Detailed information for compound 331920

Basic information

Technical information
  • TDR Targets ID: 331920
  • Name: (6aR,10aR)-3-(1-adamantyl)-6,6,9-trimethyl-6a ,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
  • MW: 378.547 | Formula: C26H34O2
  • H donors: 1 H acceptors: 1 LogP: 6.71 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(C2)CC(C1)C3
  • InChi: 1S/C26H34O2/c1-15-4-5-21-20(6-15)24-22(27)10-19(11-23(24)28-25(21,2)3)26-12-16-7-17(13-26)9-18(8-16)14-26/h4,10-11,16-18,20-21,27H,5-9,12-14H2,1-3H3/t16?,17?,18?,20-,21-,26?/m1/s1
  • InChiKey: RPBMPWGKZFLMFN-OKFSJJLXSA-N  

Network

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Synonyms

  • (6aR,10aR)-3-(1-adamantyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c][1]benzopyran-1-ol

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cannabinoid receptor 2 (macrophage) Starlite/ChEMBL References
Mus musculus cannabinoid receptor 2 (macrophage) Starlite/ChEMBL References
Homo sapiens cannabinoid receptor 1 (brain) Starlite/ChEMBL References
Rattus norvegicus Cannabinoid CB1 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0093 0.0102 0.0102
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0028 0.0221
Echinococcus multilocularis Mastin 0.0024 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0083
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0055 0.005 0.0344
Loa Loa (eye worm) patched family protein 0.0019 0.0002 0.0016
Leishmania major trypanothione reductase 0.0038 0.0028 0.0179
Trypanosoma cruzi hypothetical protein 0.0091 0.0099 0.0688
Loa Loa (eye worm) hypothetical protein 0.0164 0.0196 0.1384
Echinococcus multilocularis expressed conserved protein 0.0292 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0038 0.0028 0.0097
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0022 0.0006 0.0016
Mycobacterium ulcerans chorismate synthase 0.5001 0.6673 1
Schistosoma mansoni ran 0.0065 0.0064 0.022
Echinococcus multilocularis importin subunit beta 1 0.0088 0.0095 0.0095
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.002 0.0027
Brugia malayi Melatonin receptor type 1A 0.0093 0.0102 0.0719
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0038 0.0028 0.0221
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0938 0.1233 0.8709
Wolbachia endosymbiont of Brugia malayi excinuclease ABC subunit C 0.0021 0.0005 0.0006
Echinococcus multilocularis roundabout 2 0.0062 0.006 0.006
Echinococcus granulosus alpha 1A adrenergic receptor 0.0093 0.0102 0.0352
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0026 0.0011 0.0073
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0072 0.0249
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0064 0.0063 0.0175
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0136 0.117
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0199 0.1723
Schistosoma mansoni microtubule-associated protein tau 0.2178 0.2893 1
Mycobacterium ulcerans hypothetical protein 0.0323 0.0409 0.0604
Loa Loa (eye worm) Csnk2b protein 0.0037 0.0027 0.019
Loa Loa (eye worm) hypothetical protein 0.0156 0.0186 0.1314
Brugia malayi latrophilin 2 splice variant baaae 0.0249 0.031 0.2189
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0072 0.0509
Schistosoma mansoni histone deacetylase hda2 0.0442 0.0569 0.1968
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.087 0.1142 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0127 0.0148 0.0434
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0198 0.0242 0.1694
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.0107 0.0309
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0077 0.008 0.0673
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0136 0.0944
Trypanosoma brucei unspecified product 0.0078 0.0082 0.0558
Echinococcus granulosus dual specificity 0.0198 0.0242 0.0837
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0136 0.2287
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0093 0.0102 0.0352
Giardia lamblia Kinase, CAMK CAMKL 0.0051 0.0045 0.0344
Brugia malayi hypothetical protein 0.0033 0.0021 0.015
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0063 0.0061 0.0429
Echinococcus granulosus neuropeptides capa receptor 0.0093 0.0102 0.0352
Onchocerca volvulus 0.0054 0.0049 0.073
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Echinococcus multilocularis para nitrobenzyl esterase 0.0091 0.0099 0.0099
Echinococcus multilocularis neuropeptide Y receptor 0.0093 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Leishmania major GTP-binding protein, putative 0.0065 0.0064 0.043
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0249 0.031 0.219
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0063 0.0434
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0012 0.0075
Onchocerca volvulus Protein patched homolog 0.0019 0.0002 0.0034
Onchocerca volvulus 0.0093 0.0102 0.1523
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0026 0.0011 0.0079
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0275 0.0346 0.1194
Leishmania major DNA polymerase kappa, putative 0.0127 0.0148 0.1025
Trichomonas vaginalis glutaminase, putative 0.0567 0.0736 0.6432
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0117 0.0133 0.0941
Brugia malayi nuclear receptor NHR-88 0.0063 0.0061 0.0429
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0054 0.0049 0.0169
Loa Loa (eye worm) trypsin family protein 0.0024 0.0009 0.0064
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0136 0.117
Toxoplasma gondii thioredoxin reductase 0.0038 0.0028 0.0039
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0022 0.0006 0.0006
Schistosoma mansoni topbp1 0.0067 0.0066 0.023
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0016 0.0057
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0056 0.0076
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.024 0.0299 0.1033
Loa Loa (eye worm) hypothetical protein 0.0194 0.0236 0.1668
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0136 0.117
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0215 0.0743
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.023 0.0285 0.2015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.015
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0031
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0067 0.0066 0.0558
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0093 0.0102 0.0102
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0085
Echinococcus multilocularis neuropeptides capa receptor 0.0093 0.0102 0.0102
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.029 0.0365 0.2563
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.02
Loa Loa (eye worm) hypothetical protein 0.0049 0.0043 0.0304
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0199 0.1723
Trypanosoma brucei DNA polymerase IV, putative 0.017 0.0205 0.1428
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Echinococcus granulosus neuroligin 0.0091 0.0099 0.0343
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0136 0.0195
Trichomonas vaginalis antibiotic synthetase, putative 0.0064 0.0063 0.0526
Giardia lamblia Replication factor C, subunit 1 0.0067 0.0066 0.0532
Schistosoma mansoni hypothetical protein 0.0029 0.0015 0.0053
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.002 0.0027
Plasmodium vivax SET domain protein, putative 0.0035 0.0024 0.0033
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0093 0.0102 0.0719
Entamoeba histolytica protein kinase, putative 0.0198 0.0242 0.21
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0104 0.0116 0.0171
Echinococcus multilocularis G-protein coupled receptor, putative 0.0093 0.0102 0.0102
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0102 0.0102
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0011 0.0079
Plasmodium vivax flap endonuclease 1, putative 0.0055 0.005 0.0072
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0113 0.0129 0.0445
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0045 0.0156
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0093 0.0102 0.0352
Schistosoma mansoni hypothetical protein 0.0021 0.0004 0.0016
Schistosoma mansoni neuroligin 3 (S09 family) 0.0091 0.0099 0.0343
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0006 0.0043
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0311 0.0393 0.3427
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Loa Loa (eye worm) steroid hormone receptor 0.0063 0.0061 0.0429
Loa Loa (eye worm) hypothetical protein 0.0541 0.0701 0.4951
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.2466 0.3279 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0077 0.008 0.0275
Plasmodium vivax replication factor C subunit 1, putative 0.0067 0.0066 0.0096
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0093 0.0102 0.0352
Trypanosoma cruzi histone deacetylase, putative 0.0442 0.0569 0.4016
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0098 0.0108 0.0373
Echinococcus granulosus sentrin specific protease 7 0.0171 0.0206 0.0712
Toxoplasma gondii histone deacetylase HDAC3 0.087 0.1142 0.1709
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Trypanosoma brucei DNA polymerase IV, putative 0.0156 0.0186 0.1295
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0055 0.005 0.0334
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0021 0.0005 0.0027
Echinococcus multilocularis g protein coupled receptor 0.0093 0.0102 0.0102
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0218 0.0269 0.0395
Echinococcus granulosus g protein coupled receptor 0.0093 0.0102 0.0352
Echinococcus granulosus H:Cl exchange transporter 4 0.0022 0.0006 0.0021
Schistosoma mansoni nephrin 0.0024 0.0009 0.003
Trypanosoma cruzi DNA polymerase eta, putative 0.0063 0.0061 0.0425
Echinococcus granulosus histone deacetylase 6 0.1094 0.1441 0.4983
Schistosoma mansoni cell adhesion molecule 0.0024 0.0009 0.003
Toxoplasma gondii CBS domain-containing protein 0.0022 0.0006 0.0006
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0006 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0061
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0011 0.0059
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0006 0.0043
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0047 0.0067
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0006 0.0027
Schistosoma mansoni neuroglian 0.0024 0.0009 0.003
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0026 0.0011 0.0039
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0026 0.0011 0.0013
Schistosoma mansoni casein kinase II beta subunit 0.0037 0.0027 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0023 0.0007 0.004
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0016 0.0057
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0068 0.0067 0.0467
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0083
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0064 0.0063 0.0085
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0006 0.0006
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.002 0.015
Echinococcus multilocularis neuropeptide receptor 0.0093 0.0102 0.0102
Echinococcus granulosus neuropeptide receptor A26 0.0093 0.0102 0.0352
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0136 0.0962
Schistosoma mansoni chromosome transmission fidelity factor 0.0067 0.0066 0.023
Echinococcus multilocularis protein dispatched 1 0.0152 0.0181 0.0181
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0091 0.0099 0.0287
Echinococcus granulosus sex peptide receptor 0.0093 0.0102 0.0352
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Onchocerca volvulus 0.0024 0.0009 0.0136
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0012 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0149 0.0514
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0071 0.0072 0.061
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0093 0.0102 0.0719
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0012 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0102 0.0102
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0117 0.0133 0.0932
Echinococcus multilocularis histone deacetylase 6 0.1075 0.1416 0.1416
Echinococcus multilocularis allatostatin A receptor 0.0093 0.0102 0.0102
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0249 0.031 0.1072
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0105 0.0117 0.0821
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0093 0.0102 0.0352
Trichomonas vaginalis ran, putative 0.0065 0.0064 0.0533
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0064 0.0063 0.0085
Trichomonas vaginalis AGC family protein kinase 0.0178 0.0215 0.1861
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0218 0.0269 0.0395
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0109
Schistosoma mansoni ap endonuclease 0.004 0.003 0.0103
Trypanosoma cruzi cdc2-related kinase 3 0.005 0.0045 0.0305
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0094 0.0269
Trichomonas vaginalis CAMK family protein kinase 0.0023 0.0007 0.004
Schistosoma mansoni amine GPCR 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0006 0.0043
Trypanosoma cruzi chloride channel protein, putative 0.0022 0.0006 0.0032
Giardia lamblia DNA damage repair protein 0.0035 0.0024 0.016
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0028 0.0221
Brugia malayi Dopamine receptor 0.0093 0.0102 0.0719
Echinococcus multilocularis histone deacetylase 3 0.087 0.1142 0.1142
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0101 0.0691
Brugia malayi Ets-domain containing protein 0.0021 0.0004 0.0032
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0091 0.0099 0.0099
Brugia malayi hypothetical protein 0.0132 0.0153 0.1084
Loa Loa (eye worm) hypothetical protein 0.0152 0.0181 0.1279
Trypanosoma brucei histone deacetylase 4 0.1075 0.1416 1
Echinococcus granulosus Niemann Pick C1 protein 0.0445 0.0572 0.1978
Plasmodium vivax sentrin-specific protease 2, putative 0.0038 0.0028 0.0039
Entamoeba histolytica acyl-CoA synthetase, putative 0.0218 0.0269 0.2338
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0063 0.0061 0.0089
Mycobacterium ulcerans acyl-CoA synthetase 0.0218 0.0269 0.0395
Brugia malayi Trypsin family protein 0.0024 0.0009 0.0064
Brugia malayi hypothetical protein 0.0046 0.0039 0.0276
Schistosoma mansoni cell adhesion molecule 0.0024 0.0009 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Onchocerca volvulus 0.0029 0.0016 0.0247
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0016 0.0116
Brugia malayi BRCA1-associated protein 2 containing protein 0.0019 0.0003 0.002
Echinococcus multilocularis lysine specific demethylase 5A 0.0064 0.0063 0.0063
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0063 0.0444
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0063 0.0061 0.0061
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0016 0.0116
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0021 0.0005 0.0017
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Brugia malayi Protein kinase domain containing protein 0.0198 0.0242 0.1711
Echinococcus multilocularis alkaline phosphatase 0.0178 0.0215 0.0215
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0938 0.1233 0.4262
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0034 0.0275
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0064
Loa Loa (eye worm) hypothetical protein 0.0104 0.0116 0.082
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0199 0.1723
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.015
Echinococcus multilocularis muscleblind protein 1 0.0623 0.0811 0.0811
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0074 0.0074
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0065 0.0064 0.044
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.0107 0.0308
Echinococcus granulosus twitchin 0.0056 0.0051 0.0178
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0043
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0009 0.003
Plasmodium falciparum NIMA related kinase 2 0.0023 0.0007 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0218 0.0269 0.1886
Echinococcus granulosus dnaJ subfamily B 0.0845 0.1108 0.383
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0077 0.008 0.0275
Trypanosoma cruzi importin beta-1 subunit, putative 0.0071 0.0072 0.0502
Leishmania major 4-coumarate:coa ligase-like protein 0.0218 0.0269 0.1886
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0024 0.0161
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0199 0.1723
Schistosoma mansoni alkaline phosphatase 0.0178 0.0215 0.0744
