Detailed information for compound 1380015

Basic information

Technical information
  • TDR Targets ID: 1380015
  • Name: [2-[(2-chloropyridin-3-yl)amino]-2-oxoethyl] 4-amino-5-chloro-2-methoxybenzoate
  • MW: 370.187 | Formula: C15H13Cl2N3O4
  • H donors: 2 H acceptors: 3 LogP: 2.49 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(N)c(cc1C(=O)OCC(=O)Nc1cccnc1Cl)Cl
  • InChi: 1S/C15H13Cl2N3O4/c1-23-12-6-10(18)9(16)5-8(12)15(22)24-7-13(21)20-11-3-2-4-19-14(11)17/h2-6H,7,18H2,1H3,(H,20,21)
  • InChiKey: OAJHNSXIIQVKRU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [2-[(2-chloro-3-pyridyl)amino]-2-oxo-ethyl] 4-amino-5-chloro-2-methoxy-benzoate
  • 4-amino-5-chloro-2-methoxybenzoic acid [2-[(2-chloro-3-pyridyl)amino]-2-oxoethyl] ester
  • 4-amino-5-chloro-2-methoxy-benzoic acid [2-[(2-chloro-3-pyridyl)amino]-2-keto-ethyl] ester
  • [2-[(2-chloropyridin-3-yl)amino]-2-oxo-ethyl] 4-amino-5-chloro-2-methoxy-benzoate
  • ZINC07656657

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens K(lysine) acetyltransferase 2A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis bromodomain-containing protein, putative Get druggable targets OG5_127781 All targets in OG5_127781
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium vivax histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica acetyltransferase, GNAT family Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum hypothetical protein Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum Bromodomain containing protein, related Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-B Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium hominis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium yoelii histone acetyltransferase GCN5-related Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma japonicum ko:K06062 p300/CBP-associated factor, putative Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium parvum GCN5 like acetylase + bromodomain Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium falciparum histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Babesia bovis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium knowlesi histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-A Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium berghei histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Theileria parva histone acetyltransferase Gcn5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Giardia lamblia Histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 Get druggable targets OG5_127781 All targets in OG5_127781
Brugia malayi acetyltransferase, GNAT family protein Get druggable targets OG5_127781 All targets in OG5_127781
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0079 0.0172
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0054 0.0114 0.0255
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.002 0.0124
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0163 0.0475 0.0475
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0086 0.022 0.022
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0074 0.018 0.018
Mycobacterium tuberculosis Probable oxidoreductase 0.0123 0.0341 0.0653
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0064 0.0146 0.0752
Trypanosoma brucei DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Echinococcus granulosus cpg binding protein 0.0106 0.0284 0.0284
Echinococcus multilocularis centrosomal protein of 41 kDa 0.0028 0.0028 0.0028
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0052 0.0108 0.0108
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.0144 0.1253
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.002 0.0046
Loa Loa (eye worm) hypothetical protein 0.0469 0.1483 0.7951
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0052 0.0109
Brugia malayi Inositol-1 0.0043 0.0079 0.0389
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0048 0.0095 0.0095
Trypanosoma brucei DNA polymerase IV, putative 0.0151 0.0434 0.3884
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0071 0.0071
Schistosoma mansoni sex comb on midleg homolog 0.0056 0.0121 0.0119
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0054 0.0114 0.0972
Echinococcus granulosus Rhodanese 0.0028 0.0028 0.0028
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0026 0.002 0.0028
Schistosoma mansoni microtubule-associated protein tau 0.305 1 1
Schistosoma mansoni tyrosine kinase 0.0048 0.0095 0.0093
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0118 0.0602
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1292 0.4198 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0191 0.0567 0.0567
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0049 0.0097 0.082
Echinococcus granulosus ecdysone induced protein 78C 0.0055 0.0118 0.0118
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0083 0.0425
Schistosoma mansoni DNA helicase recq5 0.0074 0.018 0.0178
Loa Loa (eye worm) hypothetical protein 0.0469 0.1483 0.7951
Schistosoma mansoni hypothetical protein 0.0123 0.0342 0.0341
Trichomonas vaginalis DNA helicase recq, putative 0.0116 0.0319 0.0746
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0099 0.0262 0.0609
Plasmodium vivax hexokinase, putative 0.0081 0.0202 0.3922
Brugia malayi succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial 0.0059 0.013 0.0665
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0055 0.0118 0.0118
Schistosoma mansoni aldehyde dehydrogenase 0.0136 0.0383 0.0381
Echinococcus multilocularis lysosomal alpha glucosidase 0.0191 0.0567 0.0567
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.029 0.258
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0055 0.0118 0.0118
Brugia malayi Protein kinase domain containing protein 0.0163 0.0475 0.252
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0304 0.058
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0028 0.0028 0.005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0049 0.0097 0.0215
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.002 0.0225
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0041 0.0069 0.0069
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0076 0.0165
Brugia malayi jmjC domain containing protein 0.0175 0.0513 0.2726
Echinococcus granulosus Niemann Pick C1 protein 0.0165 0.0481 0.0481
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0202 0.1778
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.002 0.0124
Brugia malayi Rhodanese-like domain containing protein 0.0028 0.0028 0.0114
Schistosoma mansoni hypothetical protein 0.0041 0.0071 0.0069
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0039 0.0064 0.0086
Loa Loa (eye worm) hypothetical protein 0.006 0.0134 0.0702
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0024 0.0157
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0118 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Loa Loa (eye worm) acetyltransferase 0.0329 0.102 0.5463
Echinococcus multilocularis ubiquitin specific protease 41 0.0049 0.0097 0.0097
Echinococcus multilocularis polycomb protein SCMH1 0.0056 0.0121 0.0121
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0108 0.029 0.0554
Plasmodium falciparum LCCL domain-containing protein 0.0106 0.0287 0.5623
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0007 0.0007
Mycobacterium ulcerans DNA polymerase IV 0.0172 0.0505 0.0938
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0074 0.018 0.0932
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0163 0.0475 0.2532
Plasmodium vivax thioredoxin reductase, putative 0.0055 0.0116 0.2198
Echinococcus granulosus centrosomal protein of 41 kDa 0.0028 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0112 0.0305 0.1619
Plasmodium vivax flavoprotein subunit of succinate dehydrogenase, putative 0.0025 0.0018 0.0228
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.002 0.0119
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0029 0.0032 0.0032
Brugia malayi RNA, U transporter 1 0.0083 0.021 0.1094
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0049 0.0097 0.082
Trypanosoma brucei DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Brugia malayi hypothetical protein 0.0029 0.0032 0.0138
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0033 0.0033
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0041 0.0069 0.0571
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0631 0.2018 0.3912
Schistosoma mansoni tyrosine kinase 0.008 0.0201 0.0199
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0312 0.0965 0.5166
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0099 0.0262 0.0609
Mycobacterium tuberculosis Probable fumarate reductase [flavoprotein subunit] FrdA (fumarate dehydrogenase) (fumaric hydrogenase) 0.0025 0.0018 0.0024
Brugia malayi nuclear receptor RXR 0.0026 0.0022 0.0082
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0045 0.0083 0.0692
Schistosoma mansoni jumonji/arid domain-containing protein 0.0175 0.0513 0.0511
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0049 0.0097 0.0486
Trichomonas vaginalis rotamase, putative 0.0035 0.0052 0.0109
Entamoeba histolytica rodhanase-like domain containing protein 0.0138 0.039 0.0914
Brugia malayi Rhodanese-like domain containing protein 0.0138 0.039 0.2063
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0079 0.0172
Treponema pallidum fructose-bisphosphate aldolase 0.1292 0.4198 1
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0028 0.0028 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0007 0.0006
Echinococcus multilocularis microtubule associated protein 2 0.305 1 1
Trichomonas vaginalis thiosulfate sulfertansferase, putative 0.0028 0.0028 0.005
Plasmodium falciparum thioredoxin reductase 0.0026 0.002 0.0273
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0074 0.0161
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.0022 0.0097
Schistosoma mansoni phd/f-box containing protein 0.0045 0.0083 0.0081
Brugia malayi hexokinase type II 0.0026 0.002 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0258 0.06
Schistosoma mansoni phosphoglycerate kinase 0.0172 0.0505 0.0503
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0048 0.0095 0.1773
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0007 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0315 0.0737
Brugia malayi Cell death protein 3 precursor 0.0222 0.0668 0.3563
Onchocerca volvulus 0.0081 0.0202 0.1256
Brugia malayi Rhodanese-like domain containing protein 0.0138 0.039 0.2063
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.002 0.002
Echinococcus granulosus thioredoxin glutathione reductase 0.0055 0.0118 0.0118
Schistosoma mansoni tyrosine kinase 0.0081 0.0203 0.0202
Toxoplasma gondii TIM10 family protein, putative 0.0048 0.0095 0.1514
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0158 0.138
Chlamydia trachomatis hypothetical protein 0.0028 0.0028 0.02
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0008 0.0003
Echinococcus multilocularis transcription factor eb 0.0109 0.0296 0.0296
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0166 0.1451
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0163 0.0475 0.252
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0108 0.029 0.5699
Loa Loa (eye worm) hypothetical protein 0.0064 0.0146 0.0766
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0052 0.0246
Brugia malayi TAZ zinc finger family protein 0.013 0.0364 0.1924
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.0022 0.0022
