295
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0727 0.1807 0.591
Echinococcus granulosus g protein coupled receptor 0.0253 0.0615 0.2012
Echinococcus granulosus neuropeptides capa receptor 0.0253 0.0615 0.2012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0005 0.0006
Loa Loa (eye worm) TYRA-2 protein 0.0253 0.0615 0.0901
Schistosoma mansoni caspase-7 (C14 family) 0.0056 0.0119 0.0648
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0067 0.0147 0.0793
Echinococcus granulosus phd:f box containing protein 0.001 0.0003 0.0009
Brugia malayi hypothetical protein 0.2723 0.6825 1
Trichomonas vaginalis elongin C protein, putative 0.0043 0.0086 0.0462
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0095 0.0217 0.1191
Schistosoma mansoni voltage-gated cation channel 0.001 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0005 0.0003
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.005 0.0105 0.0569
Entamoeba histolytica hypothetical protein 0.0037 0.0071 0.037
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0012 0.0009 0.0037
Loa Loa (eye worm) neuropeptide F receptor 0.0253 0.0615 0.0901
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0012
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0099 0.0226 0.074
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0015 0.0072
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0727 0.1807 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.0285 0.0417
Schistosoma mansoni neuropeptide receptor 0.0253 0.0615 0.3395
Echinococcus granulosus ribonuclease H1 0.0011 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Trypanosoma cruzi cruzipain precursor, putative 0.0015 0.0016 0.0086
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0071 0.0393
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0071 0.038
Echinococcus granulosus beta tubulin 0.0123 0.0287 0.0939
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0122 0.0285 0.1565
Schistosoma mansoni integrin beta subunit 0.0137 0.0323 0.1777
Echinococcus multilocularis p2X purinoceptor 4 0.0099 0.0227 0.0742
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0005 0.0015
Echinococcus multilocularis hyperpolarization activated cyclic 0.0009 0.0002 0.0008
Echinococcus granulosus cathepsin L cysteine proteinase 0.0044 0.009 0.0296
Leishmania major hypothetical protein, conserved 0.001 0.0003 0.0008
Brugia malayi serpin 0.0012 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0013 0.0012 0.0017
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.001 0.0004 0.0006
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0015 0.0015 0.0019
Echinococcus granulosus atrial natriuretic peptide receptor 0.001 0.0004 0.0014
Onchocerca volvulus 0.0253 0.0615 0.1866
Brugia malayi hypoxia-induced factor 1 0.0015 0.0015 0.0019
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0012 0.0009 0.0681
Loa Loa (eye worm) hypothetical protein 0.01 0.0229 0.0336
Loa Loa (eye worm) solute carrier family 6 member 4 0.0028 0.0049 0.0071
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0071 0.0379
Echinococcus granulosus hyperpolarization activated cyclic 0.0009 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0006
Trypanosoma brucei metacaspase MCA2 0.0015 0.0015 0.008
Schistosoma mansoni inositol transporter 0.0039 0.0077 0.0413
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0009 0.0001 0.0005
Toxoplasma gondii hypothetical protein 0.005 0.0105 0.0103
Brugia malayi hypothetical protein 0.002 0.0028 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Loa Loa (eye worm) serotonin transporter b 0.0028 0.0049 0.0071
Schistosoma mansoni hypothetical protein 0.001 0.0003 0.0003
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0039 0.0077 0.0252
Echinococcus granulosus inhibitor of apoptosis protein 0.0096 0.022 0.072
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.001 0.0003 0.0011
Entamoeba histolytica ATP-binding cassette protein, putative 0.0011 0.0007 0.0013
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.001 0.0005 0.017
Echinococcus granulosus p2X purinoceptor 4 0.0099 0.0227 0.0742
Echinococcus granulosus cathepsin L 0.0023 0.0036 0.0118
Echinococcus granulosus geminin 0.0198 0.0477 0.156
Chlamydia trachomatis glutamine binding protein 0.0051 0.0107 0.3266
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.0011 0.0006 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0036 0.0178
Leishmania major ribonuclease H1, putative 0.0011 0.0007 0.0034
Schistosoma mansoni phosphatidylserine receptor 0.001 0.0003 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0023 0.0036 0.0049
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.001 0.0003 0.0011
Schistosoma mansoni serpin 0.0012 0.0008 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0055 0.0305
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0069 0.0226
Onchocerca volvulus 0.0044 0.009 0.0264
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0071 0.0104
Brugia malayi Dopamine receptor 0.0253 0.0615 0.0898
Loa Loa (eye worm) oxidoreductase 0.0012 0.0009 0.0013
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0078 0.011
Echinococcus multilocularis allatostatin A receptor 0.0253 0.0615 0.2012
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0071 0.0103
Echinococcus granulosus nmda type glutamate receptor 0.0071 0.0156 0.0512
Trypanosoma brucei beta tubulin 0.0123 0.0287 0.1584
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0003 0.0004
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.0569 0.3143
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0011 0.0006 0.0009
Echinococcus granulosus g protein coupled receptor 0.0253 0.0615 0.2012
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0012 0.0009 0.0052
Toxoplasma gondii ribonuclease HI protein 0.0011 0.0007 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0015 0.0072
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0011 0.0006 0.0009
Echinococcus multilocularis Tubulin beta 2C chain 0.0123 0.0287 0.0939
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0085 0.0279
Echinococcus granulosus ring and YY1 binding protein 0.001 0.0005 0.0015
Plasmodium falciparum eukaryotic initiation factor 4A 0.0727 0.1807 1
Entamoeba histolytica cysteine proteinase, putative 0.0044 0.009 0.0478
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0111 0.0257 0.0841
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0071 0.038
Loa Loa (eye worm) hypothetical protein 0.2723 0.6825 1
Onchocerca volvulus 0.0253 0.0615 0.1866
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Trypanosoma brucei prolyl oligopeptidase, putative 0.0009 0.0001 0.0002
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0035 0.0067 0.0098
Echinococcus multilocularis Tubulin beta 2C chain 0.0123 0.0287 0.0939
Schistosoma mansoni P2X receptor subunit 0.0099 0.0227 0.1244
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0011 0.0006 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0253 0.0615 0.3395
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0005 0.0003
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0009 0.0373
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0098
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0023 0.0036 0.0116
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0005 0.0003
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0075 0.0413
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.002 0.0028 0.0093
Trypanosoma cruzi ribonuclease H1, putative 0.0011 0.0007 0.0041
Brugia malayi Cathepsin L-like precursor 0.0044 0.009 0.0129
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0078 0.043
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0053 0.0273
Trichomonas vaginalis tubulin beta chain, putative 0.0123 0.0287 0.1577
Echinococcus granulosus tm gpcr rhodopsin 0.1225 0.3057 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Schistosoma mansoni metabotropic glutamate receptor 0.001 0.0004 0.001
Loa Loa (eye worm) RGC/RGC protein kinase 0.001 0.0004 0.0006
Giardia lamblia Rab geranylgeranyltransferase 0.0122 0.0285 0.1548
Trypanosoma cruzi cysteine protease, putative 0.0023 0.0036 0.02
Brugia malayi eukaryotic initiation factor 4A 0.0727 0.1807 0.2645
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.04 0.0984 0.5439
Schistosoma mansoni glutamate receptor kainate 0.0034 0.0065 0.0345
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Schistosoma mansoni biogenic amine receptor 0.0253 0.0615 0.3395
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0096 0.022 0.072
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0005 0.0003
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0005 0.0003
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0253 0.0615 0.0901
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0003
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0089 0.0202 0.1104
