Detailed information for compound 556751

Basic information

Technical information
  • TDR Targets ID: 556751
  • Name: 2-aminoacetic acid; (2S)-2-aminopropanoic aci d
  • MW: 164.16 | Formula: C5H12N2O4
  • H donors: 4 H acceptors: 4 LogP: -6.4 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H](C(=O)O)N.NCC(=O)O
  • InChi: 1S/C3H7NO2.C2H5NO2/c1-2(4)3(5)6;3-1-2(4)5/h2H,4H2,1H3,(H,5,6);1,3H2,(H,4,5)/t2-;/m0./s1
  • InChiKey: LTDYEDCDJFHPFI-DKWTVANSSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-aminoacetic acid; (2S)-2-aminopropionic acid
  • 2-aminoethanoic acid; (2S)-2-aminopropanoic acid
  • 2-azanylethanoic acid; (2S)-2-azanylpropanoic acid
  • 27879-92-1
  • 9059-61-4
  • Alanine-glycine polymers
  • Glycine-alanine polymers
  • L-Alanine, polymer with glycine
  • Poly(ala-gly)
  • poly(alanylglycine)

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni synaptotagmin-like protein 0.0023 0.0015 0.0008
Echinococcus granulosus neural cell expressed developmentally 0.0023 0.0015 0.0008
Mycobacterium tuberculosis Conserved protein 0.004 0.0115 0.0233
Trypanosoma cruzi cytoskeleton associated protein, putative 0.0023 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0047 0.0158 0.0367
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0032 0.0066 0.0136
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0047 0.0158 0.0168
Echinococcus multilocularis serine:threonine protein kinase N2 0.0339 0.1932 0.1926
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0058 0.0227 0.2042
Loa Loa (eye worm) C2 domain-containing protein 0.0023 0.0015 0.0017
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.1461 0.1455
Loa Loa (eye worm) hypothetical protein 0.043 0.2483 0.6053
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Echinococcus granulosus nmda type glutamate receptor 0.0032 0.0068 0.0067
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.008 0.0363 0.2794
Echinococcus granulosus glutamate receptor 2 0.0034 0.008 0.0081
Entamoeba histolytica glutamine synthetase, putative 0.0122 0.0613 0.5513
Mycobacterium tuberculosis Probable glutamine synthetase GlnA3 (glutamine synthase) (GS-I) 0.0364 0.2084 0.4219
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0083 0.0167
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.017 0.1338
Brugia malayi RhoGEF domain containing protein 0.0152 0.0795 0.185
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0025 0.0051
Echinococcus granulosus myotubularin protein 13 0.0156 0.0822 0.091
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0023 0.0015 0.0007
Toxoplasma gondii Sma protein 0.0023 0.0015 0.0011
Mycobacterium tuberculosis Probable glutamine synthetase GlnA4 (glutamine synthase) (GS-II) 0.0242 0.1345 0.2722
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0192 0.1042 0.253
Loa Loa (eye worm) raf kinase 0.0152 0.0795 0.1926
Onchocerca volvulus 0.0023 0.0015 0.0028
Toxoplasma gondii ABC1 family protein 0.004 0.0115 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Onchocerca volvulus 0.0053 0.0197 0.0754
Echinococcus granulosus otoferlin 0.0023 0.0015 0.0008
Trypanosoma cruzi cytoskeleton associated protein, putative 0.0023 0.0015 0.0025
Onchocerca volvulus 0.0035 0.0088 0.0321
Trichomonas vaginalis aldo/keto reductase, putative 0.0032 0.0066 0.0511
Entamoeba histolytica protein kinase, putative 0.0192 0.1042 0.9443
Echinococcus granulosus Rac GTPase activating protein 1 0.0152 0.0795 0.0881
Brugia malayi Protein kinase domain containing protein 0.0156 0.0823 0.1916
Mycobacterium tuberculosis Conserved protein 0.004 0.0115 0.0233
Entamoeba histolytica P-glycoprotein-2 0.0058 0.0227 0.1978
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0015 0.0115
Plasmodium falciparum ferlin, putative 0.0023 0.0015 0.0011
Brugia malayi beta-lactamase 0.004 0.0115 0.0253
Echinococcus multilocularis N chimaerin 0.0152 0.0795 0.0788
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0823 0.0912
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.012 0.0947
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0095 0.0305
Onchocerca volvulus 0.0175 0.0936 0.369
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0025 0.002
Trichomonas vaginalis copine, putative 0.0023 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis aldo/keto reductase, putative 0.0032 0.0066 0.0511
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.008 0.0634
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0175 0.0936 0.0929
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 0.008 0.0363 0.2859
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0192 0.1042 0.1035
Echinococcus multilocularis protein piccolo 0.0023 0.0015 0.0007
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0061 0.0247 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Loa Loa (eye worm) C2 domain-containing protein 0.0023 0.0015 0.0017
Schistosoma mansoni diacylglycerol kinase theta 0.0152 0.0795 0.0881
Entamoeba histolytica P-glycoprotein-5 0.0058 0.0227 0.1978
Loa Loa (eye worm) hypothetical protein 0.031 0.1757 0.4277
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0045 0.0091
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0115 0.0233
Echinococcus granulosus hypothetical protein 0.0032 0.0066 0.0065
Entamoeba histolytica hypothetical protein 0.0023 0.0015 0.0028
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0011 0.1631
Brugia malayi glutathione reductase 0.0094 0.0442 0.102
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Loa Loa (eye worm) AGC/AKT protein kinase 0.0197 0.1069 0.2595
Onchocerca volvulus 0.0032 0.0066 0.023
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.012 0.1026
Schistosoma mansoni synaptotagmin 0.0023 0.0015 0.0008
Echinococcus granulosus tyrosine kinase 0.0025 0.0026 0.002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0047 0.0158 0.015
Plasmodium vivax double C2-like domain-containing protein, putative 0.0023 0.0015 0.0011
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0015 0.0008
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Schistosoma mansoni ap endonuclease 0.0023 0.0011 0.0004
Brugia malayi metabotropic glutamate receptor type 2 0.0111 0.0546 0.1265
Schistosoma mansoni rab6-interacting 0.0044 0.0143 0.0152
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.007 0.0556
Entamoeba histolytica aldose reductase, putative 0.0032 0.0066 0.0495
Loa Loa (eye worm) multidrug resistance protein 3 0.0058 0.0227 0.0538
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.0483 0.0532
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Brugia malayi AMP-binding enzyme family protein 0.0049 0.017 0.0381
Echinococcus multilocularis multidrug resistance protein 1 0.0058 0.0227 0.022
