Detailed information for compound 1462631

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 381.483 | Formula: C24H28FNO2
  • H donors: 1 H acceptors: 2 LogP: 3.39 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccccc1/C(=C\CCN1CCC[C@H](C1)C(=O)O)/c1ccccc1F
  • InChi: 1S/C24H28FNO2/c1-2-18-9-3-4-11-20(18)21(22-12-5-6-14-23(22)25)13-8-16-26-15-7-10-19(17-26)24(27)28/h3-6,9,11-14,19H,2,7-8,10,15-17H2,1H3,(H,27,28)/b21-13+/t19-/m1/s1
  • InChiKey: JFXUNHMGUSTRHG-DBRLUCFCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Sodium- and chloride-dependent GABA transporter 3, putative Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma japonicum Sodium- and chloride-dependent GABA transporter 2, putative Get druggable targets OG5_126944 All targets in OG5_126944
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma japonicum Sodium- and chloride-dependent creatine transporter 1, putative Get druggable targets OG5_126944 All targets in OG5_126944
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma japonicum ko:K05046 solute carrier family 6 (neurotransmitter transporter, GABA), member, putative Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_126944 All targets in OG5_126944
Echinococcus multilocularis sodium:chloride dependent neurotransmitter Get druggable targets OG5_126944 All targets in OG5_126944
Echinococcus granulosus sodium:chloride dependent neurotransmitter Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma japonicum ko:K10420 dynein light chain Tctex-type 1, putative Get druggable targets OG5_126944 All targets in OG5_126944
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter Get druggable targets OG5_126944 All targets in OG5_126944
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative solute carrier family 6 (neurotransmitter transporter), member 1 599 aa 606 aa 22.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0019 0.002 0.0035
Trypanosoma brucei calpain-like protein, putative 0.006 0.0156 0.0339
Schistosoma mansoni cathepsin B (C01 family) 0.0128 0.0377 0.0801
Schistosoma mansoni reticulocalbin 0.0014 0.0006 0.0007
Echinococcus multilocularis X box binding protein 1 0.0134 0.0398 0.0843
Echinococcus granulosus beta LACTamase domain containing family member 0.016 0.0482 0.0921
Brugia malayi cathepsin F-like cysteine proteinase 0.0185 0.0562 0.1859
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0025 0.004 0.0125
Echinococcus granulosus neuronal calcium sensor 0.0014 0.0004 0.0001
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0128 0.0376 0.1243
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.006 0.0156 0.0339
Brugia malayi calpain 7 0.006 0.0156 0.0512
Echinococcus multilocularis beta LACTamase domain containing family member 0.016 0.0482 0.1023
Loa Loa (eye worm) calpain family protein 1 0.0118 0.0344 0.0342
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0014 0.0004 0.0002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0014 0.0006 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0128 0.0377 0.2008
Echinococcus granulosus cpg binding protein 0.0015 0.0008 0.0009
Echinococcus granulosus Niemann Pick C1 protein 0.0046 0.0109 0.0203
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Echinococcus granulosus aldo keto reductase 0.0025 0.004 0.007
Loa Loa (eye worm) leucyl aminopeptidase 0.0014 0.0003 0.0001
Loa Loa (eye worm) serotonin transporter b 0.0019 0.002 0.0018
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0327 0.1028 0.1972
Onchocerca volvulus 0.016 0.0482 0.2578
Echinococcus granulosus calpain A 0.006 0.0156 0.0294
Trichomonas vaginalis calmodulin, putative 0.0014 0.0004 0.0004
Echinococcus granulosus GA binding protein alpha chain 0.0044 0.0103 0.0192
Trypanosoma cruzi centrin, putative 0.0014 0.0004 0.0002
Echinococcus granulosus fetal alzheimer antigen falz 0.0014 0.0005 0.0003
Echinococcus granulosus short transient receptor potential channel 6 0.0038 0.0083 0.0153
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0017 0.0015 0.0035
Trypanosoma brucei Component of motile flagella 41 0.0014 0.0004 0.0002
Echinococcus granulosus tar DNA binding protein 0.0074 0.0202 0.0382
Plasmodium falciparum glutathione reductase 0.0017 0.0015 0.0079
Toxoplasma gondii histone lysine methyltransferase SET1 0.0028 0.0049 0.0262
Echinococcus granulosus histone lysine methyltransferase setb 0.0039 0.0088 0.0162
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0039 0.0088 0.0182
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.006 0.0156 0.0339
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.016 0.0482 0.1452
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0459 0.245
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0202 0.0664
Loa Loa (eye worm) hypothetical protein 0.0057 0.0146 0.0144
Plasmodium vivax hypothetical protein, conserved 0.016 0.0482 0.2587
Schistosoma mansoni glutaminyl-peptide cyclotransferase-related 0.0014 0.0003 0.0003
Plasmodium falciparum serine repeat antigen 7 0.0128 0.0377 0.2022
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0025 0.004 0.0125
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Onchocerca volvulus 0.0045 0.0105 0.0552
Loa Loa (eye worm) thioredoxin reductase 0.0017 0.0015 0.0013
Leishmania major phospholipase c-like protein 0.0014 0.0004 0.0002
Echinococcus multilocularis Niemann Pick C1 protein 0.0066 0.0173 0.0363
Brugia malayi calcium-binding protein 0.0014 0.0004 0.0006
Schistosoma mansoni calmodulin related calcium binding protein 0.0014 0.0004 0.0004
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0943 0.3038 0.6486
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0583 0.1864 1
Echinococcus multilocularis microtubule associated protein 2 0.0639 0.2048 0.4369
Giardia lamblia Cathepsin L precursor 0.0128 0.0377 0.313
Trypanosoma brucei caltractin, putative 0.0014 0.0004 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0287 0.1525
Brugia malayi beta-lactamase family protein 0.016 0.0482 0.1595
Echinococcus granulosus Smad4 0.0027 0.0047 0.0084
Plasmodium falciparum serine repeat antigen 6 0.0128 0.0377 0.2022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0377 0.2008
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.002 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.048
Echinococcus multilocularis cysteine protease 0.0583 0.1864 0.3976
Loa Loa (eye worm) hypothetical protein 0.0039 0.0085 0.0083
Loa Loa (eye worm) programmed cell death protein 6 0.0014 0.0006 0.0003
Schistosoma mansoni 6-phosphofructokinase 0.0077 0.0212 0.0448
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0027 0.0128
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Brugia malayi MH2 domain containing protein 0.0027 0.0047 0.015
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0159 0.0477 0.1012
Toxoplasma gondii peptidase, M28 family protein 0.0014 0.0003 0.0018
Trypanosoma cruzi calmodulin, putative 0.0014 0.0004 0.0002
Plasmodium vivax vivapain-3 0.0313 0.098 0.5257
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0199 0.061 0.1299
Loa Loa (eye worm) hypothetical protein 0.0038 0.0082 0.008
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0159 0.0477 0.1015
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0128 0.0377 0.2008
Trichomonas vaginalis set domain proteins, putative 0.023 0.0711 0.3801
Onchocerca volvulus 0.0014 0.0004 0.001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.002 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0459 0.245
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1023 0.3302 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0146 0.0144
Mycobacterium tuberculosis Probable oxidoreductase 0.0025 0.004 0.011
Brugia malayi Pre-SET motif family protein 0.0029 0.0054 0.0174
Trypanosoma cruzi I/6 autoantigen, putative 0.0014 0.0004 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.016 0.0482 0.1061
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.002 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Plasmodium vivax vivapain-2 0.0583 0.1864 1
Brugia malayi calpain 5 0.0042 0.0097 0.0315
Echinococcus granulosus Niemann Pick C1 protein 0.0066 0.0173 0.0327
Trypanosoma brucei calpain, putative 0.0018 0.0018 0.0033
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.006 0.0156 0.0339
Plasmodium falciparum serine repeat antigen 9 0.0128 0.0377 0.2022
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0202 0.0427
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0128 0.0377 0.2022
Entamoeba histolytica phosphofructokinase, putative 0.0077 0.0212 0.1117
Brugia malayi MH2 domain containing protein 0.0397 0.1255 0.4162
Plasmodium vivax serine-repeat antigen (SERA) 0.0128 0.0377 0.2022
Schistosoma mansoni peptidase Clp (S14 family) 0.0036 0.0078 0.0162
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0036 0.0078 0.1562
Brugia malayi MH1 domain containing protein 0.0015 0.0008 0.0019
Trichomonas vaginalis calmodulin-2, putative 0.0014 0.0004 0.0004
Echinococcus granulosus cathepsin b 0.0935 0.3012 0.5789
Echinococcus granulosus hypothetical protein 0.0025 0.004 0.007
Schistosoma mansoni transient receptor potential channel 0.0057 0.0146 0.0307
Trypanosoma cruzi calpain cysteine peptidase, putative 0.006 0.0156 0.0339
Entamoeba histolytica hypothetical protein 0.0069 0.0183 0.0963
Loa Loa (eye worm) hypothetical protein 0.0143 0.0425 0.0423
Brugia malayi Latrophilin receptor protein 2 0.0143 0.0425 0.1405
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0014 0.0006 0.0005
Giardia lamblia Cathepsin L precursor 0.0128 0.0377 0.313
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0014 0.0004 0.0002
