Detailed information for compound 1442899

Basic information

Technical information
  • TDR Targets ID: 1442899
  • Name: 4-methoxy-N-[1-[2-[(4-methoxyphenyl)methylami no]-2-oxoethyl]piperidin-4-yl]benzamide
  • MW: 411.494 | Formula: C23H29N3O4
  • H donors: 2 H acceptors: 2 LogP: 2.57 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)CNC(=O)CN1CCC(CC1)NC(=O)c1ccc(cc1)OC
  • InChi: 1S/C23H29N3O4/c1-29-20-7-3-17(4-8-20)15-24-22(27)16-26-13-11-19(12-14-26)25-23(28)18-5-9-21(30-2)10-6-18/h3-10,19H,11-16H2,1-2H3,(H,24,27)(H,25,28)
  • InChiKey: AQQBEFGBQOQLND-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-methoxy-N-[1-[2-[(4-methoxyphenyl)methylamino]-2-oxo-ethyl]-4-piperidyl]benzamide
  • 4-methoxy-N-[1-[2-[(4-methoxyphenyl)methylamino]-2-oxoethyl]-4-piperidinyl]benzamide
  • N-[1-[2-keto-2-[(4-methoxybenzyl)amino]ethyl]-4-piperidyl]-4-methoxy-benzamide
  • 4-methoxy-N-[1-[2-[(4-methoxyphenyl)methylamino]-2-oxo-ethyl]piperidin-4-yl]benzamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0022
Onchocerca volvulus 0.0012 0.0026 0.01
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Echinococcus granulosus macrophage expressed protein 0.1368 0.7239 0.8393
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0026 0.011
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0016 0.0047 0.0047
Brugia malayi GnHR receptor homolog 0.0012 0.0026 0.0114
Schistosoma mansoni coup transcription factor 0.0016 0.0047 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0399 0.1447
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 0.0033 0.0137 0.2085
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0811 0.3676
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0135 0.0677 0.8837
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0026 0.0028
Echinococcus multilocularis somatostatin receptor 0.0012 0.0026 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0164 0.0557
Brugia malayi NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor 0.0033 0.0137 0.0638
Schistosoma mansoni cpg binding protein 0.003 0.0119 0.0136
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0016 0.0047 0.0049
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0042 0.0514
Trypanosoma brucei heat shock protein, putative 0.0018 0.0054 0.0791
Loa Loa (eye worm) hypothetical protein 0.0101 0.0497 0.2252
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.0126 0.0144
Schistosoma mansoni neuropeptide receptor 0.0012 0.0026 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0016 0.0047 0.0049
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0051 0.0232 0.3443
Echinococcus multilocularis geminin 0.0177 0.0905 0.1048
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0146 0.0657
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0276 0.0318
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0016 0.0047 0.0053
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0026 0.0028
Brugia malayi Cytochrome P450 family protein 0.0016 0.0047 0.0214
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0206 0.3057
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0244 0.11
Toxoplasma gondii patched family protein 0.0012 0.0023 0.0252
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0026 0.0114
Schistosoma mansoni hypothetical protein 0.0012 0.0026 0.0028
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0149 0.0171
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0149 0.2197
Mycobacterium leprae Probable lipase LipE 0.0035 0.0146 0.0354
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0083 0.0083
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0031 0.0415
Trypanosoma brucei unspecified product 0.002 0.0066 0.0974
Trypanosoma brucei heat shock protein, putative 0.0018 0.0054 0.0791
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0016 0.0047 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0016 0.0047 0.0208
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0058 0.0271 0.0743
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.019 0.2803
Loa Loa (eye worm) histone deacetylase 11 0.0014 0.0037 0.016
Plasmodium vivax histone deacetylase, putative 0.0048 0.0214 0.1497
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0394 0.0455
Loa Loa (eye worm) hypothetical protein 0.0046 0.0206 0.0931
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0232 0.0814
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0082 0.0084
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Brugia malayi hypothetical protein 0.007 0.0334 0.1564
Mycobacterium tuberculosis Possible oxidoreductase 0.0133 0.0668 0.0689
Echinococcus granulosus g protein coupled receptor 0.0012 0.0026 0.0028
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0016 0.0045 0.0045
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0505 0.2649 1
Mycobacterium ulcerans monoamine oxidase 0.0133 0.0668 0.0668
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0008 0.0004 0.0003
Echinococcus multilocularis expressed conserved protein 0.018 0.0919 0.1064
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0082 0.0377
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0146 0.0151
Onchocerca volvulus 0.0016 0.0045 0.0179
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0016 0.0047 0.0047
Onchocerca volvulus 0.0463 0.2423 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0026 0.0028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0026 0.0028
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0042 0.0047
Loa Loa (eye worm) hypothetical protein 0.0011 0.0021 0.0087
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0026 0.0028
Plasmodium vivax histone deacetylase 2, putative 0.0048 0.0214 0.1497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0026 0.0028
Schistosoma mansoni patched 1 0.0082 0.0399 0.046
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0051 0.0057
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0016 0.0045 0.0197
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0026 0.0028
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0146 0.0168
Schistosoma mansoni amine oxidase 0.0133 0.0668 0.0772
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0014 0.0037 0.0071
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Brugia malayi nuclear receptor RXR 0.0009 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Trypanosoma cruzi histone deacetylase, putative 0.0048 0.0214 0.3167
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0022
Echinococcus granulosus sex peptide receptor 0.0012 0.0026 0.0028
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.002 0.0087
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0026 0.011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0003 0.0002
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.019 0.019
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0042 0.0047
Brugia malayi TAR-binding protein 0.0062 0.0291 0.1364
Mycobacterium ulcerans recombinase A 0.0058 0.0271 0.0271
Echinococcus granulosus somatostatin receptor 0.0012 0.0026 0.0028
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0196 0.0917
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0267 0.0308
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0026 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0206 0.0965
Schistosoma mansoni amine GPCR 0.0012 0.0026 0.0028
Echinococcus multilocularis histone deacetylase 0.0048 0.0214 0.0246
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0026 0.0028
Trypanosoma cruzi histone deacetylase 1, putative 0.0014 0.0037 0.0503
Entamoeba histolytica hypothetical protein 0.0011 0.002 0.000000000022328
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0026 0.011
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0029 0.0113 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0095 0.0293
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0129 0.0645 0.3031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0291 0.1364
Schistosoma mansoni hypothetical protein 0.1368 0.7239 0.8393
Plasmodium falciparum perforin-like protein 3 0.0151 0.0765 0.5421
Mycobacterium leprae Conserved hypothetical protein 0.0016 0.0047 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0016 0.0047 0.0216
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0042 0.0186
Echinococcus multilocularis macrophage expressed protein 0.1368 0.7239 0.8393
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0035 0.0065
Loa Loa (eye worm) cytochrome P450 0.0016 0.0047 0.0207
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0018 0.0056 0.0823
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0026 0.0028
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0016 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.016
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0016 0.0047 0.0189
Trichomonas vaginalis chromobox protein, putative 0.0011 0.002 0.0008
Onchocerca volvulus Protein ultraspiracle homolog 0.0016 0.0047 0.0189
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0084
Echinococcus granulosus Niemann Pick C1 protein 0.0274 0.1419 0.1644
Plasmodium vivax hypothetical protein, conserved 0.0011 0.002 0.012
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0026 0.0028
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0014 0.0035 0.0422
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0082 0.1177
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.002 0.0022
Onchocerca volvulus Phospholipase A2 homolog 0.0421 0.2202 0.9087
Echinococcus multilocularis histone deacetylase 8 0.0014 0.0037 0.0041
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0026 0.0028
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0082 0.0234
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0008 0.007
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0171 0.2607
Brugia malayi Serotonin receptor 0.0012 0.0026 0.0114
Plasmodium vivax acetyl-CoA synthetase, putative 0.0014 0.0033 0.021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0657
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0016 0.0047 0.0053
Loa Loa (eye worm) histone deacetylase 3 0.0014 0.0037 0.016
Echinococcus multilocularis Chromo domain 0.0011 0.002 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Entamoeba histolytica hypothetical protein 0.007 0.0334 0.1192
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.0008
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0129 0.0645 0.0746
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0208
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0208
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0645 1
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0037 0.0071
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.002 0.000000000022328
Leishmania major UDP-galactopyranose mutase 0.0133 0.0668 1
Echinococcus granulosus histone deacetylase 6 0.0048 0.0214 0.0246
