Detailed information for compound 1860264

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 415.931 | Formula: C23H27ClFN3O
  • H donors: 0 H acceptors: 1 LogP: 4.03 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)CN1CCCC(C1)C(=O)N1CCN(CC1)c1ccccc1Cl
  • InChi: 1S/C23H27ClFN3O/c24-21-5-1-2-6-22(21)27-12-14-28(15-13-27)23(29)19-4-3-11-26(17-19)16-18-7-9-20(25)10-8-18/h1-2,5-10,19H,3-4,11-17H2
  • InChiKey: RMKQJUGUKNSMDC-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0348 0.1026
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0012 0.014 0.0189
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Mycobacterium ulcerans DNA polymerase IV 0.0077 0.1297 0.4265
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0127 0.0408
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.014 0.0373
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0012 0.014 0.0373
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.014 0.0373
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Trypanosoma cruzi DNA polymerase eta, putative 0.01 0.1707 0.5726
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0012 0.014 0.0189
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0013 0.0157 0.0516
Onchocerca volvulus 0.0024 0.0348 0.1042
Trypanosoma brucei phosphoglycerate kinase 0.0171 0.2978 1
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0012 0.014 0.0373
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0025 0.0361 0.1203
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0047 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0349 0.1163
Onchocerca volvulus 0.0007 0.0047 0.0049
Trichomonas vaginalis rotamase, putative 0.0033 0.0508 0.0477
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0012 0.014 0.0149
Plasmodium vivax phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0157 0.0526
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0047 0.0059
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.014 0.014
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0012 0.014 0.046
Brugia malayi dehydrogenases, short chain protein 2 0.0012 0.014 0.0355
Schistosoma mansoni cpg binding protein 0.0029 0.0438 0.0599
Echinococcus granulosus dna polymerase kappa 0.0077 0.1297 0.1749
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.1297 0.4351
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0047 0.0149
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0223 0.0655
Plasmodium falciparum phosphatidylinositol-4-phosphate 5-kinase 0.0013 0.0157 0.0373
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Schistosoma mansoni rotamase 0.0034 0.0522 0.0715
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.014 0.0373
Loa Loa (eye worm) hypothetical protein 0.0175 0.3061 1
Toxoplasma gondii oxidoreductase, putative 0.0012 0.014 0.046
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0306 0.0902
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0012 0.014 0.046
Leishmania major short chain dehydrogenase/reductase, putative 0.0012 0.014 0.0452
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.014 0.046
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.1565 0.5108
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.014 0.014
Onchocerca volvulus 0.0019 0.0265 0.0768
Plasmodium vivax steroid dehydrogenase, putative 0.0012 0.014 0.047
Treponema pallidum phosphoglycerate kinase 0.0171 0.2978 1
Leishmania major DNA damage repair protein, putative 0.0024 0.0349 0.1155
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0039 0.0007
Trichomonas vaginalis dullard protein, putative 0.0025 0.0361 0.0329
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0012 0.014 0.014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Onchocerca volvulus 0.0007 0.0047 0.0049
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0012 0.014 0.0316
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0047 0.0049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.1565 0.2118
Echinococcus multilocularis Small ubiquitin modifier 2 0.003 0.0456 0.0585
Echinococcus granulosus carbonyl reductase 1 0.0012 0.014 0.0149
Onchocerca volvulus 0.0012 0.014 0.0355
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0175 0.3061 1
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0012 0.014 0.0149
Schistosoma mansoni phosphoglycerate kinase 0.0171 0.2978 0.4096
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0013 0.0157 0.0373
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0349 0.103
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.1297 0.4265
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.1297 0.4351
Leishmania major DNA polymerase eta, putative 0.0153 0.2655 0.8913
Onchocerca volvulus 0.0012 0.014 0.0355
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0025 0.0361 0.107
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.1565 0.5061
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0249 0.0744
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0012 0.014 0.046
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0047 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0456 0.0425
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0348 0.1079
Loa Loa (eye worm) hypothetical protein 0.0171 0.2978 0.973
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.014 0.0316
Loa Loa (eye worm) hypothetical protein 0.0007 0.0047 0.0145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.1565 0.215
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0568 0.0778
Loa Loa (eye worm) dehydrogenase 0.0012 0.014 0.0448
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0013 0.0157 0.0212
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0051 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0348 0.1026
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0082 0.0068
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0349 0.103
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.1297 0.4351
Toxoplasma gondii oxidoreductase, putative 0.0012 0.014 0.046
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0013 0.0157 0.0125
