Detailed information for compound 273821

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 621.81 | Formula: C35H51N5O5
  • H donors: 6 H acceptors: 5 LogP: 4.42 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 3
  • SMILES: O=C1NCCCCC(NC(=O)C(Cc2ccccc2)N)C(=O)NC(C(=O)NCC1)Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C
  • InChi: 1S/C35H51N5O5/c1-34(2,3)24-18-23(19-25(30(24)42)35(4,5)6)21-28-32(44)38-17-15-29(41)37-16-11-10-14-27(33(45)40-28)39-31(43)26(36)20-22-12-8-7-9-13-22/h7-9,12-13,18-19,26-28,42H,10-11,14-17,20-21,36H2,1-6H3,(H,37,41)(H,38,44)(H,39,43)(H,40,45)
  • InChiKey: VMJSQTCIMVQDGV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.008 0.0096 0.0245
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0035 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0104 0.0138 0.0361
Trichomonas vaginalis inositol monophosphatase, putative 0.0029 0.0005 0.0076
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0032 0.001 0.0023
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.004 0.0026 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0006 0.0088
Echinococcus multilocularis biogenic amine (5HT) receptor 0.4124 0.7233 1
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0852 0.1458 1
Echinococcus granulosus cpg binding protein 0.0033 0.0014 0.0017
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0108 0.0146 0.0199
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0101 0.0133 0.035
Loa Loa (eye worm) MH2 domain-containing protein 0.039 0.0643 0.1704
Brugia malayi AMP-binding enzyme family protein 0.0032 0.001 0.0023
Onchocerca volvulus 0.0145 0.021 0.1303
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0078 0.0093 0.0243
Onchocerca volvulus 0.0033 0.0014 0.0073
Echinococcus multilocularis g-protein coupled receptor 0.0145 0.021 0.0289
Mycobacterium tuberculosis Conserved protein 0.0148 0.0216 0.0548
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0035 0.0016 0.0037
Echinococcus multilocularis mitogen activated protein kinase 3 0.0113 0.0154 0.0211
Leishmania major hypothetical protein, conserved 0.0075 0.0087 0.0219
Echinococcus granulosus rhodopsin orphan GPCR 0.0145 0.021 0.0289
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0336 0.0547 0.145
Schistosoma mansoni hypothetical protein 0.0081 0.0099 0.0097
Loa Loa (eye worm) hypothetical protein 0.0396 0.0654 0.1734
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0202 0.0311 0.0428
Onchocerca volvulus 0.0145 0.021 0.1303
Plasmodium vivax metacaspase 1, putative 0.0029 0.0006 0.0013
Trypanosoma cruzi metacaspase, putative 0.0029 0.0006 0.0015
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0852 0.1458 1
Echinococcus granulosus nAChR subunit 0.0104 0.0137 0.0188
Schistosoma mansoni myosin xvIII 0.0145 0.021 0.0209
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0006 0.0009
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.001 0.0026
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Echinococcus granulosus neuropeptides capa receptor 0.0145 0.021 0.0289
Loa Loa (eye worm) hypothetical protein 0.025 0.0396 0.1047
Mycobacterium ulcerans hypothetical protein 0.0078 0.0093 0.0604
Echinococcus granulosus tar DNA binding protein 0.0071 0.008 0.0108
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.001 0.0026
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0116 0.0159 0.1061
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0078 0.0093 0.0689
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0145 0.021 0.0209
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0316 0.0512 0.2129
Schistosoma mansoni tyrosine kinase 0.0087 0.0109 0.0107
Echinococcus granulosus peptidase Clp S14 family 0.0076 0.0089 0.0121
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0042 0.0109
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.023 0.036 0.0954
Mycobacterium tuberculosis Conserved hypothetical protein 0.0077 0.009 0.0229
Loa Loa (eye worm) TK/INSR protein kinase 0.0052 0.0047 0.0122
Loa Loa (eye worm) neuropeptide F receptor 0.0145 0.021 0.0555
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0078 0.0093 0.0379
Plasmodium vivax hypothetical protein, conserved 0.0148 0.0216 0.0762
Trichomonas vaginalis D-aminoacylase, putative 0.0148 0.0216 0.5164
Onchocerca volvulus 0.0585 0.0988 0.617
Echinococcus granulosus neuropeptide FF receptor 2 0.0145 0.021 0.0289
Echinococcus granulosus glutaminyl peptide cyclotransferase 0.0932 0.16 0.221
Brugia malayi beta-lactamase 0.0148 0.0216 0.057
Echinococcus granulosus dro:myosuppressin receptor 0.0145 0.021 0.0289
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0145 0.021 0.0289
Trypanosoma brucei DNA polymerase eta, putative 0.0105 0.0141 0.0355
Onchocerca volvulus Fxna peptidase homolog 0.0148 0.0217 0.1342
Echinococcus granulosus histone acetyltransferase KAT2B 0.0155 0.0229 0.0314
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.009 0.0226
Loa Loa (eye worm) hypothetical protein 0.025 0.0396 0.1047
Entamoeba histolytica hypothetical protein 0.0191 0.0292 0.464
Echinococcus granulosus dnaJ subfamily B 0.045 0.075 0.1035
Onchocerca volvulus 0.0585 0.0988 0.617
Echinococcus multilocularis G protein coupled receptor 139 0.0145 0.021 0.0289
Brugia malayi hypothetical protein 0.0098 0.0128 0.0336
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0098 0.0128 0.0336
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0032 0.001 0.0035
Brugia malayi MAP kinase sur-1 0.0113 0.0154 0.0406
Trichomonas vaginalis Clan MH, family M28, aminopeptidase S-like metallopeptidase 0.0148 0.0217 0.5176
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0128 0.0175
Loa Loa (eye worm) hypothetical protein 0.0148 0.0217 0.0571
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0035 0.0016 0.0037
Toxoplasma gondii 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein 0.0078 0.0093 0.0233
Loa Loa (eye worm) hypothetical protein 0.0035 0.0016 0.0037
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0035 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni biogenic amine receptor 0.0145 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0098 0.0128 0.0336
Schistosoma mansoni neuropeptide f receptor 76f 0.0145 0.021 0.0209
Mycobacterium ulcerans beta-lactamase 0.0148 0.0216 0.1451
Loa Loa (eye worm) G-protein coupled receptor 0.0145 0.021 0.0555
Schistosoma mansoni caspase-7 (C14 family) 0.0108 0.0146 0.0144
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0011 0.0024
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0032 0.001 0.0029
Chlamydia trachomatis dihydrolipoamide acetyltransferase 0.0078 0.0093 0.0689
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.012 0.0493
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.007 0.0173
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0202 0.0311 0.0822
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0107 0.0144 0.0957
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni opsin-like receptor 0.0145 0.021 0.0209
Plasmodium vivax lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative 0.0078 0.0093 0.0323
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0104 0.0137 0.0361
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0202 0.0311 0.0428
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0016 0.0037
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0038 0.0091
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Leishmania major carboxylase, putative 0.0852 0.1458 0.3734
Brugia malayi Dopamine receptor 0.0145 0.021 0.0555
Schistosoma mansoni adenoreceptor 0.0145 0.021 0.0209
Schistosoma mansoni transcription factor LCR-F1 0.0191 0.0292 0.0291
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0032 0.001 0.0034
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.0302 0.08
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0076 0.009 0.0227
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0145 0.021 0.0209
Trypanosoma brucei unspecified product 0.0077 0.009 0.0226
Trypanosoma cruzi metacaspase 5, putative 0.0029 0.0006 0.0015
Schistosoma mansoni opsin-like receptor 0.0145 0.021 0.0209
Loa Loa (eye worm) twinkle helicase 0.0074 0.0085 0.0221
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0116 0.0159 0.1094
Echinococcus multilocularis dna polymerase eta 0.0105 0.0141 0.0192
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0336 0.0547 0.145
Brugia malayi larval opioid receptor 0.0145 0.021 0.0555
Echinococcus multilocularis rhodopsin orphan GPCR 0.0145 0.021 0.0289
Loa Loa (eye worm) steroid hormone receptor 0.0035 0.0016 0.0037
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0145 0.021 0.0289
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0154 0.3673
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.001 0.0035
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0032 0.001 0.0034
Onchocerca volvulus 0.0145 0.021 0.1303
Schistosoma mansoni caspase-3 (C14 family) 0.0108 0.0146 0.0144
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.004 0.0025 0.0173
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0116 0.0159 0.3496
Mycobacterium leprae Probable lipase LipE 0.0148 0.0216 0.1482
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0035 0.0016 0.0037
Trichomonas vaginalis DNA polymerase eta, putative 0.0077 0.009 0.2131
Echinococcus granulosus biogenic amine 5HT receptor 0.4124 0.7233 1
Loa Loa (eye worm) hypothetical protein 0.0197 0.0302 0.08
Loa Loa (eye worm) hypothetical protein 0.0336 0.0547 0.145
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0077 0.009 0.2131
Echinococcus granulosus g-protein coupled receptor 0.0145 0.021 0.0289
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni hypothetical protein 0.0145 0.021 0.0209
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0202 0.0311 0.0309
Leishmania major 4-coumarate:coa ligase-like protein 0.0107 0.0144 0.0365
Echinococcus multilocularis protein dispatched 1 0.0096 0.0125 0.0171
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0035 0.0016 0.0019
Echinococcus multilocularis FTZ F1 alpha 0.0035 0.0016 0.0019
Plasmodium falciparum acyl-CoA synthetase 0.008 0.0096 0.0336
Loa Loa (eye worm) hypothetical protein 0.0035 0.0016 0.0037
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0257 0.0409 0.278
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0032 0.001 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.001 0.0035
Schistosoma mansoni acetylcholine receptor subunit beta 0.0098 0.0128 0.0126
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0145 0.021 0.0555
Brugia malayi putative neuropeptide receptor NPR1 0.0145 0.021 0.0555
Loa Loa (eye worm) hypothetical protein 0.0078 0.0093 0.0243
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.2236 0.3902 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0107 0.0144 0.0957
Loa Loa (eye worm) hypothetical protein 0.0336 0.0547 0.145
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0202 0.0311 0.0822
Schistosoma mansoni amine GPCR 0.0145 0.021 0.0209
Brugia malayi Cation transporter family protein 0.0202 0.0311 0.0822