Entamoeba histolytica C2 domain containing protein 0.0023 0.0015 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Trypanosoma brucei trypanothione reductase 0.0094 0.0442 0.3485
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0192 0.1042 0.253
Schistosoma mansoni synaptotagmin 0.0023 0.0015 0.0008
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.008 0.0363 0.3321
Echinococcus granulosus Polycystic kidney disease protein 0.0044 0.0143 0.0152
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Brugia malayi steroid hormone receptor 0.0047 0.0158 0.0352
Trypanosoma cruzi synaptotagmin, putative 0.0023 0.0015 0.0025
Echinococcus multilocularis nmda type glutamate receptor 0.0032 0.0068 0.006
Loa Loa (eye worm) hypothetical protein 0.0129 0.0659 0.1593
Onchocerca volvulus 0.0032 0.0066 0.023
Echinococcus granulosus multidrug resistance protein 1 0.0041 0.0121 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0115 0.0826
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.007 0.0216
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Schistosoma mansoni hypothetical protein 0.0023 0.0015 0.0008
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.008 0.0073
Schistosoma mansoni lipoxygenase 0.0198 0.1078 0.1197
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.012 0.0864
Echinococcus multilocularis synaptotagmin 0.0023 0.0015 0.0007
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0023 0.0015 0.0007
Toxoplasma gondii hypothetical protein 0.0023 0.0015 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0015 0.0025
Schistosoma mansoni hypothetical protein 0.0084 0.0382 0.0419
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0047 0.0158 0.0367
Trichomonas vaginalis esterase, putative 0.004 0.0115 0.0982
Echinococcus multilocularis peregrin 0.003 0.0058 0.005
Loa Loa (eye worm) hypothetical protein 0.0049 0.017 0.0396
Brugia malayi Thioredoxin reductase 0.0094 0.0442 0.102
Giardia lamblia PHD finger protein 15 0.003 0.0058 0.8224
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0025 0.002
Schistosoma mansoni loxhd1 0.0044 0.0143 0.0152
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Schistosoma mansoni inositol monophosphatase 0.0036 0.009 0.0093
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis synaptotagmin 1,2, putative 0.0023 0.0015 0.0029
Trypanosoma cruzi aldo-keto reductase 0.0032 0.0066 0.043
Echinococcus granulosus C2 calcium lipid binding region CaLB 0.0023 0.0015 0.0008
Brugia malayi ABC transporter family protein 0.0058 0.0227 0.0516
Trichomonas vaginalis aldo/keto reductase, putative 0.0032 0.0066 0.0511
Echinococcus granulosus cpg binding protein 0.0062 0.0251 0.0273
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.007 0.0556
Trichomonas vaginalis splicing factor 3A subunit, putative 0.0023 0.0015 0.0029
Schistosoma mansoni retinoic acid receptor RXR 0.0047 0.0158 0.0168
Mycobacterium ulcerans glutamine synthetase 0.0472 0.2739 0.5534
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.007 0.0285
Onchocerca volvulus 0.0023 0.0015 0.0028
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0047 0.0158 0.0168
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0023 0.0015 0.0017
Onchocerca volvulus 0.0285 0.1607 0.6355
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0058 0.0227 0.022
Schistosoma mansoni rab6-interacting 0.0044 0.0143 0.0152
Mycobacterium leprae Probable lipase LipE 0.004 0.0115 0.0214
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0058 0.0227 0.0791
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0032 0.0066 0.0136
Brugia malayi Synaptotagmin protein 3 0.0023 0.0015 0.0017
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0213 0.117 0.2368
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0058 0.017
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0115 0.0233
Onchocerca volvulus Matrilysin homolog 0.0038 0.0101 0.0373
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.017 0.0321
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0047 0.0158 0.0352
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0032 0.0066 0.0517
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0795 0.0881
Leishmania major prostaglandin f synthase, putative 0.0032 0.0066 0.0517
Schistosoma mansoni atypical protein kinase C 0.0573 0.3355 0.3743
Loa Loa (eye worm) hypothetical protein 0.0036 0.0095 0.0213
Loa Loa (eye worm) C2 domain-containing protein 0.0023 0.0015 0.0017
Loa Loa (eye worm) oxidoreductase 0.0032 0.0066 0.0142
Schistosoma mansoni hypothetical protein 0.0152 0.0795 0.0881
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0023 0.0015 0.0008
Echinococcus multilocularis multidrug resistance protein 1 0.0058 0.0227 0.022
Plasmodium vivax hypothetical protein, conserved 0.003 0.0058 0.017
Echinococcus multilocularis protein kinase c epsilon type 0.0514 0.2995 0.299
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Brugia malayi Inositol-1 0.0036 0.009 0.0194
Brugia malayi Hemopexin family protein 0.0024 0.0019 0.0027
Onchocerca volvulus 0.004 0.0115 0.0428
Echinococcus granulosus aldo keto reductase 0.0032 0.0066 0.0065
Echinococcus granulosus serine:threonine protein kinase N2 0.0151 0.0792 0.0877
Schistosoma mansoni hypothetical protein 0.0117 0.0582 0.0643
Brugia malayi nuclear hormone receptor 0.0047 0.0158 0.0352
Schistosoma mansoni protein kinase C mu 0.0152 0.0795 0.0881
Brugia malayi C1-like domain containing protein 0.0286 0.1609 0.376
Leishmania major copine i-like protein 0.0023 0.0015 0.0115
Loa Loa (eye worm) hypothetical protein 0.0202 0.1103 0.2679
Leishmania major hypothetical protein, conserved 0.0023 0.0015 0.0115
Brugia malayi ecdysteroid receptor 0.0047 0.0158 0.0352
Schistosoma mansoni rabphilin-3a 0.0023 0.0015 0.0008
Toxoplasma gondii hypothetical protein 0.0023 0.0015 0.0011
Echinococcus multilocularis multidrug resistance protein 1 0.0041 0.0121 0.0113
Brugia malayi multidrug resistance protein 3 0.0058 0.0227 0.0516
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0058 0.0227 0.022
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.012 0.0947
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) 0.008 0.0363 0.0734
Echinococcus multilocularis serine threonine protein kinase 0.0759 0.4485 0.448
Schistosoma mansoni tyrosine kinase 0.0025 0.0026 0.002
Plasmodium vivax multidrug resistance protein 1, putative 0.0058 0.0227 0.0791
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0152 0.0795 0.0881
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0015 0.0025
Plasmodium vivax glutathione reductase, putative 0.0094 0.0442 0.1578
Schistosoma mansoni hypothetical protein 0.0024 0.0019 0.0013
Echinococcus granulosus multiple C2 and transmembrane domain containing protein 0.0023 0.0015 0.0008