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0047 0.0111 0.0233
Schistosoma mansoni ets-related 0.0134 0.0396 0.0841
Giardia lamblia Hypothetical protein 0.0128 0.0377 0.313
Plasmodium falciparum transporter, putative 0.0019 0.002 0.0105
Onchocerca volvulus Cathepsin L homolog 0.0128 0.0377 0.2013
Trypanosoma cruzi aldo/keto reductase, putative 0.0025 0.004 0.0081
Brugia malayi beta-lactamase family protein 0.016 0.0482 0.1595
Brugia malayi calpain 5 0.0018 0.0018 0.0054
Loa Loa (eye worm) hypothetical protein 0.0636 0.2035 0.2034
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.048
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Plasmodium vivax unspecified product 0.0128 0.0377 0.2022
Brugia malayi follicle stimulating hormone receptor 0.0175 0.0532 0.1759
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.004 0.007
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0069 0.0183 0.0346
Loa Loa (eye worm) nuclear factor I 0.0015 0.0008 0.0006
Echinococcus multilocularis Niemann Pick C1 protein 0.0046 0.0109 0.0226
Toxoplasma gondii phosphofructokinase PFKII 0.0021 0.0027 0.0146
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0085
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0583 0.1864 0.3976
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0004
Onchocerca volvulus 0.0019 0.002 0.0094
Brugia malayi hypothetical protein 0.0178 0.054 0.1788
Leishmania major programmed cell death 6 protein-like protein 0.0014 0.0004 0.0002
Schistosoma mansoni pol-related 0.0025 0.004 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0313 0.098 0.2164
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0036 0.0078 0.369
Entamoeba histolytica cysteine protease, putative 0.0128 0.0377 0.2005
Brugia malayi MH2 domain containing protein 0.0027 0.0047 0.015
Toxoplasma gondii calmodulin CAM1 0.0014 0.0006 0.003
Onchocerca volvulus 0.0043 0.0101 0.053
Brugia malayi Calcitonin receptor-like protein seb-1 0.0451 0.1432 0.475
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Onchocerca volvulus 0.0128 0.0377 0.2013
Loa Loa (eye worm) matrixin family protein 0.0096 0.0274 0.0271
Plasmodium vivax glutathione reductase, putative 0.0017 0.0015 0.0079
Trypanosoma brucei Calpain-like protein CALP1.3 0.0018 0.0018 0.0033
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0202 0.02
Onchocerca volvulus 0.023 0.0711 0.3805
Giardia lamblia Aldose reductase 0.0025 0.004 0.0288
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0683 0.219 0.7267
Echinococcus multilocularis transient receptor potential gamma protein 0.0057 0.0146 0.0305
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.0076
Loa Loa (eye worm) cysteine protease 0.0583 0.1864 0.1862
Toxoplasma gondii EFHC1, putative 0.0014 0.0004 0.0022
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.002 0.0058
Leishmania major hypothetical protein, conserved 0.016 0.0482 0.1061
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0065 0.0171 0.056
Brugia malayi Matrixin family protein 0.0043 0.0101 0.0328
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0203 0.0622 0.1191
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0018 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0043 0.0101 0.0099
Trypanosoma brucei centrin, putative 0.0014 0.0004 0.0002
Brugia malayi cathepsin L-like cysteine proteinase 0.0128 0.0377 0.1245
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.002 0.0105
Schistosoma mansoni calpain (C02 family) 0.006 0.0156 0.0329
Trypanosoma brucei centrin, putative 0.0014 0.0004 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0128 0.0377 0.2008
Loa Loa (eye worm) hypothetical protein 0.0089 0.0248 0.0246
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.1446 0.4683 1
Loa Loa (eye worm) beta-lactamase 0.016 0.0482 0.048
Onchocerca volvulus Matrix metalloproteinase homolog 0.0096 0.0274 0.1458
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0018 0.008
Schistosoma mansoni calpain-7 (C02 family) 0.006 0.0156 0.0329
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0313 0.098 0.2089
Giardia lamblia Cathepsin B precursor 0.0128 0.0377 0.313
Loa Loa (eye worm) hypothetical protein 0.0043 0.0101 0.0099
Trypanosoma cruzi cysteine peptidase, putative 0.0185 0.0562 0.1238
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0202 0.02
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0378 0.1192 0.2634
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0014 0.0005 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0027 0.0128
Mycobacterium ulcerans glutaminase 0.0121 0.0355 0.7345
Schistosoma mansoni gabp alpha 0.0044 0.0103 0.0215
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0031
Echinococcus granulosus GPCR family 2 0.0143 0.0425 0.0811
Trypanosoma cruzi kinesin, putative 0.0042 0.0097 0.0207
Trypanosoma cruzi cysteine peptidase, putative 0.1395 0.4516 1
Trypanosoma brucei calpain-like protein, putative 0.006 0.0156 0.0339
Brugia malayi Cathepsin L-like precursor 0.0399 0.1261 0.4183
Brugia malayi Matrixin family protein 0.0043 0.0101 0.0328
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Leishmania major hypothetical protein, unknown function 0.0018 0.0018 0.0033
Loa Loa (eye worm) latrophilin receptor protein 2 0.0143 0.0425 0.0423
Loa Loa (eye worm) glutaminase 0.0121 0.0355 0.0353
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0014 0.0004 0.0002
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0019 0.002 0.0031
Echinococcus multilocularis aldo keto reductase 0.0025 0.004 0.0078
Schistosoma mansoni Fxna peptidase (M28 family) 0.0014 0.0003 0.0003
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0025 0.004 0.0196
Schistosoma mansoni hypothetical protein 0.0019 0.0021 0.004
Trichomonas vaginalis penicillin-binding protein, putative 0.016 0.0482 0.2573
Trypanosoma cruzi cysteine peptidase, putative 0.1395 0.4516 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Trichomonas vaginalis centrin, putative 0.0014 0.0004 0.0004
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0047 0.0045
Echinococcus granulosus cysteine protease 0.0313 0.098 0.1879
Giardia lamblia Cysteine protease 0.0128 0.0377 0.313
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0241 0.0745 0.1587
Schistosoma mansoni ef hand domain family member A2 0.0014 0.0004 0.0004
Toxoplasma gondii ABC1 family protein 0.016 0.0482 0.2587
Trypanosoma brucei Calpain-like protein 1.2 0.0018 0.0018 0.0033
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0583 0.1864 0.3976
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Echinococcus multilocularis cysteine protease 0.0583 0.1864 0.3976
Brugia malayi leucyl aminopeptidase 0.0014 0.0003 0.0004
Loa Loa (eye worm) norepinephrine transporter 0.0019 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0118 0.0344 0.0342
Trichomonas vaginalis calcineurin B subunit, putative 0.0014 0.0006 0.0012
Onchocerca volvulus 0.0178 0.054 0.2891
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0014 0.0004 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0039 0.0088 0.018
Trypanosoma cruzi kinesin, putative 0.0042 0.0097 0.0207
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0027 0.0047 0.0094
Trypanosoma brucei centrin-3 0.0014 0.0004 0.0002
Brugia malayi glutathione reductase 0.0017 0.0015 0.0042
Loa Loa (eye worm) hypothetical protein 0.0142 0.0423 0.0421
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0069 0.0186 0.0184
Brugia malayi beta-lactamase 0.016 0.0482 0.1595
Leishmania major centrin, putative 0.0014 0.0004 0.0002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0199 0.061 0.1167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Echinococcus granulosus aldo keto reductase 0.0025 0.004 0.007
Entamoeba histolytica cysteine proteinase, putative 0.0399 0.1261 0.6759
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0001
Onchocerca volvulus Fxna peptidase homolog 0.0014 0.0003 0.0007
Loa Loa (eye worm) transcription factor SMAD2 0.0397 0.1255 0.1253
Plasmodium vivax serine-repeat antigen (SERA) 0.0128 0.0377 0.2022
Brugia malayi Papain family cysteine protease containing protein 0.0583 0.1864 0.6185
Loa Loa (eye worm) oxidoreductase 0.0025 0.004 0.0038
Loa Loa (eye worm) calpain family protein 1 0.016 0.0482 0.048
Onchocerca volvulus Cathepsin L homolog 0.0583 0.1864 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.0107
Echinococcus multilocularis calpain 0.006 0.0156 0.0327
Brugia malayi Papain family cysteine protease containing protein 0.0313 0.098 0.3248
Loa Loa (eye worm) matrixin family protein 0.015 0.0449 0.0447
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Echinococcus granulosus cathepsin L cysteine protease 0.0313 0.098 0.1879
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0036 0.0078 0.162
Trichomonas vaginalis calmodulin, putative 0.0014 0.0004 0.0004
Brugia malayi hypothetical protein 0.0057 0.0146 0.0477
Mycobacterium ulcerans beta-lactamase 0.016 0.0482 1
Trichomonas vaginalis calcium binding protein, putative 0.0014 0.0004 0.0004
Brugia malayi Matrixin family protein 0.015 0.0449 0.1486
Plasmodium vivax amine transporter, putative 0.0019 0.002 0.0105
Trichomonas vaginalis phosphofructokinase, putative 0.0077 0.0212 0.112
Echinococcus granulosus mothers against decapentaplegic 5 0.0027 0.0047 0.0084
Toxoplasma gondii hypothetical protein 0.0019 0.002 0.0105
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0054 0.0292
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.006 0.0156 0.0339
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0128 0.0377 0.2022
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0128 0.0377 0.2008