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0206 0.0965
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0085 0.1269
Echinococcus multilocularis heat shock protein 90 0.0018 0.0054 0.0061
Schistosoma mansoni neuropeptide receptor 0.0012 0.0026 0.0028
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0195 0.0997 0.1154
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0032 0.0132 0.0136
Echinococcus granulosus chromobox protein 1 0.0068 0.0324 0.0374
Echinococcus granulosus chromobox protein 1 0.0068 0.0324 0.0374
Plasmodium falciparum ataxin-2 like protein, putative 0.0013 0.0029 0.0181
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.019 0.2902
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.002 0.0221
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0016 0.0047 0.0049
Trypanosoma brucei heat shock protein, putative 0.0018 0.0054 0.0791
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0033 0.046
Schistosoma mansoni lipoxygenase 0.1628 0.8625 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0026 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0016 0.0047 0.0049
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0146 0.0168
Brugia malayi Patched protein homolog 1 0.0012 0.0023 0.0099
Loa Loa (eye worm) hypothetical protein 0.0015 0.0042 0.0186
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0033 0.0137 0.2013
Plasmodium vivax multidomain scavenger receptor, putative 0.0272 0.1409 1
Brugia malayi beta-lactamase family protein 0.0035 0.0146 0.0681
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0033 0.046
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0083 0.1041
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0003 0.0002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0042 0.0589
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0031 0.0049
Schistosoma mansoni terminal deoxycytidyl transferase 0.0029 0.0113 0.0129
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, putative 0.0033 0.0137 0.2085
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0014 0.0035 0.0501
Echinococcus granulosus histone deacetylase 3 0.0014 0.0037 0.0041
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0033 0.0057
Schistosoma mansoni polycystin 1-related 0.0272 0.1409 0.1632
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0037 0.0071
Echinococcus multilocularis dna polymerase eta 0.0042 0.0186 0.0214
Schistosoma mansoni SET domain protein 0.001 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0038 0.0078
Loa Loa (eye worm) patched family protein 0.0012 0.0023 0.0095
Brugia malayi putative neuropeptide receptor 0.0012 0.0026 0.0114
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0008 0.0003 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0196 0.0226
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0083 0.0085
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0303 0.1574 0.1824
Giardia lamblia Grp94/Hsp90 0.0014 0.0035 0.0102
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0033 0.0444
Echinococcus granulosus cpg binding protein 0.003 0.0119 0.0136
Onchocerca volvulus 0.0028 0.011 0.045
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0324 0.1466
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0016 0.0047 0.0208
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Mycobacterium ulcerans lipase LipD 0.0035 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0082 0.0399 0.1804
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1628 0.8625 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0033 0.0034
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0206 0.0709
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0026 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0033 0.0147
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0206 0.0206
Echinococcus granulosus FTZ F1 alpha 0.0016 0.0047 0.0053
Trypanosoma brucei heat shock protein, putative 0.0018 0.0054 0.0791
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0031 0.0415
Onchocerca volvulus 0.0081 0.0394 0.1622
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0026 0.0028
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0016 0.0047 0.0047
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0047 0.0053
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0084
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0026 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0026 0.0028
Schistosoma mansoni SET domain protein 0.0019 0.0064 0.0072
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0033 0.0387
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0206 0.0213
Loa Loa (eye worm) hypothetical protein 0.003 0.012 0.054
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0505 0.2649 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0026 0.01
Plasmodium vivax patched family protein, putative 0.0012 0.0023 0.0137
Brugia malayi hypothetical protein 0.0272 0.1409 0.6631
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0259 0.3353
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0026 0.01
Trichomonas vaginalis chromobox protein, putative 0.0041 0.018 0.0615
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0149 0.0499
Onchocerca volvulus Serine\/threonine kinase homolog 0.0051 0.0232 0.0952
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0208
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0026 0.0028
Leishmania major histone deacetylase, putative 0.0014 0.0037 0.0503
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0206 0.0206
Brugia malayi Nuclear hormone receptor-like 1 0.0009 0.0007 0.0023
Loa Loa (eye worm) histone deacetylase 7A 0.0048 0.0214 0.0964
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0026 0.0028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.002 0.0008
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0146 0.0146
Plasmodium vivax hypothetical protein, conserved 0.0011 0.002 0.012
Echinococcus granulosus geminin 0.0177 0.0905 0.1048
Leishmania major DNA polymerase eta, putative 0.0023 0.0081 0.1172
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0247 0.1274 0.3877
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0042 0.0047
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0026 0.0028
Trypanosoma brucei glucosidase, putative 0.0035 0.0149 0.2274
Brugia malayi Protein kinase domain containing protein 0.0031 0.0127 0.0589
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0016 0.0047 0.0049
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.002 0.0022
Trichomonas vaginalis set domain proteins, putative 0.0463 0.2422 0.9139
Loa Loa (eye worm) heat shock protein 90 0.0018 0.0054 0.0238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0016 0.0047 0.0208
Trypanosoma brucei heat shock protein, putative 0.0018 0.0054 0.0791
Entamoeba histolytica serine/threonine protein kinase, putative 0.0051 0.0232 0.0806
Plasmodium falciparum perforin-like protein 5 0.0151 0.0765 0.5421
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0079 0.0383 0.0442
Loa Loa (eye worm) isocitrate dehydrogenase 0.0008 0.0003 0.0008
Toxoplasma gondii perforin-like protein PLP1 0.0151 0.0765 1
Brugia malayi hypothetical protein 0.0133 0.0668 0.3138
Toxoplasma gondii histone deacetylase HDAC5 0.0014 0.0037 0.0447
Loa Loa (eye worm) hypothetical protein 0.0046 0.0206 0.0931
Plasmodium vivax DNA repair protein REV1, putative 0.0009 0.0008 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0505 0.2649 1
Echinococcus granulosus g protein coupled receptor 0.0012 0.0026 0.0028
Schistosoma mansoni chromobox protein 0.0011 0.002 0.0022
Giardia lamblia Fructose-bisphosphate aldolase 0.0505 0.2649 1
Echinococcus granulosus flap endonuclease 1 0.0014 0.0035 0.0039
Onchocerca volvulus 0.0272 0.1409 0.5813
Trypanosoma cruzi histone deacetylase, putative 0.0014 0.0037 0.0503
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0019 0.0064 0.0072
Brugia malayi ORL1-like opioid receptor 0.0012 0.0026 0.0114
Leishmania major hypothetical protein, conserved 0.0015 0.0042 0.0589
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0026 0.011
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0208
Brugia malayi hypothetical protein 0.0012 0.0023 0.0099
Echinococcus granulosus RUN 0.0272 0.1409 0.1632
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0047 0.0659
Entamoeba histolytica hypothetical protein 0.0023 0.0083 0.0238
Schistosoma mansoni rab6-interacting 0.0272 0.1409 0.1632
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Toxoplasma gondii histone deacetylase HDAC2 0.0014 0.0037 0.0439
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0033 0.0444
Onchocerca volvulus 0.0012 0.0026 0.01
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0016 0.0047 0.0216
Brugia malayi Cytochrome P450 family protein 0.0024 0.0086 0.04
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.0033 0.0137 0.0453
Schistosoma mansoni alpha-glucosidase 0.0137 0.0692 0.0801
Schistosoma mansoni hypothetical protein 0.0079 0.0383 0.0442
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0016 0.0047 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0132 0.2007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0567
Echinococcus multilocularis protein dispatched 1 0.0094 0.0461 0.0532
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0033 0.0142
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0016 0.0045 0.0046
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0016 0.0047 0.0053
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0097 0.0479 0.1973
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Echinococcus multilocularis flap endonuclease 1 0.0014 0.0035 0.0039
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0209 0.1071 1
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0026 0.0028
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0014 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0105 0.0331
Schistosoma mansoni neuropeptide receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0649
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.0126 0.0144
Echinococcus multilocularis histone deacetylase 1 0.0014 0.0037 0.0041
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0014 0.0035 0.0477
Echinococcus granulosus expressed conserved protein 0.018 0.0919 0.1064
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0042 0.061
Plasmodium vivax hypothetical protein, conserved 0.0133 0.0668 0.4726
Trypanosoma cruzi Heat shock protein 83, putative 0.0018 0.0054 0.0764
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.019 0.2902
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0031 0.0049
Schistosoma mansoni histone deacetylase hda2 0.0014 0.0037 0.0041
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0196 0.0226
Echinococcus granulosus Polycystic kidney disease protein 0.0272 0.1409 0.1632
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0042 0.0514
