Detailed information for compound 546475

Basic information

Technical information
  • TDR Targets ID: 546475
  • Name: (2S)-2-[[(2S,3S)-2-[[(2R)-2-benzyl-4-(hydroxy amino)-4-oxo-butanoyl]amino]-3-methyl-pentano yl]amino]-4-methyl-pentanoic acid
  • MW: 449.541 | Formula: C23H35N3O6
  • H donors: 5 H acceptors: 6 LogP: 2.61 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@@H]([C@@H](C(=O)N[C@H](C(=O)O)CC(C)C)NC(=O)[C@H](Cc1ccccc1)CC(=O)NO)C
  • InChi: 1S/C23H35N3O6/c1-5-15(4)20(22(29)24-18(23(30)31)11-14(2)3)25-21(28)17(13-19(27)26-32)12-16-9-7-6-8-10-16/h6-10,14-15,17-18,20,32H,5,11-13H2,1-4H3,(H,24,29)(H,25,28)(H,26,27)(H,30,31)/t15-,17+,18-,20-/m0/s1
  • InChiKey: MWZOULASPWUGJJ-NFBUACBFSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-[[(2S,3S)-2-[[(2R)-2-benzyl-4-(hydroxyamino)-1,4-dioxobutyl]amino]-3-methyl-1-oxopentyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[(2S,3S)-2-[[(2R)-4-(hydroxyamino)-4-oxo-2-(phenylmethyl)butanoyl]amino]-3-methyl-pentanoyl]amino]-4-methyl-pentanoic acid
  • (2S)-2-[[(2S,3S)-2-[[(2R)-2-benzyl-4-(hydroxyamino)-4-keto-butanoyl]amino]-3-methyl-pentanoyl]amino]-4-methyl-valeric acid
  • (2S)-2-[[(2S,3S)-2-[[(2R)-2-benzyl-4-(hydroxyamino)-4-oxobutanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
  • JMV 390-1
  • (2S)-2-[[(2S,3S)-2-[[(2R)-4-(hydroxyamino)-4-oxo-2-(phenylmethyl)butanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[(2S,3S)-2-[[(2R)-4-(hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]amino]-3-methyl-1-oxopentyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[(2S,3S)-2-[[(2R)-2-(benzyl)-4-(hydroxyamino)-4-keto-butanoyl]amino]-3-methyl-pentanoyl]amino]-4-methyl-valeric acid
  • 148473-36-3
  • L-Leucine, N-((2R)-4-(hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl)-L-isoleucyl-
  • Jmv-390-1
  • N-((2R)-4-(Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl)-L-isoleucyl-L-leucine
  • L-Leucine, N-(N-(4-(hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl)-L-isoleucyl)-, (R)-
  • N-[(2R)-2-BENZYL-4-(HYDROXYAMINO)-4-OXOBUTANOYL]-L-ISOLEUCYL-L-LEUCINE
  • N-(3-((Hydroxyamino)carbonyl)-2-benzyl-1-oxoprolyl)-L-isoleucine-L-leucine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0016 0.0319
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0332 0.0515 0.2087
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.005
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0612 0.0996 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0052 0.0031 0.0038
Brugia malayi Thioredoxin reductase 0.0233 0.0343 0.0435
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0086 0.009 0.0894
Brugia malayi Nuclear hormone receptor family member nhr-25 0.011 0.0131 0.0165
Loa Loa (eye worm) hypothetical protein 0.0044 0.0017 0.002
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0016 0.0197
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0015 0.0143
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Echinococcus granulosus RUN 0.0062 0.0049 0.0062
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0205 0.0296 0.0296
Brugia malayi hypothetical protein 0.0058 0.0042 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-14 0.011 0.0131 0.0165
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0397 0.0625 0.0794
Loa Loa (eye worm) hhat protein 0.0397 0.0625 0.0793
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0009 0.0009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.011 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0058 0.0042 0.0052
Toxoplasma gondii LsmAD domain-containing protein 0.0127 0.0161 0.1572
Brugia malayi nuclear hormone receptor family member nhr-6 0.0052 0.0031 0.0038
Brugia malayi steroid hormone receptor 0.011 0.0131 0.0165
Schistosoma mansoni ap endonuclease 0.0042 0.0014 0.0017
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0041 0.0013 0.0034
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0044 0.0017 0.005
Trypanosoma cruzi GUP1, putative 0.0397 0.0625 0.6275
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0397 0.0625 0.0794
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0707 0.116 0.1472
Leishmania major hypothetical protein, conserved 0.0044 0.0017 0.0154
Plasmodium falciparum phosphodiesterase gamma, putative 0.0044 0.0017 0.005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0081 0.0803
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0014 0.0051
Schistosoma mansoni aldehyde dehydrogenase 0.0034 0.0001 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0011 0.0041
Onchocerca volvulus 0.011 0.0131 0.0528
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0007 0.0008
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0034 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.011 0.0131 0.0165
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0397 0.0625 0.0625
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0397 0.0625 0.0793
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0089 0.0095 0.012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0081 0.0803
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0015 0.014
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0084 0.0106
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0017 0.0158
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Echinococcus granulosus cytochrome P450 2K1 0.0041 0.0013 0.0017
Toxoplasma gondii ABC1 family protein 0.0328 0.0508 0.4975
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0044 0.0017 0.0021
Schistosoma mansoni importin beta-1 0.0058 0.0042 0.0053
Loa Loa (eye worm) hypothetical protein 0.0328 0.0508 0.0643
Onchocerca volvulus 0.0195 0.0278 0.1126
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0625 0.1019 0.2863
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0014 0.0016
Brugia malayi hypothetical protein 0.0127 0.0161 0.0203
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0017 0.0158
Mycobacterium ulcerans beta-lactamase 0.0328 0.0508 0.4975
Trypanosoma brucei cytochrome P450, putative 0.006 0.0046 0.045
Loa Loa (eye worm) hypothetical protein 0.0093 0.0103 0.0129
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.011 0.0131 0.0131
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0052 0.0031 0.004
Loa Loa (eye worm) hypothetical protein 0.0062 0.0049 0.0061
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0034 0.0001 0.0001
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0041 0.0013 0.0121
Leishmania major glycerol uptake protein, putative 0.0397 0.0625 0.6131
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0041 0.0013 0.0034
Plasmodium vivax multidomain scavenger receptor, putative 0.0062 0.0049 0.0574
Giardia lamblia DINP protein human, muc B family 0.0039 0.0009 0.0163
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0081 0.0803
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0156 0.0211 0.0854
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0023 0.0088
Loa Loa (eye worm) hypothetical protein 0.0039 0.0009 0.001
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0044 0.0017 0.0064
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0009 0.0031
Brugia malayi beta-lactamase 0.0328 0.0508 0.0643
Brugia malayi Doublecortin family protein 0.0062 0.0049 0.0061
Onchocerca volvulus 0.0397 0.0625 0.2537
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0044 0.0017 0.002
Echinococcus multilocularis ornithine aminotransferase 0.0089 0.0095 0.0095
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0089 0.0095 0.0918
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0015 0.0143
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0044 0.0017 0.0158
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0044 0.0017 0.0021
Echinococcus multilocularis musashi 0.0052 0.0032 0.0032
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0034 0.0001 0.0001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0007 0.0078
Loa Loa (eye worm) RNA binding protein 0.0065 0.0054 0.0067
Plasmodium vivax SET domain protein, putative 0.0188 0.0265 0.4111
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0707 0.116 0.1473
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0007 0.0007
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0619 0.1008 0.1279
Echinococcus multilocularis thioredoxin glutathione reductase 0.0233 0.0343 0.0343
Loa Loa (eye worm) glutaminase 2 0.0269 0.0406 0.0514
Onchocerca volvulus 0.02 0.0287 0.1164
Loa Loa (eye worm) hypothetical protein 0.0058 0.0042 0.0052
Loa Loa (eye worm) hypothetical protein 0.0397 0.0625 0.0793
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0159 0.0216 0.2113
Echinococcus granulosus Polycystic kidney disease protein 0.0062 0.0049 0.0062
Loa Loa (eye worm) MBOAT family protein 0.4601 0.7875 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0041 0.0013 0.0118
Mycobacterium ulcerans lipase LipD 0.0328 0.0508 0.4975
Schistosoma mansoni DNA polymerase eta 0.0039 0.0009 0.0011