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0583 0.1864 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0021 0.0027 0.1286
Loa Loa (eye worm) solute carrier family 6 member 4 0.0019 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0001
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0039 0.0086 0.0252
Echinococcus multilocularis short transient receptor potential channel 6 0.0038 0.0083 0.0169
Schistosoma mansoni cathepsin s 0.0185 0.0562 0.1196
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0128 0.0377 0.0801
Echinococcus multilocularis calpain 7 (C02 family) 0.006 0.0156 0.0327
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Toxoplasma gondii hypothetical protein 0.0018 0.0018 0.0098
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0174 0.0527 0.1122
Brugia malayi cathepsin Z-like cysteine proteinase 0.0128 0.0377 0.1245
Schistosoma mansoni dihydroceramide desaturase 0.0197 0.0603 0.1284
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0128 0.0377 0.0801
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0153 0.0459 0.1518
Echinococcus multilocularis hypothetical protein 0.006 0.0156 0.0327
Plasmodium falciparum ataxin-2 like protein, putative 0.0045 0.0104 0.056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0153 0.0459 0.0457
Onchocerca volvulus 0.0029 0.0054 0.0281
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0378 0.1192 0.2634
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0027 0.0128
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.002 0.0024 0.0044
Plasmodium falciparum ataxin-2 like protein, putative 0.0045 0.0104 0.056
Echinococcus granulosus serotonin transporter 0.0019 0.002 0.0031
Echinococcus multilocularis aldehyde reductase 0.0018 0.0016 0.0028
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0128 0.0377 0.0801
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0935 0.3012 0.6431
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0451 0.1432 0.143
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.002 0.0058
Brugia malayi latrophilin 2 splice variant baaae 0.0308 0.0966 0.3202
Loa Loa (eye worm) disintegrin family protein 0.0039 0.0085 0.0083
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0026
Schistosoma mansoni peptidylglycine monooxygenase 0.0128 0.0376 0.08
Brugia malayi EF hand family protein 0.0014 0.0004 0.0006
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Loa Loa (eye worm) oxidoreductase 0.0025 0.004 0.0038
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0014 0.0004 0.0002
Brugia malayi Cathepsin L-like cysteine proteinase 0.0399 0.1261 0.4183
Echinococcus multilocularis cathepsin L 0.0313 0.098 0.2087
Toxoplasma gondii 6-phosphofructokinase 0.0021 0.0027 0.0146
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0018 0.0018 0.008
Echinococcus multilocularis EF hand domain containing family member A2 0.0014 0.0006 0.0005
Brugia malayi Papain family cysteine protease containing protein 0.0128 0.0377 0.1245
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0287 0.1525
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0018 0.0018 0.008
Schistosoma mansoni hypothetical protein 0.0134 0.0398 0.0846
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0128 0.0377 0.2022
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Trypanosoma cruzi caltractin, putative 0.0014 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0219 0.0675 0.0673
Onchocerca volvulus Cathepsin L homolog 0.0583 0.1864 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0018 0.0033
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0039 0.0086 0.1792
Brugia malayi Transient-receptor-potential like protein 0.0021 0.0029 0.0088
Trypanosoma cruzi cysteine peptidase, putative 0.0583 0.1864 0.4123
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.048
Toxoplasma gondii hypothetical protein 0.0019 0.002 0.0105
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0006 0.003
Mycobacterium tuberculosis Probable reductase 0.0039 0.0086 0.0252
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0128 0.0377 0.313
Entamoeba histolytica grainin, putative 0.0014 0.0006 0.0008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Brugia malayi hypothetical protein 0.0277 0.0862 0.2858
Onchocerca volvulus Matrilysin homolog 0.0043 0.0101 0.053
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0014 0.0004 0.0002
Trichomonas vaginalis myosin light chain 1, putative 0.0014 0.0004 0.0004
Echinococcus granulosus EF hand domain containing family member A2 0.0014 0.0006 0.0004
Echinococcus granulosus TRP transient receptor potential channel 0.0021 0.0029 0.0048
Toxoplasma gondii troponin c, isotype gamma, putative 0.0014 0.0004 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0128 0.0377 0.2008
Trypanosoma cruzi cruzipain precursor, putative 0.1395 0.4516 1
Entamoeba histolytica cysteine proteinase, putative 0.0313 0.098 0.5246
Onchocerca volvulus 0.0583 0.1864 1
Echinococcus multilocularis cathepsin b 0.0935 0.3012 0.643
Brugia malayi Ets-domain containing protein 0.0044 0.0103 0.0335
Brugia malayi calpain family protein 1 0.016 0.0482 0.1594
Brugia malayi EF hand family protein 0.0014 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0069 0.0186 0.0184
Loa Loa (eye worm) 6-phosphofructokinase 0.0077 0.0212 0.021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0014 0.0004 0.0004
Schistosoma mansoni transient receptor potential channel 0.0038 0.0083 0.0172
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0039 0.0086 0.0252
Giardia lamblia Cathepsin B precursor 0.0128 0.0377 0.313
Onchocerca volvulus 0.016 0.0482 0.2578
Trypanosoma cruzi PAB1-binding protein , putative 0.0045 0.0104 0.0224
Loa Loa (eye worm) reprolysin 0.0159 0.0477 0.0475
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Echinococcus multilocularis expressed conserved protein 0.0043 0.01 0.0206
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0583 0.1864 1
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Brugia malayi Cathepsin L-like precursor 0.0583 0.1864 0.6185
Mycobacterium tuberculosis Probable esterase LipL 0.016 0.0482 0.1452
Echinococcus multilocularis Smad4 0.0027 0.0047 0.0094
Trypanosoma cruzi cysteine protease, putative 0.0313 0.098 0.2164
Echinococcus granulosus neurocalcin 0.0014 0.0004 0.0001
Leishmania major hypothetical protein, conserved 0.0014 0.0006 0.0005
Giardia lamblia Cysteine protease 0.0128 0.0377 0.313
Echinococcus multilocularis protein patched 0.002 0.0023 0.0043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0583 0.1864 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.004 0.007
Schistosoma mansoni hypothetical protein 0.0019 0.0021 0.004
Onchocerca volvulus Huntingtin homolog 0.0057 0.0146 0.0771
Brugia malayi glutaminase DH11.1 0.0121 0.0355 0.1172
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Schistosoma mansoni smad1 5 8 and 0.0027 0.0047 0.0096
Toxoplasma gondii LsmAD domain-containing protein 0.0045 0.0104 0.056
Schistosoma mansoni calmodulin 0.0014 0.0004 0.0004
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.016 0.0482 0.1025
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0018
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0014 0.0004 0.0004
Trichomonas vaginalis aldo/keto reductase, putative 0.0025 0.004 0.0196
Onchocerca volvulus 0.0583 0.1864 1
Schistosoma mansoni smad1 5 8 and 0.0027 0.0047 0.0096
Echinococcus granulosus X box binding protein 1 0.0134 0.0398 0.0759
Onchocerca volvulus Fxna peptidase homolog 0.0014 0.0003 0.0007
Brugia malayi MH1 domain containing protein 0.0027 0.0047 0.015
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0202 0.0424
Giardia lamblia Cathepsin B precursor 0.0128 0.0377 0.313
Giardia lamblia Cathepsin B precursor 0.0128 0.0377 0.313
Brugia malayi ADAM-TS Spacer 1 family protein 0.0118 0.0344 0.1137
Giardia lamblia Cathepsin L-like protease 0.0128 0.0377 0.313
Giardia lamblia Cathepsin B precursor 0.0378 0.1192 1
Plasmodium falciparum serine repeat antigen 4 0.0128 0.0377 0.2022
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0174 0.0527 0.1119
Brugia malayi fibroinase precursor 0.0128 0.0377 0.1245
Leishmania major cathepsin L-like protease 0.0583 0.1864 0.4123
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0018 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0016
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.006 0.0156 0.0339
Trichomonas vaginalis calcium binding proteins, putative 0.0014 0.0004 0.0004
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0943 0.3038 0.5839
Toxoplasma gondii centrin 0.0014 0.0004 0.0022
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Trichomonas vaginalis centrin, putative 0.0014 0.0004 0.0004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0378 0.1192 0.2542
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.002 0.0031
Trypanosoma brucei trypanothione reductase 0.0017 0.0015 0.0025
Leishmania major calmodulin-like protein 0.0014 0.0004 0.0002
Trichomonas vaginalis calmodulin, putative 0.0014 0.0004 0.0004
Leishmania major centrin, putative,caltractin, putative 0.0014 0.0004 0.0002
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0128 0.0377 0.2022
Echinococcus multilocularis peptidase Clp (S14 family) 0.0024 0.0037 0.0072
Brugia malayi MH1 domain containing protein 0.0027 0.0047 0.015
Echinococcus multilocularis calcium uptake protein 1 0.0014 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0159 0.0477 0.0475
Brugia malayi phosphofructokinase 0.0077 0.0212 0.0696
Loa Loa (eye worm) EF hand family protein 0.0014 0.0004 0.0002