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.007 0.0469
Echinococcus granulosus GPCR family 3 C terminal 0.0035 0.0088 0.009
Brugia malayi Muscleblind-like protein 0.031 0.1757 0.4108
Brugia malayi hypothetical protein 0.0261 0.1461 0.3414
Loa Loa (eye worm) hypothetical protein 0.0036 0.0095 0.0213
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0834 0.494 1
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0115 0.0982
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.004 0.0118 0.0123
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0115 0.0233
Onchocerca volvulus 0.0436 0.2524 1
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0286 0.1609 0.3916
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0083 0.0167
Plasmodium falciparum ferlin, putative 0.0023 0.0015 0.0011
Echinococcus multilocularis UNCoordinated family member (unc 13) 0.0023 0.0015 0.0007
Onchocerca volvulus 0.0023 0.0015 0.0028
Toxoplasma gondii Elicitor-responsive protein, putative 0.0023 0.0015 0.0011
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0143 0.0152
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0115 0.0982
Onchocerca volvulus 0.0023 0.0015 0.0028
Echinococcus multilocularis raf serine:threonine protein kinase 0.0152 0.0795 0.0788
Entamoeba histolytica P-glycoprotein-1 0.0058 0.0227 0.1978
Brugia malayi NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor 0.008 0.0363 0.0834
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0158 0.0352
Brugia malayi diacylglycerol kinase 0.0152 0.0795 0.185
Echinococcus multilocularis C2 calcium lipid binding region, CaLB 0.0023 0.0015 0.0007
Leishmania major phospholipase c-like protein 0.0023 0.0015 0.0115
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0025 0.0026 0.0045
Schistosoma mansoni inositol monophosphatase 0.0036 0.009 0.0093
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0023 0.0013 0.0027
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0358 0.2756
Brugia malayi beta-lactamase family protein 0.004 0.0115 0.0253
Echinococcus multilocularis muscleblind protein 0.031 0.1757 0.175
Onchocerca volvulus 0.0049 0.017 0.0644
Echinococcus granulosus synaptotagmin 0.0023 0.0015 0.0008
Echinococcus multilocularis multiple C2 and transmembrane domain containing protein 0.0023 0.0015 0.0007
Echinococcus granulosus dnaJ subfamily B 0.0423 0.2442 0.2723
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0237 0.1315 0.2646
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0047 0.0158 0.0168
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.007 0.0556
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0047 0.0158 0.0352
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0058 0.017
Schistosoma mansoni cpg binding protein 0.0062 0.0251 0.0273
Trichomonas vaginalis synaptotagmin, putative 0.0023 0.0015 0.0029
Echinococcus multilocularis synaptotagmin 0.0023 0.0015 0.0007
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0025 0.0018
Echinococcus granulosus active breakpoint cluster region 0.0023 0.0015 0.0008
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0156 0.0823 0.0816
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0024 0.0018
Toxoplasma gondii diacylglycerol kinase, putative 0.0152 0.0795 0.2873
Brugia malayi Matrixin family protein 0.0041 0.0122 0.0269
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0181 0.0407
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0156 0.0824 0.0817
Echinococcus multilocularis nmda type glutamate receptor 0.0025 0.0026 0.0018
Entamoeba histolytica hypothetical protein 0.0117 0.0582 0.523
Brugia malayi RhoGAP domain containing protein 0.0152 0.0795 0.185
Mycobacterium ulcerans proteasome PrcA 0.0834 0.494 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0025 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0158 0.0352
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0047 0.0158 0.0367
Loa Loa (eye worm) oxidoreductase 0.0032 0.0066 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.012 0.0947
Brugia malayi phospholipase C homolog 0.0023 0.0015 0.0017
Echinococcus granulosus multidrug resistance protein 1 0.0041 0.0121 0.0126
Echinococcus multilocularis protein kinase c iota type 0.0557 0.326 0.3255
Loa Loa (eye worm) matrixin family protein 0.0041 0.0122 0.028
Loa Loa (eye worm) hypothetical protein 0.0035 0.0084 0.0186
Echinococcus granulosus calpain 5 0.0023 0.0015 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0047 0.0158 0.0352
Mycobacterium tuberculosis Probable reductase 0.0213 0.117 0.2368
Schistosoma mansoni glutamine synthetase bacteria 0.0364 0.2084 0.2323
Echinococcus multilocularis muscleblind protein 1 0.031 0.1757 0.175
Echinococcus multilocularis synaptotagmin 0.0023 0.0015 0.0007
Mycobacterium ulcerans hypothetical protein 0.004 0.0115 0.0211
Giardia lamblia Aldose reductase 0.0032 0.0066 0.9295
Brugia malayi Receptor family ligand binding region containing protein 0.006 0.0241 0.0547
Mycobacterium tuberculosis Conserved hypothetical protein 0.0242 0.1345 0.2722
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0047 0.0158 0.0168
Loa Loa (eye worm) hypothetical protein 0.01 0.0483 0.1164
Trypanosoma brucei prostaglandin f synthase 0.0032 0.0066 0.0517
Echinococcus multilocularis glutamate receptor 2 0.0034 0.008 0.0073
Brugia malayi protein kinase C II. 0.0514 0.2995 0.7016
Plasmodium falciparum glutathione reductase 0.0094 0.0442 0.1578
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0025 0.0051
Echinococcus multilocularis cpg binding protein 0.0062 0.0251 0.0244
Trichomonas vaginalis vab10 spectraplakin, putative 0.0023 0.0015 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0911 0.5406 0.6038
Brugia malayi PAS domain containing protein 0.0048 0.0164 0.0367
Trichomonas vaginalis synaptotagmin, putative 0.0023 0.0015 0.0029
Mycobacterium tuberculosis Probable oxidoreductase 0.0237 0.1315 0.2661
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.007 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0143 0.0136
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.008 0.0363 0.0397
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0024 0.0038
Loa Loa (eye worm) NADH-ubiquinone oxidoreductase 51 kDa subunit 0.008 0.0363 0.0868
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.008 0.0073
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0047 0.0158 0.0168
Leishmania major extracellular receptor, putative 0.0025 0.0026 0.0204
Loa Loa (eye worm) hypothetical protein 0.0436 0.2524 0.6155
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.007 0.0216
Toxoplasma gondii aldose reductase, putative 0.0032 0.0066 0.0198