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0047 0.014
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0012 0.014 0.0316
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.1297 0.4351
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.014 0.0316
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0077 0.0061
Mycobacterium tuberculosis Probable dehydrogenase 0.0012 0.014 0.0373
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0081 0.0254
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0077 0.0102
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Echinococcus granulosus expressed protein 0.0034 0.0522 0.0677
Trypanosoma cruzi hypothetical protein 0.0006 0.0033 0.0099
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Echinococcus multilocularis dna polymerase eta 0.0153 0.2655 0.3625
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0047 0.0149
Loa Loa (eye worm) hypothetical protein 0.0024 0.0348 0.1129
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.1297 0.4177
Echinococcus multilocularis phosphoglycerate kinase 1 0.0171 0.2978 0.4072
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0012 0.014 0.046
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Loa Loa (eye worm) oxidoreductase 0.0012 0.014 0.0448
Entamoeba histolytica deoxycytidyl transferase, putative 0.0077 0.1297 0.1297
Echinococcus granulosus carbonyl reductase 1 0.0012 0.014 0.0149
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Leishmania major DNA polymerase eta, putative 0.01 0.1707 0.5722
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.014 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0349 0.103
Echinococcus granulosus phosphatidylinositol phosphate 5 kinase type III 0.0013 0.0157 0.0172
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0012 0.014 0.0316
Schistosoma mansoni cpg binding protein 0.003 0.0467 0.0639
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0348 0.1042
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.014 0.0373
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0005 0.0006 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Loa Loa (eye worm) hypothetical protein 0.0006 0.0033 0.0096
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0249 0.0689
Brugia malayi CXXC zinc finger family protein 0.0029 0.0438 0.1339
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Toxoplasma gondii propionate-CoA ligase 0.0007 0.0047 0.0149
Echinococcus granulosus Small ubiquitin modifier 2 0.003 0.0456 0.0585
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0047 0.0015
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0522 0.1698
Mycobacterium ulcerans dehydrogenase/reductase 0.0012 0.014 0.0316
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0223 0.0655
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.014 0.0373
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0025 0.0361 0.107
Trichomonas vaginalis ubiquitin, putative 0.001 0.0109 0.0077
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.014 0.014
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0012 0.014 0.014
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.014 0.0108
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0006 0.0033 0.0041
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.1297 0.4265
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Leishmania major DNA polymerase kappa, putative 0.0077 0.1297 0.4345
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0083 0.1405 0.1405
Mycobacterium tuberculosis Possible oxidoreductase 0.0012 0.014 0.0373
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Toxoplasma gondii ImpB/MucB/SamB family protein 0.01 0.1707 0.5726
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.008 0.0156
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0025 0.0361 0.1084
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0178 0.0589
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Leishmania major short chain dehydrogenase-like protein 0.0012 0.014 0.0452
Plasmodium vivax DNA repair protein REV1, putative 0.0024 0.0349 0.1173
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0039 0.0007
Trypanosoma brucei phosphoglycerate kinase 0.0063 0.1044 0.3401
Brugia malayi Pip kinase protein 2 0.0163 0.2841 0.9274
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.014 0.0316
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.014 0.0316
Leishmania major hypothetical protein, conserved 0.0012 0.014 0.0452
Loa Loa (eye worm) hypothetical protein 0.0009 0.0081 0.0254
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0361 0.1203
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Loa Loa (eye worm) oxidoreductase 0.0012 0.014 0.0448
Schistosoma mansoni dep domain containing protein 0.0009 0.0077 0.0102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0039 0.0007
Schistosoma mansoni ap endonuclease 0.0018 0.0249 0.0339
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0348 0.1026
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0077 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0077 0.1297 0.4233
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0047 0.0049
Leishmania major DNA polymerase kappa, putative 0.0024 0.0349 0.1155
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.014 0.046
Loa Loa (eye worm) hypothetical protein 0.0163 0.2841 0.9281
Brugia malayi ImpB/MucB/SamB family protein 0.0153 0.2655 0.866
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.014 0.014
Brugia malayi hypothetical protein 0.001 0.0109 0.0252
Trypanosoma cruzi short chain dehydrogenase, putative 0.0012 0.014 0.046
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0259 0.0722
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0013 0.0157 0.0508
Loa Loa (eye worm) hypothetical protein 0.0025 0.0361 0.117
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0171 0.2978 1
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0157 0.0373
Trypanosoma brucei unspecified product 0.0053 0.0871 0.2809