Echinococcus multilocularis calbindin 32 0.0014 0.0006 0.0005
Mycobacterium leprae PROBABLE HYDROLASE 0.0053 0.0132 0.2731
Toxoplasma gondii thioredoxin reductase 0.0017 0.0015 0.0079
Echinococcus granulosus smad 0.0027 0.0047 0.0084
Echinococcus multilocularis calumenin 0.0014 0.0006 0.0005
Schistosoma mansoni smad1 5 8 and 0.0027 0.0047 0.0096
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0128 0.0377 0.2022
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0045 0.0105 0.0342
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Mycobacterium leprae conserved hypothetical protein 0.016 0.0482 1
Loa Loa (eye worm) hypothetical protein 0.0128 0.0376 0.0374
Mycobacterium ulcerans esterase/lipase LipP 0.016 0.0482 1
Echinococcus multilocularis aldo keto reductase 0.0025 0.004 0.0078
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0202 0.0427
Schistosoma mansoni hypothetical protein 0.0045 0.0105 0.022
Mycobacterium ulcerans lipase LipD 0.016 0.0482 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0018 0.0018 0.0033
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.004 0.007
Loa Loa (eye worm) matrix metalloproteinase 0.0043 0.0101 0.0099
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0014 0.0005 0.0004
Brugia malayi Thioredoxin reductase 0.0017 0.0015 0.0042
Echinococcus granulosus Protein patched homolog 1 0.002 0.0023 0.0038
Onchocerca volvulus Huntingtin homolog 0.0057 0.0146 0.0771
Echinococcus multilocularis sterol regulatory element binding protein 0.002 0.0023 0.0043
Giardia lamblia Cathepsin L precursor 0.0128 0.0377 0.313
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0069 0.0183 0.0384
Onchocerca volvulus 0.0583 0.1864 1
Trichomonas vaginalis esterase, putative 0.016 0.0482 0.2573
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Plasmodium falciparum serine repeat antigen 3 0.0128 0.0377 0.2022
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0185 0.0562 0.1859
Leishmania major calmodulin-like protein 0.0014 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0002
Brugia malayi Smad1 0.0027 0.0047 0.015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Echinococcus multilocularis 6 phosphofructokinase 0.0077 0.0212 0.0445
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0683 0.219 0.4674
Trichomonas vaginalis calmodulin, putative 0.0014 0.0004 0.0004
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0039 0.0085 0.0434
Entamoeba histolytica cysteine proteinase, putative 0.0583 0.1864 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0096 0.0094
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.002 0.0018
Echinococcus multilocularis programmed cell death protein 0.0014 0.0004 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.0313 0.098 0.3248
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Echinococcus granulosus short transient receptor potential channel 6 0.0038 0.0083 0.0153
Plasmodium falciparum serine repeat antigen 1 0.0128 0.0377 0.2022
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0025 0.004 0.0196
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.006 0.0156 0.0339
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0128 0.0377 0.0375
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0018 0.0018 0.0098
Brugia malayi 6-phosphofructokinase 0.0077 0.0212 0.0696
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0287 0.1525
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0021 0.0029 0.0054
Mycobacterium leprae Conserved hypothetical protein 0.0018 0.0016 0.0339
Onchocerca volvulus 0.0583 0.1864 1
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0683 0.219 0.4206
Schistosoma mansoni centrin-related 0.0014 0.0004 0.0004
Plasmodium vivax vivapain-2 0.0583 0.1864 1
Loa Loa (eye worm) hypothetical protein 0.0128 0.0377 0.0375
Schistosoma mansoni hypothetical protein 0.002 0.0024 0.0047
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0287 0.1525
Loa Loa (eye worm) calpain 5 0.0042 0.0097 0.0095
Leishmania major cathepsin L-like protease 0.0583 0.1864 0.4123
Onchocerca volvulus 0.0062 0.016 0.0848
Trypanosoma brucei calpain-like protein, putative 0.006 0.0156 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0004
Echinococcus granulosus transient receptor potential ion channel A 0.0055 0.014 0.0262
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.006 0.0156 0.0339
Echinococcus granulosus calcium uptake protein 1 0.0014 0.0006 0.0004
Trichomonas vaginalis calmodulin, putative 0.0014 0.0004 0.0004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0128 0.0377 0.0375
Trypanosoma brucei aldo-keto reductase, putative 0.0025 0.004 0.0081
Trypanosoma cruzi cysteine proteinase, putative 0.0313 0.098 0.2164
Mycobacterium leprae Probable lipase LipE 0.016 0.0482 1
Echinococcus granulosus centrin 2 0.0014 0.0004 0.0001
Echinococcus granulosus aldehyde reductase 0.0018 0.0016 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.016 0.0482 0.1026
Echinococcus multilocularis serotonin receptor 0.0069 0.0186 0.039
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.005 0.009
Brugia malayi Cathepsin L-like precursor 0.0399 0.1261 0.4183
Schistosoma mansoni neuronal calcium sensor 0.0014 0.0004 0.0004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.002 0.0058
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0014 0.0004 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0128 0.0377 0.2008
Entamoeba histolytica aldose reductase, putative 0.0025 0.004 0.0192
Brugia malayi Calmodulin-like protein 0.0014 0.0004 0.0006
Entamoeba histolytica cysteine proteinase 1, putative 0.0313 0.098 0.5246
Brugia malayi programmed cell death protein 6 0.0014 0.0004 0.0006
Trypanosoma brucei cysteine peptidase C (CPC) 0.0378 0.1192 0.2634
Loa Loa (eye worm) hypothetical protein 0.0128 0.0377 0.0375
Leishmania major calmodulin, putative 0.0014 0.0004 0.0002
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.002 0.0037
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0021
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0128 0.0377 0.2022
Giardia lamblia Cysteine protease 0.0128 0.0377 0.313
Echinococcus granulosus 6 phosphofructokinase 0.0077 0.0212 0.0401
Loa Loa (eye worm) phosphofructokinase 0.0077 0.0212 0.021
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0014 0.0004 0.0002
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0241 0.0745 0.1427
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0583 0.1864 1
Entamoeba histolytica aldose reductase, putative 0.0025 0.004 0.0192
Plasmodium falciparum cysteine proteinase falcipain 3 0.0583 0.1864 1
Trypanosoma cruzi I/6 autoantigen, putative 0.0014 0.0004 0.0002
Entamoeba histolytica cysteine protease, putative 0.0583 0.1864 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Echinococcus multilocularis neuronal calcium sensor 0.0014 0.0004 0.0002
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0036 0.0078 0.0419
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0024 0.0037 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0377 0.2008
Trypanosoma brucei calmodulin, putative 0.0014 0.0006 0.0005
Mycobacterium tuberculosis Probable dehydrogenase 0.0039 0.0086 0.0252
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0128 0.0377 0.0801
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0043 0.0101 0.0295
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0026 0.0044 0.0089
Schistosoma mansoni neuronal calcium sensor 0.0014 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0018 0.0018 0.008
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.0619 0.0617
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0128 0.0377 0.2022
Brugia malayi cathepsin L-like precursor 0.0399 0.1261 0.4183
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0047 0.0045
Leishmania major cathepsin L-like protease 0.1395 0.4516 1
Onchocerca volvulus 0.0025 0.004 0.0202
Schistosoma mansoni glutaminyl cyclase (M28 family) 0.0085 0.0238 0.0504
Toxoplasma gondii aldose reductase, putative 0.0025 0.004 0.0213
Brugia malayi PHD-finger family protein 0.0016 0.001 0.0025
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0583 0.1864 0.1862
Brugia malayi nicalin 0.0014 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0118 0.0344 0.0342
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.016 0.0482 0.1452
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0128 0.0377 0.313
Brugia malayi 6-phosphofructokinase 0.0077 0.0212 0.0696
Plasmodium vivax SET domain protein, putative 0.0029 0.0054 0.0292
Echinococcus multilocularis glutaminyl peptide cyclotransferase 0.0085 0.0238 0.0501
Toxoplasma gondii cathepsin B 0.0378 0.1192 0.6395
Brugia malayi Cathepsin L-like precursor 0.0583 0.1864 0.6185
Trypanosoma brucei antigen, putative 0.006 0.0156 0.0339
Leishmania major hypothetical protein, conserved 0.0014 0.0004 0.0002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0054 0.0111
Entamoeba histolytica phosphofructokinase, putative 0.0077 0.0212 0.1117
Brugia malayi cathepsin Z-like cysteine proteinase 0.0128 0.0377 0.1245
Brugia malayi Cathepsin L-like precursor 0.0185 0.0562 0.1859
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Trichomonas vaginalis glucosylceramidase, putative 0.0106 0.0305 0.162
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0036
Echinococcus granulosus peptidase Clp S14 family 0.0024 0.0037 0.0065
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0027 0.0146
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0014 0.0004 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Mycobacterium tuberculosis Probable lipase LipD 0.016 0.0482 0.1452