Trichomonas vaginalis AGC family protein kinase 0.0197 0.1069 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0058 0.0227 0.2042
Loa Loa (eye worm) hypothetical protein 0.0695 0.4097 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.012 0.1026
Echinococcus multilocularis GPCR, family 3, C terminal 0.0035 0.0088 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0039
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0834 0.494 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0047 0.0158 0.0352
Schistosoma mansoni lipoxygenase 0.0118 0.0592 0.0653
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0025 0.0201
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.008 0.0363 0.2794
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.0047 0.0158 0.0367
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.007 0.0556
Onchocerca volvulus Putative cc2d1b protein 0.0023 0.0015 0.0028
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0011 0.001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0231 0.0546
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.013 0.0123
Loa Loa (eye worm) hypothetical protein 0.0047 0.0158 0.0367
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.012 0.0864
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0273 0.153 0.1523
Echinococcus granulosus single minded 2 0.0035 0.0088 0.009
Leishmania major NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.008 0.0363 0.2859
Echinococcus granulosus myoferlin 0.0023 0.0015 0.0008
Mycobacterium tuberculosis Glutamine synthetase GlnA1 (glutamine synthase) (GS-I) 0.0242 0.1345 0.2722
Trichomonas vaginalis Proline-rich protein, putative 0.0023 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0175 0.0936 0.2271
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0032 0.0066 0.0113
Trichomonas vaginalis AGC family protein kinase 0.0197 0.1069 1
Loa Loa (eye worm) copine family protein 0.0023 0.0015 0.0017
Onchocerca volvulus Alhambra homolog 0.003 0.0058 0.02
Loa Loa (eye worm) jmjC domain-containing protein 0.0097 0.0464 0.1115
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0039
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.0358 0.0822
Echinococcus granulosus dna polymerase kappa 0.0041 0.012 0.0126
Entamoeba histolytica hypothetical protein 0.0152 0.0795 0.718
Entamoeba histolytica hypothetical protein 0.0028 0.0045 0.0308
Echinococcus granulosus extended synaptotagmin 2 0.0023 0.0015 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0192 0.1042 0.1157
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0045
Leishmania major c2 domain protein, putative 0.0023 0.0015 0.0115
Echinococcus granulosus NADH dehydrogenase ubiquinone flavoprotein 1 0.008 0.0363 0.0397
Leishmania major hypothetical protein, conserved 0.004 0.0115 0.0909
Echinococcus multilocularis intersectin 2 0.0023 0.0015 0.0007
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.008 0.0081
Loa Loa (eye worm) hypothetical protein 0.0031 0.006 0.0129
Loa Loa (eye worm) hypothetical protein 0.0129 0.0659 0.1593
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0087 0.0401 0.0963
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0047 0.0158 0.0367
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0044
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.009 0.0712
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.007 0.0216
Brugia malayi CHE-14 protein 0.0087 0.0401 0.0924
Loa Loa (eye worm) hypothetical protein 0.004 0.0115 0.0263
Brugia malayi p70 ribosomal S6 kinase beta 0.0192 0.1042 0.243
Onchocerca volvulus 0.01 0.0483 0.1891
Brugia malayi hypothetical protein 0.0117 0.0582 0.135
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0066 0.0065
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.007 0.0063
Entamoeba histolytica Rap/Ran GTPase activating protein, putative 0.0023 0.0015 0.0028
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.017 0.0324
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0045
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.009 0.0722
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0025 0.002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.0551 0.1976
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.006 0.0474
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0026 0.0045
Brugia malayi jmjC domain containing protein 0.0025 0.0025 0.0042
Onchocerca volvulus 0.0032 0.0066 0.023
Loa Loa (eye worm) AGC/PKN protein kinase 0.0192 0.1042 0.253
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0158 0.0352
Echinococcus multilocularis protein dispatched 1 0.0099 0.0476 0.0469
Brugia malayi Synapse defective protein 1 0.0023 0.0015 0.0017
Trichomonas vaginalis synaptotagmin, putative 0.0023 0.0015 0.0029
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0045 0.0068
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0015 0.0028
Schistosoma mansoni synaptotagmin 0.0023 0.0015 0.0008
Echinococcus multilocularis copine 9 0.0023 0.0015 0.0007
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0058 0.0227 0.0246
Echinococcus granulosus synaptotagmin 0.0023 0.0015 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0158 0.015
Loa Loa (eye worm) hypothetical protein 0.0047 0.0158 0.0367
Onchocerca volvulus 0.0044 0.0143 0.0539
Onchocerca volvulus 0.004 0.0115 0.0428
Echinococcus granulosus UNCoordinated family member unc 13 0.0023 0.0015 0.0008
Echinococcus granulosus Niemann Pick C1 protein 0.0289 0.1631 0.1815
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0152 0.0795 0.0881
Loa Loa (eye worm) hypothetical protein 0.0058 0.0223 0.0528
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.007 0.0469
Brugia malayi Synaptotagmin I 0.0023 0.0015 0.0017
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.007 0.0216
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0248 0.1378 0.1532
Brugia malayi jmjC domain containing protein 0.0025 0.0025 0.0042
Echinococcus multilocularis FTZ F1 alpha 0.0047 0.0158 0.015
Onchocerca volvulus 0.0047 0.0158 0.0596
Echinococcus multilocularis sterol regulatory element binding protein 0.0087 0.0401 0.0394
Brugia malayi AMP-binding enzyme family protein 0.0049 0.017 0.0381
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0045 0.0355
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0045 0.0071
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Brugia malayi NEDD4.2 0.0023 0.0015 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Onchocerca volvulus 0.0281 0.1581 0.625
Loa Loa (eye worm) glutathione reductase 0.0094 0.0442 0.1062
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.017 0.1449
Echinococcus multilocularis synaptotagmin 2 0.0023 0.0015 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.009 0.0745