Leishmania major histone deacetylase, putative 0.1075 0.1416 1
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0171 0.0206 0.0712
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Plasmodium falciparum importin beta, putative 0.0088 0.0095 0.0139
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0026 0.0011 0.0079
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0063 0.0061 0.021
Loa Loa (eye worm) hypothetical protein 0.0163 0.0195 0.1381
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0063 0.0175
Plasmodium vivax DNA repair protein REV1, putative 0.0035 0.0024 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0083
Echinococcus multilocularis FTZ F1 alpha 0.0063 0.0061 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0045 0.0156
Onchocerca volvulus Bile acid receptor homolog 0.0063 0.0061 0.0908
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0218 0.0269 0.0805
Echinococcus granulosus fmrfamide receptor 0.0093 0.0102 0.0352
Schistosoma mansoni amine GPCR 0.0093 0.0102 0.0352
Brugia malayi hypothetical protein 0.0019 0.0002 0.0016
Brugia malayi SWIRM domain containing protein 0.0104 0.0116 0.082
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0068 0.0067 0.0457
Trypanosoma brucei metacaspase MCA3 0.0026 0.0012 0.0065
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0023 0.0007 0.0032
Schistosoma mansoni growth hormone secretagogue receptor 0.0093 0.0102 0.0352
Mycobacterium ulcerans acetyl-CoA synthetase 0.0064 0.0063 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0045 0.0156
Brugia malayi Carboxylesterase family protein 0.0541 0.0701 0.4951
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Echinococcus granulosus AMPK beta subunit 0.0117 0.0133 0.0461
Echinococcus granulosus neuropeptides capa receptor 0.0093 0.0102 0.0352
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0091 0.0099 0.0697
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.015
Schistosoma mansoni hypothetical protein 0.0021 0.0004 0.0016
Echinococcus granulosus snurportin 1 0.0938 0.1233 0.4262
Schistosoma mansoni coup transcription factor 0.0063 0.0061 0.021
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0019 0.0003 0.002
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0066 0.0558
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0064 0.0063 0.0085
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0198
Brugia malayi transcription factor E74 isoform 0.0021 0.0004 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0061 0.0429
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0091 0.0098 0.034
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0115 0.0131 0.0453
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0038 0.0028 0.0039
Loa Loa (eye worm) hypothetical protein 0.0067 0.0066 0.0469
Trypanosoma brucei protein kinase, putative 0.0054 0.0049 0.0325
Trypanosoma brucei DNA polymerase IV, putative 0.017 0.0205 0.1428
Brugia malayi larval opioid receptor 0.0093 0.0102 0.0719
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.003 0.0496
Brugia malayi Pre-SET motif family protein 0.023 0.0285 0.2015
Echinococcus granulosus para nitrobenzyl esterase 0.0091 0.0099 0.0343
Plasmodium vivax acyl-CoA synthetase, putative 0.0163 0.0195 0.029
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0117 0.0133 0.0923
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0042
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0037 0.0027 0.0037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0012 0.0083
Entamoeba histolytica protein kinase domain containing protein 0.0054 0.0049 0.0403
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Trypanosoma brucei histone deacetylase 3 0.1075 0.1416 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0077 0.008 0.0673
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0094 0.0269
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Brugia malayi Serotonin receptor 0.0093 0.0102 0.0719
Echinococcus multilocularis dro:myosuppressin receptor 0.0093 0.0102 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0457 0.0589 0.4161
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Echinococcus multilocularis snurportin 1 0.0938 0.1233 0.1233
Echinococcus multilocularis Niemann Pick C1 protein 0.0445 0.0572 0.0572
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0063 0.0061 0.021
Onchocerca volvulus 0.0093 0.0102 0.1523
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0022 0.0006 0.0016
Echinococcus granulosus conserved hypothetical protein 0.0029 0.0015 0.0053
Echinococcus granulosus neuropeptide s receptor 0.0093 0.0102 0.0352
Brugia malayi Flap endonuclease-1 0.0055 0.005 0.0354
Trypanosoma brucei DNA polymerase kappa, putative 0.017 0.0205 0.1428
Echinococcus granulosus neuropeptide receptor 0.0093 0.0102 0.0352
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0038 0.0028 0.0188
Loa Loa (eye worm) hypothetical protein 0.0051 0.0045 0.0319
Plasmodium vivax sentrin-specific protease 1, putative 0.0038 0.0028 0.0039
Leishmania major hypothetical protein, conserved 0.0052 0.0047 0.031
Echinococcus multilocularis sentrin specific protease 7 0.0171 0.0206 0.0206
Leishmania major DNA polymerase eta, putative 0.0063 0.0061 0.0414
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0154 0.0184 0.0544
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0198
Echinococcus granulosus Immunoglobulin 0.0038 0.0028 0.0098
Loa Loa (eye worm) RNA binding protein 0.0128 0.0149 0.1051
Onchocerca volvulus 0.0091 0.0099 0.1486
Toxoplasma gondii NEK kinase 0.0023 0.0007 0.0008
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0028 0.0221
Toxoplasma gondii CBS domain-containing protein 0.0022 0.0006 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.002 0.015
Brugia malayi neuropeptide F receptor 0.0093 0.0102 0.0719
Echinococcus granulosus hemicentin 1 0.0024 0.0009 0.003
Echinococcus multilocularis acetylcholinesterase 0.0541 0.0701 0.0701
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.002 0.0124
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Onchocerca volvulus 0.0093 0.0102 0.1523
Schistosoma mansoni hypothetical protein 0.0024 0.0009 0.0031
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0026 0.0011 0.0039
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0051 0.0045 0.0299
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0016 0.0057
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0063 0.0085
Brugia malayi Carboxylesterase family protein 0.0091 0.0099 0.0702
Echinococcus multilocularis roundabout 2 0.0024 0.0009 0.0009
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.029 0.0365 0.2571
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0022 0.0006 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0063 0.0444
Schistosoma mansoni titin 0.0024 0.0009 0.003
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Echinococcus granulosus dna polymerase kappa 0.017 0.0205 0.0707
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0034 0.0048
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0026 0.0012 0.0085
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.002 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.008
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0026 0.0011 0.0013
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0253 0.0316 0.223
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0163 0.0195 0.0284
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0063 0.0061 0.0429
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0202 0.0248 0.175
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0026 0.0011 0.0013
Entamoeba histolytica hypothetical protein 0.0198 0.0242 0.21
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0026 0.0011 0.0046
Leishmania major guanosine monophosphate reductase 0.0022 0.0006 0.0022
Schistosoma mansoni DNA polymerase IV / kappa 0.0035 0.0024 0.0083
Echinococcus multilocularis expressed conserved protein 0.0133 0.0155 0.0155
Toxoplasma gondii histone lysine methyltransferase SET1 0.0226 0.0279 0.0416
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1372 0.1813 0.5523
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0061
Echinococcus multilocularis protein patched 0.0133 0.0156 0.0156
Schistosoma mansoni cell adhesion molecule 0.0024 0.0009 0.003
Entamoeba histolytica acyl-coA synthetase, putative 0.0218 0.0269 0.2338
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0016 0.0057
Onchocerca volvulus 0.0093 0.0102 0.1523
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0054 0.0049 0.0335
Echinococcus granulosus roundabout 2 0.0062 0.006 0.0207
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0061
Leishmania major hypothetical protein, conserved 0.0022 0.0006 0.0022
Onchocerca volvulus 0.0091 0.0099 0.1486
Echinococcus multilocularis aurora kinase A 0.0178 0.0215 0.0215
Echinococcus granulosus defective proboscis extension response 0.0038 0.0028 0.0098
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0091 0.0099 0.0846
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0063 0.0061 0.021
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0253 0.0316 0.223
Schistosoma mansoni neuropeptide receptor 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0064
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0093 0.0102 0.0102
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0211 0.1828
Schistosoma mansoni nuclear receptor 0.0029 0.0016 0.0057
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0022 0.0006 0.0032
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0051 0.0045 0.0299
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0024 0.0083
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0061
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.003 0.0103
Echinococcus multilocularis neuropeptide receptor 0.0093 0.0102 0.0102
Trypanosoma cruzi metacaspase, putative 0.0026 0.0012 0.0075
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0063 0.0175
Trichomonas vaginalis ap endonuclease, putative 0.004 0.003 0.0237
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0049 0.0043 0.0061
Schistosoma mansoni hypothetical protein 0.0091 0.0098 0.034
Giardia lamblia Flap structure-specific endonuclease 0.0055 0.005 0.0388
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0061
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.003 0.0211
Plasmodium vivax histone deacetylase 1, putative 0.087 0.1142 0.1709
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0077 0.008 0.0543
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0003 0.0001
Echinococcus multilocularis neuroglian 0.0051 0.0045 0.0045
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0104 0.0116 0.0337
Onchocerca volvulus 0.0093 0.0102 0.1523
Loa Loa (eye worm) TYRA-2 protein 0.0093 0.0102 0.0719
Onchocerca volvulus 0.0093 0.0102 0.1523
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0316 0.2744
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0018 0.0001 0.0002
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0612 0.0797 0.562
Loa Loa (eye worm) hypothetical protein 0.0091 0.0099 0.0702
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0102 0.0352
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0065 0.0064 0.0449
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0016 0.0016
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0024 0.0009 0.0061
Loa Loa (eye worm) melatonin receptor type 1A 0.0093 0.0102 0.0719
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0083
Echinococcus multilocularis serotonin receptor 0.0093 0.0102 0.0102
Onchocerca volvulus 0.0093 0.0102 0.1523
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0063 0.0061 0.0429
Schistosoma mansoni caspase-3 (C14 family) 0.0098 0.0108 0.0373
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0038 0.0028 0.0039
Onchocerca volvulus 0.0093 0.0102 0.1523
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0136 0.0471
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0031
Onchocerca volvulus 0.0038 0.0028 0.042
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0006 0.0006
Echinococcus multilocularis neuropeptide Y receptor 0.0093 0.0102 0.0102
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0064 0.0063 0.0526
Echinococcus multilocularis expressed protein 0.0069 0.007 0.007
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.082 0.1075 0.3267
Brugia malayi tailless protein 0.0029 0.0016 0.0116
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Brugia malayi ORL1-like opioid receptor 0.0093 0.0102 0.0719
Toxoplasma gondii IMP dehydrogenas 0.0022 0.0006 0.0006
Brugia malayi serine/threonine-protein kinase 6 0.0178 0.0215 0.1519
Brugia malayi nuclear receptor RXR 0.0033 0.0021 0.015
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0163 0.0195 0.0284
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0093 0.0102 0.0102
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0003 0.001
Echinococcus multilocularis ets variant gene 4 0.0021 0.0004 0.0004
Echinococcus granulosus neuroglian 0.0051 0.0045 0.0157
Echinococcus granulosus hypothetical protein 0.0093 0.0102 0.0352
Echinococcus multilocularis sex peptide receptor 0.0093 0.0102 0.0102
Trypanosoma brucei SNF1-related protein kinases, putative 0.0051 0.0045 0.0299
Entamoeba histolytica hypothetical protein 0.0073 0.0074 0.0627
Schistosoma mansoni biogenic amine receptor 0.0093 0.0102 0.0352
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0199 0.1723
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0063 0.0424
Loa Loa (eye worm) hypothetical protein 0.0062 0.006 0.0424
Schistosoma mansoni gabp alpha 0.0142 0.0167 0.0576
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0022 0.0006 0.0022
Echinococcus granulosus serine:threonine kinase SAD 1 0.0051 0.0045 0.0156
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0063 0.0061 0.021
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0061 0.021
Schistosoma mansoni neuropeptide receptor 0.0093 0.0102 0.0352
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.003 0.0201
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0104 0.0116 0.0171
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0006 0.0006
Brugia malayi histone deacetylase 1 (HD1) 0.087 0.1142 0.807
Brugia malayi photoreceptor-specific nuclear receptor 0.0063 0.0061 0.0429
Plasmodium falciparum chorismate synthase 0.5001 0.6673 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0104 0.0116 0.0338
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0063 0.0085
Trypanosoma cruzi aurora B kinase, putative 0.0178 0.0215 0.151
Loa Loa (eye worm) oxidoreductase 0.0064 0.0063 0.0444
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Echinococcus multilocularis neuropeptide FF receptor 2 0.0093 0.0102 0.0102
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0024 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0102 0.0102
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0067 0.0066 0.0558
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0093 0.0102 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0101 0.0691
Giardia lamblia Kinase, CMGC CDK 0.005 0.0045 0.0339
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.005 0.0045 0.0295
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.024 0.0299 0.2577
Echinococcus granulosus histone deacetylase 8 0.0442 0.0569 0.1968
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.2466 0.3279 1
Echinococcus granulosus histone deacetylase 0.1075 0.1416 0.4893
Mycobacterium ulcerans hypothetical protein 0.0035 0.0024 0.0027
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0251 0.0313 0.046
Loa Loa (eye worm) chloride channel 3 0.0022 0.0006 0.0042
Leishmania major 4-coumarate:coa ligase-like protein 0.0218 0.0269 0.1886
Schistosoma mansoni biogenic amine (5HT) receptor 0.0093 0.0102 0.0352
Trypanosoma cruzi histone deacetylase, putative 0.1075 0.1416 1
Brugia malayi Fli-1 protein 0.043 0.0553 0.3904
Trypanosoma brucei DNA polymerase eta, putative 0.0141 0.0166 0.1156
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0022 0.0006 0.0022
Brugia malayi hypothetical protein 0.0019 0.0002 0.0016
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0023 0.0007 0.0043
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Echinococcus granulosus histone deacetylase 6 0.1075 0.1416 0.4893
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0612 0.0797 0.5624
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0064 0.0063 0.0175
Schistosoma mansoni cpg binding protein 0.0123 0.0142 0.0491