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0206 0.0206
Leishmania major hypothetical protein, conserved 0.0035 0.0146 0.2149
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0033 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0054 0.0137
Onchocerca volvulus 0.0035 0.0146 0.0597
Onchocerca volvulus 0.0046 0.0206 0.0846
Onchocerca volvulus 0.0012 0.0026 0.01
Loa Loa (eye worm) hypothetical protein 0.0082 0.0399 0.1804
Onchocerca volvulus 0.0035 0.0146 0.0597
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0014 0.0033 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0232 0.0814
Loa Loa (eye worm) flap endonuclease-1 0.0014 0.0035 0.0154
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0033 0.021
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0026 0.0028
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0146 0.0487
Toxoplasma gondii histone deacetylase HDAC1 0.0048 0.0214 0.2761
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0247 0.1274 0.1274
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0144 0.1003
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0033 0.0034
Brugia malayi Myosin head containing protein 0.0012 0.0023 0.0099
Trypanosoma cruzi UDP-galactopyranose mutase 0.0133 0.0668 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0026 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Schistosoma mansoni opsin-like receptor 0.0012 0.0026 0.0028
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0026 0.0028
Echinococcus multilocularis endoplasmin 0.0014 0.0035 0.0039
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0026 0.0028
Brugia malayi Histone deacetylase 1 0.0014 0.0037 0.0166
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0105 0.0331
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0033 0.0048
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0029 0.0031
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0026 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0149 0.2197
Onchocerca volvulus 0.0012 0.0026 0.01
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.002 0.000000000022328
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0081 0.1172
Onchocerca volvulus 0.0012 0.0026 0.01
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0026 0.0028
Brugia malayi RNA binding protein 0.0062 0.0291 0.1364
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0291 0.0336
Schistosoma mansoni amine GPCR 0.0012 0.0026 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0026 0.0028
Trypanosoma brucei histone deacetylase, putative 0.0048 0.0214 0.328
Loa Loa (eye worm) helicase 0.0011 0.002 0.0084
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0649
Loa Loa (eye worm) histone deacetylase 1 0.0014 0.0037 0.016
Onchocerca volvulus 0.0012 0.0026 0.01
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0026 0.0028
Echinococcus multilocularis 0.0133 0.0668 0.0772
Toxoplasma gondii patched family protein 0.0012 0.0023 0.0252
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0012 0.0026 0.011
Echinococcus granulosus chromobox protein 2 0.0011 0.002 0.0022
Echinococcus granulosus phd:f box containing protein 0.0015 0.0042 0.0047
Brugia malayi nuclear hormone receptor 0.0016 0.0047 0.0216
Plasmodium falciparum DNA repair protein REV1, putative 0.0009 0.0008 0.0033
Echinococcus granulosus death domain containing protein 0.0031 0.0126 0.0144
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0146 0.0151
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.1194 0.1383
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0026 0.0028
Echinococcus granulosus g protein coupled receptor 0.0012 0.0026 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0054 0.0137
Plasmodium vivax histone deacetylase 1, putative 0.0014 0.0037 0.0238
Giardia lamblia Flap structure-specific endonuclease 0.0014 0.0035 0.0104
Loa Loa (eye worm) RNA binding protein 0.0062 0.0291 0.1316
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.019 0.0652
Brugia malayi SWIRM domain containing protein 0.0133 0.0668 0.3138
Brugia malayi Steroid receptor seven-up type 2 0.0016 0.0047 0.0216
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0026 0.0028
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0026 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.0008
Echinococcus multilocularis neuropeptide receptor A26 0.0012 0.0026 0.0028
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0645 0.9658
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.019 0.2902
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0084
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0016 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0293 0.0338
Onchocerca volvulus 0.003 0.012 0.0491
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0033 0.0034
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0016 0.0047 0.0053
Echinococcus granulosus fmrfamide receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0126 0.0564
Brugia malayi serine/threonine-protein kinase plk-2 0.0051 0.0232 0.1086
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0033 0.0387
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0016 0.0047 0.0053
Toxoplasma gondii exonuclease III APE 0.0023 0.0082 0.1026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0009 0.0007 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0196 0.0226
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0276 0.0319
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0026 0.0028
Echinococcus multilocularis protoporphyrinogen oxidase 0.0133 0.0668 0.0772
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0016 0.0047 0.0216
Brugia malayi hypothetical protein 0.0232 0.1194 0.5618
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0026 0.0028
Mycobacterium ulcerans hypothetical protein 0.0035 0.0146 0.0146
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0192 0.0981 0.3656
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0206 0.3057
Echinococcus granulosus neuropeptide receptor A26 0.0012 0.0026 0.0028
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Schistosoma mansoni amine GPCR 0.0012 0.0026 0.0028
Schistosoma mansoni steroid hormone receptor ad4bp 0.0016 0.0047 0.0053
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0027 0.031
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0291 0.0336
Echinococcus multilocularis histone deacetylase 6 0.0048 0.0214 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.0008
Echinococcus multilocularis RUN 0.0272 0.1409 0.1632
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0026 0.0028
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Plasmodium vivax flap endonuclease 1, putative 0.0014 0.0035 0.0229
Leishmania major histone deacetylase, putative 0.0014 0.0037 0.0503
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0276 0.0318
Schistosoma mansoni biogenic amine receptor 0.0012 0.0026 0.0028
Schistosoma mansoni cytochrome P450 0.0016 0.0047 0.0053
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0012 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.019 0.2803
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0016 0.0047 0.0053
Onchocerca volvulus 0.0012 0.0026 0.01
Loa Loa (eye worm) hypothetical protein 0.0013 0.0029 0.0123
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0016 0.0047 0.0053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0505 0.2649 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.0047 0.0053
Loa Loa (eye worm) patched family protein 0.0012 0.0023 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0054 0.0137
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0146 0.0168
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0047 0.0216
Trypanosoma cruzi UDP-galactopyranose mutase 0.0133 0.0668 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0149 0.0671
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0196 0.0226
Schistosoma mansoni histone deacetylase hda2 0.0048 0.0214 0.0246
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0016 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.007 0.0334 0.1192
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0026 0.0028
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0033 0.0444
Trypanosoma cruzi heat shock protein 90, putative 0.001 0.0016 0.0188
Echinococcus multilocularis 0.0016 0.0047 0.0053
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0033 0.0036
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0033 0.0036
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0026 0.011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0134 0.0138
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0026 0.0028
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Loa Loa (eye worm) oxidoreductase 0.0014 0.0033 0.0142
Schistosoma mansoni chromobox protein 0.0068 0.0324 0.0374
Onchocerca volvulus 0.0272 0.1409 0.5813
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0016 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Mycobacterium ulcerans dehydrogenase 0.0133 0.0668 0.0668
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.019 0.2902
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0026 0.0028
Plasmodium falciparum perforin-like protein 1 0.0151 0.0765 0.5421
Trichomonas vaginalis CAMK family protein kinase 0.0025 0.0095 0.0293
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0146 0.2149
Brugia malayi Isocitrate dehydrogenase 0.0008 0.0003 0.0008
Mycobacterium tuberculosis Conserved protein 0.0035 0.0146 0.0151
Brugia malayi hypothetical protein 0.0011 0.0021 0.009
Echinococcus granulosus sterol regulatory element binding protein 0.0082 0.0399 0.046
Schistosoma mansoni chromobox protein 0.0011 0.002 0.0022
Plasmodium falciparum heat shock protein 90 0.0018 0.0054 0.0361
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0033 0.0033
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0026 0.0028
Schistosoma mansoni opsin-like receptor 0.0012 0.0026 0.0028
Brugia malayi Niemann-Pick C1 protein precursor 0.0192 0.0981 0.4615
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0082 0.1219
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0016 0.0045 0.0046
Trypanosoma brucei DNA polymerase eta, putative 0.0042 0.0186 0.2852
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0031 0.0049
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Echinococcus multilocularis isocitrate dehydrogenase 0.0008 0.0003 0.0002
Schistosoma mansoni ap endonuclease 0.0023 0.0082 0.0093
Loa Loa (eye worm) beta-lactamase 0.0035 0.0146 0.0657
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.019 0.0652
Giardia lamblia DINP protein human, muc B family 0.0032 0.0132 0.047
Brugia malayi Heterochromatin protein 1 0.0068 0.0324 0.1519
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0008 0.0004 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0134 0.0138
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.002 0.012