Leishmania major glycerol uptake protein, putative 0.0397 0.0625 0.6131
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0015 0.0143
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0044 0.0017 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-19 0.011 0.0131 0.0165
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0007 0.0059
Trichomonas vaginalis porcupine, putative 0.0397 0.0625 0.2537
Plasmodium falciparum phosphodiesterase delta, putative 0.0044 0.0017 0.005
Toxoplasma gondii thioredoxin reductase 0.0233 0.0343 0.3362
Echinococcus multilocularis zinc finger protein 0.4205 0.7191 0.7191
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0159 0.0216 0.2162
Schistosoma mansoni zinc finger protein 0.0035 0.0001 0.0002
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0081 0.0081 0.0101
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0041 0.0013 0.0118
Schistosoma mansoni inositol monophosphatase 0.0036 0.0004 0.0005
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0009 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-41 0.011 0.0131 0.0165
Loa Loa (eye worm) hypothetical protein 0.0243 0.0361 0.0457
Mycobacterium tuberculosis Probable dehydrogenase 0.0531 0.0858 0.241
Trypanosoma cruzi glycerol uptake protein, putative 0.0397 0.0625 0.6275
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0081 0.0081 0.11
Loa Loa (eye worm) follicle stimulating hormone receptor 0.2563 0.436 0.5536
Plasmodium vivax glutathione reductase, putative 0.0233 0.0343 0.5391
Loa Loa (eye worm) histone methyltransferase 0.0062 0.0048 0.006
Echinococcus granulosus mitogen activated protein kinase 0.0159 0.0216 0.0275
Mycobacterium tuberculosis Probable reductase 0.0531 0.0858 0.241
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0151 0.0202 0.0566
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0159 0.0216 0.2162
Schistosoma mansoni lamin 0.0052 0.0032 0.0041
Echinococcus granulosus histone lysine methyltransferase setb 0.0205 0.0296 0.0376
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.011 0.0131 0.0167
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0009 0.001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0328 0.0508 0.0645
Plasmodium falciparum ataxin-2 like protein, putative 0.0127 0.0161 0.241
Onchocerca volvulus 0.0328 0.0508 0.2059
Brugia malayi MBOAT family protein 0.0397 0.0625 0.0793
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Brugia malayi nuclear hormone receptor 0.011 0.0131 0.0165
Loa Loa (eye worm) hypothetical protein 0.0397 0.0625 0.0793
Loa Loa (eye worm) hypothetical protein 0.0956 0.1591 0.2019
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0031 0.004
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0015 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0041 0.0013 0.0034
Onchocerca volvulus 0.0188 0.0265 0.1073
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0089 0.0095 0.0918
Entamoeba histolytica hypothetical protein 0.0047 0.0023 0.0284
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0014 0.0268
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0017 0.0158
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0054 0.0069
Schistosoma mansoni hypothetical protein 0.171 0.2891 0.3671
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Loa Loa (eye worm) inositol-1 0.0036 0.0004 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.011 0.0131 0.0167
Trypanosoma cruzi GUP1, putative 0.0397 0.0625 0.6275
Loa Loa (eye worm) hypothetical protein 0.004 0.0011 0.0013
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0046 0.0057
Loa Loa (eye worm) hypothetical protein 0.0328 0.0508 0.0643
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0062 0.0048 0.0061
Loa Loa (eye worm) glutathione reductase 0.0233 0.0343 0.0435
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0397 0.0625 0.0794
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0081 0.0081 0.855
Onchocerca volvulus 0.0099 0.0112 0.0451
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0397 0.0625 0.0625
Trypanosoma brucei protein kinase, putative 0.0159 0.0216 0.2162
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.0236 0.0236
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0041 0.0013 0.0118
Schistosoma mansoni lipoxygenase 0.0243 0.0361 0.0458
Echinococcus granulosus dna polymerase eta 0.0039 0.0009 0.0011
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0041 0.0013 0.0034
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0041 0.0013 0.0118
Brugia malayi hypothetical protein 0.0062 0.0049 0.0061
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0612 0.0996 1
Echinococcus multilocularis tumor protein p63 0.137 0.2303 0.2303
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.005
Loa Loa (eye worm) hypothetical protein 0.0127 0.0161 0.0203
Loa Loa (eye worm) hypothetical protein 0.2438 0.4146 0.5264
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0397 0.0625 0.8182
Trypanosoma cruzi hypothetical protein, conserved 0.0328 0.0508 0.5092
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0397 0.0625 0.6131
Echinococcus granulosus neuropeptide receptor A26 0.1467 0.2471 0.3139
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0014 0.0124
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0081 0.0081 0.0103
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0007 0.0024
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0178 0.0248 0.0314
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0084 0.0084
Echinococcus multilocularis thyroid hormone receptor alpha 0.011 0.0131 0.0131
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0159 0.0216 0.2162
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0308 0.0472 0.0472
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0041 0.0013 0.0034
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0038 0.0008 0.0069
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0004 0.0005
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Schistosoma mansoni inositol monophosphatase 0.0036 0.0004 0.0005
Brugia malayi Glycosyl hydrolases family 31 protein 0.0171 0.0236 0.0298
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Plasmodium vivax hypothetical protein, conserved 0.0328 0.0508 0.8076
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0041 0.0013 0.0121
Trypanosoma brucei hypothetical protein, conserved 0.0328 0.0508 0.5092
Schistosoma mansoni retinoid-x-receptor (RXR) 0.011 0.0131 0.0167
Onchocerca volvulus Huntingtin homolog 0.038 0.0597 0.2424
Mycobacterium tuberculosis Probable esterase LipL 0.0328 0.0508 0.1425
Onchocerca volvulus 0.0062 0.0049 0.0194
Echinococcus multilocularis mitogen activated protein kinase 3 0.0159 0.0216 0.0216
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0623 0.1016 0.4126
Trichomonas vaginalis transmembrane protein nessy, putative 0.0397 0.0625 0.2537
Echinococcus multilocularis nuclear receptor nhr 48 0.0052 0.0031 0.0031
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0007 0.0024
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0038 0.0008 0.0069
Loa Loa (eye worm) intermediate filament protein 0.0052 0.0032 0.004
Plasmodium vivax hypothetical protein, conserved 0.0113 0.0136 0.2002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0308 0.0472 0.4627
Treponema pallidum NADH oxidase 0.0081 0.0081 0.128
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0044 0.0017 0.0021
Schistosoma mansoni cpg binding protein 0.019 0.0269 0.0342
Mycobacterium leprae Conserved hypothetical protein 0.0041 0.0013 0.0119
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0308 0.0472 0.0598
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.006 0.0046 0.0439
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0007 0.0008
Onchocerca volvulus 0.0052 0.0032 0.0127
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0084 0.0106
Schistosoma mansoni nuclear receptor 0.0052 0.0031 0.004
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0031 0.0122
Loa Loa (eye worm) acetyltransferase 0.0162 0.0222 0.028
Echinococcus granulosus mixed lineage leukemia protein mll 0.0051 0.003 0.0038
Brugia malayi hypothetical protein 0.0093 0.0103 0.0129
Echinococcus granulosus neuropeptide s receptor 0.1467 0.2471 0.3139
Trypanosoma brucei trypanothione reductase 0.0233 0.0343 0.3441
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0397 0.0625 0.0625
Mycobacterium tuberculosis Probable aminotransferase 0.0623 0.1016 0.2854
Entamoeba histolytica hypothetical protein, conserved 0.0397 0.0625 0.8182
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0397 0.0625 0.8182
Echinococcus multilocularis sterol O acyltransferase 1 0.0397 0.0625 0.0625
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0041 0.0013 0.0034
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0041 0.0013 0.0118
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Brugia malayi Intermediate filament tail domain containing protein 0.0052 0.0032 0.004