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0148 0.0217 0.0297
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0083 0.0207
Onchocerca volvulus Fxna peptidase homolog 0.0148 0.0217 0.1342
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.2258 0.394 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0035 0.0016 0.0019
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.0023 0.0053
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.2072 0.3613 0.9169
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Mycobacterium ulcerans DNA polymerase IV 0.0077 0.009 0.0586
Toxoplasma gondii pyruvate carboxylase 0.0852 0.1458 0.3734
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0035 0.0016 0.0037
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0116 0.0159 0.056
Loa Loa (eye worm) hypothetical protein 0.0104 0.0137 0.0361
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0042 0.0109
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0081 0.0097 0.0255
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0145 0.021 0.0209
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0145 0.021 0.0209
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0035 0.0016 0.0037
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0145 0.021 0.0209
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0042 0.0109
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0078 0.0093 0.0243
Brugia malayi Inositol-1 0.0029 0.0005 0.001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.0302 0.4799
Schistosoma mansoni cpg binding protein 0.0033 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0034 0.0014 0.0033
Schistosoma mansoni tyrosine kinase 0.0088 0.011 0.0109
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0098 0.0128 0.0336
Echinococcus granulosus sentrin specific protease 8 0.0027 0.0002 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0094 0.012 0.0493
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.009 0.0226
Onchocerca volvulus 0.0585 0.0988 0.617
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0078 0.0093 0.0126
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0202 0.0311 0.0822
Mycobacterium leprae conserved hypothetical protein 0.0148 0.0216 0.1482
Brugia malayi Cation transporter family protein 0.0202 0.0311 0.0822
Echinococcus granulosus expressed conserved protein 0.0185 0.0281 0.0387
Loa Loa (eye worm) TK/EGFR protein kinase 0.0164 0.0245 0.0646
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0018 0.0044
Brugia malayi beta-NAC-like protein 0.0039 0.0023 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0016 0.0037
Toxoplasma gondii MAPEG family protein 0.0123 0.0172 0.0436
Schistosoma mansoni inositol monophosphatase 0.0029 0.0005 0.0004
Trypanosoma brucei membrane transporter protein, putative 0.0075 0.0087 0.0219
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0077 0.009 0.0123
Plasmodium vivax acetyl-CoA synthetase, putative 0.0032 0.001 0.0029
Onchocerca volvulus 0.0148 0.0216 0.1339
Brugia malayi TAR-binding protein 0.0071 0.008 0.0208
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0303 0.049 0.125
Treponema pallidum replicative DNA helicase (dnaB) 0.0257 0.0409 1
Echinococcus multilocularis fmrfamide receptor 0.0145 0.021 0.0289
Entamoeba histolytica acyl-coA synthetase, putative 0.0107 0.0144 0.2272
Loa Loa (eye worm) hypothetical protein 0.0877 0.1503 0.3991
Onchocerca volvulus 0.0585 0.0988 0.617
Leishmania major glutaminyl cyclase, putative 0.0148 0.0217 0.055
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Plasmodium falciparum glutathione reductase 0.0033 0.0014 0.0042
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.012 0.0493
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0032 0.001 0.0071
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0202 0.0311 0.0309
Echinococcus multilocularis neuropeptide s receptor 0.0651 0.1105 0.1525
Onchocerca volvulus Protein ultraspiracle homolog 0.0035 0.0016 0.0084
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Loa Loa (eye worm) hypothetical protein 0.005 0.0042 0.0109
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0116 0.0159 0.1061
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0148 0.0217 0.0297
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0035 0.0016 0.0014
Brugia malayi Cation transporter family protein 0.0202 0.0311 0.0822
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0032 0.001 0.0026
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0316 0.0512 0.1308
Brugia malayi Dopamine receptor protein 2 0.0145 0.021 0.0555
Brugia malayi Carboxyl transferase domain containing protein 0.2158 0.3764 1
Trypanosoma cruzi hypothetical protein, conserved 0.0148 0.0216 0.0893
Schistosoma mansoni neuropeptide F-like receptor 0.0145 0.021 0.0209
Chlamydia trachomatis acetyl-CoA carboxylase biotin carboxyl carrier protein 0.0078 0.0093 0.0689
Onchocerca volvulus 0.0034 0.0014 0.0074
Trypanosoma brucei dihydrolipoamide acetyltransferase E2 subunit, putative 0.0078 0.0093 0.0233
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0148 0.0216 0.057
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0145 0.021 0.0555
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0107 0.0144 0.0957
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0032 0.001 0.0035
Schistosoma mansoni cpg binding protein 0.0033 0.0014 0.0012
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0005 0.0008
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0145 0.021 0.0289
Echinococcus granulosus glycine receptor subunit alpha 1 0.0202 0.0311 0.0428
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0098 0.0128 0.0336
Echinococcus granulosus rhodopsin orphan GPCR 0.0145 0.021 0.0289
Loa Loa (eye worm) neuropeptide F receptor 0.0145 0.021 0.0555
Schistosoma mansoni biogenic amine (5HT) receptor 0.4124 0.7233 0.7232
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0078 0.0093 0.0091
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0032 0.001 0.0035
Schistosoma mansoni peptidase Clp (S14 family) 0.0116 0.0159 0.0158
Trichomonas vaginalis D-aminoacylase, putative 0.0148 0.0216 0.5164
Echinococcus granulosus nAChR subunit 0.0202 0.0311 0.0428
Schistosoma mansoni hypothetical protein 0.0145 0.021 0.0209
Onchocerca volvulus Cell death protein 3 homolog 0.0029 0.0006 0.0023
Schistosoma mansoni nAChR subunit 0.0202 0.0311 0.0309
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0038 0.0855
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0076 0.009 0.0227
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.016 0.0236 0.0325
Echinococcus granulosus glycine receptor subunit alpha 1 0.0202 0.0311 0.0428
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E2 0.0078 0.0093 0.0233
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0076 0.0089 0.0226
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0148 0.0217 0.0297
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0016 0.0037
Toxoplasma gondii biotin-requiring enzyme domain-containing protein 0.0078 0.0093 0.0233
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0082 0.0099 0.0135
Echinococcus multilocularis cpg binding protein 0.0033 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0202 0.0311 0.0822
Onchocerca volvulus 0.0107 0.0144 0.089
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.009 0.0368
Loa Loa (eye worm) hypothetical protein 0.0035 0.0016 0.0037
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0104 0.0137 0.0361
Brugia malayi AMP-binding enzyme family protein 0.0032 0.001 0.0023
Brugia malayi hypothetical protein 0.0396 0.0654 0.1734
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0202 0.0311 0.0428
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Trypanosoma brucei unspecified product 0.056 0.0943 0.2413
Loa Loa (eye worm) hypothetical protein 0.004 0.0026 0.0065
Trypanosoma brucei membrane transporter protein, putative 0.0075 0.0087 0.0219
Echinococcus multilocularis dnaJ subfamily B 0.045 0.075 0.1035
Echinococcus multilocularis mitogen activated protein kinase 11 0.014 0.0202 0.0277
Plasmodium vivax SET domain protein, putative 0.0034 0.0014 0.0042
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0202 0.0311 0.0428
Echinococcus granulosus dna polymerase eta 0.0105 0.0141 0.0192
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0078 0.0093 0.0379
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0098 0.0128 0.0336
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0014 0.003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.009 0.0368
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0027 0.0002 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0038 0.005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0077 0.009 0.0229
Schistosoma mansoni nAChR subunit 0.0202 0.0311 0.0309
Mycobacterium ulcerans DNA polymerase IV 0.0077 0.009 0.0586
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0087 0.0356
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0113 0.0154 0.0635
Brugia malayi RE15519p 0.0145 0.021 0.0555
Leishmania major mitochondrial DNA polymerase beta 0.0667 0.1133 0.2899
Schistosoma mansoni hypothetical protein 0.0191 0.0292 0.0291
Trypanosoma brucei glutaminyl cyclase, putative 0.0148 0.0217 0.055
Loa Loa (eye worm) ACC-1 protein 0.0202 0.0311 0.0822
Onchocerca volvulus 0.0032 0.001 0.0052
Echinococcus multilocularis expressed conserved protein 0.0185 0.0281 0.0387
Echinococcus granulosus tm gpcr rhodopsin 0.1063 0.183 0.2529
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0852 0.1458 0.3734
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.2236 0.3902 0.5394
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0145 0.021 0.0209
Brugia malayi hypothetical protein 0.0098 0.0128 0.0336
Trichomonas vaginalis antibiotic synthetase, putative 0.0032 0.001 0.0199
Loa Loa (eye worm) hypothetical protein 0.0107 0.0144 0.0379
Onchocerca volvulus Bile acid receptor homolog 0.0035 0.0016 0.0084
Brugia malayi Cell death protein 3 precursor 0.0029 0.0006 0.0011
Onchocerca volvulus Huntingtin homolog 0.0122 0.017 0.1053
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.004 0.0026 0.0034
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0202 0.0311 0.0428
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0145 0.021 0.0289
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.004 0.0026 0.0034
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0303 0.049 0.3333
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0148 0.0216 0.0214
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.014 0.0202 0.0512
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0193 0.0295 0.0293
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0538 0.0904 0.0902
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0029 0.0005 0.0076
Loa Loa (eye worm) hypothetical protein 0.025 0.0396 0.1047
Echinococcus granulosus caspase 8 0.0029 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0029 0.0038