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0012 0.014 0.0316
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0349 0.1163
Trichomonas vaginalis helicase, putative 0.0007 0.0039 0.0007
Trypanosoma brucei unspecified product 0.0077 0.1297 0.4265
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0306 0.0274
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0012 0.014 0.0316
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0077 0.1297 0.1749
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0348 0.1079
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0012 0.014 0.0355
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0012 0.014 0.0149
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.0349 0.1163
Mycobacterium ulcerans oxidoreductase 0.0012 0.014 0.0316
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0013 0.0157 0.0125
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0163 0.2841 0.3907
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0508 0.1572
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0012 0.014 0.046
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0348 0.1026
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0012 0.014 0.0149
Trichomonas vaginalis DNA polymerase eta, putative 0.0077 0.1297 0.1269
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0105 0.0342
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Brugia malayi Phosphoglycerate kinase 0.0063 0.1044 0.3341
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0012 0.014 0.0108
Loa Loa (eye worm) FYVE zinc finger family protein 0.0013 0.0157 0.0502
Mycobacterium ulcerans carveol-like dehydrogenase 0.0012 0.014 0.0316
Loa Loa (eye worm) hypothetical protein 0.0018 0.0241 0.0777
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0348 0.1152
Echinococcus granulosus hypothetical protein 0.0012 0.014 0.0149
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0013 0.0157 0.0516
Brugia malayi oxidoreductase 0.0012 0.014 0.0355
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0047 0.0059
Brugia malayi hypothetical protein 0.0012 0.014 0.0355
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.014 0.0452
Echinococcus multilocularis dnaJ subfamily B 0.0411 0.7266 1
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0012 0.014 0.046
Loa Loa (eye worm) oxidoreductase 0.0012 0.014 0.0448
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0039 0.0007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0077 0.1297 0.4299
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.014 0.0149
Schistosoma mansoni ap endonuclease 0.0018 0.0249 0.0339
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0039 0.0007
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0012 0.014 0.0149
Echinococcus granulosus WW domain containing oxidoreductase 0.0012 0.014 0.0149
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0013 0.0157 0.0516
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.014 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0109 0.0077
Toxoplasma gondii hypothetical protein 0.0009 0.0077 0.0248
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.014 0.0452
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Schistosoma mansoni cpg binding protein 0.003 0.0467 0.0639
Loa Loa (eye worm) RasGEF domain-containing protein 0.0006 0.0033 0.0096
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0012 0.014 0.0149
Loa Loa (eye worm) oxidoreductase 0.0007 0.0047 0.0145
Plasmodium falciparum DNA repair protein REV1, putative 0.0024 0.0349 0.103
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.014 0.0149
Giardia lamblia DINP protein human, muc B family 0.0077 0.1297 0.4199
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Echinococcus granulosus dna polymerase eta 0.0153 0.2655 0.3625
Leishmania major short chain dehydrogenase, putative 0.0012 0.014 0.0452
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.014 0.0149
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0082 0.0068
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0171 0.2978 1
Leishmania major hypothetical protein, conserved 0.0012 0.014 0.0452
Loa Loa (eye worm) hypothetical protein 0.0018 0.0241 0.0777
Echinococcus multilocularis cpg binding protein 0.003 0.0467 0.0601
Brugia malayi DIX domain containing protein 0.0009 0.0077 0.0146
Onchocerca volvulus 0.0012 0.014 0.0355
Trypanosoma brucei oxidoreductase-like protein 0.0012 0.014 0.0316
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.014 0.0452
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0157 0.0263
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.014 0.0373
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0025 0.0361 0.0493
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0039 0.0007
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.014 0.0316
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0012 0.014 0.0373
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0012 0.014 0.0452
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0007 0.0047 0.0149
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0077 0.1297 0.1269
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0899 0.3013
Loa Loa (eye worm) RasGEF domain-containing protein 0.0006 0.0033 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0039 0.0007
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0171 0.2978 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.014 0.0373
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Trypanosoma brucei unspecified product 0.0053 0.0871 0.2809
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0223 0.0655
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0047 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0025 0.0361 0.0967
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.046
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0047 0.0059
Onchocerca volvulus 0.0012 0.014 0.0355
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0047 0.0059
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0249 0.0837