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0649
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0133 0.0668 0.0772
Onchocerca volvulus 0.0092 0.0452 0.1861
Mycobacterium ulcerans NADH dehydrogenase I subunit F 0.0033 0.0137 0.0137
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0026 0.0028
Echinococcus multilocularis ecdysone induced protein 78C 0.0016 0.0047 0.0053
Echinococcus multilocularis serotonin receptor 0.0012 0.0026 0.0028
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0149 0.0499
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Plasmodium vivax hypothetical protein, conserved 0.0133 0.0668 0.4726
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0016 0.0047 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0232 0.0267
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Brugia malayi photoreceptor-specific nuclear receptor 0.0016 0.0047 0.0216
Chlamydia trachomatis recombinase RecA 0.0058 0.0271 0.1903
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Leishmania major cytochrome p450-like protein 0.0016 0.0047 0.0659
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0029 0.0113 0.0129
Echinococcus granulosus tar DNA binding protein 0.0062 0.0291 0.0336
Echinococcus multilocularis Chromobox protein 3 0.0011 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Trypanosoma cruzi DNA repair protein, putative 0.0018 0.0056 0.0794
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0054 0.0137
Brugia malayi amine oxidase, flavin-containing family protein 0.0133 0.0668 0.3138
Brugia malayi polk-prov protein 0.0023 0.0084 0.039
Plasmodium falciparum histone deacetylase, putative 0.0048 0.0214 0.1497
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0146 0.1015
Onchocerca volvulus 0.0012 0.0023 0.0087
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0657
Schistosoma mansoni biogenic amine receptor 0.0012 0.0026 0.0028
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0334 0.0385
Plasmodium falciparum flap endonuclease 1 0.0014 0.0035 0.0229
Echinococcus granulosus nuclear factor of activated T cells 5 0.0303 0.1574 0.1824
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0026 0.0028
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0016 0.0047 0.0047
Brugia malayi SET domain containing protein 0.0014 0.0038 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0085 0.1269
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Schistosoma mansoni histone deacetylase 0.0014 0.0037 0.0041
Schistosoma mansoni flap endonuclease-1 0.0013 0.0028 0.0031
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0149 0.0499
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.002 0.0221
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0014 0.0035 0.0484
Echinococcus granulosus hypothetical protein 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0026 0.0028
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0149 0.0499
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0026 0.0028
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0016 0.0047 0.0047
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0146 0.0146
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0026 0.0028
Brugia malayi beta-lactamase 0.0035 0.0146 0.0681
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.002 0.000000000022328
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0033 0.0034
Brugia malayi neuropeptide F receptor 0.0012 0.0026 0.0114
Brugia malayi protein C24B5.3 0.0012 0.0023 0.0099
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Echinococcus granulosus dna polymerase eta 0.0042 0.0186 0.0214
Mycobacterium ulcerans oxidoreductase 0.0133 0.0668 0.0668
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1679 0.8896 0.9175
Echinococcus multilocularis histone deacetylase 6 0.0048 0.0214 0.0246
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0026 0.0028
Schistosoma mansoni rab6-interacting 0.0272 0.1409 0.1632
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0146 0.0354
Brugia malayi hypothetical protein 0.0012 0.0023 0.0099
Onchocerca volvulus 0.0047 0.0212 0.087
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0657
Schistosoma mansoni cpg binding protein 0.003 0.0119 0.0136
Echinococcus granulosus lysine specific histone demethylase 1A 0.0133 0.0668 0.0772
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0016 0.0047 0.0047
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0026 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.007 0.0336 0.0388
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0811 0.3811
Schistosoma mansoni cpg binding protein 0.0028 0.011 0.0126
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0026 0.0028
Schistosoma mansoni amine GPCR 0.0012 0.0026 0.0028
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0026 0.0028
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0058 0.0271 0.2275
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0016 0.0047 0.0047
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0021 0.009
Schistosoma mansoni RAR-like nuclear receptor 0.0016 0.0047 0.0053
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0083 0.046
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0394 0.0455
Schistosoma mansoni hypothetical protein 0.0011 0.002 0.0022
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0083 0.1236
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0033 0.0387
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0016 0.0045 0.0046
Echinococcus granulosus serotonin receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) patched family protein 0.0012 0.0023 0.0095
Echinococcus multilocularis histone deacetylase 7 0.0048 0.0214 0.0246
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0033 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0054 0.0137
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0083 0.0083
Loa Loa (eye worm) histone deacetylase 0.0048 0.0214 0.0964
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0144 0.0149
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0033 0.0444
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0196 0.0226
Trypanosoma cruzi PAB1-binding protein , putative 0.0013 0.0029 0.0382
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.019 0.2902
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0026 0.0028
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0033 0.0033
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0033 0.0444
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0016 0.0047 0.0049
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0012 0.0023 0.0024
Loa Loa (eye worm) hypothetical protein 0.0013 0.0031 0.0133
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0026 0.0028
Mycobacterium ulcerans heat shock protein 90 0.0014 0.0035 0.0035
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0186 0.087
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Brugia malayi CHE-14 protein 0.0082 0.0399 0.187
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.1194 0.1383
Onchocerca volvulus 0.0012 0.0023 0.0087
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0086 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0084 0.1263
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0206 0.0206
Echinococcus granulosus neuropeptide s receptor 0.0012 0.0026 0.0028
Trypanosoma brucei heat shock protein, putative 0.0018 0.0054 0.0791
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0291 0.0336
Schistosoma mansoni hypothetical protein 0.0012 0.0026 0.0028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0134 0.0138
Entamoeba histolytica heat shock protein 90, putative 0.0018 0.0054 0.0129
Onchocerca volvulus 0.0012 0.0023 0.0087
Brugia malayi Flap endonuclease-1 0.0014 0.0035 0.016
Onchocerca volvulus 0.0016 0.0045 0.0179
Echinococcus granulosus histone deacetylase 6 0.0048 0.0214 0.0246
Schistosoma mansoni myosin xvIII 0.0012 0.0026 0.0028
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0016 0.0047 0.0682
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0016 0.0047 0.0047
Loa Loa (eye worm) twinkle helicase 0.006 0.0278 0.1256
Loa Loa (eye worm) hypothetical protein 0.0046 0.0206 0.0931
Loa Loa (eye worm) hypothetical protein 0.0059 0.0276 0.1249
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0026 0.0028
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Echinococcus granulosus Niemann Pick C1 protein 0.0192 0.0981 0.1136
Brugia malayi jmjC domain containing protein 0.0015 0.0042 0.0193
Echinococcus granulosus ecdysone induced protein 78C 0.0016 0.0047 0.0053
Brugia malayi Melatonin receptor type 1A 0.0012 0.0026 0.0114
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0657
Brugia malayi hypothetical protein 0.0009 0.0007 0.0023
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0031 0.0415
Schistosoma mansoni DNA polymerase eta 0.0042 0.0186 0.0214
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0035 0.0065
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0016 0.0047 0.0049
Leishmania major histone deacetylase, putative 0.0048 0.0214 0.3167
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0133 0.0668 0.4726
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0008 0.007
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0016 0.0047 0.0216
Echinococcus multilocularis thyroid hormone receptor alpha 0.0016 0.0047 0.0053
Plasmodium vivax ataxin-2 like protein, putative 0.0013 0.0029 0.0181
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0149 0.0171
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.019 0.2803
Echinococcus granulosus neuropeptide receptor 0.0012 0.0026 0.0028
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0026 0.0028
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0042 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0164 0.0557
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Echinococcus multilocularis sex peptide receptor 0.0012 0.0026 0.0028
Leishmania major cytochrome p450-like protein 0.0024 0.0086 0.1251
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0016 0.0047 0.0053
Trichomonas vaginalis flap endonuclease-1, putative 0.0014 0.0035 0.0067
Echinococcus granulosus lipoxygenase domain containing protein 0.0272 0.1409 0.1632
Brugia malayi follicle stimulating hormone receptor 0.0012 0.0026 0.0114
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Onchocerca volvulus 0.0012 0.0026 0.01
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0209 0.1071 0.3243
Schistosoma mansoni opsin-like receptor 0.0012 0.0026 0.0028
Brugia malayi Patched related family protein 10 0.0012 0.0023 0.0099
Onchocerca volvulus 0.0012 0.0026 0.01
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0082 0.1177
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.019 0.2902
Trichomonas vaginalis chromobox protein, putative 0.0011 0.002 0.0008