Brugia malayi Thiosulfate sulfurtransferase D2023.5 0.0028 0.0028 0.0114
Onchocerca volvulus 0.0153 0.044 0.2879
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0229 0.0693 0.0693
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0055 0.0118 0.0602
Loa Loa (eye worm) hypothetical protein 0.0045 0.0084 0.0434
Schistosoma mansoni alpha-glucosidase 0.0165 0.0479 0.0478
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0054 0.0114 0.0255
Trichomonas vaginalis cdc25b, putative 0.0138 0.039 0.0914
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0108 0.029 0.258
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0086 0.022 0.0218
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.0022 0.002
Leishmania major metacaspase, putative 0.0099 0.0262 0.2318
Onchocerca volvulus 0.0026 0.0022 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Trypanosoma cruzi metacaspase, putative 0.0099 0.0262 0.2318
Trypanosoma cruzi DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Echinococcus granulosus 5'partial|tRNA 2 selenouridine synthase 0.0028 0.0028 0.0028
Brugia malayi Muscleblind-like protein 0.0151 0.0434 0.2301
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0054 0.0114 0.2148
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0074 0.018 0.018
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0258 0.06
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0041 0.0069 0.0571
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0079 0.0172
Giardia lamblia Dual specificity phosphatase Cdc25, putative 0.0028 0.0028 0.005
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0315 0.0737
Onchocerca volvulus 0.0123 0.0342 0.2214
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0024 0.0157
Brugia malayi glutathione reductase 0.0055 0.0116 0.0589
Leishmania major eukaryotic translation initiation factor-like protein 0.0041 0.0069 0.0571
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Trypanosoma cruzi metacaspase 5, putative 0.0099 0.0262 0.2318
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0086
Echinococcus multilocularis muscleblind protein 1 0.0151 0.0434 0.0434
Schistosoma mansoni protein phosphatase 2C 0.0045 0.0083 0.0081
Plasmodium falciparum JmjC domain-containing protein, putative 0.0045 0.0083 0.1528
Echinococcus multilocularis expressed protein 0.0048 0.0095 0.0095
Echinococcus multilocularis caspase 0.0261 0.0798 0.0798
Trichomonas vaginalis glutaminase, putative 0.0277 0.085 0.2011
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0132 0.0372 0.1967
Giardia lamblia DINP protein human, muc B family 0.0108 0.029 0.0677
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0089 0.0229 0.2025
Echinococcus granulosus hexokinase 0.0081 0.0202 0.0202
Trichomonas vaginalis STE family protein kinase 0.0089 0.0229 0.0532
Leishmania major trypanothione reductase 0.0055 0.0116 0.0995
Loa Loa (eye worm) hexokinase 0.0025 0.0018 0.0077
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0132 0.0372 0.037
Mycobacterium tuberculosis Possible transcriptional regulatory protein (possibly ArsR-family) 0.0028 0.0028 0.0043
Plasmodium vivax histone acetyltransferase GCN5, putative 0.01 0.0266 0.5206
Trypanosoma brucei metacaspase 0.0099 0.0262 0.2318
Schistosoma mansoni dual specificity protein phosphatase 0.0036 0.0054 0.0052
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0076 0.0165
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0036 0.0055 0.0979
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0202 0.1778
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0005
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0071 0.0071
Echinococcus multilocularis expressed protein 0.0035 0.0052 0.0052
Loa Loa (eye worm) glutathione reductase 0.0055 0.0116 0.0604
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0202 0.1778
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0049 0.0097 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0262 0.0609
Mycobacterium ulcerans molybdopterin biosynthesis-like protein MoeZ 0.0028 0.0028 0.0042
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0028 0.0028 0.005
Brugia malayi jmjC domain containing protein 0.0045 0.0083 0.041
Brugia malayi nuclear hormone receptor 0.0055 0.0118 0.0602
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0074 0.018 0.018
Echinococcus multilocularis Protein lozenge 0.0059 0.013 0.013
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0045 0.0083 0.0081
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.0059 0.013 0.0128
Trypanosoma brucei glucosidase, putative 0.0042 0.0076 0.0629
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0158 0.138
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0076 0.0165
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Echinococcus granulosus Protein patched homolog 1 0.005 0.0099 0.0099
Trypanosoma brucei hexokinase 0.0081 0.0202 0.1775
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0055 0.0118 0.0616
Plasmodium falciparum hexokinase 0.0081 0.0202 0.3922
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0055 0.0118 0.0118
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0033 0.0031
Onchocerca volvulus 0.0028 0.0028 0.0066
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0049 0.0097 0.082
Echinococcus multilocularis Niemann Pick C1 protein 0.0116 0.0317 0.0317
Leishmania major DNA damage repair protein, putative 0.0027 0.0024 0.0157
Schistosoma mansoni myelin transcription factor 1 myt1 0.0064 0.0146 0.0144
Brugia malayi ecdysone receptor 0.0026 0.0022 0.0082
Brugia malayi hypothetical protein 0.0026 0.0022 0.0082
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0007 0.0016
Trypanosoma brucei DNA polymerase IV, putative 0.0172 0.0505 0.4526
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0169 0.0386
Trichomonas vaginalis DNA helicase recq1, putative 0.0116 0.0319 0.0746
Entamoeba histolytica deoxycytidyl transferase, putative 0.0086 0.022 0.0509
Schistosoma mansoni hypothetical protein 0.0048 0.0094 0.0092
Echinococcus multilocularis lipoxygenase domain containing protein 0.0106 0.0287 0.0287
Mycobacterium ulcerans aldehyde dehydrogenase 0.0136 0.0383 0.071
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0038 0.006 0.0489
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0079 0.1251
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0028 0.0192
Schistosoma mansoni glutaminase 0.0277 0.085 0.0848
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0076 0.0165
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0079 0.0657
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0002 0.0002
Schistosoma mansoni jumonji domain containing protein 0.0045 0.0083 0.0081
Mycobacterium tuberculosis Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) 0.0025 0.0018 0.0024
Loa Loa (eye worm) hypothetical protein 0.0222 0.0668 0.3573
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0109 0.0294 0.156
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0584 0.1864 0.1864
Schistosoma mansoni phosphoglycerate kinase 0.0172 0.0505 0.0503
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0166 0.1451
Trypanosoma brucei DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0496 0.1573 0.1573
Loa Loa (eye worm) thiosulfate sulfurtransferase 0.0028 0.0028 0.0129
Trypanosoma cruzi As/Sb Reductase, putative 0.0028 0.0028 0.0192
Echinococcus granulosus epidermal growth factor receptor 0.0151 0.0434 0.0434
Loa Loa (eye worm) CBP-B 0.0093 0.0244 0.1291
Echinococcus granulosus caspase 3 0.0162 0.0472 0.0472
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0138 0.039 0.0914
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0261 0.0798 0.0798
Brugia malayi PHD-finger family protein 0.003 0.0033 0.0143
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0074 0.0161
Entamoeba histolytica hypothetical protein 0.0028 0.0028 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0055 0.0118 0.0616
Echinococcus multilocularis epidermal growth factor receptor 0.0151 0.0434 0.0434
Trypanosoma cruzi DNA damage repair protein, putative 0.0027 0.0024 0.0157
Brugia malayi hypothetical protein 0.0153 0.044 0.2332
Brugia malayi RIKEN cDNA 4930451A13 0.0028 0.0028 0.0114
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0099 0.0262 0.0609
Echinococcus granulosus jumonji domain containing 1A 0.0045 0.0083 0.0083
Trypanosoma cruzi hexokinase, putative 0.0081 0.0202 0.1775
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0258 0.06
Echinococcus multilocularis neuropeptide receptor A26 0.0544 0.1729 0.1729
Schistosoma mansoni caspase-7 (C14 family) 0.0222 0.0668 0.0667
Trypanosoma cruzi hexokinase, putative 0.0081 0.0202 0.1775
Entamoeba histolytica hypothetical protein 0.0028 0.0028 0.005
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.006 0.0486
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0137 0.0716
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0038 0.006 0.0917
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0118 0.0602
Brugia malayi hypothetical protein 0.0106 0.0287 0.1508
Giardia lamblia Phosphoglycerate kinase 0.0172 0.0505 0.1188
Brugia malayi hypothetical protein 0.0029 0.0032 0.0138
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0315 0.2808
Loa Loa (eye worm) histone methyltransferase 0.003 0.0036 0.0171
Trypanosoma cruzi succinate dehydrogenase, putative 0.0038 0.006 0.0489
Echinococcus granulosus hypothetical protein 0.0032 0.0041 0.0041
Onchocerca volvulus 0.0081 0.0202 0.1256
Echinococcus granulosus apoptotic protease activating factor 1 0.0123 0.0342 0.0342
Brugia malayi PHD-finger family protein 0.0045 0.0084 0.0415
Leishmania major 3-mercaptopyruvate sulfurtransferase 0.0028 0.0028 0.0192
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0425
Brugia malayi Protein kinase domain containing protein 0.0048 0.0095 0.0476
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0028
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0029 0.0032 0.0153
Plasmodium falciparum flap endonuclease 1 0.0026 0.0023 0.0324
Entamoeba histolytica hypothetical protein 0.0028 0.0028 0.005
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0074 0.0074
Trypanosoma cruzi metacaspase 5, putative 0.0099 0.0262 0.2318
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0033 0.0455
Echinococcus granulosus polycomb protein SCMH1 0.0056 0.0121 0.0121
Schistosoma mansoni hypothetical protein 0.0048 0.0094 0.0092
Schistosoma mansoni tyrosine kinase 0.008 0.0201 0.0199
Trypanosoma cruzi Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0025 0.0018 0.0103
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0032 0.0231
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0616
Schistosoma mansoni chromobox protein 0.0071 0.0169 0.0167
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0032 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0083 0.0425
Echinococcus multilocularis 0.0047 0.009 0.009
Leishmania major hypothetical protein, conserved 0.0028 0.0028 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.002 0.0119
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0136 0.0384 0.0689
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0022 0.0022
Trypanosoma brucei hexokinase, putative 0.0081 0.0202 0.1775
Giardia lamblia Kinase, STE STE20 0.0089 0.0229 0.0532
Leishmania major mitochondrial DNA polymerase beta 0.0355 0.1107 1
Schistosoma mansoni lipoxygenase 0.0496 0.1573 0.1571
