Detailed information for compound 331199

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 440.022 | Formula: C20H26ClN3O2S2
  • H donors: 2 H acceptors: 2 LogP: 4.66 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: S/C(=N\Cc1ccc(cc1)C(C)(C)C)/NCc1ccc(cc1Cl)NS(=O)(=O)C
  • InChi: 1S/C20H26ClN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-17(11-18(15)21)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
  • InChiKey: WIYJZLNIOBZPKQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Vanilloid receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0192 0.0418 0.1826
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0023 0.0028 0.0083
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0299 0.0597
Schistosoma mansoni 3-dehydroquinate synthase 0.0243 0.0534 0.1602
Brugia malayi hypothetical protein 0.0019 0.002 0.0087
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0012 0.0004 0.0016
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0021 0.0023 0.0102
Schistosoma mansoni hypothetical protein 0.0088 0.0179 0.0536
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0071 0.031
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0023 0.007
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0021 0.0023 0.003
Loa Loa (eye worm) AUR protein kinase 0.017 0.0366 0.16
Echinococcus granulosus muscleblind protein 0.0629 0.1421 0.4265
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0087 0.026
Onchocerca volvulus 0.0051 0.0094 0.0814
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0059 0.0306
Echinococcus multilocularis neuroglian 0.0023 0.0028 0.0036
Brugia malayi nuclear hormone receptor 0.0041 0.0071 0.031
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0002 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0178 0.0774
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0021 0.0023 0.0097
Echinococcus granulosus dual specificity 0.0192 0.0418 0.1254
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0028 0.0145
Toxoplasma gondii NEK kinase 0.0022 0.0026 0.0026
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0067 0.0201
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0094 0.049
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0021 0.0087
Loa Loa (eye worm) projectin 0.0012 0.0004 0.0016
Echinococcus granulosus importin subunit beta 1 0.0031 0.0047 0.0141
Echinococcus granulosus serine:threonine protein kinase Nek1 0.0017 0.0016 0.0048
Plasmodium falciparum importin beta, putative 0.0031 0.0047 0.0046
Schistosoma mansoni titin 0.0012 0.0004 0.0011
Echinococcus granulosus conserved hypothetical protein 0.0015 0.0011 0.0032
Entamoeba histolytica exonuclease, putative 0.0011 0.0001 0.0005
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.0001 0.0003
Schistosoma mansoni histone deacetylase 1 2 3 0.0419 0.0938 0.2816
Loa Loa (eye worm) hypothetical protein 0.0065 0.0125 0.0546
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0071 0.031
Schistosoma mansoni amine oxidase 0.0065 0.0125 0.0375
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0028 0.0123
Plasmodium vivax glutathione reductase, putative 0.0038 0.0063 0.0063
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.0262 0.1147
Onchocerca volvulus 0.0015 0.0011 0.0063
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0014 0.0041
Trypanosoma brucei histone deacetylase 3 0.1006 0.2288 1
Plasmodium falciparum serine/threonine protein kinase, putative 0.017 0.0366 0.0365
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0095 0.0414
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0116
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0014 0.0013
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0243 0.0534 0.1043
Mycobacterium tuberculosis Conserved protein 0.0021 0.0023 0.0035
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0071 0.0213
Toxoplasma gondii NEK kinase 0.0022 0.0026 0.0026
Brugia malayi Voltage gated chloride channel family protein 0.0021 0.0023 0.0102
Schistosoma mansoni cell adhesion molecule 0.0023 0.0028 0.0083
Toxoplasma gondii patched family protein 0.0019 0.002 0.002
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0028 0.0027
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0137
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0087 0.0111
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0014 0.0059
Schistosoma mansoni cpg binding protein 0.0062 0.0119 0.0357
Brugia malayi Carboxylesterase family protein 0.0034 0.0053 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.004
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0023 0.0102
Toxoplasma gondii IMP dehydrogenas 0.0021 0.0023 0.0023
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0119 0.052
Leishmania major hypothetical protein, conserved 0.0019 0.0019 0.0079
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Brugia malayi glutaminase DH11.1 0.0584 0.1318 0.5762
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0021 0.0023 0.0035
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0111 0.0232 0.1015
Echinococcus granulosus leucine rich repeat containing protein 4 0.0012 0.0004 0.0011
Echinococcus granulosus neuroglian 0.0048 0.0086 0.0258
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.0101 0.01
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0071 0.0609
Loa Loa (eye worm) hypothetical protein 0.0126 0.0265 0.1159
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Giardia lamblia hypothetical protein 0.0011 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0209 0.0456 0.1993
Echinococcus granulosus cpg binding protein 0.0066 0.0127 0.0381
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0175 0.0344
Schistosoma mansoni glutaminase 0.0584 0.1318 0.3956
Echinococcus multilocularis roundabout 2 0.0023 0.0028 0.0036
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0002 0.0003
Plasmodium falciparum protein MAM3, putative 0.0021 0.0023 0.0022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0067 0.035
Echinococcus granulosus serine:threonine kinase SAD 1 0.0049 0.0088 0.0263
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0071 0.0213
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.0305 0.1327
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0021 0.0062
Schistosoma mansoni hypothetical protein 0.0066 0.0128 0.0384
Onchocerca volvulus 0.0019 0.002 0.0147
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0207
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0019 0.0058
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0021 0.0091
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0094 0.0493
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0023 0.0028 0.0036
Giardia lamblia Kinase, NEK 0.0022 0.0026 0.0133
Echinococcus granulosus nephrin 0.0012 0.0004 0.0011
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0028 0.0028
Schistosoma mansoni DNA polymerase IV / kappa 0.0034 0.0054 0.0163
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0053 0.0159
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0046 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.005 0.0262
Brugia malayi latrophilin 2 splice variant baaae 0.0143 0.0304 0.1329
Leishmania major mitochondrial DNA polymerase beta 0.0302 0.067 0.2927
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0023 0.0102
Brugia malayi Myb-like DNA-binding domain containing protein 0.0012 0.0004 0.0016
Echinococcus multilocularis hemicentin 1 0.0023 0.0028 0.0036
Trichomonas vaginalis histone deacetylase, putative 0.0836 0.1897 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0071 0.031
Brugia malayi Histone deacetylase family protein 0.1006 0.2288 1
Entamoeba histolytica protein kinase domain containing protein 0.017 0.0366 0.1929
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0026 0.0133
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0006 0.0006
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0305 0.1331
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0021 0.0023 0.0017
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0021 0.0023 0.003
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0006 0.0028
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0067 0.0201
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0178 0.0774
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0008 0.004
Schistosoma mansoni titin 0.0023 0.0028 0.0083
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0263 0.058 0.1741
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0481
Echinococcus multilocularis intestinal type alkaline phosphatase 0.017 0.0366 0.047
Loa Loa (eye worm) hypothetical protein 0.0066 0.0128 0.0559
Schistosoma mansoni rotamase 0.0032 0.005 0.0151
Loa Loa (eye worm) hypothetical protein 0.0065 0.0125 0.0546
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Schistosoma mansoni apoptosis regulator bax 0.0086 0.0175 0.0524
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0015 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0292 0.0375
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Leishmania major 4-coumarate:coa ligase-like protein 0.0123 0.0258 0.1124
Schistosoma mansoni flap endonuclease-1 0.0049 0.0088 0.0264
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0237 0.071
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.067 0.293
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0027 0.0034
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.0128 0.0384
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0279 0.0836
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0237 0.1244
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0054 0.01 0.0432
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0036 0.0059 0.0053
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0282 0.0625 0.273
Echinococcus multilocularis Niemann Pick C1 protein 0.0451 0.1014 0.1301
Brugia malayi loechrig isoform VII 0.0229 0.0503 0.2201
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0054 0.0232
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Echinococcus granulosus BC026374 protein S09 family 0.0034 0.0053 0.0159
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0197 0.0388
Schistosoma mansoni chloride channel protein 0.0021 0.0023 0.007
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0241
Mycobacterium tuberculosis Conserved hypothetical protein 0.011 0.0228 0.0452
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.011 0.0228 0.0684
Schistosoma mansoni ets 0.0011 0.0002 0.0007
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0022 0.0027 0.0116
Echinococcus multilocularis GA binding protein alpha chain 0.0079 0.0158 0.0203
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Trichomonas vaginalis rotamase, putative 0.0032 0.005 0.0262
Brugia malayi polk-prov protein 0.0088 0.0178 0.0779
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0116
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0021 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0088 0.0263
Schistosoma mansoni patched 1 0.0136 0.0288 0.0863
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0028 0.0124
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0102
Brugia malayi Nuclear hormone receptor E75 0.002 0.0021 0.0091
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0137
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.011 0.0228 0.0997
Brugia malayi Histone deacetylase family protein 0.1006 0.2288 1
Echinococcus granulosus replication factor c subunit 1 0.0031 0.0047 0.0142
Echinococcus multilocularis histone deacetylase 6 0.1024 0.2331 0.2991
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.0059 0.0072
Toxoplasma gondii PfMNL-2 CISD1 family iron-sulfur protein, putative 0.0015 0.0011 0.001
Echinococcus multilocularis hemicentin 1 0.0023 0.0028 0.0036
Echinococcus multilocularis exonuclease 1 0.0011 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0638 0.3361
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0021 0.0023 0.003
Echinococcus granulosus histone deacetylase 6 0.1006 0.2288 0.6865
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0036 0.0059 0.0252
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0059
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.031
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Leishmania major hypothetical protein, conserved 0.0055 0.0101 0.0438
Mycobacterium tuberculosis Possible oxidoreductase 0.0065 0.0125 0.0242
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0008 0.004
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0011 0.0001 0.0001
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.0047 0.0245
Echinococcus granulosus titin 0.0012 0.0004 0.0011
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0282 0.0625 0.273
Brugia malayi RNA binding protein 0.0132 0.0279 0.1218
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0114
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0036 0.0058 0.0175
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0059 0.0252
Giardia lamblia Kinase, CAMK CAMKL 0.0049 0.0088 0.0458
Brugia malayi hypothetical protein 0.0034 0.0053 0.0232
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0181 0.0784
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0292 0.0876
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0263 0.058 0.0744
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0071 0.0213
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0049 0.0256
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0059 0.0053
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0059 0.0107
Toxoplasma gondii histone kinase SNF1, putative 0.0049 0.0088 0.0087
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0014 0.0059
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.0262 0.1147
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0047 0.0085 0.0085
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0071 0.0213
Echinococcus multilocularis neuroglian 0.0048 0.0086 0.011
Plasmodium vivax flap endonuclease 1, putative 0.0054 0.01 0.01
Brugia malayi DKFZp564C0469 protein 0.0031 0.0047 0.0207
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0022 0.0027 0.0139
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.0087 0.0111
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0207
Giardia lamblia Flap structure-specific endonuclease 0.0054 0.01 0.0524
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.215 0.4919 1
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0117 0.0351
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0638 0.3361