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0078 0.0093 0.0379
Plasmodium vivax dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative 0.0078 0.0093 0.0323
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.2158 0.3764 1
Echinococcus granulosus dna polymerase kappa 0.0077 0.009 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0217 0.5176
Echinococcus granulosus glycine receptor subunit alpha 1 0.0202 0.0311 0.0428
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0032 0.001 0.0034
Brugia malayi G-protein coupled receptor 0.0145 0.021 0.0555
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0202 0.0311 0.0822
Mycobacterium tuberculosis Probable dehydrogenase 0.0076 0.009 0.0227
Echinococcus multilocularis geminin 0.0374 0.0616 0.0849
Trypanosoma cruzi metacaspase, putative 0.0029 0.0006 0.0015
Leishmania major acetyl-CoA synthetase, putative 0.0032 0.001 0.0021
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0006 0.0009
Brugia malayi Cytochrome P450 family protein 0.0036 0.0018 0.0044
Schistosoma mansoni inositol monophosphatase 0.0029 0.0005 0.0004
Echinococcus granulosus ecdysone induced protein 78C 0.0035 0.0016 0.0019
Echinococcus granulosus tm gpcr rhodopsin 0.0145 0.021 0.0289
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0032 0.001 0.0035
Toxoplasma gondii hypothetical protein 0.0148 0.0217 0.055
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0078 0.0093 0.0379
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0104 0.0272
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0113 0.0154 0.0406
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0852 0.1458 0.3734
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0303 0.049 0.3699
Brugia malayi neuropeptide F receptor 0.0145 0.021 0.0555
Schistosoma mansoni coup transcription factor 0.0035 0.0016 0.0014
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0032 0.001 0.0021
Echinococcus multilocularis neuropeptides capa receptor 0.0145 0.021 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0133 0.3167
Plasmodium falciparum dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 0.0078 0.0093 0.0323
Loa Loa (eye worm) hypothetical protein 0.0104 0.0137 0.0361
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0033 0.0014 0.0035
Loa Loa (eye worm) hypothetical protein 0.0034 0.0015 0.0035
Schistosoma mansoni nAChR subunit 0.0202 0.0311 0.0309
Onchocerca volvulus 0.0145 0.021 0.1303
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0381 0.0628 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0128 0.0336
Schistosoma mansoni neuropeptide F-like receptor 0.0145 0.021 0.0209
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0052 0.0047 0.0063
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1618 0.2811 1
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Loa Loa (eye worm) hypothetical protein 0.0148 0.0216 0.057
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0303 0.049 0.3333
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0014 0.0017
Echinococcus granulosus 7tm_1 domain containing protein 0.0145 0.021 0.0289
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0337 0.0549 0.0758
Echinococcus multilocularis neuropeptide Y receptor 0.0145 0.021 0.0289
Mycobacterium tuberculosis Probable lipase LipE 0.0148 0.0216 0.0548
Echinococcus multilocularis rhodopsin orphan GPCR 0.0145 0.021 0.0289
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0078 0.0093 0.0689
Schistosoma mansoni cellular tumor antigen P53 0.0033 0.0014 0.0012
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide acyltransferase E2 component 0.0078 0.0093 0.0604
Trypanosoma brucei MATE efflux family protein, putative 0.0075 0.0087 0.0219
Entamoeba histolytica hypothetical protein 0.0191 0.0292 0.464
Schistosoma mansoni acetyl-CoA synthetase 0.0032 0.001 0.0009
Plasmodium falciparum thioredoxin reductase 0.0033 0.0014 0.0042
Trichomonas vaginalis penicillin-binding protein, putative 0.0148 0.0216 0.5164
Mycobacterium ulcerans branched-chain alpha-keto acid dehydrogenase subunit E2 0.0078 0.0093 0.0604
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Loa Loa (eye worm) hypothetical protein 0.0148 0.0216 0.057
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0145 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni Fxna peptidase (M28 family) 0.0148 0.0217 0.0215
Loa Loa (eye worm) RNA binding protein 0.0071 0.008 0.0208
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Loa Loa (eye worm) acetylcholine receptor protein 0.0098 0.0128 0.0336
Plasmodium vivax acyl-CoA synthetase, putative 0.008 0.0096 0.0336
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.1035 0.1781 0.178
Mycobacterium ulcerans hypothetical protein 0.0352 0.0575 0.3922
Echinococcus granulosus sentrin specific protease 7 0.0308 0.0498 0.0686
Echinococcus multilocularis tumor protein p63 0.0228 0.0358 0.0493
Schistosoma mansoni acetyl-CoA carboxylase 0.2236 0.3902 0.3901
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0145 0.021 0.0555
Onchocerca volvulus 0.0104 0.0137 0.0847
Echinococcus multilocularis glutaminyl peptide cyclotransferase 0.0932 0.16 0.221
Loa Loa (eye worm) hypothetical protein 0.0601 0.1015 0.2694
Echinococcus multilocularis Niemann Pick C1 protein 0.0282 0.0452 0.0622
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0145 0.021 0.0209
Wolbachia endosymbiont of Brugia malayi branched-chain alpha-keto acid dehydrogenase subunit E2 0.0078 0.0093 0.0604
Brugia malayi Pre-SET motif family protein 0.023 0.036 0.0954
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0202 0.0311 0.0822
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0128 0.0175
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0148 0.0217 0.0297
Schistosoma mansoni tyrosine kinase 0.0052 0.0047 0.0046
Brugia malayi AMP-binding enzyme family protein 0.0107 0.0144 0.0379
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0116 0.0159 0.0218
Schistosoma mansoni kinase 0.0052 0.0047 0.0045
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0083 0.0081
Leishmania major dihydrolipoamide acetyltransferase precursorlike protein 0.0078 0.0093 0.0233
Echinococcus granulosus caspase 2 0.0029 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0071 0.008 0.0078
Trichomonas vaginalis antibiotic synthetase, putative 0.0032 0.001 0.0199
Echinococcus granulosus sodium:glucose cotransporter 0.004 0.0026 0.0034
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0303 0.049 0.125
Mycobacterium ulcerans hypothetical protein 0.0107 0.0144 0.0957
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0032 0.001 0.0026
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0032 0.001 0.0132
Loa Loa (eye worm) hypothetical protein 0.0738 0.1258 0.3339
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0148 0.0217 0.0297
Echinococcus granulosus glycine receptor subunit beta 0.0202 0.0311 0.0428
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0145 0.021 0.1303
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0078 0.0093 0.0233
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0032 0.001 0.0026
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0202 0.0311 0.0428
Brugia malayi FXNA 0.0148 0.0217 0.0571
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0202 0.0311 0.0428
Brugia malayi neuropeptide F receptor 0.0145 0.021 0.0555
Loa Loa (eye worm) Ulp1 protease 0.0027 0.0002 0.0001
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0072 0.0082 0.056
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0107 0.0144 0.0957
Echinococcus granulosus inositol monophosphatase 1 0.0029 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0011
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0032 0.001 0.0035
Schistosoma mansoni tyrosine kinase 0.0164 0.0245 0.0243
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.001 0.0035
Echinococcus multilocularis sodium:glucose cotransporter 2 0.004 0.0026 0.0034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1063 0.183 0.2529
Echinococcus granulosus 7TM GPCR rhodopsin 0.0145 0.021 0.0289
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0104 0.0137 0.0136
Schistosoma mansoni DNA polymerase eta 0.0105 0.0141 0.0139
Trichomonas vaginalis esterase, putative 0.0148 0.0216 0.5164
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0023 0.0496
Echinococcus granulosus mitogen activated protein kinase 3 0.0113 0.0154 0.0211
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Loa Loa (eye worm) hypothetical protein 0.0105 0.0141 0.037
Onchocerca volvulus Neuropeptide F receptor homolog 0.0145 0.021 0.1303
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0075 0.0074
Brugia malayi LBP/BPI 0.025 0.0396 0.1047
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0113 0.0154 0.0635
Echinococcus granulosus expressed conserved protein 0.0281 0.045 0.062
Onchocerca volvulus 0.0032 0.001 0.0052
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0032 0.001 0.0021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0128 0.0126
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0083 0.0207
Echinococcus multilocularis Biotin lipoyl attachment 0.0078 0.0093 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Leishmania major acetyl-CoA synthetase, putative 0.0032 0.001 0.0021
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0303 0.049 0.3333
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0308 0.0498 0.0496
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.004 0.0025 0.0082
Echinococcus multilocularis sentrin specific protease 7 0.0308 0.0498 0.0686
Loa Loa (eye worm) hypothetical protein 0.0035 0.0016 0.0037
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0032 0.001 0.0021
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0667 0.1133 0.4718
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0303 0.049 0.0675
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0035 0.0016 0.0019
Schistosoma mansoni caspase-7 (C14 family) 0.0029 0.0006 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0145 0.021 0.0209
Plasmodium vivax glutathione reductase, putative 0.0033 0.0014 0.0042
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0078 0.0093 0.0091
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0076 0.0089 0.0225
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0104 0.0137 0.0361
Brugia malayi nuclear receptor NHR-88 0.0035 0.0016 0.0037
Echinococcus multilocularis serotonin receptor 0.0145 0.021 0.0289
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0145 0.021 0.0555
Echinococcus granulosus biogenic amine 5HT receptor 0.0145 0.021 0.0289
Brugia malayi RNA recognition motif domain containing protein 0.0071 0.008 0.0208
Schistosoma mansoni survival motor neuron protein 0.0081 0.0097 0.0096
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0157 0.0645
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0016 0.0037
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.001 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.0145 0.021 0.0289
Brugia malayi beta-lactamase family protein 0.0148 0.0216 0.057