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.037 0.058 0.0735
Schistosoma mansoni hypothetical protein 0.0081 0.0082 0.0104
Echinococcus granulosus geminin 0.0331 0.0512 0.0651
Giardia lamblia NADH oxidase lateral transfer candidate 0.0081 0.0081 0.1696
Echinococcus granulosus Aminotransferase class III 0.0089 0.0095 0.012
Brugia malayi hypothetical protein 0.0062 0.0049 0.0061
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.003 0.0038
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0009 0.001
Schistosoma mansoni cytochrome P450 0.0041 0.0013 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.011 0.0131 0.0165
Brugia malayi intermediate filament protein 0.0052 0.0032 0.004
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0015 0.0018
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0007 0.0009
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.0158
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0041 0.0013 0.0118
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0707 0.116 0.1472
Loa Loa (eye worm) hypothetical protein 0.0093 0.0103 0.0129
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0044 0.0017 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0188 0.0265 0.0337
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0089 0.0095 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0131 0.0165
Echinococcus granulosus ecdysone induced protein 78C 0.011 0.0131 0.0167
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0015 0.0019
Echinococcus multilocularis zinc finger protein 0.0035 0.0001 0.0001
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0027 0.0106
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0058 0.0042 0.0042
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0044 0.0017 0.0064
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0289 0.0441 0.4419
Leishmania major cytochrome p450-like protein 0.0041 0.0013 0.0118
Schistosoma mansoni thyroid hormone receptor 0.011 0.0131 0.0167
Schistosoma mansoni aldehyde dehydrogenase 0.0034 0.0001 0.0001
Plasmodium falciparum glutathione reductase 0.0233 0.0343 0.5391
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0328 0.0508 0.0645
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0188 0.0265 0.0337
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0308 0.0472 0.1915
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0041 0.0013 0.0118
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0081 0.0082 0.0104
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0041 0.0013 0.0034
Schistosoma mansoni transcription factor LCR-F1 0.0477 0.0764 0.097
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0044 0.0017 0.0064
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0044 0.0017 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0011 0.0041
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0009 0.0011
Plasmodium vivax importin-beta 2, putative 0.0058 0.0042 0.0457
Trypanosoma cruzi trypanothione reductase, putative 0.0233 0.0343 0.3441
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Brugia malayi hypothetical protein 0.0956 0.1591 0.2019
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0081 0.0081 0.0785
Loa Loa (eye worm) MBOAT family protein 0.0397 0.0625 0.0793
Trichomonas vaginalis conserved hypothetical protein 0.0332 0.0515 0.2087
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0007 0.0009
Trypanosoma brucei PAB1-binding protein , putative 0.0127 0.0161 0.1608
Echinococcus multilocularis mitogen activated protein kinase 0.0159 0.0216 0.0216
Brugia malayi conserved hypotetical protein 0.0052 0.0031 0.0038
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0017 0.0021
Schistosoma mansoni aldehyde dehydrogenase 0.0034 0.0001 0.0001
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0612 0.0996 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.0064
Loa Loa (eye worm) hypothetical protein 0.0328 0.0508 0.0643
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0294 0.0448 0.4496
Toxoplasma gondii NADPH-glutathione reductase 0.0081 0.0081 0.0785
Loa Loa (eye worm) hypothetical protein 0.02 0.0287 0.0364
Schistosoma mansoni hypothetical protein 0.0477 0.0764 0.097
Loa Loa (eye worm) DR-78 0.0052 0.0031 0.0038
Brugia malayi ecdysteroid receptor 0.011 0.0131 0.0165
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0159 0.0216 0.2113
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0041 0.0013 0.0034
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0041 0.0013 0.0118
Echinococcus granulosus nuclear receptor 2DBD gamma 0.011 0.0131 0.0167
Schistosoma mansoni cpg binding protein 0.019 0.0269 0.0342
Brugia malayi nuclear receptor NHR-88 0.011 0.0131 0.0165
Schistosoma mansoni microtubule-associated protein tau 0.2132 0.3617 0.4594
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0397 0.0625 0.8182
Trichomonas vaginalis penicillin-binding protein, putative 0.0328 0.0508 0.2059
Mycobacterium ulcerans hypothetical protein 0.0328 0.0508 0.4975
Loa Loa (eye worm) hypothetical protein 0.011 0.0131 0.0165
Mycobacterium tuberculosis Conserved hypothetical protein 0.0322 0.0497 0.1395
Brugia malayi RNA, U transporter 1 0.0165 0.0226 0.0285
Schistosoma mansoni hypothetical protein 0.0057 0.004 0.0051
Loa Loa (eye worm) cytochrome P450 0.0041 0.0013 0.0015
Brugia malayi MBOAT family protein 0.4601 0.7875 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0082 0.0102
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0089 0.0095 0.0119
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Onchocerca volvulus 0.0328 0.0508 0.2059
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0049 0.0062
Loa Loa (eye worm) hypothetical protein 0.0328 0.0508 0.0643
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0081 0.0081 0.855
Schistosoma mansoni ran 0.0043 0.0015 0.0019
Mycobacterium leprae putative cytochrome p450 0.0041 0.0013 0.0119
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0156 0.0211 0.0854
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Brugia malayi Cytochrome P450 family protein 0.0041 0.0013 0.0015
Mycobacterium ulcerans hypothetical protein 0.0322 0.0497 0.4871
Plasmodium vivax thioredoxin reductase, putative 0.0233 0.0343 0.5391
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0034 0.0001 0.0001
Trypanosoma brucei glycerol uptake protein, putative 0.0397 0.0625 0.6275
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0023 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0011 0.0041
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0031 0.0031
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0308 0.0472 0.4736
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0031 0.0122
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0042 0.0052
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0397 0.0625 1
Echinococcus granulosus dna polymerase kappa 0.0039 0.0009 0.0011
Entamoeba histolytica hypothetical protein 0.0477 0.0764 1
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0044 0.0017 0.0021
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0009 0.0077
Echinococcus multilocularis beta LACTamase domain containing family member 0.0328 0.0508 0.0508
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0041 0.0013 0.0118
Schistosoma mansoni aldehyde dehydrogenase 0.0034 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0011 0.0041
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Brugia malayi Bromodomain containing protein 0.0044 0.0018 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0041 0.0013 0.0034
Echinococcus multilocularis dnaJ subfamily B 0.171 0.2891 0.2891
Plasmodium falciparum thioredoxin reductase 0.0233 0.0343 0.5391
Loa Loa (eye worm) hypothetical protein 0.0308 0.0472 0.0598
Schistosoma mansoni cellular tumor antigen P53 0.02 0.0287 0.0365
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.0362 0.0459
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0623 0.1016 0.9968
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0136 0.0549
Brugia malayi tailless protein 0.0052 0.0031 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0058 0.0042 0.0052
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0052 0.0031 0.0038
Schistosoma mansoni Tr4/Tr2 (homologue) 0.011 0.0131 0.0167
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0625 0.1019 1
Echinococcus multilocularis muscleblind protein 1 0.2438 0.4146 0.4146
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0328 0.0508 0.1425
Toxoplasma gondii hypothetical protein 0.025 0.0373 0.3657
Entamoeba histolytica hypothetical protein 0.0477 0.0764 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0059 0.0044 0.0055
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0397 0.0625 0.0625
Schistosoma mansoni cpg binding protein 0.0178 0.0248 0.0315
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0089 0.0095 0.0263