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0198 0.0242 0.1702
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0016 0.0057
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0055 0.005 0.0334
Loa Loa (eye worm) Ulp1 protease 0.0038 0.0028 0.0198
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0024 0.0009 0.0129
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0249 0.031 0.219
Giardia lamblia Kinase, CMGC GSK 0.0054 0.0049 0.0377
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0022 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0066 0.0558
Schistosoma mansoni DNA ligase NAD-dependent 0.0232 0.0288 0.0994
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni hypothetical protein 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.015
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0102 0.0352
Brugia malayi hypothetical protein 0.0029 0.0016 0.0116
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0038 0.0028 0.0097
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0069 0.0069 0.0069
Leishmania major inosine-5-monophosphate dehydrogenase 0.0022 0.0006 0.0022
Echinococcus multilocularis g protein coupled receptor 0.0093 0.0102 0.0102
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0028 0.0198
Trichomonas vaginalis ap endonuclease, putative 0.004 0.003 0.0237
Schistosoma mansoni protein kinase subunit beta 0.0063 0.0061 0.021
Schistosoma mansoni tsg101-related 0.0057 0.0053 0.0185
Loa Loa (eye worm) glutaminase 2 0.0567 0.0736 0.5198
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Echinococcus granulosus expressed conserved protein 0.0133 0.0155 0.0535
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0064
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0016 0.0057
Giardia lamblia DINP protein human, muc B family 0.0127 0.0148 0.1247
Leishmania major protein kinase, putative 0.0178 0.0215 0.1501
Trypanosoma cruzi chloride channel protein, putative 0.0022 0.0006 0.0032
Trichomonas vaginalis replication factor C large subunit, putative 0.0067 0.0066 0.0558
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0022 0.0006 0.0032
Echinococcus multilocularis thyroid hormone receptor alpha 0.0063 0.0061 0.0061
Echinococcus multilocularis ETS transcription factor Elf 1 0.0021 0.0004 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Trypanosoma brucei DNA polymerase kappa, putative 0.0127 0.0148 0.1025
Brugia malayi Peroxidasin 0.0024 0.0009 0.0061
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0136 0.0399
Loa Loa (eye worm) hypothetical protein 0.0035 0.0024 0.017
Onchocerca volvulus 0.0093 0.0102 0.1523
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0011 0.0059
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.0107 0.0309
Onchocerca volvulus Histone deacetylase 10 homolog 0.0442 0.0569 0.8523
Echinococcus granulosus roundabout 2 0.0024 0.0009 0.003
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0091 0.0098 0.0098
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0056 0.0378
Schistosoma mansoni amine GPCR 0.0093 0.0102 0.0352
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0022 0.0006 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Toxoplasma gondii NEK kinase 0.0023 0.0007 0.0008
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0021 0.0073
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0072 0.0249
Toxoplasma gondii histone deacetylase HDAC4 0.0442 0.0569 0.085
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0178 0.0215 0.0744
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0093 0.0102 0.0719
Loa Loa (eye worm) hypothetical protein 0.0063 0.0061 0.0429
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0063 0.0061 0.0061
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0027 0.0037
Plasmodium vivax protein kinase Crk2 0.005 0.0045 0.0063
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0012 0.0075
Loa Loa (eye worm) hypothetical protein 0.0091 0.0099 0.0702
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0602 0.0783 0.2707
Trichomonas vaginalis importin beta-1, putative 0.0071 0.0072 0.061
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0047 0.032
Brugia malayi Thioredoxin reductase 0.0038 0.0028 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0063 0.0061 0.0429
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0056 0.0155
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0022 0.0006 0.0002
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0024 0.015
Schistosoma mansoni apoptosis regulator bax 0.0091 0.0098 0.034
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0024 0.0083
Plasmodium vivax histone deacetylase 2, putative 0.1075 0.1416 0.2119
Toxoplasma gondii histone kinase SNF1, putative 0.0051 0.0045 0.0064
Loa Loa (eye worm) hypothetical protein 0.0163 0.0195 0.1381
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0202 0.0248 0.175
Echinococcus multilocularis neuropeptide s receptor 0.0093 0.0102 0.0102
Echinococcus granulosus protein C ets 2 0.0021 0.0004 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.017 0.0205 0.1428
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0091 0.0098 0.034
Mycobacterium ulcerans monoamine oxidase 0.0104 0.0116 0.0165
Brugia malayi chloride channel protein 7 0.0022 0.0006 0.0042
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0026 0.0011 0.0011
Brugia malayi Dopamine receptor protein 2 0.0093 0.0102 0.0719
Trypanosoma cruzi GMP reductase 0.0022 0.0006 0.0032
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0093 0.0102 0.0719
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0242 0.0837
Leishmania major histone deacetylase, putative 0.087 0.1142 0.8066
Brugia malayi neuropeptide F receptor 0.0093 0.0102 0.0719
Onchocerca volvulus Neuropeptide F receptor homolog 0.0093 0.0102 0.1523
Loa Loa (eye worm) glutaminase 0.0567 0.0736 0.5198
Loa Loa (eye worm) hypothetical protein 0.0046 0.0038 0.0272
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0027 0.019
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0098 0.0108 0.0108
Onchocerca volvulus 0.0029 0.0015 0.023
Echinococcus multilocularis g-protein coupled receptor 0.0093 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0072 0.0249
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0022 0.0006 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Brugia malayi CHE-14 protein 0.0133 0.0156 0.11
Schistosoma mansoni RAR-like nuclear receptor 0.0063 0.0061 0.021
Trichomonas vaginalis antibiotic synthetase, putative 0.0064 0.0063 0.0526
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0021 0.0004 0.0032
Toxoplasma gondii ck2 beta subunit 0.0037 0.0027 0.0037
Schistosoma mansoni amine oxidase 0.0104 0.0116 0.0401
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0015 0.002
Entamoeba histolytica hypothetical protein 0.0073 0.0074 0.0627
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0022 0.0006 0.0006
Brugia malayi glutaminase DH11.1 0.0567 0.0736 0.5198
Brugia malayi hypothetical protein 0.0091 0.0099 0.0702
Brugia malayi Trypsin family protein 0.0024 0.0009 0.0064
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0093 0.0102 0.0102
Schistosoma mansoni amine GPCR 0.0093 0.0102 0.0352
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0012 0.0083
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0113 0.0129 0.0377
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0056 0.0056
Echinococcus multilocularis acetylcholinesterase 0.0541 0.0701 0.0701
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0009
Entamoeba histolytica Flap nuclease, putative 0.0055 0.005 0.0414
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0063 0.0085
Echinococcus granulosus tar DNA binding protein 0.0128 0.0149 0.0514
Echinococcus multilocularis glycoprotein Antigen 5 0.0024 0.0009 0.0009
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0027 0.0402
Trypanosoma cruzi DNA polymerase kappa, putative 0.017 0.0205 0.1437
Brugia malayi hypothetical protein 0.0067 0.0066 0.0469
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0031
Mycobacterium ulcerans acyl-CoA synthetase 0.0218 0.0269 0.0395
Brugia malayi CLC chloride channel protein 0.0022 0.0006 0.0042
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0022 0.0006 0.0002
Echinococcus granulosus lachesin 0.0024 0.0009 0.003
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0065 0.0064 0.0507
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0093 0.0102 0.0352
Schistosoma mansoni neuropeptide F-like receptor 0.0093 0.0102 0.0352
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.002 0.015
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0093 0.0102 0.0102
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0039 0.0136
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0131 0.0153 0.0528
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0054 0.0049 0.0325
Schistosoma mansoni nephrin 0.0051 0.0045 0.0157
Echinococcus granulosus lysine specific histone demethylase 1A 0.0104 0.0116 0.0401
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.002 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0066 0.0558
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1475 0.1952 0.292
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0051 0.0045 0.0319
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Echinococcus multilocularis nibrin 0.0067 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0061
Loa Loa (eye worm) hypothetical protein 0.0063 0.0061 0.0429
Giardia lamblia Hypothetical protein 0.0026 0.0011 0.0046
Trypanosoma cruzi metacaspase, putative 0.0026 0.0012 0.0075
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0028 0.0199
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0067 0.0066 0.0558
Loa Loa (eye worm) flap endonuclease-1 0.0055 0.005 0.0354
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0016 0.0057
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0027 0.0027
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0024 0.0024
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0142 0.0167 0.1177
Loa Loa (eye worm) histone deacetylase 7A 0.1075 0.1416 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0064 0.0063 0.0444
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Mycobacterium tuberculosis DNA ligase [NAD dependent] LigA (polydeoxyribonucleotide synthase [NAD+]) 0.0046 0.0039 0.0101
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0031
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0054 0.0049 0.0345
Mycobacterium tuberculosis Conserved protein 0.0022 0.0006 0.0002
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0063 0.0061 0.021
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0063 0.0424
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Onchocerca volvulus 0.0093 0.0102 0.1523
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0028 0.0221
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0028 0.0221
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0093 0.0102 0.0352
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0063 0.0061 0.0061
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1475 0.1952 0.292
Brugia malayi phosphofructokinase 0.0119 0.0136 0.0962
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0012 0.0042
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0102 0.0352
Leishmania major chloride channel protein, putative 0.0022 0.0006 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0316 0.2744
Echinococcus granulosus histone deacetylase 3 0.087 0.1142 0.3949
Brugia malayi G-protein coupled receptor 0.0093 0.0102 0.0719
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0102 0.0102
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0026 0.0011 0.0013
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0064 0.0063 0.0424
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0093 0.0102 0.0352
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0093 0.0102 0.0102
Echinococcus multilocularis neuroglian 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0063 0.0061 0.0429
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0136 0.117
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0091 0.0099 0.084
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0064 0.0063 0.0434
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0612 0.0797 0.5624
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0136 0.117
Onchocerca volvulus 0.0019 0.0002 0.0034
Echinococcus granulosus GPCR family 2 0.0115 0.0131 0.0453
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Loa Loa (eye worm) hypothetical protein 0.0062 0.006 0.0424
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0218 0.0269 0.0395
Schistosoma mansoni hypothetical protein 0.0091 0.0098 0.034
Onchocerca volvulus 0.0064 0.0063 0.094
Trypanosoma brucei histone deacetylase 2 0.0442 0.0569 0.401
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni DNA helicase recq1 0.0022 0.0006 0.0021
Trichomonas vaginalis set domain proteins, putative 0.0262 0.0327 0.2848
Plasmodium falciparum metacaspase-like protein 0.0026 0.0012 0.0015
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0104 0.0116 0.0401
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0115 0.0131 0.0453
Schistosoma mansoni terminal deoxycytidyl transferase 0.0113 0.0129 0.0445
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0063 0.0085
Loa Loa (eye worm) hypothetical protein 0.0063 0.0061 0.0429
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0102 0.0352
Loa Loa (eye worm) carboxylesterase 0.0091 0.0099 0.0702
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0476 0.0614 0.0614
Toxoplasma gondii CBS family protein 0.0022 0.0006 0.0006
Loa Loa (eye worm) Ulp1 protease 0.0091 0.0099 0.0697
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.003 0.0075
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0016 0.0016
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0644 0.084 0.1251
Brugia malayi Tachykinin-like peptides receptor 99D 0.0093 0.0102 0.0719
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0022 0.0006 0.0032
Brugia malayi ImpB/MucB/SamB family protein 0.0113 0.0129 0.091
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0015 0.002
Brugia malayi Trypsin-like protease protein 5 0.0024 0.0009 0.0064
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.002 0.015
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0027 0.018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.0107 0.0309
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.002 0.0027
Schistosoma mansoni retinoic acid receptor RXR 0.0063 0.0061 0.021
Echinococcus multilocularis roundabout 2 0.0024 0.0009 0.0009
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.003 0.042
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0063 0.0061 0.0908
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0251 0.0313 0.0939
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0104 0.0116 0.0116
Schistosoma mansoni acetylcholinesterase 0.0091 0.0099 0.0343
Entamoeba histolytica histone deacetylase, putative 0.087 0.1142 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0016 0.0247
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0094 0.0269
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0024 0.0161
Onchocerca volvulus 0.0104 0.0116 0.1738
Mycobacterium tuberculosis Conserved protein 0.0022 0.0006 0.0002
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0178 0.0215 0.0215
Plasmodium falciparum NIMA related kinase 4 0.0023 0.0007 0.0008
Schistosoma mansoni glutaminase 0.0567 0.0736 0.2544
Echinococcus multilocularis caspase 8 0.0026 0.0012 0.0012
Echinococcus granulosus g protein coupled receptor 0.0093 0.0102 0.0352
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.003 0.021
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0104 0.0116 0.0165
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0178 0.0215 0.0319
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0091 0.0099 0.084
Echinococcus multilocularis somatostatin receptor 0.0093 0.0102 0.0102
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0022 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni histone deacetylase 4 5 0.1075 0.1416 0.4893
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0091 0.0098 0.0098
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Brugia malayi CBS domain containing protein 0.0022 0.0006 0.0042
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0017 0.006
Brugia malayi hypothetical protein 0.0165 0.0198 0.1401
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0064 0.0063 0.0091
