Detailed information for compound 1802280

Basic information

Technical information
  • TDR Targets ID: 1802280
  • Name: (1S,3aS,3bS,9aR,9bS,11aS)-9a,11a-dimethyl-1-( 3-methylbutanoyl)-1,2,3,3a,3b,4,5,8,9,9b,10,1 1-dodecahydrocyclopenta[i]phenanthridin-7-one
  • MW: 357.53 | Formula: C23H35NO2
  • H donors: 1 H acceptors: 2 LogP: 4.62 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CC(=O)[C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CNC2=CC(=O)CC[C@]12C)C
  • InChi: 1S/C23H35NO2/c1-14(2)11-20(26)19-6-5-17-16-13-24-21-12-15(25)7-9-23(21,4)18(16)8-10-22(17,19)3/h12,14,16-19,24H,5-11,13H2,1-4H3/t16-,17-,18-,19+,22-,23+/m0/s1
  • InChiKey: XUEIZFLCTVGAEF-XEAGOBSMSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (1S,3aS,3bS,9aR,9bS,11aS)-9a,11a-dimethyl-1-(3-methyl-1-oxobutyl)-1,2,3,3a,3b,4,5,8,9,9b,10,11-dodecahydrocyclopenta[i]phenanthridin-7-one
  • (1S,3aS,3bS,9aR,9bS,11aS)-1-isovaleryl-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9b,10,11-dodecahydrocyclopenta[i]phenanthridin-7-one

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania braziliensis 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein Get druggable targets OG5_128852 All targets in OG5_128852
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative Get druggable targets OG5_128852 All targets in OG5_128852
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128852 All targets in OG5_128852
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase Get druggable targets OG5_128852 All targets in OG5_128852
Leishmania donovani 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein Get druggable targets OG5_128852 All targets in OG5_128852
Leishmania infantum 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein Get druggable targets OG5_128852 All targets in OG5_128852
Trypanosoma brucei gambiense 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative Get druggable targets OG5_128852 All targets in OG5_128852
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative Get druggable targets OG5_128852 All targets in OG5_128852
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein Get druggable targets OG5_128852 All targets in OG5_128852
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative Get druggable targets OG5_128852 All targets in OG5_128852
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_128852 All targets in OG5_128852
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative Get druggable targets OG5_128852 All targets in OG5_128852
Leishmania mexicana 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein Get druggable targets OG5_128852 All targets in OG5_128852
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative Get druggable targets OG5_128852 All targets in OG5_128852
Entamoeba histolytica steroid 5-alpha reductase, putative Get druggable targets OG5_128852 All targets in OG5_128852
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative Get druggable targets OG5_128852 All targets in OG5_128852
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Get druggable targets OG5_128852 All targets in OG5_128852
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Synaptic glycoprotein SC2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 254 aa 208 aa 28.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus granulosus o acyltransferase membrane bound domain 0.0094 0.0685 0.0904
Echinococcus multilocularis peregrin 0.0008 0.0005 0.0002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Schistosoma mansoni axis inhibition protein axin 0.0021 0.011 0.0141
Brugia malayi DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide 0.0014 0.0052 0.0103
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0094 0.0685 0.0904
Trypanosoma cruzi DNA-directed RNA polymerase III, putative 0.0014 0.0052 0.0244
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0094 0.0685 0.0904
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0027 0.0152 0.0263
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0094 0.0685 0.1216
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0005 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0005 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0155 0.015
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0241 0.0315
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0094 0.0685 0.0904
Mycobacterium leprae PROBABLE CHOLESTEROL DEHYDROGENASE 0.0027 0.0157 0.0738
Echinococcus granulosus protein kinase C binding protein 1 0.0008 0.0005 0.0002
Echinococcus granulosus geminin 0.0177 0.1343 0.1776
Loa Loa (eye worm) BRM protein 0.0008 0.0005 0.0002
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.011 0.0141
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0008 0.0005 0.0002
Entamoeba histolytica vacuolar protein sorting 26 0.0094 0.0685 0.4763
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.008 0.0571 0.2746
Mycobacterium tuberculosis Probable sulfatase 0.001 0.0017 0.0013
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0031 0.0036
Schistosoma mansoni zinc finger protein 0.001 0.002 0.0022
Schistosoma mansoni GMP synthetase 0.0032 0.0194 0.0252
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Loa Loa (eye worm) hypothetical protein 0.0094 0.0685 0.0904
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0155 0.0783
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0206 0.036
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.011 0.0226
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0094 0.0685 0.0904
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Brugia malayi polybromodomain protein 0.0008 0.0005 0.0004
Brugia malayi MBOAT family protein 0.0094 0.0685 0.1446
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0054 0.0254
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.0723 0.5031
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0241 0.1195
Onchocerca volvulus 0.0008 0.0005 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0723 0.3582
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.0723 0.3738
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0032 0.0194 0.1322
Echinococcus granulosus peregrin 0.0008 0.0005 0.0002
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0078 0.0099
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0206 0.1022
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0014 0.0013
Brugia malayi Bromodomain containing protein 0.0008 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0102 0.013
Echinococcus multilocularis expressed protein 0.0413 0.3205 0.4246
Echinococcus multilocularis lamin 0.0058 0.0401 0.0527
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Brugia malayi hypothetical protein 0.0027 0.0157 0.0326
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0073 0.0519 0.092
Leishmania major hypothetical protein, conserved 0.0094 0.0685 0.3539
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0188 0.0392
Echinococcus multilocularis DNA directed RNA polymerase II subunit RPB2 0.0014 0.0052 0.0064
Loa Loa (eye worm) hypothetical protein 0.0028 0.0164 0.0212
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0251 0.1926 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0919 0.1214
Trichomonas vaginalis dihydroflavonal-4-reductase, putative 0.0027 0.0157 0.0778
Plasmodium vivax SET domain protein, putative 0.0034 0.0209 0.0365
Brugia malayi Bromodomain containing protein 0.0008 0.0005 0.0004
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0054 0.0249
Echinococcus granulosus histone acetyltransferase KAT2B 0.0096 0.0698 0.0921
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0022
Echinococcus multilocularis polybromo 1 0.0008 0.0005 0.0002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0054 0.0266
Loa Loa (eye worm) hypothetical protein 0.0045 0.0299 0.0392
Echinococcus granulosus DNA directed RNA polymerase II subunit RPB2 0.0014 0.0052 0.0064