Toxoplasma gondii patched family protein 0.0012 0.0023 0.0252
Brugia malayi jmjC domain containing protein 0.0059 0.0276 0.1293
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0126 0.0585
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.019 0.2803
Schistosoma mansoni thyroid hormone receptor 0.0016 0.0047 0.0053
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0008 0.0003 0.0002
Trypanosoma cruzi DNA repair protein, putative 0.0018 0.0056 0.0794
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0033 0.0034
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0022
Echinococcus multilocularis FTZ F1 alpha 0.0016 0.0047 0.0053
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0054 0.0137
Echinococcus multilocularis protein patched 0.0082 0.0399 0.046
Schistosoma mansoni alpha glucosidase 0.0035 0.0149 0.0171
Schistosoma mansoni hypothetical protein 0.0012 0.0026 0.0028
Trypanosoma brucei heat shock protein 90, putative 0.0018 0.0054 0.0791
Brugia malayi Cytochrome P450 family protein 0.0053 0.0244 0.114
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0086 0.1251
Trypanosoma brucei heat shock protein 90, putative 0.0018 0.0054 0.0791
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0811 0.0938
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0212 0.0993
Plasmodium vivax perforin-like protein 5 0.0151 0.0765 0.5421
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0003 0.0002
Leishmania major histone deacetylase, putative 0.0048 0.0214 0.3167
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Plasmodium vivax heat shock protein 86, putative 0.0018 0.0054 0.0361
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0016 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0016 0.0047 0.0049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0134 0.0138
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.0186 0.2754
Onchocerca volvulus 0.0012 0.0023 0.0087
Trypanosoma brucei unspecified product 0.0039 0.0171 0.2607
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0082 0.0278
Schistosoma mansoni alpha-glucosidase 0.0137 0.0692 0.0801
Schistosoma mansoni lipoxygenase 0.1138 0.6018 0.6977
Brugia malayi hypothetical protein 0.0013 0.0029 0.0128
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0047 0.0053
Schistosoma mansoni histone deacetylase 4 5 0.0048 0.0214 0.0246
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0133 0.0668 0.4726
Trypanosoma cruzi histone deacetylase, putative 0.0014 0.0037 0.0503
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0164 0.0672
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.1145 0.1181
Echinococcus multilocularis neuropeptide s receptor 0.0012 0.0026 0.0028
Brugia malayi neuropeptide F receptor 0.0012 0.0026 0.0114
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0129 0.0645 0.0746
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0016 0.0047 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0505 0.2649 1
Plasmodium falciparum heterochromatin protein 1 0.0011 0.002 0.012
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0247 0.1274 0.1314
Loa Loa (eye worm) hypothetical protein 0.0192 0.0981 0.4452
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0206 0.0206
Echinococcus granulosus lysine specific histone demethylase 1A 0.0133 0.0668 0.0772
Trypanosoma brucei hypothetical protein, conserved 0.0009 0.0008 0.0073
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Echinococcus granulosus dna polymerase kappa 0.0043 0.019 0.0218
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0505 0.2649 1
Trypanosoma cruzi histone deacetylase 1, putative 0.0014 0.0037 0.0503
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0026 0.0028
Onchocerca volvulus 0.0012 0.0023 0.0087
Schistosoma mansoni hypothetical protein 0.0047 0.0212 0.0244
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0206 0.0206
Trypanosoma cruzi PAB1-binding protein , putative 0.0013 0.0029 0.0382
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.019 0.2902
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0129 0.0645 0.9658
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0009 0.0007 0.0006
Mycobacterium ulcerans hypothetical protein 0.0009 0.0008 0.0008
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0016 0.0045 0.0046
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0026 0.011
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0129 0.0645 0.0746
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0042 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.0008
Trypanosoma brucei PAB1-binding protein , putative 0.0013 0.0029 0.0396
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0276 0.0319
Mycobacterium leprae putative cytochrome p450 0.0016 0.0047 0.0045
Leishmania major DNA polymerase kappa, putative 0.0032 0.0132 0.1938
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0016 0.0047 0.0049
Mycobacterium tuberculosis Conserved hypothetical protein 0.0029 0.0113 0.0117
Trichomonas vaginalis chromobox protein, putative 0.0011 0.002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0133 0.0668 0.3027
Echinococcus granulosus lysine specific demethylase 5A 0.0059 0.0276 0.0318
Plasmodium falciparum perforin-like protein 4 0.0151 0.0765 0.5421
Schistosoma mansoni microtubule-associated protein tau 0.1344 0.7114 0.8248
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0026 0.0028
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0082 0.0556
Loa Loa (eye worm) steroid hormone receptor 0.0016 0.0047 0.0208
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0014 0.0035 0.0039
Schistosoma mansoni histone deacetylase 0.0014 0.0037 0.0041
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0505 0.2649 1
Mycobacterium ulcerans acetyl-CoA synthetase 0.0014 0.0033 0.0033
Echinococcus granulosus neuropeptide receptor 0.0012 0.0026 0.0028
Brugia malayi AKH receptor 0.0012 0.0026 0.0114
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0082 0.0556
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0014 0.0033 0.0033
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0324 0.1164
Trichomonas vaginalis chromobox protein, putative 0.0041 0.018 0.0615
Trypanosoma brucei polo-like protein kinase 0.0051 0.0232 0.3565
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0021 0.0023
Chlamydia trachomatis replicative DNA helicase 0.0209 0.1071 1
Giardia lamblia Kinase, PLK 0.0051 0.0232 0.0848
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0014 0.0037 0.0071
Echinococcus granulosus heat shock protein 90 0.0018 0.0054 0.0061
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0086 0.0386
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0014 0.0035 0.0007
Onchocerca volvulus 0.0012 0.0026 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Schistosoma mansoni hypothetical protein 0.0272 0.1409 0.1632
Brugia malayi Cytochrome P450 family protein 0.0024 0.0086 0.04
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0029 0.0031
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0033 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0016 0.0047 0.0208
Echinococcus multilocularis heat shock protein 90 0.0014 0.0035 0.0039
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0038 0.0078
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0146 0.2225
Onchocerca volvulus 0.0012 0.0026 0.01
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0083 0.1194
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0031 0.0049
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0047 0.0053
Onchocerca volvulus 0.0012 0.0023 0.0087
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.084
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1886 1 1
Plasmodium vivax histone deacetylase, putative 0.0014 0.0037 0.0238
Trichomonas vaginalis hypothetical protein 0.0011 0.002 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0232 0.0814
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0086 0.0386
Brugia malayi Patched related family protein 4 0.0012 0.0023 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0016 0.0047 0.0216
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0083 0.0156
Leishmania major DNA damage repair protein, putative 0.0009 0.0008 0.007
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0149 0.0499
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0394 0.0455
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0267 0.0308
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0657
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0276 0.0319
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0085 0.1269
Trypanosoma brucei chrX additional, unordered contigs 0.0009 0.0008 0.0073
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0146 0.0151
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.002 0.0221
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0146 0.0151
Schistosoma mansoni netrin receptor unc5 0.0031 0.0126 0.0144
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0083 0.1041
Loa Loa (eye worm) hypothetical protein 0.0015 0.0042 0.0186
Plasmodium falciparum LCCL domain-containing protein 0.0272 0.1409 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0133 0.0668 0.0689
Brugia malayi G-protein coupled receptor 0.0012 0.0026 0.0114
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0149 0.2197
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.0033 0.0137 0.0157
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0033 0.0033
Treponema pallidum recombinase A 0.0058 0.0271 0.1022
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Brugia malayi Histone deacetylase family protein 0.0048 0.0214 0.1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0009 0.0008 0.0073
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0259 0.0298
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0206 0.0542
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0042 0.0047
Trypanosoma cruzi heat shock protein 85, putative 0.0018 0.0054 0.0764
Brugia malayi Uncoordinated protein 44 0.0031 0.0126 0.0585
Entamoeba histolytica deoxycytidyl transferase, putative 0.0029 0.0113 0.0354
Loa Loa (eye worm) endoplasmin 0.0018 0.0054 0.0238
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0033 0.0036
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0031 0.0049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0126 0.0564
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0133 0.0668 0.0772
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.002 0.0087
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0016 0.0045 0.0038
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.0126 0.0144
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0016 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Echinococcus granulosus arachidonate 5 lipoxygenase 0.1628 0.8625 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0084
Echinococcus multilocularis chromobox protein 1 0.0068 0.0324 0.0374
