Detailed information for compound 510400

Basic information

Technical information
  • TDR Targets ID: 510400
  • Name: N-benzyl-6-(furan-2-yl)-2-methoxypurine-9-car boxamide
  • MW: 349.343 | Formula: C18H15N5O3
  • H donors: 1 H acceptors: 4 LogP: 2.32 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1nc(c2ccco2)c2c(n1)n(cn2)C(=O)NCc1ccccc1
  • InChi: 1S/C18H15N5O3/c1-25-17-21-14(13-8-5-9-26-13)15-16(22-17)23(11-20-15)18(24)19-10-12-6-3-2-4-7-12/h2-9,11H,10H2,1H3,(H,19,24)
  • InChiKey: JREWZOTXARJEGR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-benzyl-6-(2-furyl)-2-methoxy-purine-9-carboxamide
  • N-benzyl-6-(2-furyl)-2-methoxy-9-purinecarboxamide
  • 6-(furan-2-yl)-2-methoxy-N-(phenylmethyl)purine-9-carboxamide
  • 6-furan-2-yl-2-methoxy-N-(phenylmethyl)purine-9-carboxamide
  • 6-(2-furyl)-2-methoxy-N-(phenylmethyl)purine-9-carboxamide
  • 6-(2-furyl)-2-methoxy-N-(phenylmethyl)-9-purinecarboxamide
  • N-(benzyl)-6-(2-furyl)-2-methoxy-purine-9-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adenosine A1 receptor Starlite/ChEMBL References
Homo sapiens adenosine A2a receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi follicle stimulating hormone receptor adenosine A2a receptor 412 aa 336 aa 22.3 %
Brugia malayi hypothetical protein adenosine A1 receptor 326 aa 305 aa 21.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Echinococcus multilocularis geminin 0.0336 0.237 0.2368
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0056
Brugia malayi 6-phosphofructokinase 0.0112 0.0757 0.253
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0171 0.0401
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0289 0.2032 1
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0008 0.001 0.0008
Leishmania major hypothetical protein, conserved 0.0008 0.001 0.0096
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0757 0.1796
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0024 0.0052
Echinococcus granulosus Sugar transporter ERD6 protein 0.001 0.0024 0.0022
Onchocerca volvulus 0.0083 0.0549 0.1607
Onchocerca volvulus 0.001 0.0024 0.0064
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.001 0.0039
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0024 0.0022
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.001 0.0019
Leishmania major hypothetical protein, conserved 0.0008 0.001 0.0096
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.001 0.0008
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Treponema pallidum fructose-bisphosphate aldolase 0.0591 0.4209 1
Onchocerca volvulus 0.0008 0.001 0.0023
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0121 0.1438
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0794 0.5672 0.5671
Echinococcus granulosus synaptic vesicle 2 protein 0.001 0.0024 0.0022
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.029 0.0288
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0372 0.037
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0757 1
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0008 0.001 0.0105
Trypanosoma cruzi hexose transporter, putative 0.001 0.0024 0.029
Loa Loa (eye worm) oxidoreductase 0.0008 0.001 0.0027
Leishmania major short chain dehydrogenase, putative 0.0008 0.001 0.0096
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0008 0.001 0.0667
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.001 0.0039
Toxoplasma gondii carbonyl reductase 1, putative 0.0008 0.001 0.0096
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0831 0.0829
Trypanosoma brucei glucose transporter, putative 0.001 0.0024 0.029
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0024 0.029
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.001 0.0019
Onchocerca volvulus 0.0008 0.001 0.0023
Echinococcus granulosus solute carrier family 22 0.001 0.0024 0.0022
Leishmania major dehydrogenase-like protein 0.0008 0.001 0.0096
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0008 0.001 0.0019
Onchocerca volvulus 0.0008 0.001 0.0023
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0184 0.1279 0.1278
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0034 0.0109
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.001 0.0105
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0757 0.1796
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Brugia malayi Dehydrogenases, short chain protein 30 0.0008 0.001 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0695 0.0695
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0019 0.0056
Trypanosoma brucei glucose transporter, putative 0.001 0.0024 0.029
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0134 0.6401
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0171 0.0402
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Echinococcus granulosus lamin 0.0027 0.0147 0.0145
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0002 0.000000000063838
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0204 0.0481
Schistosoma mansoni apoferritin-2 0.0008 0.0013 0.0013
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.001 0.0105
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0111 0.011
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.001 0.0039
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0008 0.001 0.0096
Brugia malayi hypothetical protein 0.0025 0.0134 0.0443
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.001 0.0008
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0591 0.4209 1
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0008 0.001 0.0105
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0008 0.001 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Schistosoma mansoni glucose transport protein 0.001 0.0024 0.0024