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0047 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0012 0.014 0.046
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0171 0.2978 0.2955
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0012 0.014 0.046
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0241 0.0659
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0047 0.0145
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0013 0.0157 0.0516
Leishmania major small ubiquitin protein, putative 0.003 0.0456 0.1514
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0047 0.0059
Onchocerca volvulus 0.0012 0.014 0.0355
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0025 0.0361 0.1212
Schistosoma mansoni carbonyl reductase 0.0012 0.014 0.0189
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.1565 0.2118
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Leishmania major hypothetical protein, conserved 0.0025 0.0361 0.1195
Echinococcus multilocularis Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0013 0.0157 0.0172
Brugia malayi Retinol dehydrogenase 12 0.0012 0.014 0.0355
Echinococcus granulosus Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0013 0.0157 0.0172
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0012 0.014 0.0373
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0009 0.0077 0.0146
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0081 0.0066
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0077 0.0061
Entamoeba histolytica phosphoinositide kinase, putative 0.0013 0.0157 0.0157
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Schistosoma mansoni hypothetical protein 0.034 0.6007 0.8267
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.046
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0522 0.0491
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0249 0.0218
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Mycobacterium ulcerans phosphoglycerate kinase 0.0171 0.2978 1
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0013 0.0157 0.0516
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.014 0.0373
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0249 0.0582
Loa Loa (eye worm) pip kinase 2 0.0163 0.2841 0.9281
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0127 0.0095
Trichomonas vaginalis dullard protein, putative 0.0025 0.0361 0.0329
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0871 0.2809
Entamoeba histolytica hypothetical protein 0.0036 0.0568 0.0568
Trypanosoma brucei chrX additional, unordered contigs 0.0024 0.0349 0.103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0039 0.0007
Giardia lamblia Phosphoglycerate kinase 0.0171 0.2978 1
Echinococcus granulosus phosphoglycerate kinase 1 0.0171 0.2978 0.4072
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0077 0.0146
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0012 0.014 0.0373
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0348 0.1152
Plasmodium vivax phosphoglycerate kinase, putative 0.0171 0.2978 1
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0081 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0039 0.0007
Schistosoma mansoni terminal deoxycytidyl transferase 0.0077 0.1297 0.1782
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0077 0.1297 0.4299
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.014 0.0355
Echinococcus multilocularis oxidoreductase 0.0012 0.014 0.0149
Leishmania major short chain dehydrogenase/reductase, putative 0.0012 0.014 0.0452
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0012 0.014 0.0316
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0013 0.0157 0.0508
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.1565 0.215
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0348 0.1026
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0871 0.2809
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Loa Loa (eye worm) hypothetical protein 0.0153 0.2655 0.8673
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.0349 0.103
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0039 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Onchocerca volvulus 0.0009 0.0077 0.0146
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0012 0.014 0.0316
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.014 0.0452
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.014 0.0452
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.014 0.0373
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0249 0.0689
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Loa Loa (eye worm) SMO-1 protein 0.003 0.0456 0.148
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0024 0.0349 0.1163
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0051 0.0025
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0568 0.0741
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.014 0.0108
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0082 0.0258
Schistosoma mansoni DNA helicase recq1 0.0009 0.0081 0.0107
Entamoeba histolytica hypothetical protein 0.0036 0.0568 0.0568
Leishmania major phosphoglycerate kinase C, glycosomal 0.0171 0.2978 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0356 0.1153
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0012 0.014 0.0149
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0127 0.0272
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0348 0.1026
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0171 0.2978 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.014 0.0108
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Onchocerca volvulus 0.0012 0.014 0.0355
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Echinococcus multilocularis phosphatidylinositol phosphate 5 kinase type III 0.0013 0.0157 0.0172
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0171 0.2978 1
Plasmodium falciparum small ubiquitin-related modifier 0.003 0.0456 0.1393
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0012 0.014 0.046