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0042
Echinococcus multilocularis peroxidasin 0.0024 0.0009 0.0009
Echinococcus granulosus acetylcholinesterase 0.0541 0.0701 0.2423
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0006 0.0027
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0063 0.0061 0.021
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Trypanosoma cruzi histone deacetylase, putative 0.1075 0.1416 1
Mycobacterium tuberculosis Probable reductase 0.0087 0.0094 0.0269
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0211 0.1828
Schistosoma mansoni zinc finger protein 0.0029 0.0016 0.0057
Loa Loa (eye worm) hypothetical protein 0.087 0.1142 0.807
Schistosoma mansoni chloride channel protein 0.0022 0.0006 0.0021
Onchocerca volvulus 0.0019 0.0002 0.0034
Schistosoma mansoni neuropeptide f receptor 76f 0.0093 0.0102 0.0352
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0115 0.0131 0.0131
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0027 0.0211
Echinococcus multilocularis sentrin specific protease 1 0.0038 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0311 0.0393 0.2779
Echinococcus multilocularis microtubule associated protein 2 0.2178 0.2893 0.2893
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0011 0.0069
Plasmodium falciparum metacaspase 1 0.0026 0.0012 0.0015
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0064 0.0063 0.0174
Echinococcus multilocularis tyrosine protein kinase otk 0.0024 0.0009 0.0009
Schistosoma mansoni chloride channel protein 0.0022 0.0006 0.0021
Loa Loa (eye worm) apoptosis regulator protein 0.0091 0.0098 0.0694
Schistosoma mansoni hypothetical protein 0.0129 0.0149 0.0516
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0019 0.0003 0.0043
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Toxoplasma gondii chorismate synthase, putative 0.5001 0.6673 1
Echinococcus multilocularis histone deacetylase 6 0.1075 0.1416 0.1416
Trichomonas vaginalis rotamase, putative 0.0069 0.007 0.0585
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0541 0.0701 0.2423
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0026 0.0011 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0063 0.0085
Brugia malayi protein C24B5.3 0.0019 0.0002 0.0016
Plasmodium vivax histone deacetylase, putative 0.0442 0.0569 0.085
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0149 0.1051
Loa Loa (eye worm) hypothetical protein 0.0163 0.0195 0.1381
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0284 0.0357 0.252
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0199 0.2981
Schistosoma mansoni ran 0.0065 0.0064 0.022
Echinococcus granulosus peptide allatostatin:somatostatin 0.0093 0.0102 0.0352
Echinococcus multilocularis conserved hypothetical protein 0.0029 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Onchocerca volvulus 0.0202 0.0248 0.3708
Brugia malayi G protein-coupled receptor 0.0093 0.0102 0.0719
Schistosoma mansoni opsin-like receptor 0.0093 0.0102 0.0352
Leishmania major protein kinase, putative 0.0023 0.0007 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Leishmania major metacaspase, putative 0.0026 0.0012 0.0065
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0064 0.0063 0.0444
Schistosoma mansoni DNA helicase recq5 0.0022 0.0006 0.0021
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0218 0.0269 0.1903
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0218 0.0269 0.0806
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0019 0.0066
Mycobacterium tuberculosis Conserved protein 0.0022 0.0006 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0218 0.0269 0.0395
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0064 0.0063 0.0175
Brugia malayi loechrig isoform VII 0.024 0.0299 0.2111
Loa Loa (eye worm) DR-78 0.0029 0.0016 0.0116
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0091 0.0099 0.084
Loa Loa (eye worm) hypothetical protein 0.0249 0.031 0.2189
Brugia malayi Protein kinase domain containing protein 0.005 0.0045 0.0314
Trypanosoma cruzi chloride channel protein, putative 0.0022 0.0006 0.0032
Schistosoma mansoni roundabout 0.0024 0.0009 0.003
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0045 0.0365
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0061
Trypanosoma cruzi GMP reductase 0.0022 0.0006 0.0032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0061 0.0429
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0136 0.0398
Trichomonas vaginalis AGC family protein kinase 0.0178 0.0215 0.1861
Schistosoma mansoni hypothetical protein 0.0093 0.0102 0.0352
Echinococcus granulosus ecdysone induced protein 78C 0.0063 0.0061 0.021
Loa Loa (eye worm) RecQ helicase 0.0022 0.0006 0.0043
Brugia malayi Fibronectin type III domain containing protein 0.0038 0.0028 0.02
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0067 0.0066 0.046
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0061
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0012 0.0083
Schistosoma mansoni importin beta-1 0.0088 0.0095 0.0327
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0005 0.0016
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0061
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.005 0.0045 0.0314
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0054 0.0049 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni cellular tumor antigen P53 0.0156 0.0186 0.0643
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0394 0.0504 0.0747
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0024 0.0009 0.0061
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.01 0.0686
Entamoeba histolytica hypothetical protein 0.0073 0.0074 0.0627
Echinococcus granulosus serotonin receptor 0.0093 0.0102 0.0352
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Schistosoma mansoni neuropeptide F-like receptor 0.0093 0.0102 0.0352
Leishmania major DNA polymerase kappa, putative 0.0035 0.0024 0.015
Schistosoma mansoni hypothetical protein 0.0023 0.0008 0.0029
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0064 0.0063 0.0444
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0022 0.0006 0.0006
Trypanosoma cruzi cdc2-related kinase 1 0.005 0.0045 0.0305
Leishmania major histone deacetylase, putative 0.087 0.1142 0.8066
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.002 0.0027
Schistosoma mansoni tyrosine kinase 0.0029 0.0015 0.0053
Loa Loa (eye worm) patched family protein 0.0019 0.0002 0.0016
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0047 0.032
Brugia malayi RNA, U transporter 1 0.025 0.0312 0.2201
Loa Loa (eye worm) hypothetical protein 0.0632 0.0823 0.5815
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0117 0.0133 0.0941
Brugia malayi Trypsin family protein 0.0024 0.0009 0.0064
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0023 0.0007 0.0008
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0012 0.008
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0024 0.0009 0.0009
Brugia malayi sulfakinin receptor protein 0.0093 0.0102 0.0719
Brugia malayi Pre-SET motif family protein 0.0035 0.0024 0.017
Brugia malayi acetyltransferase, GNAT family protein 0.0159 0.0189 0.1337
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0028 0.0221
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0065 0.0064 0.0064
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0149 0.1051
Onchocerca volvulus 0.0024 0.0009 0.0136
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0012 0.008
Echinococcus granulosus tm gpcr rhodopsin 0.0093 0.0102 0.0352
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0093 0.0102 0.0719
Plasmodium vivax metacaspase 1, putative 0.0026 0.0012 0.0015
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Echinococcus multilocularis casein kinase ii subunit beta 0.0037 0.0027 0.0027
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0064 0.0063 0.0175
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0115 0.0131 0.0926
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Echinococcus multilocularis caspase 3 0.0072 0.0073 0.0073
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0093 0.0102 0.0719
Mycobacterium tuberculosis Conserved hypothetical protein 0.0323 0.0409 0.1232
Loa Loa (eye worm) hypothetical protein 0.0063 0.0061 0.0429
Brugia malayi Patched related family protein 4 0.0019 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.033
Trypanosoma brucei importin beta-1 subunit, putative 0.0088 0.0095 0.0649
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0029 0.0015 0.002
Schistosoma mansoni ets-related 0.0021 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0115 0.0131 0.0926
Brugia malayi AMP-binding enzyme family protein 0.0218 0.0269 0.1903
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0063 0.0061 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0083
Onchocerca volvulus 0.0067 0.0066 0.0995
Loa Loa (eye worm) hypothetical protein 0.0067 0.0066 0.0469
Echinococcus granulosus expressed conserved protein 0.0292 0.0368 0.1273
Echinococcus granulosus nibrin 0.0067 0.0066 0.023
Echinococcus multilocularis replication factor c subunit 1 0.0067 0.0066 0.0066
Trichomonas vaginalis AGC family protein kinase 0.0178 0.0215 0.1861
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0005 0.0016
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0039 0.0056
Echinococcus multilocularis g protein coupled receptor 0.0093 0.0102 0.0102
Plasmodium vivax importin-beta 2, putative 0.0088 0.0095 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Brugia malayi RE40412p 0.0029 0.0015 0.0109
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0133 0.0156 0.11
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0064 0.0063 0.0217
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0024 0.0009 0.003
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0012 0.0015
Mycobacterium ulcerans DNA polymerase IV 0.017 0.0205 0.0298
Trypanosoma cruzi cdc2-related kinase 1 0.005 0.0045 0.0305
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0093 0.0102 0.0352
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0056 0.0076
Brugia malayi F/Y-rich N-terminus family protein 0.0037 0.0026 0.0186
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.002 0.0027
Brugia malayi Serotonin receptor 0.0093 0.0102 0.0719
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0248 0.031 0.107
Echinococcus granulosus ETS domain containing protein Elk 1 0.0021 0.0004 0.0016
Echinococcus granulosus cpg binding protein 0.0123 0.0142 0.0491
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.0092 0.0643
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0133 0.0156 0.11
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.003 0.0041
Brugia malayi ImpB/MucB/SamB family protein 0.0141 0.0166 0.1174
Schistosoma mansoni hypothetical protein 0.0024 0.0009 0.0031
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0071 0.0072 0.061
Echinococcus multilocularis caspase 2 0.0026 0.0012 0.0012
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0063 0.0175
Entamoeba histolytica hypothetical protein 0.0073 0.0074 0.0627
Brugia malayi hypothetical protein 0.0104 0.0116 0.082
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0094 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Trypanosoma cruzi DNA polymerase kappa, putative 0.017 0.0205 0.1437
Trypanosoma cruzi histone deacetylase 1, putative 0.087 0.1142 0.8068
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0024 0.0009 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.008
Loa Loa (eye worm) ets-domain-containing protein 0.0021 0.0004 0.0032
Onchocerca volvulus 0.0262 0.0327 0.49
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0069 0.0069 0.0238
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0199 0.1723
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0178 0.0215 0.0215
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0012 0.008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0061
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0012 0.008
Schistosoma mansoni tsg101-related 0.0057 0.0053 0.0185
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0077 0.008 0.008
Trichomonas vaginalis helicase, putative 0.0026 0.0012 0.0083
Onchocerca volvulus 0.0093 0.0102 0.1523
Schistosoma mansoni ets-related 0.043 0.0553 0.191
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.087 0.1142 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0077 0.008 0.0553
Loa Loa (eye worm) latrophilin receptor protein 2 0.0115 0.0131 0.0926
Trichomonas vaginalis histone deacetylase, putative 0.087 0.1142 1
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0149 0.1051
Trypanosoma brucei Metacaspase-4 0.0026 0.0012 0.0065
Brugia malayi Carboxylesterase family protein 0.0091 0.0099 0.0702
Echinococcus granulosus replication factor c subunit 1 0.0067 0.0066 0.023
Schistosoma mansoni tsg101-related 0.0047 0.0039 0.0136
Loa Loa (eye worm) hypothetical protein 0.0067 0.0066 0.0469
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0027 0.0402
Echinococcus granulosus sentrin specific protease 1 0.0038 0.0028 0.0097
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0024 0.0009 0.0009
Schistosoma mansoni neuropeptide receptor 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0504 0.0652 0.2254
Giardia lamblia Kinase, CMGC GSK 0.0054 0.0049 0.0377
Loa Loa (eye worm) hypothetical protein 0.0623 0.0811 0.5727
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0027 0.0093
Brugia malayi cell division control protein 2 homolog 0.005 0.0045 0.0314
Loa Loa (eye worm) patched family protein 0.0019 0.0002 0.0016
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0022 0.0006 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.017 0.0205 0.1428
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0009 0.0009
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.017 0.0205 0.1428
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0102 0.0102
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.0088 0.0095 0.0669
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0006 0.0022
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0136 0.0944
Giardia lamblia Fructose-bisphosphate aldolase 0.0447 0.0576 0.5012
Echinococcus multilocularis protein C ets 2 0.0021 0.0004 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0049 0.0403
Entamoeba histolytica protein kinase, putative 0.0198 0.0242 0.21
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Loa Loa (eye worm) G-protein coupled receptor 0.0093 0.0102 0.0719
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0136 0.0962
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.02
Brugia malayi RE15519p 0.0093 0.0102 0.0719
Trypanosoma brucei metacaspase 5, putative 0.0026 0.0012 0.0065
Schistosoma mansoni histamine h1 receptor 0.0093 0.0102 0.0352
Plasmodium falciparum acyl-CoA synthetase 0.0163 0.0195 0.029
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0093 0.0102 0.0719
Loa Loa (eye worm) hypothetical protein 0.0442 0.0569 0.4022
Echinococcus multilocularis fmrfamide receptor 0.0093 0.0102 0.0102
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Brugia malayi polk-prov protein 0.0092 0.01 0.0705
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0045 0.0045
Echinococcus multilocularis caspase 0.0098 0.0108 0.0108
Onchocerca volvulus 0.0019 0.0002 0.0034
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0006 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0102 0.0352
Brugia malayi N-terminal motif family protein 0.0182 0.0221 0.1561
Trypanosoma cruzi metacaspase, putative 0.0026 0.0012 0.0075
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0091 0.0099 0.084
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0024 0.0009 0.0064
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0011 0.0073
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0178 0.0215 0.0744
Schistosoma mansoni DNA polymerase eta 0.0141 0.0166 0.0574
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0187 0.0227 0.0785
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0093 0.0102 0.0102
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0149 0.0514
Echinococcus granulosus tachykinin peptides receptor 99D 0.0093 0.0102 0.0352
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0178 0.0215 0.0743
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0028 0.0221
Loa Loa (eye worm) histone deacetylase 0.1075 0.1416 1
Echinococcus granulosus flap endonuclease 1 0.0055 0.005 0.0173
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0091 0.0098 0.0694