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0852 0.1459 0.1457
Mycobacterium tuberculosis Probable oxidoreductase 0.0085 0.0105 0.0265
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0145 0.021 0.0289
Treponema pallidum pyruvate carboxylase subunit B 0.0078 0.0093 0.1764
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0035 0.0016 0.0037
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0133 0.0547
Trypanosoma brucei protein kinase, putative 0.0113 0.0154 0.039
Loa Loa (eye worm) hypothetical protein 0.064 0.1084 0.2878
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0005 0.0013
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0098 0.0128 0.0175
Schistosoma mansoni Replicative DNA helicase 0.0257 0.0409 0.0408
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0032 0.001 0.0012
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0027 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0081 0.0099 0.0097
Schistosoma mansoni inositol transporter 0.004 0.0026 0.0025
Trypanosoma brucei hypothetical protein, conserved 0.0148 0.0216 0.0549
Echinococcus multilocularis orexin receptor type 2 0.0145 0.021 0.0289
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0202 0.0311 0.0428
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0085 0.0105 0.0717
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0006 0.0088
Echinococcus multilocularis epidermal growth factor receptor 0.0088 0.011 0.0151
Schistosoma mansoni hypothetical protein 0.0081 0.0099 0.0097
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0145 0.021 0.0555
Brugia malayi acetyltransferase, GNAT family protein 0.016 0.0236 0.0624
Echinococcus granulosus neuropeptide Y receptor 0.0145 0.021 0.0289
Echinococcus multilocularis sentrin specific protease 8 0.0027 0.0002 0.0001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0083 0.0338
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0116 0.0159 0.0403
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0145 0.021 0.0209
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0303 0.049 0.3333
Brugia malayi nuclear hormone receptor 0.0035 0.0016 0.0037
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0011 0.0012
Plasmodium falciparum metacaspase 1 0.0029 0.0006 0.0013
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0029 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0336 0.0547 0.145
Brugia malayi GnHR receptor homolog 0.0145 0.021 0.0555
Echinococcus multilocularis mitogen activated protein kinase 14 0.014 0.0202 0.0277
Trypanosoma cruzi metacaspase, putative 0.0029 0.0006 0.0015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0035 0.0016 0.0084
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0006 0.0088
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0852 0.1458 0.3734
Onchocerca volvulus 0.0336 0.0547 0.3411
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0098 0.0128 0.0175
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0381 0.0628 1
Leishmania major dihydrolipoamide acetyltransferase precursor, putative 0.0078 0.0093 0.0233
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0006 0.0088
Loa Loa (eye worm) hypothetical protein 0.008 0.0096 0.0252
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Echinococcus multilocularis thyroid hormone receptor alpha 0.0116 0.016 0.0219
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0145 0.021 0.0555
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0029 0.0038
Chlamydia trachomatis recombinase RecA 0.0072 0.0082 0.0603
Giardia lamblia DINP protein human, muc B family 0.0077 0.009 0.1411
Schistosoma mansoni hypothetical protein 0.0145 0.021 0.0209
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0016 0.0019
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0038 0.0126
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0035 0.0016 0.0014
Plasmodium falciparum lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 0.0078 0.0093 0.0323
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Onchocerca volvulus 0.0104 0.0137 0.0847
Giardia lamblia Kinase, PLK 0.0101 0.0133 0.2097
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0145 0.021 0.0555
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0085 0.0105 0.0265
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0128 0.0126
Echinococcus granulosus neuropeptide Y receptor 0.0145 0.021 0.0289
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0303 0.049 0.2034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0035 0.0016 0.0037
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.001 0.0071
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0303 0.049 0.3333
Brugia malayi Melatonin receptor type 1A 0.0145 0.021 0.0555
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0202 0.0311 0.0309
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0006 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0133 0.3167
Brugia malayi G-protein coupled receptor 0.0145 0.021 0.0555
Mycobacterium tuberculosis Biotinylated protein TB7.3 0.0078 0.0093 0.0236
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0852 0.1458 0.2014
Trypanosoma cruzi hypothetical protein, conserved 0.0148 0.0216 0.0893
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0202 0.0311 0.0309
Echinococcus granulosus sodium:myo inositol cotransporter 0.004 0.0026 0.0034
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0123 0.0172 0.0236
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0202 0.0311 0.0822
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0078 0.0093 0.0091
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0202 0.0311 0.0428
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0101 0.0133 0.0182
Schistosoma mansoni neurotransmitter gated ion channel 0.0098 0.0128 0.0126
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0078 0.0093 0.0638
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.004 0.0025 0.0082
Onchocerca volvulus 0.0145 0.021 0.1303
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0154 0.3673
Schistosoma mansoni amine GPCR 0.0145 0.021 0.0209
Schistosoma mansoni sodium/solute symporter 0.004 0.0026 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0145 0.021 0.0289
Onchocerca volvulus 0.0145 0.021 0.1303
Toxoplasma gondii thioredoxin reductase 0.0033 0.0014 0.003
Echinococcus multilocularis neuropeptides capa receptor 0.0145 0.021 0.0289
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0016 0.0037
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0078 0.0093 0.0233
Echinococcus granulosus survival motor neuron protein 1 0.0396 0.0654 0.0902
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0032 0.001 0.0023
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0027 0.0002 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0145 0.021 0.0289
Echinococcus granulosus muscleblind protein 0.0294 0.0473 0.0652
Brugia malayi excitatory GABA receptor EXP-1A 0.0202 0.0311 0.0822
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0087 0.0356
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0075 0.0087 0.0119
Onchocerca volvulus 0.0098 0.0128 0.0788
Loa Loa (eye worm) hypothetical protein 0.0104 0.0137 0.0361
Loa Loa (eye worm) G-protein coupled receptor 0.0145 0.021 0.0555
Mycobacterium tuberculosis Probable lipase LipD 0.0148 0.0216 0.0548
Trypanosoma brucei metacaspase 5, putative 0.0029 0.0006 0.0009
Echinococcus multilocularis caspase 2 0.0029 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0087 0.0356
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0016 0.0037
Schistosoma mansoni tar DNA-binding protein 0.0071 0.008 0.0078
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0031 0.0102
Trypanosoma brucei metacaspase MCA2 0.0029 0.0006 0.0009
Leishmania major DNA polymerase eta, putative 0.0105 0.0141 0.0355
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0035 0.0016 0.0037
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Echinococcus multilocularis ecdysone induced protein 78C 0.0035 0.0016 0.0019
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0133 0.0547
Loa Loa (eye worm) hypothetical protein 0.0085 0.0104 0.0272
Echinococcus granulosus neuropeptide receptor 0.0145 0.021 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0145 0.021 0.0289
Brugia malayi hypothetical protein 0.0098 0.0128 0.0336
Loa Loa (eye worm) hypothetical protein 0.0148 0.0216 0.057
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0145 0.021 0.0289
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0116 0.0159 0.1061
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0303 0.049 0.3358
Leishmania major hypothetical protein, conserved 0.0148 0.0217 0.055
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.0193 0.0295 0.075
Leishmania major basic transcription factor 3a, putative 0.0039 0.0023 0.0053
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0148 0.0216 0.0548
Loa Loa (eye worm) ICD-1 protein 0.0039 0.0023 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0048 0.0118
Echinococcus granulosus neuropeptide s receptor 0.0651 0.1105 0.1525
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0852 0.1458 0.6076
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0148 0.0216 0.057
Plasmodium vivax thioredoxin reductase, putative 0.0033 0.0014 0.0042
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0145 0.021 0.0289
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.016 0.0236 0.0235
Trypanosoma brucei polo-like protein kinase 0.0101 0.0133 0.0336
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0303 0.049 0.125
Mycobacterium ulcerans recombinase A 0.0072 0.0082 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0006 0.0088
Brugia malayi Tachykinin-like peptides receptor 99D 0.0145 0.021 0.0555
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Echinococcus multilocularis protein patched 0.0085 0.0104 0.0142
Brugia malayi MH2 domain containing protein 0.039 0.0643 0.1704
Trypanosoma brucei membrane transporter protein, putative 0.0075 0.0087 0.0219
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0202 0.0311 0.0309
Loa Loa (eye worm) hypothetical protein 0.0078 0.0093 0.0243
Schistosoma mansoni steroid hormone receptor ad4bp 0.0035 0.0016 0.0014
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.334 0.5849 0.8086
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0087 0.0356
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0078 0.0093 0.0091
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0052 0.0047 0.0116
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.1023
Brugia malayi Pre-SET motif family protein 0.0034 0.0014 0.0033
Loa Loa (eye worm) beta-lactamase 0.0148 0.0216 0.057
Echinococcus multilocularis microtubule associated protein 2 0.314 0.5497 0.76
Loa Loa (eye worm) acetyltransferase 0.016 0.0236 0.0624
Trypanosoma brucei acetyl-CoA carboxylase 0.2236 0.3902 1
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Onchocerca volvulus 0.0585 0.0988 0.617
Schistosoma mansoni hypothetical protein 0.0374 0.0616 0.0614