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.001 0.0019
Leishmania major hypothetical protein, conserved 0.0008 0.001 0.0096
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0204 0.048
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0008 0.001 0.0105
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0289 0.2032 1
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0757 0.0757
Entamoeba histolytica short chain dehydrogenase family protein 0.0008 0.001 0.0019
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0008 0.001 0.0105
Onchocerca volvulus 0.001 0.0024 0.0064
Brugia malayi hypothetical protein 0.0016 0.007 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0079 0.026
Giardia lamblia Short-chain dehydrogenase, putative 0.0008 0.001 0.0019
Echinococcus granulosus solute carrier family 22 0.001 0.0024 0.0022
Brugia malayi CXXC zinc finger family protein 0.0029 0.0166 0.055
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.001 0.0023
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0147 0.0485
Schistosoma mansoni cpg binding protein 0.0031 0.0178 0.0178
Brugia malayi Pre-SET motif family protein 0.0061 0.0393 0.1309
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.001 0.0008
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.001 0.0105
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0103 0.0695 0.8365
Loa Loa (eye worm) oxidoreductase 0.0008 0.001 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0171 0.0402
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Brugia malayi mbt repeat family protein 0.0047 0.029 0.0965
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0008 0.001 0.0105
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.001 0.0019
Onchocerca volvulus 0.001 0.0024 0.0064
Onchocerca volvulus 0.0061 0.0393 0.1148
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Onchocerca volvulus 0.0008 0.001 0.0023
Echinococcus multilocularis mitogen activated protein kinase 3 0.0103 0.0695 0.0694
Echinococcus granulosus geminin 0.0336 0.237 0.2368
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0024 0.0022
Giardia lamblia Kinase, CMGC MAPK 0.0103 0.0695 0.1648
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0103 0.0695 0.9179
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0591 0.4209 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Giardia lamblia Hexose transporter 0.001 0.0024 0.0052
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0171 0.2037
Trypanosoma brucei glucose transporter, putative 0.001 0.0024 0.029
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0103 0.0695 0.9179
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0204 0.0481
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0022 0.002
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0337 0.0337
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0038 0.0086
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Echinococcus granulosus lamin dm0 0.0027 0.0147 0.0145
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0337 0.1121
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0008 0.001 0.0105
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0008 0.001 0.0019
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0116 0.0789 0.0787
Echinococcus granulosus mitogen activated protein kinase 0.0103 0.0695 0.0694
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0757 0.1796
Schistosoma mansoni transcription factor btf3 0.0035 0.0204 0.0204
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0757 0.253
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0019 0.0203
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0171 0.0402
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0024 0.029
Mycobacterium ulcerans short-chain type oxidoreductase 0.0008 0.001 0.0039
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0171 0.8287
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Toxoplasma gondii facilitative glucose transporter GT1 0.001 0.0024 0.0264
Schistosoma mansoni ferritin 0.0008 0.0013 0.0013
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0024 0.0073
Mycobacterium ulcerans bacterioferritin BfrB 0.0008 0.0013 0.0057
Trichomonas vaginalis myo-inositol transporter, putative 0.001 0.0024 0.0052
Echinococcus multilocularis cpg binding protein 0.0031 0.0178 0.0176
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0008 0.001 0.0019
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.001 0.0008
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.001 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0043 0.0139
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0022 0.002
Brugia malayi MAP kinase sur-1 0.0103 0.0695 0.2322
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0591 0.4209 1
Trypanosoma brucei glucose transporter 2A 0.001 0.0024 0.029
Trichomonas vaginalis glucose transporter, putative 0.001 0.0024 0.0052
Leishmania major short chain dehydrogenase, putative 0.0008 0.001 0.0096
Schistosoma mansoni hypothetical protein 0.001 0.0024 0.0024
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0078 0.0078
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0008 0.001 0.0096
Loa Loa (eye worm) oxidoreductase 0.0008 0.001 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0591 0.4209 1
Schistosoma mansoni carbonyl reductase 0.0008 0.001 0.001
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0204 1
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0008 0.001 0.0039
Loa Loa (eye worm) oxidoreductase 0.0008 0.001 0.0027
Schistosoma mansoni hypothetical protein 0.0007 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Echinococcus granulosus carbonyl reductase 1 0.0008 0.001 0.0008
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0045 0.0565