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0064 0.0063 0.0085
Echinococcus granulosus caspase 2 0.0026 0.0012 0.0042
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0016 0.0247
Trypanosoma cruzi DNA polymerase kappa, putative 0.017 0.0205 0.1437
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0063 0.0061 0.021
Brugia malayi steroid hormone receptor 0.0063 0.0061 0.0429
Brugia malayi Cell death protein 3 precursor 0.0026 0.0012 0.0085
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0077 0.008 0.0275
Echinococcus granulosus neuropeptide receptor 0.0093 0.0102 0.0352
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.0004 0.0016
Echinococcus multilocularis protoporphyrinogen oxidase 0.0104 0.0116 0.0116
Entamoeba histolytica protein kinase domain containing protein 0.0178 0.0215 0.1861
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0061
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0064
Onchocerca volvulus 0.0024 0.0009 0.0136
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0198 0.0242 0.1702
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0063 0.0061 0.0061
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0093 0.0102 0.0102
Brugia malayi DKFZp564C0469 protein 0.0067 0.0066 0.0469
Brugia malayi hypothetical protein 0.0073 0.0074 0.0526
Echinococcus granulosus dro:myosuppressin receptor 0.0093 0.0102 0.0352
Trypanosoma cruzi NIMA-related kinase, putative 0.0023 0.0007 0.0043
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0024 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0092 0.01 0.0705
Brugia malayi Importin beta-1 subunit 0.0088 0.0095 0.0669
Loa Loa (eye worm) fli-1 protein 0.043 0.0553 0.3904
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0016 0.0057
Loa Loa (eye worm) hypothetical protein 0.0121 0.0139 0.0983
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0064 0.0063 0.0174
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0028 0.0198
Onchocerca volvulus 0.0093 0.0102 0.1523
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.0242 0.21
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0064 0.0063 0.0174
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0061 0.0061
Echinococcus granulosus sentrin specific protease 8 0.0091 0.0099 0.0341
Brugia malayi putative serine/threonine kinase SADA gamma 0.0051 0.0045 0.0319
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0093 0.0102 0.0352
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0051 0.0045 0.0045
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0093 0.0102 0.0352
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0187 0.0227 0.4442
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0094 0.0269
Schistosoma mansoni amine GPCR 0.0093 0.0102 0.0352
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.005 0.0045 0.0295
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0012 0.008
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0019 0.0003 0.0001
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0149 0.0149
Echinococcus multilocularis cpg binding protein 0.0123 0.0142 0.0142
Toxoplasma gondii ATPase, AAA family protein 0.0067 0.0066 0.0096
Mycobacterium ulcerans hypothetical protein 0.0218 0.0269 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0156 0.1341
Echinococcus granulosus acetylcholinesterase 0.0541 0.0701 0.2423
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0064 0.0063 0.0085
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0093 0.0102 0.0719
Echinococcus multilocularis cyclin dependent kinase 0.005 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.015
Trypanosoma brucei DNA polymerase kappa, putative 0.017 0.0205 0.1428
Echinococcus multilocularis carboxylesterase 5A 0.0541 0.0701 0.0701
Leishmania major serine/threonine-protein kinase, putative 0.0023 0.0007 0.0032
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0077 0.008 0.0647
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0016 0.0016
Chlamydia trachomatis chorismate synthase 0.5001 0.6673 1
Echinococcus granulosus transmembrane protease serine 3 0.0024 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.0275 0.0346 0.2441
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0061
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0022 0.0006 0.0032
Echinococcus granulosus 7TM GPCR rhodopsin 0.0093 0.0102 0.0352
Plasmodium falciparum serine/threonine protein kinase, putative 0.0178 0.0215 0.0319
Entamoeba histolytica protein kinase, putative 0.0178 0.0215 0.1861
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0077 0.008 0.008
Schistosoma mansoni cpg binding protein 0.0117 0.0133 0.046
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0051 0.0045 0.0309
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0016 0.0016
Leishmania major chloride channel protein, putative 0.0022 0.0006 0.0022
Echinococcus multilocularis histone deacetylase 8 0.0442 0.0569 0.0569
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.017 0.0205 0.177
Brugia malayi hypothetical protein 0.0457 0.0589 0.4161
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0077 0.008 0.0673
Echinococcus multilocularis histone deacetylase 0.1075 0.1416 0.1416
Loa Loa (eye worm) patched family protein 0.0019 0.0002 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.031 0.1072
Schistosoma mansoni hypothetical protein 0.0249 0.031 0.1071
Loa Loa (eye worm) hypothetical protein 0.0091 0.0099 0.0702
Entamoeba histolytica protein kinase domain containing protein 0.0054 0.0049 0.0403
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0011 0.0073
Trypanosoma cruzi UDP-galactopyranose mutase 0.0104 0.0116 0.0811
Echinococcus multilocularis serotonin receptor 0.0093 0.0102 0.0102
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0029 0.0015 0.002
Leishmania major CBS domain protein, conserved 0.0022 0.0006 0.0022
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0051 0.0045 0.0309
Echinococcus granulosus Niemann Pick C1 protein 0.0311 0.0393 0.136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Plasmodium falciparum serine/threonine protein kinase KIN 0.0051 0.0045 0.0064
Loa Loa (eye worm) hypothetical protein 0.0194 0.0236 0.1668
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0099 0.0343
Schistosoma mansoni flap endonuclease-1 0.0049 0.0043 0.0149
Trichomonas vaginalis DNA polymerase eta, putative 0.017 0.0205 0.177
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.005 0.0045 0.0154
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0115 0.0131 0.0131
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0022 0.0006 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.008 0.0673
Brugia malayi hypothetical protein 0.0052 0.0047 0.033
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0099 0.0343
Brugia malayi Latrophilin receptor protein 2 0.0115 0.0131 0.0926
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0012 0.0015
Echinococcus multilocularis dnaJ subfamily B 0.0845 0.1108 0.1108
Leishmania major DNA damage repair protein, putative 0.0035 0.0024 0.015
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0047 0.0067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0154 0.0184 0.0544
Loa Loa (eye worm) hypothetical protein 0.0182 0.0221 0.1561
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.002 0.015
Onchocerca volvulus 0.0019 0.0002 0.0034
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0022 0.0006 0.0022
Trypanosoma cruzi DNA polymerase kappa, putative 0.017 0.0205 0.1437
Echinococcus multilocularis G protein coupled receptor 139 0.0093 0.0102 0.0102
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0022 0.0006 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0063 0.0085
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0016 0.0057
Onchocerca volvulus 0.0165 0.0198 0.2969
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0068 0.0067 0.0566
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0045 0.0365
Leishmania major acetyl-CoA synthetase, putative 0.0064 0.0063 0.0424
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0068 0.0067 0.0457
Plasmodium vivax chorismate synthase 0.5001 0.6673 1
Echinococcus granulosus roundabout 2 0.0024 0.0009 0.003
Echinococcus multilocularis GPCR, family 2 0.0115 0.0131 0.0131
Brugia malayi G-protein coupled receptor 0.0093 0.0102 0.0719
Toxoplasma gondii histone deacetylase HDAC5 0.0442 0.0569 0.085
Trichomonas vaginalis flap endonuclease-1, putative 0.0055 0.005 0.0414
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.0004 0.0016
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0022 0.0006 0.0021
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0275 0.0346 0.0346
Onchocerca volvulus 0.0022 0.0006 0.0089
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0136 0.0953
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0065 0.0064 0.0092
Loa Loa (eye worm) hypothetical protein 0.0091 0.0099 0.0702
Echinococcus granulosus importin subunit beta 1 0.0088 0.0095 0.0327
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0039 0.0321
Echinococcus multilocularis histone deacetylase 6 0.1094 0.1441 0.1441
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0016 0.0016
Brugia malayi conserved hypotetical protein 0.0029 0.0016 0.0116
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0024 0.015
Plasmodium falciparum replication factor C subunit 1, putative 0.0067 0.0066 0.0096
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0077 0.008 0.0275
Echinococcus multilocularis BRCA1 associated protein 0.0019 0.0003 0.0003
Echinococcus granulosus protein kinase shaggy 0.0054 0.0049 0.0169
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni histone deacetylase 1 2 3 0.0442 0.0569 0.1968
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0021 0.015
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0064 0.0063 0.0218
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0024 0.0009 0.0009
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0051 0.0045 0.0064
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0017 0.0017
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0026 0.0011 0.0013
Echinococcus granulosus cyclin dependent kinase 0.005 0.0045 0.0154
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0198 0.0242 0.1694
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0026 0.0011 0.0073
Entamoeba histolytica cell division protein kinase 2, putative 0.005 0.0045 0.0365
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0064
Onchocerca volvulus 0.0091 0.0099 0.1486
Loa Loa (eye worm) hypothetical protein 0.0104 0.0116 0.082
Brugia malayi protein C24B5.3 0.0019 0.0002 0.0016
Echinococcus granulosus serine:threonine protein kinase Nek1 0.0018 0.0001 0.0005
Loa Loa (eye worm) chloride channel protein 7 0.0022 0.0006 0.0042
Loa Loa (eye worm) MH2 domain-containing protein 0.0252 0.0315 0.2222
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0038 0.0028 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0063 0.0061 0.0429
Trichomonas vaginalis hypothetical protein 0.0033 0.0022 0.0165
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0064 0.0063 0.0091
Trypanosoma brucei cdc2-related kinase 1 0.005 0.0045 0.0295
Schistosoma mansoni acetyl-CoA synthetase 0.0064 0.0063 0.0217
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0028 0.0221
Trypanosoma brucei histone deacetylase 1 0.087 0.1142 0.8066
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0024 0.0161
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0045 0.0314
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.082 0.1075 0.3266
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0218 0.0269 0.0806
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.002 0.0021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0187 0.0227 0.0227
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0011 0.0079
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0136 0.0962
Brugia malayi Pax transcription activation domain interacting protein 0.0067 0.0066 0.0469
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0136 0.117
Entamoeba histolytica acyl-CoA synthetase, putative 0.0218 0.0269 0.2338
Brugia malayi DNA-binding protein D-ETS-3 0.0021 0.0004 0.0032
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0171 0.0206 0.1782
Brugia malayi RE40412p 0.0029 0.0015 0.0109
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0028 0.0189
Echinococcus granulosus GA binding protein alpha chain 0.0142 0.0167 0.0576
Echinococcus multilocularis protein kinase shaggy 0.0054 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0218 0.0269 0.1903
Schistosoma mansoni hypothetical protein 0.0129 0.0149 0.0516
Echinococcus granulosus neuropeptide FF receptor 2 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0021 0.0073
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0024 0.0033
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Echinococcus multilocularis transmembrane protease serine 3 0.0024 0.0009 0.0009
Schistosoma mansoni rotamase 0.0069 0.007 0.0241
Loa Loa (eye worm) AUR protein kinase 0.0178 0.0215 0.1519
Leishmania major histone deacetylase, putative 0.1075 0.1416 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0276
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0093 0.0102 0.0352
Plasmodium vivax glutathione reductase, putative 0.0038 0.0028 0.0039
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0006 0.0043
Entamoeba histolytica Ran family GTPase 0.0065 0.0064 0.0533
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0093 0.0102 0.0719
Trichomonas vaginalis histone deacetylase, putative 0.087 0.1142 1
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0024 0.0009 0.0009
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.0063 0.0061 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.017 0.0205 0.1428
Echinococcus multilocularis enteropeptidase 0.0024 0.0009 0.0009
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0024 0.0161
Trypanosoma brucei unspecified product 0.0156 0.0186 0.1295
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0045 0.0156
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0093 0.0102 0.0352
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0102 0.0352
Toxoplasma gondii peptidylprolyl isomerase 0.0068 0.0067 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0063 0.0061 0.0429
Toxoplasma gondii histone deacetylase HDAC2 0.087 0.1142 0.1709
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0026 0.0011 0.0039
Entamoeba histolytica hypothetical protein 0.0067 0.0066 0.0558
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0007 0.0026
Leishmania major hypothetical protein, unknown function 0.0029 0.0015 0.0088
Loa Loa (eye worm) hypothetical protein 0.0132 0.0153 0.1084
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0113 0.0129 0.091
Trypanosoma cruzi metacaspase, putative 0.0026 0.0012 0.0075
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.003 0.0191
Loa Loa (eye worm) transcription factor SMAD2 0.0252 0.0315 0.2222
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0038 0.0028 0.0098
Schistosoma mansoni hypothetical protein 0.0073 0.0074 0.0257
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0064 0.0063 0.0085
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0093 0.0102 0.0102
Echinococcus granulosus histone deacetylase 7 0.1075 0.1416 0.4893
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0054 0.0049 0.0345
Loa Loa (eye worm) carboxylesterase 0.0541 0.0701 0.4951
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0064
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Schistosoma mansoni cell adhesion molecule 0.0049 0.0043 0.0149
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0064 0.0063 0.0444
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0102 0.0352
Echinococcus granulosus lysine specific histone demethylase 1A 0.0104 0.0116 0.0401
Trypanosoma brucei aurora B kinase 0.0178 0.0215 0.1501
Echinococcus granulosus tm gpcr rhodopsin 0.0093 0.0102 0.0352
Loa Loa (eye worm) patched family protein 0.0019 0.0002 0.0016
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0113 0.0129 0.0129
Trichomonas vaginalis histone deacetylase, putative 0.087 0.1142 1
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0022 0.0006 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0063 0.0444
Loa Loa (eye worm) hypothetical protein 0.0104 0.0116 0.082
Echinococcus granulosus BC026374 protein S09 family 0.0091 0.0099 0.0343
Leishmania major UDP-galactopyranose mutase 0.0104 0.0116 0.0801
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0038 0.0028 0.0039