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0061 0.0061
Schistosoma mansoni hemicentin 0.0012 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.031
Loa Loa (eye worm) hypothetical protein 0.0036 0.0058 0.0254
Leishmania major serine/threonine-protein kinase, putative 0.0022 0.0026 0.0108
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.0087 0.0111
Schistosoma mansoni histone deacetylase hda2 0.0419 0.0938 0.2816
Echinococcus granulosus GPCR family 2 0.0066 0.0128 0.0384
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0049 0.0088 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0071 0.031
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0015 0.0011 0.001
Brugia malayi Ets-domain containing protein 0.0079 0.0158 0.069
Entamoeba histolytica Flap nuclease, putative 0.0054 0.01 0.0526
Echinococcus granulosus geminin 0.0175 0.0379 0.1138
Schistosoma mansoni hypothetical protein 0.0131 0.0276 0.0829
Onchocerca volvulus 0.0036 0.0059 0.0498
Brugia malayi hypothetical protein 0.0126 0.0265 0.1159
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0021 0.0023 0.0205
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0021 0.003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0008 0.004
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0021 0.002
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0061 0.0115 0.0115
Echinococcus granulosus histone deacetylase 6 0.1006 0.2288 0.6865
Loa Loa (eye worm) hypothetical protein 0.0419 0.0938 0.4102
Plasmodium vivax JmjC domain containing protein 0.0016 0.0014 0.0013
Leishmania major guanosine monophosphate reductase 0.0021 0.0023 0.0097
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0282 0.0846
Echinococcus granulosus Protein patched homolog 1 0.0136 0.0288 0.0863
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0006 0.0026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0071 0.0213
Loa Loa (eye worm) hypothetical protein 0.0065 0.0125 0.0546
Plasmodium vivax histone deacetylase, putative 0.1006 0.2288 0.2287
Giardia lamblia DNA damage repair protein 0.0034 0.0054 0.0282
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0638 0.3361
Echinococcus multilocularis geminin 0.0175 0.0379 0.0486
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0123 0.0258 0.0479
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0132 0.0279 0.1218
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0012 0.0004 0.0011
Toxoplasma gondii histone deacetylase HDAC4 0.0419 0.0938 0.0938
Brugia malayi protein unc-22 0.0016 0.0014 0.006
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0049 0.0088 0.0382
Echinococcus multilocularis replication factor c subunit 1 0.0031 0.0047 0.0061
Brugia malayi TAR-binding protein 0.0132 0.0279 0.1218
Trypanosoma cruzi UDP-galactopyranose mutase 0.0065 0.0125 0.0545
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0046 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Echinococcus granulosus para nitrobenzyl esterase 0.0034 0.0053 0.0159
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0123 0.0258 0.0513
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0086 0.0175 0.0763
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0241
Schistosoma mansoni nuclear receptor 0.002 0.0021 0.0062
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0022 0.0027 0.008
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0023 0.003
Brugia malayi jmjC domain containing protein 0.0061 0.0117 0.0511
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0381 0.0851 0.0846
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0054 0.0236
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0021 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0008 0.004
Entamoeba histolytica acyl-CoA synthetase, putative 0.0123 0.0258 0.136
Echinococcus multilocularis insulin growth factor binding 0.0012 0.0004 0.0005
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0015 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) histone deacetylase 1 0.0836 0.1897 0.8291
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0002 0.001
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0067 0.0201
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0059 0.0053
Entamoeba histolytica exonuclease, putative 0.0011 0.0001 0.0005
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Schistosoma mansoni cell adhesion molecule 0.0023 0.0028 0.0083
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0014 0.0059
Schistosoma mansoni chloride channel protein 0.0021 0.0023 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0087 0.026
Echinococcus granulosus casein kinase ii subunit beta 0.0037 0.0061 0.0183
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0237 0.0522 0.2281
Entamoeba histolytica hypothetical protein 0.0035 0.0057 0.0302
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0027 0.0025
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0174 0.0343
Schistosoma mansoni elf1 0.0011 0.0002 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0026
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0021 0.0062
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0061 0.0265
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0071 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0047 0.0245
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0051 0.0152
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0023 0.012
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0241
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0324 0.0971
Loa Loa (eye worm) hypothetical protein 0.0126 0.0265 0.1159
Schistosoma mansoni titin 0.0012 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0059 0.0257
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0021 0.0027
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0237 0.103
Trypanosoma brucei aurora B kinase 0.017 0.0366 0.1596
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0063 0.0063
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0065 0.0125 0.0124
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0014 0.0041
Trichomonas vaginalis STE family protein kinase 0.0022 0.0026 0.0133
Onchocerca volvulus 0.0019 0.002 0.0147
Onchocerca volvulus 0.0036 0.0059 0.0498
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0059 0.0252
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0026 0.0112
Plasmodium vivax histone deacetylase 1, putative 0.0836 0.1897 0.1897
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0021 0.0023 0.0035
Schistosoma mansoni hypothetical protein 0.0086 0.0175 0.0524
Plasmodium falciparum histone deacetylase, putative 0.1006 0.2288 0.2287
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0021 0.0092
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0027 0.0139
Schistosoma mansoni zinc finger protein 0.002 0.0021 0.0062
Brugia malayi nuclear receptor NHR-88 0.002 0.0021 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.0128 0.0164
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0087 0.0456
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0002 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0527 0.1187 0.5189
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.0087 0.0379
Loa Loa (eye worm) hypothetical protein 0.0145 0.031 0.1353
Trypanosoma brucei histone deacetylase, putative 0.1006 0.2288 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0071 0.031
Leishmania major histone deacetylase, putative 0.1006 0.2288 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Leishmania major DNA damage repair protein, putative 0.0034 0.0054 0.0232
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0402 0.2114
Leishmania major histone deacetylase, putative 0.0836 0.1897 0.8291
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0021 0.0023 0.0017
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0034 0.0053 0.0159
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0352 0.1534
Treponema pallidum Mg2+ transport protein (mgtE) 0.0021 0.0023 0.0273
Brugia malayi CHE-14 protein 0.0136 0.0288 0.1257
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0037 0.0061 0.0261
Echinococcus granulosus alkaline phosphatase 0.017 0.0366 0.1098
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0087 0.0453
Echinococcus granulosus snurportin 1 0.033 0.0735 0.2205
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0237 0.071
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0028 0.0122
Leishmania major hypothetical protein, conserved 0.0016 0.0014 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0002 0.0007
Trypanosoma brucei unspecified product 0.015 0.0321 0.14
Brugia malayi Prion-like- 0.0023 0.0028 0.0122
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0071 0.0213
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0034 0.0173
Echinococcus granulosus expressed conserved protein 0.0297 0.0658 0.1975
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.0087 0.0374
Brugia malayi Flap endonuclease-1 0.0054 0.01 0.0437
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0006 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0352 0.1534
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.0101 0.0442
Onchocerca volvulus 0.002 0.0021 0.0154
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0071 0.0213
Plasmodium vivax SET domain protein, putative 0.0033 0.0051 0.005
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0021 0.0023 0.0205
Chlamydia trachomatis dehyroquinate synthase 0.0243 0.0534 0.0528
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0181 0.0784
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0229 0.0503 0.1511
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0057 0.0172
Schistosoma mansoni hypothetical protein 0.0266 0.0587 0.1761
Trypanosoma cruzi DNA polymerase kappa, putative 0.0164 0.0352 0.1538
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0237 0.071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0071 0.031
Echinococcus multilocularis histone deacetylase 6 0.1006 0.2288 0.2935
Echinococcus multilocularis tyrosine protein kinase otk 0.0023 0.0028 0.0036
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0243 0.0534 0.0528
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0006 0.0005
Brugia malayi nuclear receptor RXR 0.0022 0.0026 0.0114
Brugia malayi Csnk2b protein 0.0037 0.0061 0.0266
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0021 0.0023 0.0035
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0026 0.0114
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0022 0.0026 0.0108
Brugia malayi Protein kinase domain containing protein 0.0192 0.0418 0.1826
Leishmania major chloride channel protein, putative 0.0021 0.0023 0.0097
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0002 0.0003
Trypanosoma brucei unspecified product 0.0076 0.015 0.065
Loa Loa (eye worm) TAR-binding protein 0.0132 0.0279 0.1218
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.0101 0.0442
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0008 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0054 0.0236
Echinococcus multilocularis casein kinase ii subunit beta 0.0037 0.0061 0.0078
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0045 0.0135
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.011 0.0228 0.0684
Schistosoma mansoni alkaline phosphatase 0.017 0.0366 0.1098
Leishmania major DNA polymerase eta, putative 0.0136 0.0289 0.1259
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0125 0.0547
Schistosoma mansoni neuroligin 3 (S09 family) 0.0034 0.0053 0.0159
Brugia malayi Peroxidasin 0.0023 0.0028 0.0122
Schistosoma mansoni terminal deoxycytidyl transferase 0.011 0.0228 0.0684
Onchocerca volvulus Protein patched homolog 0.0019 0.002 0.0147
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0071 0.0213
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Schistosoma mansoni ran 0.0023 0.0028 0.0085
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0049 0.0088 0.0378
Loa Loa (eye worm) disorganized muscle protein 1 0.0012 0.0004 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0071 0.031
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.0006 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0071 0.031
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0034 0.0053 0.0068
Leishmania major hypothetical protein, conserved 0.0111 0.0232 0.101
Echinococcus multilocularis acetylcholinesterase 0.0198 0.0432 0.0555
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0023 0.0068
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0197 0.0388
Trichomonas vaginalis set domain proteins, putative 0.0249 0.0547 0.2882
Leishmania major DNA polymerase kappa, putative 0.0034 0.0054 0.0232
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0023 0.0102
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0061 0.0516
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0071 0.0213
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0067 0.0293
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0074 0.0321
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0036 0.0059 0.0053
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0006 0.0022
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0028 0.0124
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0023 0.0098
Schistosoma mansoni cell adhesion molecule 0.0012 0.0004 0.0011
Echinococcus granulosus defective proboscis extension response 0.0036 0.0058 0.0175
Loa Loa (eye worm) chloride channel protein 7 0.0021 0.0023 0.0102
Brugia malayi Thioredoxin reductase 0.0038 0.0063 0.0275
Brugia malayi hypothetical protein 0.0035 0.0057 0.0251
Echinococcus multilocularis 0.0012 0.0004 0.0005
Echinococcus multilocularis snurportin 1 0.033 0.0735 0.0943
Schistosoma mansoni nephrin 0.0023 0.0028 0.0083
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0094 0.0493
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0019 0.0083
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0014 0.0017
Trypanosoma cruzi DNA polymerase eta, putative 0.0136 0.0289 0.1263
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Echinococcus multilocularis Immunoglobulin 0.0036 0.0058 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Brugia malayi hypothetical protein 0.0036 0.0058 0.0254
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Trichomonas vaginalis AGC family protein kinase 0.017 0.0366 0.1927
Echinococcus multilocularis GPCR, family 2 0.0066 0.0128 0.0164
Loa Loa (eye worm) runx1 0.0055 0.0102 0.0445
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0207
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0059 0.0256