Mycobacterium ulcerans 6-phosphofructokinase 0.0077 0.0212 0.4352
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0036 0.0078 1
Entamoeba histolytica cysteine proteinase, putative 0.0583 0.1864 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0199 0.061 0.1299
Leishmania major aldo-keto reductase-like protein 0.0025 0.004 0.0081
Treponema pallidum sodium- and chloride- dependent transporter 0.0019 0.002 0.0928
Leishmania major cathepsin L-like protease 0.1395 0.4516 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0397 0.1255 0.1253
Brugia malayi hypothetical protein 0.0029 0.0053 0.0168
Trichomonas vaginalis calcium binding protein, putative 0.0014 0.0004 0.0004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.002 0.0105
Loa Loa (eye worm) hypothetical protein 0.0128 0.0377 0.0375
Schistosoma mansoni reticulocalbin 0.0014 0.0004 0.0004
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0063 0.0165 0.054
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0459 0.245
Leishmania major cathepsin L-like protease 0.0583 0.1864 0.4123
Onchocerca volvulus 0.0019 0.002 0.0094
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0583 0.1864 1
Loa Loa (eye worm) hypothetical protein 0.0241 0.0745 0.0743
Loa Loa (eye worm) hypothetical protein 0.0045 0.0104 0.0102
Schistosoma mansoni hypothetical protein 0.0062 0.016 0.0337
Schistosoma mansoni hypothetical protein 0.0143 0.0425 0.0904
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.006 0.0156 0.0339
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0021 0.0029 0.0048
Entamoeba histolytica calpain large subunit domain III containing protein 0.0042 0.0097 0.0499
Loa Loa (eye worm) hypothetical protein 0.0118 0.0344 0.0342
Loa Loa (eye worm) hypothetical protein 0.0123 0.036 0.0358
Mycobacterium tuberculosis Conserved protein 0.016 0.0482 0.1452
Onchocerca volvulus Matrilysin homolog 0.0141 0.0421 0.225
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0128 0.0377 0.2008
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0025 0.004 0.0081
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0123 0.036 0.0764
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0128 0.0377 0.313
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0021 0.0027 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0128 0.0377 0.1245
Entamoeba histolytica hypothetical protein 0.0069 0.0183 0.0963
Schistosoma mansoni neuronal calcium sensor 0.0014 0.0004 0.0004
Loa Loa (eye worm) Smad1 0.0027 0.0047 0.0045
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.006 0.0156 0.0339
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0046 0.0109 0.0564
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Plasmodium vivax calpain, putative 0.006 0.0156 0.0838
Brugia malayi hypothetical protein 0.0069 0.0183 0.0601
Trypanosoma cruzi cysteine peptidase, putative 0.1395 0.4516 1
Brugia malayi TAR-binding protein 0.0074 0.0202 0.0664
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0027 0.0128
Trypanosoma brucei kinesin, putative 0.0042 0.0097 0.0207
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0128 0.0377 0.2022
Onchocerca volvulus 0.0025 0.004 0.0202
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0313 0.098 0.2089
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0199 0.061 0.0608
Trichomonas vaginalis phosphofructokinase, putative 0.0077 0.0212 0.112
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0123 0.036 0.0764
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.002 0.0037
Trypanosoma brucei prostaglandin f synthase 0.0025 0.004 0.0081
Entamoeba histolytica cysteine proteinase, putative 0.0313 0.098 0.5246
Schistosoma mansoni biogenic amine (5HT) receptor 0.0384 0.1213 0.2587
Echinococcus multilocularis thioredoxin glutathione reductase 0.0017 0.0016 0.0026
Trypanosoma brucei calmodulin, putative 0.0014 0.0004 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0199 0.061 0.1299
Schistosoma mansoni transient receptor potential channel 4 0.0057 0.0146 0.0307
Mycobacterium tuberculosis Probable oxidoreductase 0.0043 0.0101 0.0295
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0053 0.0132 0.0389
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0377 0.2008
Brugia malayi calpain D 0.0018 0.0018 0.0054
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0027 0.1296
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0018 0.0033
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Loa Loa (eye worm) fibroinase 0.0583 0.1864 0.1862
Schistosoma mansoni dopamine-beta-monooxygenase 0.0128 0.0376 0.08
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.016 0.0482 0.048
Trichomonas vaginalis calmodulin, putative 0.0014 0.0004 0.0004
Trichomonas vaginalis calmodulin, putative 0.0014 0.0004 0.0004
Schistosoma mansoni calpain-2 (C02 family) 0.0018 0.0018 0.0035
Echinococcus multilocularis calmodulin 0.0014 0.0004 0.0002
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Leishmania major prostaglandin f synthase, putative 0.0025 0.004 0.0081
Giardia lamblia Cathepsin L precursor 0.0128 0.0377 0.313
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0077 0.0157
Echinococcus multilocularis aldo keto reductase 0.0025 0.004 0.0078
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Echinococcus multilocularis adam 17 protease 0.1446 0.4683 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.004 0.0038
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0044 0.0103 0.0101
Onchocerca volvulus Cathepsin F homolog 0.0583 0.1864 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0378 0.1192 0.6389
Loa Loa (eye worm) hypothetical protein 0.0123 0.036 0.0358
Trypanosoma cruzi aldo-keto reductase 0.0025 0.004 0.0081
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0025 0.004 0.0081
Entamoeba histolytica cysteine proteinase, putative 0.0313 0.098 0.5246
Trichomonas vaginalis phosphofructokinase, putative 0.0077 0.0212 0.112
Loa Loa (eye worm) hypothetical protein 0.0118 0.0344 0.0342
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0636 0.2035 0.6755
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0583 0.1864 1
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0459 0.245
Trypanosoma cruzi cysteine proteinase, putative 0.0313 0.098 0.2164
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.006 0.0156 0.0339
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.006 0.0156 0.0339
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0077 0.0142
Echinococcus multilocularis calpain family protein 1, d 0.0118 0.0344 0.0728
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0043 0.0101 0.2087
Loa Loa (eye worm) glutaminase 2 0.0121 0.0355 0.0353
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Mycobacterium tuberculosis Probable conserved lipoprotein 0.016 0.0482 0.1452
Onchocerca volvulus 0.0019 0.002 0.0094
Giardia lamblia Cathepsin L precursor 0.0128 0.0377 0.313
Brugia malayi ADAMTS-like protease 0.0118 0.0344 0.1137
Entamoeba histolytica cysteine protease, putative 0.0128 0.0377 0.2005
Toxoplasma gondii cathepsin CPC1 0.0128 0.0377 0.2022
Brugia malayi Bromodomain containing protein 0.0023 0.0033 0.0103
Trichomonas vaginalis phosphofructokinase, putative 0.0077 0.0212 0.112
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Plasmodium falciparum cysteine proteinase falcipain 1 0.0313 0.098 0.5257
Giardia lamblia Cathepsin B precursor 0.0378 0.1192 1
Schistosoma mansoni cathepsin F (C01 family) 0.0399 0.1261 0.269
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0128 0.0377 0.2008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0054 0.0112
Trypanosoma brucei protein I/6 0.0014 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0399 0.1261 0.1259
Loa Loa (eye worm) hypothetical protein 0.0128 0.0377 0.0375
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0002
Brugia malayi Probable ClpP-like protease 0.0036 0.0078 0.0253
Schistosoma mansoni neuronal calcium sensor 0.0014 0.0004 0.0004
Brugia malayi Fli-1 protein 0.0134 0.0396 0.1308
Trichomonas vaginalis aldo/keto reductase, putative 0.0025 0.004 0.0196
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.004 0.007
Echinococcus multilocularis cathepsin L cysteine protease 0.0583 0.1864 0.3976
Brugia malayi Hemopexin family protein 0.0062 0.016 0.0525
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0683 0.219 0.4672
Loa Loa (eye worm) hypothetical protein 0.0185 0.0562 0.056
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0405 0.1283 0.2735
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0377 0.2008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0143 0.0425 0.0811
Brugia malayi Papain family cysteine protease containing protein 0.0128 0.0377 0.1245
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0024 0.0037 0.0769
Entamoeba histolytica cysteine protease, putative 0.0128 0.0377 0.2005
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0001
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.002 0.0037
Schistosoma mansoni bromodomain containing protein 0.0038 0.0084 0.0175
Plasmodium falciparum serine repeat antigen 8 0.0128 0.0377 0.2022
Trichomonas vaginalis calpain, putative 0.0018 0.0018 0.008
Brugia malayi Peptidase family M28 containing protein 0.0085 0.0238 0.0783
Loa Loa (eye worm) hypothetical protein 0.01 0.0285 0.0283
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0021 0.0027 0.0128
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.002 0.0024 0.004
Loa Loa (eye worm) cathepsin B 0.0378 0.1192 0.119
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0004
Entamoeba histolytica aldose reductase, putative 0.0025 0.004 0.0192