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0009 0.0002 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0047 0.0254
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0111 0.0257 0.141
Onchocerca volvulus 0.0253 0.0615 0.1866
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0095 0.0217 0.0315
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0005 0.0015
Echinococcus granulosus microtubule associated protein 2 0.0704 0.1749 0.5721
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0015 0.0015 0.0072
Plasmodium falciparum M17 leucyl aminopeptidase 0.0033 0.0062 0.033
Onchocerca volvulus 0.0096 0.022 0.0659
Giardia lamblia Ribonuclease H 0.0011 0.0007 0.0006
Echinococcus multilocularis neuropeptide receptor 0.0253 0.0615 0.2012
Schistosoma mansoni jumonji domain containing protein 0.001 0.0003 0.0002
Echinococcus granulosus zinc finger protein Ran binding 0.001 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Echinococcus granulosus Nuclear pore complex protein Nup153 0.001 0.0005 0.0015
Echinococcus multilocularis inhibitor of apoptosis protein 0.0096 0.022 0.072
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0078 0.0175 0.0257
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0071 0.0232
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0071 0.0232
Schistosoma mansoni tyrosine kinase 0.001 0.0004 0.001
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0253 0.0615 0.2012
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0005 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0036 0.0178
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.001 0.0003 0.0011
Trypanosoma brucei metacaspase 5, putative 0.0015 0.0015 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0015 0.0015 0.0072
Echinococcus multilocularis caspase 2 0.0056 0.0119 0.039
Echinococcus multilocularis cpg binding protein 0.0013 0.0011 0.0037
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0044 0.009 0.0486
Leishmania major cathepsin L-like protease 0.0044 0.009 0.0494
Trypanosoma brucei beta tubulin 0.0123 0.0287 0.1584
Giardia lamblia Rab geranylgeranyltransferase 0.005 0.0105 0.0551
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0023 0.0036 0.02
Brugia malayi Trypsin-like protease protein 5 0.0095 0.0217 0.0315
Schistosoma mansoni cathepsin F (C01 family) 0.003 0.0053 0.0283
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.005 0.0105 0.0583
Trypanosoma cruzi ribonuclease H1, putative 0.0011 0.0007 0.0041
Brugia malayi serpin 0.0012 0.0008 0.0009
Schistosoma mansoni glutamate receptor kainate 0.0034 0.0065 0.0345
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.001 0.0003 0.0011
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0122 0.0285 0.1565
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0007
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0253 0.0615 0.3395
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Echinococcus granulosus glutamate receptor subunit protein glur 0.002 0.0028 0.0093
Chlamydia trachomatis cytosol aminopeptidase 0.0056 0.012 0.3707
Echinococcus granulosus neuropeptide receptor A26 0.0253 0.0615 0.2012
Echinococcus multilocularis integrin alpha ps 0.0244 0.0591 0.1935
Schistosoma mansoni fusion 0.001 0.0005 0.0012
Brugia malayi Tachykinin-like peptides receptor 99D 0.0253 0.0615 0.0898
Brugia malayi hypothetical protein 0.0253 0.0615 0.0898
Loa Loa (eye worm) hypothetical protein 0.0037 0.0073 0.0106
Leishmania major pteridine reductase 1 0.0011 0.0007 0.003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0078 0.0419
Leishmania major cathepsin L-like protease 0.0062 0.0136 0.0744
Loa Loa (eye worm) ELC-1 protein 0.0043 0.0086 0.0125
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0096 0.0518
Schistosoma mansoni tsg101-related 0.0082 0.0185 0.1011
Echinococcus multilocularis tissue type plasminogen activator 0.0072 0.0159 0.052
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0012 0.0009 0.0045
Echinococcus multilocularis JmjC domain containing protein 4 0.001 0.0003 0.0009
Toxoplasma gondii ABC1 family protein 0.0037 0.0071 0.0068
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Brugia malayi Kringle domain containing protein 0.0072 0.0159 0.023
Echinococcus granulosus serotonin transporter 0.0028 0.0049 0.0159
Loa Loa (eye worm) trypsin family protein 0.0095 0.0217 0.0318
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Brugia malayi larval opioid receptor 0.0253 0.0615 0.0898
Echinococcus granulosus glycoprotein Antigen 5 0.0095 0.0217 0.0711
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0727 0.1807 1
Plasmodium falciparum beta-hydroxyacyl-ACP dehydratase 0.0131 0.0307 0.1686
Echinococcus multilocularis elongin b 0.0197 0.0474 0.1551
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0136 0.075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Loa Loa (eye worm) tubulin beta-4 chain 0.0123 0.0287 0.042
Leishmania major cysteine peptidase A (CPA) 0.0044 0.009 0.0494
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0071 0.0156 0.0512
Echinococcus granulosus cpg binding protein 0.0013 0.0011 0.0037
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0009 0.0002 0.0008
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0015 0.0017 0.008
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0003 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0071 0.038
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0011 0.0006 0.0009
Echinococcus granulosus SWI:SNF matrix associated 0.0029 0.0052 0.0169
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0011 0.0006 0.0009
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0039 0.0077 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Toxoplasma gondii beta-1 tubulin, putative 0.0123 0.0287 0.0284
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0048
Schistosoma mansoni cellular tumor antigen P53 0.0037 0.0073 0.039
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.008 0.0179 0.0586
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.002 0.003 0.0157
Echinococcus granulosus p2X purinoceptor 4 0.0099 0.0227 0.0742
Entamoeba histolytica cysteine proteinase 1, putative 0.0023 0.0036 0.0178
Toxoplasma gondii kringle domain-containing protein 0.0072 0.0159 0.0156
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.001 0.0005 0.0003
Onchocerca volvulus 0.0012 0.0008 0.0013
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0011 0.0006 0.0032
Echinococcus granulosus Tubulin beta 2C chain 0.0123 0.0287 0.0939
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0005 0.0006
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0099 0.0226 0.074
Schistosoma mansoni hypothetical protein 0.0043 0.0086 0.0462
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0005 0.0015
Onchocerca volvulus Cell death protein 3 homolog 0.0056 0.0119 0.0352
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0071 0.0378
Onchocerca volvulus Cathepsin L homolog 0.0044 0.009 0.0264
Schistosoma mansoni opsin-like receptor 0.0253 0.0615 0.3395
Echinococcus multilocularis NMDA receptor 0.002 0.0028 0.0093
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0044 0.009 0.0486
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0015 0.0017 0.008
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0056 0.012 0.3748
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0169 0.0403 0.0587
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0011 0.0007 0.0004
Brugia malayi cathepsin L-like precursor 0.003 0.0053 0.0075
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0253 0.0615 0.3395
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0217 0.1191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0005 0.0006
Echinococcus multilocularis neuropeptide s receptor 0.0253 0.0615 0.2012
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0078 0.0254
Schistosoma mansoni amine GPCR 0.0253 0.0615 0.3395
Mycobacterium tuberculosis Probable oxidoreductase 0.0011 0.0007 0.003
Schistosoma mansoni multidrug resistance protein 0.0011 0.0007 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.009 0.0488
Echinococcus multilocularis prolyl endopeptidase 0.0023 0.0036 0.0116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0075 0.0072
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0012 0.0009 0.003
Echinococcus granulosus Estrogen regulated protein EP45 0.0012 0.0008 0.0028
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0022
Schistosoma mansoni hypothetical protein 0.0025 0.0041 0.0213
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0005 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.009 0.05
Loa Loa (eye worm) hypothetical protein 0.2593 0.6496 0.9518
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.001 0.0004 0.0015
Schistosoma mansoni amine GPCR 0.0528 0.1305 0.7221
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0015 0.0015 0.0013