Entamoeba histolytica hypothetical protein 0.0035 0.0057 0.0302
Giardia lamblia Exonuclease 1 0.0011 0.0001 0.0002
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0019 0.0083
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0008 0.0031
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0027 0.0137
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0014 0.0017
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0174 0.0308
Toxoplasma gondii NEK kinase 0.0022 0.0026 0.0026
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0021 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0352 0.1534
Brugia malayi jmjC domain containing protein 0.0016 0.0014 0.0059
Brugia malayi ecdysone receptor 0.002 0.0021 0.0091
Echinococcus granulosus titin 0.0016 0.0014 0.0041
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0192 0.0418 0.1822
Toxoplasma gondii ATPase, AAA family protein 0.0031 0.0047 0.0047
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.0391 0.3505
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0117 0.015
Brugia malayi Prion-like- 0.0012 0.0004 0.0016
Onchocerca volvulus 0.0019 0.002 0.0147
Echinococcus multilocularis carboxylesterase 5A 0.0198 0.0432 0.0555
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0028 0.0122
Trypanosoma brucei histone deacetylase 1 0.0836 0.1897 0.8291
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0063 0.0274
Entamoeba histolytica acyl-coA synthetase, putative 0.0123 0.0258 0.136
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0243 0.0534 0.1074
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0026 0.0133
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0014 0.0041
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0012 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0065 0.0125 0.0546
Plasmodium falciparum chorismate synthase 0.4361 1 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.011 0.0228 0.0293
Loa Loa (eye worm) hypothetical protein 0.0036 0.0058 0.0254
Brugia malayi RE40412p 0.0015 0.0011 0.0047
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.031
Brugia malayi Prion-like- 0.0012 0.0004 0.0016
Loa Loa (eye worm) carboxylesterase 0.0034 0.0053 0.0232
Echinococcus granulosus BRCA1 associated protein 0.0019 0.0019 0.0058
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0111 0.0232 0.122
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Trypanosoma cruzi leucine rich repeat protein, putative 0.0014 0.0008 0.0036
Loa Loa (eye worm) hypothetical protein 0.0123 0.0258 0.1129
Schistosoma mansoni hypothetical protein 0.0024 0.0032 0.0097
Plasmodium falciparum lipid/sterol:H+ symporter 0.0019 0.002 0.0019
Schistosoma mansoni protein kinase subunit beta 0.006 0.0113 0.034
Echinococcus multilocularis histone deacetylase 6 0.1006 0.2288 0.2935
Schistosoma mansoni septate junction protein 0.0023 0.0028 0.0083
Schistosoma mansoni protein kinase subunit gamma 0.0229 0.0503 0.1511
Brugia malayi CXXC zinc finger family protein 0.0062 0.0119 0.052
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.0625 0.329
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0232
Loa Loa (eye worm) patched family protein 0.0019 0.002 0.0087
Onchocerca volvulus 0.0036 0.0059 0.0498
Entamoeba histolytica protein kinase, putative 0.0192 0.0418 0.2201
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0022 0.0027 0.008
Entamoeba histolytica hypothetical protein 0.0192 0.0418 0.2201
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0037 0.0061 0.0061
Toxoplasma gondii histone deacetylase HDAC1 0.1006 0.2288 0.2287
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0288 0.1513
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0094 0.041
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0036 0.0059 0.0107
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0021 0.0027
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0123 0.0258 0.1129
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0054 0.0054
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0047 0.0047
Echinococcus multilocularis dual specificity 0.0192 0.0418 0.0536
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0036 0.0059 0.0107
Echinococcus granulosus sterol regulatory element binding protein 0.0136 0.0288 0.0863
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.004
Brugia malayi transcription factor E74 isoform 0.0011 0.0002 0.001
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Echinococcus granulosus H:Cl exchange transporter 4 0.0021 0.0023 0.007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0005
Echinococcus granulosus hemicentin 1 0.0023 0.0028 0.0083
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0047 0.0084
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0381 0.0851 1
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0021 0.0091
Loa Loa (eye worm) AUR protein kinase 0.017 0.0366 0.16
Brugia malayi intracellular kinase 0.0051 0.0094 0.041
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0071 0.0091
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0175 0.0344
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0021 0.0154
Plasmodium falciparum DNA repair protein REV1, putative 0.0034 0.0054 0.0053
Echinococcus multilocularis tar DNA binding protein 0.0132 0.0279 0.0357
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0067 0.0353
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.215 0.4919 1
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0424 0.2235
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0071 0.0213
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Treponema pallidum fructose-bisphosphate aldolase 0.0288 0.0638 0.7494
Loa Loa (eye worm) hypothetical protein 0.0123 0.0258 0.1129
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0034 0.0053 0.0096
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0237 0.0522 0.1566
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Toxoplasma gondii LsmAD domain-containing protein 0.0055 0.0101 0.0101
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0059 0.0256
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Toxoplasma gondii histone deacetylase HDAC5 0.0419 0.0939 0.0939
Plasmodium vivax DNA repair protein RAD2, putative 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0074 0.0317
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0071 0.0091
Trypanosoma brucei DNA polymerase IV, putative 0.0164 0.0352 0.1534
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0021 0.0023 0.007
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0036 0.0059 0.0257
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Loa Loa (eye worm) carboxylesterase 0.0198 0.0432 0.1889
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0123 0.0258 0.0513
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0122
Echinococcus multilocularis nibrin 0.0031 0.0047 0.0061
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0012 0.0004 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0036 0.0059 0.0053
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0087 0.0379
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0192 0.0418 0.1825
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0022 0.0026 0.0112
Mycobacterium tuberculosis Carboxylesterase LipT 0.0034 0.0053 0.0096
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0237 0.2778
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0001 0.0002
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0031 0.0047 0.0049
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0065 0.0125 0.0207
Brugia malayi hypothetical protein 0.002 0.0021 0.0091
Brugia malayi Niemann-Pick C1 protein precursor 0.0316 0.0702 0.3069
Brugia malayi hypothetical protein 0.0158 0.0338 0.1479
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0046 0.004
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0001 0.0001
Trypanosoma brucei trypanothione reductase 0.0038 0.0063 0.027
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0069 0.0134 0.0133
Trypanosoma cruzi protein kinase, putative 0.0017 0.0016 0.0069
Entamoeba histolytica acyl-CoA synthetase, putative 0.0123 0.0258 0.136
Trichomonas vaginalis glutaminase, putative 0.0584 0.1318 0.6948
Toxoplasma gondii serine/threonine specific protein phosphatase 0.0014 0.0008 0.0008
Mycobacterium ulcerans transcriptional regulator 0.0021 0.0023 0.0017
Brugia malayi tailless protein 0.002 0.0021 0.0091
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0059 0.0257
Loa Loa (eye worm) RecQ helicase 0.0021 0.0023 0.0103
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0006 0.0026
Toxoplasma gondii hypothetical protein 0.0049 0.0088 0.0088
Trypanosoma cruzi DNA polymerase kappa, putative 0.0164 0.0352 0.1538
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0071 0.031
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0023 0.007
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0023 0.012
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0022 0.0026 0.0108
Loa Loa (eye worm) hypothetical protein 0.0436 0.0979 0.4281
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0046 0.0543
Giardia lamblia Fructose-bisphosphate aldolase 0.0288 0.0638 0.3361
Brugia malayi CBS domain containing protein 0.0021 0.0023 0.0102
Onchocerca volvulus 0.0436 0.0979 0.8829
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0122
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.0087 0.0086
Entamoeba histolytica protein kinase , putative 0.017 0.0366 0.1929
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0279 0.0836
Echinococcus granulosus flap endonuclease GEN 1 0.0011 0.0001 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0011 0.001
Onchocerca volvulus 0.002 0.0021 0.0154
Loa Loa (eye worm) hypothetical protein 0.0836 0.1897 0.8291
Loa Loa (eye worm) hypothetical protein 0.0606 0.1368 0.5982
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0036 0.0059 0.0072
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0623 0.1409 0.283
Loa Loa (eye worm) hypothetical protein 0.0036 0.0058 0.0254
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0036 0.0059 0.0107
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.0128 0.0559
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0049 0.0088 0.0378
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0019 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0123 0.0258 0.0252
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0014 0.0059
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0071 0.0213
Onchocerca volvulus 0.0033 0.0051 0.0425
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0022 0.0027 0.0034
Brugia malayi chloride channel protein 7 0.0021 0.0023 0.0102
Brugia malayi serine/threonine kinase 12 0.017 0.0366 0.16
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0008 0.004
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.0087 0.026
Chlamydia trachomatis Mg++ transporter 0.0021 0.0023 0.0017
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.0014 0.0019
Trypanosoma cruzi histone deacetylase, putative 0.0419 0.0938 0.4102
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0012 0.0004 0.0016
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0061 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0352 0.1534
Loa Loa (eye worm) casein kinase II 0.0011 0.0001 0.0003
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0002 0.0003
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0299 0.0293
Chlamydia trachomatis protoporphyrinogen oxidase 0.0065 0.0125 0.0119
Echinococcus granulosus flap endonuclease 1 0.0054 0.01 0.03
Brugia malayi hypothetical protein 0.002 0.0021 0.0091
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0092 0.0187 0.0817
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0123 0.0258 0.0252
Loa Loa (eye worm) XPG I-region family protein 0.0011 0.0001 0.0005
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0021 0.0087
Echinococcus granulosus dna polymerase kappa 0.0164 0.0352 0.1056
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0021 0.0023 0.0097
Plasmodium falciparum acyl-CoA synthetase 0.0092 0.0187 0.0186
Echinococcus multilocularis histone deacetylase 3 0.0836 0.1897 0.2434
Onchocerca volvulus 0.0158 0.0338 0.3029
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0036 0.0059 0.0107
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.0625 0.329
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0023 0.012
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0011
Schistosoma mansoni hypothetical protein 0.0066 0.0128 0.0384
Toxoplasma gondii IQ calmodulin-binding motif domain-containing protein 0.0014 0.0008 0.0008
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0036 0.0059 0.0309
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0279 0.0836
Schistosoma mansoni hypothetical protein 0.0011 0.0002 0.0007
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0036 0.0059 0.0075
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.0094 0.0281
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0066 0.0127 0.0127
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0022
Schistosoma mansoni slit 0.0012 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Schistosoma mansoni acetyl-CoA synthetase 0.0036 0.0059 0.0177
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.0047 0.0245
Brugia malayi topoisomerase 0.0031 0.0047 0.0207
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0028 0.0119
Brugia malayi conserved hypotetical protein 0.002 0.0021 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.0128 0.0164
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0047 0.0201
Brugia malayi Importin beta-1 subunit 0.0031 0.0047 0.0206
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0086 0.0175 0.0224
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0002 0.001
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0065 0.0125 0.0375
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0031 0.0047 0.0487
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0027 0.008
Brugia malayi Carboxylesterase family protein 0.0198 0.0432 0.1889
Entamoeba histolytica hypothetical protein 0.0031 0.0047 0.0248
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0026
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0012 0.0004 0.0011
Plasmodium falciparum replication factor C subunit 1, putative 0.0031 0.0047 0.0046
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0022 0.0026 0.0026
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.031
Schistosoma mansoni histone deacetylase 4 5 0.1006 0.2288 0.6865