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.001 0.0024 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.001 0.0105
Schistosoma mansoni lamin 0.0027 0.0147 0.0147
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.029 0.0288
Schistosoma mansoni DNA helicase recq5 0.0009 0.0019 0.0019
Onchocerca volvulus 0.0008 0.001 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0121 0.1578
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0024 0.0022
Brugia malayi Dehydrogenases, short chain protein 2 0.0008 0.001 0.0027
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0284 0.1998 0.1998
Schistosoma mansoni ferritin light chain 0.0008 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.001 0.0105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0002 0.000000000063838
Entamoeba histolytica hypothetical protein 0.0023 0.0121 0.0283
Trichomonas vaginalis ferritin, putative 0.0008 0.0013 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0591 0.4209 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Onchocerca volvulus 0.0008 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0116 0.0789 0.3876
Echinococcus multilocularis expressed protein 0.0008 0.0013 0.0012
Mycobacterium tuberculosis Probable dehydrogenase 0.0008 0.001 0.0039
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0008 0.0013 0.0057
Echinococcus multilocularis microtubule associated protein 2 0.1395 1 1
Trypanosoma cruzi short chain dehydrogenase, putative 0.0008 0.001 0.0105
Schistosoma mansoni sugar transporter 0.001 0.0024 0.0024
Schistosoma mansoni lamin 0.0027 0.0147 0.0147
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0024 0.0073
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0096
Leishmania major hypothetical protein, conserved 0.0008 0.001 0.0096
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0103 0.0695 0.9179
Loa Loa (eye worm) sugar transporter 0.001 0.0024 0.0073
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0111 0.0261
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Echinococcus granulosus transcription factor btf3 0.0035 0.0204 0.0202
Onchocerca volvulus Putative transporter 0.001 0.0024 0.0064
Brugia malayi hypothetical protein 0.0008 0.001 0.0027
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Plasmodium vivax SET domain protein, putative 0.0061 0.0393 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0038 0.0477
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Schistosoma mansoni hypothetical protein 0.0336 0.237 0.237
Echinococcus multilocularis conserved hypothetical protein 0.0008 0.001 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0695 0.9179
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0171 0.2037
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0021 0.0249
Onchocerca volvulus 0.0479 0.3406 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0591 0.4209 1
Echinococcus multilocularis mitogen activated protein kinase 0.0103 0.0695 0.0694
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0695 0.1649
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.029 0.029
Trypanosoma cruzi glucose transporter, putative 0.001 0.0024 0.029
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0393 0.0391
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0831 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0008 0.001 0.0008
Onchocerca volvulus Sepiapterin reductase homolog 0.0008 0.001 0.0023
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0337 0.0335
Schistosoma mansoni intermediate filament proteins 0.0027 0.0147 0.0147
Onchocerca volvulus 0.001 0.0024 0.0064
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Brugia malayi dehydrogenases, short chain protein 2 0.0008 0.001 0.0027
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0831 0.4083
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0121 0.1438
Onchocerca volvulus 0.001 0.0024 0.0064
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0057 0.0185
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0171 0.0402
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.001 0.0096
Loa Loa (eye worm) hypothetical protein 0.0061 0.0393 0.1309
Brugia malayi Cytochrome P450 family protein 0.0013 0.0045 0.0143
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0171 0.4202
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0019 0.0203
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Echinococcus multilocularis solute carrier family 22 0.001 0.0024 0.0022
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0204 0.0677
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0045 0.0143
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0096
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0121 0.1438
Echinococcus granulosus expressed protein 0.0008 0.0013 0.0012
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0757 0.0757
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0116 0.0789 0.3876
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0757 0.1796
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0038 0.0435
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0116 0.0789 0.2636
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0019 0.0459
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0591 0.4209 1
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0008 0.001 0.0105
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0008 0.001 0.0105
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0035 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0393 0.0393
Trichomonas vaginalis set domain proteins, putative 0.0479 0.3406 0.8092
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0008 0.0013 0.0966
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0024 0.0022