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0015 0.0015 0.005
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0029 0.0052 0.0049
Schistosoma mansoni opsin-like receptor 0.0253 0.0615 0.3395
Echinococcus granulosus dna polymerase kappa 0.0039 0.0078 0.0254
Loa Loa (eye worm) hypothetical protein 0.0099 0.0226 0.0331
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.005 0.0105 0.0345
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0037 0.0071 0.0381
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0033 0.0062 0.0344
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0006
Echinococcus multilocularis serotonin transporter 0.0028 0.0049 0.0159
Loa Loa (eye worm) glutamate receptor 1 0.0034 0.0065 0.0094
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Brugia malayi hypothetical protein 0.0012 0.0008 0.0009
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.001 0.0005 0.0003
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0109 0.0599
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0012 0.0009 0.0037
Schistosoma mansoni high-affinity choline transporter 0.0355 0.087 0.481
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0005 0.0015
Mycobacterium ulcerans hypothetical protein 0.0095 0.0217 1
Schistosoma mansoni thyroid hormone receptor 0.001 0.0005 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Echinococcus granulosus p2X purinoceptor 4 0.0099 0.0227 0.0742
Echinococcus multilocularis ribonuclease H1 0.0011 0.0007 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0044 0.009 0.0488
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0122 0.0285 0.1564
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0009 0.0007
Plasmodium vivax unspecified product 0.0015 0.0016 0.0071
Loa Loa (eye worm) hypothetical protein 0.0037 0.0071 0.0104
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0071 0.0386
Loa Loa (eye worm) tubulin beta-2A chain 0.0123 0.0287 0.042
Schistosoma mansoni tsg101-related 0.0067 0.0147 0.0802
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0009 0.0373
Echinococcus granulosus serine protease inhibitor 0.0012 0.0008 0.0028
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0005 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0036 0.0187
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0095 0.0217 0.0711
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0044 0.009 0.0296
Loa Loa (eye worm) neuropeptide F receptor 0.0253 0.0615 0.0901
Schistosoma mansoni neuropeptide receptor 0.0253 0.0615 0.3395
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Schistosoma mansoni amine GPCR 0.0253 0.0615 0.3395
Trypanosoma cruzi lanosterol synthase, putative 0.0093 0.0213 0.1181
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0096 0.0314
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0053 0.0078
Loa Loa (eye worm) hypothetical protein 0.0044 0.009 0.0132
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0005 0.0012
Giardia lamblia Multidrug resistance-associated protein 1 0.0011 0.0007 0.0002
Brugia malayi follicle stimulating hormone receptor 0.0253 0.0615 0.0898
Trichomonas vaginalis hypothetical protein 0.0048 0.0099 0.0537
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0005 0.0003
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0015 0.0015 0.0072
Brugia malayi hypothetical protein 0.0041 0.0083 0.0117
Schistosoma mansoni phosphoglucomutase 0.0011 0.0007 0.0027
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0253 0.0615 0.2012
Brugia malayi Integrin alpha pat-2 precursor 0.0144 0.0341 0.0496
Echinococcus multilocularis nmda type glutamate receptor 0.001 0.0004 0.0014
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0071 0.0379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0036 0.0187
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0071
Echinococcus multilocularis fmrfamide receptor 0.0253 0.0615 0.2012
Giardia lamblia Beta tubulin 0.0123 0.0287 0.1559
Mycobacterium ulcerans oxidoreductase 0.0012 0.0009 0.0373
Mycobacterium tuberculosis Conserved protein 0.0037 0.0071 0.0386
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.001 0.0005 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0005 0.0012
Echinococcus multilocularis receptor type guanylyl cyclase 0.001 0.0004 0.0014
Brugia malayi hypothetical protein 0.0253 0.0615 0.0898
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0047 0.0254
Echinococcus multilocularis neuropeptide Y receptor 0.0253 0.0615 0.2012
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0023 0.0036 0.0184
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0096 0.022 0.072
Echinococcus multilocularis Estrogen regulated protein EP45 0.0012 0.0008 0.0028
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0023 0.0036 0.0184
Echinococcus multilocularis integrin alpha 3 0.0069 0.0152 0.0497
Brugia malayi hypothetical protein 0.0037 0.0071 0.01
Onchocerca volvulus 0.0253 0.0615 0.1866
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0055 0.03
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0253 0.0615 0.3395
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0253 0.0615 0.3395
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.001 0.0005 0.0025
Schistosoma mansoni P2X receptor subunit 0.0099 0.0227 0.1244
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0012 0.0009 0.0052
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0044 0.009 0.0295
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1375 0.3436 0.5034
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0029 0.0052 0.0049
Echinococcus granulosus allatostatin A receptor 0.0253 0.0615 0.2012
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0122 0.0285 0.0414
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0005 0.0012
Trypanosoma cruzi lanosterol synthase, putative 0.0093 0.0213 0.1181
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.0012 0.0039
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0005 0.0015
Trypanosoma brucei oxidoreductase-like protein 0.0011 0.0007 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.0036 0.0195
Loa Loa (eye worm) hypothetical protein 0.04 0.0984 0.1441
Entamoeba histolytica hypothetical protein 0.0016 0.002 0.0088
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0071 0.0386
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0253 0.0615 0.3395
Onchocerca volvulus 0.0016 0.0019 0.0046
Echinococcus granulosus G protein coupled receptor 139 0.0253 0.0615 0.2012
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0082 0.0443
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Leishmania major cathepsin L-like protease 0.0044 0.009 0.0494
Schistosoma mansoni zinc finger protein 0.001 0.0005 0.0012
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.005 0.0105 0.0571
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0005 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.0028 0.0049 0.0257
Onchocerca volvulus 0.0253 0.0615 0.1866
Echinococcus granulosus rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0009 0.001
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.001 0.0003 0.001
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.009 0.0204 0.112
Echinococcus multilocularis fmrfamide receptor 0.0253 0.0615 0.2012
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0051 0.0107 0.3266
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0078 0.0423
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0727 0.1807 1
Schistosoma mansoni brg-1 associated factor 0.0029 0.0052 0.0273
Trypanosoma cruzi DNA polymerase eta, putative 0.0065 0.0143 0.0791
Loa Loa (eye worm) hypothetical protein 0.0072 0.0159 0.0233
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0011 0.0007 0.0029
Echinococcus granulosus peptide allatostatin:somatostatin 0.0253 0.0615 0.2012
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0083 0.027
Plasmodium vivax vivapain-2 0.0044 0.009 0.0486
Echinococcus multilocularis metabotropic glutamate receptor 5 0.001 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0082 0.0443
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0005 0.0003
Schistosoma mansoni amine GPCR 0.0253 0.0615 0.3395
Schistosoma mansoni biogenic amine receptor 0.0253 0.0615 0.3395
Leishmania major hypothetical protein, conserved 0.001 0.0005 0.0018
Echinococcus multilocularis high affinity choline transporter 1 0.0355 0.087 0.2847
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0051 0.0107 0.0551
Onchocerca volvulus Putative nachr subunit 0.0023 0.0036 0.0096
Echinococcus multilocularis dna polymerase eta 0.0065 0.0143 0.0468
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0253 0.0615 0.0901
Schistosoma mansoni glutamate receptor NMDA 0.0044 0.009 0.0487
Brugia malayi Latrophilin receptor protein 2 0.0025 0.0041 0.0056
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0051 0.0107 0.0583