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0352 0.1534
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0402 0.2114
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0067 0.0293
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0175 0.0344
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0006 0.0028
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.007 0.0068
Toxoplasma gondii patched family protein 0.0019 0.002 0.002
Onchocerca volvulus 0.0034 0.0053 0.0446
Plasmodium falciparum histone deacetylase 1 0.0836 0.1897 0.1896
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.004
Schistosoma mansoni BC026374 protein (S09 family) 0.0034 0.0053 0.0159
Brugia malayi RNA recognition motif domain containing protein 0.0132 0.0279 0.1218
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0008 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Trypanosoma cruzi histone deacetylase 1, putative 0.0836 0.1897 0.8291
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0049 0.0212
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0064 0.0192
Entamoeba histolytica DNA-repair protein, putative 0.0011 0.0001 0.0005
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0019 0.0079
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0237 0.1034
Plasmodium vivax serine/threonine protein kinase 6, putative 0.017 0.0366 0.0366
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.017 0.0366 0.1929
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0049 0.0088 0.0087
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0137 0.0292 0.1276
Treponema pallidum DNA ligase (lig) 0.0031 0.0047 0.0553
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.0094 0.0405
Loa Loa (eye worm) hypothetical protein 0.0092 0.0187 0.0817
Echinococcus multilocularis aurora kinase A 0.017 0.0366 0.047
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0034 0.0173
Trypanosoma cruzi histone deacetylase, putative 0.1006 0.2288 1
Giardia lamblia Histone deacetylase 0.0836 0.1897 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0258 0.0252
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0229 0.0503 0.2651
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0012 0.0004 0.0016
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0064 0.0082
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0094 0.049
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0002 0.0007
Toxoplasma gondii hypothetical protein 0.0019 0.002 0.002
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0086 0.0175 0.0524
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0036 0.0058 0.0175
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0207
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0065 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0086 0.0175 0.0763
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Onchocerca volvulus 0.0123 0.0258 0.2303
Brugia malayi hypothetical protein 0.0065 0.0125 0.0546
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.033 0.0735 0.3212
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0051 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0352 0.1534
Giardia lamblia Casein kinase II beta chain 0.0037 0.0061 0.0317
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0258 0.0252
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0011
Echinococcus multilocularis dnaJ subfamily B 0.0886 0.2011 0.2581
Mycobacterium tuberculosis Conserved protein 0.0021 0.0023 0.0035
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0026 0.0114
Schistosoma mansoni hypothetical protein 0.0066 0.0128 0.0384
Echinococcus multilocularis ets variant gene 4 0.0011 0.0002 0.0003
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0071 0.0091
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0023 0.0022
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0111 0.0232 0.101
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.092 0.2091 0.2086
Brugia malayi nuclear receptor NHR-88 0.0041 0.0071 0.031
Onchocerca volvulus 0.0476 0.107 0.9652
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0049 0.0088 0.0378
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) Csnk2b protein 0.0037 0.0061 0.0266
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0023 0.0028 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0031 0.0047 0.0041
Echinococcus granulosus phd:f box containing protein 0.0016 0.0014 0.0041
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0094 0.049
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0021 0.0023 0.0017
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.017 0.0366 0.1929
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0481
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0102
Trichomonas vaginalis rotamase, putative 0.0032 0.0049 0.0253
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0028 0.0036
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0206
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0046 0.0082 0.0247
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0059 0.0053
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0237 0.1247
Echinococcus multilocularis expressed conserved protein 0.0297 0.0658 0.0844
Onchocerca volvulus 0.0107 0.0221 0.1965
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0123 0.0259 0.1126
Loa Loa (eye worm) hypothetical protein 0.0316 0.0702 0.3069
Trichomonas vaginalis flap endonuclease-1, putative 0.0054 0.01 0.0524
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0071 0.0609
Loa Loa (eye worm) glutaminase 2 0.0584 0.1318 0.5762
Echinococcus granulosus insulin growth factor binding 0.0012 0.0004 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0046 0.0045
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0011 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0181 0.0391 0.1709
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0352 0.1534
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0047
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0002 0.001
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0001 0.0001
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0123 0.0258 0.0252
Echinococcus multilocularis histone deacetylase 8 0.0419 0.0938 0.1204
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0021 0.0062
Brugia malayi Patched related family protein 4 0.0019 0.002 0.0087
Echinococcus granulosus aurora kinase A 0.017 0.0366 0.1099
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0258 0.0252
Trypanosoma brucei unspecified product 0.0076 0.015 0.065
Echinococcus multilocularis protein C ets 2 0.0011 0.0002 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0087 0.0453
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0071 0.031
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0174 0.0343
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0021 0.0023 0.007
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0092 0.0187 0.0181
Loa Loa (eye worm) hypothetical protein 0.0587 0.1325 0.5793
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0061 0.006
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0034 0.0053 0.0276
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0067 0.0086
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0123 0.0258 0.0479
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0623 0.1409 0.1404
Mycobacterium ulcerans glutaminase 0.0584 0.1318 0.1313
Brugia malayi Calcitonin receptor-like protein seb-1 0.0209 0.0456 0.1993
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0023 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Trichomonas vaginalis spcc417.12 protein, putative 0.0034 0.0053 0.0276
Leishmania major hypothetical protein, conserved 0.0019 0.0019 0.0079
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0125 0.0125
Echinococcus multilocularis titin 0.0012 0.0004 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0026 0.0133
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0114
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0125 0.0125
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0014 0.0054
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0002 0.0007
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0023 0.0023
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0023 0.0102
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0125 0.0376
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0071 0.031
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.0094 0.0094
Plasmodium vivax ataxin-2 like protein, putative 0.0055 0.0101 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0259 0.1126
Entamoeba histolytica protein kinase, putative 0.0192 0.0418 0.2201
Brugia malayi hypothetical protein 0.0019 0.002 0.0087
Brugia malayi histone deacetylase 3 (HD3) 0.0836 0.1897 0.8291
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.0625 0.329
Plasmodium vivax chorismate synthase 0.4361 1 1
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0002 0.0007
Mycobacterium ulcerans chorismate synthase 0.4361 1 1
Echinococcus granulosus tar DNA binding protein 0.0132 0.0279 0.0836
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0046 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0192 0.0418 0.1254
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0023 0.007
Brugia malayi ImpB/MucB/SamB family protein 0.011 0.0228 0.0997
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0023 0.0097
Schistosoma mansoni nuclear hormone receptor 0.002 0.0021 0.0062
Brugia malayi hypothetical protein 0.0022 0.0026 0.0114
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.0638 0.3363
Onchocerca volvulus Alicorn homolog 0.0097 0.02 0.1773
Onchocerca volvulus 0.0031 0.0047 0.0394
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0028 0.0122
Schistosoma mansoni titin 0.0012 0.0004 0.0011
Echinococcus granulosus intestinal type alkaline phosphatase 0.017 0.0366 0.1098
Schistosoma mansoni gliotactin 0.0034 0.0053 0.0159
Schistosoma mansoni protein kinase subunit beta 0.0014 0.0008 0.0025
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0023 0.003
Schistosoma mansoni alkaline phosphatase 0.017 0.0366 0.1098
Echinococcus granulosus contactin 0.0023 0.0028 0.0083
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0087 0.0453
Schistosoma mansoni cell adhesion molecule 0.0046 0.0082 0.0247
Giardia lamblia Replication factor C, subunit 1 0.0031 0.0047 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0088 0.0263
Echinococcus granulosus expressed protein 0.0032 0.005 0.0151
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0209 0.0456 0.1993
Schistosoma mansoni acetylcholinesterase 0.0034 0.0053 0.0159
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0054 0.01 0.01
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0028 0.0122
Brugia malayi Prion-like- 0.0012 0.0004 0.0016
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0021 0.0027
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0071 0.031
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.067 0.293
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.001
Toxoplasma gondii histone lysine-specific demethylase 0.0065 0.0125 0.0125
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0059 0.0256
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0071 0.031
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0381 0.0851 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0638 0.3361
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0001 0.0004
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0037 0.0061 0.0261
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.0625 0.329
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.004
Treponema pallidum NADH oxidase 0.0013 0.0006 0.0069
Echinococcus granulosus neuroglian 0.0023 0.0028 0.0083
Schistosoma mansoni hypothetical protein 0.0011 0.0002 0.0007
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.0047 0.0202
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0137
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.0221
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0079 0.0158 0.069
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0036 0.0058 0.0075
Leishmania major 4-coumarate:coa ligase-like protein 0.0123 0.0258 0.1124
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0036 0.0059 0.0107
Onchocerca volvulus Glucosylceramidase homolog 0.0185 0.0402 0.36
Toxoplasma gondii zinc finger cdgsh type protein 0.0015 0.0011 0.001
Trichomonas vaginalis DNA polymerase eta, putative 0.0164 0.0352 0.1852
Trypanosoma cruzi FHA domain containing protein, putative 0.0031 0.0047 0.0206
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.031
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0021 0.0023 0.0102
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0067 0.0086
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0021 0.0027
Echinococcus multilocularis serine:threonine protein kinase Nek1 0.0017 0.0016 0.002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0028 0.0122
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.0625 0.329
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0544 0.1227 0.3683
Schistosoma mansoni neuroglian 0.0023 0.0028 0.0083
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0059 0.0257
Echinococcus multilocularis titin 0.0012 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0021 0.0091
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0018
Brugia malayi XPG I-region family protein 0.0011 0.0001 0.0005
Schistosoma mansoni ran 0.0023 0.0028 0.0085
Loa Loa (eye worm) hypothetical protein 0.0036 0.0058 0.0254
Brugia malayi serine/threonine protein kinase 6 0.017 0.0366 0.16
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0074 0.0321
Mycobacterium ulcerans DNA polymerase IV 0.0164 0.0352 0.0346
Brugia malayi Muscleblind-like protein 0.0629 0.1421 0.6212
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0071 0.0091
Entamoeba histolytica serine/threonine protein kinase, putative 0.0049 0.0088 0.0461
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0031 0.0047 0.0047
Brugia malayi MH2 domain containing protein 0.0125 0.0262 0.1147
Schistosoma mansoni ap endonuclease 0.002 0.0021 0.0063
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0059 0.0256
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0125 0.0263 0.079
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0023 0.007
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0237 0.1034
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0107 0.0221 0.0965