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.001 0.0008
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.042 0.042
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0008 0.001 0.0039
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0337 0.0335
Schistosoma mansoni microtubule-associated protein tau 0.1395 1 1
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0096
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0757 0.0756
Trypanosoma brucei sugar transporter, putative 0.001 0.0024 0.029
Leishmania major myo-inositol/proton symporter (MIT) 0.001 0.0024 0.0264
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0108 0.0733 0.2447
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0008 0.001 0.0008
Echinococcus multilocularis solute carrier family 22 0.001 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0043 0.0139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0591 0.4209 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0092 0.4243
Schistosoma mansoni cpg binding protein 0.0029 0.0166 0.0166
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0121 0.2905
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0022 0.002
Echinococcus granulosus carbonyl reductase 1 0.0008 0.001 0.0008
Brugia malayi Sugar transporter family protein 0.001 0.0024 0.0073
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0008 0.001 0.0096
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Plasmodium vivax sugar transporter, putative 0.001 0.0024 0.0365
Mycobacterium leprae Probable oxidoreductase 0.0008 0.001 0.0039
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0116 0.0789 0.9493
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0008 0.001 0.0039
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0831 0.4083
Schistosoma mansoni sugar transporter 0.001 0.0024 0.0024
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0121 0.0587
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.001 0.0008
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0008 0.001 0.0105
Loa Loa (eye worm) MBCTL1 0.0053 0.0337 0.1121
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0393 0.0391
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0695 0.1649
Trypanosoma brucei protein kinase, putative 0.0103 0.0695 0.9179
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0008 0.001 0.0019
Schistosoma mansoni sugar transporter 0.001 0.0024 0.0024
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0757 0.0756
Echinococcus multilocularis ferritin 0.0008 0.0013 0.0012
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0007 0.0002 0.0002
Onchocerca volvulus 0.0008 0.001 0.0023
Echinococcus multilocularis retinol dehydrogenase 13 0.0008 0.001 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.001 0.0105
Leishmania major hypothetical protein, conserved 0.001 0.0024 0.0264
Onchocerca volvulus 0.001 0.0024 0.0064
Mycobacterium ulcerans oxidoreductase 0.0008 0.001 0.0039
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0121 1
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0134 0.1751
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.001 0.0008
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.001 0.0039
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.001 0.0023
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.001 0.0024 0.0024
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.001 0.0019
Echinococcus granulosus solute carrier family 22 0.001 0.0024 0.0022
Onchocerca volvulus 0.001 0.0024 0.0064
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.001 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0024 0.0052
Trichomonas vaginalis steroid dehydrogenase, putative 0.0008 0.001 0.0019
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.001 0.0024 0.029
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0008 0.001 0.0039
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0393 0.0393
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.001 0.0105
Leishmania major hypothetical protein, conserved 0.0025 0.0134 0.1595
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0008 0.001 0.0039
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0008 0.001 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0204 0.0481
Leishmania major short chain dehydrogenase/reductase, putative 0.0008 0.001 0.0096
Leishmania major hypothetical protein, conserved 0.0009 0.0021 0.0227
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0134 0.6401
Schistosoma mansoni carbonyl reductase 0.0008 0.001 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0045 0.0565
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.001 0.0096
Brugia malayi Pre-SET motif family protein 0.0421 0.2988 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0002 0.000000000063838
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0831 0.0831
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0007 0.0002 0.0002
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0008 0.001 0.001
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0008 0.001 0.0008
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.001 0.0039
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0022 0.002
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0038 0.0086
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0204 0.5071
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Onchocerca volvulus 0.0029 0.0166 0.0482
Onchocerca volvulus 0.001 0.0024 0.0064
Brugia malayi Sugar transporter family protein 0.001 0.0024 0.0073
Schistosoma mansoni ferritin 0.0008 0.0013 0.0013
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0111 0.0367
Trichomonas vaginalis glucose transporter, putative 0.001 0.0024 0.0052