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0017 0.0021
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0308 0.0472 0.4736
Loa Loa (eye worm) cytochrome P450 family protein 0.0163 0.0222 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0011 0.0041
Echinococcus granulosus microtubule associated protein 2 0.2132 0.3617 0.4594
Toxoplasma gondii cytochrome p450 superfamily protein 0.0041 0.0013 0.0118
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0041 0.0013 0.0034
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0034 0.0001 0.0001
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0294 0.0448 0.0569
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0031 0.004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0707 0.116 0.1473
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.4601 0.7875 1
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0034 0.0001 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0027 0.0035
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0014 0.0127
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0294 0.0448 0.1818
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Leishmania major glycerol uptake protein, putative 0.0397 0.0625 0.6131
Entamoeba histolytica Ran family GTPase 0.0043 0.0015 0.0186
Echinococcus granulosus o acyltransferase membrane bound domain 0.0397 0.0625 0.0794
Plasmodium falciparum ornithine aminotransferase 0.0089 0.0095 0.1321
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0009 0.01
Echinococcus granulosus lamin 0.0052 0.0032 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0205 0.0296 0.0376
Schistosoma mansoni polycystin 1-related 0.0062 0.0049 0.0062
Leishmania major cytochrome p450-like protein 0.0041 0.0013 0.0118
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0062 0.0048 0.0048
Leishmania major hypothetical protein, conserved 0.0397 0.0625 0.6131
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0017 0.0158
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0041 0.0013 0.0118
Mycobacterium tuberculosis Conserved protein 0.0328 0.0508 0.1425
Mycobacterium ulcerans L-lysine aminotransferase 0.0089 0.0095 0.0918
Mycobacterium ulcerans putative regulatory protein 0.0113 0.0136 0.1326
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.011 0.0131 0.0167
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0027 0.0256
Toxoplasma gondii aldehyde dehydrogenase 0.0625 0.1019 1
Leishmania major cytochrome p450-like protein 0.006 0.0046 0.0439
Leishmania major hypothetical protein, conserved 0.0328 0.0508 0.4975
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Schistosoma mansoni hypothetical protein 0.0034 0.0001 0.0001
Leishmania major DNA polymerase eta, putative 0.0039 0.0009 0.0075
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0044 0.0017 0.002
Entamoeba histolytica vacuolar protein sorting 26 0.0397 0.0625 0.8182
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0041 0.0013 0.0118
Brugia malayi nuclear receptor RXR 0.0052 0.0031 0.0038
Echinococcus granulosus retinoic acid receptor rxr beta a 0.011 0.0131 0.0167
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0007 0.0024
Echinococcus granulosus thioredoxin glutathione reductase 0.0233 0.0343 0.0436
Trypanosoma cruzi PAB1-binding protein , putative 0.0127 0.0161 0.1608
Echinococcus multilocularis lamin 0.0052 0.0032 0.0032
Brugia malayi F/Y-rich N-terminus family protein 0.0063 0.0051 0.0063
Plasmodium vivax ornithine aminotransferase, putative 0.0089 0.0095 0.1321
Onchocerca volvulus 0.1461 0.2461 1
Echinococcus granulosus cpg binding protein 0.019 0.0269 0.0342
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0089 0.0095 0.0918
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0531 0.0858 0.241
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.0236 0.0236
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0041 0.0013 0.0034
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0181 0.0254 0.1028
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0081 0.0082 0.0102
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0004 0.0012
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0031 0.004
Echinococcus granulosus lysosomal alpha glucosidase 0.0171 0.0236 0.03
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0081 0.0081 0.0785
Schistosoma mansoni hypothetical protein 0.0081 0.0082 0.0104
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0044 0.0017 0.0021
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0054 0.0067
Brugia malayi hypothetical protein 0.0477 0.0764 0.0969
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0477 0.0764 0.0764
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0243 0.0361 0.0458
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0328 0.0508 0.1425
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0041 0.0013 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0216 0.0874
Echinococcus granulosus FTZ F1 alpha 0.011 0.0131 0.0167
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0044 0.0017 0.002
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0081 0.0081 0.0785
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.011 0.0131 0.0167
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0081 0.0081 0.0803
Brugia malayi cytochrome P450 0.0041 0.0013 0.0015
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0162 0.0222 0.0222
Giardia lamblia Hypothetical protein 0.0044 0.0017 0.0333
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.0064
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0041 0.0013 0.0118
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0052 0.0031 0.004
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0081 0.0081 0.0103
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0027 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0011 0.0041
Schistosoma mansoni hypothetical protein 0.0041 0.0013 0.0017
Trypanosoma cruzi trypanothione reductase, putative 0.0081 0.0081 0.0803
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.011 0.0131 0.0131
Echinococcus multilocularis lamin dm0 0.0052 0.0032 0.0032
Trichomonas vaginalis D-aminoacylase, putative 0.0328 0.0508 0.2059
Echinococcus multilocularis ecdysone induced protein 78C 0.011 0.0131 0.0131
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0289 0.0441 0.4419
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.011 0.0131 0.0131
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.0362 0.0459
Brugia malayi Nuclear hormone receptor family member nhr-25 0.011 0.0131 0.0165
Echinococcus multilocularis survival motor neuron protein 1 0.0956 0.1591 0.1591
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0081 0.0081 0.11
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0034 0.0001 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0105 0.0122 0.122
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0049 0.0062
Brugia malayi photoreceptor-specific nuclear receptor 0.011 0.0131 0.0165
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0397 0.0625 0.0794
Onchocerca volvulus 0.0052 0.0032 0.0127
Loa Loa (eye worm) hypothetical protein 0.0058 0.0042 0.0052
Echinococcus multilocularis FTZ F1 alpha 0.011 0.0131 0.0131
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0009 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Brugia malayi nuclear hormone receptor family member odr-7 0.0052 0.0031 0.0038
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0188 0.0265 0.0265
Echinococcus granulosus lamin dm0 0.0052 0.0032 0.0041
Loa Loa (eye worm) hypothetical protein 0.0062 0.0049 0.0061
Schistosoma mansoni zinc finger protein 0.0052 0.0031 0.004
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0014 0.0036
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.0064
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Mycobacterium tuberculosis Probable lipase LipD 0.0328 0.0508 0.1425
Toxoplasma gondii hypothetical protein 0.0113 0.0136 0.1326
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.011 0.0131 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0011 0.0041
Onchocerca volvulus Bile acid receptor homolog 0.011 0.0131 0.0528
Echinococcus granulosus sterol O acyltransferase 1 0.0397 0.0625 0.0794
Brugia malayi glutaminase DH11.1 0.0269 0.0406 0.0514
Schistosoma mansoni zinc finger protein 0.4601 0.7875 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0011 0.0041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0031 0.0031
Echinococcus granulosus muscleblind protein 0.2438 0.4146 0.5264
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0041 0.0013 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-49 0.011 0.0131 0.0165
Mycobacterium leprae conserved hypothetical protein 0.0113 0.0136 0.1331
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Schistosoma mansoni hypothetical protein 0.0331 0.0512 0.0651
Schistosoma mansoni hypothetical protein 0.0175 0.0244 0.0309