Onchocerca volvulus Tyrosine kinase homolog 0.0516 0.0668 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0024 0.0009 0.0009
Schistosoma mansoni amine oxidase 0.0104 0.0116 0.0401
Schistosoma mansoni nuclear hormone receptor 0.0063 0.0061 0.021
Giardia lamblia Kinase, CMGC CDK 0.005 0.0045 0.0339
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0074 0.0257
Echinococcus granulosus cyclin dependent kinase 5 0.005 0.0045 0.0154
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0021 0.0005 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0045 0.0154
Mycobacterium tuberculosis Carboxylesterase LipT 0.0091 0.0099 0.0287
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0024 0.0083
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0069 0.0069 0.01
Echinococcus multilocularis neuropeptides capa receptor 0.0093 0.0102 0.0102
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0086 0.0092 0.0633
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0085
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0021 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.0006 0.0035
Entamoeba histolytica protein kinase , putative 0.0178 0.0215 0.1861
Onchocerca volvulus Protein ultraspiracle homolog 0.0063 0.0061 0.0908
Echinococcus granulosus GTP binding nuclear protein Ran 0.0065 0.0064 0.022
Brugia malayi Histone deacetylase family protein 0.1075 0.1416 1
Schistosoma mansoni topbp1 0.0067 0.0066 0.023
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0394 0.0504 0.8743
Brugia malayi TAR-binding protein 0.0128 0.0149 0.1051
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0021 0.015
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0063 0.0061 0.021
Schistosoma mansoni histone deacetylase 0.087 0.1142 0.3949
Schistosoma mansoni hypothetical protein 0.0129 0.0149 0.0516
Echinococcus granulosus caspase 3 0.0072 0.0073 0.0252
Echinococcus multilocularis fmrfamide receptor 0.0093 0.0102 0.0102
Echinococcus granulosus histone acetyltransferase KAT2B 0.0154 0.0183 0.0634
Brugia malayi nuclear receptor RXR 0.0029 0.0016 0.0116
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0056 0.0195
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Onchocerca volvulus 0.0024 0.0009 0.0136
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0023 0.0007 0.0032
Giardia lamblia Aurora kinase 0.0178 0.0215 0.1839
Schistosoma mansoni hypothetical protein 0.0129 0.0149 0.0516
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0021 0.0073
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0022 0.0006 0.0002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0032
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.0006 0.0024
Onchocerca volvulus 0.0064 0.0063 0.094
Loa Loa (eye worm) hypothetical protein 0.0457 0.0589 0.4161
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0006 0.0022
Brugia malayi Dopamine receptor protein 1 0.0093 0.0102 0.0719
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Echinococcus granulosus BRCA1 associated protein 0.0019 0.0003 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0187 0.0227 0.1603
Loa Loa (eye worm) hypothetical protein 0.0063 0.0061 0.0429
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0016 0.0116
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0012 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0102 0.0102
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0027 0.0037
Brugia malayi putative neuropeptide receptor NPR1 0.0093 0.0102 0.0719
Schistosoma mansoni hypothetical protein 0.0845 0.1108 0.383
Onchocerca volvulus 0.0019 0.0002 0.0034
Echinococcus multilocularis neuropeptide receptor A26 0.0093 0.0102 0.0102
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.087 0.1142 1
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0022 0.0006 0.0021
Brugia malayi Voltage gated chloride channel family protein 0.0022 0.0006 0.0042
Echinococcus multilocularis dna polymerase eta 0.0141 0.0166 0.0166
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0067 0.0066 0.045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0644 0.084 0.1251
Plasmodium vivax histone deacetylase, putative 0.1075 0.1416 0.2119
Schistosoma mansoni patched 1 0.0133 0.0156 0.0538
Trypanosoma brucei NIMA-related protein kinase 0.0023 0.0007 0.0032
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0016 0.0057
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0045 0.0314
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.02
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0038 0.0028 0.0098
Loa Loa (eye worm) hypothetical protein 0.0132 0.0153 0.1084
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0026 0.0011 0.0039
Echinococcus granulosus tumor protein p63 0.1067 0.1405 0.4857
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0061 0.0429
Trypanosoma cruzi histone deacetylase 1, putative 0.087 0.1142 0.8068
Toxoplasma gondii exonuclease III APE 0.004 0.003 0.0041
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0159 0.0189 0.0654
Schistosoma mansoni biogenic amine receptor 0.0093 0.0102 0.0352
Schistosoma mansoni lozenge 0.0057 0.0054 0.0186
Echinococcus granulosus aurora kinase A 0.0178 0.0215 0.0743
Trichomonas vaginalis CAMK family protein kinase 0.0023 0.0007 0.004
Echinococcus multilocularis Niemann Pick C1 protein 0.0311 0.0393 0.0393
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0113 0.0129 0.0445
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0063 0.0061 0.0429
Echinococcus multilocularis Immunoglobulin 0.0038 0.0028 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0187 0.0227 0.0785
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0056 0.0076
Onchocerca volvulus 0.0064 0.0063 0.094
Brugia malayi hypothetical protein 0.0069 0.0069 0.0486
Chlamydia trachomatis DNA ligase 0.0214 0.0264 0.0387
Trichomonas vaginalis STE family protein kinase 0.0023 0.0007 0.004
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0023 0.0007 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0102 0.0352
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Echinococcus multilocularis orexin receptor type 2 0.0093 0.0102 0.0102
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.002 0.015
Echinococcus multilocularis histone deacetylase 1 0.087 0.1142 0.1142
Leishmania major importin beta-1 subunit, putative 0.0071 0.0072 0.0492
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0063 0.0061 0.0429
Onchocerca volvulus 0.0024 0.0009 0.0136
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.032 0.0405 0.1221
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0178 0.0215 0.1861
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0022 0.0006 0.0006
Brugia malayi G protein-coupled receptor F59B2.13 0.0093 0.0102 0.0719
Trichomonas vaginalis spcc417.12 protein, putative 0.0091 0.0099 0.0846
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0012 0.0083
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0006 0.0006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0012 0.008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0063 0.0061 0.021
Onchocerca volvulus 0.0035 0.0024 0.0361
Loa Loa (eye worm) hypothetical protein 0.0623 0.0811 0.5727
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0083
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0063 0.0061 0.021
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0077 0.008 0.0543
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0051 0.0045 0.0299
Echinococcus granulosus G protein coupled receptor 139 0.0093 0.0102 0.0352
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0316 0.2744
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0003 0.0011
Loa Loa (eye worm) AUR protein kinase 0.0178 0.0215 0.1519
Brugia malayi putative neuropeptide receptor 0.0093 0.0102 0.0719
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0017 0.0017
Echinococcus multilocularis geminin 0.0515 0.0666 0.0666
Brugia malayi Trypsin family protein 0.0024 0.0009 0.0064
Schistosoma mansoni nuclear receptor 0.0029 0.0016 0.0057
Brugia malayi serine/threonine kinase 12 0.0178 0.0215 0.1519
Echinococcus granulosus H:Cl exchange transporter 7 0.0022 0.0006 0.0021
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0028 0.02
Schistosoma mansoni hypothetical protein 0.0115 0.0131 0.0453
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0011 0.0073
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.0063 0.0061 0.021
Toxoplasma gondii zinc finger CDGSH-type domain-containing protein 0.0029 0.0015 0.002
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0027 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0056 0.0195
Schistosoma mansoni vesicular amine transporter 0.0038 0.0028 0.0098
Loa Loa (eye worm) histone deacetylase 1 0.087 0.1142 0.807
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0039 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni myosin xvIII 0.0093 0.0102 0.0352
Echinococcus multilocularis ETS transcription factor Elf 5 0.0021 0.0004 0.0004
Schistosoma mansoni chloride channel protein 0.0022 0.0006 0.0021
Onchocerca volvulus Cell death protein 3 homolog 0.0026 0.0012 0.018
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0067 0.0066 0.0558
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.02
Loa Loa (eye worm) hypothetical protein 0.0163 0.0195 0.1381
Mycobacterium ulcerans DNA polymerase IV 0.017 0.0205 0.0298
Entamoeba histolytica protein kinase, putative 0.0178 0.0215 0.1861
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0064 0.0063 0.0434
Loa Loa (eye worm) hypothetical protein 0.0104 0.0116 0.082
Brugia malayi hypothetical protein 0.0029 0.0016 0.0116
Loa Loa (eye worm) hypothetical protein 0.0067 0.0066 0.0469
Leishmania major hypothetical protein, conserved 0.0117 0.0133 0.0923
Plasmodium vivax hypothetical protein, conserved 0.0104 0.0116 0.0171
Brugia malayi Histone deacetylase 1 0.087 0.1142 0.807
Echinococcus granulosus glycoprotein Antigen 5 0.0024 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0061
Echinococcus granulosus peroxidasin 0.0024 0.0009 0.003
Echinococcus multilocularis sentrin specific protease 8 0.0091 0.0099 0.0099
Toxoplasma gondii histone deacetylase HDAC1 0.1075 0.1416 0.2119
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0021 0.0004 0.0032
Echinococcus multilocularis ubiquitin specific protease 41 0.0077 0.008 0.008
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0149 0.0514
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.0004 0.0004
Loa Loa (eye worm) loechrig isoform VII 0.024 0.0299 0.2111
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0009 0.0031
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0056 0.0195
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0064 0.0063 0.0091
Schistosoma mansoni protein kinase 0.0178 0.0215 0.0743
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.032 0.0405 0.0599
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0049 0.0043 0.0149
Echinococcus granulosus ETS transcription factor Elf 1 0.0021 0.0004 0.0016
Trypanosoma brucei chrX additional, unordered contigs 0.0035 0.0024 0.015
Loa Loa (eye worm) G-protein coupled receptor 0.0093 0.0102 0.0719
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0024 0.0009 0.0061
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0104 0.0116 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0199 0.1723
Brugia malayi Nuclear hormone receptor-like 1 0.0063 0.0061 0.0429
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Schistosoma mansoni alkaline phosphatase 0.0178 0.0215 0.0744
Brugia malayi serine/threonine protein kinase 6 0.0178 0.0215 0.1519
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0066 0.0558
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0021 0.0004 0.0004
Trypanosoma brucei metacaspase 0.0026 0.0012 0.0065
Mycobacterium ulcerans glutaminase 0.0567 0.0736 0.1095
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0066 0.046
Leishmania major acetyl-CoA synthetase, putative 0.0064 0.0063 0.0424
Echinococcus multilocularis histone deacetylase 7 0.1075 0.1416 0.1416
Brugia malayi Prion-like- 0.0024 0.0009 0.0061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Brugia malayi Immunoglobulin I-set domain containing protein 0.0553 0.0717 0.5066
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0083
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0029 0.0015 0.002
Brugia malayi nuclear receptor NHR-67 0.0029 0.0016 0.0116
Schistosoma mansoni hypothetical protein 0.0515 0.0666 0.2302
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0065 0.0064 0.043
Loa Loa (eye worm) glutathione reductase 0.0038 0.0028 0.0199
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0644 0.084 0.2548
Trypanosoma cruzi UDP-galactopyranose mutase 0.0104 0.0116 0.0811
Plasmodium falciparum flap endonuclease 1 0.0055 0.005 0.0072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.01 0.0686
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0198 0.0242 0.1711
Schistosoma mansoni histone deacetylase hda2 0.1094 0.1441 0.4983
Echinococcus granulosus biogenic amine 5HT receptor 0.0093 0.0102 0.0352
Echinococcus granulosus carboxylesterase 5A 0.0541 0.0701 0.2423
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0067 0.0066 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0316 0.2744
Brugia malayi intracellular kinase 0.0054 0.0049 0.0345
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0102 0.0352
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0005 0.0027
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0026 0.0011 0.0059
Loa Loa (eye worm) hypothetical protein 0.0541 0.0701 0.4951
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0077 0.008 0.0553
Loa Loa (eye worm) hypothetical protein 0.0069 0.0069 0.0486
Mycobacterium ulcerans dehydrogenase 0.0104 0.0116 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0063 0.0061 0.0429
Plasmodium falciparum thioredoxin reductase 0.0038 0.0028 0.0039
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0028 0.0221
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0027 0.0037
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0022 0.0006 0.0016
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0027 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0061 0.0429
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0065 0.0064 0.0092
Trypanosoma brucei trypanothione reductase 0.0038 0.0028 0.0179
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0099 0.0343
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0149 0.0514
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0024 0.0033
Schistosoma mansoni protein kinase subunit gamma 0.024 0.0299 0.1033
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0102 0.0352
Echinococcus granulosus expressed protein 0.0069 0.007 0.0241
Entamoeba histolytica protein kinase, putative 0.0054 0.0049 0.0403
Loa Loa (eye worm) acetylcholinesterase 1 0.0541 0.0701 0.4951
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0127 0.0148 0.1025
Brugia malayi Carboxylesterase family protein 0.0091 0.0099 0.0702
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0022 0.0006 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0061 0.0061
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0012 0.008
Schistosoma mansoni septate junction protein 0.0024 0.0009 0.003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0021 0.015
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0028 0.0039
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0064 0.0063 0.0063
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0031
Brugia malayi nuclear receptor NHR-88 0.0029 0.0016 0.0116
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0093 0.0102 0.0719
Brugia malayi Patched related family protein 12 0.0019 0.0002 0.0016
Brugia malayi hypothetical protein 0.0067 0.0066 0.0469
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0024 0.0009 0.0031
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Schistosoma mansoni ets 0.0021 0.0004 0.0016
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0006 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0045 0.0154
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.003 0.0237
Brugia malayi Myosin head containing protein 0.0019 0.0002 0.0016
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0364 0.0464 0.3278
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0074 0.0257
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0021 0.0021
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.0092 0.0643
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0178 0.0215 0.1861