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Onchocerca volvulus 0.001 0.0024 0.0064
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0008 0.001 0.0019
Brugia malayi hypothetical protein 0.0008 0.001 0.0027
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0008 0.001 0.0039
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0024 0.029
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0008 0.001 0.0105
Onchocerca volvulus 0.0008 0.001 0.0023
Leishmania major glucose transporter, lmgt2 0.001 0.0024 0.0264
Giardia lamblia Fructose-bisphosphate aldolase 0.0591 0.4209 1
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.001 0.0096
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0008 0.001 0.0019
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.029 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0024 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0024 0.0052
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0024 0.0022
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0019 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0204 0.2676
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Onchocerca volvulus 0.001 0.0024 0.0064
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0008 0.0013 0.0057
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.001 0.0024 0.1838
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0019 0.0017
Toxoplasma gondii oxidoreductase, putative 0.0008 0.001 0.0096
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0008 0.001 0.0039
Leishmania major basic transcription factor 3a, putative 0.0035 0.0204 0.2438
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0021 0.0249
Echinococcus multilocularis synaptic vesicle 2 protein 0.001 0.0024 0.0022
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0116 0.0789 0.0787
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0757 0.1796
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0008 0.001 0.0039
Entamoeba histolytica hypothetical protein 0.0035 0.0204 0.048
Mycobacterium ulcerans integral membrane transport protein 0.001 0.0024 0.0108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0002 0.000000000063838
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0008 0.001 0.0039
Brugia malayi beta-NAC-like protein 0.0035 0.0204 0.0677
Trypanosoma brucei glucose transporter, putative 0.001 0.0024 0.029
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Giardia lamblia Sugar-proton symporter 0.001 0.0024 0.0052
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0121 0.0587
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0096
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0757 1
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0011 0.0035 0.0035
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0045 0.0143
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Schistosoma mansoni cpg binding protein 0.0031 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Schistosoma mansoni carbonyl reductase 0.0008 0.001 0.001
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0103 0.0695 0.8365
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0019 0.0017
Brugia malayi phosphofructokinase 0.0112 0.0757 0.253
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.001 0.0024 0.0108
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.001 0.0039
Echinococcus multilocularis transcription factor btf3 0.0035 0.0204 0.0202
Onchocerca volvulus 0.001 0.0024 0.0064
Leishmania major cytochrome p450-like protein 0.0013 0.0045 0.0515
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0008 0.001 0.0105
Loa Loa (eye worm) oxidoreductase 0.0008 0.001 0.0027
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0289 0.2032 1
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0008 0.001 0.0023
Echinococcus granulosus oxidoreductase 0.0008 0.001 0.0008
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0024 0.0073
Echinococcus granulosus solute carrier family 22 0.001 0.0024 0.0022
Loa Loa (eye worm) oxidoreductase 0.0008 0.001 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0147 0.0485
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0019 0.004
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Brugia malayi intermediate filament protein 0.0027 0.0147 0.0485
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0013 0.0045 0.021
Trypanosoma cruzi hexose transporter 0.001 0.0024 0.029
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0008 0.001 0.0105
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0171 1
Mycobacterium ulcerans oxidoreductase 0.0008 0.001 0.0039
Brugia malayi major facilitator superfamily protein 0.001 0.0024 0.0073
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.001 0.0024 0.0719
Loa Loa (eye worm) hypothetical protein 0.0013 0.0047 0.0151
Trichomonas vaginalis glucose transporter, putative 0.001 0.0024 0.0052
Trypanosoma cruzi hexose transporter, putative 0.001 0.0024 0.029
Leishmania major pteridine reductase 1 0.0008 0.001 0.0096
Schistosoma mansoni sugar transporter 0.001 0.0024 0.0024
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0035 0.0033
Brugia malayi Retinol dehydrogenase 12 0.0008 0.001 0.0027
Onchocerca volvulus 0.0047 0.029 0.0846
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0372 0.4464
Loa Loa (eye worm) RecQ helicase 0.0022 0.0111 0.0367
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0831 0.0831
Onchocerca volvulus 0.0008 0.001 0.0023
Loa Loa (eye worm) POT family protein 0.0081 0.0538 0.1796
Echinococcus granulosus steroid dehydrogenase 0.0008 0.001 0.0008
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0695 0.9179
Schistosoma mansoni steroid dehydrogenase 0.0008 0.001 0.001
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0831 0.0829