Echinococcus granulosus calpain 7 C02 family 0.006 0.0156 0.0294
Onchocerca volvulus 0.0014 0.0003 0.0007
Entamoeba histolytica phosphofructokinase, putative 0.0077 0.0212 0.1117
Plasmodium vivax ataxin-2 like protein, putative 0.0045 0.0104 0.056
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.002 0.0037
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.004 0.007
Echinococcus multilocularis centrin 2 0.0014 0.0004 0.0002
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0036 0.0078 0.0419
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0027 0.0128
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0027 0.0146
Trypanosoma brucei calpain, putative 0.0018 0.0018 0.0033
Trypanosoma brucei Calpain-like protein 2 0.0018 0.0018 0.0033
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0128 0.0377 0.1245
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0377 0.2008
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0014 0.0004 0.0002
Brugia malayi Matrixin family protein 0.0043 0.0101 0.0328
Mycobacterium tuberculosis Probable hydrolase 0.016 0.0482 0.1452
Mycobacterium tuberculosis Conserved protein 0.016 0.0482 0.1452
Echinococcus multilocularis calpain A 0.0174 0.0529 0.1123
Entamoeba histolytica hypothetical protein 0.0069 0.0183 0.0963
Echinococcus granulosus aldo keto reductase 0.0025 0.004 0.007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0128 0.0377 0.0801
Echinococcus multilocularis EF hand domain containing family member A2 0.0014 0.0004 0.0002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.002 0.0058
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.048
Schistosoma mansoni cathepsin F (C01 family) 0.0583 0.1864 0.3978
Loa Loa (eye worm) fli-1 protein 0.0134 0.0396 0.0394
Trypanosoma brucei hypothetical protein 0.0018 0.0018 0.0033
Brugia malayi calpain family protein 1 0.016 0.0482 0.1594
Echinococcus multilocularis smad 0.0027 0.0047 0.0094
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0202 0.0427
Trypanosoma brucei hypothetical protein, conserved 0.016 0.0482 0.1061
Plasmodium falciparum serine repeat antigen 5 0.0128 0.0377 0.2022
Schistosoma mansoni transient receptor potential channel 0.0038 0.0083 0.0172
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0018 0.0018 0.008
Mycobacterium tuberculosis Probable lipase LipE 0.016 0.0482 0.1452
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0583 0.1864 0.358
Echinococcus granulosus microtubule associated protein 2 0.0639 0.2048 0.3934
Leishmania major kinesin, putative 0.0042 0.0097 0.0207
Brugia malayi Cathepsin L-like precursor 0.0583 0.1864 0.6185
Leishmania major calcineurin B subunit, putative 0.0014 0.0004 0.0002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0327 0.1028 0.2191
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0583 0.1864 1
Brugia malayi Pre-SET motif family protein 0.0202 0.0619 0.2051
Trypanosoma brucei Calpain-like protein 1.1 0.0018 0.0018 0.0033
Echinococcus granulosus tm gpcr rhodopsin 0.0405 0.1283 0.2462
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0039 0.0088 0.0182
Echinococcus granulosus cathepsin l1 0.0399 0.1261 0.242
Brugia malayi hypothetical protein 0.0219 0.0675 0.2234
Giardia lamblia Hypothetical protein 0.0128 0.0377 0.313
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0039 0.0085 0.0434
Mycobacterium tuberculosis Conserved protein 0.016 0.0482 0.1452
Leishmania major hypothetical protein, conserved 0.0018 0.0018 0.0033
Leishmania major calpain family cysteine protease-like protein 0.0018 0.0018 0.0033
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Loa Loa (eye worm) ctsf protein 0.0583 0.1864 0.1862
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0935 0.3012 0.6431
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0123 0.036 0.0686
Schistosoma mansoni hypothetical protein 0.0143 0.0425 0.0904
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.006 0.0156 0.0339
Echinococcus granulosus adam 17 protease 0.1605 0.5201 1
Schistosoma mansoni hypothetical protein 0.0019 0.0021 0.004
Plasmodium falciparum amino acid transporter, putative 0.0019 0.002 0.0105
Echinococcus multilocularis survival motor neuron protein 1 0.0219 0.0675 0.1435
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0039 0.0086 0.0252
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0027 0.0146
Schistosoma mansoni patched 1 0.002 0.0023 0.0045
Trypanosoma cruzi PAB1-binding protein , putative 0.0045 0.0104 0.0224
Plasmodium vivax unspecified product 0.0185 0.0562 0.3014
Schistosoma mansoni cathepsin S (C01 family) 0.0128 0.0377 0.0801
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0174 0.0527 0.1008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0074
Onchocerca volvulus 0.0399 0.1261 0.6762
Brugia malayi Bromodomain containing protein 0.0045 0.0107 0.0347
Echinococcus granulosus calumenin 0.0014 0.0006 0.0004
Schistosoma mansoni centrin 0.0014 0.0004 0.0004
Echinococcus granulosus biogenic amine 5HT receptor 0.0384 0.1213 0.2327
Onchocerca volvulus Glucosylceramidase homolog 0.01 0.0287 0.1531
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0039 0.0086 0.0252
Schistosoma mansoni calpain-7 (C02 family) 0.006 0.0156 0.0329
Brugia malayi FXNA 0.0014 0.0003 0.0004
Onchocerca volvulus 0.0014 0.0006 0.0019
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0935 0.3012 0.6668
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0203 0.0622 0.1323
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.002 0.0031
Giardia lamblia Aldose reductase 0.0025 0.004 0.0288
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.002 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0128 0.0377 0.2008
Brugia malayi RNA binding protein 0.0074 0.0202 0.0664
Schistosoma mansoni sodium-dependent amino acid transporter 0.0019 0.002 0.0037
Leishmania major protein kinase, putative 0.0014 0.0004 0.0002
Schistosoma mansoni hypothetical protein 0.0019 0.0021 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.0313 0.098 0.2164
Echinococcus granulosus calpain A 0.0174 0.0529 0.1011
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.048
Echinococcus granulosus glutaminyl peptide cyclotransferase 0.0085 0.0238 0.0451
Plasmodium falciparum thioredoxin reductase 0.0017 0.0015 0.0079
Brugia malayi cathepsin L precursor 0.0128 0.0377 0.1245
Brugia malayi CHE-14 protein 0.002 0.0023 0.007
Plasmodium vivax unspecified product 0.0313 0.098 0.5257
Toxoplasma gondii cathepsin CPC2 0.0128 0.0377 0.2022
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0018 0.0018 0.0033
Onchocerca volvulus 0.0025 0.004 0.0202
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0199 0.061 0.1296
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0202 0.0427
Giardia lamblia Cathepsin B precursor 0.0378 0.1192 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0004
Schistosoma mansoni calmodulin 0.0014 0.0004 0.0004
Trichomonas vaginalis penicillin-binding protein, putative 0.016 0.0482 0.2573
Onchocerca volvulus 0.0583 0.1864 1
Trichomonas vaginalis glutaminase, putative 0.0121 0.0355 0.189
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0018
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0021 0.0029 0.0054
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0123 0.036 0.0764
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Brugia malayi Disintegrin family protein 0.0197 0.0603 0.1996
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0077 0.0212 0.0632
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0054 0.0109
Loa Loa (eye worm) hypothetical protein 0.0935 0.3012 0.3011
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.004 0.0196
Brugia malayi Ets-domain containing protein 0.0044 0.0103 0.0335
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0143 0.0425 0.1405
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0027 0.1296
Trichomonas vaginalis calmodulin, putative 0.0014 0.0006 0.0012
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0199 0.061 0.2019
Echinococcus granulosus disintegrin and metalloproteinase 0.0197 0.0603 0.1154
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0143 0.0425 0.0901
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Echinococcus granulosus calpain 0.006 0.0156 0.0294
Echinococcus multilocularis geminin 0.0365 0.1152 0.2455
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Entamoeba histolytica cysteine protease, putative 0.0128 0.0377 0.2005
Brugia malayi hypothetical protein 0.0045 0.0104 0.034
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0036 0.0078 0.5
Leishmania major calmodulin, putative 0.0014 0.0004 0.0002
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0014 0.0004 0.0004
Schistosoma mansoni rab 0.0014 0.0004 0.0004
Toxoplasma gondii cathepsin CPL 0.0583 0.1864 1
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0287 0.1525
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Plasmodium falciparum serine repeat antigen 2 0.0128 0.0377 0.2022
Trichomonas vaginalis D-aminoacylase, putative 0.016 0.0482 0.2573
Echinococcus granulosus calpain 5 0.006 0.0156 0.0294
Entamoeba histolytica hypothetical protein 0.0069 0.0183 0.0963
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0128 0.0377 0.2022
Loa Loa (eye worm) hypothetical protein 0.0057 0.0146 0.0144
Loa Loa (eye worm) RNA binding protein 0.0074 0.0202 0.02
Entamoeba histolytica cysteine protease, putative 0.0128 0.0377 0.2005
Mycobacterium ulcerans hydrolase 0.0053 0.0132 0.2681
Brugia malayi cathepsin B-like cysteine proteinase 0.0935 0.3012 1
Echinococcus multilocularis disintegrin and metalloproteinase 0.0197 0.0603 0.1281