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0328 0.0508 0.0643
Loa Loa (eye worm) hypothetical protein 0.011 0.0131 0.0165
Mycobacterium leprae conserved hypothetical protein 0.0328 0.0508 0.4991
Echinococcus granulosus o acyltransferase membrane bound domain 0.0397 0.0625 0.0794
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0707 0.116 0.1473
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.011 0.0131 0.0165
Echinococcus multilocularis microtubule associated protein 2 0.2132 0.3617 0.3617
Brugia malayi follicle stimulating hormone receptor 0.2563 0.436 0.5536
Schistosoma mansoni alpha-glucosidase 0.0147 0.0195 0.0248
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0009 0.0022
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0294 0.0448 0.1818
Echinococcus multilocularis geminin 0.0331 0.0512 0.0512
Loa Loa (eye worm) hypothetical protein 0.2438 0.4146 0.5264
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0007 0.0024
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0188 0.0265 0.2594
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0243 0.0361 0.0458
Loa Loa (eye worm) beta-lactamase 0.0328 0.0508 0.0643
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0011 0.0041
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0004 0.0029
Treponema pallidum alginate O-acetylation protein (algI) 0.0397 0.0625 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0084 0.0105
Entamoeba histolytica hypothetical protein 0.0477 0.0764 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0015 0.0026
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0049 0.0049
Brugia malayi Latrophilin receptor protein 2 0.0081 0.0082 0.0102
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.011 0.0131 0.0165
Schistosoma mansoni alpha glucosidase 0.0038 0.0007 0.0009
Trichomonas vaginalis glutathione reductase, putative 0.0081 0.0081 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0011 0.0041
Loa Loa (eye worm) doublecortin family protein 0.0062 0.0049 0.0061
Trichomonas vaginalis ran, putative 0.0043 0.0015 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0017 0.0158
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0081 0.0081 0.11
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0294 0.0448 0.1818
Loa Loa (eye worm) hypothetical protein 0.0059 0.0043 0.0053
Brugia malayi Cytochrome P450 family protein 0.006 0.0046 0.0057
Schistosoma mansoni nuclear receptor nhr-48 0.0052 0.0031 0.004
Entamoeba histolytica hypothetical protein 0.0477 0.0764 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.011 0.0131 0.0167
Loa Loa (eye worm) hypothetical protein 0.038 0.0597 0.0757
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0294 0.0448 0.1818
Leishmania major hypothetical protein, conserved 0.0038 0.0008 0.0068
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0159 0.0216 0.2113
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0009 0.0075
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0051 0.003 0.003
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0031 0.004
Brugia malayi nuclear receptor RXR 0.0058 0.0042 0.0052
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0034 0.0001 0.0001
Leishmania major trypanothione reductase 0.0233 0.0343 0.3362
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0054 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.025 0.0373 0.1513
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0308 0.0472 0.4736
Schistosoma mansoni bromodomain containing protein 0.008 0.008 0.0102
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0042 0.0399
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0625 0.1019 0.1295
Schistosoma mansoni sterol O-acyltransferase 1 0.0397 0.0625 0.0794
Loa Loa (eye worm) glutaminase 0.0269 0.0406 0.0514
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.0214 0.031 0.0393
Trichomonas vaginalis penicillin-binding protein, putative 0.0328 0.0508 0.2059
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0009 0.0075
Toxoplasma gondii hypothetical protein 0.0099 0.0112 0.1088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.011 0.0131 0.0165
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0294 0.0448 0.1818
Brugia malayi MAP kinase sur-1 0.0159 0.0216 0.0273
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0308 0.0472 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0155 0.021 0.0266
Toxoplasma gondii GAF domain-containing protein 0.0113 0.0136 0.1326
Brugia malayi PHD-finger family protein 0.004 0.0011 0.0013
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0031 0.0038
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0041 0.0013 0.0034
Brugia malayi nuclear receptor NHR-88 0.0052 0.0031 0.0038
Echinococcus granulosus intermediate filament protein 0.0052 0.0032 0.0041
Mycobacterium tuberculosis Conserved protein 0.0328 0.0508 0.1425
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Brugia malayi latrophilin 2 splice variant baaae 0.0175 0.0244 0.0308
Trypanosoma cruzi glycerol uptake protein, putative 0.0397 0.0625 0.6275
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0707 0.116 0.116
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0014 0.0016
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0082 0.0083 0.0333
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0007 0.0024
Mycobacterium ulcerans putative regulatory protein 0.0113 0.0136 0.1326
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.037 0.058 0.058
Brugia malayi CXXC zinc finger family protein 0.0178 0.0248 0.0314
Echinococcus granulosus zinc finger protein 0.4205 0.7191 0.9132
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Schistosoma mansoni coup transcription factor 0.011 0.0131 0.0167
Brugia malayi MBOAT family protein 0.0397 0.0625 0.0793
Trichomonas vaginalis esterase, putative 0.0328 0.0508 0.2059
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0052 0.0032 0.004
Plasmodium vivax phosphodiesterase gamma, putative 0.0044 0.0017 0.005
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0081 0.0081 0.0785
Schistosoma mansoni hypothetical protein 0.0081 0.0082 0.0104
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Brugia malayi hypothetical protein 0.038 0.0597 0.0757
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0007 0.0024
Echinococcus granulosus dnaJ subfamily B 0.171 0.2891 0.3671
Brugia malayi beta-lactamase family protein 0.0328 0.0508 0.0643
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0308 0.0472 0.0472
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0058 0.0042 0.0053
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0015 0.0302
Toxoplasma gondii histone lysine methyltransferase SET1 0.035 0.0545 0.5343
Loa Loa (eye worm) hypothetical protein 0.0082 0.0084 0.0105
Brugia malayi MH2 domain containing protein 0.0244 0.0362 0.0459
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0004 0.0012
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0023 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0007 0.006
Schistosoma mansoni lamin 0.0052 0.0032 0.0041
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0328 0.0508 0.4975
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0082 0.0083 0.0333
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0397 0.0625 0.0794
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0089 0.0095 0.0918
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0044 0.0017 0.005
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0308 0.0472 0.06
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0051 0.003 0.0038
Schistosoma mansoni hypothetical protein 0.0397 0.0625 0.0794
Plasmodium falciparum ataxin-2 like protein, putative 0.0127 0.0161 0.241
Loa Loa (eye worm) latrophilin receptor protein 2 0.0081 0.0082 0.0102
Schistosoma mansoni ap endonuclease 0.0042 0.0014 0.0017
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0289 0.0441 0.4318
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0041 0.0013 0.0034
Toxoplasma gondii hypothetical protein 0.0397 0.0625 0.6131
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0009 0.0011
Brugia malayi diacylglycerol acyltransferase 0.0397 0.0625 0.0793
Trichomonas vaginalis mercuric reductase, putative 0.0081 0.0081 0.0325
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0294 0.0448 0.4496
Loa Loa (eye worm) hypothetical protein 0.011 0.0131 0.0165
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0034 0.0001 0.0001
Echinococcus multilocularis snurportin 1 0.0619 0.1008 0.1008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0011 0.0041
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0171 0.0236 0.0298
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0041 0.0013 0.0121
Loa Loa (eye worm) hypothetical protein 0.0205 0.0296 0.0375
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0156 0.0211 0.0854
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0004 0.0028