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0012 0.014 0.0149
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0047 0.0059
Echinococcus granulosus geminin 0.034 0.6007 0.8259
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.014 0.0108
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0013 0.0157 0.0212
Entamoeba histolytica phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0157 0.0157
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.046
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.014 0.014
Leishmania major hypothetical protein, conserved 0.0012 0.014 0.0452
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0077 0.1297 0.1782
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0006 0.0033 0.0099
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Mycobacterium ulcerans oxidoreductase 0.0012 0.014 0.0316
Toxoplasma gondii exonuclease III APE 0.0018 0.0249 0.0828
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.014 0.0452
Loa Loa (eye worm) hypothetical protein 0.0024 0.0349 0.1132
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.1565 0.2118
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0081 0.0261
Schistosoma mansoni DNA polymerase eta 0.0153 0.2655 0.3651
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0012 0.014 0.0108
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.0077 0.0242
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.014 0.0355
Leishmania major 3-keto-dihydrosphingosine reductase 0.0012 0.014 0.0452
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0306 0.0377
Loa Loa (eye worm) hypothetical protein 0.0009 0.0077 0.0242
Trypanosoma brucei small ubiquitin-related modifier 0.003 0.0456 0.1393
Mycobacterium leprae Probable oxidoreductase 0.0012 0.014 0.0316
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.046
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0013 0.0157 0.0373
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Echinococcus granulosus carbonyl reductase 1 0.0012 0.014 0.0149
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0047 0.014
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.014 0.0149
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0047 0.0059
Echinococcus granulosus oxidoreductase 0.0012 0.014 0.0149
Schistosoma mansoni hypothetical protein 0.034 0.6007 0.8267
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0081 0.0066
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0349 0.103
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0361 0.0329
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0025 0.0361 0.0454
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0012 0.014 0.0316
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0361 0.0329
Leishmania major oxidoreductase-like protein 0.0012 0.014 0.0452
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.014 0.0452
Giardia lamblia DNA damage repair protein 0.0024 0.0349 0.0927
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0012 0.014 0.0448
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.1565 0.215
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0508 0.169
Trypanosoma cruzi hypothetical protein 0.0006 0.0033 0.0099
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0127 0.0127
Brugia malayi Dehydrogenases, short chain protein 2 0.0012 0.014 0.0355
Loa Loa (eye worm) oxidoreductase 0.0012 0.014 0.0448
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.014 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0871 0.2809
Brugia malayi Pip kinase protein 1 0.0013 0.0157 0.041
Echinococcus multilocularis geminin 0.034 0.6007 0.8259
Loa Loa (eye worm) hypothetical protein 0.0024 0.0348 0.1129
Trichomonas vaginalis rotamase, putative 0.0034 0.0522 0.0491
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0006 0.0033 0.0041
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.014 0.0149
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0249 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0039 0.0007
Schistosoma mansoni phosphoglycerate kinase 0.0171 0.2978 0.4096
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.014 0.0373
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0047 0.0149
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Schistosoma mansoni hypothetical protein 0.0024 0.0356 0.0485
Loa Loa (eye worm) dehydrogenase 0.0012 0.014 0.0448
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0157 0.0516
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0249 0.0249
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0077 0.0061
Loa Loa (eye worm) hypothetical protein 0.0009 0.0077 0.0242
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.1016 0.1395
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.003 0.0456 0.0623
Echinococcus granulosus steroid dehydrogenase 0.0012 0.014 0.0149
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0348 0.1026
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.014 0.0108
Trypanosoma brucei phosphoglycerate kinase, putative 0.0063 0.1044 0.3401
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0025 0.0361 0.0493
Leishmania major hypothetical protein, conserved 0.0012 0.014 0.0452
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0013 0.0157 0.0508
Plasmodium vivax hypothetical protein, conserved 0.0012 0.014 0.047
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0012 0.014 0.0355
Brugia malayi polk-prov protein 0.0024 0.0349 0.1046
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.1044 0.3499
Loa Loa (eye worm) hypothetical protein 0.0017 0.0228 0.0736
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0047 0.0149
Trichomonas vaginalis dullard protein, putative 0.0025 0.0361 0.0329
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0241 0.0714
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0171 0.2978 1
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0182 0.0609
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0012 0.014 0.0373
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0438 0.1423
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0348 0.0348