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0015 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0209 0.0272
Schistosoma mansoni helicase 0.0008 0.0005 0.0002
Echinococcus granulosus histone acetyltransferase KAT2B 0.0316 0.2439 0.3231
Schistosoma mansoni hypothetical protein 0.007 0.0498 0.0655
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0005 0.0002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0241 0.1195
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Onchocerca volvulus 0.0008 0.0005 0.0009
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0716 0.5597 0.5595
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0251 0.1926 1
Echinococcus multilocularis geminin 0.0177 0.1343 0.1776
Leishmania major NAD synthase, putative 0.008 0.0571 0.2946
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0251 0.1926 1
Brugia malayi oxidoreductase 0.0027 0.0157 0.0326
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0251 0.1926 1
Trypanosoma brucei glucosidase, putative 0.0038 0.0241 0.123
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0206 0.1022
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0014 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Schistosoma mansoni regulator of G protein signaling 0.0021 0.011 0.0141
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0444 0.0584
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0109 0.0172
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0014 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0723 0.3582
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0251 0.1926 1
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.008 0.0571 0.1012
Trypanosoma cruzi GUP1, putative 0.0094 0.0685 0.3539
Brugia malayi dihydrofolate reductase family protein 0.0167 0.1258 0.2661
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.011 0.0226
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0325 0.2511 0.3326
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0251 0.1926 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.011 0.0545
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0014 0.0021
Brugia malayi phosphofructokinase 0.0124 0.0919 0.1942
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0094 0.0685 0.4763
Schistosoma mansoni ferritin 0.0009 0.0013 0.0012
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0155 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0685 0.3393
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0027 0.0152 0.0753
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0496 0.3441
Onchocerca volvulus 0.0008 0.0005 0.0009
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) hypothetical protein 0.0027 0.0152 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.011 0.0545
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0014 0.0052 0.0064
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0032 0.0194 0.0983
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0014 0.006
Plasmodium vivax bromodomain protein, putative 0.0008 0.0005 0.0001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0155 0.015
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0094 0.0685 0.0904
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0094 0.0685 0.0904
Schistosoma mansoni hypothetical protein 0.0022 0.012 0.0154
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0008 0.0005 0.0002
Brugia malayi hypothetical protein 0.001 0.0017 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Echinococcus granulosus Bromodomain containing protein 0.0008 0.0005 0.0002
Brugia malayi Bromodomain containing protein 0.0008 0.0005 0.0004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.011 0.0545
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Onchocerca volvulus 0.0027 0.0155 0.0753
Giardia lamblia Transcription regulatory protein SNF2 0.0008 0.0005 0.00000000040833
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus multilocularis musashi 0.0058 0.0401 0.0527
Schistosoma mansoni DNA helicase recq5 0.0009 0.0014 0.0013
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0269 0.2066 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0109 0.054
Brugia malayi Bromodomain containing protein 0.0008 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Echinococcus multilocularis zinc finger protein 0.001 0.002 0.0022
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0109 0.0186
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0206 0.141
Brugia malayi PHD-finger family protein 0.001 0.002 0.0035
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0008 0.0005 0.0002
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0008 0.0005 0.0003
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.011 0.0141
Echinococcus granulosus DNA directed RNA polymerase III subunit RPC2 0.0014 0.0052 0.0064
Onchocerca volvulus 0.0032 0.0196 0.0957
Onchocerca volvulus Brd8 homolog 0.0008 0.0005 0.0009
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Brugia malayi CXXC zinc finger family protein 0.0032 0.0196 0.0409
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0444 0.2285
Brugia malayi Doublecortin family protein 0.0022 0.012 0.0246
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0206 0.141
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0102 0.0173
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.000000000029303 0.00000000014518
Schistosoma mansoni DNA-directed rna polymerase II subunit 0.0014 0.0052 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.011 0.0545
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0142 0.0184
Giardia lamblia Synaptic glycoprotein SC2 0.0027 0.0152 0.2043
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0189 0.1432 1
Brugia malayi Bromodomain containing protein 0.0008 0.0005 0.0004
Brugia malayi 6-phosphofructokinase 0.0124 0.0919 0.1942
Onchocerca volvulus 0.0012 0.0039 0.0174
Echinococcus multilocularis DNA directed RNA polymerase III subunit RPC2 0.0014 0.0052 0.0064
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0094 0.0685 0.0904
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0113 0.0144
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0005 0.0003
Entamoeba histolytica hypothetical protein, conserved 0.0094 0.0685 0.4763
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0094 0.0685 0.4763
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0241 0.123
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0269 0.2066 0.3574
Trichomonas vaginalis hydroxysteroid dehydrogenase, putative 0.0027 0.0157 0.0778
Plasmodium falciparum bromodomain protein 2, putative 0.0008 0.0005 0.0001
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0094 0.0685 0.0904
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0015 0.0015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0677 0.4707
Brugia malayi polybromodomain protein 0.0008 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.011 0.0545
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0013 0.0008
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0008 0.0005 0.0003
Schistosoma mansoni polybromo-1 0.0008 0.0005 0.0002
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0064 0.0445 0.0787
Onchocerca volvulus 0.0027 0.0157 0.0761
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0027 0.0152 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0109 0.014
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0209 0.0272
Trypanosoma cruzi GUP1, putative 0.0094 0.0685 0.3539
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0054 0.0254
Entamoeba histolytica NAD synthetase, putative 0.008 0.0571 0.3965
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0109 0.0539
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0094 0.0685 0.0904
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0251 0.1926 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0401 0.0527