Plasmodium vivax perforin-like protein 4 0.0151 0.0765 0.5421
Giardia lamblia Heat shock protein HSP 90-alpha 0.0018 0.0054 0.0174
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0394 0.185
Treponema pallidum replicative DNA helicase (dnaB) 0.0209 0.1071 0.4043
Chlamydia trachomatis protoporphyrinogen oxidase 0.0133 0.0668 0.592
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0232 0.0814
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0082 0.0093
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0031 0.0138
Brugia malayi Patched related family protein 12 0.0012 0.0023 0.0099
Schistosoma mansoni hypothetical protein 0.0031 0.0126 0.0144
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.0126 0.0144
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.019 0.019
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0016 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0022
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0026 0.011
Brugia malayi histone deacetylase 1 (HD1) 0.0014 0.0037 0.0166
Loa Loa (eye worm) hypothetical protein 0.0421 0.2202 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0267 0.0308
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0291 0.1316
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.0033 0.0137 0.0453
Echinococcus multilocularis NADH dehydrogenase (ubiquinone) flavoprotein 1 0.0033 0.0137 0.0157
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0009 0.0007 0.0006
Giardia lamblia Histone deacetylase 0.0014 0.0037 0.0109
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.011 0.0495
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0142
Plasmodium vivax endoplasmin, putative 0.0018 0.0054 0.0361
Schistosoma mansoni retinoic acid receptor RXR 0.0016 0.0047 0.0053
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Loa Loa (eye worm) hypothetical protein 0.0272 0.1409 0.6397
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0014 0.0037 0.0071
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0037 0.0071
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0042 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0016 0.0047 0.0216
Loa Loa (eye worm) hypothetical protein 0.0133 0.0668 0.3027
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0334 0.0385
Schistosoma mansoni histamine h1 receptor 0.0012 0.0026 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0232 0.0814
Toxoplasma gondii MAC/Perforin domain-containing protein 0.0151 0.0765 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0026 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0232 0.0814
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0033 0.0137 0.2013
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0083 0.0312
Schistosoma mansoni kinase 0.0026 0.0099 0.0112
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0133 0.0668 0.0772
Brugia malayi Protein cec-1. 0.0011 0.002 0.0087
Loa Loa (eye worm) hypothetical protein 0.0272 0.1409 0.6397
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1579 0.8366 0.97
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0196 0.0885
Brugia malayi isocitrate dehydrogenase 0.0008 0.0003 0.0008
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0026 0.0028
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1754 0.9293 0.9584
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Echinococcus multilocularis microtubule associated protein 2 0.1344 0.7114 0.8248
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.018 0.0736
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0144 0.1003
Mycobacterium leprae Conserved hypothetical protein 0.0615 0.3234 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0009 0.0007 0.0006
Trypanosoma cruzi polo-like protein kinase, putative 0.0051 0.0232 0.3443
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Onchocerca volvulus 0.0016 0.0045 0.0179
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0022
Toxoplasma gondii histone deacetylase HDAC3 0.0014 0.0037 0.0439
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0042 0.0047
Trypanosoma brucei heat shock protein, putative 0.0018 0.0054 0.0791
Brugia malayi Pre-SET motif family protein 0.0059 0.0276 0.1294
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0082 0.0308
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0146 0.0487
Echinococcus granulosus transcription factor Dp 1 0.0074 0.0357 0.0412
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0029 0.0113 0.0129
Onchocerca volvulus 0.0016 0.0047 0.0189
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0146 0.0151
Onchocerca volvulus 0.0012 0.0023 0.0087
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Schistosoma mansoni endoplasmin 0.0018 0.0054 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0026 0.0028
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0016 0.0045 0.0045
Echinococcus multilocularis Polycystic kidney disease protein 0.0272 0.1409 0.1632
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0026 0.0028
Onchocerca volvulus Netrin receptor homolog 0.0031 0.0126 0.0512
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0133 0.0668 0.4726
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0086 0.1295
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.019 0.2902
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0206 0.3057
Schistosoma mansoni neuropeptide receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0026 0.011
Schistosoma mansoni ap endonuclease 0.0023 0.0082 0.0093
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0016 0.0047 0.0047
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0082 0.0082
Onchocerca volvulus 0.0012 0.0026 0.01
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0082 0.0449
Echinococcus multilocularis chromobox protein 1 0.0068 0.0324 0.0374
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0129 0.0645 0.2377
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0291 0.0336
Echinococcus multilocularis transcription factor Dp 1 0.0074 0.0357 0.0412
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0054 0.0137
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0029 0.0123
Onchocerca volvulus 0.0012 0.0026 0.01
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0149 0.0499
Plasmodium falciparum perforin-like protein 2 0.0151 0.0765 0.5421
Mycobacterium ulcerans hypothetical protein 0.0046 0.0206 0.0206
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0133 0.0668 0.0668
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0291 0.0336
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0649
Onchocerca volvulus 0.0133 0.0668 0.2751
Brugia malayi RE15519p 0.0012 0.0026 0.0114
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0276 0.1247
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0014 0.0033 0.0033
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0033 0.0033
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0146 0.0151
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0133 0.0668 0.1983
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0019 0.0064 0.0072
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Toxoplasma gondii patched family protein 0.0012 0.0023 0.0252
Echinococcus multilocularis Niemann Pick C1 protein 0.0274 0.1419 0.1644
Brugia malayi Nuclear hormone receptor-like 1 0.0009 0.0007 0.0023
Brugia malayi cytochrome P450 0.0016 0.0047 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.019 0.2902
Brugia malayi hypothetical protein 0.0009 0.0007 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0026 0.0028
Treponema pallidum heat shock protein 90 0.0014 0.0035 0.0132
Schistosoma mansoni chromobox protein 0.0068 0.0324 0.0374
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0086 0.0386
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0291 0.1316
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0031 0.0049
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0051 0.0057
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0016 0.0047 0.0047
Entamoeba histolytica heat shock protein 90, putative 0.0018 0.0054 0.0129
Plasmodium vivax perforin-like protein 2 0.0151 0.0765 0.5421
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0033 0.0444
Onchocerca volvulus Bile acid receptor homolog 0.0016 0.0047 0.0189
Loa Loa (eye worm) NADH-ubiquinone oxidoreductase 51 kDa subunit 0.0033 0.0137 0.0616
Brugia malayi hypothetical protein 0.0008 0.0005 0.0014
Trypanosoma brucei heat shock protein, putative 0.0018 0.0054 0.0791
Loa Loa (eye worm) hypothetical protein 0.0097 0.0479 0.2171
Brugia malayi chromobox protein homolog 3 0.0038 0.0164 0.0767
Echinococcus multilocularis serotonin receptor 0.0012 0.0026 0.0028
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0042 0.0047
Echinococcus granulosus orexin receptor type 2 0.0012 0.0026 0.0028
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0082 0.0093
Toxoplasma gondii LsmAD domain-containing protein 0.0013 0.0029 0.0333
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0026 0.0028
Brugia malayi jmjC domain containing protein 0.0015 0.0042 0.0193
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0016 0.0047 0.0659
Trypanosoma cruzi DNA damage repair protein, putative 0.0009 0.0008 0.007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0059 0.0276 0.0319
Brugia malayi Dopamine receptor protein 2 0.0012 0.0026 0.0114
Toxoplasma gondii cytochrome p450 superfamily protein 0.0016 0.0047 0.0574
Trypanosoma brucei DNA damage repair protein, putative 0.0009 0.0008 0.0073
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0209 0.1071 0.1071
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0083 0.0564
Echinococcus multilocularis lipoxygenase domain containing protein 0.0272 0.1409 0.1632
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0026 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0016 0.0047 0.0049
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Onchocerca volvulus 0.0011 0.002 0.0077
Toxoplasma gondii heat shock protein HSP90 0.0018 0.0054 0.0666
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0267 0.0308
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0206 0.0206
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0045 0.0045
Schistosoma mansoni thyroid hormone receptor 0.0016 0.0047 0.0053
Entamoeba histolytica Flap nuclease, putative 0.0014 0.0035 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0084 0.1263
Schistosoma mansoni hypothetical protein 0.0177 0.0905 0.1048
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0149 0.0499
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0031 0.043
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0016 0.0047 0.0053
Schistosoma mansoni amine GPCR 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0086 0.1251
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0033 0.0138 0.0618
Trypanosoma brucei histone deacetylase 3 0.0048 0.0214 0.328