Mycobacterium ulcerans beta-lactamase 0.004 0.0115 0.0211
Mycobacterium ulcerans glutamine synthetase GlnA1 0.0472 0.2739 0.5534
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0023 0.0015 0.0007
Trypanosoma brucei unspecified product 0.0034 0.008 0.0634
Schistosoma mansoni nedd-4-like E3 ubiquitin-protein ligase 0.0023 0.0015 0.0008
Schistosoma mansoni synaptic ras gtpase activating protein syngap 0.0023 0.0015 0.0008
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0058 0.0227 0.022
Plasmodium vivax ferlin, putative 0.0023 0.0015 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0823 0.0912
Schistosoma mansoni pol-related 0.0032 0.0066 0.0065
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0023 0.0013 0.0003
Echinococcus granulosus protein kinase C gamma type 0.0759 0.4485 0.5007
Schistosoma mansoni jumonji/arid domain-containing protein 0.0097 0.0464 0.051
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0066 0.0065
Echinococcus multilocularis synaptotagmin protein 4 0.0023 0.0015 0.0007
Entamoeba histolytica protein kinase, putative 0.0197 0.1069 0.9685
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0023 0.0015 0.0011
Onchocerca volvulus 0.0025 0.0026 0.0073
Loa Loa (eye worm) glutamate receptor 0.0086 0.0394 0.0945
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.007 0.0216
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0023 0.0015 0.0008
Loa Loa (eye worm) C2 domain-containing protein 0.0023 0.0015 0.0017
Entamoeba histolytica hypothetical protein 0.0023 0.0015 0.0028
Schistosoma mansoni protein kinase C 0.0175 0.0936 0.1039
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.007 0.0216
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Echinococcus granulosus synaptotagmin 15 0.0023 0.0015 0.0008
Echinococcus granulosus metabotropic glutamate receptor 2 0.0187 0.101 0.1121
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0015 0.0025
Schistosoma mansoni steroid hormone receptor ad4bp 0.0047 0.0158 0.0168
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0032 0.0068 0.006
Loa Loa (eye worm) doublecortin family protein 0.0044 0.0143 0.0332
Loa Loa (eye worm) hypothetical protein 0.0051 0.0181 0.0424
Brugia malayi jmjC domain containing protein 0.0025 0.0025 0.0042
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0213 0.117 0.2368
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0045 0.0123
Onchocerca volvulus 0.043 0.2483 0.9835
Schistosoma mansoni synaptotagmin 12 0.0023 0.0015 0.0008
Entamoeba histolytica hypothetical protein 0.0117 0.0582 0.523
Trypanosoma cruzi cAMP binding protein, putative 0.0023 0.0015 0.0025
Entamoeba histolytica DENN domain protein 0.0023 0.0015 0.0028
Trypanosoma cruzi synaptotagmin, putative 0.0023 0.0015 0.0025
Echinococcus multilocularis aldo keto reductase 0.0032 0.0066 0.0058
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0068 0.0137
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0035 0.0088 0.0189
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0083 0.0167
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0025 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Mycobacterium tuberculosis Probable dehydrogenase 0.0213 0.117 0.2368
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0115 0.0233
Loa Loa (eye worm) hypothetical protein 0.0044 0.0143 0.0332
Entamoeba histolytica C2 domain containing protein 0.0023 0.0015 0.0028
Loa Loa (eye worm) hypothetical protein 0.0281 0.1581 0.3847
Schistosoma mansoni serine/threonine protein kinase 0.0192 0.1042 0.1157
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0158 0.0168
Loa Loa (eye worm) hypothetical protein 0.043 0.2483 0.6053
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0023 0.0015 0.0007
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0025 0.002
Schistosoma mansoni synaptotagmin 0.0023 0.0015 0.0008
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0058 0.0227 0.2042
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0192 0.1042 0.253
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0018 0.0025
Echinococcus multilocularis glutamate receptor 2 0.0025 0.0026 0.0018
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0058 0.0227 0.0791
Entamoeba histolytica P-glycoprotein-2, putative 0.0058 0.0227 0.1978
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0024 0.0018
Echinococcus granulosus sterol regulatory element binding protein 0.0087 0.0401 0.044
Trichomonas vaginalis ABC transporter, putative 0.0058 0.0227 0.2042
Onchocerca volvulus 0.0025 0.0026 0.0073
Loa Loa (eye worm) hypothetical protein 0.004 0.0115 0.0263
Loa Loa (eye worm) synaptotagmin-1 0.0023 0.0015 0.0017
Schistosoma mansoni rac gtpase activating protein 0.0152 0.0795 0.0881
Brugia malayi Cytochrome P450 family protein 0.0026 0.003 0.0052
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0023 0.0015 0.0008
Brugia malayi Receptor family ligand binding region containing protein 0.0025 0.0026 0.0043
Echinococcus granulosus protein kinase c iota type 0.0557 0.326 0.3637
Loa Loa (eye worm) beta-lactamase 0.004 0.0115 0.0263
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0254 0.0604
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0058 0.0227 0.2042
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Schistosoma mansoni otoferlin 0.0023 0.0015 0.0008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0197 0.0446
Echinococcus granulosus multidrug resistance protein 1 0.0058 0.0227 0.0246
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0026 0.0045
Echinococcus granulosus C2 calcium lipid binding region CaLB 0.0023 0.0015 0.0008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.009 0.0289
Plasmodium falciparum phd finger protein, putative 0.003 0.0058 0.017
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0041 0.0121 0.1031
Echinococcus granulosus synaptotagmin 0.0023 0.0015 0.0008
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0058 0.0123
Brugia malayi jmjC domain containing protein 0.0156 0.0824 0.1917
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0058 0.0227 0.2042
Mycobacterium leprae conserved hypothetical protein 0.004 0.0115 0.0214
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0068 0.0117
Echinococcus granulosus ecdysone induced protein 78C 0.0047 0.0158 0.0168
Echinococcus granulosus unc 13 munc13 0.0175 0.0936 0.1039
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0025 0.002
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0206 0.1122 0.1246
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.017 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0202 0.1103 1
Entamoeba histolytica C2 domain containing protein 0.0023 0.0015 0.0028
Entamoeba histolytica protein kinase, putative 0.0197 0.1069 0.9685