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0308 0.0472 0.06
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0308 0.0472 0.1915
Brugia malayi hypothetical protein 0.0052 0.0031 0.0038
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0591 0.096 0.945
Leishmania major mitochondrial DNA polymerase beta 0.0612 0.0996 0.9771
Loa Loa (eye worm) thioredoxin reductase 0.0233 0.0343 0.0435
Brugia malayi acetyltransferase, GNAT family protein 0.0162 0.0222 0.028
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0044 0.0017 0.0158
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0044 0.0017 0.0158
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0531 0.0858 0.8442
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0294 0.0448 0.4496
Schistosoma mansoni aldehyde dehydrogenase 0.0625 0.1019 0.1295
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0008 0.0019
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.009 0.0894
Brugia malayi hypothetical protein 0.0082 0.0083 0.0105
Brugia malayi MBOAT family protein 0.0397 0.0625 0.0793
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0477 0.0764 0.097
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.005
Schistosoma mansoni hypothetical protein 0.0619 0.1008 0.128
Onchocerca volvulus 0.0082 0.0084 0.0335
Schistosoma mansoni survival motor neuron protein 0.0195 0.0278 0.0353
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0089 0.0095 0.0263
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.011 0.0131 0.0165
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0044 0.0017 0.0017
Brugia malayi MBOAT family protein 0.0397 0.0625 0.0793
Loa Loa (eye worm) hypothetical protein 0.0058 0.0042 0.0052
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0015 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0397 0.0625 0.2537
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0054 0.0067
Trypanosoma cruzi cytochrome P450, putative 0.006 0.0046 0.045
Loa Loa (eye worm) hypothetical protein 0.0074 0.007 0.0087
Brugia malayi ecdysone receptor 0.0052 0.0031 0.0038
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0052 0.0031 0.004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0007 0.0078
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0397 0.0625 0.0793
Schistosoma mansoni loxhd1 0.0062 0.0049 0.0062
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0243 0.0361 0.0361
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0014 0.1353
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0195 0.0278 0.0352
Loa Loa (eye worm) hypothetical protein 0.0328 0.0508 0.0643
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0057 0.004 0.0051
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0113 0.0136 0.038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0707 0.116 0.116
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0397 0.0625 0.0794
Trypanosoma cruzi cytochrome P450, putative 0.006 0.0046 0.045
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0397 0.0625 0.0794
Onchocerca volvulus 0.0178 0.0248 0.1005
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0044 0.0017 0.0158
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0294 0.0448 0.4496
Trypanosoma cruzi glycerol uptake protein, putative 0.0397 0.0625 0.6275
Schistosoma mansoni glutaminase 0.0269 0.0406 0.0515
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0531 0.0858 0.241
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0328 0.0508 0.0643
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0089 0.0095 1
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0623 0.1016 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0004 0.0028
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0051 0.003 0.003
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0027 0.0219
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0009 0.001
Echinococcus granulosus GPCR family 2 0.0081 0.0082 0.0104
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Schistosoma mansoni rab6-interacting 0.0062 0.0049 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.011 0.0131 0.0165
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.011 0.0131 0.0131
Echinococcus granulosus beta LACTamase domain containing family member 0.0328 0.0508 0.0645
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0007 0.0059
Brugia malayi Inositol-1 0.0036 0.0004 0.0004
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0044 0.0017 0.0021
Toxoplasma gondii exonuclease III APE 0.0042 0.0014 0.0124
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.011 0.0131 0.0131
Mycobacterium leprae Probable lipase LipE 0.0328 0.0508 0.4991
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0027 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0397 0.0625 0.2537
Mycobacterium ulcerans hypothetical protein 0.0623 0.1016 0.9968
Echinococcus multilocularis cpg binding protein 0.019 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0044 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0058 0.0042 0.0052
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0004 0.0029
Echinococcus granulosus o acyltransferase membrane bound domain 0.0397 0.0625 0.0794
Brugia malayi Steroid receptor seven-up type 2 0.011 0.0131 0.0165
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0256 0.0383 0.0486
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0034 0.0001 0.0001
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0332 0.0515 0.2087
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0256 0.0383 0.0486
Loa Loa (eye worm) hypothetical protein 0.011 0.0131 0.0165
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0049 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0017 0.0158
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0089 0.0095 0.0263
Plasmodium falciparum LCCL domain-containing protein 0.0062 0.0049 0.0574
Brugia malayi Calcitonin receptor-like protein seb-1 0.0256 0.0383 0.0486
Echinococcus multilocularis ornithine aminotransferase 0.0089 0.0095 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.011 0.0131 0.0165
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0081 0.0803
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0294 0.0448 0.1818
Echinococcus granulosus tumor protein p63 0.137 0.2303 0.2925
Echinococcus granulosus zinc finger protein 0.0035 0.0001 0.0002
Brugia malayi Muscleblind-like protein 0.2438 0.4146 0.5264
Loa Loa (eye worm) hypothetical protein 0.0058 0.0042 0.0052
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0009 0.0077
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0044 0.0017 0.0017
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0007 0.0024
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0042 0.0408
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0057 0.004 0.004
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0004 0.0037
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0054 0.0067
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0044 0.0017 0.002
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0081 0.0081 0.0081
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0081 0.0081 0.0225
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0004 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0625 0.1019 1
Trichomonas vaginalis conserved hypothetical protein 0.0397 0.0625 0.2537
Brugia malayi Nuclear hormone receptor family member nhr-1 0.011 0.0131 0.0165
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0041 0.0013 0.0034
Giardia lamblia Kinase, CMGC MAPK 0.0159 0.0216 0.4566
Schistosoma mansoni thyroid hormone receptor 0.011 0.0131 0.0167
Loa Loa (eye worm) MBOAT family protein 0.0397 0.0625 0.0793
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0014 0.0124
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0397 0.0625 0.0794
Loa Loa (eye worm) hypothetical protein 0.0044 0.0017 0.002
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.0158
Onchocerca volvulus 0.0052 0.0031 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.025 0.0373 0.1513
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0014 0.0014
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0017 0.0064
Giardia lamblia hypothetical protein 0.0044 0.0017 0.0333
Mycobacterium ulcerans glutaminase 0.0269 0.0406 0.3972
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0081 0.0082 0.0082
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0216 0.0874
Brugia malayi beta-lactamase family protein 0.0328 0.0508 0.0643
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0058 0.0042 0.0053
Loa Loa (eye worm) nuclear hormone receptor 0.0052 0.0031 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0216 0.0275
Entamoeba histolytica hypothetical protein 0.0397 0.0625 0.8182
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0011 0.0041
Brugia malayi Pre-SET motif family protein 0.1285 0.2156 0.2737