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0016 0.0047 0.0216
Brugia malayi histone deacetylase 11 0.0014 0.0037 0.0166
Brugia malayi CHD4 protein 0.0013 0.0029 0.0128
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0042 0.0047
Plasmodium vivax perforin-like protein 1 0.0151 0.0765 0.5421
Brugia malayi ecdysteroid receptor 0.0016 0.0047 0.0216
Onchocerca volvulus 0.0012 0.0026 0.01
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0126 0.0145
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0334 0.0385
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0016 0.0047 0.0053
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0016 0.0047 0.0047
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0032 0.0132 0.1938
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0146 0.2149
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0146 0.0487
Loa Loa (eye worm) hypothetical protein 0.0133 0.0668 0.3027
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0133 0.0668 0.4726
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0149 0.0499
Loa Loa (eye worm) patched family protein 0.0012 0.0023 0.0095
Loa Loa (eye worm) hypothetical protein 0.0133 0.0668 0.3027
Entamoeba histolytica hypothetical protein 0.007 0.0334 0.1192
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0016 0.0047 0.0208
Loa Loa (eye worm) doublecortin family protein 0.0272 0.1409 0.6397
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Onchocerca volvulus 0.0012 0.0026 0.01
Schistosoma mansoni survival motor neuron protein 0.0047 0.0212 0.0244
Brugia malayi hypothetical protein 0.0272 0.1409 0.6631
Brugia malayi protein C24B5.3 0.0012 0.0023 0.0099
Echinococcus granulosus Ankyrin 0.0031 0.0126 0.0145
Brugia malayi steroid hormone receptor 0.0016 0.0047 0.0216
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0026 0.0114
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Brugia malayi nuclear receptor NHR-88 0.0016 0.0047 0.0216
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0012 0.0012
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0016 0.0047 0.0053
Schistosoma mansoni loxhd1 0.0272 0.1409 0.1632
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0016 0.0047 0.0047
Echinococcus granulosus microtubule associated protein 2 0.1344 0.7114 0.8248
Schistosoma mansoni hypothetical protein 0.0079 0.0383 0.0442
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0026 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0047 0.0053
Schistosoma mansoni hypothetical protein 0.0016 0.0047 0.0053
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0196 0.0226
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0008 0.0003 0.0002
Schistosoma mansoni DNA polymerase IV / kappa 0.0009 0.0008 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.0008
Toxoplasma gondii histone deacetylase HDAC4 0.0014 0.0037 0.0439
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0208
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0149 0.0499
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0649
Brugia malayi Histone deacetylase family protein 0.0048 0.0214 0.1
Trypanosoma brucei histone deacetylase 1 0.0014 0.0037 0.0521
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Brugia malayi Phospholipase A2 family protein 0.0146 0.074 0.348
Trypanosoma cruzi heat shock protein 90, putative 0.0018 0.0054 0.0764
Trypanosoma cruzi heat shock protein 85, putative 0.0018 0.0054 0.0764
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0645 0.9658
Brugia malayi beta-lactamase family protein 0.0035 0.0146 0.0681
Brugia malayi Dopamine receptor protein 1 0.0012 0.0026 0.0114
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0012 0.0012
Toxoplasma gondii histone lysine-specific demethylase 0.0133 0.0668 0.8717
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0016 0.0047 0.0216
Treponema pallidum fructose-bisphosphate aldolase 0.0505 0.2649 1
Echinococcus granulosus histone deacetylase 8 0.0014 0.0037 0.0041
Echinococcus multilocularis sterol regulatory element binding protein 0.0082 0.0399 0.046
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0026 0.0028
Brugia malayi MH2 domain containing protein 0.0061 0.0283 0.1326
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0026 0.011
Schistosoma mansoni hypothetical protein 0.0012 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Plasmodium falciparum ataxin-2 like protein, putative 0.0013 0.0029 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0016 0.0047 0.0216
Plasmodium falciparum lipid/sterol:H+ symporter 0.0012 0.0023 0.0137
Loa Loa (eye worm) hypothetical protein 0.0081 0.0394 0.1785
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0026 0.0028
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0059 0.0276 0.3582
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0026 0.0028
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase I subunit F 0.0033 0.0137 0.0985
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0016 0.0047 0.0047
Plasmodium falciparum histone deacetylase 1 0.0014 0.0037 0.0238
Onchocerca volvulus 0.0012 0.0026 0.01
Chlamydia trachomatis hypothetical protein 0.0151 0.0765 0.6909
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0042 0.0047
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0016 0.0045 0.0045
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0026 0.011
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0031 0.0049
Trypanosoma brucei unspecified product 0.002 0.0066 0.0974
Plasmodium falciparum endoplasmin, putative 0.0011 0.0018 0.0104
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0016 0.0047 0.0049
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0042 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0016 0.0047 0.0216
Loa Loa (eye worm) hypothetical protein 0.0015 0.0042 0.0186
Schistosoma mansoni histone deacetylase 1 2 3 0.0014 0.0037 0.0041
Toxoplasma gondii hypothetical protein 0.0012 0.0023 0.0252
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0083 0.0564
Trichomonas vaginalis esterase, putative 0.0035 0.0146 0.0487
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0149 0.0696
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0407 0.2124 0.9647
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0505 0.2649 1
Plasmodium falciparum histone deacetylase 2 0.0048 0.0214 0.1497
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0026 0.0114
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.002 0.0022
Mycobacterium tuberculosis Conserved protein 0.0035 0.0146 0.0151
Echinococcus granulosus histone deacetylase 0.0048 0.0214 0.0246
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0206 0.0213
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0033 0.0034
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0051 0.0232 0.1047
Leishmania major hypothetical protein, conserved 0.0013 0.0029 0.0382
Onchocerca volvulus Protein patched homolog 0.0012 0.0023 0.0087
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0031 0.0041
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0016 0.0047 0.0047
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0082 0.1177
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0146 0.0681
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0026 0.0028
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0037 0.0071
Plasmodium vivax JmjC domain containing protein 0.0015 0.0042 0.0279
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.002 0.0008
Echinococcus granulosus NADH dehydrogenase ubiquinone flavoprotein 1 0.0033 0.0137 0.0157
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0037 0.0071
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0082 0.0242
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0276 0.0319
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0811 0.0938
Schistosoma mansoni adenoreceptor 0.0012 0.0026 0.0028
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0031 0.0121
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0026 0.0028
Brugia malayi Valyl-tRNA synthetase 0.0011 0.002 0.0087
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0016 0.0047 0.0049
Brugia malayi hypothetical protein 0.0012 0.0023 0.0099
Brugia malayi G-protein coupled receptor 0.0012 0.0026 0.0114
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0016 0.0047 0.0053
Echinococcus granulosus endoplasmin 0.0014 0.0035 0.0039
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0033 0.0147
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0081 0.1021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Brugia malayi G protein-coupled receptor 0.0012 0.0026 0.0114
Trypanosoma cruzi heat shock protein 85, putative 0.0018 0.0054 0.0764
Loa Loa (eye worm) hypothetical protein 0.0023 0.0084 0.0376
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0146 0.0151
Echinococcus granulosus histone deacetylase 6 0.0048 0.0214 0.0246
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) 0.0033 0.0137 0.0141
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Echinococcus multilocularis chromobox protein 2 0.0011 0.002 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0016 0.0047 0.0216
Loa Loa (eye worm) hypothetical protein 0.0146 0.074 0.3357
Entamoeba histolytica hypothetical protein 0.007 0.0334 0.1192
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0016 0.0047 0.0216
Brugia malayi sulfakinin receptor protein 0.0012 0.0026 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Trypanosoma cruzi histone deacetylase, putative 0.0048 0.0214 0.3167
Entamoeba histolytica histone deacetylase, putative 0.0014 0.0037 0.0063
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0047 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.019 0.2902
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Echinococcus granulosus Chromobox protein 3 0.0011 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0208
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0144 0.0624
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0026 0.0028
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0042 0.0186
Trichomonas vaginalis histone deacetylase, putative 0.0014 0.0037 0.0071
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0045 0.0204
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0029 0.0113 0.0507
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Brugia malayi ImpB/MucB/SamB family protein 0.0029 0.0113 0.0526
Brugia malayi Doublecortin family protein 0.0272 0.1409 0.6631
Giardia lamblia Heat shock protein HSP 90-alpha 0.0014 0.0035 0.0102
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0291 0.0336
Echinococcus granulosus lipoxygenase domain containing protein 0.0272 0.1409 0.1632
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0129 0.0645 0.2924
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.002 0.012
Brugia malayi histone deacetylase 3 (HD3) 0.0014 0.0037 0.0166