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0046 0.0046
Mycobacterium ulcerans hypothetical protein 0.0021 0.0023 0.0017
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0011 0.0001 0.0004
Schistosoma mansoni histone deacetylase 0.0836 0.1897 0.5692
Echinococcus granulosus roundabout 2 0.0058 0.011 0.033
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0059 0.0053
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0021 0.0154
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0324 0.1414
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0059 0.0257
Onchocerca volvulus 0.0019 0.002 0.0147
Onchocerca volvulus 0.0036 0.0059 0.0498
Echinococcus multilocularis protein kinase shaggy 0.0051 0.0094 0.012
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0026 0.0034
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0209 0.0456 0.0585
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0116
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0092 0.0187 0.0181
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0019 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0402 0.2114
Schistosoma mansoni hypothetical protein 0.0131 0.0276 0.0829
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0324 0.0415
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0021 0.0091
Trypanosoma cruzi UDP-galactopyranose mutase 0.0065 0.0125 0.0545
Brugia malayi hypothetical protein 0.0022 0.0026 0.0114
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0232
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0022 0.0027 0.0026
Schistosoma mansoni lozenge 0.0055 0.0102 0.0306
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0021 0.0023 0.0035
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.0087 0.0374
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0022 0.0026 0.0108
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0059 0.0053
Brugia malayi hypothetical protein 0.0055 0.0101 0.0443
Trichomonas vaginalis histone deacetylase, putative 0.0836 0.1897 1
Loa Loa (eye worm) one IG domain family member 0.0012 0.0004 0.0016
Echinococcus multilocularis histone deacetylase 0.1006 0.2288 0.2935
Leishmania major DNA polymerase eta, putative 0.0061 0.0115 0.0499
Schistosoma mansoni cell adhesion molecule 0.0012 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0055 0.0101 0.0443
Schistosoma mansoni myosin-binding protein-related 0.0012 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Brugia malayi BRCA1-associated protein 2 containing protein 0.0019 0.0019 0.0084
Brugia malayi putative serine/threonine kinase SADA gamma 0.0049 0.0088 0.0383
Loa Loa (eye worm) histone deacetylase 3 0.0836 0.1897 0.8291
Echinococcus multilocularis microtubule associated protein 2 0.146 0.3332 0.4276
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.0001 0.0004
Brugia malayi histone deacetylase 1 (HD1) 0.0836 0.1897 0.8291
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0021 0.0091
Schistosoma mansoni nuclear receptor 0.002 0.0021 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0047 0.0206
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0021 0.0023 0.0097
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0087 0.0453
Loa Loa (eye worm) CAMK protein kinase 0.0016 0.0014 0.006
Loa Loa (eye worm) hypothetical protein 0.0166 0.0358 0.1563
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0059 0.0053
Loa Loa (eye worm) hypothetical protein 0.0198 0.0432 0.1889
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0071 0.0213
Echinococcus multilocularis protein patched 0.0136 0.0288 0.0369
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0059 0.0107
Plasmodium vivax exonuclease I, putative 0.0011 0.0001 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0054 0.0232
Echinococcus granulosus histone deacetylase 6 0.1024 0.2331 0.6995
Echinococcus multilocularis dna polymerase kappa 0.0164 0.0352 0.0452
Echinococcus granulosus lysine specific histone demethylase 1A 0.0065 0.0125 0.0375
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0011 0.001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Onchocerca volvulus 0.0062 0.0119 0.1042
Mycobacterium ulcerans carboxylesterase, LipT 0.0034 0.0053 0.0047
Brugia malayi phosphofructokinase 0.0113 0.0237 0.1034
Loa Loa (eye worm) hypothetical protein 0.0136 0.0289 0.1264
Trypanosoma cruzi histone deacetylase, putative 0.0419 0.0938 0.4102
Onchocerca volvulus 0.0016 0.0014 0.009
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.005 0.022
Loa Loa (eye worm) hypothetical protein 0.0101 0.0208 0.091
Entamoeba histolytica hypothetical protein 0.0035 0.0057 0.0302
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0023 0.007
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0006 0.0027
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0011
Schistosoma mansoni hypothetical protein 0.0035 0.0057 0.0172
Entamoeba histolytica histone deacetylase, putative 0.0836 0.1897 1
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0012 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0198 0.0432 0.1889
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0197 0.0388
Schistosoma mansoni protein kinase 0.017 0.0366 0.1099
Brugia malayi Animal haem peroxidase family protein 0.0012 0.0004 0.0016
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.0094 0.0094
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0036 0.0059 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0402 0.2114
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0023 0.003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0071 0.031
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0094 0.049
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0028 0.0122
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0023 0.0023
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0014 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0026
Echinococcus granulosus histone deacetylase 0.1006 0.2288 0.6865
Trypanosoma cruzi GMP reductase 0.0021 0.0023 0.0102
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0021 0.0023 0.003
Brugia malayi Leucine Rich Repeat family protein 0.0012 0.0004 0.0016
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.007 0.0363
Entamoeba histolytica Ran family GTPase 0.0023 0.0028 0.0148
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0049 0.0088 0.0382
Echinococcus granulosus cyclin dependent kinase 0.0048 0.0087 0.026
Echinococcus granulosus carboxylesterase 5A 0.0198 0.0432 0.1297
Leishmania major histone deacetylase, putative 0.1006 0.2288 1
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0067 0.035
Schistosoma mansoni topbp1 0.0031 0.0047 0.0142
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0022
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0198 0.0432 0.1297
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0237 0.1034
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.0087 0.026
Echinococcus multilocularis titin 0.0012 0.0004 0.0005
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0092 0.0187 0.0368
Entamoeba histolytica deoxycytidyl transferase, putative 0.011 0.0228 0.1201
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0047 0.0206
Trichomonas vaginalis brca1-associated protein, putative 0.0019 0.0019 0.0098
Brugia malayi jmjC domain containing protein 0.0016 0.0014 0.0059
Mycobacterium ulcerans hypothetical protein 0.0159 0.0342 0.0336
Giardia lamblia Kinase, CAMK CAMKL 0.0049 0.0088 0.0458
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0011 0.001
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0065 0.0125 0.0375
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0086 0.0175 0.0224
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0836 0.1897 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0125 0.0546
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0022 0.0027 0.0026
Echinococcus granulosus roundabout 2 0.0023 0.0028 0.0083
Schistosoma mansoni DNA polymerase eta 0.0136 0.0289 0.0868
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0293
Echinococcus multilocularis protein dispatched 1 0.0155 0.0332 0.0425
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0061 0.032
Toxoplasma gondii zinc finger CDGSH-type domain-containing protein 0.0015 0.0011 0.001
Brugia malayi Protein kinase domain containing protein 0.0048 0.0087 0.0379
Loa Loa (eye worm) hypothetical protein 0.0072 0.0143 0.0623
Toxoplasma gondii hypothetical protein 0.0014 0.0008 0.0008
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0028 0.0028
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0036 0.0059 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Brugia malayi serine/threonine-protein kinase 6 0.017 0.0366 0.16
Loa Loa (eye worm) DR-78 0.002 0.0021 0.0091
Schistosoma mansoni microtubule-associated protein tau 0.146 0.3332 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0071 0.0091
Onchocerca volvulus 0.0101 0.0208 0.185
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0021 0.0091
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0016 0.0014 0.006
Trypanosoma brucei AIR9-like protein 0.0014 0.0008 0.0031
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0343 0.0764 0.334
Echinococcus multilocularis 0.0065 0.0125 0.016
Giardia lamblia DINP protein human, muc B family 0.0123 0.0259 0.1361
Plasmodium falciparum histone deacetylase 2 0.1006 0.2288 0.2287
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0078 0.0235
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0023 0.0102
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0078 0.0408
Echinococcus multilocularis histone deacetylase 7 0.1006 0.2288 0.2935
Loa Loa (eye worm) hypothetical protein 0.0143 0.0304 0.1329
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.0001 0.0004
Schistosoma mansoni hypothetical protein 0.0086 0.0175 0.0524
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0061 0.032
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0049 0.0088 0.0383
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0314 0.0942
Brugia malayi hypothetical protein 0.0019 0.002 0.0087
Trypanosoma cruzi GMP reductase 0.0021 0.0023 0.0102
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0019 0.0083
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0014 0.0012
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0065 0.0125 0.0125
Echinococcus multilocularis muscleblind protein 0.0629 0.1421 0.1824
Leishmania major importin beta-1 subunit, putative 0.0025 0.0034 0.0142
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0034 0.0173
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.031
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0027 0.008
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0006 0.0006
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0061 0.0516
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0137 0.0292 0.1276
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3401 0.7793 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0028 0.0123
Loa Loa (eye worm) hypothetical protein 0.0107 0.0221 0.0965
Echinococcus granulosus H:Cl exchange transporter 3 0.0021 0.0023 0.007
Loa Loa (eye worm) AUR protein kinase 0.017 0.0366 0.16
Plasmodium vivax protein kinase Crk2 0.0048 0.0087 0.0086
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.017 0.0366 0.1929
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0174 0.0343
Loa Loa (eye worm) hypothetical protein 0.0049 0.0088 0.0383
Plasmodium vivax histone deacetylase 2, putative 0.1006 0.2288 0.2287
Echinococcus multilocularis tumor protein p63 0.069 0.1562 0.2005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0102
Trypanosoma brucei DNA polymerase eta, putative 0.0136 0.0289 0.1259
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0071 0.031
Echinococcus multilocularis flap endonuclease 1 0.0054 0.01 0.0128
Trypanosoma cruzi histone deacetylase 1, putative 0.0836 0.1897 0.8291
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0005
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0027 0.0025
Schistosoma mansoni histone deacetylase 0.0836 0.1897 0.5692
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.004
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0046 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Echinococcus granulosus Niemann Pick C1 protein 0.0451 0.1014 0.3042
Loa Loa (eye worm) hypothetical protein 0.0092 0.0187 0.0817
Plasmodium vivax DNA repair protein REV1, putative 0.0034 0.0054 0.0054
Onchocerca volvulus 0.0065 0.0125 0.1097
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0065 0.0125 0.0119
Trypanosoma cruzi histone deacetylase, putative 0.1006 0.2288 1
Schistosoma mansoni gabp alpha 0.0079 0.0158 0.0474
Onchocerca volvulus 0.0015 0.0011 0.0063
Echinococcus granulosus lysine specific histone demethylase 1A 0.0065 0.0125 0.0375
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.007 0.0366
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0036 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Plasmodium vivax acyl-CoA synthetase, putative 0.0092 0.0187 0.0187
Echinococcus granulosus microtubule associated protein 2 0.146 0.3332 1
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0229 0.0503 0.0646
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0021 0.0107
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0209 0.0456 0.1993
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.017 0.0366 0.1098
Loa Loa (eye worm) hypothetical protein 0.0036 0.0058 0.0254
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0237 0.1244
Brugia malayi Patched related family protein 10 0.0019 0.002 0.0087
Mycobacterium ulcerans oxidoreductase 0.0065 0.0125 0.0119
Brugia malayi Carboxylesterase family protein 0.0198 0.0432 0.1889
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0036 0.0059 0.0058
Echinococcus multilocularis twitchin 0.0016 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0036 0.0059 0.0257
Brugia malayi Myosin head containing protein 0.0019 0.002 0.0087
Brugia malayi Pre-SET motif family protein 0.0219 0.0478 0.2091
Schistosoma mansoni chromosome transmission fidelity factor 0.0031 0.0047 0.0142
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0292 0.0876
Leishmania major GTP-binding protein, putative 0.0023 0.0028 0.0119
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0067 0.035
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0023 0.0023
Trypanosoma brucei NIMA-related protein kinase 0.0022 0.0026 0.0108
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0002 0.0007
Brugia malayi cell division control protein 2 homolog 0.0048 0.0087 0.0379