Echinococcus multilocularis phd:f box containing protein 0.001 0.0003 0.0009
Onchocerca volvulus 0.0253 0.0615 0.1866
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0009 0.0373
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Schistosoma mansoni hypothetical protein 0.0198 0.0477 0.263
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0095 0.0512
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0033 0.0062 0.0344
Schistosoma mansoni cathepsin s 0.0015 0.0016 0.0073
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0078
Leishmania major p-glycoprotein e 0.0011 0.0007 0.0029
Schistosoma mansoni tubulin subunit beta 0.0123 0.0287 0.1577
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0253 0.0615 0.2012
Echinococcus granulosus cathepsin l1 0.0044 0.009 0.0296
Schistosoma mansoni survival motor neuron protein 0.0049 0.0102 0.0554
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0037 0.0071 0.0101
Mycobacterium ulcerans beta-lactamase 0.0037 0.0071 0.3225
Echinococcus multilocularis beta tubulin 0.0123 0.0287 0.0939
Trichomonas vaginalis tubulin alpha chain, putative 0.0123 0.0287 0.1577
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0253 0.0615 0.2012
Schistosoma mansoni tubulin subunit beta 0.0123 0.0287 0.1577
Schistosoma mansoni hypothetical protein 0.0096 0.022 0.1206
Echinococcus multilocularis neuropeptides capa receptor 0.0253 0.0615 0.2012
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0022 0.0124
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0217 0.1191
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0053 0.0282
Plasmodium falciparum metacaspase 1 0.0015 0.0015 0.007
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus multilocularis integrin beta 2 0.0172 0.0412 0.1347
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0005 0.0015
Onchocerca volvulus 0.0253 0.0615 0.1866
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0253 0.0615 0.2012
Brugia malayi Cathepsin L-like precursor 0.0044 0.009 0.0129
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0005 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0159 0.088
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.001 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0054 0.0113 0.0614
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0078 0.3533
Brugia malayi AKH receptor 0.0253 0.0615 0.0898
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0253 0.0615 0.3395
Onchocerca volvulus 0.0095 0.0217 0.0651
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0015 0.0015 0.0072
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.0011 0.0046
Plasmodium vivax beta-hydroxyacyl-ACP dehydratase precursor, putative 0.0131 0.0307 0.1686
Echinococcus granulosus glutamate receptor ionotropic kainate 0.002 0.0028 0.0093
Brugia malayi SWIB/MDM2 domain containing protein 0.0029 0.0052 0.0072
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0009 0.0373
Onchocerca volvulus 0.0037 0.0071 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0052 0.0273
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.0585 0.1914
Echinococcus granulosus hypothetical protein 0.0253 0.0615 0.2012
Echinococcus multilocularis g protein coupled receptor 0.0253 0.0615 0.2012
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0727 0.1807 1
Echinococcus granulosus tm gpcr rhodopsin 0.0253 0.0615 0.2012
Onchocerca volvulus 0.0012 0.0008 0.0013
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0111 0.0257 0.0841
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0009 0.0002 0.0008
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0109 0.0605
Brugia malayi Melatonin receptor type 1A 0.0253 0.0615 0.0898
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0096 0.0314
Echinococcus granulosus tissue type plasminogen activator 0.0072 0.0159 0.052
Brugia malayi transcription elongation factor B polypeptide 1, putative 0.0043 0.0086 0.0122
Echinococcus multilocularis sex peptide receptor 0.0253 0.0615 0.2012
Onchocerca volvulus 0.0039 0.0077 0.0222
Loa Loa (eye worm) serpin 0.0012 0.0008 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0109 0.0592
Echinococcus granulosus multidrug resistance associated protein 1 0.0011 0.0007 0.0021
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0071 0.0386
Loa Loa (eye worm) hypothetical protein 0.0056 0.0119 0.0174
Echinococcus multilocularis multidrug resistance associated protein 7 0.0011 0.0007 0.0021
Echinococcus multilocularis caspase 0.0015 0.0015 0.005
Echinococcus multilocularis integrin alpha ps 0.0069 0.0152 0.0497
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0005 0.0012
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0011 0.0007 0.0029
Onchocerca volvulus Alhambra homolog 0.003 0.0053 0.015
Plasmodium vivax vivapain-3 0.0023 0.0036 0.0186
Echinococcus multilocularis p2X purinoceptor 4 0.0099 0.0227 0.0742
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0028 0.0049 0.0068
Entamoeba histolytica hypothetical protein 0.0043 0.0086 0.0453
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0015 0.0015 0.0072
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0109 0.0592
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.005 0.0105 0.0345
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.001 0.0003 0.0011
Brugia malayi Metabotropic glutamate receptor precursor. 0.001 0.0004 0.0003
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0078 0.0254
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0023 0.0036 0.0187
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0052 0.0271
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.005 0.0105 0.0583
Loa Loa (eye worm) glutamate receptor 2 0.0034 0.0065 0.0094
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0727 0.1807 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1185 0.2959 0.9677
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0071
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0253 0.0615 0.2012
Onchocerca volvulus 0.0012 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0075 0.0167 0.0244
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0096 0.022 0.0319
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0011 0.0006 0.0032
Onchocerca volvulus 0.0015 0.0017 0.0039
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0009 0.0037
Echinococcus granulosus nmda type glutamate receptor 0.001 0.0004 0.0014
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0011 0.0006 0.0019
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0217 0.0711
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.005 0.0105 0.0569
Echinococcus granulosus tubulin beta 1 chain 0.0123 0.0287 0.0939
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Brugia malayi ImpB/MucB/SamB family protein 0.0065 0.0143 0.0206
Echinococcus granulosus tubulin beta 4A class IVa 0.0123 0.0287 0.0939
Plasmodium vivax vivapain-2 0.0044 0.009 0.0486
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Onchocerca volvulus 0.0253 0.0615 0.1866
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0044 0.009 0.0295
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.009 0.0488
Onchocerca volvulus 0.0253 0.0615 0.1866
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0078 0.043
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0071 0.0394
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0023 0.0036 0.0116
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0012 0.0009 0.0045
Schistosoma mansoni inositol transporter 0.0039 0.0077 0.0413
Onchocerca volvulus 0.0012 0.0009 0.0016
Schistosoma mansoni hypothetical protein 0.0253 0.0615 0.3395
Echinococcus granulosus 7tm_1 domain containing protein 0.0253 0.0615 0.2012
Brugia malayi metabotropic glutamate receptor type 2 0.001 0.0004 0.0003
Loa Loa (eye worm) CYP4Cod1 0.001 0.0005 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0071 0.0393
Trypanosoma cruzi protein farnesyltransferase, putative 0.0111 0.0257 0.1423
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0071 0.3225
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0111 0.0257 0.1411
Echinococcus granulosus Tubulin beta 2C chain 0.0123 0.0287 0.0939
Brugia malayi Receptor family ligand binding region containing protein 0.001 0.0004 0.0003
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0253 0.0615 0.3395
Echinococcus granulosus dna polymerase eta 0.0065 0.0143 0.0468
Echinococcus granulosus GPCR family 2 0.0025 0.0041 0.0134
Toxoplasma gondii prolyl endopeptidase 0.0023 0.0036 0.0033
Brugia malayi sulfakinin receptor protein 0.0298 0.0729 0.1065
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0089 0.0202 0.0659
Loa Loa (eye worm) norepinephrine transporter 0.0028 0.0049 0.0071
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0078 0.0407
Schistosoma mansoni cathepsin F (C01 family) 0.0044 0.009 0.0488
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.005 0.0105 0.0578