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0027 0.0152 0.103
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0155 0.015
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0094 0.0685 0.0904
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0027 0.0152 0.0753
Trypanosoma cruzi bromodomain factor 2 protein 0.0008 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0102 0.013
Mycobacterium ulcerans arylamine N-acetyltransferase Nat 0.1274 1 1
Brugia malayi hypothetical protein 0.0022 0.012 0.0246
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0155 0.1054
Schistosoma mansoni lipoxygenase 0.0063 0.0438 0.0577
Giardia lamblia DNA-directed RNA polymerase RPB2 0.0014 0.0052 0.0649
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus multilocularis protein kinase C binding protein 1 0.0008 0.0005 0.0002
Brugia malayi DNA-directed RNA polymerase II second largest subunit, putative 0.0014 0.0052 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Mycobacterium ulcerans hydrolase 0.001 0.0017 0.0013
Echinococcus granulosus Bromodomain containing protein 0.0008 0.0005 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0093 0.0088
Brugia malayi PXA domain containing protein 0.0021 0.011 0.0226
Onchocerca volvulus 0.0008 0.0005 0.0009
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0113 0.0144
Schistosoma mansoni hypothetical protein 0.0008 0.0005 0.0002
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.008 0.0571 0.2828
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0329 0.1629
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0005 0.0003
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0677 0.4707
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0723 0.3582
Loa Loa (eye worm) DNA-directed RNA polymerase 0.0011 0.0032 0.0038
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.011 0.0226
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0014 0.0052 0.0257
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0206 0.2799
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0241 0.1655
Loa Loa (eye worm) bromodomain containing protein 0.0008 0.0005 0.0002
Onchocerca volvulus 0.0008 0.0005 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0919 0.4552
Loa Loa (eye worm) hypothetical protein 0.002 0.0102 0.013
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Schistosoma mansoni lamin 0.0058 0.0401 0.0527
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0109 0.0539
Brugia malayi Bromodomain containing protein 0.0008 0.0005 0.0004
Schistosoma mansoni bromodomain containing protein 0.001 0.002 0.0022
Schistosoma mansoni hypothetical protein 0.0177 0.1343 0.1776
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0716 0.5597 1
Schistosoma mansoni ferritin light chain 0.0009 0.0013 0.0012
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0251 0.1926 1
Plasmodium falciparum DNA-directed RNA polymerase II subunit RPB2, putative 0.0014 0.0052 0.0084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.000000000029303 0.00000000014518
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0141
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0014 0.0052 0.0329
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0018
Mycobacterium ulcerans 6-phosphofructokinase 0.0124 0.0919 0.0914
Trypanosoma brucei Bromodomain, putative 0.0008 0.0005 0.0002
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.011 0.0141
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0102 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus granulosus DNA directed RNA polymerase I subunit RPA2 0.0014 0.0052 0.0064
Leishmania major hypothetical protein, conserved 0.0027 0.0157 0.0792
Trichomonas vaginalis set domain proteins, putative 0.0263 0.2018 1
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0189 0.1432 0.3032
Trypanosoma brucei DNA-directed RNA polymerase III, putative 0.0014 0.0052 0.0244
Brugia malayi small heat shock protein 0.0605 0.4715 1
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0401 0.0843
Echinococcus multilocularis DNA directed RNA polymerase I subunit RPA2 0.0014 0.0052 0.0064
Giardia lamblia DNA-directed RNA polymerase subunit B 0.0014 0.0052 0.0649
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0094 0.0685 0.0904
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0401 0.0527
Trypanosoma cruzi RNA polymerase I second largest subunit, putative 0.001 0.0021 0.0084
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.001 0.0017 0.0069
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.1289 0.1705
Brugia malayi Sulfatase family protein 0.001 0.0017 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Loa Loa (eye worm) hypothetical protein 0.0094 0.0685 0.0904
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0113 0.0144
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0008 0.0005 0.0002
Trypanosoma cruzi NAD+ synthase, putative 0.008 0.0571 0.2946
Plasmodium falciparum polyprenol reductase, putative 0.0027 0.0152 0.0263
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0113 0.0144
Brugia malayi Pre-SET motif family protein 0.0034 0.0209 0.0436
Entamoeba histolytica acetyltransferase, GNAT family 0.0088 0.0635 0.4413
Echinococcus granulosus PH interacting protein 0.0008 0.0005 0.0002
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.001 0.0017 0.0013
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.012 0.0205
Echinococcus multilocularis jun protein 0.0087 0.0626 0.0825
Loa Loa (eye worm) hypothetical protein 0.0034 0.0209 0.0272
Echinococcus granulosus o acyltransferase membrane bound domain 0.0094 0.0685 0.0904
Trypanosoma brucei calpain, putative 0.0251 0.1926 1
Toxoplasma gondii DNA-directed RNA polymerase II RPB2 0.0014 0.0052 0.0329
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.012 0.0154
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0241 0.1195
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0008 0.0005 0.0002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0189 0.1432 0.7096
Mycobacterium tuberculosis Possible hydrolase 0.001 0.0017 0.0013
Plasmodium falciparum bromodomain protein, putative 0.0008 0.0005 0.0001
Brugia malayi follicle stimulating hormone receptor 0.0519 0.4036 0.8559
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0444 0.0584
Mycobacterium ulcerans cholesterol dehydrogenase 0.0328 0.2529 0.2525
Schistosoma mansoni cpg binding protein 0.0034 0.0211 0.0275
Brugia malayi Bromodomain containing protein 0.0008 0.0005 0.0004
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0013 0.0008
Schistosoma mansoni DNA-directed RNA polymerase I subunit 0.001 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.0094 0.0685 0.0904
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0716 0.5597 0.5595
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0005 0.0003
Echinococcus granulosus bromodomain containing protein 8 0.0008 0.0005 0.0002
Loa Loa (eye worm) MBOAT family protein 0.0094 0.0685 0.0904
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0152 0.0753
Echinococcus granulosus RUN 0.0022 0.012 0.0154
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0113 0.0231
Trypanosoma cruzi DNA-directed RNA polymerase II subunit 2, putative 0.0009 0.0015 0.0051
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.012 0.0154
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0189 0.1432 0.7431
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0031 0.0036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.000000000029303 0.00000000014518
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0094 0.0685 0.0904
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.012 0.0154
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.000000000029303 0.00000000014518
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0444 0.0439
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0034 0.0206