Schistosoma mansoni ras GTP exchange factor 0.0006 0.0033 0.0041
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Loa Loa (eye worm) oxidoreductase 0.0012 0.014 0.0448
Chlamydia trachomatis phosphoglycerate kinase 0.0171 0.2978 1
Onchocerca volvulus 0.001 0.0109 0.0252
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Brugia malayi hypothetical protein 0.0036 0.0568 0.177
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0077 0.0102
Entamoeba histolytica phosphoglycerate kinase, putative 0.0171 0.2978 0.2978
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0077 0.0146
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.014 0.046
Echinococcus granulosus cpg binding protein 0.003 0.0467 0.0601
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0007 0.0047 0.0149
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0508 0.0508
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0249 0.03
Leishmania major short chain dehydrogenase, putative 0.0012 0.014 0.0452
Loa Loa (eye worm) RecQ helicase 0.0021 0.0306 0.0989
Brugia malayi Ubiquitin-like protein SMT3 0.003 0.0456 0.1397
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0105 0.0196
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0012 0.014 0.0373
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.014 0.0316
Onchocerca volvulus Sepiapterin reductase homolog 0.0012 0.014 0.0355
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0105 0.0342
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0361 0.0329
Brugia malayi hypothetical protein 0.0009 0.0077 0.0146
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0012 0.014 0.046
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0012 0.014 0.046
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0348 0.1152
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Schistosoma mansoni carbonyl reductase 0.0012 0.014 0.0189
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0013 0.0157 0.0508
Loa Loa (eye worm) oxidoreductase 0.0012 0.014 0.0448
Schistosoma mansoni hypothetical protein 0.0411 0.7266 1
Brugia malayi hypothetical protein 0.0012 0.014 0.0355
Mycobacterium ulcerans hypothetical protein 0.0024 0.0349 0.103
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0563 1 1
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.014 0.0316
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.1044 0.3499
Plasmodium falciparum steroid dehydrogenase, putative 0.0012 0.014 0.0316
Brugia malayi Dehydrogenases, short chain protein 30 0.0012 0.014 0.0355
Mycobacterium ulcerans dehydrogenase 0.0012 0.014 0.0316
Plasmodium falciparum phosphoglycerate kinase 0.0171 0.2978 1
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0171 0.2978 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Entamoeba histolytica hypothetical protein 0.001 0.0109 0.0109
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.0349 0.1163
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0522 0.1617
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0077 0.0061
Entamoeba histolytica hypothetical protein 0.0036 0.0568 0.0568
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0249 0.0828
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.0077 0.0242
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.014 0.0108
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0012 0.014 0.046
Loa Loa (eye worm) hypothetical protein 0.0018 0.0241 0.0777
Loa Loa (eye worm) hypothetical protein 0.0024 0.0348 0.1129
Loa Loa (eye worm) hypothetical protein 0.001 0.0109 0.0347
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0348 0.0348
Echinococcus multilocularis dna polymerase kappa 0.0077 0.1297 0.1749
Giardia lamblia Sentrin 0.003 0.0456 0.1295
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0047 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0077 0.1297 0.4345
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0163 0.2841 0.3882
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0081 0.0066
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.1565 0.2118
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0006 0.0027 0.0033
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0077 0.0061
Loa Loa (eye worm) hypothetical protein 0.0018 0.0241 0.0777
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0025 0.0361 0.0454
Onchocerca volvulus 0.0163 0.2841 0.9274
Trichomonas vaginalis steroid dehydrogenase, putative 0.0012 0.014 0.0108
Loa Loa (eye worm) hypothetical protein 0.0083 0.1405 0.4586
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0012 0.014 0.0373
Giardia lamblia Hypothetical protein 0.0013 0.0157 0.0263
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0249 0.0503
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.046
Giardia lamblia Short-chain dehydrogenase, putative 0.0012 0.014 0.0205
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0348 0.1026
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.014 0.046
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0051 0.0025
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0241 0.0659
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Entamoeba histolytica hypothetical protein 0.0036 0.0568 0.0568
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Loa Loa (eye worm) RasGEF domain-containing protein 0.0006 0.0033 0.0096
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0249 0.0689
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0013 0.0157 0.0212
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0077 0.0061
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0051 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0241 0.0777
Onchocerca volvulus 0.0012 0.014 0.0355
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.014 0.0316
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0249 0.0828
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.014 0.0149
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0105 0.0333
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0039 0.0007