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0757 0.3721
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0337 0.0335
Brugia malayi hypothetical protein 0.001 0.0024 0.0073
Loa Loa (eye worm) oxidoreductase 0.0008 0.001 0.0027
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0008 0.001 0.0019
Onchocerca volvulus 0.001 0.0024 0.0064
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.001 0.0096
Onchocerca volvulus 0.0008 0.001 0.0023
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0045 0.0143
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0757 0.9114
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0019 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0024 0.0052
Brugia malayi hypothetical protein 0.001 0.0024 0.0073
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0024 0.0073
Entamoeba histolytica short chain dehydrogenase family protein 0.0008 0.001 0.0019
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.006 0.1318
Onchocerca volvulus 0.001 0.0024 0.0064
Echinococcus multilocularis solute carrier family 22 0.001 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0695 0.1649
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.001 0.0024 0.0022
Schistosoma mansoni glucose transport protein 0.001 0.0024 0.0024
Schistosoma mansoni ferritin 0.0008 0.0013 0.0013
Entamoeba histolytica hypothetical protein, conserved 0.0008 0.001 0.0019
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0549 0.0547
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0008 0.001 0.001
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Toxoplasma gondii sugar transporter ST2 0.001 0.0024 0.0264
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.001 0.0019
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0008 0.001 0.0019
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Schistosoma mansoni glucose transporter 0.001 0.0024 0.0024
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0024 0.0073
Mycobacterium ulcerans sugar transporter 0.001 0.0024 0.0108
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0008 0.001 0.0039
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0204 0.2676
Trypanosoma brucei glucose transporter, putative 0.001 0.0024 0.029
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0008 0.001 0.0008
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0171 0.2037
Trypanosoma brucei oxidoreductase-like protein 0.0008 0.001 0.0105
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0184 0.1279 0.1278
Echinococcus granulosus WW domain containing oxidoreductase 0.0008 0.001 0.0008
Brugia malayi dehydrogenases, short chain protein 9 0.0008 0.001 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0002 0.000000000063838
Onchocerca volvulus 0.0027 0.0147 0.0426
Loa Loa (eye worm) hypothetical protein 0.0083 0.0549 0.1833
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0024 0.0052
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.001 0.0024 0.0108
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.029 0.029
Echinococcus granulosus hypothetical protein 0.0008 0.001 0.0008
Leishmania major glucose transporter, lmgt3 0.001 0.0024 0.0264
Echinococcus multilocularis lamin 0.0027 0.0147 0.0145
Toxoplasma gondii sugar transporter ST1 0.001 0.0024 0.0264
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0053 0.0337 0.1121
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0008 0.001 0.0039
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0171 0.4202
Leishmania major short chain dehydrogenase-like protein 0.0008 0.001 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0024 0.0052
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0008 0.001 0.0039
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0831 0.4083
Leishmania major glucose transporter/membrane transporter D2, putative 0.001 0.0024 0.0264
Loa Loa (eye worm) oxidoreductase 0.0008 0.001 0.0027
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0171 0.0401
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0171 1
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.001 0.0105
Giardia lamblia Hypothetical protein 0.0008 0.001 0.0019
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.001 0.0039
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.001 0.0096
Echinococcus multilocularis Sugar transporter ERD6 protein 0.001 0.0024 0.0022
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Leishmania major glucose transporter, lmgt1 0.001 0.0024 0.0264
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0134 0.1751
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Trypanosoma brucei cytochrome P450, putative 0.0013 0.0045 0.0565
Echinococcus granulosus intermediate filament protein 0.0027 0.0147 0.0145
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Schistosoma mansoni apoferritin-2 0.0008 0.0013 0.0013
Loa Loa (eye worm) sugar transporter 0.001 0.0024 0.0073
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0393 0.4716
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Leishmania major hypothetical protein, conserved 0.0008 0.001 0.0096
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0008 0.001 0.0105
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Loa Loa (eye worm) hypothetical protein 0.0047 0.029 0.0965
Onchocerca volvulus 0.001 0.0024 0.0064
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0008 0.001 0.0039
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0695 0.1649
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0116 0.0789 0.0789
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0008 0.001 0.0027
Entamoeba histolytica hypothetical protein, conserved 0.0008 0.001 0.0019
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.001 0.0024 0.0108