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0209 0.0272
Trypanosoma brucei Bromodomain, putative 0.0008 0.0005 0.0002
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.008 0.0571 0.3965
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0096 0.0698 0.4854
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0241 0.1195
Schistosoma mansoni alpha-glucosidase 0.0147 0.1101 0.1456
Onchocerca volvulus 0.0022 0.012 0.0575
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.011 0.0141
Trypanosoma brucei DNA-directed RNA polymerase II subunit 2, putative 0.0014 0.0052 0.0244
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0005 0.0003
Trichomonas vaginalis dihydroflavonal-4-reductase, putative 0.0027 0.0157 0.0778
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0032 0.0194 0.0337
Brugia malayi bromodomain containing protein 0.0008 0.0005 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0209 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0919 0.4552
Schistosoma mansoni polycystin 1-related 0.0022 0.012 0.0154
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.011 0.0141
Echinococcus multilocularis bromodomain containing protein 8 0.0008 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Plasmodium falciparum DNA-directed RNA polymerase III subunit RPC2, putative 0.0014 0.0052 0.0084
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0015 0.0015
Schistosoma mansoni alpha-glucosidase 0.0147 0.1101 0.1456
Onchocerca volvulus 0.0058 0.0401 0.1972
Onchocerca volvulus 0.0027 0.0152 0.0737
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0014 0.0021
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0005 0.0002
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0014 0.0052 0.0329
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0094 0.0685 0.0904
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Brugia malayi GMP synthase 0.0032 0.0194 0.0403
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0027 0.0152 0.0765
Echinococcus multilocularis Bromodomain containing protein 0.0008 0.0005 0.0002
Echinococcus granulosus global transcription activator snf2l2 0.0008 0.0005 0.0002
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0716 0.5597 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0109 0.0727
Loa Loa (eye worm) hhat protein 0.0094 0.0685 0.0904
Loa Loa (eye worm) hypothetical protein 0.0605 0.4715 0.625
Loa Loa (eye worm) RGS-3 protein 0.0021 0.011 0.0141
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0716 0.5597 1
Brugia malayi Dihydrofolate reductase 0.0167 0.1258 0.2661
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0008 0.0005 0.0027
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0005 0.0003
Leishmania major glycerol uptake protein, putative 0.0094 0.0685 0.3539
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0206 0.141
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Loa Loa (eye worm) acetyltransferase 0.0325 0.2511 0.3326
Schistosoma mansoni rab6-interacting 0.0022 0.012 0.0154
Echinococcus multilocularis sterol O acyltransferase 1 0.0963 0.7542 1
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0005 0.0027
Plasmodium vivax bromodomain protein, putative 0.0008 0.0005 0.0001
Echinococcus granulosus lamin dm0 0.0058 0.0401 0.0527
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0014 0.0052 0.0064
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.011 0.0545
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0115 0.0236
Trichomonas vaginalis ferritin, putative 0.0009 0.0013 0.0062
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.012 0.0205
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0269 0.2066 0.2062
Echinococcus granulosus cpg binding protein 0.0034 0.0211 0.0275
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Brugia malayi PXA domain containing protein 0.0021 0.011 0.0226
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.011 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0005 0.0027
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0115 0.0147
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0209 0.0272
Giardia lamblia Hypothetical protein 0.001 0.0017 0.0168
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0206 0.1022
Brugia malayi hypothetical protein 0.0022 0.012 0.0246
Entamoeba histolytica ankyrin repeat protein, putative 0.0008 0.0005 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0241 0.1195
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0096 0.0698 0.1239
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0027 0.0152 0.0753
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0194 0.0252
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0109 0.0469
Mycobacterium ulcerans arylsulfatase AtsD 0.001 0.0017 0.0013
Schistosoma mansoni regulator of G protein signaling 0.0021 0.011 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0113 0.0144
Echinococcus multilocularis dnaJ subfamily B 0.0911 0.7135 0.946
Onchocerca volvulus 0.0068 0.0479 0.2359
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0054 0.0266
Schistosoma mansoni hypothetical protein 0.0008 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0155 0.0201
Loa Loa (eye worm) oxidoreductase 0.0008 0.0005 0.0002
Brugia malayi Hhat protein 0.0094 0.0685 0.1446
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0919 0.1214
Giardia lamblia Kinase, PLK 0.0099 0.0723 1
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0716 0.5597 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0094 0.0685 0.4763
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0093 0.0088
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0027 0.0152 0.103
Echinococcus multilocularis PH interacting protein 0.0008 0.0005 0.0002
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0014 0.0072
Schistosoma mansoni rab6-interacting 0.0022 0.012 0.0154
Toxoplasma gondii hypothetical protein 0.0094 0.0685 0.4763
Toxoplasma gondii DNA-directed RNA polymerase III RPC2 0.0014 0.0052 0.0329
Loa Loa (eye worm) hypothetical protein 0.0058 0.0401 0.0527
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0109 0.1441
Loa Loa (eye worm) hypothetical protein 0.002 0.0102 0.013
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.011 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0241 0.1195
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.011 0.0141
Schistosoma mansoni ap endonuclease 0.0021 0.0109 0.014
Mycobacterium ulcerans hypothetical protein 0.0189 0.1432 0.1428
Loa Loa (eye worm) hypothetical protein 0.002 0.0102 0.013
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0027 0.0152 0.0765
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0206 0.036
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0206 0.1022
Giardia lamblia Hypothetical protein 0.001 0.0017 0.0168
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0206 0.141
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0005 0.0002
Mycobacterium ulcerans arylsulfatase AtsB 0.001 0.0017 0.0013
Schistosoma mansoni lipoxygenase 0.0022 0.012 0.0154
Schistosoma mansoni regulator of G protein signaling 0.0021 0.011 0.0141
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0014 0.0052 0.0257
Mycobacterium ulcerans NAD synthetase 0.008 0.0571 0.0566
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0155 0.015
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0167 0.1258 0.6079
Echinococcus multilocularis RUN 0.0022 0.012 0.0154
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0164 0.0212
Loa Loa (eye worm) CBP-B 0.0008 0.0005 0.0002
Brugia malayi acetyltransferase, GNAT family protein 0.0325 0.2511 0.5322
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0251 0.1926 1
Leishmania major DNA-directed RNA polymerase polypeptide, putative 0.0014 0.0052 0.0244
Trichomonas vaginalis transmembrane protein nessy, putative 0.0094 0.0685 0.3393
Loa Loa (eye worm) hhat protein 0.0094 0.0685 0.0904