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0082 0.008
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0253 0.0615 0.0898
Schistosoma mansoni histamine h1 receptor 0.0253 0.0615 0.3395
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0009 0.0002 0.0008
Wolbachia endosymbiont of Brugia malayi (3R)-hydroxymyristoyl-ACP dehydratase 0.0131 0.0307 1
Schistosoma mansoni protein kinase 0.001 0.0004 0.001
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0003 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.009 0.0488
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0009 0.0002 0.0008
Brugia malayi Trypsin family protein 0.0095 0.0217 0.0315
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0071 0.0386
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus granulosus caspase 0.0015 0.0015 0.005
Echinococcus multilocularis SWI:SNF matrix associated 0.0029 0.0052 0.0169
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0012 0.001 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0022 0.0124
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0056 0.012 1
Echinococcus multilocularis p2X purinoceptor 4 0.0099 0.0227 0.0742
Echinococcus multilocularis G-protein coupled receptor, putative 0.0253 0.0615 0.2012
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0053 0.0283
Brugia malayi hypothetical protein 0.0095 0.0217 0.0315
Plasmodium vivax metacaspase 1, putative 0.0015 0.0015 0.007
Onchocerca volvulus 0.0253 0.0615 0.1866
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.001 0.0003 0.0015
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0023 0.0036 0.0116
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0136 0.075
Brugia malayi metabotropic GABA-B receptor subtype 2 0.001 0.0004 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Onchocerca volvulus 0.0044 0.009 0.0264
Loa Loa (eye worm) hypoxia-induced factor 1 0.0015 0.0015 0.0022
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0224 0.0731
Loa Loa (eye worm) RGC/RGC protein kinase 0.001 0.0004 0.0006
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0119
Brugia malayi latrophilin 2 splice variant baaae 0.0054 0.0113 0.0162
Onchocerca volvulus 0.0253 0.0615 0.1866
Echinococcus granulosus glutamate receptor 2 0.0025 0.004 0.0132
Echinococcus granulosus neuropeptide FF receptor 2 0.0253 0.0615 0.2012
Schistosoma mansoni hypothetical protein 0.0025 0.0041 0.0213
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0111 0.0257 0.1403
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0253 0.0615 0.1866
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0253 0.0615 0.3395
Schistosoma mansoni TRABID protein (C64 family) 0.001 0.0005 0.0012
Loa Loa (eye worm) brahma associated protein 0.0029 0.0052 0.0075
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Schistosoma mansoni neuropeptide receptor 0.0253 0.0615 0.3395
Loa Loa (eye worm) hypothetical protein 0.04 0.0984 0.1441
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0109 0.0605
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0006
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0253 0.0615 0.3395
Leishmania major hypothetical protein, conserved 0.001 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0006
Giardia lamblia ABC transporter, putative 0.0011 0.0007 0.0002
Echinococcus granulosus lysine specific demethylase 6a 0.001 0.0003 0.0009
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0122 0.0285 0.1564
Echinococcus granulosus protein prenyltransferase alpha subunit 0.005 0.0105 0.0345
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.0011 0.0006 0.0017
Echinococcus granulosus multidrug resistance associated protein 7 0.0011 0.0007 0.0021
Schistosoma mansoni phosphoglucomutase 0.0011 0.0007 0.0027
Echinococcus granulosus Zinc finger RanBP2 type 0.001 0.0005 0.0015
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0071 0.0386
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0331 0.0482
Brugia malayi BmSERPIN 0.0012 0.0008 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.0585 0.1914
Brugia malayi Cell death protein 3 precursor 0.0056 0.0119 0.0171
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0011 0.0007 0.0009
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0036 0.0116
Schistosoma mansoni cpg binding protein 0.0013 0.0011 0.0049
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0009 0.0001 0.0005
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0071 0.0158 0.0863
Plasmodium vivax hypothetical protein, conserved 0.003 0.0053 0.0281
Leishmania major hypothetical protein, conserved 0.001 0.0005 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.009 0.0488
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.009 0.0488
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0029 0.0052 0.0169
Echinococcus multilocularis tumor protein p63 0.0256 0.0622 0.2036
Trypanosoma cruzi oligopeptidase b 0.0009 0.0001 0.0007
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Giardia lamblia Serpin 1 0.0012 0.0008 0.0012
Onchocerca volvulus 0.0253 0.0615 0.1866
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0253 0.0615 0.0898
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0009
Schistosoma mansoni neuropeptide receptor 0.0253 0.0615 0.3395
Loa Loa (eye worm) serpin 0.0012 0.0008 0.0012
Echinococcus multilocularis neuropeptides capa receptor 0.0253 0.0615 0.2012
Onchocerca volvulus 0.0044 0.009 0.0264
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0011 0.0007 0.0031
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0253 0.0615 0.3395
Brugia malayi Dopamine receptor protein 1 0.0253 0.0615 0.0898
Onchocerca volvulus 0.0095 0.0217 0.0651
Onchocerca volvulus 0.0095 0.0217 0.0651
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0005 0.0015
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0012
Giardia lamblia PHD finger protein 15 0.003 0.0053 0.0262
Brugia malayi Dopamine receptor protein 2 0.0253 0.0615 0.0898
Onchocerca volvulus 0.0044 0.009 0.0264
Echinococcus granulosus high affinity choline transporter 1 0.0355 0.087 0.2847
Echinococcus multilocularis neuropeptide receptor 0.0253 0.0615 0.2012
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0005 0.0003
Schistosoma mansoni protein phosphatase-2b 0.0011 0.0006 0.0019
Trypanosoma brucei ingi protein (ORF1) 0.0012 0.001 0.0049
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0005 0.0006
Onchocerca volvulus 0.0012 0.0008 0.0013
Schistosoma mansoni serine protease inhibitors serpins 0.0012 0.0008 0.0034
Trypanosoma cruzi beta tubulin, putative 0.0123 0.0287 0.1588
Onchocerca volvulus 0.0044 0.009 0.0264
Loa Loa (eye worm) hypothetical protein 0.0175 0.0418 0.0612
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0009 0.0052
Brugia malayi neuropeptide F receptor 0.0253 0.0615 0.0898
Brugia malayi brahma associated protein 60 kDa 0.0029 0.0052 0.0072
Echinococcus granulosus neuropeptide s receptor 0.0253 0.0615 0.2012
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0082 0.0441
Echinococcus granulosus metabotropic glutamate receptor 5 0.001 0.0004 0.0014
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0095 0.0512
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.005 0.0105 0.0154
Entamoeba histolytica cysteine protease, putative 0.0023 0.0036 0.0178
Leishmania major cathepsin L-like protease 0.0062 0.0136 0.0744
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0109 0.0605
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.001 0.0005 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0105 0.0583
Leishmania major hypothetical protein, conserved 0.0032 0.0058 0.0313
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.0112
Schistosoma mansoni adenoreceptor 0.0253 0.0615 0.3395
Echinococcus granulosus sodium:glucose cotransporter 2 0.0039 0.0077 0.0252
Giardia lamblia Multidrug resistance-associated protein 1 0.0011 0.0007 0.0002
Schistosoma mansoni alpha-1 adrenergic receptor 0.0253 0.0615 0.3395
Schistosoma mansoni inhibitor of apoptosis protein 0.0096 0.022 0.1206
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0009
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0025 0.0041 0.0134
Brugia malayi MH2 domain containing protein 0.0089 0.0201 0.0291
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0015 0.0015 0.0072
Loa Loa (eye worm) acetyltransferase 0.014 0.0331 0.0485
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0011 0.0007 0.0031
Echinococcus granulosus serine protease inhibitor 0.0012 0.0008 0.0028
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0253 0.0615 0.0898
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0083 0.027
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0033 0.0062 0.0339
Loa Loa (eye worm) G-protein coupled receptor 0.0253 0.0615 0.0901
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0012
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0009 0.0002 0.0008