Trypanosoma brucei glucose transporter, putative 0.001 0.0024 0.029
Schistosoma mansoni glucose transport protein 0.001 0.0024 0.0024
Brugia malayi oxidoreductase 0.0008 0.001 0.0027
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0008 0.001 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Onchocerca volvulus 0.0008 0.001 0.0023
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0121 0.0587
Echinococcus granulosus cpg binding protein 0.0031 0.0178 0.0176
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0121 0.0587
Leishmania major 3-keto-dihydrosphingosine reductase 0.0008 0.001 0.0096
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0116 0.0789 0.3876
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0337 0.0335
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0147 0.0485
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0022 0.0022
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.029 0.029
Mycobacterium tuberculosis Possible oxidoreductase 0.0008 0.001 0.0039
Loa Loa (eye worm) dehydrogenase 0.0008 0.001 0.0027
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.029 0.0965
Loa Loa (eye worm) dehydrogenase 0.0008 0.001 0.0027
Schistosoma mansoni ferritin 0.0008 0.0013 0.0013
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0038 0.0477
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0047 0.0045
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0134 0.1595
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.001 0.0096
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0008 0.001 0.0105
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.029 0.0288
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0035 0.0112
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0393 0.0391
Trypanosoma brucei glucose transporter, putative 0.001 0.0024 0.029
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0008 0.001 0.0008
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.001 0.0019
Trypanosoma cruzi hexose transporter, putative 0.001 0.0024 0.029
Onchocerca volvulus 0.0008 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0026 0.0143 0.0474
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Trypanosoma cruzi hexose transporter, putative 0.001 0.0024 0.029
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0549 0.1833
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0171 0.0401
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0096
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0008 0.001 0.0027
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0008 0.0013 0.0057
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0421 0.2988 1
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0019 0.0056
Brugia malayi Sugar transporter family protein 0.001 0.0024 0.0073
Echinococcus multilocularis lamin dm0 0.0027 0.0147 0.0145
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0166 0.055
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Schistosoma mansoni retinal dehydrogenase 0.0008 0.001 0.001
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.001 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0059 0.0689
Leishmania major short chain dehydrogenase/reductase, putative 0.0008 0.001 0.0096
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0008 0.001 0.0105
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Trypanosoma cruzi short chain dehydrogenase, putative 0.0008 0.001 0.0105
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0008 0.001 0.0105
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Toxoplasma gondii sugar transporter ST3 0.001 0.0024 0.0264
Mycobacterium ulcerans bacterioferritin BfrA 0.0008 0.0013 0.0057
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0171 0.0402
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0008 0.001 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0002 0.000000000063838
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0103 0.0695 0.2322
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0121 0.0283
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0057 0.0185
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.001 0.0105
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Brugia malayi Cytochrome P450 family protein 0.0013 0.0045 0.0143
Schistosoma mansoni short chain dehydrogenase 0.0008 0.001 0.001
Onchocerca volvulus 0.0027 0.0147 0.0426
Trypanosoma cruzi sugar transporter, putative 0.001 0.0024 0.029
Schistosoma mansoni hypothetical protein 0.0336 0.237 0.237
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.001 0.0039
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0171 0.8287
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0757 0.3721
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0204 0.2438
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.001 0.0039
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0047 0.0045
Brugia malayi POT family protein 0.0081 0.0538 0.1796
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Brugia malayi mbt repeat family protein 0.0047 0.029 0.0965
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.001 0.0008
Mycobacterium ulcerans dehydrogenase 0.0008 0.001 0.0039
Echinococcus multilocularis solute carrier family 22 0.001 0.0024 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0002 0.000000000063838
Echinococcus multilocularis musashi 0.0027 0.0147 0.0145
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0757 0.1796
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0757 0.253
Echinococcus granulosus ferritin 0.0008 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0008 0.001 0.0039
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0008 0.001 0.0105
Giardia lamblia Reductase, putative 0.0008 0.001 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0393 0.0393