Entamoeba histolytica hypothetical protein 0.0191 0.0292 0.464
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0006 0.0013
Brugia malayi sulfakinin receptor protein 0.0145 0.021 0.0555
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0001
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0029 0.0005 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0145 0.021 0.0209
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0076 0.0089 0.0225
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0077 0.009 0.0123
Echinococcus granulosus mitogen activated protein kinase 0.0113 0.0154 0.0211
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0148 0.0216 0.0548
Loa Loa (eye worm) hypothetical protein 0.0148 0.0217 0.0571
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0032 0.001 0.0012
Mycobacterium tuberculosis Conserved protein 0.0148 0.0216 0.0548
Onchocerca volvulus 0.0585 0.0988 0.617
Loa Loa (eye worm) leucyl aminopeptidase 0.0148 0.0217 0.0571
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0029 0.0006 0.0004
Echinococcus multilocularis neuropeptide receptor 0.0145 0.021 0.0289
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0336 0.0547 0.145
Echinococcus granulosus mitogen activated protein kinase 11 0.014 0.0202 0.0277
Schistosoma mansoni tyrosine kinase 0.0088 0.011 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Onchocerca volvulus 0.0145 0.021 0.1303
Brugia malayi AKH receptor 0.0145 0.021 0.0555
Onchocerca volvulus 0.0145 0.021 0.1303
Loa Loa (eye worm) oxidoreductase 0.0032 0.001 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0202 0.0311 0.0428
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0116 0.0159 0.0403
Mycobacterium tuberculosis Conserved hypothetical protein 0.0352 0.0575 0.146
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni microtubule-associated protein tau 0.314 0.5497 0.5496
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.0023 0.0073
Echinococcus granulosus sentrin specific protease 1 0.0027 0.0002 0.0001
Trypanosoma cruzi metacaspase 5, putative 0.0029 0.0006 0.0015
Schistosoma mansoni tyrosine kinase 0.0087 0.0109 0.0107
Onchocerca volvulus 0.0035 0.0016 0.0084
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0032 0.001 0.0071
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0128 0.0175
Onchocerca volvulus 0.004 0.0026 0.015
Echinococcus multilocularis serotonin receptor 0.0145 0.021 0.0289
Entamoeba histolytica acyl-CoA synthetase, putative 0.0107 0.0144 0.2272
Loa Loa (eye worm) hypothetical protein 0.0078 0.0093 0.0243
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0202 0.0311 0.0428
Echinococcus multilocularis fmrfamide receptor 0.0145 0.021 0.0289
Leishmania major hypothetical protein, conserved 0.0075 0.0087 0.0219
Onchocerca volvulus 0.0202 0.0311 0.1931
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0083 0.0113
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0107 0.0144 0.0366
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Loa Loa (eye worm) GABA receptor subunit 0.0104 0.0137 0.0361
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0003 0.0007
Brugia malayi glutathione reductase 0.0033 0.0014 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0107 0.0144 0.0957
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0098 0.0128 0.0336
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0202 0.0311 0.0428
Echinococcus granulosus caspase 3 0.0079 0.0095 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0145 0.021 0.0289
Echinococcus granulosus g protein coupled receptor 0.0145 0.021 0.0289
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.014 0.0202 0.0833
Echinococcus granulosus neuropeptide receptor 0.0145 0.021 0.0289
Echinococcus multilocularis mitogen activated protein kinase 0.0113 0.0154 0.0211
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0035 0.0016 0.0019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0128 0.0336
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0098 0.0128 0.0336
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Loa Loa (eye worm) TYRA-2 protein 0.0145 0.021 0.0555
Schistosoma mansoni neurotransmitter gated ion channel 0.0098 0.0128 0.0126
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0148 0.0217 0.0215
Loa Loa (eye worm) TAR-binding protein 0.0071 0.008 0.0208
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0006 0.0088
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0852 0.1458 0.6076
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0087 0.0356
Treponema pallidum recombinase A 0.0072 0.0082 0.1468
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0048 0.0118
Brugia malayi AMP-binding enzyme family protein 0.0107 0.0144 0.0379
Echinococcus multilocularis muscleblind protein 1 0.0294 0.0473 0.0652
Echinococcus multilocularis epidermal growth factor receptor 0.0164 0.0245 0.0336
Mycobacterium tuberculosis Probable branched-chain keto acid dehydrogenase E2 component BkdC 0.0078 0.0093 0.0236
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Trypanosoma cruzi glutaminyl cyclase, putative 0.0148 0.0217 0.0895
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0303 0.049 0.3358
Trypanosoma brucei trypanothione reductase 0.0033 0.0014 0.003
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0032 0.001 0.0026
Onchocerca volvulus 0.0145 0.021 0.1303
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.009 0.0226
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0078 0.0093 0.0243
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.2236 0.3902 0.5394
Onchocerca volvulus 0.0145 0.021 0.1303
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0946 0.1624 0.4122
Onchocerca volvulus 0.0145 0.021 0.1303
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.008 0.0096 0.0715
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0133 0.0132
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0023 0.0086
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0027 0.0002 0.0001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0032 0.001 0.0035
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0303 0.049 0.0675
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0128 0.0126
Toxoplasma gondii peptidase, M28 family protein 0.0148 0.0217 0.055
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0145 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0122 0.017 0.0449
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Echinococcus granulosus microsomal glutathione S transferase 3 0.0123 0.0172 0.0236
Schistosoma mansoni amine GPCR 0.0145 0.021 0.0209
Echinococcus multilocularis dna polymerase kappa 0.0077 0.009 0.0123
Loa Loa (eye worm) hypothetical protein 0.0035 0.0016 0.0037
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0088 0.011 0.0151
Trypanosoma cruzi DNA polymerase eta, putative 0.0105 0.0141 0.0578
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0202 0.0311 0.0822
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0107 0.0144 0.0957
Echinococcus multilocularis g protein coupled receptor 0.0145 0.021 0.0289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0035 0.0016 0.0037
Loa Loa (eye worm) hypothetical protein 0.0104 0.0137 0.0361
Schistosoma mansoni retinoic acid receptor RXR 0.0035 0.0016 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0006 0.0088
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0107 0.0144 0.0366
Echinococcus multilocularis G-protein coupled receptor, putative 0.0145 0.021 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.025 0.0396 0.95
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0104 0.0142
Schistosoma mansoni hypothetical protein 0.0145 0.021 0.0209
Onchocerca volvulus 0.0202 0.0311 0.1931
Loa Loa (eye worm) hypothetical protein 0.0148 0.0217 0.0571
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0104 0.0142
Brugia malayi photoreceptor-specific nuclear receptor 0.0035 0.0016 0.0037
Entamoeba histolytica serine/threonine protein kinase, putative 0.0101 0.0133 0.2097
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0078 0.0093 0.0126
Mycobacterium tuberculosis Probable esterase LipL 0.0148 0.0216 0.0548
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0217 0.5176
Echinococcus granulosus alpha 1A adrenergic receptor 0.0145 0.021 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0023 0.0496
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.014 0.0202 0.0512
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.001 0.0035
Echinococcus granulosus sodium:glucose cotransporter 2 0.004 0.0026 0.0034
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0032 0.001 0.0021
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0069 0.0076 0.0103
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0038 0.0091
Mycobacterium ulcerans acetyl-CoA synthetase 0.0032 0.001 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0133 0.3167
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0052 0.0047 0.0063
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0006 0.0088
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0145 0.021 0.0209
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0072 0.0082 0.0525
Echinococcus granulosus thioredoxin glutathione reductase 0.0033 0.0014 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0032 0.001 0.0023
Echinococcus multilocularis glycine receptor subunit beta 0.0202 0.0311 0.0428
Onchocerca volvulus Serine\/threonine kinase homolog 0.0101 0.0133 0.0821
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0202 0.0311 0.0428
Plasmodium falciparum dihydrolipoamide acyltransferase component E2 0.0078 0.0093 0.0323
Loa Loa (eye worm) hypothetical protein 0.025 0.0396 0.1047
Toxoplasma gondii hypothetical protein 0.0108 0.0145 0.0366
Echinococcus granulosus g protein coupled receptor 0.0145 0.021 0.0289
Brugia malayi ImpB/MucB/SamB family protein 0.0105 0.0141 0.037
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0133 0.3167
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0145 0.021 0.0289
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0077 0.009 0.0226
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0078 0.0093 0.0126
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0303 0.049 0.2034
Loa Loa (eye worm) hypothetical protein 0.0148 0.0216 0.057
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0023 0.0086
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0031 0.0456
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0852 0.1458 1
Toxoplasma gondii dihydrolipoamide acyltransferase, putative 0.0078 0.0093 0.0233
Echinococcus multilocularis g protein coupled receptor 0.0145 0.021 0.0289
Schistosoma mansoni nAChR subunit 0.0202 0.0311 0.0309
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0193 0.0295 0.1991
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0148 0.0216 0.1451
Echinococcus granulosus rhodopsin orphan GPCR 0.0145 0.021 0.0289
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0014 0.0012
Onchocerca volvulus 0.0202 0.0311 0.1931