Onchocerca volvulus 0.0253 0.0615 0.1866
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0253 0.0615 0.3395
Schistosoma mansoni neuropeptide F-like receptor 0.0253 0.0615 0.3395
Loa Loa (eye worm) CXXC zinc finger family protein 0.0012 0.0009 0.0013
Onchocerca volvulus 0.0305 0.0745 0.2263
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0078 0.0423
Echinococcus granulosus fmrfamide receptor 0.0253 0.0615 0.2012
Onchocerca volvulus 0.001 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0006
Toxoplasma gondii beta-hydroxyacyl-acyl carrier protein dehydratase (FABZ) 0.0131 0.0307 0.0304
Schistosoma mansoni hypothetical protein 0.0072 0.0159 0.0868
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0253 0.0615 0.0901
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0005 0.0015
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.0036 0.02
Echinococcus multilocularis hyperpolarization activated cyclic 0.0009 0.0002 0.0008
Schistosoma mansoni cpg binding protein 0.0013 0.0011 0.0049
Echinococcus granulosus peregrin 0.0033 0.0062 0.0203
Echinococcus multilocularis orexin receptor type 2 0.0253 0.0615 0.2012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0052
Schistosoma mansoni tyrosine kinase 0.001 0.0004 0.001
Trichomonas vaginalis tubulin epsilon chain, putative 0.0123 0.0287 0.1577
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0078 0.043
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0096 0.022 0.0319
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0009 0.0002 0.0003
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0023 0.0036 0.0187
Echinococcus granulosus integrin alpha ps 0.0244 0.0591 0.1935
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0109 0.0358
Brugia malayi serpin precursor 0.0012 0.0008 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Brugia malayi Cytochrome P450 family protein 0.0021 0.0031 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0044 0.009 0.0488
Brugia malayi Cytochrome P450 family protein 0.001 0.0005 0.0004
Echinococcus granulosus Tubulin beta 2C chain 0.0123 0.0287 0.0939
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0006
Brugia malayi serpin 0.0012 0.0008 0.0009
Schistosoma mansoni hypothetical protein 0.0095 0.0217 0.1191
Loa Loa (eye worm) hypothetical protein 0.0169 0.0403 0.059
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0253 0.0615 0.0898
Schistosoma mansoni protein phosphatase 2C 0.001 0.0003 0.0002
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0048 0.0099 0.0546
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0015 0.0015 0.0072
Brugia malayi beta-lactamase 0.0037 0.0071 0.01
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.001 0.0005 0.002
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0011 0.0007 0.0029
Echinococcus granulosus tumor protein p63 0.0256 0.0622 0.2036
Loa Loa (eye worm) integrin beta-2 0.0233 0.0564 0.0825
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0005 0.0025
Schistosoma mansoni biogenic amine receptor 0.0253 0.0615 0.3395
Leishmania major farnesyltransferase beta subunit 0.0111 0.0257 0.1417
Leishmania major hypothetical protein, conserved 0.001 0.0005 0.0018
Brugia malayi serpin (BmSERPIN) 0.0012 0.0008 0.0009
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0253 0.0615 0.0901
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0009 0.0046
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0089 0.0202 0.1095
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0096 0.0314
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0096 0.022 0.1206
Echinococcus multilocularis g-protein coupled receptor 0.0253 0.0615 0.2012
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0071 0.3225
Brugia malayi nuclear receptor NHR-88 0.001 0.0005 0.0003
Brugia malayi hypothetical protein 0.0253 0.0615 0.0898
Brugia malayi serpin (BmSERPIN) 0.0012 0.0008 0.0009
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Loa Loa (eye worm) hypothetical protein 0.0037 0.0071 0.0104
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0111 0.0257 0.1411
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.001 0.0005 0.002
Entamoeba histolytica ATP-binding cassette protein, putative 0.0011 0.0007 0.0013
Echinococcus multilocularis voltage dependent calcium channel 0.001 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0095 0.0217 0.0318
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.0012
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.001 0.0003 0.0015
Leishmania major DNA polymerase eta, putative 0.0038 0.0075 0.0407
Loa Loa (eye worm) tubulin beta-1 chain 0.0123 0.0287 0.042
Onchocerca volvulus 0.0012 0.0008 0.0013
Trypanosoma brucei prolyl endopeptidase 0.0023 0.0036 0.0192
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0006
Brugia malayi STAT protein, DNA binding domain containing protein 0.0047 0.0096 0.0138
Brugia malayi Cation transporter family protein 0.0015 0.0017 0.0021
Trichomonas vaginalis tubulin epsilon chain, putative 0.0123 0.0287 0.1577
Brugia malayi G protein-coupled receptor F59B2.13 0.0253 0.0615 0.0898
Loa Loa (eye worm) beta-lactamase 0.0037 0.0071 0.0104
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0096 0.0518
Schistosoma mansoni ATP-binding cassette transporter 0.0034 0.0065 0.0347
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0253 0.0615 0.2012
Brugia malayi Bromodomain containing protein 0.0033 0.0062 0.0087
Giardia lamblia DNA damage repair protein 0.0012 0.0009 0.0017
Schistosoma mansoni serine protease inhibitors serpins 0.0012 0.0008 0.0034
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0009 0.0373
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Echinococcus multilocularis dro:myosuppressin receptor 0.0253 0.0615 0.2012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Loa Loa (eye worm) DEAH box polypeptide 35 0.0022 0.0033 0.0048
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.005 0.0105 0.0578
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0727 0.1807 1
Schistosoma mansoni caspase-7 (C14 family) 0.0015 0.0015 0.0072
Loa Loa (eye worm) BEN-1 protein 0.0123 0.0287 0.042
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0105 0.0578
Brugia malayi RNase H family protein 0.0011 0.0007 0.0007
Brugia malayi beta-lactamase family protein 0.0037 0.0071 0.01
Giardia lamblia Rab geranylgeranyltransferase 0.0037 0.0071 0.036
Leishmania major DNA polymerase eta, putative 0.0065 0.0143 0.0785
Loa Loa (eye worm) hypothetical protein 0.0355 0.087 0.1275
Brugia malayi nuclear hormone receptor 0.001 0.0005 0.0003
Echinococcus granulosus Tubulin beta 2C chain 0.0123 0.0287 0.0939
Echinococcus granulosus Tubulin beta 2C chain 0.0123 0.0287 0.0939
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0005 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0044 0.009 0.0478
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Echinococcus granulosus prolyl endopeptidase 0.0023 0.0036 0.0116
Trypanosoma cruzi extracellular receptor, putative 0.001 0.0004 0.0023
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0111 0.0257 0.0376
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0012
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.001 0.0003 0.0001
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0123 0.0287 0.0939
Leishmania major metacaspase, putative 0.0015 0.0015 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0078 0.0424
Brugia malayi CXXC zinc finger family protein 0.0012 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0727 0.1807 0.591
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0078 0.0254
Echinococcus multilocularis neuropeptide receptor A26 0.0253 0.0615 0.2012
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0056 0.012 0.0656
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0071 0.0388
Leishmania major lanosterol synthase, putative 0.0057 0.0121 0.0662
Leishmania major DNA polymerase kappa, putative 0.0039 0.0078 0.0423
Schistosoma mansoni neuropeptide F-like receptor 0.0253 0.0615 0.3395
Brugia malayi hypothetical protein 0.0253 0.0615 0.0898
Brugia malayi hypothetical protein 0.0253 0.0615 0.0898
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0012 0.0009 0.0046
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0111 0.0257 0.1411
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0005 0.0003
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0071 0.0386
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.001 0.0005 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0044 0.009 0.0129
Entamoeba histolytica serine protease inhibitor, putative 0.0012 0.0008 0.0024
Trypanosoma brucei p-glycoprotein 0.0011 0.0007 0.0031
Toxoplasma gondii leucyl aminopeptidase LAP 0.0056 0.012 0.0117
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0011 0.0007 0.0036
Schistosoma mansoni tsg101-related 0.0082 0.0185 0.1011