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0018 0.0033
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0128 0.0377 0.2005
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0019 0.002 0.0058
Trypanosoma cruzi major cysteine proteinase, putative 0.094 0.3029 0.6705
Echinococcus multilocularis short transient receptor potential channel 6 0.0038 0.0083 0.0169
Loa Loa (eye worm) hypothetical protein 0.0128 0.0377 0.0375
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Echinococcus granulosus geminin 0.0365 0.1152 0.221
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.002 0.0037
Mycobacterium ulcerans oxidoreductase 0.0025 0.004 0.0761
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Schistosoma mansoni aldo-keto reductase 0.0025 0.004 0.008
Echinococcus granulosus EF HAND 1 calcium binding site 0.0014 0.0004 0.0001
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0123 0.036 0.0762
Echinococcus granulosus transient receptor potential gamma protein 0.0057 0.0146 0.0274
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0018
Echinococcus granulosus EF hand domain containing family member A2 0.0014 0.0004 0.0001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0128 0.0377 0.0375
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0185 0.0562 0.056
Leishmania major cathepsin L-like protease 0.0583 0.1864 0.4123
Echinococcus multilocularis aldo keto reductase 0.0025 0.004 0.0078
Loa Loa (eye worm) hypothetical protein 0.0053 0.0132 0.013
Echinococcus multilocularis calpain 5 0.006 0.0156 0.0327
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0054 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0377 0.2008
Echinococcus granulosus cathepsin L 0.0128 0.0377 0.0719
Loa Loa (eye worm) oxidoreductase 0.0025 0.004 0.0038
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0053 0.0132 0.0431
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.004 0.007
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0021 0.0027 0.0146
Echinococcus granulosus cathepsin l1 0.0583 0.1864 0.358
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0036 0.0078 0.1562
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0935 0.3012 0.6431
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.004 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0128 0.0377 0.2008
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0974 0.3139 0.6702
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.002
Onchocerca volvulus 0.0583 0.1864 1
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0241 0.0745 0.1585
Leishmania major cathepsin L-like protease 0.1395 0.4516 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0025 0.004 0.0125
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0159 0.0477 0.0911
Toxoplasma gondii calcium-dependent protein kinase 0.0014 0.0006 0.003
Toxoplasma gondii centrin, putative 0.0014 0.0004 0.0022
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0159 0.0477 0.1015
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0174 0.0527 0.1122
Loa Loa (eye worm) hypothetical protein 0.0399 0.1261 0.1259
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0106 0.0305 0.162
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0128 0.0377 0.2008
Echinococcus multilocularis cathepsin L 0.0128 0.0377 0.0798
Trypanosoma cruzi hypothetical protein, conserved 0.016 0.0482 0.1061
Schistosoma mansoni hypothetical protein 0.0069 0.0183 0.0387
Echinococcus multilocularis cathepsin b 0.0935 0.3012 0.643
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0077 0.0212 1
Schistosoma mansoni hypothetical protein 0.0365 0.1152 0.2457
Schistosoma mansoni aldo-keto reductase 0.0025 0.004 0.008
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0175 0.0532 0.053
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0025 0.004 0.0825
Giardia lamblia Cathepsin L-like protease 0.0128 0.0377 0.313
Trypanosoma cruzi centrin, putative 0.0014 0.0004 0.0002
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0018 0.0018 0.0033
Onchocerca volvulus 0.0019 0.002 0.0094
Trichomonas vaginalis hypothetical protein 0.0018 0.0018 0.008
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.004 0.007
Onchocerca volvulus 0.0583 0.1864 1
Schistosoma mansoni Smad4 0.0027 0.0047 0.0096
Echinococcus multilocularis neurocalcin 0.0014 0.0004 0.0002
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0027 0.0047 0.0096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0583 0.1864 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Trypanosoma cruzi centrin-3 0.0014 0.0004 0.0002
Leishmania major trypanothione reductase 0.0017 0.0015 0.0025
Echinococcus granulosus cathepsin L 0.0313 0.098 0.1879
Echinococcus multilocularis cpg binding protein 0.0015 0.0008 0.0011
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0128 0.0377 0.2022
Leishmania major calpain protease-like protein 0.0018 0.0018 0.0033
Onchocerca volvulus 0.0025 0.004 0.0202
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0043 0.0101 0.0295
Leishmania major i/6 autoantigen-like protein 0.0014 0.0004 0.0002
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0128 0.0377 0.0801
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.048
Schistosoma mansoni cathepsin C 0.0128 0.0377 0.0801
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0036 0.0078 0.0419
Toxoplasma gondii preprocathepsin c precursor, putative 0.0128 0.0377 0.2022
Brugia malayi Papain family cysteine protease containing protein 0.0128 0.0377 0.1245
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0128 0.0377 0.2005
Plasmodium vivax hypothetical protein, conserved 0.0019 0.002 0.0105
Loa Loa (eye worm) hypothetical protein 0.0308 0.0966 0.0964
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0036 0.0078 0.016
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0202 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Onchocerca volvulus 0.0025 0.004 0.0202
Echinococcus granulosus programmed cell death protein 0.0014 0.0004 0.0001
Trypanosoma cruzi calmodulin, putative 0.0014 0.0004 0.0002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.006 0.0156 0.0339
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0128 0.0377 0.2022
Brugia malayi Matrixin family protein 0.0043 0.0101 0.0328
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0036 0.0078 0.0419
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.002 0.0037
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.004 0.007
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0018 0.0018 0.0033
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0077 0.0212 0.0462
Loa Loa (eye worm) hypothetical protein 0.0178 0.054 0.0538
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0583 0.1864 0.1862
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0128 0.0377 0.0801
Schistosoma mansoni hypothetical protein 0.0143 0.0425 0.0904
Echinococcus multilocularis serotonin transporter 0.0019 0.002 0.0035
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0077 0.0212 0.0462
Entamoeba histolytica cysteine proteinase, putative 0.0313 0.098 0.5246
Loa Loa (eye worm) hypothetical protein 0.0399 0.1261 0.1259
Schistosoma mansoni microtubule-associated protein tau 0.0639 0.2048 0.4371
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0459 0.245
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0128 0.0377 0.2022
Echinococcus multilocularis cathepsin L cysteine protease 0.0583 0.1864 0.3976
Giardia lamblia Cysteine protease 0.0128 0.0377 0.313
Echinococcus granulosus cathepsin l cysteine peptidase 0.0583 0.1864 0.358
Entamoeba histolytica cysteine protease, putative 0.0128 0.0377 0.2005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0313 0.098 0.5248
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0018 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0287 0.1525
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.004 0.0078
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.002 0.0031
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0077 0.0212 0.4391
Loa Loa (eye worm) calpain D 0.0018 0.0018 0.0016
Trypanosoma brucei cysteine peptidase, putative 0.0018 0.0018 0.0033
Trypanosoma cruzi major cysteine proteinase, putative 0.0128 0.0377 0.0828
Toxoplasma gondii EF hand domain-containing protein 0.0014 0.0004 0.0022
Echinococcus multilocularis mothers against decapentaplegic 5 0.0027 0.0047 0.0094
Echinococcus granulosus survival motor neuron protein 1 0.0219 0.0675 0.1292
Loa Loa (eye worm) oxidoreductase 0.0025 0.004 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0199 0.061 0.1296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Onchocerca volvulus Fxna peptidase homolog 0.0014 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0185 0.0562 0.056
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0018 0.0033
Schistosoma mansoni 6-phosphofructokinase 0.0077 0.0212 0.0448
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0018
Loa Loa (eye worm) glutathione reductase 0.0017 0.0015 0.0013
Echinococcus multilocularis GA binding protein alpha chain 0.0044 0.0103 0.0213
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0935 0.3012 0.6431
Echinococcus multilocularis protein dispatched 1 0.0022 0.0032 0.0062
Plasmodium falciparum calpain 0.0018 0.0018 0.0098
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Mycobacterium ulcerans hypothetical protein 0.016 0.0482 1
Loa Loa (eye worm) hypothetical protein 0.0128 0.0377 0.0375
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0018 0.0018 0.0033