Echinococcus granulosus survival motor neuron protein 1 0.0956 0.1591 0.202
Plasmodium falciparum thioredoxin reductase 0.0081 0.0081 0.11
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0011 0.0041
Schistosoma mansoni nuclear hormone receptor 0.011 0.0131 0.0167
Mycobacterium tuberculosis Conserved protein 0.0328 0.0508 0.1425
Schistosoma mansoni steroid hormone receptor ad4bp 0.011 0.0131 0.0167
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0041 0.0013 0.0034
Mycobacterium tuberculosis Probable hydrolase 0.0328 0.0508 0.1425
Brugia malayi Importin beta-1 subunit 0.0058 0.0042 0.0052
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0081 0.0081 0.0785
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0308 0.0472 0.06
Loa Loa (eye worm) hypothetical protein 0.0175 0.0244 0.0308
Mycobacterium ulcerans acetylornithine aminotransferase 0.0089 0.0095 0.0918
Trypanosoma brucei glycerol uptake protein, putative 0.0397 0.0625 0.6275
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0081 0.0081 0.0785
Echinococcus granulosus snurportin 1 0.0619 0.1008 0.128
Loa Loa (eye worm) hypothetical protein 0.0047 0.0022 0.0027
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0016 0.0039
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.011 0.0131 0.0167
Echinococcus granulosus thyroid hormone receptor alpha 0.0052 0.0031 0.004
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0044 0.0017 0.0021
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0397 0.0625 0.0625
Brugia malayi nuclear hormone receptor 0.0052 0.0031 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0328 0.0508 0.2059
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0081 0.0081 0.0803
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Echinococcus multilocularis neuropeptide receptor A26 0.1467 0.2471 0.2471
Trypanosoma brucei unspecified product 0.0039 0.0009 0.0077
Loa Loa (eye worm) hypothetical protein 0.0256 0.0383 0.0486
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0294 0.0448 0.0569
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Mycobacterium ulcerans aldehyde dehydrogenase 0.0625 0.1019 1
Trichomonas vaginalis D-aminoacylase, putative 0.0328 0.0508 0.2059
Onchocerca volvulus Huntingtin homolog 0.038 0.0597 0.2424
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0089 0.0095 0.0918
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0004 0.0029
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0077 0.0074 0.0094
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0044 0.0017 0.0333
Toxoplasma gondii hypothetical protein 0.0113 0.0136 0.1326
Schistosoma mansoni retinoic acid receptor RXR 0.011 0.0131 0.0167
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0077 0.0074 0.0074
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0052 0.0031 0.0031
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0159 0.0216 0.0273
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0081 0.0081 0.0785
Echinococcus granulosus mitogen activated protein kinase 3 0.0159 0.0216 0.0275
Schistosoma mansoni aldehyde dehydrogenase 0.0625 0.1019 0.1295
Echinococcus granulosus importin subunit beta 1 0.0058 0.0042 0.0053
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0041 0.0013 0.0034
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0041 0.0013 0.0118
Echinococcus granulosus nuclear receptor 2DBD gamma 0.011 0.0131 0.0167
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0332 0.0515 0.2087
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0011 0.0041
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2097 0.3557 1
Echinococcus multilocularis dna polymerase eta 0.0039 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0062 0.0049 0.0062
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0081 0.0081 0.0785
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0041 0.0013 0.0118
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0011 0.0041
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.011 0.0131 0.0167
Mycobacterium tuberculosis Probable oxidoreductase 0.0591 0.096 0.2697
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0531 0.0858 0.241
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0397 0.0625 0.0794
Schistosoma mansoni rab6-interacting 0.0062 0.0049 0.0062
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0014 0.0202
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.0064
Schistosoma mansoni ran 0.0043 0.0015 0.0019
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1285 0.2156 0.2737
Echinococcus multilocularis Polycystic kidney disease protein 0.0062 0.0049 0.0049
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0294 0.0448 0.0448
Brugia malayi hypothetical protein 0.0052 0.0031 0.0038
Schistosoma mansoni alpha-glucosidase 0.0147 0.0195 0.0248
Trypanosoma cruzi PAB1-binding protein , putative 0.0127 0.0161 0.1608
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0015 0.0015
Echinococcus granulosus ornithine aminotransferase 0.0089 0.0095 0.012
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0041 0.0013 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-40 0.011 0.0131 0.0165
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0531 0.0858 0.241
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0181 0.0254 0.1028
Schistosoma mansoni nuclear receptor 0.0052 0.0031 0.004
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0041 0.0013 0.0034
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.011 0.0131 0.0165
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0081 0.0081 0.0803
Leishmania major hypothetical protein, conserved 0.0127 0.0161 0.1572
Trichomonas vaginalis set domain proteins, putative 0.1461 0.2461 1
Brugia malayi nuclear receptor NHR-67 0.0052 0.0031 0.0038
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0054 0.0069
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0294 0.0448 0.4496
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0294 0.0448 0.1818
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0017 0.0021
Brugia malayi Cytochrome P450 family protein 0.0163 0.0222 0.0281
Leishmania major DNA polymerase kappa, putative 0.0039 0.0009 0.0075
Schistosoma mansoni hypothetical protein 0.0331 0.0512 0.0651
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0591 0.096 0.2697
Schistosoma mansoni intermediate filament proteins 0.0052 0.0032 0.0041
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0041 0.0013 0.0118
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0009 0.0077
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0009 0.0077
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Trypanosoma cruzi hypothetical protein, conserved 0.0328 0.0508 0.5092
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0081 0.0081 0.11
Brugia malayi Pre-SET motif family protein 0.0188 0.0265 0.0335
Mycobacterium ulcerans aldehyde dehydrogenase 0.0625 0.1019 1
Leishmania major glycerol uptake protein, putative 0.0397 0.0625 0.6131
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0397 0.0625 0.0625
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0017 0.0021
Leishmania major glycerol uptake protein, putative 0.0397 0.0625 0.6131
Trichomonas vaginalis glutaminase, putative 0.0269 0.0406 0.1644
Loa Loa (eye worm) hypothetical protein 0.0328 0.0508 0.0643
Brugia malayi RNA binding protein 0.0065 0.0054 0.0067
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0308 0.0472 0.06
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.011 0.0131 0.0165
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0397 0.0625 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0233 0.0343 0.0963
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0623 0.1016 0.2854
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0041 0.0013 0.0034
Brugia malayi orphan nuclear receptor NR2E1 0.0052 0.0031 0.0038
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0591 0.096 0.2697
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0205 0.0296 0.0376
Onchocerca volvulus 0.0052 0.0031 0.0122
Onchocerca volvulus Protein ultraspiracle homolog 0.011 0.0131 0.0528
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0089 0.0095 0.0263
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0216 0.0874
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0042 0.0052
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0243 0.0361 0.0457
Schistosoma mansoni lipoxygenase 0.0131 0.0168 0.0214
Loa Loa (eye worm) steroid hormone receptor 0.011 0.0131 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0017 0.0064
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0081 0.0081 0.0803
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0397 0.0625 0.6131
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0042 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-3 0.011 0.0131 0.0165
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Trichomonas vaginalis helicase, putative 0.004 0.0011 0.0041