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0014 0.0035 0.0036
Schistosoma mansoni hypothetical protein 0.0044 0.0193 0.0222
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0208
Echinococcus multilocularis dna polymerase kappa 0.0043 0.019 0.0218
Echinococcus granulosus allatostatin A receptor 0.0012 0.0026 0.0028
Schistosoma mansoni heat shock protein 0.0018 0.0054 0.0061
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Schistosoma mansoni biogenic amine receptor 0.0012 0.0026 0.0028
Trypanosoma brucei histone deacetylase 2 0.0014 0.0037 0.0521
Trypanosoma cruzi histone deacetylase, putative 0.0048 0.0214 0.3167
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0657
Trypanosoma cruzi polo-like protein kinase, putative 0.0051 0.0232 0.3443
Echinococcus multilocularis heat shock protein 0.0018 0.0054 0.0061
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0146 0.0487
Brugia malayi N-terminal motif family protein 0.0097 0.0479 0.225
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0026 0.0028
Echinococcus multilocularis histone deacetylase 3 0.0014 0.0037 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Echinococcus granulosus Chromo domain 0.0011 0.002 0.0022
Echinococcus multilocularis lipoxygenase domain containing protein 0.0272 0.1409 0.1632
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0031 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0232 0.0814
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0051 0.0232 0.0267
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0142
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0026 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.019 0.2902
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0232 0.1194 0.542
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0009 0.0008 0.0061
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Brugia malayi Pre-SET motif family protein 0.0407 0.2124 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.002 0.0008
Leishmania major cytochrome p450-like protein 0.0016 0.0047 0.0659
Brugia malayi jmjC domain containing protein 0.0015 0.0042 0.0193
Schistosoma mansoni hypothetical protein 0.0079 0.0383 0.0442
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0208
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0149 0.0491
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0029 0.0031
Brugia malayi jmjC domain containing protein 0.0015 0.0042 0.0193
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0324 0.1164
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0026 0.0028
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0206 0.0542
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0026 0.0028
Leishmania major NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0033 0.0137 0.2013
Loa Loa (eye worm) hypothetical protein 0.0033 0.0138 0.0618
Brugia malayi jmjC domain containing protein 0.0058 0.0267 0.1253
Plasmodium vivax perforin-like protein 3 0.0151 0.0765 0.5421
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0008 0.0003 0.0003
Onchocerca volvulus Histone deacetylase 10 homolog 0.0014 0.0037 0.0145
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0021 0.009
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0026 0.0028
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0026 0.0114
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0042 0.0047
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0016 0.0047 0.0049
Brugia malayi Serotonin receptor 0.0012 0.0026 0.0114
Schistosoma mansoni hypothetical protein 0.0177 0.0905 0.1048
Onchocerca volvulus 0.0035 0.0146 0.0597
Onchocerca volvulus Protein patched homolog 0.0012 0.0023 0.0087
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0051 0.0232 0.0267
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0016 0.0045 0.0045
Schistosoma mansoni endoplasmin 0.0018 0.0054 0.0061
Leishmania major DNA polymerase eta, putative 0.0042 0.0186 0.2754
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0196 0.0226
Loa Loa (eye worm) patched family protein 0.0012 0.0023 0.0095
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0146 0.0487
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0016 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0038 0.0164 0.074
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0042 0.0279
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0054 0.0137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0016 0.0047 0.0208
Onchocerca volvulus NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial homolog 0.0018 0.0055 0.0222
Echinococcus granulosus Protein patched homolog 1 0.0082 0.0399 0.046
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0033 0.0147
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0045 0.0204
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0033 0.0444
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Onchocerca volvulus 0.0011 0.002 0.0077
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.002 0.0008
Trypanosoma cruzi DNA damage repair protein, putative 0.0009 0.0008 0.007
Toxoplasma gondii ABC1 family protein 0.0035 0.0146 0.1873
Trypanosoma cruzi heat shock protein 85, putative 0.0014 0.0035 0.0477
Trichomonas vaginalis heat shock protein, putative 0.0018 0.0054 0.0137
Loa Loa (eye worm) transcription factor SMAD2 0.0061 0.0283 0.1279
Brugia malayi hypothetical protein 0.0012 0.0023 0.0099
Brugia malayi Death domain containing protein 0.0031 0.0126 0.0585
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0505 0.2649 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0047 0.0659
Schistosoma mansoni histone deacetylase 4 5 0.0048 0.0214 0.0246
Loa Loa (eye worm) MH2 domain-containing protein 0.0061 0.0283 0.1279
Echinococcus multilocularis Niemann Pick C1 protein 0.0192 0.0981 0.1136
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Mycobacterium tuberculosis Conserved protein 0.0035 0.0146 0.0151
Onchocerca volvulus 0.0012 0.0026 0.01
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0149 0.1915
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0036 0.0068
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0016 0.0047 0.0049
Echinococcus multilocularis Ankyrin 0.0031 0.0126 0.0145
Schistosoma mansoni amine oxidase 0.0133 0.0668 0.0772
Echinococcus granulosus heat shock protein 90 0.0014 0.0035 0.0039
Schistosoma mansoni heat shock protein 0.0018 0.0054 0.0061
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0026 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0033 0.0033
Onchocerca volvulus 0.007 0.0336 0.138
Loa Loa (eye worm) hypothetical protein 0.0133 0.0668 0.3027
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0016 0.0047 0.0659
Onchocerca volvulus Phospholipase A2 homolog 0.0146 0.074 0.3051
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0219 0.0755
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.002 0.0087
Trypanosoma cruzi heat shock protein 90, putative 0.0014 0.0035 0.0477
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0149 0.0491
Echinococcus multilocularis histone deacetylase 6 0.0048 0.0214 0.0246
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0026 0.0114
Echinococcus granulosus netrin receptor unc 5 0.0031 0.0126 0.0144
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0811 0.0938
Mycobacterium ulcerans beta-lactamase 0.0035 0.0146 0.0146
Trypanosoma brucei DNA damage repair protein, putative 0.0009 0.0008 0.0073
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0082 0.0242
Echinococcus granulosus histone deacetylase 1 0.0014 0.0037 0.0041
Toxoplasma gondii heat shock protein 90, putative 0.0018 0.0054 0.0666
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0026 0.0028
Schistosoma mansoni Replicative DNA helicase 0.0209 0.1071 0.124
Brugia malayi larval opioid receptor 0.0012 0.0026 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0505 0.2649 1
Brugia malayi heat shock protein 90 0.0018 0.0054 0.0247
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0016 0.0047 0.0208
Loa Loa (eye worm) hypothetical protein 0.0133 0.0668 0.3027
Trypanosoma brucei histone deacetylase 4 0.0048 0.0214 0.328
Echinococcus granulosus histone deacetylase 7 0.0048 0.0214 0.0246
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0042 0.0589
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0016 0.0045 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.016
Brugia malayi Patched family protein 0.0012 0.0023 0.0099
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0009 0.0007 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0016 0.0047 0.0049
Leishmania major DNA polymerase kappa, putative 0.0009 0.0008 0.007
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0021 0.0023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0146 0.0168
Brugia malayi Endoplasmin precursor 0.0018 0.0054 0.0247
Brugia malayi Dopamine receptor 0.0012 0.0026 0.0114
Plasmodium falciparum protoporphyrinogen oxidase 0.0133 0.0668 0.4726
Echinococcus multilocularis cpg binding protein 0.003 0.0119 0.0136
Plasmodium vivax SET domain protein, putative 0.0059 0.0276 0.1942
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0206 0.0965
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0026 0.0114
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0035 0.0065
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0033 0.0147
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Schistosoma mansoni hypothetical protein 0.007 0.0334 0.0385
Leishmania major heat shock protein 83-1 0.0018 0.0054 0.0764
Echinococcus granulosus heat shock protein 0.0018 0.0054 0.0061
Trypanosoma brucei Heat shock protein 83, putative 0.0018 0.0054 0.0791
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0016 0.0047 0.0216
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0026 0.0028
Onchocerca volvulus 0.0014 0.0033 0.0129
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0016 0.0047 0.0049
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0014 0.0035 0.0484
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0026 0.0028
Plasmodium vivax heterochromatin protein 1, putative 0.0011 0.002 0.012
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0144 0.0144
Brugia malayi CXXC zinc finger family protein 0.0028 0.011 0.0513
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0095
Brugia malayi hypothetical protein 0.0012 0.0026 0.0114
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1829 0.9697 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.011
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0026 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0276 0.0319
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0206 0.0709
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0047 0.0053
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0082 0.0363

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.