Schistosoma mansoni cpg binding protein 0.0015 0.0008 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Brugia malayi MH1 domain containing protein 0.0015 0.0008 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0313 0.098 0.2164
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Schistosoma mansoni Mername-AA248 (C02 family) 0.006 0.0156 0.0329
Leishmania major cysteine peptidase A (CPA) 0.0583 0.1864 0.4123
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.002 0.0035
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0036 0.0078 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0018 0.0018 0.008
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Plasmodium vivax thioredoxin reductase, putative 0.0017 0.0015 0.0079
Trypanosoma cruzi calmodulin, putative 0.0014 0.0004 0.0002
Echinococcus multilocularis adam 0.0277 0.0862 0.1836
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.016 0.0482 0.1595
Toxoplasma gondii hypothetical protein 0.0014 0.0003 0.0018
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.002 0.0035
Trypanosoma cruzi conserved protein 0.0018 0.0018 0.0033
Schistosoma mansoni hypothetical protein 0.0143 0.0425 0.0904
Brugia malayi angiogenesis inhibito 0.0118 0.0344 0.1137
Echinococcus granulosus calmodulin 0.0014 0.0004 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.016 0.0482 0.2573
Entamoeba histolytica cysteine proteinase 2 0.0313 0.098 0.5246
Trichomonas vaginalis calcium binding protein, putative 0.0014 0.0004 0.0004
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0036 0.0078 0.0144
Schistosoma mansoni mitochondrial solute carrier 0.0014 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0313 0.098 0.5248
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0128 0.0377 0.0801
Brugia malayi hypothetical protein 0.0019 0.002 0.0058
Entamoeba histolytica hypothetical protein, conserved 0.0014 0.0006 0.0008
Entamoeba histolytica calpain family cysteine protease, putative 0.0018 0.0018 0.0076
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0019 0.002 0.0035
Trichomonas vaginalis calpain, putative 0.0018 0.0018 0.008
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0128 0.0377 0.0801
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0024 0.0037 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.006 0.0156 0.0339
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0027 0.0128
Trichomonas vaginalis aldo/keto reductase, putative 0.0025 0.004 0.0196
Echinococcus granulosus calbindin 32 0.0014 0.0006 0.0004
Echinococcus granulosus expressed conserved protein 0.0043 0.01 0.0186
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0015 0.0025
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Loa Loa (eye worm) oxidoreductase 0.0025 0.004 0.0038
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0025 0.004 0.0196
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0021 0.0027 0.0182
Onchocerca volvulus 0.0025 0.004 0.0202
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0128 0.0377 0.2022
Schistosoma mansoni glutaminase 0.0121 0.0355 0.0754
Trypanosoma brucei mitochondrial calcium uptake 1 0.0014 0.0004 0.0002
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0128 0.0377 0.313
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0384 0.1213 0.2585
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0287 0.1525
Echinococcus granulosus thioredoxin glutathione reductase 0.0017 0.0016 0.0024
Trypanosoma brucei calpain-like protein, putative 0.006 0.0156 0.0339
Trichomonas vaginalis calpain, putative 0.0018 0.0018 0.008
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.002 0.0037
Giardia lamblia Cathepsin L precursor 0.0128 0.0377 0.313
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0107
Schistosoma mansoni nicalin (M28 family) 0.0014 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0308 0.0966 0.2059
Onchocerca volvulus 0.016 0.0482 0.2578
Leishmania major cathepsin L-like protease 0.0583 0.1864 0.4123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0583 0.1864 1
Schistosoma mansoni cpg binding protein 0.0015 0.0008 0.0013
Leishmania major hypothetical protein, conserved 0.0045 0.0104 0.0224
Schistosoma mansoni smad 0.0027 0.0047 0.0096
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0014 0.0004 0.0002
Leishmania major ATP-dependent phosphofructokinase 0.0077 0.0212 0.0462
Trichomonas vaginalis calmodulin, putative 0.0014 0.0004 0.0004
Trichomonas vaginalis calcineurin B subunit, putative 0.0014 0.0004 0.0004
Loa Loa (eye worm) calpain 0.006 0.0156 0.0154
Echinococcus granulosus TGF beta signal transducer SmadC 0.0027 0.0047 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0399 0.1261 0.676
Onchocerca volvulus 0.01 0.0285 0.1518
Entamoeba histolytica protein kinase, putative 0.0042 0.0097 0.0499
Trypanosoma cruzi cruzipain precursor, putative 0.0185 0.0562 0.1238
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.048
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0459 0.245
Brugia malayi Niemann-Pick C1 protein precursor 0.0046 0.0109 0.0355
Schistosoma mansoni cathepsin F (C01 family) 0.0583 0.1864 0.3978
Plasmodium vivax centrin-1, putative 0.0014 0.0004 0.0022
Echinococcus granulosus sterol regulatory element binding protein 0.002 0.0023 0.0038
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0241 0.0745 0.2467
Brugia malayi Cathepsin L-like precursor 0.0583 0.1864 0.6185
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0089 0.0248 0.0526
Schistosoma mansoni hypothetical protein 0.0365 0.1152 0.2457
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0001
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.002 0.0037
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0027 0.0146
Echinococcus granulosus adam 0.0277 0.0862 0.1653
Plasmodium vivax vivapain-1 0.0313 0.098 0.5257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0583 0.1864 1
Brugia malayi Cathepsin L-like precursor 0.0583 0.1864 0.6185
Trichomonas vaginalis calcium binding protein, putative 0.0014 0.0004 0.0004
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0583 0.1864 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0583 0.1864 1
Trypanosoma brucei I/6 autoantigen 0.0014 0.0004 0.0002
Entamoeba histolytica hypothetical protein 0.0128 0.0377 0.2005
Giardia lamblia Encystation-specific protease 0.0128 0.0377 0.313
Echinococcus multilocularis calmodulin 0.0014 0.0004 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1395 0.4516 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0238 0.0236
Trichomonas vaginalis D-aminoacylase, putative 0.016 0.0482 0.2573
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Echinococcus granulosus cathepsin b 0.0935 0.3012 0.5789
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Schistosoma mansoni calpain C (C02 family) 0.006 0.0156 0.0329
Leishmania major centrin, putative 0.0014 0.0004 0.0002
Echinococcus multilocularis transient receptor potential ion channel A 0.0055 0.014 0.0292
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0313 0.098 0.2089
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.0042
Onchocerca volvulus Glutaminyl cyclase homolog 0.0085 0.0238 0.1267
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1211 0.3913 0.8664
Loa Loa (eye worm) hypothetical protein 0.0185 0.0562 0.056
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0199 0.061 0.1167
Loa Loa (eye worm) 6-phosphofructokinase 0.0077 0.0212 0.021
Brugia malayi Cathepsin L-like precursor 0.0583 0.1864 0.6185
Schistosoma mansoni biogenic amine (5HT) receptor 0.0069 0.0186 0.0392
Plasmodium falciparum centrin-1 0.0014 0.0004 0.0022
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.016 0.0482 0.1026
Onchocerca volvulus 0.0014 0.0004 0.001
Schistosoma mansoni hypothetical protein 0.0018 0.0018 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0399 0.1261 0.676
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0313 0.098 0.2164
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Schistosoma mansoni transcription factor LCR-F1 0.0069 0.0183 0.0387
Trypanosoma brucei PAB1-binding protein , putative 0.0045 0.0104 0.0224
Echinococcus multilocularis programmed cell death protein 0.0014 0.0004 0.0002
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0025 0.004 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0583 0.1864 1
Entamoeba histolytica cysteine protease, putative 0.0313 0.098 0.5246
Giardia lamblia Cathepsin B precursor 0.0128 0.0377 0.313
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0018
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0277 0.0862 0.1838
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.016 0.0482 1
Loa Loa (eye worm) calmodulin-like protein 0.0014 0.0004 0.0002
Schistosoma mansoni survival motor neuron protein 0.0045 0.0105 0.022
Loa Loa (eye worm) hypothetical protein 0.0583 0.1864 0.1862
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0018 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0377 0.2008
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0018 0.0018 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0377 0.2008
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.002 0.0037
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0018 0.0033
Echinococcus multilocularis GPCR, family 2 0.0143 0.0425 0.0901
Echinococcus granulosus biogenic amine 5HT receptor 0.0069 0.0186 0.0351
Echinococcus multilocularis serotonin receptor 0.0069 0.0186 0.039

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 7.42 Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assay ChEMBL. 21134748

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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