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0024 0.0349 0.1163
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0047 0.0059
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0077 0.0061
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Schistosoma mansoni carbonyl reductase 0.0012 0.014 0.0189
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.1044 0.3499
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0081 0.0066
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0012 0.014 0.046
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0012 0.014 0.0316
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0241 0.0808
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0013 0.0157 0.041
Echinococcus multilocularis conserved hypothetical protein 0.0012 0.014 0.0149
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.014 0.014
Trypanosoma cruzi DNA polymerase eta, putative 0.0153 0.2655 0.8914
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0249 0.0819
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0047 0.0049
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0012 0.014 0.0316
Loa Loa (eye worm) oxidoreductase 0.0012 0.014 0.0448
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0012 0.014 0.0355
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.014 0.0108
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0012 0.014 0.0123
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.014 0.014
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0006 0.0033 0.0041
Trypanosoma cruzi small ubiquitin protein, putative 0.003 0.0456 0.1522
Echinococcus multilocularis transient receptor potential cation channel 0.0012 0.014 0.0149
Loa Loa (eye worm) oxidoreductase 0.0012 0.014 0.0448
Giardia lamblia Reductase, putative 0.0012 0.014 0.0205
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0047 0.0021
Brugia malayi Phosphoglycerate kinase 0.0171 0.2978 0.9727
Onchocerca volvulus 0.0012 0.014 0.0355
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0012 0.014 0.0205
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.014 0.0373
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Loa Loa (eye worm) hypothetical protein 0.0009 0.0077 0.0242
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0039 0.0007
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0508 0.1697
Leishmania major pteridine reductase 1 0.0012 0.014 0.0452
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0077 0.0102
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.014 0.0316
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Schistosoma mansoni dishevelled 0.0009 0.0077 0.0102
Entamoeba histolytica recQ family DNA helicase 0.0005 0.0003 0.0003
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0083 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.014 0.0149
Loa Loa (eye worm) oxidoreductase 0.0012 0.014 0.0448
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0163 0.2841 0.3907
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0012 0.014 0.046
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0039 0.0007
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.1044 0.3499
Brugia malayi N-terminal motif family protein 0.0175 0.3061 1
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.1297 0.4265
Onchocerca volvulus 0.0012 0.014 0.0355
Schistosoma mansoni hypothetical protein 0.0036 0.0568 0.0778
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0249 0.0806
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0306 0.0274
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0348 0.0348
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0157 0.0516
Trypanosoma brucei phosphoglycerate kinase 0.0171 0.2978 1
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0012 0.014 0.0373
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0013 0.0157 0.0212
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.014 0.0373
Schistosoma mansoni dishevelled 0.0009 0.0077 0.0102
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.014 0.0316
Echinococcus multilocularis expressed protein 0.0034 0.0522 0.0677
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0348 0.1026
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0508 0.1697
Schistosoma mansoni DNA helicase recq5 0.0009 0.0081 0.0107
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0007 0.0047 0.0047
Trypanosoma cruzi small ubiquitin protein, putative 0.003 0.0456 0.1522
Trypanosoma cruzi short chain dehydrogenase, putative 0.0012 0.014 0.046
Toxoplasma gondii small ubiquitin family modifier, putative 0.003 0.0456 0.1522
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0025 0.0361 0.1212
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0013 0.0157 0.0516
Onchocerca volvulus 0.0012 0.014 0.0355
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0249 0.0828
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.0349 0.103
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.014 0.0149
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.014 0.0108
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.014 0.0316
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0039 0.0007
Echinococcus multilocularis 0.0025 0.0361 0.0454
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0157 0.0526
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0012 0.014 0.0373
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.014 0.0316
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0077 0.0061
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0077 0.0061
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.1044 0.3493
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0047 0.0049
Leishmania major hypothetical protein, conserved 0.0012 0.014 0.0452
Onchocerca volvulus 0.0029 0.0438 0.1339
Loa Loa (eye worm) hypothetical protein 0.0007 0.0047 0.0145
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0012 0.014 0.046
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0047 0.0145
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0025 0.0361 0.0361