Echinococcus granulosus lysine specific demethylase 5A 0.0097 0.0464 0.051
Brugia malayi nuclear receptor RXR 0.0025 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0629 0.3693 0.9013
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0011 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0047 0.0158 0.0352
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0237 0.1315 0.2661
Schistosoma mansoni serine/threonine protein kinase 0.0192 0.1042 0.1157
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0154 0.0164
Echinococcus multilocularis Rac GTPase activating protein 1 0.0152 0.0795 0.0788
Onchocerca volvulus NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial homolog 0.0043 0.0136 0.0509
Trichomonas vaginalis abcb9, putative 0.0058 0.0227 0.2042
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0142
Schistosoma mansoni aldo-keto reductase 0.0032 0.0066 0.0065
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0024 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0197 0.1069 1
Schistosoma mansoni cpg binding protein 0.0062 0.0251 0.0273
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0047 0.0158 0.0596
Echinococcus granulosus synaptotagmin 2 0.0023 0.0015 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.007 0.0469
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.007 0.0143
Leishmania major hypothetical protein, conserved 0.0023 0.0015 0.0115
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0123
Plasmodium falciparum multidrug resistance protein 1 0.0058 0.0227 0.0791
Toxoplasma gondii hypothetical protein 0.017 0.0907 0.3282
Loa Loa (eye worm) hypothetical protein 0.0285 0.1607 0.3912
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0058 0.0227 0.1793
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0187 0.101 0.1003
Schistosoma mansoni fer-1-related 0.0023 0.0015 0.0008
Echinococcus multilocularis myotubularin protein 13 0.0156 0.0822 0.0815
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0047 0.0158 0.0367
Echinococcus granulosus protein kinase c epsilon type 0.0514 0.2995 0.3341
Echinococcus multilocularis synaptotagmin 0.0023 0.0015 0.0007
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0084 0.0178
Onchocerca volvulus 0.0023 0.0015 0.0028
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.007 0.0558
Entamoeba histolytica hypothetical protein 0.0023 0.0015 0.0028
Trypanosoma brucei rac serine-threonine kinase, putative 0.0197 0.1069 0.8429
Echinococcus multilocularis ATP binding cassette sub family B 0.0058 0.0223 0.0216
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0164 0.0175
Loa Loa (eye worm) hypothetical protein 0.0273 0.153 0.3723
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0045
Echinococcus multilocularis Niemann Pick C1 protein 0.0289 0.1631 0.1624
Mycobacterium ulcerans NADH dehydrogenase I subunit F 0.008 0.0363 0.0712
Loa Loa (eye worm) oxidoreductase 0.0032 0.0066 0.0142
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0015 0.0025
Plasmodium vivax ferlin, putative 0.0023 0.0015 0.0011
Trypanosoma brucei C2 domain containing protein, putative 0.0023 0.0015 0.0115
Schistosoma mansoni Mername-AA248 (C02 family) 0.0023 0.0015 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Trichomonas vaginalis Circumsporozoite protein precursor, putative 0.0023 0.0015 0.0029
Schistosoma mansoni serine/threonine kinase 0.0192 0.1042 0.1157
Loa Loa (eye worm) hypothetical protein 0.0152 0.0795 0.1926
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.017 0.1449
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0045
Brugia malayi LD23056p 0.0023 0.0015 0.0017
Echinococcus granulosus intersectin 2 0.0023 0.0015 0.0008
Giardia lamblia Aldose reductase 0.0032 0.0066 0.9295
Loa Loa (eye worm) hypothetical protein 0.0035 0.0088 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0015 0.0011
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.007 0.007
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0034 0.008 0.0073
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.017 0.1338
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0058 0.0227 0.2042
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Echinococcus multilocularis tyrosine kinase 0.0025 0.0026 0.0018
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0011 0.0091
Loa Loa (eye worm) hypothetical protein 0.016 0.0848 0.2054
Loa Loa (eye worm) RasGEF domain-containing protein 0.0152 0.0795 0.1926
Trypanosoma cruzi trypanothione reductase, putative 0.0094 0.0442 0.3425
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0023 0.0015 0.0008
Onchocerca volvulus Glutamine synthetase homolog 0.023 0.1268 0.5007
Echinococcus granulosus raf serine:threonine protein kinase 0.0152 0.0795 0.0881
Trichomonas vaginalis glutamine synthetase-bacteria, putative 0.0122 0.0613 0.5692
Echinococcus multilocularis copine 9 0.0023 0.0015 0.0007
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0152 0.0795 0.0881
Schistosoma mansoni hypothetical protein 0.0053 0.0197 0.0212
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Plasmodium falciparum double C2-like domain-containing protein 0.0023 0.0015 0.0011
Echinococcus granulosus muscleblind protein 0.031 0.1757 0.1956
Trichomonas vaginalis synaptotagmin 1,2, putative 0.0023 0.0015 0.0029
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0011 0.0023
Mycobacterium tuberculosis Probable glutamine synthetase GlnA2 (glutamine synthase) (GS-II) 0.0472 0.2739 0.5544
Echinococcus multilocularis protein kinase c eta type 0.0152 0.0795 0.0788
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0772 0.187
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0025 0.0018
Echinococcus multilocularis ecdysone induced protein 78C 0.0047 0.0158 0.015
Loa Loa (eye worm) hypothetical protein 0.006 0.0241 0.057
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0023 0.0013 0.0286
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0181 0.0407
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase I subunit F 0.008 0.0363 0.1693
Entamoeba histolytica hypothetical protein 0.0023 0.0015 0.0028
Trypanosoma brucei glutamine synthetase, putative 0.023 0.1268 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0143 0.0152
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Schistosoma mansoni protein kinase C mu 0.0286 0.1609 0.1791
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.012 0.0947
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0032 0.0066 0.0511
Echinococcus granulosus microtubule associated protein 2 0.1494 0.895 1
Onchocerca volvulus 0.0058 0.0227 0.0873
Leishmania major hypothetical protein, conserved 0.0023 0.0015 0.0115
Schistosoma mansoni patched 1 0.0087 0.0401 0.044