Brugia malayi Nuclear hormone receptor-like 1 0.011 0.0131 0.0165
Echinococcus multilocularis RUN 0.0062 0.0049 0.0049
Loa Loa (eye worm) CYP4Cod1 0.006 0.0046 0.0057
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0011 0.0041
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0397 0.0625 0.0794
Brugia malayi hypothetical protein 0.0058 0.0042 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0017 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-31 0.011 0.0131 0.0165
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0081 0.0082 0.0082
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Loa Loa (eye worm) PDE1B protein 0.0044 0.0017 0.002
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.4601 0.7875 0.7875
Leishmania major importin beta-1 subunit, putative 0.0047 0.0023 0.0213
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0041 0.0013 0.0034
Loa Loa (eye worm) nuclear receptor NHR-67 0.0052 0.0031 0.0038
Trypanosoma brucei glucosidase, putative 0.0038 0.0007 0.006
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0009 0.0011
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0294 0.0448 0.1818
Onchocerca volvulus 0.0328 0.0508 0.2059
Echinococcus multilocularis GPCR, family 2 0.0081 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0041 0.0013 0.0118
Brugia malayi Bromodomain containing protein 0.0093 0.0101 0.0127
Echinococcus granulosus tar DNA binding protein 0.0065 0.0054 0.0069
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0326 0.0505 0.0639
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Loa Loa (eye worm) hypothetical protein 0.0052 0.0032 0.004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0177 0.0247 0.0313
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Schistosoma mansoni hypothetical protein 0.0081 0.0082 0.0104
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0081 0.0082 0.0104
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0044 0.0017 0.0021
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0044 0.0017 0.0021
Echinococcus granulosus nuclear receptor nhr 48 0.0052 0.0031 0.004
Schistosoma mansoni eyes absent homolog 0.0093 0.0103 0.0131
Plasmodium falciparum importin beta, putative 0.0058 0.0042 0.0457
Echinococcus multilocularis ubiquitin specific protease 41 0.0308 0.0472 0.0472
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0014 0.0051
Brugia malayi glutathione reductase 0.0233 0.0343 0.0435
Loa Loa (eye worm) hypothetical protein 0.038 0.0597 0.0757
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0004 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0707 0.116 0.1473
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0009 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0007 0.006
Plasmodium falciparum GAF domain-related protein, putative 0.0113 0.0136 0.2002
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0007 0.0024
Echinococcus multilocularis muscleblind protein 0.2438 0.4146 0.4146
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0041 0.0013 0.0118
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0009 0.0022
Onchocerca volvulus 0.0062 0.0049 0.0194
Loa Loa (eye worm) hypothetical protein 0.0397 0.0625 0.0793
Schistosoma mansoni hypothetical protein 0.0195 0.0278 0.0353
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0044 0.0017 0.0021
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0042 0.0408
Loa Loa (eye worm) hypothetical protein 0.011 0.0131 0.0165
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0181 0.0254 0.2543
Loa Loa (eye worm) hypothetical protein 0.0397 0.0625 0.0793
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0017 0.0154
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0044 0.0017 0.0158
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0014 0.0127
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0046 0.0057
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0081 0.0081 0.0803
Echinococcus multilocularis neuropeptide s receptor 0.1467 0.2471 0.2471
Brugia malayi Cytochrome P450 family protein 0.006 0.0046 0.0057
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0023 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0054 0.0069
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0308 0.0472 0.1915
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0044 0.0017 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.011 0.0131 0.0167
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0058 0.0042 0.0053
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0017 0.005
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0159 0.0216 0.2162
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Leishmania major GTP-binding protein, putative 0.0043 0.0015 0.014
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0044 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.011 0.0131 0.0165
Mycobacterium tuberculosis Probable lipase LipE 0.0328 0.0508 0.1425
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0086 0.009 0.0894
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0162 0.0222 0.0282
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0151 0.0202 0.1977
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0041 0.0013 0.0118
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0081 0.0081 0.0803
Leishmania major hypothetical protein, conserved 0.0044 0.0017 0.0154
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0038 0.0008 0.0069
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.011 0.0131 0.0528
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0004 0.0012
Plasmodium falciparum glutathione reductase 0.0081 0.0081 0.11
Leishmania major cAMP-specific phosphodiesterase, putative 0.0044 0.0017 0.0154
Schistosoma mansoni aldehyde dehydrogenase 0.0034 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0007 0.0024
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0081 0.0803
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0059 0.0044 0.0055
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0034 0.0001 0.0001
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0159 0.0216 0.2162
Loa Loa (eye worm) hhat protein 0.0397 0.0625 0.0793
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0089 0.0095 0.0921
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0041 0.0013 0.0118
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0011 0.0041
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0044 0.0017 0.0154
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0052 0.0031 0.0031
Echinococcus multilocularis Aminotransferase class III 0.0089 0.0095 0.0095
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0031 0.004
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0328 0.0508 0.1425
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0014 0.0166
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0017 0.0158
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0294 0.0448 0.1818
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0308 0.0472 0.6175
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0294 0.0448 0.1818
Echinococcus granulosus ubiquitin specific protease 41 0.0308 0.0472 0.06
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.009 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.025 0.0373 0.1513
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0216 0.0874
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0054 0.0069
Mycobacterium ulcerans esterase/lipase LipP 0.0328 0.0508 0.4975
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0041 0.0013 0.0121
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0707 0.116 0.1473
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0625 0.1019 0.1019
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0089 0.0095 0.0921
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0044 0.0017 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0081 0.0081 0.0803
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0089 0.0095 0.0921
Brugia malayi TAR-binding protein 0.0065 0.0054 0.0067
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0014 0.0127
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0009 0.0077
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0384 0.0604 0.0766
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.037 0.058 0.0736
Echinococcus multilocularis 0.0041 0.0013 0.0013
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0044 0.0017 0.002
Brugia malayi Hhat protein 0.0397 0.0625 0.0793
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0004 0.0304
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0397 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.0038
Plasmodium vivax ataxin-2 like protein, putative 0.0127 0.0161 0.241
Loa Loa (eye worm) hypothetical protein 0.011 0.0131 0.0165

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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