Plasmodium vivax acetyl-CoA synthetase, putative 0.0007 0.0047 0.0159
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0012 0.014 0.0316
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0013 0.0157 0.0516
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.1297 0.4265
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0249 0.0716
Trypanosoma brucei DNA polymerase eta, putative 0.0153 0.2655 0.8897
Mycobacterium ulcerans short-chain type oxidoreductase 0.0012 0.014 0.0316
Echinococcus granulosus carbonyl reductase 1 0.0012 0.014 0.0149
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0568 0.0741
Echinococcus multilocularis ubiquitin 0.001 0.0109 0.0106
Plasmodium vivax small ubiquitin-related modifier, putative 0.003 0.0456 0.153
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0039 0.0007
Echinococcus multilocularis retinol dehydrogenase 13 0.0012 0.014 0.0149
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0047 0.0061
Loa Loa (eye worm) hypothetical protein 0.0006 0.0033 0.0096
Onchocerca volvulus 0.0012 0.014 0.0355
Echinococcus granulosus dnaJ subfamily B 0.0411 0.7266 1
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0063 0.1044 0.3499
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0012 0.014 0.0108
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0127 0.0417
Entamoeba histolytica hypothetical protein 0.0006 0.0033 0.0033
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0171 0.2978 0.2955
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0163 0.2841 0.3882
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0077 0.1297 0.1749
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0012 0.014 0.0189
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0157 0.0373
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0047 0.0059
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0012 0.014 0.0373
Mycobacterium tuberculosis Possible oxidoreductase 0.0012 0.014 0.0373
Entamoeba histolytica hypothetical protein 0.0012 0.014 0.014
Echinococcus granulosus ubiquitin 0.001 0.0109 0.0106
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0006 0.0033 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.014 0.046
Brugia malayi dehydrogenases, short chain protein 9 0.0012 0.014 0.0355
Mycobacterium ulcerans hypothetical protein 0.0024 0.0348 0.1026
Giardia lamblia Hypothetical protein 0.0012 0.014 0.0205
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0348 0.1042
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0225 0.0306
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0508 0.1697
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0012 0.014 0.0355
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0047 0.014
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0013 0.0157 0.0516
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0249 0.03
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0012 0.014 0.046
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0012 0.014 0.046
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0077 0.0061
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.014 0.0316
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0081 0.0113
Schistosoma mansoni DNA polymerase IV / kappa 0.0024 0.0349 0.0477
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0081 0.0159
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0361 0.0329
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0081 0.0159
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0047 0.0015
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0157 0.0516
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0012 0.014 0.046
Leishmania major phosphoglycerate kinase B, cytosolic 0.0171 0.2978 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0105 0.0342
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0006 0.0033 0.0041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0348 0.1042
Echinococcus granulosus hypothetical protein 0.0012 0.014 0.0149
Echinococcus granulosus CTD small phosphatase protein like 0.0025 0.0361 0.0454
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Entamoeba histolytica ubiquitin like protein 0.003 0.0456 0.0456
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.014 0.046
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Leishmania major dehydrogenase-like protein 0.0012 0.014 0.0452
Mycobacterium ulcerans DNA polymerase IV 0.0077 0.1297 0.4265
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0039 0.0007
Toxoplasma gondii carbonyl reductase 1, putative 0.0012 0.014 0.046
Onchocerca volvulus 0.0012 0.014 0.0355
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.014 0.0373
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Onchocerca volvulus 0.0007 0.0047 0.0049
Loa Loa (eye worm) pip kinase 1 0.0013 0.0157 0.0502
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0012 0.014 0.0149
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.014 0.0316
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.014 0.0316
Brugia malayi hypothetical protein 0.0009 0.0077 0.0146
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0013 0.0157 0.0502
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.014 0.0355
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0012 0.014 0.0316
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0012 0.014 0.0189
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0223 0.0655
Schistosoma mansoni retinal dehydrogenase 0.0012 0.014 0.0189
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Schistosoma mansoni steroid dehydrogenase 0.0012 0.014 0.0189
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0012 0.014 0.0373
Schistosoma mansoni short chain dehydrogenase 0.0012 0.014 0.0189
Loa Loa (eye worm) hypothetical protein 0.0012 0.014 0.0448
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0051 0.0025
Echinococcus granulosus bloom syndrome protein 0.0021 0.0306 0.0377

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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