Entamoeba histolytica hypothetical protein 0.0037 0.0071 0.037
Mycobacterium ulcerans short chain dehydrogenase 0.0011 0.0007 0.0254
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0053 0.0175
Onchocerca volvulus 0.0037 0.0071 0.0204
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0727 0.1807 0.1805
Trypanosoma cruzi cysteine proteinase, putative 0.0023 0.0036 0.02
Echinococcus granulosus somatostatin receptor 0.0253 0.0615 0.2012
Schistosoma mansoni P2X receptor subunit 0.0099 0.0227 0.1244
Trypanosoma cruzi metacaspase 5, putative 0.0015 0.0015 0.0085
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0079 0.0438
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0078 0.0417
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0111 0.0257 0.1411
Leishmania major cathepsin L-like protease 0.0044 0.009 0.0494
Loa Loa (eye worm) transcription factor SMAD2 0.0089 0.0201 0.0294
Loa Loa (eye worm) fibroinase 0.0044 0.009 0.0132
Entamoeba histolytica ATP-binding cassette protein, putative 0.0011 0.0007 0.0013
Brugia malayi hypothetical protein 0.0253 0.0615 0.0898
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0089 0.0202 0.0659
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0109 0.0592
Schistosoma mansoni hypothetical protein 0.0253 0.0615 0.3395
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Loa Loa (eye worm) hypothetical protein 0.0095 0.0217 0.0318
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.002 0.0028 0.0093
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0005 0.0015
Giardia lamblia Prenyltransferase 0.0111 0.0257 0.1393
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Brugia malayi hypothetical protein 0.0035 0.0067 0.0095
Echinococcus granulosus integrin alpha 3 0.0069 0.0152 0.0497
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0037 0.0071 0.0068
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0111 0.0257 0.141
Loa Loa (eye worm) hypothetical protein 0.0727 0.1807 0.2647
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0727 0.1807 0.5507
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0253 0.0615 0.3395
Onchocerca volvulus 0.0037 0.0073 0.021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0015 0.0015 0.0072
Echinococcus granulosus cathepsin L cysteine protease 0.0023 0.0036 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Chlamydia trachomatis DNA topoisomerase I 0.0029 0.0052 0.1421
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0095 0.0217 0.0711
Echinococcus granulosus biogenic amine 5HT receptor 0.0253 0.0615 0.2012
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0032 0.0058 0.032
Echinococcus multilocularis g protein coupled receptor 0.0253 0.0615 0.2012
Trypanosoma cruzi multidrug resistance protein E, putative 0.0011 0.0007 0.0036
Echinococcus multilocularis atrial natriuretic peptide receptor 0.001 0.0004 0.0014
Brugia malayi hypothetical protein 0.0298 0.0729 0.1065
Onchocerca volvulus 0.0253 0.0615 0.1866
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0053 0.0051
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0727 0.1807 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0253 0.0615 0.2012
Trypanosoma brucei cytochrome P450, putative 0.001 0.0005 0.0022
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0102 0.0146
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0089 0.0202 0.1104
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.001 0.0004 0.0006
Echinococcus granulosus serotonin receptor 0.0253 0.0615 0.2012
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.001 0.0049
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0071 0.0379
Echinococcus multilocularis multidrug resistance associated protein 1 0.0011 0.0007 0.0021
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Brugia malayi Trypsin family protein 0.04 0.0984 0.1438
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0027
Onchocerca volvulus 0.0253 0.0615 0.1866
Echinococcus granulosus beta tubulin 0.0123 0.0287 0.0939
Onchocerca volvulus 0.0095 0.0217 0.0651
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0009 0.0001 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Trypanosoma cruzi metacaspase, putative 0.0015 0.0015 0.0085
Onchocerca volvulus Cathepsin F homolog 0.0044 0.009 0.0264
Echinococcus multilocularis serotonin receptor 0.0253 0.0615 0.2012
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0015 0.0015 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0022
Leishmania major cathepsin L-like protease 0.0044 0.009 0.0494
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0037 0.0071 0.0389
Echinococcus granulosus alpha 1A adrenergic receptor 0.0253 0.0615 0.2012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488
Onchocerca volvulus 0.0044 0.009 0.0264
Echinococcus multilocularis Mastin 0.0095 0.0217 0.0711
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0044 0.0231
Echinococcus granulosus neuropeptides capa receptor 0.0253 0.0615 0.2012
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0071 0.0232
Echinococcus granulosus transmembrane protease serine 3 0.0095 0.0217 0.0711
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0037 0.0071 0.0372
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0023 0.0036 0.0049
Schistosoma mansoni tubulin subunit beta 0.0123 0.0287 0.1577
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0011 0.0006 0.0032
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0224 0.0731
Echinococcus multilocularis tubulin subunit beta 0.0123 0.0287 0.0939
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0011 0.0006 0.0025
Loa Loa (eye worm) calcium channel 0.001 0.0003 0.0004
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0029 0.0052 0.0075
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0015 0.007
Plasmodium falciparum metacaspase-like protein 0.0015 0.0015 0.007
Brugia malayi Cathepsin L-like precursor 0.0044 0.009 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Echinococcus granulosus metabotropic glutamate receptor 2 0.001 0.0004 0.0014
Schistosoma mansoni hypothetical protein 0.0253 0.0615 0.3395
Schistosoma mansoni hypothetical protein 0.0043 0.0086 0.0462
Loa Loa (eye worm) hypothetical protein 0.0037 0.0071 0.0104
Echinococcus granulosus biogenic amine 5HT receptor 0.0253 0.0615 0.2012
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0253 0.0615 0.2012
Leishmania major hypothetical protein, conserved 0.001 0.0005 0.0018
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0033 0.0062 0.0338
Plasmodium falciparum geranylgeranyltransferase, putative 0.0037 0.0071 0.0379
Loa Loa (eye worm) hypothetical protein 0.0078 0.0175 0.0257
Loa Loa (eye worm) hypothetical protein 0.0298 0.0729 0.1068
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0095 0.0217 0.0711
Echinococcus granulosus sodium:myo inositol cotransporter 0.0039 0.0077 0.0252
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Echinococcus granulosus Mastin 0.0095 0.0217 0.0711
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0013
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0023 0.0036 0.0052
Brugia malayi Cathepsin L-like precursor 0.0044 0.009 0.0129
Echinococcus granulosus plasminogen activator inhibitor 2 0.0012 0.0008 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0136 0.075
Loa Loa (eye worm) hypothetical protein 0.0096 0.022 0.0322
Giardia lamblia DINP protein human, muc B family 0.0039 0.0078 0.0396
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0005 0.0003
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0253 0.0615 0.2012
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0078 0.0424
Echinococcus multilocularis neuropeptide Y receptor 0.0253 0.0615 0.2012
Schistosoma mansoni tubulin subunit beta 0.0123 0.0287 0.1577
Loa Loa (eye worm) hypothetical protein 0.0051 0.0107 0.0156
Schistosoma mansoni P2X receptor subunit 0.0099 0.0227 0.1244
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0121
Echinococcus multilocularis lysine specific demethylase 6a 0.001 0.0003 0.0009
Schistosoma mansoni glutamate receptor AMPA 0.0034 0.0065 0.0345
Schistosoma mansoni sodium/solute symporter 0.0039 0.0077 0.0413
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.002 0.0028 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.009 0.0488
Echinococcus multilocularis serotonin receptor 0.0253 0.0615 0.2012
Echinococcus multilocularis glutamate receptor subunit protein glur 0.002 0.0028 0.0093
Loa Loa (eye worm) cysteine protease 0.0044 0.009 0.0132
Echinococcus granulosus cathepsin l cysteine peptidase 0.0044 0.009 0.0296
Schistosoma mansoni metabotropic glutamate receptor 0.001 0.0004 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0136 0.0746
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0009 0.0046
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0109 0.0358
Schistosoma mansoni nuclear hormone receptor 0.001 0.0005 0.0012