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0444 0.0934
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0005 0.0027
Schistosoma mansoni DNA helicase recq1 0.0009 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0157 0.0204
Echinococcus granulosus dnaJ subfamily B 0.0911 0.7135 0.946
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0102 0.0097
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0054 0.0266
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0054 0.0254
Loa Loa (eye worm) MBOAT family protein 0.0094 0.0685 0.0904
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trypanosoma cruzi glycerol uptake protein, putative 0.0094 0.0685 0.3539
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis porcupine, putative 0.0094 0.0685 0.3393
Schistosoma mansoni ferritin 0.0009 0.0013 0.0012
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0919 0.1214
Entamoeba histolytica hypothetical protein 0.0021 0.011 0.0736
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0094 0.0685 0.0904
Brugia malayi ATPase, AAA family protein 0.0008 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0919 0.1214
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.012 0.0154
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.000000000029303 0.00000000014518
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Echinococcus granulosus zinc finger protein 0.001 0.002 0.0022
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0057 0.0368
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0155 0.0783
Echinococcus multilocularis microtubule associated protein 2 0.0711 0.5557 0.7367
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0093 0.0088
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.011 0.0141
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0015 0.0015
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0109 0.014
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0005 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0005 0.0003
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0005 0.0027
Echinococcus granulosus bloom syndrome protein 0.0022 0.0115 0.0147
Schistosoma mansoni apoferritin-2 0.0009 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0869 0.68 0.9015
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0054 0.0266
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0109 0.054
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0063 0.0438 0.0577
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.001 0.002 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Echinococcus granulosus expressed protein 0.0413 0.3205 0.4246
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0171 0.1289 0.1705
Trypanosoma cruzi glycerol uptake protein, putative 0.0094 0.0685 0.3539
Plasmodium vivax GMP synthetase, putative 0.0032 0.0194 0.0337
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis lymphoid specific helicase, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.000000000029303 0.00000000014518
Trypanosoma cruzi Bromodomain factor 1 0.0008 0.0005 0.0002
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0206 0.0943
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Loa Loa (eye worm) RNA polymerase III 128kD subunit-PA 0.0014 0.0052 0.0064
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0251 0.1926 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.012 0.0154
Onchocerca volvulus 0.0034 0.0209 0.1019
Brugia malayi Pre-SET motif family protein 0.0231 0.1767 0.3743
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trypanosoma brucei Bromodomain, putative 0.0008 0.0005 0.0002
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0124 0.0919 0.4434
Brugia malayi Bromodomain containing protein 0.001 0.002 0.0035
Plasmodium vivax DNA-directed RNA polymerase I subunit RPA2, putative 0.001 0.0021 0.0029
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0155 0.015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0005 0.0001
Trypanosoma brucei AAA ATPase, putative 0.0008 0.0005 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0723 0.3582
Trichomonas vaginalis DNA-directed RNA polymerase III subunit, putative 0.0014 0.0052 0.0257
Plasmodium falciparum DNA-directed RNA polymerase I subunit RPA2, putative 0.001 0.0021 0.0029
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0066 0.0462 0.0457
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.041 0.0539
Brugia malayi intermediate filament protein 0.0058 0.0401 0.0843
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0115 0.0568
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.011 0.0141
Schistosoma mansoni bromodomain containing protein 0.0008 0.0005 0.0002
Leishmania major glycerol uptake protein, putative 0.0094 0.0685 0.3539
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0008 0.0005 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0155 0.015
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0008 0.0005 0.0002
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0444 0.0584
Onchocerca volvulus 0.0263 0.2018 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0008 0.0005 0.0027
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.011 0.0226
Echinococcus granulosus axis inhibition protein axin 0.0021 0.011 0.0141
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.011 0.0141
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0109 0.014
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0109 0.0223
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0155 0.1054
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0032 0.0194 0.0252
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0723 0.3582
Loa Loa (eye worm) hypothetical protein 0.0057 0.0393 0.0516
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus granulosus synaptic glycoprotein sc2 0.0027 0.0152 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trypanosoma brucei calpain-like protein, putative 0.0251 0.1926 1
Mycobacterium ulcerans sulfatase 0.001 0.0017 0.0013
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0189 0.1432 0.7431
Schistosoma mansoni microtubule-associated protein tau 0.0711 0.5557 0.7367
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0027 0.0152 0.103
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0008 0.0005 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0685 0.3393
Schistosoma mansoni ferritin light chain 0.0009 0.0013 0.0012
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.001 0.0017 0.0013
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.1767 0.2339
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0677 0.4707
Entamoeba histolytica hypothetical protein 0.0027 0.0152 0.103
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0034 0.0153
Brugia malayi hypothetical protein 0.0021 0.011 0.0226
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0005 0.0027
Echinococcus multilocularis dihydrofolate reductase 0.0167 0.1258 0.1663
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.0723 0.0954
Echinococcus granulosus ferritin 0.0009 0.0013 0.0012
Entamoeba histolytica hypothetical protein 0.0008 0.0005 0.0003
Loa Loa (eye worm) dihydrofolate reductase 0.0167 0.1258 0.1663
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0155 0.0322
Leishmania major ATP-dependent phosphofructokinase 0.0124 0.0919 0.4758
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0094 0.0685 0.0904
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Schistosoma mansoni zinc finger protein 0.0094 0.0685 0.0904
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0167 0.1258 0.1253
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.011 0.0141
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0064 0.0445 0.3085
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.001 0.0017 0.0087
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0155 0.1054