Echinococcus granulosus CREB binding protein 0.013 0.0364 0.0364
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0047 0.0096
Leishmania major hypothetical protein, conserved 0.0025 0.002 0.0119
Treponema pallidum ATP-dependent DNA helicase 0.0038 0.006 0.0095
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0076 0.0629
Schistosoma mansoni hypothetical protein 0.003 0.0033 0.0031
Entamoeba histolytica hypothetical protein 0.0024 0.0014 0.0017
Brugia malayi hypothetical protein 0.0037 0.0058 0.0275
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0025 0.0018 0.0061
Loa Loa (eye worm) hypothetical protein 0.011 0.0298 0.1581
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0049 0.0097 0.0097
Trichomonas vaginalis cdc25b, putative 0.0138 0.039 0.0914
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0052 0.0261
Mycobacterium leprae PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRAN 0.0028 0.0028 0.0018
Loa Loa (eye worm) hypothetical protein 0.0109 0.0294 0.156
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0048 0.0095 0.0475
Echinococcus granulosus expressed protein 0.0048 0.0095 0.0095
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.0258 0.1354
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0089 0.0229 0.12
Loa Loa (eye worm) hypothetical protein 0.0138 0.039 0.2075
Echinococcus multilocularis thioredoxin glutathione reductase 0.0055 0.0118 0.0118
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.002 0.0264
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0022 0.0009 0.0009
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0335 0.178
Echinococcus granulosus caspase 0.0261 0.0798 0.0798
Brugia malayi mbt repeat family protein 0.0056 0.0121 0.0614
Brugia malayi photoreceptor-specific nuclear receptor 0.0055 0.0118 0.0602
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.006 0.0486
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.01 0.0266 0.4446
Echinococcus granulosus importin subunit beta 1 0.0029 0.0032 0.0032
Onchocerca volvulus 0.0469 0.1483 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0054 0.0114 0.021
Schistosoma mansoni tyrosine kinase 0.008 0.0201 0.0199
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.005 0.0737
Brugia malayi Bromodomain containing protein 0.0042 0.0075 0.037
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0315 0.0737
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Toxoplasma gondii flavoprotein subunit of succinate dehydrogenase 0.0025 0.0018 0.0195
Giardia lamblia Sgs1 DNA helicase, putative 0.0074 0.018 0.0413
Brugia malayi F/Y-rich N-terminus family protein 0.0042 0.0074 0.0361
Loa Loa (eye worm) hypothetical protein 0.0061 0.0136 0.0713
Schistosoma mansoni hypothetical protein 0.0032 0.0041 0.0039
Brugia malayi nuclear hormone receptor 0.0026 0.0022 0.0082
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0079 0.1238
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0016 0.0016
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit, putative 0.0038 0.006 0.0489
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0026 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0005
Mycobacterium ulcerans glutaminase 0.0277 0.085 0.1586
Schistosoma mansoni rotamase 0.0035 0.0052 0.0051
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0132 0.0372 0.0712
Schistosoma mansoni jumonji/arid domain-containing protein 0.0175 0.0513 0.0511
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0071 0.129
Leishmania major cathepsin L-like protease 0.0068 0.0158 0.138
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0028 0.005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0022 0.0026
Schistosoma mansoni ran 0.0022 0.0007 0.0005
Schistosoma mansoni hypothetical protein 0.0032 0.0041 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Leishmania major hypothetical protein, conserved 0.0028 0.0028 0.0192
Echinococcus multilocularis expressed protein 0.0378 0.1184 0.1184
Schistosoma mansoni hypothetical protein 0.0028 0.0028 0.0026
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.002 0.0073
Plasmodium falciparum histone acetyltransferase GCN5 0.0087 0.0224 0.4358
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.0258 0.164
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.0075 0.0075
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0099 0.0262 0.4373
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0007 0.0007
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0355 0.1107 1
Brugia malayi nuclear receptor RXR 0.0029 0.0032 0.0138
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0079 0.0657
Trypanosoma cruzi DNA polymerase eta, putative 0.0112 0.0305 0.2711
Loa Loa (eye worm) hypothetical protein 0.0106 0.0287 0.1521
Leishmania major hexokinase, putative 0.0081 0.0202 0.1775
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0036 0.0036
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0064 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.005 0.0391
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0055 0.0118 0.0616
Brugia malayi acetyltransferase, GNAT family protein 0.0329 0.102 0.5456
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0013 0.0015
Onchocerca volvulus 0.0111 0.0301 0.1933
Echinococcus multilocularis cpg binding protein 0.0106 0.0284 0.0284
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0099 0.022
Echinococcus multilocularis sterol regulatory element binding protein 0.005 0.0099 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0113 0.0309 0.2746
Loa Loa (eye worm) hypothetical protein 0.0106 0.0287 0.1521
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0023 0.0276
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0172 0.0505 0.8539
Giardia lamblia Kinase, CMGC MAPK 0.0115 0.0315 0.0737
Trypanosoma brucei metacaspase MCA3 0.0099 0.0262 0.2318
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.002 0.0029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0136 0.0383 0.3422
Loa Loa (eye worm) translation initiation factor 4E 0.0041 0.0069 0.0353
Mycobacterium leprae Probable thiosulfate sulfurtransferase SseA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) 0.0028 0.0028 0.0018
Echinococcus multilocularis bloom syndrome protein 0.0116 0.0319 0.0319
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.002 0.0046
Loa Loa (eye worm) hypothetical protein 0.0116 0.0317 0.1686
Loa Loa (eye worm) hypothetical protein 0.0086 0.0218 0.1154
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0118 0.0602
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0006 0.0002
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0133 0.0375 0.0375
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0172 0.0505 0.097
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0168 0.049 0.4393
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0028 0.0051
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0172 0.0505 0.4526
Schistosoma mansoni ap endonuclease 0.0042 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0038 0.006 0.0303
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0099 0.0262 0.0609
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0028 0.0028 0.0026
Echinococcus granulosus fetal alzheimer antigen falz 0.0032 0.0041 0.0041
Brugia malayi CXXC zinc finger family protein 0.0098 0.0259 0.1357
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0138 0.039 0.0914
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0002 0.0002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0151 0.0434 0.2313
Loa Loa (eye worm) TK/EGFR protein kinase 0.0151 0.0434 0.2314
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0475 0.0473
Schistosoma mansoni CREB-binding protein 2 0.013 0.0364 0.0362
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0169 0.0386
Giardia lamblia Kinase, PLK 0.0098 0.0258 0.06
Echinococcus granulosus mitogen activated protein kinase 0.0115 0.0315 0.0315
Echinococcus multilocularis mitogen activated protein kinase 0.0115 0.0315 0.0315
Echinococcus multilocularis protein dispatched 1 0.0057 0.0123 0.0123
Echinococcus multilocularis Polycystic kidney disease protein 0.0106 0.0287 0.0287
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0033 0.0455
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0138 0.039 0.0914
Mycobacterium tuberculosis Conserved hypothetical protein 0.0028 0.0028 0.0043
Schistosoma mansoni hypothetical protein 0.0584 0.1864 0.1863
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0158 0.138
Onchocerca volvulus Bile acid receptor homolog 0.0055 0.0118 0.0685
Giardia lamblia Hypothetical protein 0.0028 0.0028 0.005
Brugia malayi hypothetical protein 0.0025 0.002 0.0071
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0049 0.0097 0.0097
Brugia malayi nuclear receptor NHR-88 0.0055 0.0118 0.0602
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0005
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.0059 0.013 0.013
Loa Loa (eye worm) inositol-1 0.0043 0.0079 0.0404
Brugia malayi ecdysteroid receptor 0.0055 0.0118 0.0602
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0166 0.0166
Brugia malayi Niemann-Pick C1 protein precursor 0.0116 0.0317 0.1674
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0033 0.0158
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0049 0.0097 0.0097
Trypanosoma brucei DNA polymerase IV, putative 0.0172 0.0505 0.4526
Onchocerca volvulus Cell death protein 3 homolog 0.0222 0.0668 0.444
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0184
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0055 0.0118 0.0117
Echinococcus granulosus succinate dehydrogenase ubiquinone 0.0025 0.0018 0.0018
Echinococcus granulosus tumor protein p63 0.0755 0.2426 0.2426
Echinococcus granulosus hexokinase type 2 0.0081 0.0202 0.0202
Leishmania major hypothetical protein, unknown function 0.0028 0.0028 0.0192
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.0022 0.0022
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0054 0.0114 0.0255
Giardia lamblia Fructose-bisphosphate aldolase 0.1292 0.4198 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.0009 0.0007
Loa Loa (eye worm) MBCTL1 0.0064 0.0146 0.0766
Plasmodium vivax iron-sulfur subunit of succinate dehydrogenase, putative 0.0059 0.013 0.248
Trichomonas vaginalis sucrase-isomaltase, putative 0.0042 0.0076 0.0165
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0138 0.039 0.0914
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit 0.0033 0.0043 0.0333
Echinococcus granulosus protein quaking 0.0032 0.0041 0.0041
Leishmania major DNA polymerase kappa, putative 0.0027 0.0024 0.0157
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0038 0.0063 0.1124
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0099 0.0262 0.0609
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0138 0.039 0.039
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0049 0.0097 0.0095
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0047 0.0096
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0099 0.0262 0.0609
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0056 0.0121 0.0701
Trypanosoma brucei DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0023 0.0038
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0016 0.0016
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0032 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0074 0.018 0.018
Echinococcus granulosus lipoxygenase domain containing protein 0.0106 0.0287 0.0287