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Leishmania major trypanothione reductase 0.0033 0.0014 0.003
Echinococcus multilocularis expressed conserved protein 0.0281 0.045 0.062
Loa Loa (eye worm) hypothetical protein 0.0294 0.0473 0.1254
Mycobacterium tuberculosis Probable reductase 0.0076 0.009 0.0227
Loa Loa (eye worm) hypothetical protein 0.008 0.0096 0.0252
Echinococcus multilocularis neuropeptide receptor 0.0145 0.021 0.0289
Echinococcus granulosus tm gpcr rhodopsin 0.0145 0.021 0.0289
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0145 0.021 0.0555
Schistosoma mansoni patched 1 0.0085 0.0104 0.0102
Echinococcus multilocularis conserved hypothetical protein 0.076 0.1296 0.179
Echinococcus granulosus peptide allatostatin:somatostatin 0.0145 0.021 0.0289
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0027 0.0002 0.0001
Schistosoma mansoni neuropeptide receptor 0.0145 0.021 0.0209
Brugia malayi ORL1-like opioid receptor 0.0145 0.021 0.0555
Schistosoma mansoni hypothetical protein 0.0034 0.0015 0.0013
Echinococcus multilocularis caspase 0.0108 0.0146 0.0199
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0303 0.049 0.3333
Leishmania major DNA polymerase eta, putative 0.0052 0.0047 0.0116
Loa Loa (eye worm) thioredoxin reductase 0.0033 0.0014 0.0032
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0098 0.0128 0.0336
Loa Loa (eye worm) hypothetical protein 0.0367 0.0602 0.1596
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0202 0.0311 0.0428
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0035 0.0016 0.0037
Trypanosoma cruzi dihydrolipoamide acetyltransferase, putative 0.0078 0.0093 0.0379
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0145 0.021 0.0209
Schistosoma mansoni amine GPCR 0.0145 0.021 0.0209
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0202 0.0311 0.0428
Entamoeba histolytica deoxycytidyl transferase, putative 0.0077 0.009 0.1411
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0852 0.1458 0.3701
Onchocerca volvulus Glutaminyl cyclase homolog 0.0932 0.16 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0077 0.009 0.0089
Brugia malayi AMP-binding enzyme family protein 0.0032 0.001 0.0023
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0308 0.0498 0.7918
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0108 0.0146 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0104 0.2458
Schistosoma mansoni growth hormone secretagogue receptor 0.0145 0.021 0.0209
Echinococcus multilocularis nAChR subunit 0.0104 0.0137 0.0188
Brugia malayi Serotonin receptor 0.0651 0.1105 0.2932
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0303 0.049 0.2034
Echinococcus granulosus beta LACTamase domain containing family member 0.0148 0.0216 0.0297
Echinococcus granulosus somatostatin receptor 0.0145 0.021 0.0289
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Echinococcus granulosus mitogen activated protein kinase 14 0.014 0.0202 0.0277
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0193 0.0295 0.1041
Trypanosoma cruzi membrane transporter protein, putative 0.0075 0.0087 0.0356
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0202 0.0311 0.0822
Brugia malayi Peptidase family M28 containing protein 0.0932 0.16 0.4249
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0202 0.0311 0.0822
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0116 0.0159 0.0218
Brugia malayi Muscleblind-like protein 0.0294 0.0473 0.1254
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0006 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0035 0.0016 0.0037
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0145 0.021 0.0289
Trypanosoma brucei unspecified product 0.0053 0.0048 0.0118
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0145 0.021 0.0289
Echinococcus granulosus Niemann Pick C1 protein 0.0282 0.0452 0.0622
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0202 0.0311 0.0822
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0852 0.1458 0.3701
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0076 0.0089 0.0225
Mycobacterium ulcerans acyl-CoA synthetase 0.0107 0.0144 0.0957
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0001
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0145 0.021 0.0289
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0016 0.0037
Schistosoma mansoni neuropeptide receptor 0.0145 0.021 0.0209
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0014 0.0017
Brugia malayi putative neuropeptide receptor 0.0145 0.021 0.0555
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0128 0.0175
Trypanosoma brucei metacaspase 0.0029 0.0006 0.0009
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0078 0.0093 0.0379
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0078 0.0093 0.0126
Loa Loa (eye worm) hypothetical protein 0.0122 0.017 0.0449
Mycobacterium ulcerans pyruvate carboxylase 0.0852 0.1458 1
Mycobacterium ulcerans esterase/lipase LipP 0.0148 0.0216 0.1451
Echinococcus multilocularis rhodopsin orphan GPCR 0.0145 0.021 0.0289
Mycobacterium ulcerans hypothetical protein 0.0148 0.0216 0.1451
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0006 0.0088
Leishmania major 4-coumarate:coa ligase-like protein 0.0107 0.0144 0.0365
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus granulosus Biotin lipoyl attachment 0.0078 0.0093 0.0126
Echinococcus multilocularis sex peptide receptor 0.0145 0.021 0.0289
Echinococcus multilocularis sodium:myo inositol cotransporter 0.004 0.0026 0.0034
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1618 0.2811 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0083 0.0338
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.009 0.0236
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0257 0.0409 0.278
Schistosoma mansoni alpha-1 adrenergic receptor 0.0145 0.021 0.0209
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0014 0.0049
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.0308 0.0306
Onchocerca volvulus 0.0145 0.021 0.1303
Echinococcus granulosus hypothetical protein 0.0905 0.1552 0.2144
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0082 0.0099 0.0135
Onchocerca volvulus 0.0098 0.0128 0.0788
Echinococcus multilocularis caspase 3 0.0079 0.0095 0.0129
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0145 0.021 0.0289
Echinococcus multilocularis sodium channel protein 0.0337 0.0549 0.0758
Loa Loa (eye worm) hypothetical protein 0.0601 0.1015 0.2694
Loa Loa (eye worm) hypothetical protein 0.0585 0.0988 0.2622
Leishmania major DNA polymerase kappa, putative 0.0077 0.009 0.0226
Schistosoma mansoni opsin-like receptor 0.0145 0.021 0.0209
Onchocerca volvulus 0.0032 0.0011 0.0053
Echinococcus granulosus allatostatin A receptor 0.0145 0.021 0.0289
Echinococcus multilocularis solute carrier family 5 0.004 0.0026 0.0034
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Onchocerca volvulus 0.0081 0.0097 0.0596
Brugia malayi Thioredoxin reductase 0.0033 0.0014 0.0032
Onchocerca volvulus 0.0148 0.0217 0.1342
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0113 0.0154 0.0635
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni biogenic amine (5HT) receptor 0.0145 0.021 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Echinococcus multilocularis glycine receptor subunit beta 0.0202 0.0311 0.0428
Giardia lamblia Kinase, CMGC MAPK 0.0113 0.0154 0.2431
Plasmodium falciparum metacaspase-like protein 0.0029 0.0006 0.0013
Toxoplasma gondii ABC1 family protein 0.0148 0.0216 0.0549
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0585 0.0988 0.2622
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0078 0.0093 0.0236
Trichomonas vaginalis penicillin-binding protein, putative 0.0148 0.0216 0.5164
Loa Loa (eye worm) hypothetical protein 0.0035 0.0016 0.0037
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Onchocerca volvulus 0.0202 0.0311 0.1931
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0145 0.021 0.0289
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0116 0.0159 0.1194
Schistosoma mansoni glutaminyl cyclase (M28 family) 0.0932 0.16 0.1599
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0035 0.0016 0.0019
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0035 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0032
Onchocerca volvulus 0.0148 0.0216 0.1339
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0078 0.0093 0.0604
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0077 0.009 0.0236
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0113 0.0154 0.0635
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0585 0.0988 0.2622
Chlamydia trachomatis replicative DNA helicase 0.0257 0.0409 0.3089
Echinococcus multilocularis peptidase Clp (S14 family) 0.0076 0.0089 0.0121
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0029 0.0005 0.005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0029 0.0005 0.0076
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus granulosus tumor protein p63 0.0228 0.0358 0.0493
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.0023 0.0073
Onchocerca volvulus 0.0202 0.0311 0.1931
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0076 0.0089 0.061
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0032 0.001 0.0023
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0035 0.0016 0.0014
Schistosoma mansoni nAChR subunit 0.0202 0.0311 0.0309
Echinococcus multilocularis caspase 8 0.0029 0.0006 0.0006
Plasmodium falciparum carbamoyl phosphate synthetase 0.0193 0.0295 0.1041
Echinococcus multilocularis survival motor neuron protein 1 0.0396 0.0654 0.0902
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0303 0.049 0.3333
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Loa Loa (eye worm) transcription factor SMAD2 0.039 0.0643 0.1704
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0001
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0852 0.1458 0.2014
Brugia malayi nicalin 0.0148 0.0217 0.0571
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0032 0.001 0.0026
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0113 0.0154 0.039
Leishmania major dihydrolipoamide branched chain transacylase, putative 0.0078 0.0093 0.0233
Mycobacterium leprae Conserved hypothetical protein 0.0759 0.1295 0.8878
Brugia malayi Furin-like cysteine rich region family protein 0.0164 0.0245 0.0646
Echinococcus granulosus sodium channel protein 0.0337 0.0549 0.0758
Brugia malayi Dopamine receptor protein 1 0.0145 0.021 0.0555
Echinococcus multilocularis neuropeptide Y receptor 0.0145 0.021 0.0289
Loa Loa (eye worm) LGC-31 protein 0.0202 0.0311 0.0822
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.001 0.0035
Trypanosoma brucei metacaspase MCA3 0.0029 0.0006 0.0009
Echinococcus granulosus transcription factor btf3 0.0039 0.0023 0.0029
Schistosoma mansoni biogenic amine receptor 0.0145 0.021 0.0209
Onchocerca volvulus Fxna peptidase homolog 0.0148 0.0217 0.1342
Onchocerca volvulus 0.0098 0.0128 0.0788
Leishmania major metacaspase, putative 0.0029 0.0006 0.0009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0191 0.0292 0.0402