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0677 0.4707
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.011 0.0141
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0209 0.1429
Schistosoma mansoni ferritin 0.0009 0.0013 0.0012
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0008 0.0005 0.0003
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0094 0.0159
Loa Loa (eye worm) RecQ helicase 0.0022 0.0115 0.0147
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0109 0.054
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus granulosus lamin 0.0058 0.0401 0.0527
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0048 0.032 0.0419
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Brugia malayi DNA-directed RNA polymerase, beta subunit family protein 0.0014 0.0052 0.0103
Schistosoma mansoni cpg binding protein 0.0034 0.0211 0.0275
Echinococcus multilocularis bromodomain containing 2 0.0008 0.0005 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0027 0.0152 0.0197
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0723 0.3738
Onchocerca volvulus 0.0099 0.0721 0.3561
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0013
Plasmodium vivax DNA-directed RNA polymerase II subunit RPB2, putative 0.0014 0.0052 0.0084
Toxoplasma gondii hypothetical protein 0.0045 0.0299 0.2061
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0063 0.0438 0.0577
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0031 0.0036
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0014 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Toxoplasma gondii exonuclease III APE 0.0021 0.0109 0.0727
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) hypothetical protein 0.0027 0.0157 0.0204
Trichomonas vaginalis bromodomain-containing protein, putative 0.0096 0.0698 0.3457
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0113 0.0144
Plasmodium falciparum bromodomain protein 1 0.0008 0.0005 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0157 0.0792
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.0723 0.0954
Loa Loa (eye worm) hypothetical protein 0.0014 0.0054 0.0066
Echinococcus granulosus polybromo 1 0.0008 0.0005 0.0002
Echinococcus granulosus CREB binding protein 0.0008 0.0005 0.0002
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0124 0.0919 0.0914
Treponema pallidum NAD synthetase 0.008 0.0571 0.272
Giardia lamblia NH3-dependent NAD+ synthetase 0.008 0.0571 0.788
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0241 0.123
Trypanosoma brucei glycerol uptake protein, putative 0.0094 0.0685 0.3539
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0054 0.0266
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0005 0.0003
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0014 0.0113
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0008 0.0005 0.0002
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0094 0.0685 0.1216
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0096 0.0698 0.4854
Schistosoma mansoni alpha glucosidase 0.0038 0.0241 0.0315
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0014 0.0072
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.011 0.0141
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0005 0.0025
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0064 0.0445 0.2293
Schistosoma mansoni loxhd1 0.0022 0.012 0.0154
Echinococcus multilocularis global transcription activator snf2l2 0.0008 0.0005 0.0002
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0064 0.0445 0.2293
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.000000000029303 0.00000000014518
Brugia malayi 6-phosphofructokinase 0.0124 0.0919 0.1942
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0251 0.1926 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0064 0.0445 0.2293
Schistosoma mansoni ferritin 0.0009 0.0013 0.0012
Echinococcus granulosus expressed protein 0.0009 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0141
Loa Loa (eye worm) hypothetical protein 0.0027 0.0155 0.0201
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Onchocerca volvulus 0.0008 0.0005 0.0007
Brugia malayi MBOAT family protein 0.0094 0.0685 0.1446
Schistosoma mansoni CREB-binding protein 2 0.0008 0.0005 0.0002
Giardia lamblia DNA-directed RNA polymerase subunit B 0.001 0.0021 0.0218
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.012 0.0154
Echinococcus granulosus 6 phosphofructokinase 0.0124 0.0919 0.1214
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0251 0.1926 1
Echinococcus granulosus jun protein 0.0087 0.0626 0.0825
Plasmodium vivax bromodomain protein, putative 0.0008 0.0005 0.0001
Brugia malayi MBOAT family protein 0.0094 0.0685 0.1446
Echinococcus granulosus sterol O acyltransferase 1 0.0963 0.7542 1
Loa Loa (eye worm) hypothetical protein 0.0963 0.7542 1
Echinococcus granulosus bromodomain containing 2 0.0008 0.0005 0.0002
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0032 0.0194 0.0252
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0022
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.001 0.0017 0.0087
Plasmodium falciparum histone acetyltransferase GCN5 0.0088 0.0635 0.1126
Brugia malayi Cytochrome P450 family protein 0.0025 0.0142 0.0295
Echinococcus multilocularis 0.0008 0.0005 0.0002
Schistosoma mansoni transcription initiation factor tfiid 0.0008 0.0005 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trypanosoma brucei glycerol uptake protein, putative 0.0094 0.0685 0.3539
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0141
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0032 0.0194 0.0983
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0188 0.0245
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0155 0.073
Leishmania major glycerol uptake protein, putative 0.0094 0.0685 0.3539
Trypanosoma brucei hypothetical protein 0.0251 0.1926 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.011 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0723 0.3582
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0109 0.054
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0005 0.0025
Leishmania major hypothetical protein, conserved 0.0008 0.0005 0.0002
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0054 0.0254
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0034 0.0171
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0054 0.0342
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0189 0.1432 0.7096
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0157 0.0792
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.011 0.0141
Schistosoma mansoni hypothetical protein 0.0008 0.0005 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trypanosoma brucei NAD(P)-dependent steroid dehydrogenase protein, putative 0.0027 0.0157 0.0792
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.011 0.0141
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0241 0.0504
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Mycobacterium ulcerans hypothetical protein 0.0027 0.0155 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trypanosoma brucei nadh-ubiquinone oxidoreductase 39 kda subunit 0.0027 0.0157 0.0792
Echinococcus granulosus lysosomal alpha glucosidase 0.0171 0.1289 0.1705
Loa Loa (eye worm) hypothetical protein 0.0027 0.0155 0.0201
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.011 0.0141
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0919 0.4758
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Echinococcus multilocularis synaptic glycoprotein sc2 0.0027 0.0152 0.0197
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0329 0.1629
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0269 0.2066 0.3676
Loa Loa (eye worm) DNA-directed RNA polymerase II second largest subunit 0.0014 0.0052 0.0064
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0491 0.0646