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0102 0.0352
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0064 0.0063 0.0085
Brugia malayi Patched protein homolog 1 0.0019 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0022 0.0006 0.0006
Echinococcus granulosus microtubule associated protein 2 0.2178 0.2893 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0065 0.0064 0.0092
Schistosoma mansoni hypothetical protein 0.0115 0.0131 0.0453
Echinococcus granulosus tm gpcr rhodopsin 0.0093 0.0102 0.0352
Mycobacterium tuberculosis Possible oxidoreductase 0.0104 0.0116 0.0338
Loa Loa (eye worm) histone deacetylase 11 0.0442 0.0569 0.4022
Loa Loa (eye worm) hypothetical protein 0.0651 0.0849 0.5998
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0001 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0049 0.0403
Schistosoma mansoni histone deacetylase 0.087 0.1142 0.3949
Schistosoma mansoni DNA ligase IV 0.0067 0.0066 0.023
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0093 0.0102 0.0352
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0364 0.0464 0.3278
Echinococcus granulosus bloom syndrome protein 0.0022 0.0006 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0187 0.0227 0.0785
Toxoplasma gondii DNA ligase (NAD+), putative 0.0074 0.0076 0.011
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0038 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.007 0.0585
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0039 0.0321
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0316 0.2744
Echinococcus multilocularis GA binding protein alpha chain 0.0142 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.0198
Trichomonas vaginalis Sentrin-specific protease, putative 0.0091 0.0099 0.084
Schistosoma mansoni alpha-1 adrenergic receptor 0.0093 0.0102 0.0352
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0553 0.0717 0.5066
Schistosoma mansoni septate junction protein 0.0024 0.0009 0.003
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0055 0.005 0.0072
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0028 0.0069
Giardia lamblia Casein kinase II beta chain 0.0037 0.0027 0.0184
Plasmodium falciparum histone deacetylase, putative 0.1075 0.1416 0.2119
Mycobacterium ulcerans hypothetical protein 0.0024 0.0009 0.0005
Schistosoma mansoni opsin-like receptor 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Brugia malayi Niemann-Pick C1 protein precursor 0.0311 0.0393 0.2779
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Schistosoma mansoni ap endonuclease 0.004 0.003 0.0103
Entamoeba histolytica deoxycytidyl transferase, putative 0.0113 0.0129 0.1106
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.029 0.0365 0.2563
Schistosoma mansoni hypothetical protein 0.0504 0.0652 0.2254
Trypanosoma brucei histone deacetylase, putative 0.1075 0.1416 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0011 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0026 0.0011 0.0011
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0016 0.0116
Echinococcus multilocularis 0.0104 0.0116 0.0116
Schistosoma mansoni protein kinase subunit beta 0.0117 0.0133 0.0461
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0163 0.0195 0.058
Loa Loa (eye worm) hypothetical protein 0.0218 0.0269 0.1903
Trypanosoma brucei GMP reductase 0.0022 0.0006 0.0022
Schistosoma mansoni hypothetical protein 0.0115 0.0131 0.0453
Loa Loa (eye worm) hypothetical protein 0.0163 0.0195 0.1381
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0187 0.0227 0.1603
Echinococcus multilocularis tumor protein p63 0.1067 0.1405 0.1405
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0316 0.2744
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0039 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.008
Loa Loa (eye worm) IMP dehydrogenase 1 0.0022 0.0006 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0045 0.0365
Brugia malayi jmjC domain containing protein 0.0064 0.0063 0.0446
Trypanosoma cruzi histone deacetylase, putative 0.0442 0.0569 0.4016
Onchocerca volvulus 0.0117 0.0133 0.1992
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0011 0.0073
Trichomonas vaginalis histone deacetylase, putative 0.087 0.1142 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0028 0.0015 0.0104
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0026 0.0011 0.0079
Echinococcus granulosus tyrosine protein kinase otk 0.0024 0.0009 0.003
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Loa Loa (eye worm) CXXC zinc finger family protein 0.0117 0.0133 0.094
Brugia malayi Carboxylesterase family protein 0.0091 0.0099 0.0702
Schistosoma mansoni jumonji domain containing protein 0.0064 0.0063 0.0218
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0136 0.0471
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.082 0.1075 0.1603
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0026 0.0011 0.0079
Echinococcus granulosus H:Cl exchange transporter 3 0.0022 0.0006 0.0021
Echinococcus multilocularis BC026374 protein (S09 family) 0.0091 0.0099 0.0099
Entamoeba histolytica cell division protein kinase 2, putative 0.005 0.0045 0.0365
Schistosoma mansoni biogenic amine receptor 0.0093 0.0102 0.0352
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.003 0.0201
Schistosoma mansoni hypothetical protein 0.0092 0.0101 0.0348
Schistosoma mansoni histone deacetylase 4 5 0.1075 0.1416 0.4893
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0476 0.0614 0.2122
Echinococcus granulosus caspase 8 0.0026 0.0012 0.0042
Brugia malayi Ets-domain containing protein 0.0142 0.0167 0.1177
Giardia lamblia Kinase, CAMK CAMKL 0.0051 0.0045 0.0344
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0022 0.0006 0.0021
Trypanosoma brucei cdc2-related kinase 3 0.005 0.0045 0.0295
Brugia malayi Steroid receptor seven-up type 2 0.0063 0.0061 0.0429
Onchocerca volvulus 0.0218 0.0269 0.4032
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni BC026374 protein (S09 family) 0.0091 0.0099 0.0343
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0037 0.0027 0.017
Brugia malayi jmjC domain containing protein 0.0071 0.0072 0.0509
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0016 0.0116
Schistosoma mansoni hypothetical protein 0.0091 0.0098 0.034
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0091 0.0099 0.0341
Plasmodium falciparum protein kinase 5 0.005 0.0045 0.0063
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0042
Echinococcus granulosus neuroglian 0.0024 0.0009 0.003
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0093 0.0102 0.0352
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0061 0.0429
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0001 0.0004
Echinococcus multilocularis flap endonuclease 1 0.0055 0.005 0.005
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0024 0.015
Echinococcus granulosus ewsr:fli fusion protein type 0.0021 0.0004 0.0016
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Toxoplasma gondii NEK kinase 0.0023 0.0007 0.0008
Schistosoma mansoni elf1 0.0021 0.0004 0.0016
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0016 0.0116
Onchocerca volvulus 0.0093 0.0102 0.1523
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0093 0.0102 0.0352
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0063 0.0061 0.0429
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0063 0.0085
Toxoplasma gondii zinc finger cdgsh type protein 0.0029 0.0015 0.002
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0178 0.0215 0.0215
Chlamydia trachomatis deubiquitinase/deneddylase Dub1 0.0038 0.0028 0.0033
Loa Loa (eye worm) hypothetical protein 0.0104 0.0116 0.082
Echinococcus granulosus histone deacetylase 6 0.1075 0.1416 0.4893
Trypanosoma brucei metacaspase MCA2 0.0026 0.0012 0.0065
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0023 0.0007 0.004
Onchocerca volvulus 0.0091 0.0099 0.1486
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0644 0.084 0.1256
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0061 0.021
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Plasmodium falciparum protoporphyrinogen oxidase 0.0104 0.0116 0.0171
Loa Loa (eye worm) hypothetical protein 0.0141 0.0166 0.1174
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0275 0.0346 0.1194
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0063 0.0085
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0017 0.006
Echinococcus granulosus Mastin 0.0024 0.0009 0.0031
Echinococcus multilocularis hemicentin 1 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Loa Loa (eye worm) neuropeptide F receptor 0.0093 0.0102 0.0719
Schistosoma mansoni adenoreceptor 0.0093 0.0102 0.0352
Brugia malayi hypothetical protein 0.0093 0.0102 0.0719
Schistosoma mansoni biogenic amine (5HT) receptor 0.0093 0.0102 0.0352
Brugia malayi hypothetical protein 0.0019 0.0002 0.0016
Echinococcus granulosus Protein patched homolog 1 0.0133 0.0156 0.0538
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0009 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0154 0.0184 0.0544
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0064 0.0063 0.0175
Giardia lamblia Histone deacetylase 0.087 0.1142 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0093 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0076 0.0079 0.0557
Giardia lamblia Kinase, NEK 0.0023 0.0007 0.0013
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0024 0.015
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0006 0.0027
Brugia malayi hypothetical protein 0.0038 0.0028 0.02
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0012 0.0083
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Echinococcus multilocularis neuroligin 0.0091 0.0099 0.0099
Onchocerca volvulus 0.0029 0.0016 0.0247
Loa Loa (eye worm) hypothetical protein 0.0064 0.0063 0.0444
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Echinococcus granulosus intestinal type alkaline phosphatase 0.0178 0.0215 0.0744
Echinococcus multilocularis serine:threonine protein kinase Nek1 0.0018 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0187 0.0227 0.0785
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0086 0.0092 0.0643
Leishmania major DNA polymerase eta, putative 0.0141 0.0166 0.1156
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0063 0.0061 0.021
Trichomonas vaginalis histone deacetylase, putative 0.087 0.1142 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0187 0.0227 0.0785
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.0083
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0047 0.031
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0102 0.0352
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0218 0.0269 0.0805
Echinococcus multilocularis sterol regulatory element binding protein 0.0133 0.0156 0.0156
Brugia malayi AMP-binding enzyme family protein 0.0218 0.0269 0.1903
Giardia lamblia Sentrin specific protease, putative 0.0038 0.0028 0.0194
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0016 0.0116
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0104 0.0116 0.0401
Onchocerca volvulus Protein patched homolog 0.0019 0.0002 0.0034
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.002 0.0027
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0054 0.0049 0.0169
Onchocerca volvulus 0.0499 0.0644 0.9647
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0066 0.046
Brugia malayi hypothetical protein 0.0034 0.0022 0.0155
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0091 0.0099 0.0287
Trypanosoma cruzi cdc2-related kinase 3 0.005 0.0045 0.0305
Loa Loa (eye worm) hypothetical protein 0.0091 0.0099 0.0702
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0064 0.0063 0.0175
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0016 0.0057
Echinococcus granulosus muscleblind protein 0.0623 0.0811 0.2802
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Treponema pallidum DNA ligase (lig) 0.0208 0.0255 0.4375
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0026 0.0011 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0063 0.0061 0.0429
Loa Loa (eye worm) hypothetical protein 0.0165 0.0198 0.1401
Echinococcus granulosus contactin 0.0024 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Brugia malayi CXXC zinc finger family protein 0.0117 0.0133 0.094
Loa Loa (eye worm) hypothetical protein 0.0063 0.0061 0.0429
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0056 0.0081
Echinococcus granulosus sterol regulatory element binding protein 0.0133 0.0156 0.0538
Plasmodium falciparum histone deacetylase 2 0.1075 0.1416 0.2119
Loa Loa (eye worm) neuropeptide F receptor 0.0093 0.0102 0.0719
Brugia malayi 6-phosphofructokinase 0.0119 0.0136 0.0963
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0178 0.0215 0.0215
Onchocerca volvulus Alicorn homolog 0.0102 0.0113 0.1699
Brugia malayi glutathione reductase 0.0038 0.0028 0.0199
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0249 0.031 0.031
Brugia malayi AMP-binding enzyme family protein 0.0218 0.0269 0.1903
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0028 0.0198
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0012 0.0015
Schistosoma mansoni caspase-7 (C14 family) 0.0098 0.0108 0.0373
Trypanosoma cruzi histone deacetylase, putative 0.1075 0.1416 1
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0251 0.0313 0.0938
Echinococcus granulosus cyclin dependent kinase 1 0.005 0.0045 0.0154
Brugia malayi histone deacetylase 3 (HD3) 0.087 0.1142 0.807
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.003 0.0036
Echinococcus granulosus histone deacetylase 1 0.087 0.1142 0.3949
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0093 0.0102 0.0102
Brugia malayi Histone deacetylase family protein 0.1075 0.1416 1
Onchocerca volvulus 0.0024 0.0009 0.0136
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0061 0.0429
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0047 0.0067
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0136 0.117
Plasmodium falciparum histone deacetylase 1 0.087 0.1142 0.1709
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0117 0.0133 0.0932
Onchocerca volvulus 0.0457 0.0589 0.8817
Loa Loa (eye worm) TK protein kinase 0.0018 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Echinococcus granulosus geminin 0.0515 0.0666 0.2302
Toxoplasma gondii hypothetical protein 0.0099 0.0109 0.016
Trichomonas vaginalis AGC family protein kinase 0.0178 0.0215 0.1861
Loa Loa (eye worm) hypothetical protein 0.0063 0.0061 0.0429
Brugia malayi Csnk2b protein 0.0037 0.0027 0.019
Echinococcus multilocularis cyclin dependent kinase 5 0.005 0.0045 0.0045
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0149 0.0514
Toxoplasma gondii propionate-CoA ligase 0.0064 0.0063 0.0091
Echinococcus granulosus somatostatin receptor 0.0093 0.0102 0.0352
Loa Loa (eye worm) histone deacetylase 3 0.087 0.1142 0.807
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0027 0.0211
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0022 0.0006 0.0042
Echinococcus granulosus neuropeptide Y receptor 0.0093 0.0102 0.0352
Trypanosoma brucei DNA polymerase kappa, putative 0.017 0.0205 0.1428
Loa Loa (eye worm) hypothetical protein 0.0091 0.0099 0.0702
Schistosoma mansoni hypothetical protein 0.0093 0.0102 0.0352
Entamoeba histolytica serine/threonine protein kinase, putative 0.0051 0.0045 0.037
Leishmania major hypothetical protein, conserved 0.0022 0.0006 0.0024
Schistosoma mansoni 3-dehydroquinate synthase 0.0251 0.0313 0.1082
Echinococcus multilocularis Protein lozenge 0.0057 0.0054 0.0054
Chlamydia trachomatis dehyroquinate synthase 0.0251 0.0313 0.046
Plasmodium falciparum protein MAM3, putative 0.0022 0.0006 0.0006
Schistosoma mansoni gliotactin 0.0091 0.0099 0.0343
Onchocerca volvulus 0.0093 0.0102 0.1523
Schistosoma mansoni neuropeptide receptor 0.0093 0.0102 0.0352
Mycobacterium ulcerans carboxylesterase, LipT 0.0091 0.0099 0.014
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.005 0.0045 0.0063
Loa Loa (eye worm) hypothetical protein 0.0077 0.008 0.0562
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0023 0.0007 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0011 0.0073
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0022 0.0006 0.0016
Trypanosoma cruzi DNA polymerase eta, putative 0.0141 0.0166 0.1165
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0066 0.0558
Mycobacterium ulcerans oxidoreductase 0.0104 0.0116 0.0165
Trichomonas vaginalis histone deacetylase, putative 0.087 0.1142 1