Trypanosoma cruzi metacaspase, putative 0.0099 0.0262 0.2318
Brugia malayi Thioredoxin reductase 0.0055 0.0116 0.0589
Echinococcus multilocularis JmjC domain containing protein 4 0.0045 0.0083 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0055 0.0118 0.0616
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0055 0.0118 0.0602
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0076 0.0165
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0425
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.0361
Trypanosoma brucei unspecified product 0.0059 0.0132 0.1136
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0066 0.0142
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0074 0.1359
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0258 0.0256
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.158 0.515 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Schistosoma mansoni hypothetical protein 0.1394 0.4537 0.4536
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0191 0.0567 0.303
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0584 0.1864 0.1864
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0079 0.0079
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0089 0.0229 0.2025
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.0364
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0258 0.06
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0631 0.2018 0.3781
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0616
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Leishmania major DNA polymerase kappa, putative 0.0108 0.029 0.258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0055 0.0118 0.0602
Echinococcus multilocularis dual specificity mitogen activated protein 0.0089 0.0229 0.0229
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0208 0.0621 0.0619
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0329 0.102 0.102
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0616
Trichomonas vaginalis rotamase, putative 0.0035 0.005 0.0103
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0028 0.0028 0.0043
Brugia malayi translation initiation factor 4E 0.0041 0.0069 0.0338
Onchocerca volvulus 0.0138 0.039 0.2538
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.002 0.0124
Loa Loa (eye worm) hypothetical protein 0.0153 0.044 0.2344
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0129
Schistosoma mansoni Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specificprotein A14 protein) 0.0028 0.0028 0.0026
Echinococcus granulosus snurportin 1 0.0312 0.0965 0.0965
Onchocerca volvulus 0.0138 0.039 0.2538
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.0144 0.1253
Schistosoma mansoni hypothetical protein 0.0312 0.0965 0.0963
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0007 0.002
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0111 0.0947
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0138 0.039 0.0914
Mycobacterium ulcerans thiosulfate sulfurtransferase SseA 0.0028 0.0028 0.0042
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0228 0.0688 0.0688
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.002 0.0233
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1292 0.4198 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0136 0.0384 0.0735
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0047 0.0096
Trypanosoma cruzi NADH dehydrogenase, putative 0.0038 0.0063 0.0509
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0041 0.0069 0.015
Echinococcus granulosus CREB binding protein 0.0084 0.0213 0.0213
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0049 0.0097 0.0095
Echinococcus granulosus hexokinase 0.0081 0.0202 0.0202
Giardia lamblia Histone acetyltransferase GCN5 0.0087 0.0224 0.0518
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0115 0.0315 0.2808
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0115 0.0315 0.5296
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.013 0.0364 0.0362
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0616
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.002 0.0273
Echinococcus granulosus peregrin 0.0042 0.0075 0.0075
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.0022 0.0022
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0007 0.002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0106 0.0287 0.0287
Schistosoma mansoni tyrosine kinase 0.0048 0.0095 0.0093
Echinococcus multilocularis SAM and MBT domain containing protein 0.0056 0.0121 0.0121
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0132 0.0372 0.0372
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.0153
Echinococcus granulosus JmjC domain containing protein 4 0.0045 0.0083 0.0083
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0136 0.0384 0.0735
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0029 0.0032 0.003
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0038 0.0063 0.1124
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0074 0.018 0.3478
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0005
Leishmania major DNA polymerase eta, putative 0.0053 0.0109 0.0931
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0041 0.0069 0.1077
Echinococcus granulosus transcription factor Dp 1 0.004 0.0069 0.0069
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.0258 0.06
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0083 0.0425
Plasmodium vivax DNA repair protein REV1, putative 0.0027 0.0024 0.0346
Schistosoma mansoni hypothetical protein 0.0048 0.0094 0.0092
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.002 0.0124
Brugia malayi indoleamine 2,3-dioxygenase 0.0584 0.1864 1
Loa Loa (eye worm) bromodomain containing protein 0.0031 0.0037 0.018
Schistosoma mansoni DNA polymerase IV / kappa 0.0027 0.0024 0.0022
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0074 0.018 0.0932
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0158
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0047 0.0096
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0115 0.0315 0.2808
Loa Loa (eye worm) hypothetical protein 0.011 0.03 0.1593
Brugia malayi jmjC domain containing protein 0.0045 0.0083 0.041
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0138 0.039 0.039
Loa Loa (eye worm) hypothetical protein 0.0123 0.0342 0.182
Loa Loa (eye worm) thioredoxin reductase 0.0055 0.0116 0.0604
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0258 0.06
Brugia malayi hexokinase 0.0081 0.0202 0.1052
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0113 0.0309 0.2746
Echinococcus multilocularis caspase 8 0.0099 0.0262 0.0262
Trypanosoma brucei DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Brugia malayi nuclear receptor NHR-88 0.0026 0.0022 0.0082
Echinococcus granulosus lysine specific demethylase 5A 0.0175 0.0513 0.0513
Echinococcus granulosus hexokinase 0.0081 0.0202 0.0202
Brugia malayi MAP kinase sur-1 0.0115 0.0315 0.1663
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.0144 0.1253
Toxoplasma gondii hypothetical protein 0.0057 0.0124 0.2022
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.005 0.0103
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0136 0.0383 0.0383
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0616
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.002 0.0032
Leishmania major hexokinase, putative 0.0081 0.0202 0.1775
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0055 0.0118 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0005
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0074 0.0364
Echinococcus granulosus succinate dehydrogenase (ubiquinone) iron sulfur 0.0059 0.013 0.013
Brugia malayi Importin beta-1 subunit 0.0029 0.0032 0.0137
Echinococcus multilocularis expressed conserved protein 0.0109 0.0294 0.0294
Entamoeba histolytica rodhanase-like domain containing protein 0.0138 0.039 0.0914
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0042 0.0076 0.0388
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0063 0.0144 0.1253
Onchocerca volvulus 0.0051 0.0103 0.0578
Schistosoma mansoni DNA polymerase eta 0.0112 0.0305 0.0303
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0129
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0007 0.0007
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0166 0.0166
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0169 0.0886
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0054 0.0114 0.1834
Brugia malayi tumor suppressor. 0.0378 0.1183 0.6332
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0099 0.0262 0.1373
Schistosoma mansoni DNA helicase recq1 0.0074 0.018 0.0178
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0304 0.058
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1634 0.5328 1
Loa Loa (eye worm) hexokinase 0.0051 0.0103 0.0532
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0118 0.0118
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0041 0.0071 0.1102
Entamoeba histolytica rodhanase-like domain containing protein 0.0028 0.0028 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0076 0.0165
Echinococcus multilocularis thyroid hormone receptor alpha 0.0189 0.0558 0.0558
Echinococcus multilocularis apoptotic protease activating factor 1 0.0123 0.0342 0.0342
Echinococcus multilocularis insulin receptor 0.0048 0.0095 0.0095
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0123 0.0341 0.0609
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.005 0.0099 0.0515
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.002 0.0124
Trypanosoma brucei polo-like protein kinase 0.0098 0.0258 0.2286
Echinococcus granulosus flap endonuclease 1 0.0026 0.0023 0.0023
Schistosoma mansoni kinase 0.0051 0.0103 0.0101
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.002 0.002
Onchocerca volvulus 0.0028 0.0028 0.0066
Schistosoma mansoni hypothetical protein 0.0028 0.0028 0.0026
Leishmania major phosphoglycerate kinase C, glycosomal 0.0172 0.0505 0.4526
Echinococcus multilocularis epidermal growth factor receptor 0.0081 0.0203 0.0203
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0258 0.06
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0118 0.0118
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0079 0.0172
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0055 0.0118 0.0118
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0054 0.0114 0.0114
Schistosoma mansoni hypothetical protein 0.0028 0.0028 0.0026
Echinococcus multilocularis neutral alpha glucosidase AB 0.0042 0.0076 0.0076
Trichomonas vaginalis STE family protein kinase 0.0089 0.0229 0.0532
Schistosoma mansoni chromobox protein 0.0071 0.0169 0.0167
Echinococcus multilocularis hexokinase 0.0081 0.0202 0.0202
Mycobacterium ulcerans hypothetical protein 0.0028 0.0028 0.0042
Trypanosoma cruzi NADH dehydrogenase, putative 0.0038 0.0063 0.0509
Entamoeba histolytica hexokinase 2 0.0081 0.0202 0.0466
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0076 0.0165
Schistosoma mansoni inositol monophosphatase 0.0043 0.0079 0.0077
Echinococcus granulosus epidermal growth factor receptor 0.0081 0.0203 0.0203
Brugia malayi Bromodomain containing protein 0.0104 0.0278 0.1461
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0172 0.0505 1
Schistosoma mansoni ran 0.0022 0.0007 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0022 0.0022
Echinococcus multilocularis neuropeptide s receptor 0.0544 0.1729 0.1729