Toxoplasma gondii DNA-directed RNA polymerase I RPA2 0.001 0.0021 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0189 0.1432 0.7096
Echinococcus multilocularis expressed protein 0.0009 0.0013 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0241 0.1195
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.1289 0.1705
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0157 0.0792
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0027 0.0152 0.0753
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.008 0.0571 0.1012
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0241 0.0315
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0005 0.0003
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0005 0.0003
Brugia malayi diacylglycerol acyltransferase 0.0094 0.0685 0.1446
Trypanosoma cruzi bromodomain-containing protein 3 0.0008 0.0005 0.0002
Leishmania major glycerol uptake protein, putative 0.0094 0.0685 0.3539
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.0723 0.1527
Trypanosoma brucei polo-like protein kinase 0.0099 0.0723 0.3738
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trypanosoma cruzi glycerol uptake protein, putative 0.0094 0.0685 0.3539
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trypanosoma brucei Bromodomain factor 1 0.0008 0.0005 0.0002
Schistosoma mansoni intermediate filament proteins 0.0058 0.0401 0.0527
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0716 0.5597 0.5595
Treponema pallidum alginate O-acetylation protein (algI) 0.0094 0.0685 0.3274
Schistosoma mansoni axis inhibition protein axin 0.0021 0.011 0.0141
Mycobacterium ulcerans bacterioferritin BfrB 0.0009 0.0013 0.0008
Trypanosoma cruzi NAD+ synthase, putative 0.008 0.0571 0.2946
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.011 0.0141
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.0723 0.3571
Echinococcus granulosus dihydrofolate reductase 0.0167 0.1258 0.1663
Echinococcus granulosus intermediate filament protein 0.0058 0.0401 0.0527
Entamoeba histolytica hypothetical protein 0.0021 0.011 0.0736
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0034 0.0153
Schistosoma mansoni phd finger protein 0.0008 0.0005 0.0002
Onchocerca volvulus 0.0022 0.012 0.0575
Loa Loa (eye worm) hypothetical protein 0.0022 0.012 0.0154
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0716 0.5597 0.5595
Schistosoma mansoni lamin 0.0058 0.0401 0.0527
Echinococcus multilocularis Bromodomain containing protein 0.0008 0.0005 0.0002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0164 0.0212
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0005 0.0003
Onchocerca volvulus 0.0094 0.0685 0.3381
Schistosoma mansoni hypothetical protein 0.0911 0.7135 0.946
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0206 0.036
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0014 0.0013
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0723 0.3738
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0155 0.0322
Toxoplasma gondii hypothetical protein 0.0008 0.0005 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0723 0.0954
Mycobacterium ulcerans arylsulfatase AtsD 0.001 0.0017 0.0013
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0519 0.4036 0.535
Echinococcus granulosus axis inhibition protein axin 0.0021 0.011 0.0141
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0009 0.0013 0.0037
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0206 0.019
Leishmania major RNA polymerase I second largest subunit, putative 0.001 0.0021 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0027 0.0152 0.0197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.000000000029303 0.00000000014518
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0087 0.0626 0.0825
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0206 0.1022
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0054 0.0106
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0269 0.2066 1
Entamoeba histolytica hypothetical protein 0.0094 0.0685 0.4763
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0059 0.0096
Brugia malayi MBOAT family protein 0.0094 0.0685 0.1446
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0094 0.0685 0.4763
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Schistosoma mansoni hypothetical protein 0.0094 0.0685 0.0904
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0206 0.1022
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0005 0.0002
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0005 0.0002
Giardia lamblia Histone acetyltransferase GCN5 0.0088 0.0635 0.8772
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0189 0.1432 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0206 0.019
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0087 0.0626 0.0825
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0155 0.073
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0155 0.0322
Brugia malayi hypothetical protein 0.0135 0.1006 0.2128
Brugia malayi BRM protein 0.0008 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Onchocerca volvulus UPF0528 protein homolog 0.0045 0.0299 0.1467
Schistosoma mansoni bromodomain containing protein 0.001 0.002 0.0022
Leishmania major hypothetical protein, conserved 0.0008 0.0005 0.0002
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0241 0.123
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0919 0.6402
Loa Loa (eye worm) hypothetical protein 0.0027 0.0157 0.0204
Trypanosoma brucei NAD(p)-dependent steroid dehydrogenase-like protein 0.0027 0.0157 0.0792
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0196 0.0256
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0206 0.036
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0054 0.0266
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0005 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0155 0.0783
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.011 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0723 0.3582
Echinococcus granulosus microtubule associated protein 2 0.0711 0.5557 0.7367
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0241 0.1195
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0094 0.0685 0.0904
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0054 0.0266
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Schistosoma mansoni regulator of G protein signaling 0.0021 0.011 0.0141
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus multilocularis ferritin 0.0009 0.0013 0.0012
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0094 0.0685 0.0904
Schistosoma mansoni hypothetical protein 0.0008 0.0005 0.0002
Schistosoma mansoni kinase 0.005 0.0339 0.0445
Trichomonas vaginalis hypothetical protein 0.0008 0.0005 0.0027
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0005 0.0027
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0094 0.0685 0.0904
Leishmania major NAD(p)-dependent steroid dehydrogenase-like protein 0.0027 0.0157 0.0792
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0008 0.0005 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Schistosoma mansoni apoferritin-2 0.0009 0.0013 0.0012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0093 0.0088
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0677 0.4707
Trypanosoma brucei RNA polymerase I second largest subunit 0.001 0.0021 0.0084
Echinococcus granulosus CREB binding protein 0.0008 0.0005 0.0002
Echinococcus multilocularis 6 phosphofructokinase 0.0124 0.0919 0.1214
Brugia malayi Bromodomain containing protein 0.0008 0.0005 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0155 0.015
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0124 0.0919 0.4414
Plasmodium vivax polyprenol reductase, putative 0.0027 0.0152 0.0263
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0096 0.0698 0.3457
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0919 0.6402
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0008 0.0005 0.0002