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0115 0.012
Loa Loa (eye worm) hypothetical protein 0.004 0.0115 0.0263
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0032 0.0066 0.0511
Trichomonas vaginalis ion channel nompc, putative 0.0023 0.0015 0.0029
Trichomonas vaginalis synaptotagmin, putative 0.0023 0.0015 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0083 0.0167
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0192 0.1042 0.1157
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Schistosoma mansoni lozenge 0.0054 0.0201 0.0216
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.0358 0.0392
Schistosoma mansoni metabotropic glutamate receptor 0.0111 0.0546 0.0602
Entamoeba histolytica protein kinase, putative 0.0028 0.0043 0.0286
Brugia malayi Protein kinase domain containing protein 0.0192 0.1042 0.243
Trypanosoma cruzi aldo/keto reductase, putative 0.0032 0.0066 0.043
Echinococcus granulosus Protein patched homolog 1 0.0087 0.0401 0.044
Brugia malayi WW domain containing protein 0.0023 0.0015 0.0017
Brugia malayi protein kinase C3,putative 0.037 0.2119 0.4959
Brugia malayi CXXC zinc finger family protein 0.0059 0.0231 0.0524
Echinococcus multilocularis Diacylglycerol kinase theta 0.0152 0.0795 0.0788
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, putative 0.008 0.0363 0.2859
Loa Loa (eye worm) hypothetical protein 0.0588 0.3446 0.8409
Trypanosoma cruzi Coiled-coil and C2 domain-containing protein 0.0023 0.0015 0.0025
Plasmodium vivax glutamine synthetase, putative 0.0472 0.2739 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.007 1
Brugia malayi hypothetical protein 0.0044 0.0143 0.0319
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.007 0.0556
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.007 0.0469
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0213 0.117 0.2368
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0158 0.0168
Toxoplasma gondii glutamine synthetase, type I, putative 0.0472 0.2739 1
Loa Loa (eye worm) hypothetical protein 0.031 0.1757 0.4277
Leishmania major hypothetical protein, conserved 0.0023 0.0015 0.0115
Echinococcus multilocularis multiple C2 and transmembrane domain containing protein 0.0023 0.0015 0.0007
Plasmodium vivax JmjC domain containing protein 0.0025 0.0025 0.0051
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0043 0.0083
Schistosoma mansoni polycystin 1-related 0.0044 0.0143 0.0152
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0058 0.0227 0.022
Entamoeba histolytica glutamine synthetase, putative 0.0122 0.0613 0.5513
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0358 0.2822
Trichomonas vaginalis taga, putative 0.0058 0.0227 0.2042
Entamoeba histolytica C2 domain containing protein 0.0023 0.0015 0.0028
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0025 0.0018
Entamoeba histolytica hypothetical protein 0.0023 0.0015 0.0028
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.007 0.012
Schistosoma mansoni hypothetical protein 0.0023 0.0015 0.0008
Entamoeba histolytica protein kinase, putative 0.0028 0.0043 0.0286
Brugia malayi Pleckstrin Homology Domain 0.0156 0.0822 0.1912
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0011 0.0091
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0025 0.0026 0.0043
Loa Loa (eye worm) steroid hormone receptor 0.0047 0.0158 0.0367
Echinococcus multilocularis C2 calcium lipid binding region, CaLB 0.0023 0.0015 0.0007
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.007 0.0556
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.003 0.0054
Trypanosoma brucei synaptotagmin, putative 0.0023 0.0015 0.0115
Loa Loa (eye worm) hypothetical protein 0.0261 0.1461 0.3555
Brugia malayi Bromodomain containing protein 0.003 0.0058 0.0118
Trichomonas vaginalis synaptotagmin 1,2, putative 0.0023 0.0015 0.0029
Trichomonas vaginalis ABC transporter, putative 0.0058 0.0227 0.2042
Brugia malayi hypothetical protein 0.0025 0.0024 0.0038
Trichomonas vaginalis AGC family protein kinase 0.0197 0.1069 1
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0015 0.0025
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0115 0.0233
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0158 0.0168
Trichomonas vaginalis ABC transporter, putative 0.0058 0.0227 0.2042
Entamoeba histolytica C2 domain containing protein 0.0023 0.0015 0.0028
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Schistosoma mansoni multidrug resistance protein 0.0058 0.0227 0.0246
Echinococcus granulosus RUN 0.0044 0.0143 0.0152
Loa Loa (eye worm) hypothetical protein 0.0036 0.0095 0.0213
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.008 0.0081
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0023 0.0015 0.0008
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0198 0.1078 0.1071
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0058 0.0227 0.0246
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0058 0.0227 0.2042
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0631 0.0698
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0192 0.1042 0.253
Loa Loa (eye worm) oxidoreductase 0.0032 0.0066 0.0142
Brugia malayi Synapse defective protein 1 0.0023 0.0015 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.012 0.0947
Schistosoma mansoni serine/threonine protein kinase 0.0514 0.2995 0.3341
Schistosoma mansoni smdr2 0.0058 0.0227 0.0246
Trichomonas vaginalis AGC family protein kinase 0.0197 0.1069 1
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0058 0.0227 0.046
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0049 0.017 0.0396
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0058 0.0227 0.2042
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0025 0.0026 0.0073
Loa Loa (eye worm) oxidoreductase 0.0032 0.0066 0.0142
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.012 0.0864
Schistosoma mansoni microtubule-associated protein tau 0.1494 0.895 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.017 0.0321
Brugia malayi hypothetical protein 0.016 0.0848 0.1973
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0385 0.2214 0.5397
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Echinococcus granulosus protein kinase c eta type 0.0152 0.0795 0.0881
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0058 0.0227 0.2042
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0045 0.0123
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0023 0.0015 0.0008
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0134 0.0687 0.1662
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0115 0.0909
Entamoeba histolytica diacylglycerol kinase, putative 0.0152 0.0795 0.718
Echinococcus granulosus FTZ F1 alpha 0.0047 0.0158 0.0168