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0197 0.0354
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0023 0.0103
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0088 0.0178 0.0779
Echinococcus multilocularis muscleblind protein 1 0.0629 0.1421 0.1824
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0021 0.0062
Trypanosoma cruzi NIMA-related kinase, putative 0.0022 0.0026 0.0112
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0855 0.1942 0.3941
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0047 0.0201
Schistosoma mansoni hypothetical protein 0.033 0.0735 0.2205
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0049 0.0208
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0067 0.0288
Echinococcus multilocularis protoporphyrinogen oxidase 0.0065 0.0125 0.016
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0047 0.0245
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0074 0.0321
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0046 0.0244
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.017 0.0366 0.047
Leishmania major hypothetical protein, conserved,leucine-rich repeat protein, putative 0.0014 0.0008 0.0031
Onchocerca volvulus Protein patched homolog 0.0019 0.002 0.0147
Brugia malayi glutathione reductase 0.0038 0.0063 0.0275
Schistosoma mansoni chloride channel protein 0.0021 0.0023 0.007
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.0094 0.0093
Toxoplasma gondii histone deacetylase HDAC3 0.0836 0.1897 0.1897
Schistosoma mansoni hypothetical protein 0.0131 0.0276 0.0829
Schistosoma mansoni nuclear hormone receptor 0.002 0.0021 0.0062
Echinococcus multilocularis titin 0.0016 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0122
Echinococcus granulosus acetylcholinesterase 0.0198 0.0432 0.1297
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0292 0.0375
Schistosoma mansoni titin 0.0012 0.0004 0.0011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0028 0.0122
Brugia malayi CLC chloride channel protein 0.0021 0.0023 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Loa Loa (eye worm) carboxylesterase 0.0034 0.0053 0.0232
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0251 0.0552 0.0708
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0023 0.0102
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0071 0.0213
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0023 0.0028 0.0218
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.0625 0.329
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.0342 0.0683
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0023 0.0103
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0036 0.0059 0.0107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0028 0.0122
Schistosoma mansoni septate junction protein 0.0023 0.0028 0.0083
Onchocerca volvulus 0.0249 0.0548 0.4925
Echinococcus granulosus H:Cl exchange transporter 7 0.0021 0.0023 0.007
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0014 0.0042
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0237 0.0522 0.2281
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0071 0.0091
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0125 0.0376
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0402 0.2114
Mycobacterium ulcerans hypothetical protein 0.0021 0.0023 0.0017
Brugia malayi Patched protein homolog 1 0.0019 0.002 0.0087
Echinococcus granulosus protein kinase shaggy 0.0051 0.0094 0.0281
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0036 0.0059 0.0053
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.006 0.0113 0.0146
Echinococcus multilocularis acetylcholinesterase 0.0198 0.0432 0.0555
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0117 0.0351
Schistosoma mansoni ets-related 0.024 0.0528 0.1585
Schistosoma mansoni ap endonuclease 0.002 0.0021 0.0063
Schistosoma mansoni roundabout 0.0023 0.0028 0.0083
Brugia malayi RE40412p 0.0015 0.0011 0.0047
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0012 0.0004 0.0011
Schistosoma mansoni hypothetical protein 0.0131 0.0276 0.0829
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0071 0.0213
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.0638 0.3363
Leishmania major hypothetical protein, conserved 0.0021 0.0023 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0022 0.0027 0.008
Brugia malayi Carboxylesterase family protein 0.0034 0.0053 0.0232
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0237 0.1244
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0023 0.0022
Schistosoma mansoni importin beta-1 0.0031 0.0047 0.0141
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0116
Schistosoma mansoni tyrosine kinase 0.0027 0.0038 0.0115
Trypanosoma brucei PAB1-binding protein , putative 0.0055 0.0101 0.0438
Leishmania major hypothetical protein, unknown function 0.0015 0.0011 0.0042
Toxoplasma gondii CBS family protein 0.0021 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0188 0.0408 0.1782
Loa Loa (eye worm) hypothetical protein 0.0629 0.1421 0.6212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0638 0.3361
Echinococcus multilocularis BC026374 protein (S09 family) 0.0034 0.0053 0.0068
Leishmania major histone deacetylase, putative 0.0836 0.1897 0.8291
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.0087 0.0374
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0028 0.0036
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0237 0.0522 0.067
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.0478 0.2091
Schistosoma mansoni hypothetical protein 0.0015 0.0011 0.0032
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0237 0.0231
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0061 0.032
Brugia malayi ecdysteroid receptor 0.0041 0.0071 0.031
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0071 0.0091
Leishmania major protein kinase, putative 0.017 0.0366 0.1596
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0021 0.0027
Loa Loa (eye worm) hypothetical protein 0.0158 0.0338 0.1479
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.092 0.2091 0.2086
Echinococcus multilocularis histone deacetylase 1 0.0836 0.1897 0.2434
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0122
Toxoplasma gondii patched family protein 0.0019 0.002 0.002
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0258 0.1129
Brugia malayi Histone deacetylase 1 0.0836 0.1897 0.8291
Brugia malayi hypothetical protein 0.0044 0.0078 0.034
Brugia malayi Ets-domain containing protein 0.0079 0.0158 0.069
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0021 0.0023 0.007
Mycobacterium tuberculosis Probable reductase 0.0086 0.0174 0.0343
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0027 0.0026
Trypanosoma brucei protein kinase, putative 0.0051 0.0094 0.0405
Echinococcus granulosus peroxidasin 0.0023 0.0028 0.0083
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0057 0.0074
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.0047 0.0206
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0051 0.0152
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0026 0.0078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0026
Schistosoma mansoni nephrin related 0.0012 0.0004 0.0011
Onchocerca volvulus Tyrosine kinase homolog 0.0493 0.1109 1
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.0094 0.0281
Echinococcus granulosus twitchin 0.0052 0.0096 0.0288
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0067 0.035
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0014 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0232
Loa Loa (eye worm) hypothetical protein 0.0046 0.0082 0.036
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0071 0.0213
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0014 0.0017
Leishmania major inosine-5-monophosphate dehydrogenase 0.0021 0.0023 0.0097
Echinococcus multilocularis sterol regulatory element binding protein 0.0136 0.0288 0.0369
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0014 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0014 0.0041
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.0101 0.01
Plasmodium falciparum thioredoxin reductase 0.0013 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0122
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0021 0.0177
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0237 0.0469
Echinococcus multilocularis cpg binding protein 0.0066 0.0127 0.0163
Trichomonas vaginalis histone deacetylase, putative 0.0836 0.1897 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0087 0.0111
Loa Loa (eye worm) histone deacetylase 7A 0.1006 0.2288 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0174 0.0343
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0026 0.0114
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0006 0.0005
Schistosoma mansoni nephrin 0.0048 0.0086 0.0258
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0175 0.0344
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0047 0.006
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0023 0.003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0292 0.0876
Brugia malayi nuclear receptor NHR-67 0.002 0.0021 0.0091
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0137
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0071 0.0213
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.0028 0.0083
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0136 0.0288 0.1257
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0087 0.0453
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0031 0.0047 0.0207
Echinococcus granulosus lachesin 0.0023 0.0028 0.0083
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.0014 0.0043
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.0094 0.012
Echinococcus multilocularis down syndrome cell adhesion 0.0012 0.0004 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0014 0.006
Brugia malayi protein C24B5.3 0.0019 0.002 0.0087
Plasmodium falciparum protoporphyrinogen oxidase 0.0065 0.0125 0.0124
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0053 0.0159
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0059 0.0107
Echinococcus multilocularis AMPK beta subunit 0.0111 0.0232 0.0298
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0063 0.0116
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0067 0.0086
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.017 0.0366 0.047
Giardia lamblia Hypothetical protein 0.0021 0.0023 0.012
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0014 0.0017
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0086 0.0175 0.0524
Echinococcus multilocularis Protein lozenge 0.0055 0.0102 0.0131
Echinococcus multilocularis para nitrobenzyl esterase 0.0034 0.0053 0.0068
Brugia malayi nuclear receptor RXR 0.002 0.0021 0.0091
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0054 0.0236
Mycobacterium ulcerans DNA polymerase IV 0.0164 0.0352 0.0346
Loa Loa (eye worm) patched family protein 0.0019 0.002 0.0087
Loa Loa (eye worm) hypothetical protein 0.0065 0.0125 0.0546
Brugia malayi histone deacetylase 11 0.0419 0.0938 0.4102
Plasmodium falciparum NIMA related kinase 4 0.0022 0.0026 0.0025
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.0087 0.0374
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0028 0.0036
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0023 0.007
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0122
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0051 0.005
Brugia malayi casein kinase II, putaitve 0.0011 0.0001 0.0003
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.006 0.0113 0.034
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0059 0.0306
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0087 0.0378
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0067 0.0288
Mycobacterium ulcerans dehydrogenase 0.0065 0.0125 0.0119
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0059
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0054 0.0236
Loa Loa (eye worm) hypothetical protein 0.0092 0.0187 0.0817
Schistosoma mansoni hypothetical protein 0.0175 0.0379 0.1138
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0071 0.0091
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0006 0.0022
Brugia malayi Patched related family protein 12 0.0019 0.002 0.0087
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0071 0.0213
Brugia malayi jmjC domain containing protein 0.0016 0.0014 0.0059
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0049 0.0048
Schistosoma mansoni hypothetical protein 0.0143 0.0304 0.0912
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0638 0.3361
Leishmania major UDP-galactopyranose mutase 0.0065 0.0125 0.0541
Entamoeba histolytica hypothetical protein 0.0025 0.0034 0.0176
Echinococcus multilocularis alkaline phosphatase 0.017 0.0366 0.047
Brugia malayi 6-phosphofructokinase 0.0113 0.0237 0.1035
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0111 0.0232 0.1014
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0014 0.0041
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0014 0.0041
Trichomonas vaginalis replication factor C large subunit, putative 0.0031 0.0047 0.0245
Brugia malayi steroid hormone receptor 0.0041 0.0071 0.031
Mycobacterium tuberculosis Conserved protein 0.0021 0.0023 0.0035
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0021 0.0091
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0123 0.0258 0.0252
Chlamydia trachomatis DNA ligase 0.0031 0.0047 0.0041
Entamoeba histolytica protein kinase, putative 0.017 0.0366 0.1929
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0065 0.0125 0.0124
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.0087 0.026
Trichomonas vaginalis BRCA1-associated protein, putative 0.0019 0.0019 0.0098
Toxoplasma gondii exonuclease III APE 0.002 0.0021 0.0021
Onchocerca volvulus 0.0034 0.0053 0.0446
Loa Loa (eye worm) patched family protein 0.0019 0.002 0.0087
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.031
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.017 0.0366 0.1098
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0051 0.0152
Brugia malayi kettin 0.0012 0.0004 0.0016
Onchocerca volvulus 0.0034 0.0053 0.0446
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0026 0.0079
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.0128 0.0559
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0 0.0001
Echinococcus multilocularis flap endonuclease GEN 1 0.0011 0.0001 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0058 0.0254