Leishmania major hypothetical protein, conserved 0.0028 0.0028 0.0192
Schistosoma mansoni nuclear receptor 0.0026 0.0022 0.002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0132 0.0372 0.0689
Schistosoma mansoni cpg binding protein 0.0106 0.0284 0.0283
Brugia malayi Hexokinase family protein 0.0025 0.0018 0.0062
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0099 0.0262 0.026
Entamoeba histolytica hypothetical protein 0.0028 0.0028 0.005
Loa Loa (eye worm) hexokinase 0.0081 0.0202 0.1066
Schistosoma mansoni flap endonuclease-1 0.0024 0.0014 0.0013
Mycobacterium tuberculosis Conserved protein 0.0028 0.0028 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0055 0.0118 0.0602
Brugia malayi Furin-like cysteine rich region family protein 0.0151 0.0434 0.2302
Onchocerca volvulus Hexokinase homolog 0.0051 0.0103 0.0578
Plasmodium falciparum glutathione reductase 0.0055 0.0116 0.2198
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0616
Echinococcus multilocularis hexokinase type 2 0.0081 0.0202 0.0202
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0054 0.0114 0.2148
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0022 0.0082
Echinococcus multilocularis lysine specific demethylase 5A 0.0167 0.0487 0.0487
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0076 0.0629
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0139 0.1205
Schistosoma mansoni polycystin 1-related 0.0106 0.0287 0.0285
Brugia malayi Bloom's syndrome protein homolog 0.0116 0.0319 0.1683
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0014 0.0017
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0083 0.0209 0.1836
Loa Loa (eye worm) hypothetical protein 0.0124 0.0344 0.1831
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0086 0.022 0.1161
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.0116 0.0995
Echinococcus granulosus RUN 0.0106 0.0287 0.0287
Echinococcus granulosus expressed protein 0.0035 0.0052 0.0052
Trypanosoma brucei unspecified product 0.0059 0.0132 0.1136
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0045 0.0083 0.1305
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0054 0.0114 0.0114
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0033 0.0043 0.0333
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0086 0.022 0.022
Echinococcus granulosus expressed conserved protein 0.0109 0.0294 0.0294
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0055 0.0118 0.0118
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.0258 0.0258
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0054 0.0114 0.021
Brugia malayi hypothetical protein 0.0032 0.0041 0.0186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Echinococcus granulosus histone lysine methyltransferase setb 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.0076 0.0165
Echinococcus granulosus muscleblind protein 0.0151 0.0434 0.0434
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0041 0.0069 0.015
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0054 0.0114 0.018
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0024 0.0157
Echinococcus granulosus SAM and MBT domain containing protein 0.0056 0.0121 0.0121
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseA (rhodanese) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase) 0.0028 0.0028 0.0043
Leishmania major hypothetical protein, conserved 0.0028 0.0028 0.0192
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0163 0.0475 0.2532
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0201
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0329 0.102 0.1019
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0055 0.0118 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0028 0.005
Brugia malayi ImpB/MucB/SamB family protein 0.0086 0.022 0.1148
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0054 0.0114 0.0576
Brugia malayi polk-prov protein 0.0113 0.0309 0.1626
Plasmodium falciparum phosphoglycerate kinase 0.0172 0.0505 1
Trypanosoma cruzi metacaspase, putative 0.0099 0.0262 0.2318
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0355 0.1107 1
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0172 0.0505 0.1188
Brugia malayi Phosphoglycerate kinase 0.0063 0.0144 0.0742
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0115 0.0315 0.2808
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0168 0.049 0.4393
Brugia malayi conserved hypotetical protein 0.0026 0.0022 0.0082
Giardia lamblia Hypothetical protein 0.0028 0.0028 0.005
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Schistosoma mansoni alpha-glucosidase 0.0165 0.0479 0.0478
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0133 0.0375 0.0375
Mycobacterium tuberculosis Probable succinate dehydrogenase (flavoprotein subunit) SdhA (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogena 0.0025 0.0018 0.0024
Loa Loa (eye worm) succinate-ubiquinone oxidoreductase 0.0025 0.0018 0.0077
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0032 0.0436
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0025 0.0018 0.0024
Echinococcus granulosus zinc finger protein 0.0039 0.0063 0.0063
Treponema pallidum hexokinase (hxk) 0.0081 0.0202 0.0435
Brugia malayi hypothetical protein 0.0037 0.0058 0.0275
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0089 0.0229 0.1213
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.002 0.0119
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0172 0.0505 0.1188
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0129
Schistosoma mansoni hypothetical protein 0.0172 0.0502 0.05
Loa Loa (eye worm) hypothetical protein 0.0183 0.054 0.288
Trichomonas vaginalis cdc25a, putative 0.0028 0.0028 0.005
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.0022 0.0097
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0163 0.0475 0.0475
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1292 0.4198 1
Schistosoma mansoni thyroid hormone receptor 0.0189 0.0558 0.0556
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0262 0.0609
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0055 0.0118 0.0616
Echinococcus granulosus caspase 2 0.0222 0.0668 0.0668
Wolbachia endosymbiont of Brugia malayi sulfurtransferase 0.0028 0.0028 0.02
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0048 0.0094 0.1507
Loa Loa (eye worm) hexokinase 0.0081 0.0202 0.1066
Echinococcus multilocularis succinate dehydrogenase iron sulfur protein 0.0033 0.0043 0.0043
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0022 0.0022
Echinococcus granulosus insulin receptor 0.0048 0.0095 0.0095
Echinococcus multilocularis caspase 3 0.0162 0.0472 0.0472
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.0258 0.2286
Loa Loa (eye worm) succinate dehydrogenase iron-sulfur protein 0.0059 0.013 0.068
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.002 0.0273
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0024 0.0157
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0071 0.0349
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1292 0.4198 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0076 0.0165
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0168 0.049 0.4393
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0055 0.0118 0.0685
Brugia malayi hypothetical protein 0.0469 0.1483 0.7948
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0584 0.1864 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0053 0.0109 0.0931
Schistosoma mansoni protein kinase 0.0089 0.0229 0.0228
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0163 0.0475 0.3118
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0054 0.0114 0.0203
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0041 0.0069 0.0571
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1292 0.4198 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0115 0.0315 0.1676
Echinococcus multilocularis jumonji domain containing 1A 0.0045 0.0083 0.0083
Echinococcus multilocularis phd:f box containing protein 0.0045 0.0083 0.0083
Plasmodium vivax multidomain scavenger receptor, putative 0.0106 0.0287 0.5623
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0022 0.002
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0066 0.0142
Schistosoma mansoni cpg binding protein 0.0106 0.0284 0.0283
Echinococcus multilocularis tRNA 2 selenouridine synthase 0.0028 0.0028 0.0028
Plasmodium falciparum importin beta, putative 0.0029 0.0032 0.0511
Trichomonas vaginalis DNA helicase recq, putative 0.0083 0.0209 0.0482
Trypanosoma brucei phosphoglycerate kinase 0.0172 0.0505 0.4526
Echinococcus granulosus histone acetyltransferase KAT2B 0.0315 0.0974 0.0974
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0055 0.0118 0.0117
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0025 0.0018 0.0061
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0304 0.058
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.0022 0.0082
Loa Loa (eye worm) CXXC zinc finger family protein 0.0098 0.0259 0.1371
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0134 0.0702
Mycobacterium ulcerans aldehyde dehydrogenase 0.0136 0.0383 0.071
Plasmodium vivax phosphoglycerate kinase, putative 0.0172 0.0505 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0298 0.1581
Schistosoma mansoni ubiquitin-activating enzyme E1C 0.0028 0.0028 0.0026
Onchocerca volvulus 0.0056 0.0121 0.0701
Schistosoma mansoni zinc finger protein 0.0039 0.0063 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0129
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0041 0.0069 0.015
Schistosoma mansoni nuclear receptor 0.0026 0.0022 0.002
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.0144 0.1253
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1634 0.5328 1
Loa Loa (eye worm) DR-78 0.0026 0.0022 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.0009 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0055 0.0118 0.0602
Plasmodium vivax mitogen-activated protein kinase phosphatase 1, putative 0.0028 0.0028 0.0424
Echinococcus granulosus dual specificity mitogen activated protein 0.0089 0.0229 0.0229
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0166 0.0859
Echinococcus multilocularis snurportin 1 0.0312 0.0965 0.0965
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0016 0.0016
Plasmodium falciparum glutathione reductase 0.0026 0.002 0.0273
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0026 0.002 0.0028
Brugia malayi Hexokinase family protein 0.0051 0.0103 0.0517
Echinococcus granulosus geminin 0.0172 0.0502 0.0502
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.005 0.01 0.0852
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0118 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0007 0.0006
Brugia malayi hypothetical protein 0.0123 0.0342 0.1808
Schistosoma mansoni hypothetical protein 0.0048 0.0094 0.0092
Entamoeba histolytica rodhanase-like domain containing protein 0.0138 0.039 0.0914
Wolbachia endosymbiont of Brugia malayi succinate dehydrogenase iron-sulfur subunit 0.0059 0.013 0.2305
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0616
Loa Loa (eye worm) mbt repeat family protein 0.0056 0.0121 0.0628
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0007 0.0005
Schistosoma mansoni caspase-7 (C14 family) 0.0261 0.0798 0.0796
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0099 0.0262 0.4373
Giardia lamblia Thiosulfate sulfurtransferase 0.0028 0.0028 0.005