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Schistosoma mansoni ferritin light chain 0.0008 0.0013 0.0013
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.001 0.0008
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0757 0.253
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0171 0.0402
Treponema pallidum bacterioferrin (TpF1) 0.0008 0.0013 0.0027
Leishmania major oxidoreductase-like protein 0.0008 0.001 0.0096
Trypanosoma brucei glucose transporter, putative 0.001 0.0024 0.029
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0008 0.001 0.001
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.029 0.0846
Echinococcus granulosus carbonyl reductase 1 0.0008 0.001 0.0008
Echinococcus granulosus hypothetical protein 0.0008 0.001 0.0008
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0008 0.001 0.0105
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0134 0.3246
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0485
Brugia malayi 6-phosphofructokinase 0.0112 0.0757 0.253
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0024 0.0022
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0008 0.001 0.0105
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0008 0.001 0.0019
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.001 0.0008
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0008 0.001 0.0105
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0171 0.0402
Loa Loa (eye worm) hypothetical protein 0.001 0.0024 0.0073
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.001 0.0019
Plasmodium vivax hexose transporter 0.001 0.0024 0.0365
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.001 0.0039
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0111 0.0261
Mycobacterium tuberculosis Possible oxidoreductase 0.0008 0.001 0.0039
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0103 0.0695 0.8365
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.001 0.0039
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0591 0.4209 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Echinococcus granulosus carbonyl reductase 1 0.0008 0.001 0.0008
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Plasmodium falciparum hexose transporter 0.001 0.0024 0.0719
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0591 0.4209 1
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0757 0.1796
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0027
Echinococcus multilocularis oxidoreductase 0.0008 0.001 0.0008
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0008 0.001 0.0039
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.001 0.0027
Mycobacterium ulcerans carveol-like dehydrogenase 0.0008 0.001 0.0039
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0204 0.2676
Trichomonas vaginalis sugar transport protein, putative 0.001 0.0024 0.0052
Schistosoma mansoni DNA helicase recq1 0.0009 0.0019 0.0019
Brugia malayi hypothetical protein 0.001 0.0024 0.0073
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0055
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0008 0.001 0.0039
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0019 0.0056
Entamoeba histolytica hypothetical protein 0.0008 0.001 0.0019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0134 0.0443
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0549 0.0547
Brugia malayi major facilitator superfamily protein 0.001 0.0024 0.0073
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.001 0.0039
Echinococcus granulosus mitogen activated protein kinase 3 0.0103 0.0695 0.0694
Toxoplasma gondii transporter, major facilitator family protein 0.001 0.0024 0.0264
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.001 0.0105
Toxoplasma gondii oxidoreductase, putative 0.0008 0.001 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0024 0.0052
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0121 0.5729
Onchocerca volvulus 0.0008 0.001 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0002 0.000000000063838
Mycobacterium ulcerans dehydrogenase/reductase 0.0008 0.001 0.0039
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.001 0.0039
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.001 0.0039
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0008 0.001 0.0039
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0549 0.0549
Trypanosoma brucei glucose transporter 1E 0.001 0.0024 0.029
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0757 0.3721
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0831 0.4083
Echinococcus granulosus Solute carrier family 22 5 0.103 0.7369 0.7369
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0134 0.1751
Loa Loa (eye worm) oxidoreductase 0.0008 0.001 0.0027
Onchocerca volvulus 0.001 0.0024 0.0064
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.001 0.0096
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0024 0.0022
Echinococcus granulosus bloom syndrome protein 0.0022 0.0111 0.011
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0757 0.1796
Trichomonas vaginalis sugar transporter, putative 0.001 0.0024 0.0052
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0831 1
Onchocerca volvulus 0.001 0.0024 0.0064

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 8 nM Binding affinity at human adenosine A2A receptor ChEMBL. 18411049
Ki (binding) = 8 nM Binding affinity at human adenosine A2A receptor ChEMBL. 18411049
Ki (binding) = 534 nM Binding affinity at human adenosine A1 receptor ChEMBL. 18411049
Ki (binding) = 534 nM Binding affinity at human adenosine A1 receptor ChEMBL. 18411049

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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