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0059
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0019 0.0019 0.014
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0266 0.0587 0.1761
Brugia malayi Pre-SET motif family protein 0.0033 0.0051 0.0221
Plasmodium falciparum glutathione reductase 0.0013 0.0006 0.0005
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0023 0.012
Echinococcus granulosus dna polymerase eta 0.0136 0.0289 0.0868
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0243 0.0534 0.1074
Brugia malayi hypothetical protein 0.0035 0.0057 0.0249
Echinococcus granulosus down syndrome cell adhesion 0.0012 0.0004 0.0011
Plasmodium falciparum thioredoxin reductase 0.0038 0.0063 0.0062
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0136 0.0288 0.1257
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0836 0.1897 1
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0087 0.0378
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Schistosoma mansoni hypothetical protein 0.0066 0.0128 0.0384
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0087 0.0456
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0014 0.0041
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Echinococcus granulosus titin 0.0016 0.0014 0.0041
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0021 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0292 0.0876
Loa Loa (eye worm) hypothetical protein 0.0044 0.0078 0.034
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0004 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0008 0.004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0058 0.0254
Onchocerca volvulus Histone deacetylase 10 homolog 0.0419 0.0938 0.8459
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0258 0.1129
Schistosoma mansoni titin 0.0012 0.0004 0.0011
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0071 0.031
Treponema pallidum P26 0.0014 0.0008 0.0096
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0125 0.0376
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0402 0.2114
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0019 0.0019 0.0101
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0623 0.1409 0.1409
Echinococcus multilocularis Niemann Pick C1 protein 0.0316 0.0702 0.0901
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.0128 0.0384
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0181 0.0784
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0026 0.0112
Trypanosoma brucei histone deacetylase 4 0.1006 0.2288 1
Loa Loa (eye worm) chloride channel 3 0.0021 0.0023 0.0102
Trichomonas vaginalis AGC family protein kinase 0.017 0.0366 0.1927
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Echinococcus granulosus histone deacetylase 8 0.0419 0.0938 0.2816
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0111 0.0232 0.1015
Loa Loa (eye worm) hypothetical protein 0.0436 0.0979 0.4281
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0031 0.0047 0.0248
Trypanosoma brucei histone deacetylase 2 0.0419 0.0938 0.4099
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0028 0.0122
Loa Loa (eye worm) hypothetical protein 0.0263 0.058 0.2536
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0012 0.0004 0.0011
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0116
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0036 0.0059 0.0107
Echinococcus multilocularis roundabout 2 0.0058 0.011 0.0141
Leishmania major 4-coumarate:coa ligase-like protein 0.0123 0.0258 0.1124
Schistosoma mansoni hypothetical protein 0.0086 0.0175 0.0524
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0021 0.0092
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.0023 0.0035
Onchocerca volvulus 0.0041 0.0071 0.0609
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0023 0.0123
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0232
Loa Loa (eye worm) fli-1 protein 0.024 0.0528 0.2309
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0021 0.0245
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0021 0.0062
Plasmodium falciparum glutathione reductase 0.0038 0.0063 0.0062
Schistosoma mansoni DNA ligase IV 0.0031 0.0047 0.0142
Echinococcus multilocularis conserved hypothetical protein 0.0015 0.0011 0.0014
Onchocerca volvulus 0.0019 0.002 0.0147
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0021 0.0062
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0065 0.0125 0.016
Brugia malayi hypothetical protein 0.0019 0.002 0.0087
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0094 0.041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0067 0.0201
Echinococcus multilocularis transfer RNA-Phe 0.0012 0.0004 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0237 0.1247
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0023 0.0102
Brugia malayi hypothetical protein 0.0031 0.0047 0.0207
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0036 0.0059 0.0059
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0279 0.0836
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0006 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0292 0.0876
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0122
Plasmodium falciparum flap endonuclease 1 0.0054 0.01 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0051 0.0152
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0071 0.0213
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0123 0.0259 0.0514
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0046 0.0045
Trypanosoma cruzi histone deacetylase, putative 0.1006 0.2288 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0028 0.0085
Loa Loa (eye worm) acetylcholinesterase 1 0.0198 0.0432 0.1889
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0022 0.0065
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0054 0.01 0.0432
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0001 0.0002
Schistosoma mansoni casein kinase II beta subunit 0.0037 0.0061 0.0183
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0059 0.0053
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0258 0.1129
Leishmania major chloride channel protein, putative 0.0021 0.0023 0.0097
Brugia malayi Disorganized muscle protein 1 0.0012 0.0004 0.0016
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0071 0.0213
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0059 0.0252
Trichomonas vaginalis exonuclease%2C+putative 0.0011 0.0001 0.0002
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0011 0.0001 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0352 0.1534
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Brugia malayi Nuclear hormone receptor E75 0.002 0.0021 0.0091
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0021 0.0023 0.0023
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0021 0.0023 0.0035
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0057 0.0172
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0019 0.0079
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0071 0.0213
Loa Loa (eye worm) IMP dehydrogenase 1 0.0021 0.0023 0.0102
Mycobacterium tuberculosis Conserved hypothetical protein 0.0065 0.0125 0.0242
Toxoplasma gondii chorismate synthase, putative 0.4361 1 1
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0237 0.0435
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0014 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0023 0.0028 0.0083
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0836 0.1897 1
Brugia malayi SWIRM domain containing protein 0.0065 0.0125 0.0546
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0241
Loa Loa (eye worm) acetyltransferase 0.0151 0.0324 0.1414
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0623 0.1409 0.1404
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0237 0.1244
Echinococcus granulosus nibrin 0.0031 0.0047 0.0142
Giardia lamblia Hypothetical protein 0.0022 0.0027 0.0137
Brugia malayi N-terminal motif family protein 0.0181 0.0391 0.1709
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0059 0.0257
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0022 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0068 0.0131 0.0575
Brugia malayi ImpB/MucB/SamB family protein 0.0136 0.0289 0.1264
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0023 0.0102
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0059 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0402 0.2114
Echinococcus granulosus histone deacetylase 7 0.1006 0.2288 0.6865
Mycobacterium ulcerans acetyl-CoA synthetase 0.0036 0.0059 0.0053
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0021 0.0027
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0032 0.0041
Toxoplasma gondii histone deacetylase HDAC2 0.0836 0.1897 0.1897
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0021 0.011
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0023 0.012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0122
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0237 0.1247
Echinococcus granulosus acetylcholinesterase 0.0198 0.0432 0.1297
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Echinococcus multilocularis lachesin 0.0023 0.0028 0.0036
Trypanosoma cruzi aurora B kinase, putative 0.017 0.0366 0.16
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0424 0.2235
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0114
Brugia malayi hypothetical protein 0.0031 0.0047 0.0207
Loa Loa (eye worm) glutaminase 0.0584 0.1318 0.5762
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.017 0.0366 0.047
Entamoeba histolytica protein kinase domain containing protein 0.0192 0.0418 0.2201
Brugia malayi Fli-1 protein 0.024 0.0528 0.2309
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0046 0.004
Leishmania major DNA polymerase kappa, putative 0.0123 0.0259 0.1126
Trichomonas vaginalis ran, putative 0.0023 0.0028 0.0145
Echinococcus multilocularis BRCA1 associated protein 0.0019 0.0019 0.0025
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0036 0.0059 0.0053
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0012 0.0004 0.0005
Brugia malayi nuclear hormone receptor 0.002 0.0021 0.0091
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0059 0.0257
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0103
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0023 0.0029
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0237 0.0304
Toxoplasma gondii glycogen synthase, putative 0.0014 0.0008 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0028 0.0122
Plasmodium falciparum protein kinase 5 0.0048 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.0044 0.0077 0.0335
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0047 0.0245
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0001 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0071 0.031
Trypanosoma brucei chrX additional, unordered contigs 0.0034 0.0054 0.0232
Plasmodium vivax importin-beta 2, putative 0.0031 0.0047 0.0047
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0023 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Onchocerca volvulus 0.0019 0.002 0.0147
Echinococcus granulosus AMPK beta subunit 0.0111 0.0232 0.0697
Echinococcus granulosus Immunoglobulin 0.0036 0.0058 0.0175
Plasmodium vivax patched family protein, putative 0.0019 0.002 0.002
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0014 0.0008 0.0008
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0316 0.0702 0.3701
Loa Loa (eye worm) hypothetical protein 0.0188 0.0408 0.1782
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0051 0.0152
Echinococcus multilocularis Immunoglobulin 0.0036 0.0058 0.0075
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0028 0.0122
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0071 0.031
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0299 0.0564
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0059 0.0257
Echinococcus granulosus histone deacetylase 3 0.0836 0.1897 0.5692
Echinococcus multilocularis neuroligin 0.0034 0.0053 0.0068
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0034 0.0053 0.0096
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Trichomonas vaginalis histone deacetylase, putative 0.0836 0.1897 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0114
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.0047 0.0245
Plasmodium vivax histone deacetylase, putative 0.0419 0.0938 0.0938
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0071 0.0213
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0116
Schistosoma mansoni cellular tumor antigen P53 0.0101 0.0208 0.0625
Brugia malayi 6-phosphofructokinase 0.0113 0.0237 0.1034
Schistosoma mansoni histone deacetylase 4 5 0.1006 0.2288 0.6865
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0088 0.0263
Onchocerca volvulus 0.0019 0.002 0.0147
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) loechrig isoform VII 0.0229 0.0503 0.2201
Echinococcus granulosus GA binding protein alpha chain 0.0079 0.0158 0.0474
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.001
Brugia malayi Ets-domain containing protein 0.0011 0.0002 0.001
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0087 0.0378
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0232
Brugia malayi Carboxylesterase family protein 0.0034 0.0053 0.0232
Loa Loa (eye worm) TK protein kinase 0.0017 0.0014 0.0063
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0087 0.0379
Chlamydia trachomatis CBS domain-containing protein 0.0021 0.0023 0.0017
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0006 0.0008
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0192 0.0418 0.1822
Echinococcus granulosus histone deacetylase 1 0.0836 0.1897 0.5692
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0014 0.0059
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0137
Mycobacterium ulcerans hypothetical protein 0.0123 0.0258 0.0252
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.0094 0.0409
Brugia malayi protein C24B5.3 0.0019 0.002 0.0087
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0046 0.0046
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0086 0.0175 0.0524
Brugia malayi Latrophilin receptor protein 2 0.0066 0.0128 0.0559
Schistosoma mansoni amine oxidase 0.0065 0.0125 0.0375
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0111
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0002 0.001
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0049 0.0212
Brugia malayi ancient conserved domain protein 4 0.0021 0.0023 0.0102
Schistosoma mansoni topbp1 0.0031 0.0047 0.0142