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0094 0.0685 0.0904
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0094 0.0685 0.4763
Entamoeba histolytica DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide, putative 0.0014 0.0052 0.0329
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Plasmodium vivax DNA-directed RNA polymerase III subunit, putative 0.0014 0.0052 0.0084
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0157 0.0792
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0919 0.4552
Schistosoma mansoni bromodomain containing 0.0008 0.0005 0.0002
Brugia malayi hypothetical protein 0.0021 0.011 0.0226
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.012 0.0154
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trypanosoma brucei NAD+ synthase, putative 0.008 0.0571 0.2946
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0251 0.1926 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Brugia malayi Glycosyl hydrolases family 31 protein 0.0171 0.1289 0.2728
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0241 0.1195
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0325 0.2511 0.3326
Loa Loa (eye worm) hypothetical protein 0.0027 0.0152 0.0197
Brugia malayi MBOAT family protein 0.0094 0.0685 0.1446
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0094 0.0685 0.0904
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.011 0.0141
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) hypothetical protein 0.0032 0.0194 0.0252
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0094 0.0685 0.0904
Schistosoma mansoni jun-related protein 0.007 0.0498 0.0655
Brugia malayi NC domain containing protein 0.0045 0.0299 0.0627
Loa Loa (eye worm) hypothetical protein 0.0027 0.0155 0.0201
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0209 0.0272
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0102 0.0173
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0054 0.0266
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.008 0.0571 0.0752
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Loa Loa (eye worm) doublecortin family protein 0.0022 0.012 0.0154
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0206 0.1022
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0027 0.0152 0.0197
Schistosoma mansoni ap endonuclease 0.0021 0.0109 0.014
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0241 0.1655
Entamoeba histolytica hypothetical protein 0.0021 0.011 0.0736
Plasmodium vivax SET domain containing protein 0.001 0.0021 0.0028
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0027 0.0152 0.103
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0189 0.1432 0.7431
Brugia malayi TAZ zinc finger family protein 0.0008 0.0005 0.0004
Brugia malayi hypothetical protein 0.0068 0.0479 0.1009
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0141
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0241 0.0315
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0919 0.4552
Chlamydia trachomatis dihydrofolate reductase 0.0167 0.1258 0.2104
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Leishmania major glycerol uptake protein, putative 0.0094 0.0685 0.3539
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0919 0.6402
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Mycobacterium ulcerans arylsulfatase, AslA 0.001 0.0017 0.0013
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0444 0.0439
Mycobacterium ulcerans GMP synthase 0.0032 0.0194 0.0189
Schistosoma mansoni hypothetical protein 0.0177 0.1343 0.1776
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0167 0.1258 0.1253
Brugia malayi Bromodomain containing protein 0.0008 0.0005 0.0004
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Schistosoma mansoni dihydrofolate reductase 0.0167 0.1258 0.1663
Loa Loa (eye worm) hypothetical protein 0.0017 0.008 0.0101
Trichomonas vaginalis hypothetical protein 0.0008 0.0005 0.0027
Loa Loa (eye worm) bromodomain containing protein 0.0008 0.0005 0.0002
Trichomonas vaginalis dihydroflavonal-4-reductase, putative 0.0027 0.0157 0.0778
Schistosoma mansoni sterol O-acyltransferase 1 0.0963 0.7542 1
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0005 0.0002
Loa Loa (eye worm) phosphofructokinase 0.0124 0.0919 0.1214
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0113 0.0144
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0152 0.0753
Loa Loa (eye worm) hypothetical protein 0.0351 0.2715 0.3597
Loa Loa (eye worm) hypothetical protein 0.0027 0.0155 0.0201
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0064 0.0445 0.0787
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.001 0.002 0.0022
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0444 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Echinococcus multilocularis cpg binding protein 0.0034 0.0211 0.0275
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0034 0.0153
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0115 0.0568
Onchocerca volvulus 0.0058 0.0401 0.1972
Schistosoma mansoni regulator of G protein signaling 0.0021 0.011 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0685 0.3393
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.0723 0.0954
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0109 0.0104
Loa Loa (eye worm) hypothetical protein 0.0084 0.0607 0.08
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0005 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0209 0.0272
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0251 0.1926 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0189 0.1432 0.7431
Echinococcus multilocularis CREB binding protein 0.0008 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0189 0.1432 0.1895
Schistosoma mansoni cpg binding protein 0.0032 0.0196 0.0256
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0251 0.1926 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0155 0.015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Loa Loa (eye worm) MBOAT family protein 0.0094 0.0685 0.0904
Mycobacterium ulcerans bacterioferritin BfrA 0.0009 0.0013 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0005 0.0002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Schistosoma mansoni acetyl-CoA synthetase 0.0008 0.0005 0.0002
Mycobacterium tuberculosis 3-beta-hydroxysteroid dehydrogenase 0.0328 0.2529 0.2525
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0027 0.0152 0.0197
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.008 0.0571 0.0566
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0241 0.1655
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0008 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0002
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.003 0.0055
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.011 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0017 0.0087
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0919 0.4758
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Echinococcus multilocularis lamin dm0 0.0058 0.0401 0.0527
Brugia malayi bZIP transcription factor family protein 0.0087 0.0626 0.132
Echinococcus granulosus o acyltransferase membrane bound domain 0.0094 0.0685 0.0904
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Brugia malayi Synaptic glycoprotein SC2 0.0027 0.0152 0.0315
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.011 0.0545
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0109 0.0186
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0109 0.0104

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.0969 Inhibition of Homo sapiens (human) Steroid 5-alpha-reductase type 2 ChEMBL. No reference
IC50 (binding) = 0.08 nM Inhibition of Homo sapiens (human) Steroid 5-alpha-reductase type 2 ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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