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0086 0.0219 0.0219
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0099 0.0262 0.0609
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0056 0.0121 0.0119
Leishmania major hypothetical protein, conserved 0.0028 0.0028 0.0192
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0041 0.0069 0.0068
Echinococcus multilocularis chromobox protein 1 0.0071 0.0169 0.0169
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.0144 0.1253
Mycobacterium tuberculosis Probable fumarate reductase [iron-sulfur subunit] FrdB (fumarate dehydrogenase) (fumaric hydrogenase) 0.0033 0.0043 0.0073
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0028 0.005
Trichomonas vaginalis bromodomain-containing protein, putative 0.01 0.0266 0.0619
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0028 0.0192
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0022 0.0026
Mycobacterium ulcerans DNA polymerase IV 0.0172 0.0505 0.0938
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0172 0.0505 0.0917
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0024 0.0157
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0089
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Brugia malayi Temporarily assigned gene name protein 44 0.0032 0.0041 0.0186
Toxoplasma gondii succinate dehydrogenase [ubiquinone] iron-sulfur protein 0.0059 0.013 0.2118
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0138 0.039 0.0388
Plasmodium vivax hypothetical protein, conserved 0.0099 0.0262 0.5121
Loa Loa (eye worm) steroid hormone receptor 0.0055 0.0118 0.0616
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0086 0.0219 0.0219
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.0258 0.1368
Mycobacterium tuberculosis Probable molybdenum cofactor biosynthesis protein MoeB2 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase) 0.0028 0.0028 0.0043
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.002 0.0264
Echinococcus multilocularis zinc finger protein 0.0039 0.0063 0.0063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1292 0.4198 1
Brugia malayi MoeZ/MoeB domain containing protein 0.0028 0.0028 0.0114
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0052 0.0108 0.0108
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0076 0.0397
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.0022 0.002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0066 0.0329
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.0153
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0089 0.0229 0.2025
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0262 0.0609
Entamoeba histolytica rodhanase-like domain containing protein 0.0028 0.0028 0.005
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0045 0.0083 0.0692
Entamoeba histolytica recQ family DNA helicase 0.0038 0.006 0.0128
Loa Loa (eye worm) glutaminase 0.0277 0.085 0.4547
Loa Loa (eye worm) TK/INSR protein kinase 0.0048 0.0095 0.0491
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.002 0.0124
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0079 0.0657
Schistosoma mansoni hypothetical protein 0.0024 0.0016 0.0014
Mycobacterium tuberculosis Probable reductase 0.0112 0.0304 0.058
Toxoplasma gondii thioredoxin reductase 0.0055 0.0116 0.1877
Echinococcus multilocularis FTZ F1 alpha 0.0055 0.0118 0.0118
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0079 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0315 0.0314
Schistosoma mansoni loxhd1 0.0106 0.0287 0.0285
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0074 0.018 0.0947
Brugia malayi chromobox protein homolog 3 0.004 0.0066 0.0321
Onchocerca volvulus 0.0106 0.0287 0.1834
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.005 0.0391
Leishmania major succinate dehydrogenase flavoprotein, putative 0.0025 0.0018 0.0103
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0355 0.1107 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0055 0.0118 0.0602
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0074 0.0615
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.002 0.0124
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.005 0.01 0.0852
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0074 0.0615
Schistosoma mansoni retinoic acid receptor RXR 0.0055 0.0118 0.0117
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0166 0.1451
Plasmodium falciparum iron-sulfur subunit of succinate dehydrogenase 0.0059 0.013 0.248
Echinococcus multilocularis CREB binding protein 0.0092 0.024 0.024
Leishmania major hypothetical protein, conserved 0.0033 0.0043 0.0333
Toxoplasma gondii aldehyde dehydrogenase 0.0136 0.0383 0.6456
Schistosoma mansoni sex comb on midleg homolog 0.0056 0.0121 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1292 0.4198 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0166 0.0381
Echinococcus multilocularis geminin 0.0172 0.0502 0.0502
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.0033 0.0043 0.0041
Entamoeba histolytica hexokinase 1 0.0081 0.0202 0.0466
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.002 0.0124
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0054 0.0114 0.0972
Schistosoma mansoni coup transcription factor 0.0055 0.0118 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.002 0.0124
Brugia malayi hypothetical protein 0.0106 0.0287 0.1508
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0041 0.0069 0.0571
Brugia malayi jmjC domain containing protein 0.0045 0.0083 0.041
Echinococcus granulosus neutral alpha glucosidase AB 0.0042 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.004 0.0066 0.0336
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0123 0.0341 0.0653
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0071 0.0346
Plasmodium falciparum flavoprotein subunit of succinate dehydrogenase 0.0025 0.0018 0.0228
Plasmodium vivax metacaspase 1, putative 0.0099 0.0262 0.5121
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0262 0.0609
Brugia malayi Bromodomain containing protein 0.0055 0.0117 0.0596
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0014 0.0017
Schistosoma mansoni succinate dehydrogenase 0.0025 0.0018 0.0016
Onchocerca volvulus 0.0031 0.0038 0.0137
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0055 0.0118 0.0118
Loa Loa (eye worm) hexokinase type II 0.0081 0.0202 0.1066
Brugia malayi Doublecortin family protein 0.0106 0.0287 0.1508
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0047 0.0096
Mycobacterium ulcerans aldehyde dehydrogenase 0.0136 0.0383 0.071
Schistosoma mansoni bromodomain containing protein 0.009 0.0232 0.0231
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0023 0.0146
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0032 0.0041 0.004
Onchocerca volvulus 0.0081 0.0202 0.1256
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0118 0.0118
Echinococcus granulosus sterol regulatory element binding protein 0.005 0.0099 0.0099
Plasmodium falciparum metacaspase 1 0.0099 0.0262 0.5121
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0496 0.1573 0.1573
Schistosoma mansoni importin beta-1 0.0029 0.0032 0.003
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0118 0.0323 0.0322
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0048 0.0095 0.0095
Schistosoma mansoni ubiquitin-activating enzyme E1 0.0028 0.0028 0.0026
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0014 0.0066
Brugia malayi MH2 domain containing protein 0.0121 0.0335 0.1767
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0028 0.0028 0.005
Loa Loa (eye worm) doublecortin family protein 0.0106 0.0287 0.1521
Schistosoma mansoni hypothetical protein 0.0028 0.0028 0.0026
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0099 0.0262 0.0609
Schistosoma mansoni blooms syndrome DNA helicase 0.0079 0.0195 0.0193
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0022 0.0022
Schistosoma mansoni alpha glucosidase 0.0042 0.0076 0.0074
Echinococcus granulosus neuropeptide receptor A26 0.0544 0.1729 0.1729
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0118 0.0602
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0081 0.0203 0.0203
Echinococcus multilocularis protein quaking 0.0032 0.0041 0.0041
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0041 0.0069 0.015
Schistosoma mansoni rab6-interacting 0.0106 0.0287 0.0285
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0074 0.0134
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.002 0.0124
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.0022 0.0082
Loa Loa (eye worm) hypothetical protein 0.0151 0.0434 0.2313
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0172 0.0505 0.1188
Onchocerca volvulus 0.0138 0.039 0.2538
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0049 0.0097 0.0215
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Schistosoma mansoni RAR-like nuclear receptor 0.0055 0.0118 0.0117
Trypanosoma brucei unspecified product 0.0151 0.0434 0.3884
Leishmania major cathepsin L-like protease 0.0068 0.0158 0.138
Toxoplasma gondii hexokinase 0.0081 0.0202 0.3349
Leishmania major NADH dehydrogenase, putative 0.0038 0.0063 0.0509
Echinococcus multilocularis hexokinase 0.0081 0.0202 0.0202
Onchocerca volvulus 0.0026 0.0022 0.0026
Toxoplasma gondii rhodanese family domain-containing protein 0.0028 0.0028 0.0362
Echinococcus granulosus lysosomal alpha glucosidase 0.0191 0.0567 0.0567
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.0059 0.013 0.013
Echinococcus multilocularis phosphoglycerate kinase 1 0.0172 0.0505 0.0505
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0315 0.2808
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0045 0.0083 0.0692
Loa Loa (eye worm) hypothetical protein 0.0138 0.039 0.2075
Echinococcus multilocularis protein patched 0.005 0.0099 0.0099
Echinococcus granulosus mitogen activated protein kinase 3 0.0115 0.0315 0.0315
Trypanosoma brucei DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Toxoplasma gondii histone lysine methyltransferase SET1 0.0198 0.059 1
Echinococcus granulosus FTZ F1 alpha 0.0055 0.0118 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0099 0.0222
Echinococcus granulosus phd:f box containing protein 0.0045 0.0083 0.0083
Brugia malayi Phosphoglycerate kinase 0.0172 0.0505 0.2681
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.0038 0.006 0.006
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0048 0.0095 0.0093
Mycobacterium leprae PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE) 0.0028 0.0028 0.0018
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.002 0.0018
Schistosoma mansoni hypothetical protein 0.0349 0.1088 0.1087
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0132 0.0372 0.332
Trypanosoma cruzi DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Plasmodium vivax hypothetical protein, conserved 0.003 0.0033 0.0532
Schistosoma mansoni blooms syndrome DNA helicase 0.0038 0.006 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0076 0.0165
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.002 0.0032
Brugia malayi Heterochromatin protein 1 0.0071 0.0169 0.0872
Brugia malayi steroid hormone receptor 0.0055 0.0118 0.0602
Trypanosoma brucei DNA damage repair protein, putative 0.0027 0.0024 0.0157
Echinococcus granulosus transcription factor eb 0.0109 0.0296 0.0296
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0028 0.0028 0.005
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0038 0.0063 0.0107