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0034 0.0249
Trypanosoma brucei SUMO1/Ulp2, putative 0.0038 0.0028 0.0178
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0029 0.01
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0091 0.0099 0.0343
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0061
Chlamydia trachomatis deubiquitinase/deneddylase Dub2 0.0038 0.0028 0.0033
Echinococcus multilocularis hemicentin 1 0.0024 0.0009 0.0009
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0023 0.0007 0.0043
Onchocerca volvulus 0.0029 0.0015 0.023
Toxoplasma gondii PfMNL-2 CISD1 family iron-sulfur protein, putative 0.0029 0.0015 0.002
Brugia malayi RNA binding protein 0.0128 0.0149 0.1051
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0027 0.0211
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0093 0.0102 0.0352
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0447 0.0576 0.5026
Echinococcus granulosus enteropeptidase 0.0024 0.0009 0.0031
Loa Loa (eye worm) runx1 0.0057 0.0054 0.038
Loa Loa (eye worm) AUR protein kinase 0.0178 0.0215 0.1519
Trypanosoma brucei DNA polymerase kappa, putative 0.017 0.0205 0.1428
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0159 0.0189 0.0189
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0094 0.0269
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0102 0.0352
Echinococcus multilocularis ecdysone induced protein 78C 0.0063 0.0061 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0102 0.0102
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.003 0.0191
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0047 0.0039 0.032
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0016 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0061 0.021
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0093 0.0102 0.0352
Echinococcus multilocularis dual specificity 0.0198 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0109
Toxoplasma gondii aurora kinase 0.0178 0.0215 0.0319
Plasmodium falciparum sentrin-specific protease 1 0.0038 0.0028 0.0039
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0067 0.0066 0.0558
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0394 0.0504 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0069 0.007 0.0492
Loa Loa (eye worm) hypothetical protein 0.0091 0.0098 0.0694
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0003 0.0011
Brugia malayi hypothetical protein 0.0019 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0116
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0026 0.0011 0.0013
Echinococcus granulosus FTZ F1 alpha 0.0063 0.0061 0.021
Brugia malayi follicle stimulating hormone receptor 0.0093 0.0102 0.0719
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0024 0.0083
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0251 0.0313 0.0939
Schistosoma mansoni hypothetical protein 0.0115 0.0131 0.0453
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0068 0.0067 0.0467
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.024 0.0299 0.0299
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0178 0.0215 0.1861
Loa Loa (eye worm) hypothetical protein 0.0064 0.0063 0.0444
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0055 0.0051 0.0139
Plasmodium falciparum glutathione reductase 0.0038 0.0028 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.008
Brugia malayi MH2 domain containing protein 0.0252 0.0315 0.2222
Loa Loa (eye worm) hypothetical protein 0.0091 0.0099 0.0702
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0218 0.0269 0.0395
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0065 0.0064 0.044
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0012 0.008
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0064 0.0063 0.0175
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0037 0.0027 0.017
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0026 0.0012 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0063 0.0061 0.0429
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0017 0.006
Loa Loa (eye worm) D-ets-2 protein 0.0021 0.0004 0.0032
Chlamydia trachomatis protoporphyrinogen oxidase 0.0104 0.0116 0.0165
Brugia malayi nuclear hormone receptor 0.0063 0.0061 0.0429
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0077 0.008 0.0562
Schistosoma mansoni hypothetical protein 0.0093 0.0102 0.0352
Echinococcus granulosus casein kinase ii subunit beta 0.0037 0.0027 0.0093
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0006 0.0021
Brugia malayi ecdysone receptor 0.0029 0.0016 0.0116
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0064 0.0063 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0102 0.0102
Onchocerca volvulus 0.0091 0.0099 0.1486
Brugia malayi Patched related family protein 10 0.0019 0.0002 0.0016
Onchocerca volvulus 0.0093 0.0102 0.1523
Echinococcus multilocularis lachesin 0.0024 0.0009 0.0009
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0093 0.0102 0.1523
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0061
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0136 0.0471
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0038 0.0028 0.0178
Brugia malayi Calcitonin receptor-like protein seb-1 0.0364 0.0464 0.3278
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0069 0.007 0.0492
Echinococcus granulosus ETS transcription factor Elf 5 0.0021 0.0004 0.0016
Echinococcus multilocularis muscleblind protein 0.0623 0.0811 0.0811
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0316 0.04 0.1382
Brugia malayi Amyloid A4 extracellular domain containing protein 0.036 0.0459 0.3242
Brugia malayi Ets-domain containing protein 0.0142 0.0167 0.1177
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0012 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0045 0.037
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0061 0.021
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0064 0.0063 0.0085
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.02
Brugia malayi GnHR receptor homolog 0.0093 0.0102 0.0719
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0091 0.0098 0.034
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0276
Brugia malayi ancient conserved domain protein 4 0.0022 0.0006 0.0042
Echinococcus granulosus 7tm_1 domain containing protein 0.0093 0.0102 0.0352
Loa Loa (eye worm) hypothetical protein 0.0067 0.0066 0.0469
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0009 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0012 0.0083
Schistosoma mansoni hypothetical protein 0.0515 0.0666 0.2302
Echinococcus multilocularis Immunoglobulin 0.0038 0.0028 0.0028
Echinococcus granulosus caspase 0.0098 0.0108 0.0373
Loa Loa (eye worm) acetyltransferase 0.0159 0.0189 0.1337
Brugia malayi Patched family protein 0.0019 0.0002 0.0016
Entamoeba histolytica hypothetical protein 0.0071 0.0072 0.061
Echinococcus granulosus allatostatin A receptor 0.0093 0.0102 0.0352
Plasmodium falciparum glycogen synthase kinase 3 0.0054 0.0049 0.007
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0063 0.0061 0.0429
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Trypanosoma cruzi chloride channel protein, putative 0.0022 0.0006 0.0032
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0022 0.0006 0.0032
Toxoplasma gondii HEAT repeat-containing protein 0.0088 0.0095 0.0139
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0006 0.0027
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Loa Loa (eye worm) carboxylesterase 0.0091 0.0099 0.0702
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.002 0.0246
Entamoeba histolytica serine/threonine protein kinase, putative 0.0023 0.0007 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.017 0.0205 0.1428
Schistosoma mansoni steroid hormone receptor ad4bp 0.0063 0.0061 0.021
Brugia malayi Carboxylesterase family protein 0.0541 0.0701 0.4951
Echinococcus multilocularis dna polymerase kappa 0.017 0.0205 0.0205
Brugia malayi topoisomerase 0.0067 0.0066 0.0469
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0061
Trypanosoma brucei unspecified product 0.0078 0.0082 0.0558
Echinococcus granulosus g protein coupled receptor 0.0093 0.0102 0.0352
Treponema pallidum fructose-bisphosphate aldolase 0.0447 0.0576 1
Trichomonas vaginalis rotamase, putative 0.0068 0.0067 0.0566
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Onchocerca volvulus 0.0019 0.0002 0.0034
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0063 0.0444
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0045 0.0045
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0104 0.0116 0.0171
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.003 0.0211
Echinococcus granulosus alkaline phosphatase 0.0178 0.0215 0.0744
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0003 0.0001
Echinococcus granulosus biogenic amine 5HT receptor 0.0093 0.0102 0.0352
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0093 0.0102 0.0352
Onchocerca volvulus 0.0156 0.0186 0.2784
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0023 0.0007 0.0043
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0093 0.0102 0.0352
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0187 0.0227 0.0227
Schistosoma mansoni opsin-like receptor 0.0093 0.0102 0.0352
Echinococcus multilocularis ewsr:fli fusion protein type 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0093 0.0102 0.1523
Brugia malayi nuclear hormone receptor 0.0029 0.0016 0.0116
Loa Loa (eye worm) hypothetical protein 0.0038 0.0028 0.02
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.002 0.015
Toxoplasma gondii histone lysine-specific demethylase 0.0104 0.0116 0.0171
Brugia malayi ecdysteroid receptor 0.0063 0.0061 0.0429
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0154 0.0184 0.0544
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0219 0.027 0.027
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0016 0.0116
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0063 0.0434
Leishmania major mitochondrial DNA polymerase beta 0.0612 0.0797 0.562
Echinococcus granulosus g-protein coupled receptor 0.0093 0.0102 0.0352
Brugia malayi 6-phosphofructokinase 0.0119 0.0136 0.0962
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0024 0.0009 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0101 0.0691
Loa Loa (eye worm) hypothetical protein 0.0067 0.0066 0.0469
Echinococcus multilocularis AMPK beta subunit 0.0117 0.0133 0.0133
Brugia malayi histone deacetylase 11 0.0442 0.0569 0.4022
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0364 0.0464 0.3278
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0008 0.0029
Brugia malayi ancient conserved domain protein 2 0.0022 0.0006 0.0042
Onchocerca volvulus 0.0064 0.0063 0.094
Brugia malayi Muscleblind-like protein 0.0623 0.0811 0.5727
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0067 0.0066 0.0469
Plasmodium vivax hypothetical protein, conserved 0.0104 0.0116 0.0171
Schistosoma mansoni cpg binding protein 0.0123 0.0142 0.0491
Brugia malayi hypothetical protein 0.0033 0.0021 0.015
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0093 0.0102 0.0102
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0117 0.0133 0.0941
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0117 0.0133 0.112
Onchocerca volvulus 0.0093 0.0102 0.1523
Plasmodium vivax acetyl-CoA synthetase, putative 0.0064 0.0063 0.0091
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0182 0.0221 0.3308
Echinococcus granulosus orexin receptor type 2 0.0093 0.0102 0.0352
Brugia malayi AKH receptor 0.0093 0.0102 0.0719
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0063 0.0175
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0047 0.0067
Echinococcus granulosus dna polymerase eta 0.0141 0.0166 0.0574
Brugia malayi Helix-hairpin-helix motif family protein 0.0021 0.0005 0.0038
Brugia malayi amine oxidase, flavin-containing family protein 0.0104 0.0116 0.082
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0111 0.0126 0.0185
Plasmodium vivax glycogen synthase kinase 3, putative 0.0054 0.0049 0.007
Onchocerca volvulus 0.0019 0.0002 0.0034
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0027 0.018
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.003 0.0041
Trypanosoma brucei importin beta-1 subunit, putative 0.0088 0.0095 0.0649
Onchocerca volvulus 0.0063 0.0061 0.0908
Echinococcus granulosus neuropeptide Y receptor 0.0093 0.0102 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0012 0.008
Loa Loa (eye worm) hypothetical protein 0.0104 0.0116 0.082
Echinococcus granulosus ubiquitin specific protease 41 0.0077 0.008 0.0275
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0028 0.0221
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0028 0.0221
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0065 0.0064 0.0449
Trypanosoma cruzi FHA domain containing protein, putative 0.0067 0.0066 0.046
Brugia malayi hypothetical protein 0.0024 0.0009 0.0064
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0394 0.0504 0.0747
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0054 0.0049 0.0049
Plasmodium falciparum DNA repair protein REV1, putative 0.0035 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.0093 0.0102 0.0719

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) = 1.53 uM Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 mins ChEMBL. 23621789
ED50 (functional) = 0.41 mg kg-1 In vivo cannabinergic activity of the compound was determined in rat after 90 min of dose administration (0.03-1.8 mg/kg) using drug discrimination assay ChEMBL. 15999995
ED50 (functional) = 0.44 mg kg-1 In vivo cannabinergic activity of the compound was determined in rat after 90 min of dose administration (0.03-1.8 mg/kg) using drug discrimination assay ChEMBL. 15999995
ED50 (functional) = 0.68 mg kg-1 In vivo cannabinergic activity of the compound was determined in rat after 30 min of dose administration (0.03-1.8 mg/kg) using drug discrimination assay ChEMBL. 15999995
Ki (binding) Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membranes ChEMBL. 20593789
Ki (binding) = 1.72 Displacement of [3H]CP 55940 from human CB2 receptor in cell free system ChEMBL. 21183257
Ki (binding) = 6.8 nM Inhibition of [3H]CP-55,940 binding to cannabinoid receptor 1 of rat brain ChEMBL. 15999995
Ki (binding) = 6.8 nM Displacement of [3H]CP-55,940 from rat brain CB1 receptor ChEMBL. 16387492
Ki (binding) = 6.8 nM Binding affinity to CB1 receptor (unknown origin) ChEMBL. 17521177
Ki (binding) = 6.8 nM Inhibition of [3H]CP-55,940 binding to cannabinoid receptor 1 of rat brain ChEMBL. 15999995
Ki (binding) = 6.8 nM Displacement of [3H]CP-55,940 from rat brain CB1 receptor ChEMBL. 16387492
Ki (binding) = 6.8 nM Binding affinity to CB1 receptor (unknown origin) ChEMBL. 17521177
Ki (binding) = 6.8 nM Displacement of [3H]CP-55940 from CB1 receptor in rat brain synaptosome membrane ChEMBL. 18826296
Ki (binding) = 6.8 nM Binding affinity to CB1 receptor ChEMBL. 19250829
Ki (binding) = 6.8 nM Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay ChEMBL. 23621789
Ki (binding) = 52 nM Inhibition of [3H]CP-55,940 binding to cannabinoid receptor 2 of mouse spleen membranes ChEMBL. 15999995
Ki (binding) = 52 nM Displacement of [3H]CP-55,940 from mouse spleen CB2 receptor ChEMBL. 16387492
Ki (binding) = 52 nM Binding affinity to CB2 receptor (unknown origin) ChEMBL. 17521177
Ki (binding) = 52 nM Inhibition of [3H]CP-55,940 binding to cannabinoid receptor 2 of mouse spleen membranes ChEMBL. 15999995
Ki (binding) = 52 nM Displacement of [3H]CP-55,940 from mouse spleen CB2 receptor ChEMBL. 16387492
Ki (binding) = 52 nM Binding affinity to CB2 receptor (unknown origin) ChEMBL. 17521177
Ki (binding) = 52 nM Displacement of [3H]CP-55940 from CB2 receptor in mouse spleen membrane ChEMBL. 18826296
Ki (binding) = 52 nM Binding affinity to CB2 receptor ChEMBL. 19250829
Ki (binding) = 52 nM Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay ChEMBL. 23621789
Ki (binding) = 0.0068 uM Displacement of [3H]CP-55940 from CB1 receptor in rat brain ChEMBL. 20593789
Ki (binding) = 0.052 uM Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in HEK293 cell membranes ChEMBL. 20593789
Ratio (binding) = 0.62 Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 mins relative to WIN55,212-2 ChEMBL. 23621789
Ratio Ki (binding) = 0.1 Selectivity for rat CB1 receptor over mouse CB2 receptor ChEMBL. 16387492

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

8 literature references were collected for this gene.

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