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.014 0.0202 0.0532
Mycobacterium ulcerans hypothetical protein 0.0148 0.0217 0.1454
Trypanosoma cruzi metacaspase, putative 0.0029 0.0006 0.0015
Echinococcus granulosus tachykinin peptides receptor 99D 0.0145 0.021 0.0289
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0016 0.0019
Echinococcus granulosus neuropeptides capa receptor 0.0145 0.021 0.0289
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0104 0.0137 0.0361
Mycobacterium tuberculosis Conserved protein 0.0148 0.0217 0.055
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0585 0.0988 0.2622
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0852 0.1458 1
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Onchocerca volvulus 0.0585 0.0988 0.617
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0133 0.3167
Loa Loa (eye worm) inositol-1 0.0029 0.0005 0.001
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0101 0.0133 0.0182
Trichomonas vaginalis D-aminoacylase, putative 0.0148 0.0216 0.5164
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0148 0.0216 0.0548
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0006 0.0088
Echinococcus multilocularis neuropeptide receptor A26 0.0651 0.1105 0.1525
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0032 0.001 0.0026
Onchocerca volvulus 0.0585 0.0988 0.617
Brugia malayi GH02984p 0.0367 0.0602 0.1596
Echinococcus granulosus rhodopsin orphan GPCR 0.0145 0.021 0.0289
Echinococcus granulosus G protein coupled receptor 139 0.0145 0.021 0.0289
Brugia malayi steroid hormone receptor 0.0035 0.0016 0.0037
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0027 0.0002 0.0001
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0083 0.0216
Echinococcus multilocularis high affinity choline transporter 1 0.0367 0.0602 0.083
Schistosoma mansoni tyrosine kinase 0.0087 0.0109 0.0107
Echinococcus granulosus solute carrier family 5 0.004 0.0026 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0145 0.021 0.0209
Echinococcus granulosus fmrfamide receptor 0.0145 0.021 0.0289
Echinococcus multilocularis thioredoxin glutathione reductase 0.0033 0.0014 0.0017
Trypanosoma cruzi glutaminyl cyclase, putative 0.0148 0.0217 0.0895
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0667 0.1133 0.4718
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0076 0.009 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0006 0.0088
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0035 0.0016 0.0019
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0303 0.049 0.0488
Schistosoma mansoni tar DNA-binding protein 0.0071 0.008 0.0078
Schistosoma mansoni acetylcholine receptor-related 0.0098 0.0128 0.0126
Loa Loa (eye worm) hypothetical protein 0.0116 0.0159 0.042
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0154 0.3673
Echinococcus multilocularis somatostatin receptor 0.0145 0.021 0.0289
Onchocerca volvulus 0.0145 0.021 0.1303
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0035 0.0016 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0145 0.021 0.0289
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0076 0.0089 0.0226
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0006 0.0009
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0085 0.0105 0.0265
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0303 0.049 0.1243
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0116 0.0159 0.056
Schistosoma mansoni nAChR subunit 0.0202 0.0311 0.0309
Schistosoma mansoni thyroid hormone receptor 0.0116 0.016 0.0158
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0005 0.0008
Leishmania major hypothetical protein, conserved 0.0148 0.0216 0.0549
Loa Loa (eye worm) hypothetical protein 0.008 0.0096 0.0252
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0191 0.0292 0.0402
Brugia malayi ecdysteroid receptor 0.0035 0.0016 0.0037
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0145 0.021 0.0289
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0148 0.0216 0.0214
Loa Loa (eye worm) hypothetical protein 0.0336 0.0547 0.145
Onchocerca volvulus 0.0145 0.021 0.1303
Brugia malayi hypothetical protein 0.0336 0.0547 0.145
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0852 0.1459 0.1457
Brugia malayi G protein-coupled receptor F59B2.13 0.0145 0.021 0.0555
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0006 0.0088
Brugia malayi Protein kinase domain containing protein 0.0052 0.0047 0.0122
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0738 0.1258 0.3339
Echinococcus granulosus serotonin receptor 0.0145 0.021 0.0289
Schistosoma mansoni nAChR subunit 0.0202 0.0311 0.0309
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0585 0.0988 0.2622
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.0302 0.0416
Schistosoma mansoni hypothetical protein 0.0374 0.0616 0.0614
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0027 0.0002 0.0001
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0202 0.0311 0.0822
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0133 0.3167
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni multidrug resistance protein 0.0075 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0104 0.0137 0.0361
Schistosoma mansoni neurotransmitter gated ion channel 0.0104 0.0137 0.0136
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0035 0.0016 0.0037
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0032 0.001 0.0026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0202 0.0311 0.0822
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0145 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.008 0.0096 0.0252
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Onchocerca volvulus 0.0035 0.0017 0.0091
Trypanosoma cruzi DNA polymerase eta, putative 0.0052 0.0047 0.0188
Loa Loa (eye worm) hypothetical protein 0.0029 0.0006 0.0011
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0202 0.0311 0.0822
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0083 0.1293
Schistosoma mansoni histamine h1 receptor 0.0145 0.021 0.0209
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0145 0.021 0.0209
Echinococcus multilocularis rhodopsin orphan GPCR 0.0145 0.021 0.0289
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0202 0.0311 0.0428
Onchocerca volvulus Huntingtin homolog 0.0122 0.017 0.1053
Schistosoma mansoni nAChR subunit 0.0098 0.0128 0.0126
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0104 0.0142
Entamoeba histolytica acyl-CoA synthetase, putative 0.0107 0.0144 0.2272
Brugia malayi beta-lactamase family protein 0.0148 0.0216 0.057
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0667 0.1133 0.2899
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0303 0.049 0.125
Entamoeba histolytica hypothetical protein 0.0104 0.0137 0.2163
Toxoplasma gondii carbamoylphosphate synthetase 0.0193 0.0295 0.075
Schistosoma mansoni inositol transporter 0.004 0.0026 0.0025
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0257 0.0409 0.2806
Brugia malayi Sodium:solute symporter family protein 0.004 0.0026 0.0065
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.0193 0.0295 0.122
Brugia malayi Serotonin receptor 0.0145 0.021 0.0555
Onchocerca volvulus 0.0336 0.0547 0.3411
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0048 0.0118
Echinococcus multilocularis transcription factor btf3 0.0039 0.0023 0.0029
Loa Loa (eye worm) glutathione reductase 0.0033 0.0014 0.0032
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0193 0.0295 0.1991
Echinococcus multilocularis g protein coupled receptor 0.0145 0.021 0.0289
Brugia malayi AMP-binding enzyme family protein 0.0032 0.001 0.0023
Echinococcus granulosus g protein coupled receptor 0.0145 0.021 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0133 0.3167
Onchocerca volvulus 0.0145 0.021 0.1303
Loa Loa (eye worm) hypothetical protein 0.0035 0.0016 0.0037
Schistosoma mansoni neuropeptide receptor 0.0145 0.021 0.0209
Leishmania major acetyl-CoA carboxylase, putative 0.2236 0.3902 1
Echinococcus multilocularis 0.0051 0.0044 0.0059
Loa Loa (eye worm) hypothetical protein 0.0932 0.16 0.4249
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0202 0.0311 0.0428
Schistosoma mansoni cpg binding protein 0.0032 0.0011 0.0009
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0145 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0145 0.021 0.0289
Brugia malayi Steroid receptor seven-up type 2 0.0035 0.0016 0.0037
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.001 0.0035
Brugia malayi hypothetical protein 0.0098 0.0128 0.0336
Echinococcus multilocularis dro:myosuppressin receptor 0.0145 0.021 0.0289
Schistosoma mansoni tyrosine kinase 0.0052 0.0047 0.0046
Schistosoma mansoni thyroid hormone receptor 0.0116 0.016 0.0158
Brugia malayi P38 map kinase family protein 2 0.014 0.0202 0.0532
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0032 0.001 0.0034
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0071 0.008 0.0208
Entamoeba histolytica hypothetical protein 0.0039 0.0023 0.0328
Brugia malayi CHE-14 protein 0.0085 0.0104 0.0272
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0076 0.009 0.0227
Brugia malayi Probable ClpP-like protease 0.0116 0.0159 0.042
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0078 0.0093 0.0233
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0303 0.049 0.3358
Mycobacterium ulcerans lipase LipD 0.0148 0.0216 0.1451
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0145 0.021 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Brugia malayi G protein-coupled receptor 0.0145 0.021 0.0555
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0303 0.049 0.1243
Toxoplasma gondii NAC domain-containing protein 0.0039 0.0023 0.0053
Chlamydia trachomatis biotin carboxylase 0.0773 0.132 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0145 0.021 0.0555
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.1023
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0145 0.021 0.0289
Toxoplasma gondii hypothetical protein 0.004 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0148 0.0217 0.0571
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0107 0.0144 0.099
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0202 0.0311 0.0822
Mycobacterium ulcerans lipoprotein aminopeptidase LpqL 0.0148 0.0217 0.1454
Brugia malayi hypothetical protein 0.0122 0.017 0.0449
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0145 0.021 0.0289
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.0193 0.0295 0.122
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0098 0.0128 0.0175
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0094 0.012 0.0303
Trypanosoma brucei dihydrolipoamide branched chain transacylase, putative 0.0078 0.0093 0.0233
Brugia malayi serine/threonine-protein kinase plk-2 0.0101 0.0133 0.035
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0104 0.0137 0.0361
Schistosoma mansoni aspartate carbamoyltransferase 0.0193 0.0295 0.0293