Brugia malayi hypothetical protein 0.001 0.0004 0.0003
Echinococcus granulosus glutamate NMDA receptor subunit 0.008 0.0179 0.0586
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0025 0.0041 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0015 0.0072
Toxoplasma gondii histone lysine methyltransferase SET1 0.0027 0.0046 0.0043
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0009 0.0046
Echinococcus granulosus integrin alpha ps 0.0069 0.0152 0.0497
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0044 0.009 0.0295
Schistosoma mansoni hypothetical protein 0.0029 0.0052 0.0273
Schistosoma mansoni hypothetical protein 0.0095 0.0217 0.1191
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0078
Trypanosoma brucei ingi protein (ORF1) 0.0012 0.001 0.0049
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0028 0.0049 0.0257
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0044 0.009 0.0296
Entamoeba histolytica cysteine proteinase 2 0.0023 0.0036 0.0178
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0009 0.0001 0.0007
Leishmania major extracellular receptor, putative 0.001 0.0004 0.0016
Loa Loa (eye worm) MH2 domain-containing protein 0.0089 0.0201 0.0294
Echinococcus multilocularis jumonji domain containing 1A 0.001 0.0003 0.0009
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.001 0.0005 0.0015
Trichomonas vaginalis tubulin, putative 0.0123 0.0287 0.1577
Brugia malayi Tubulin beta-1 chain 0.0123 0.0287 0.0417
Loa Loa (eye worm) hypothetical protein 0.0037 0.0071 0.0104
Plasmodium vivax unspecified product 0.0023 0.0036 0.0186
Onchocerca volvulus 0.0095 0.0217 0.0651
Schistosoma mansoni serine protease inhibitors serpins 0.0012 0.0008 0.0034
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0029 0.0052 0.0271
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0012 0.0009 0.003
Chlamydia trachomatis SWIB complex protein 0.0029 0.0052 0.1421
Brugia malayi Cathepsin L-like precursor 0.0044 0.009 0.0129
Echinococcus multilocularis Tubulin beta 2C chain 0.0123 0.0287 0.0939
Loa Loa (eye worm) hypothetical protein 0.003 0.0055 0.008
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0535 0.1322 0.4326
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0053 0.0051
Echinococcus granulosus orexin receptor type 2 0.0253 0.0615 0.2012
Echinococcus multilocularis geminin 0.0198 0.0477 0.156
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0253 0.0615 0.2012
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.0011 0.0006 0.0017
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0037 0.0071 0.0394
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0005 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0109 0.0592
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.001 0.0005 0.0025
Schistosoma mansoni cercarial elastase (S01 family) 0.0095 0.0217 0.1191
Leishmania major cathepsin L-like protease 0.0044 0.009 0.0494
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0005 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0078 0.0424
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0011 0.0007 0.0037
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0078 0.0424
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Schistosoma mansoni thyroid hormone receptor 0.001 0.0005 0.0012
Toxoplasma gondii hypothetical protein 0.0071 0.0158 0.0155
Loa Loa (eye worm) TK/ROR protein kinase 0.0072 0.0159 0.0233
Leishmania major beta tubulin 0.0123 0.0287 0.1583
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0085 0.0122
Brugia malayi MAP kinase sur-1 0.0052 0.0109 0.0157
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0089 0.0202 0.0295
Brugia malayi prolyl oligopeptidase family protein 0.0023 0.0036 0.0049
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0044 0.009 0.0295
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0074 0.0374
Brugia malayi RNase H family protein 0.0011 0.0007 0.0007
Treponema pallidum ATP-dependent RNA helicase 0.0727 0.1807 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0109 0.0605
Echinococcus granulosus 7TM GPCR rhodopsin 0.0253 0.0615 0.2012
Leishmania major DNA damage repair protein, putative 0.0012 0.0009 0.0045
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0085 0.0125
Echinococcus granulosus jumonji domain containing 1A 0.001 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Loa Loa (eye worm) serpin protein 6 0.0012 0.0008 0.0012
Brugia malayi jmjC domain containing protein 0.0097 0.0224 0.0324
Trypanosoma brucei beta tubulin 0.0123 0.0287 0.1584
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.005 0.0105 0.0578
Onchocerca volvulus 0.0041 0.0083 0.0239
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0253 0.0615 0.2012
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0331 0.1823
Echinococcus multilocularis zinc finger protein Ran binding 0.001 0.0005 0.0015
Trypanosoma cruzi metacaspase 5, putative 0.0015 0.0015 0.0085
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0009 0.0052
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0109 0.06
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0071 0.038
Leishmania major eukaryotic initiation factor 4a, putative 0.0727 0.1807 1
Brugia malayi Glutamate receptor 2 precursor 0.0034 0.0065 0.0091
Plasmodium vivax hypothetical protein, conserved 0.001 0.0005 0.0012
Brugia malayi Angiotensin-converting enzyme family protein 0.1375 0.3436 0.5032
Plasmodium vivax vivapain-1 0.0023 0.0036 0.0186
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0009 0.0373
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0012
Brugia malayi Serpin protein 6 0.0012 0.0008 0.0009
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0039 0.0077 0.0252
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0022 0.0124
Toxoplasma gondii ran binding protein 0.001 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0024
Brugia malayi steroid hormone receptor 0.001 0.0005 0.0003
Trypanosoma cruzi prolyl endopeptidase 0.0023 0.0036 0.0197
Schistosoma mansoni DNA polymerase eta 0.0065 0.0143 0.0779
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0082 0.0269
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0122 0.0285 0.0417
Mycobacterium ulcerans hypothetical protein 0.0037 0.0071 0.3225
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0012 0.0053
Loa Loa (eye worm) hypothetical protein 0.0054 0.0113 0.0165
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0111 0.0257 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0109 0.0592
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0253 0.0615 0.3395
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0078 0.0417
Echinococcus granulosus tyrosine kinase 0.001 0.0004 0.0014
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0109 0.016
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.005 0.0105 0.0151
Echinococcus multilocularis Estrogen regulated protein EP45 0.0012 0.0008 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0253 0.0615 0.2012
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0037 0.0071 0.0233
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0122 0.0285 0.1565
Echinococcus multilocularis serine protease inhibitor 0.0012 0.0008 0.0028
Schistosoma mansoni neuropeptide f receptor 76f 0.0253 0.0615 0.3395
Brugia malayi Calcitonin receptor-like protein seb-1 0.0078 0.0175 0.0254
Trypanosoma cruzi cysteine peptidase, putative 0.0015 0.0016 0.0086
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0044 0.009 0.0295
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0005 0.0006
Echinococcus multilocularis transcription elongation factor b polypeptide 1 0.0043 0.0086 0.0281
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0217 0.1191
Mycobacterium tuberculosis Conserved protein 0.0037 0.0071 0.0386
Leishmania major cathepsin L-like protease 0.0062 0.0136 0.0744
Trichomonas vaginalis esterase, putative 0.0037 0.0071 0.038
Schistosoma mansoni cathepsin F (C01 family) 0.0044 0.009 0.0488
Loa Loa (eye worm) hypothetical protein 0.0065 0.0143 0.0209
Loa Loa (eye worm) hypothetical protein 0.0253 0.0615 0.0901
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0053 0.0283
Brugia malayi Cathepsin L-like precursor 0.0044 0.009 0.0129
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0006
Brugia malayi Cathepsin L-like precursor 0.003 0.0053 0.0075
Echinococcus multilocularis neuropeptide FF receptor 2 0.0253 0.0615 0.2012
Onchocerca volvulus 0.001 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0012
Mycobacterium ulcerans lipase LipD 0.0037 0.0071 0.3225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.009 0.0488

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 32.6427 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 141.2538 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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