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0053 0.0109 0.1755
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0097 0.05
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0074 0.0379
Trypanosoma brucei mercaptopyruvate sulfurtransferase, putative 0.0028 0.0028 0.0192
Echinococcus multilocularis ecdysone induced protein 78C 0.0055 0.0118 0.0118
Entamoeba histolytica recQ family helicase, putative 0.0036 0.0055 0.0116
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0074 0.0129
Brugia malayi hypothetical protein 0.0026 0.0022 0.0082
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0049 0.0097 0.0097
Plasmodium falciparum DNA repair protein REV1, putative 0.0027 0.0024 0.0346
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0032 0.0231
Schistosoma mansoni inositol monophosphatase 0.0043 0.0079 0.0077
Trypanosoma brucei phosphoglycerate kinase, putative 0.0063 0.0144 0.1253
Loa Loa (eye worm) jmjC domain-containing protein 0.0175 0.0513 0.2737
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0027 0.0024 0.0295
Plasmodium vivax importin-beta 2, putative 0.0029 0.0032 0.0511
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0079 0.0079
Echinococcus multilocularis lysine specific demethylase 6a 0.0045 0.0083 0.0083
Echinococcus multilocularis dnaJ subfamily B 0.1394 0.4537 0.4537
Echinococcus multilocularis peregrin 0.0042 0.0075 0.0075
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0315 0.0737
Schistosoma mansoni rab6-interacting 0.0106 0.0287 0.0285
Brugia malayi glutaminase DH11.1 0.0277 0.085 0.4538
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0016 0.0064
Echinococcus granulosus Niemann Pick C1 protein 0.0116 0.0317 0.0317
Schistosoma mansoni steroid hormone receptor ad4bp 0.0055 0.0118 0.0117
Trichomonas vaginalis STE family protein kinase 0.0089 0.0229 0.0532
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0026 0.002 0.0028
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0038 0.0063 0.096
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0054 0.0114 0.0112
Brugia malayi Steroid receptor seven-up type 2 0.0055 0.0118 0.0602
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0123 0.0341 0.0653
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0041 0.0069 0.015
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0023 0.0038
Mycobacterium ulcerans phosphoglycerate kinase 0.0172 0.0505 0.0938
Trypanosoma brucei DNA polymerase eta, putative 0.0112 0.0305 0.2711
Toxoplasma gondii exonuclease III APE 0.0042 0.0074 0.116
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0258 0.2286
Echinococcus granulosus neuropeptide s receptor 0.0544 0.1729 0.1729
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.002 0.0124
Onchocerca volvulus Protein ultraspiracle homolog 0.0055 0.0118 0.0685
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0028 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0055 0.0118 0.0616
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0054 0.0114 0.0972
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0166 0.1451
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0099 0.0262 0.4373
Mycobacterium tuberculosis Conserved hypothetical protein 0.0187 0.0553 0.1064
Brugia malayi Rhodanese-like domain containing protein 0.0028 0.0028 0.0114
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0335 0.178
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0048 0.0095 0.1514
Echinococcus granulosus bloom syndrome protein 0.0116 0.0319 0.0319
Loa Loa (eye worm) RecQ helicase 0.0116 0.0319 0.1696
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0118 0.0602
Loa Loa (eye worm) hypothetical protein 0.0066 0.0152 0.08
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0055 0.0118 0.0616
Schistosoma mansoni hexokinase 0.0081 0.0202 0.02
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.0022 0.0082
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.002 0.0273
Leishmania major succinate dehydrogenase, putative 0.0038 0.006 0.0489
Echinococcus granulosus dna polymerase eta 0.0112 0.0305 0.0305
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.002 0.0124
Loa Loa (eye worm) hypothetical protein 0.0056 0.0121 0.0628
Plasmodium falciparum phd finger protein, putative 0.003 0.0033 0.0532
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0055 0.0118 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1292 0.4198 1
Onchocerca volvulus Alhambra homolog 0.003 0.0033 0.0103
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0055 0.0118 0.0117
Loa Loa (eye worm) hypothetical protein 0.0099 0.0262 0.1387
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0106 0.0287 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0028 0.005
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0032 0.0138
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.01 0.0266 0.0619
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0061 0.0136 0.1179
Trypanosoma brucei chrX additional, unordered contigs 0.0027 0.0024 0.0157
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0115 0.0315 0.2808
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.002 0.0124
Schistosoma mansoni hypothetical protein 0.0584 0.1864 0.1863
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0039 0.0064 0.0114
Echinococcus multilocularis muscleblind protein 0.0151 0.0434 0.0434
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0016 0.0016
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0132 0.0372 0.0372
Loa Loa (eye worm) hypothetical protein 0.0113 0.0309 0.1639
Schistosoma mansoni jumonji domain containing protein 0.0208 0.0623 0.0621
Schistosoma mansoni cpg binding protein 0.0098 0.0259 0.0257
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.002 0.0233
Echinococcus multilocularis histone acetyltransferase MYST2 0.0064 0.0146 0.0146
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.0022 0.0097
Trypanosoma brucei phosphoglycerate kinase 0.0063 0.0144 0.1253
Brugia malayi CHE-14 protein 0.005 0.0099 0.05
Brugia malayi hypothetical protein 0.0124 0.0344 0.1818
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0023 0.0146
Onchocerca volvulus 0.0106 0.0287 0.1834
Schistosoma mansoni phosphatidylserine receptor 0.0045 0.0083 0.0081
Giardia lamblia PHD finger protein 15 0.003 0.0033 0.0063
Onchocerca volvulus Huntingtin homolog 0.0124 0.0344 0.2228
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0071 0.0171 0.3296
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0014 0.0017
Schistosoma mansoni bromodomain containing protein 0.0021 0.0004 0.0002
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0038 0.0063 0.096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0049 0.0097 0.0215
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.0022 0.0022
Trypanosoma brucei DNA polymerase beta thumb, putative 0.005 0.01 0.0852
Mycobacterium leprae Conserved hypothetical protein 0.0028 0.0028 0.0018
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0049 0.0097 0.082
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0023 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Leishmania major As/Sb Reductase 0.0028 0.0028 0.0192
Echinococcus granulosus chromobox protein 1 0.0071 0.0169 0.0169
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0083 0.0209 0.1836
Echinococcus multilocularis hexokinase 0.0081 0.0202 0.0202
Echinococcus granulosus heat shock protein 67b2 0.0028 0.0028 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0022 0.0022
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0055 0.0118 0.0117
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0099 0.0262 0.0609
Loa Loa (eye worm) hypothetical protein 0.0124 0.0344 0.1831
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Treponema pallidum phosphoglycerate kinase 0.0172 0.0505 0.116
Echinococcus granulosus dnaJ subfamily B 0.1394 0.4537 0.4537
Echinococcus multilocularis chromobox protein 1 0.0071 0.0169 0.0169
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0054 0.0114 0.0255
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0115 0.0315 0.2808
Chlamydia trachomatis phosphoglycerate kinase 0.0172 0.0505 1
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0054 0.0114 0.0591
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0079 0.0657
Brugia malayi Glycosyl hydrolases family 31 protein 0.0191 0.0567 0.302
Echinococcus multilocularis Niemann Pick C1 protein 0.0165 0.0481 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0015
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0166 0.0874
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0024 0.0157
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0023 0.0023
Schistosoma mansoni patched 1 0.005 0.0099 0.0098
Loa Loa (eye worm) runx1 0.0059 0.013 0.0677
Loa Loa (eye worm) hypothetical protein 0.0172 0.0505 0.2693
Schistosoma mansoni ap endonuclease 0.0042 0.0074 0.0073
Plasmodium vivax glutathione reductase, putative 0.0055 0.0116 0.2198
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0258 0.06
Echinococcus multilocularis Rhodanese 0.0028 0.0028 0.0028
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0029 0.0032 0.0032
Schistosoma mansoni thyroid hormone receptor 0.0189 0.0558 0.0556
Leishmania major cathepsin L-like protease 0.0068 0.0158 0.138
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0032 0.003
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0074 0.0129
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Loa Loa (eye worm) tumor suppressor 0.0378 0.1183 0.6338
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0005
Chlamydia trachomatis succinate dehydrogenase iron sulfur subunit 0.0033 0.0043 0.0519
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0158 0.138
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.007 0.0166 0.2733
Schistosoma mansoni tyrosine kinase 0.0081 0.0203 0.0202
Brugia malayi Flap endonuclease-1 0.0026 0.0023 0.0087
Leishmania major DNA polymerase eta, putative 0.0112 0.0305 0.2711
Loa Loa (eye worm) glutaminase 2 0.0277 0.085 0.4547
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0109 0.0296 0.1556
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.0022 0.0082
Schistosoma mansoni caspase-3 (C14 family) 0.0261 0.0798 0.0796
Mycobacterium leprae Probable succinate dehydrogenase (iron-sulfur protein subunit) SdhB (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHY 0.0033 0.0043 0.0048
Leishmania major alpha glucosidase II subunit, putative 0.0042 0.0076 0.0629
Echinococcus granulosus histone acetyltransferase KAT2B 0.01 0.0266 0.0266
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0074 0.018 0.2969
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0074 0.0615
Schistosoma mansoni tyrosine kinase 0.0151 0.0434 0.0433
Mycobacterium ulcerans thiosulfate sulfurtransferase, CysA2 0.0028 0.0028 0.0042
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0229 0.0693 0.0693
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0166 0.0164
Onchocerca volvulus 0.0055 0.0118 0.0685
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.002 0.0124
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0097
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0033 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1292 0.4198 1
Plasmodium vivax JmjC domain containing protein 0.0045 0.0083 0.1528
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0023 0.0324
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0136 0.0383 0.0734