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.001 0.0035
Echinococcus granulosus epidermal growth factor receptor 0.0088 0.011 0.0151
Brugia malayi hypothetical protein 0.0336 0.0547 0.145
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0035 0.0016 0.0019
Schistosoma mansoni hypothetical protein 0.0082 0.0099 0.0097
Schistosoma mansoni amine GPCR 0.051 0.0854 0.0853
Brugia malayi CXXC zinc finger family protein 0.0032 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0023
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0316 0.0512 0.1308
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni terminal deoxycytidyl transferase 0.0077 0.009 0.0089
Trypanosoma brucei unspecified product 0.0053 0.0048 0.0118
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0202 0.0311 0.0822
Entamoeba histolytica hypothetical protein 0.0191 0.0292 0.464
Loa Loa (eye worm) hypothetical protein 0.0035 0.0016 0.0037
Brugia malayi leucyl aminopeptidase 0.0148 0.0217 0.0571
Schistosoma mansoni tar DNA-binding protein 0.0071 0.008 0.0078
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.2236 0.3902 1
Brugia malayi hypothetical protein 0.025 0.0396 0.1047
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Onchocerca volvulus 0.0145 0.021 0.1303
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.014 0.0202 0.0833
Brugia malayi hypothetical protein 0.0098 0.0128 0.0336
Onchocerca volvulus Putative nachr subunit 0.0202 0.0311 0.1931
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Schistosoma mansoni hypothetical protein 0.0081 0.0099 0.0097
Echinococcus multilocularis inositol monophosphatase 1 0.0029 0.0005 0.0005
Echinococcus multilocularis neuropeptide FF receptor 2 0.0145 0.021 0.0289
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.009 0.0368
Loa Loa (eye worm) Ulp1 protease 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Toxoplasma gondii propionate-CoA ligase 0.0032 0.001 0.0021
Brugia malayi RNA binding protein 0.0071 0.008 0.0208
Schistosoma mansoni transcription factor btf3 0.0039 0.0023 0.0021
Schistosoma mansoni biogenic amine receptor 0.0145 0.021 0.0209
Echinococcus multilocularis muscleblind protein 0.0294 0.0473 0.0652
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0145 0.021 0.0209
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0016 0.0014
Schistosoma mansoni hypothetical protein 0.045 0.075 0.0748
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0154 0.0153
Onchocerca volvulus 0.0145 0.021 0.1303
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0154 0.3673
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.001 0.0026
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0076 0.009 0.0614
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0104 0.0137 0.0136
Loa Loa (eye worm) hypothetical protein 0.0148 0.0216 0.057
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0083 0.0216
Onchocerca volvulus 0.0202 0.0311 0.1931
Loa Loa (eye worm) hypothetical protein 0.0107 0.0144 0.0379
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0336 0.0547 0.145
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0852 0.1458 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0107 0.0144 0.099
Echinococcus multilocularis mitogen activated protein kinase 11 0.014 0.0202 0.0277
Echinococcus granulosus FTZ F1 alpha 0.0035 0.0016 0.0019
Echinococcus granulosus glycine receptor subunit beta 0.0202 0.0311 0.0428
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0145 0.021 0.0289
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0193 0.0295 0.0293
Echinococcus multilocularis sentrin specific protease 1 0.0027 0.0002 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0145 0.021 0.0289
Echinococcus granulosus epidermal growth factor receptor 0.0164 0.0245 0.0336
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0031 0.0456
Echinococcus multilocularis mitogen activated protein kinase 14 0.014 0.0202 0.0277
Echinococcus multilocularis nAChR subunit 0.0202 0.0311 0.0428
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0145 0.021 0.0209
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0016 0.0019
Echinococcus granulosus sex peptide receptor 0.0145 0.021 0.0289
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0014 0.0012
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0075 0.0087 0.0119
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0032 0.001 0.0035
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0202 0.0311 0.0822
Mycobacterium tuberculosis Probable lipoprotein aminopeptidase LpqL 0.0148 0.0217 0.055
Leishmania major 4-coumarate:coa ligase-like protein 0.0107 0.0144 0.0365
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0202 0.0311 0.0428
Leishmania major carbamoyl-phosphate synthase, putative 0.0193 0.0295 0.075
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0078 0.0093 0.0379
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0113 0.0154 0.039
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.009 0.0226
Brugia malayi hypothetical protein 0.0145 0.021 0.0555
Mycobacterium tuberculosis Probable hydrolase 0.0148 0.0216 0.0548
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Loa Loa (eye worm) hypothetical protein 0.0148 0.0216 0.057
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0015 0.0035
Loa Loa (eye worm) hypothetical protein 0.008 0.0096 0.0252
Schistosoma mansoni RAR-like nuclear receptor 0.0035 0.0016 0.0014
Schistosoma mansoni pyruvate carboxylase 0.0852 0.1458 0.1457
Echinococcus granulosus geminin 0.0374 0.0616 0.0849
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0014 0.0012
Schistosoma mansoni nicalin (M28 family) 0.0148 0.0217 0.0215
Onchocerca volvulus 0.025 0.0396 0.2463
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0098 0.0128 0.0175
Echinococcus granulosus caspase 0.0108 0.0146 0.0199
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0116 0.0159 0.1194
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0145 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0107 0.0144 0.0379
Echinococcus granulosus microtubule associated protein 2 0.314 0.5497 0.76
Schistosoma mansoni glutaminyl-peptide cyclotransferase-related 0.0148 0.0217 0.0215
Onchocerca volvulus 0.0032 0.001 0.0052
Trichomonas vaginalis set domain proteins, putative 0.0262 0.0416 1
Brugia malayi follicle stimulating hormone receptor 0.0145 0.021 0.0555
Schistosoma mansoni tar DNA-binding protein 0.0071 0.008 0.0078
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0032 0.001 0.0035
Trypanosoma cruzi acetyl-CoA carboxylase 0.1384 0.2398 1
Echinococcus multilocularis tar DNA binding protein 0.0071 0.008 0.0108
Loa Loa (eye worm) hypothetical protein 0.0294 0.0473 0.1254
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0098 0.0128 0.0175
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Echinococcus multilocularis allatostatin A receptor 0.0145 0.021 0.0289
Loa Loa (eye worm) hypothetical protein 0.0098 0.0128 0.0336
Brugia malayi AMP-binding enzyme family protein 0.0107 0.0144 0.0379
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0202 0.0311 0.0822
Echinococcus granulosus high affinity choline transporter 1 0.0367 0.0602 0.083
Echinococcus granulosus insulin receptor 0.0052 0.0047 0.0063
Brugia malayi hypothetical protein 0.0191 0.0292 0.0773
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0145 0.021 0.0555
Onchocerca volvulus 0.0262 0.0416 0.2592
Trypanosoma brucei Metacaspase-4 0.0029 0.0006 0.0009
Schistosoma mansoni microsomal glutathione s-transferase 0.0123 0.0172 0.0171
Schistosoma mansoni hypothetical protein 0.0081 0.0097 0.0096
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0202 0.0311 0.0822
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0336 0.0547 0.145
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0104 0.0137 0.0361
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0035 0.0016 0.0014
Loa Loa (eye worm) ACC-1 protein 0.0202 0.0311 0.0822
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0101 0.0133 0.0336
Echinococcus granulosus orexin receptor type 2 0.0145 0.021 0.0289
Loa Loa (eye worm) hypothetical protein 0.0336 0.0547 0.145
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0202 0.0311 0.0309
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0113 0.0154 0.039
Loa Loa (eye worm) hypothetical protein 0.0104 0.0137 0.0361
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0083 0.0113
Mycobacterium ulcerans fatty-acid-CoA ligase 0.008 0.0096 0.0627
Loa Loa (eye worm) hypothetical protein 0.0145 0.021 0.0555
Onchocerca volvulus 0.0148 0.0216 0.1339
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0006 0.0088
Echinococcus granulosus neuropeptide receptor A26 0.0651 0.1105 0.1525
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0038 0.0855
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0023 0.0496
Schistosoma mansoni neuropeptide receptor 0.0145 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0202 0.0311 0.0822
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.0023 0.0328
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0145 0.021 0.0555
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0076 0.0089 0.0225
Schistosoma mansoni high-affinity choline transporter 0.0367 0.0602 0.0601
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0337 0.0549 0.1403
Trypanosoma brucei pyruvate dehydrogenase complex E3 binding protein, putative 0.0078 0.0093 0.0233
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.0302 0.0416
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0113 0.0154 0.039
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.0595 0.1005 0.3572
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0202 0.0311 0.0822
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0035 0.0016 0.0037
Schistosoma mansoni nAChR subunit 0.0098 0.0128 0.0126
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.001 0.0026
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0202 0.0311 0.0822
Echinococcus multilocularis insulin receptor 0.0052 0.0047 0.0063
Echinococcus multilocularis beta LACTamase domain containing family member 0.0148 0.0216 0.0297
Mycobacterium tuberculosis Conserved protein 0.0148 0.0216 0.0548
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0016 0.0014
Mycobacterium leprae Probable biotinylated protein homolog TB7.3 0.0078 0.0093 0.0638
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0217 0.5176
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.009 0.0368

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 10000 nM Concentration of compound causing 50% inhibition of the smooth muscle contractile activity ChEMBL. 11806718
IC50 (binding) = 460 nM Inhibition of the motilin receptor (MTL-R) ChEMBL. 11806718
ND (functional) 0 pA2 (Contractile potency) is the negative logarithm of the molar concentration of antagonist causing a 2-fold shift to the right of the concentration response curve for motilin ; ND is no data ChEMBL. 11806718

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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