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0279 0.0836
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.0047 0.0245
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0023 0.0098
Toxoplasma gondii ck2 beta subunit 0.0037 0.0061 0.0061
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0021 0.0023 0.0205
Giardia lamblia Aurora kinase 0.017 0.0366 0.1927
Loa Loa (eye worm) hypothetical protein 0.0092 0.0187 0.0817
Schistosoma mansoni cell adhesion molecule 0.0023 0.0028 0.0083
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0034 0.0053 0.0159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0638 0.3361
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0067 0.0293
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0027 0.0026
Echinococcus granulosus serine:threonine protein kinase 12 B 0.017 0.0366 0.1099
Schistosoma mansoni vesicular amine transporter 0.004 0.0067 0.0202
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0006 0.0006
Echinococcus granulosus titin 0.0012 0.0004 0.0011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0014 0.0063
Toxoplasma gondii propionate-CoA ligase 0.0036 0.0059 0.0059
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Echinococcus granulosus tyrosine protein kinase otk 0.0023 0.0028 0.0083
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Schistosoma mansoni exonuclease 0.0011 0.0001 0.0004
Plasmodium vivax acetyl-CoA synthetase, putative 0.0036 0.0059 0.0059
Echinococcus granulosus titin 0.0012 0.0004 0.0011
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0059 0.0107
Plasmodium falciparum serine/threonine protein kinase KIN 0.0049 0.0088 0.0086
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0111 0.0232 0.1015
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0047 0.0245
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0021 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0071 0.031
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0071 0.031
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0321 0.0713 0.2141
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0054 0.01 0.0436
Toxoplasma gondii aurora kinase 0.017 0.0366 0.0366
Entamoeba histolytica protein kinase, putative 0.017 0.0366 0.1929
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0352 0.1534
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0078 0.0408
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0023 0.0023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Entamoeba histolytica protein kinase, putative 0.0051 0.0094 0.0493
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0013 0.0007 0.0001
Toxoplasma gondii patched family protein 0.0019 0.002 0.002
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0059 0.0257
Loa Loa (eye worm) apoptosis regulator protein 0.0086 0.0175 0.0763
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0071 0.031
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0067 0.0201
Trypanosoma cruzi DNA polymerase kappa, putative 0.0164 0.0352 0.1538
Schistosoma mansoni hypothetical protein 0.0175 0.0379 0.1138
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0014 0.0063
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0117 0.015
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0305 0.1327
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0011
Plasmodium falciparum NIMA related kinase 2 0.0022 0.0026 0.0025
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0021 0.0107
Echinococcus granulosus protein C ets 2 0.0011 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0016
Entamoeba histolytica hypothetical protein 0.0035 0.0057 0.0302
Brugia malayi Fibronectin type III domain containing protein 0.0036 0.0058 0.0254
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0026
Brugia malayi Pax transcription activation domain interacting protein 0.0031 0.0047 0.0207
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0302 0.067 0.2927
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Schistosoma mansoni titin 0.0012 0.0004 0.0011
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0061 0.0265
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0023 0.012
Trichomonas vaginalis helicase, putative 0.0014 0.0008 0.004
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0192 0.0418 0.1825
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0026 0.0133
Trypanosoma brucei DNA polymerase IV, putative 0.015 0.0321 0.14
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0019 0.0018
Mycobacterium ulcerans monoamine oxidase 0.0065 0.0125 0.0119
Schistosoma mansoni DNA helicase recq5 0.0021 0.0023 0.007
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0023 0.0103
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0006 0.0022
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0002 0.0007
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0036 0.0059 0.0177
Trichomonas vaginalis AGC family protein kinase 0.017 0.0366 0.1927
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.004
Leishmania major trypanothione reductase 0.0038 0.0063 0.027
Echinococcus granulosus roundabout 2 0.0023 0.0028 0.0083
Echinococcus granulosus bloom syndrome protein 0.0021 0.0023 0.007
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0078 0.0078
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0381 0.0851 0.0846
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0251 0.0552 0.1657
Loa Loa (eye worm) hypothetical protein 0.0629 0.1421 0.6212
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0011
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0021 0.0091
Loa Loa (eye worm) animal heme peroxidase 0.0012 0.0004 0.0016
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0027 0.0038 0.0165
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0036 0.0059 0.0053
Loa Loa (eye worm) oxidoreductase 0.0036 0.0059 0.0257
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0023 0.0103
Loa Loa (eye worm) RNA binding protein 0.0132 0.0279 0.1218
Echinococcus multilocularis dna polymerase eta 0.0136 0.0289 0.0371
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0021 0.0023 0.0035
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.005 0.022
Toxoplasma gondii histone lysine methyltransferase SET1 0.0123 0.0258 0.0258
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0638 0.3361
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0021 0.0062
Schistosoma mansoni hypothetical protein 0.0886 0.2011 0.6037
Echinococcus granulosus Niemann Pick C1 protein 0.0316 0.0702 0.2107
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0174 0.0343
Leishmania major protein kinase, putative 0.0022 0.0026 0.0108
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0059 0.0252
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0115 0.0503
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0241
Trichomonas vaginalis histone deacetylase, putative 0.0836 0.1897 1
Brugia malayi amine oxidase, flavin-containing family protein 0.0065 0.0125 0.0546
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0032 0.0097
Brugia malayi hypothetical protein 0.0436 0.0979 0.4281
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0071 0.031
Echinococcus granulosus exonuclease 1 0.0011 0.0001 0.0004
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0071 0.0609
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0087 0.0378
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0088 0.0263
Brugia malayi Patched family protein 0.0019 0.002 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.004
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0054 0.0232
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0071 0.0091
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0091
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0012 0.0004 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0047 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0366 0.1099
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0051 0.0065
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0054 0.0232
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0006 0.0026
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0527 0.1187 0.5189
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0022 0.0097
Schistosoma mansoni titin 0.0016 0.0014 0.0041
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0063 0.0275
Echinococcus granulosus dnaJ subfamily B 0.0886 0.2011 0.6037
Brugia malayi jmjC domain containing protein 0.0065 0.0125 0.0547
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0237 0.1034
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317
Brugia malayi Carboxylesterase family protein 0.0034 0.0053 0.0232
Treponema pallidum hemolysin (tlyC) 0.0021 0.0023 0.0273
Loa Loa (eye worm) histone methyltransferase 0.002 0.0023 0.01
Loa Loa (eye worm) hypothetical protein 0.027 0.0597 0.2609
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.031
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0012 0.0004 0.0016
Brugia malayi RNA, U transporter 1 0.0088 0.0178 0.0778
Schistosoma mansoni DNA helicase recq1 0.0021 0.0023 0.007
Plasmodium vivax replication factor C subunit 1, putative 0.0031 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Schistosoma mansoni coup transcription factor 0.0041 0.0071 0.0213
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0078 0.0078
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0021 0.0023 0.0205
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0022 0.0028
Echinococcus multilocularis expressed protein 0.0032 0.005 0.0065
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0263 0.058 0.1741
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0241
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0028 0.0122
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0078 0.0078
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0164 0.0352 0.1852
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0021 0.0063
Loa Loa (eye worm) patched family protein 0.0019 0.002 0.0087
Loa Loa (eye worm) histone deacetylase 11 0.0419 0.0938 0.4102
Echinococcus multilocularis roundabout 2 0.0023 0.0028 0.0036
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0036 0.0059 0.0053
Mycobacterium ulcerans hypothetical protein 0.0034 0.0054 0.0048
Schistosoma mansoni ets-related 0.0011 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0071 0.031
Trichomonas vaginalis AGC family protein kinase 0.017 0.0366 0.1927
Schistosoma mansoni histone deacetylase hda2 0.1024 0.2331 0.6995
Brugia malayi jmjC domain containing protein 0.0016 0.0014 0.0059
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0019 0.0019 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0522 0.1566
Onchocerca volvulus 0.0034 0.0053 0.0446
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0023 0.0028 0.0036
Loa Loa (eye worm) hypothetical protein 0.0044 0.0078 0.034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0102
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0002 0.0007
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0237 0.103
Brugia malayi ancient conserved domain protein 2 0.0021 0.0023 0.0102
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Onchocerca volvulus 0.0034 0.0053 0.0446
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0019 0.0019
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0049 0.0208
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0111
Trypanosoma brucei GMP reductase 0.0021 0.0023 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0088 0.0458
Schistosoma mansoni protein kinase subunit beta 0.0111 0.0232 0.0697
Echinococcus multilocularis peroxidasin 0.0023 0.0028 0.0036
Trypanosoma brucei DNA polymerase IV, putative 0.0164 0.0352 0.1534
Loa Loa (eye worm) histone deacetylase 0.1006 0.2288 1
Loa Loa (eye worm) flap endonuclease-1 0.0054 0.01 0.0437
Trypanosoma brucei SNF1-related protein kinases, putative 0.0049 0.0088 0.0378
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0034 0.0146
Trichomonas vaginalis histone deacetylase, putative 0.0836 0.1897 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0207
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0116
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0021 0.0091
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0014 0.0042
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0232
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0026 0.0079
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0014 0.0041
Echinococcus granulosus neuroligin 0.0034 0.0053 0.0159
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0027 0.0034
Mycobacterium ulcerans cystathionine beta-synthase 0.0021 0.0023 0.0017
Schistosoma mansoni cell adhesion molecule 0.0012 0.0004 0.0011
Trypanosoma cruzi DNA polymerase kappa, putative 0.0164 0.0352 0.1538
Schistosoma mansoni cpg binding protein 0.0066 0.0127 0.0381
Onchocerca volvulus 0.0021 0.0023 0.0178
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0004 0.0016
Loa Loa (eye worm) glutathione reductase 0.0038 0.0063 0.0275
Toxoplasma gondii thioredoxin reductase 0.0038 0.0063 0.0063
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0111 0.0232 0.1014
Mycobacterium ulcerans hypothetical protein 0.0021 0.0023 0.0017
Leishmania major CBS domain protein, conserved 0.0021 0.0023 0.0097
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0087
Loa Loa (eye worm) patched family protein 0.0019 0.002 0.0087
Entamoeba histolytica serine/threonine protein kinase, putative 0.0022 0.0026 0.0136
Echinococcus granulosus tumor protein p63 0.069 0.1562 0.4688
Schistosoma mansoni cpg binding protein 0.0066 0.0127 0.0381
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0026 0.0079
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0061 0.0317

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) nM Agonist activity by [Ca2+] uptake in CHO cells expressing rat TRPV1 at 10-30 uM; NE = Not effective ChEMBL. 16005215
EC50 (functional) 0 nM Agonist activity by [Ca2+] uptake in CHO cells expressing rat TRPV1 at 10-30 uM; NE = Not effective ChEMBL. 16005215
Ki (functional) = 45.5 nM Antagonist activity for rat TRPV1 expressed in CHO cells ChEMBL. 16005215
Ki (functional) = 45.5 nM Antagonist activity for rat TRPV1 expressed in CHO cells ChEMBL. 16005215
Ki (binding) = 144 nM In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTX ChEMBL. 16005215
Ki (binding) = 144 nM In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTX ChEMBL. 16005215

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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