Schistosoma mansoni lozenge 0.0059 0.013 0.0128
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0054 0.0114 0.0972
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0136 0.0383 0.0383
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.0076 0.0373
Echinococcus granulosus chromobox protein 1 0.0071 0.0169 0.0169
Schistosoma mansoni hypothetical protein 0.0172 0.0502 0.05
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0097 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0262 0.0609
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.0026 0.0022 0.0022
Echinococcus granulosus Polycystic kidney disease protein 0.0106 0.0287 0.0287
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0028 0.0028 0.0043
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0026 0.0022 0.002
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0116 0.0317 0.0742
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0028 0.0051
Schistosoma mansoni lipoxygenase 0.0305 0.0941 0.094
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0083 0.0209 0.1836
Brugia malayi jmjC domain containing protein 0.0045 0.0083 0.041
Trichomonas vaginalis DNA polymerase eta, putative 0.0172 0.0505 0.1188
Mycobacterium ulcerans hypothetical protein 0.0027 0.0024 0.0035
Schistosoma mansoni hypothetical protein 0.0041 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.0153
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.005 0.0391
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0069 0.0069
Echinococcus granulosus histone acetyltransferase MYST2 0.0064 0.0146 0.0146
Trypanosoma brucei metacaspase 5, putative 0.0099 0.0262 0.2318
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0099 0.022
Onchocerca volvulus 0.011 0.03 0.1926
Plasmodium vivax rhodanese like protein, putative 0.0028 0.0028 0.0424
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.012 0.033 0.1754
Brugia malayi Hexokinase family protein 0.0081 0.0202 0.1052
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0028 0.0028 0.0192
Echinococcus granulosus expressed protein 0.0378 0.1184 0.1184
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0158 0.138
Leishmania major importin beta-1 subunit, putative 0.0024 0.0014 0.0066
Plasmodium falciparum thioredoxin reductase 0.0055 0.0116 0.2198
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0047 0.0096
Echinococcus multilocularis heat shock protein 67b2 0.0028 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.005 0.0099 0.0515
Mycobacterium ulcerans hypothetical protein 0.0187 0.0553 0.1028
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.0075 0.0075
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0032 0.0138
Schistosoma mansoni aldehyde dehydrogenase 0.0136 0.0383 0.0381
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0074 0.018 0.2969
Echinococcus multilocularis caspase 2 0.0222 0.0668 0.0668
Echinococcus multilocularis mitogen activated protein kinase 3 0.0115 0.0315 0.0315
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0041 0.0069 0.015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Loa Loa (eye worm) hypothetical protein 0.0058 0.0127 0.0661
Trypanosoma cruzi DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Brugia malayi nuclear receptor NHR-67 0.0026 0.0022 0.0082
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0074 0.0615
Echinococcus multilocularis dna polymerase eta 0.0112 0.0305 0.0305
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0258 0.2286
Trypanosoma cruzi As/Sb Reductase, putative 0.0028 0.0028 0.0192
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0074 0.0161
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0048 0.0095 0.1773
Entamoeba histolytica phosphoglycerate kinase, putative 0.0172 0.0505 0.1188
Mycobacterium tuberculosis Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic dehydrogenase) (fumarate reductase) (fumarate deh 0.0033 0.0043 0.0073
Schistosoma mansoni zinc finger protein 0.0026 0.0022 0.002
Entamoeba histolytica rodhanase-like domain containing protein 0.0028 0.0028 0.005
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0134 0.0687
Plasmodium falciparum mitogen-activated protein kinase phosphatase 1, putative 0.0028 0.0028 0.0424
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0172 0.0505 0.4526
Plasmodium falciparum rhodanese like protein, putative 0.0028 0.0028 0.0424
Leishmania major phosphoglycerate kinase B, cytosolic 0.0172 0.0505 0.4526
Trypanosoma brucei NADH dehydrogenase 0.0038 0.0063 0.0509
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0023 0.0038
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0172 0.0505 0.8539
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0071 0.0346
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0045 0.0083 0.1305
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0076 0.0166
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0076 0.0166
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0022 0.002
Onchocerca volvulus Huntingtin homolog 0.0124 0.0344 0.2228
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0055 0.0116 0.0215
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0055 0.0118 0.0117
Echinococcus multilocularis tumor protein p63 0.0755 0.2426 0.2426
Echinococcus granulosus ubiquitin specific protease 41 0.0049 0.0097 0.0097
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0132 0.0372 0.0689
Brugia malayi tailless protein 0.0026 0.0022 0.0082
Echinococcus granulosus caspase 8 0.0099 0.0262 0.0262
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) 0.0025 0.0018 0.0018
Onchocerca volvulus 0.0138 0.039 0.2538
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0028 0.005
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0064 0.0146 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0262 0.0609
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0047 0.0096
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0261 0.0798 0.0798
Trypanosoma brucei protein kinase, putative 0.0115 0.0315 0.2808
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0129
Loa Loa (eye worm) hypothetical protein 0.0029 0.0032 0.0152
Leishmania major eukaryotic translation initiation factor-like 0.0041 0.0069 0.0571
Mycobacterium ulcerans succinate dehydrogenase iron-sulfur subunit 0.0033 0.0043 0.0071
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0026 0.002 0.0046
Echinococcus multilocularis RUN 0.0106 0.0287 0.0287
Trypanosoma brucei hexokinase 0.0081 0.0202 0.1775
Schistosoma mansoni hypothetical protein 0.0133 0.0375 0.0374
Echinococcus granulosus phosphoglycerate kinase 1 0.0172 0.0505 0.0505
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.0258 0.0258
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0041 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0129
Entamoeba histolytica recQ family helicase, putative 0.0083 0.0209 0.0482
Loa Loa (eye worm) hypothetical protein 0.0055 0.0117 0.061
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseB 0.0028 0.0028 0.0043
Plasmodium falciparum metacaspase-like protein 0.0099 0.0262 0.5121
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.002 0.0124
Leishmania major hypothetical protein, conserved 0.0045 0.0083 0.0692
Echinococcus granulosus dna polymerase kappa 0.0172 0.0505 0.0505
Trichomonas vaginalis cdc25c, putative 0.0028 0.0028 0.005
Schistosoma mansoni nuclear hormone receptor 0.0055 0.0118 0.0117
Giardia lamblia DNA damage repair protein 0.0027 0.0024 0.0041
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0074 0.1359
Trichomonas vaginalis cdc25c, putative 0.0138 0.039 0.0914
Onchocerca volvulus 0.0098 0.0259 0.1643
Brugia malayi ImpB/MucB/SamB family protein 0.0112 0.0305 0.1606
Trypanosoma cruzi metacaspase, putative 0.0099 0.0262 0.2318
Loa Loa (eye worm) hypothetical protein 0.0074 0.018 0.0947
Echinococcus multilocularis dna polymerase kappa 0.0172 0.0505 0.0505
Trypanosoma brucei phosphoglycerate kinase 0.0172 0.0505 0.4526
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0631 0.2018 0.3767
Loa Loa (eye worm) hypothetical protein 0.0056 0.012 0.0626
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.002 0.0124
Trypanosoma brucei metacaspase MCA2 0.0099 0.0262 0.2318
Trichomonas vaginalis helicase, putative 0.0022 0.0009 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0047 0.0096
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0089
Echinococcus granulosus lipoxygenase domain containing protein 0.0106 0.0287 0.0287
Mycobacterium tuberculosis Conserved hypothetical protein 0.0086 0.022 0.0417
Loa Loa (eye worm) hypothetical protein 0.0083 0.021 0.1108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.002 0.0124
Giardia lamblia NADH oxidase lateral transfer candidate 0.0026 0.002 0.0032
Leishmania major hypothetical protein, conserved 0.0028 0.0028 0.0192
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0042 0.0076 0.1187
Trypanosoma brucei Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0025 0.0018 0.0103
Trypanosoma brucei trypanothione reductase 0.0055 0.0116 0.0995
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.005 0.0391
Entamoeba histolytica acetyltransferase, GNAT family 0.0087 0.0224 0.0518
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0074 0.1157
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0025 0.0018 0.0024
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0616
Trypanosoma brucei Metacaspase-4 0.0099 0.0262 0.2318
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.0022 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0118 0.0602
Echinococcus granulosus lysine specific demethylase 6a 0.0045 0.0083 0.0083
Trypanosoma cruzi mercaptopyruvate sulfurtransferase, putative 0.0028 0.0028 0.0192
Schistosoma mansoni cellular tumor antigen P53 0.011 0.03 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0005
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.002 0.0264
Brugia malayi jmjC domain containing protein 0.0228 0.0688 0.367
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0074 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.0172 0.0505 0.4526
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0071 0.129
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1292 0.4198 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0005
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0048 0.0095 0.049
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.01 0.0266 0.4446
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0048 0.0046
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.002 0.0273
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0071 0.0346
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0134 0.0687
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0074 0.0161
Brugia malayi mbt repeat family protein 0.0056 0.0121 0.0614
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0055 0.0118 0.0602
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0228 0.0688 0.0688
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.01 0.0852
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0022 0.0082
Schistosoma mansoni terminal deoxycytidyl transferase 0.0086 0.022 0.0218
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0023 0.0146

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.7079 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 89.1251 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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