Loa Loa (eye worm) thioredoxin reductase 0.0094 0.0442 0.1062
Echinococcus granulosus phd:f box containing protein 0.0025 0.0025 0.002
Leishmania major hypothetical protein, conserved 0.0023 0.0015 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0115 0.0982
Plasmodium vivax multidomain scavenger receptor, putative 0.0044 0.0143 0.0483
Entamoeba histolytica hypothetical protein 0.0025 0.0026 0.0131
Schistosoma mansoni jumonji/arid domain-containing protein 0.0097 0.0464 0.051
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.006 0.0241 0.057
Trypanosoma brucei C2 domain containing protein, putative 0.0023 0.0015 0.0115
Brugia malayi Hr1 repeat family protein 0.0192 0.1042 0.243
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0045 0.0355
Leishmania major c2 domain protein, putative 0.0023 0.0015 0.0115
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.009 0.0712
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis copine, putative 0.0023 0.0015 0.0029
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0025 0.0044
Onchocerca volvulus 0.0032 0.0066 0.023
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0025 0.002
Trypanosoma brucei C2 domain/Ankyrin repeats (3 copies), putative 0.0023 0.0015 0.0115
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0066 0.0065
Echinococcus multilocularis unc 13 (munc13) 0.0175 0.0936 0.0929
Brugia malayi photoreceptor-specific nuclear receptor 0.0047 0.0158 0.0352
Echinococcus granulosus N chimaerin 0.0152 0.0795 0.0881
Toxoplasma gondii ferlin family protein 0.0023 0.0015 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0049 0.017 0.0381
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Trypanosoma cruzi C2 domain containing protein, putative 0.0023 0.0015 0.0025
Entamoeba histolytica aldose reductase, putative 0.0032 0.0066 0.0495
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.009 0.0745
Brugia malayi hypothetical protein 0.0025 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.017 0.0321
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.012 0.0947
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0023 0.0015 0.0029
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0025 0.0051
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0015 0.0025
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.006 0.0241 0.057
Entamoeba histolytica hypothetical protein 0.0117 0.0582 0.523
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.017 0.0321
Loa Loa (eye worm) hypothetical protein 0.0047 0.0158 0.0367
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0115 0.012
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0058 0.0227 0.0246
Echinococcus multilocularis myoferlin 0.0023 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0152 0.0795 0.1926
Loa Loa (eye worm) hypothetical protein 0.017 0.0907 0.2199
Loa Loa (eye worm) hypothetical protein 0.0436 0.2524 0.6155
Loa Loa (eye worm) runx1 0.0054 0.0201 0.0473
Echinococcus multilocularis synaptotagmin 0.0023 0.0015 0.0007
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0066 0.0065
Onchocerca volvulus 0.0023 0.0015 0.0028
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.0045 0.1489
Leishmania major hypothetical protein, conserved 0.0023 0.0015 0.0115
Entamoeba histolytica PH domain containing protein kinase, putative 0.0156 0.0818 0.7392
Schistosoma mansoni unc-13 (munc13) 0.0175 0.0936 0.1039
Loa Loa (eye worm) hypothetical protein 0.0087 0.0401 0.0963
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Schistosoma mansoni hypothetical protein 0.0023 0.0015 0.0008
Brugia malayi Steroid receptor seven-up type 2 0.0047 0.0158 0.0352
Loa Loa (eye worm) hypothetical protein 0.017 0.0907 0.2199
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0047 0.0158 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.006 0.0474
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.0483 0.0532
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.0358 0.3173
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0066 0.0065
Echinococcus multilocularis NEDD4 E3 ubiquitin protein ligase WWP1 0.0023 0.0015 0.0007
Echinococcus granulosus metabotropic glutamate receptor 5 0.0273 0.153 0.1702
Echinococcus multilocularis RNA directed DNA polymerase 0.0543 0.3175 0.317
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.008 0.0363 0.3321
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0192 0.1042 0.1157
Schistosoma mansoni E3 ubiquitin-protein ligase nedd-4 0.0023 0.0015 0.0008
Entamoeba histolytica C2 domain containing protein 0.0023 0.0015 0.0028
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Trichomonas vaginalis synaptotagmin 1, 3, C.elegans, putative 0.0023 0.0015 0.0029
Brugia malayi Copine family protein 0.0023 0.0015 0.0017
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0095 0.0192
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis calcium-dependent lipid-binding protein, putative 0.0023 0.0015 0.0029
Echinococcus multilocularis thyroid hormone receptor alpha 0.0047 0.0158 0.015
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0088 0.019
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0058 0.0056
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.0358 0.0392
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0023 0.0015 0.0017
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0047 0.0158 0.0168
Echinococcus granulosus glutamine synthetase 0.023 0.1268 0.1409
Brugia malayi RhoGAP domain containing protein 0.0152 0.0795 0.185
Onchocerca volvulus Bile acid receptor homolog 0.0047 0.0158 0.0596
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0115 0.0982
Onchocerca volvulus 0.0032 0.0066 0.023
Trichomonas vaginalis abcb9, putative 0.0058 0.0227 0.2042
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.007 0.0556
Loa Loa (eye worm) hypothetical protein 0.0049 0.017 0.0396
Echinococcus multilocularis dna polymerase kappa 0.0041 0.012 0.0113
Schistosoma mansoni glutamine synthetase 1 2 (glutamate-amonia ligase) (gs) 0.023 0.1268 0.1409
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.012 0.022
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.007 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Trichomonas vaginalis copine, putative 0.0023 0.0015 0.0029
Echinococcus granulosus aldehyde reductase 0.0022 0.001 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Echinococcus granulosus RNA directed DNA polymerase 0.0543 0.3175 0.3542
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0115 0.0108
Brugia malayi jmjC domain containing protein 0.0097 0.0464 0.1071
Loa Loa (eye worm) hypothetical protein 0.017 0.0907 0.2199
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0058 0.0227 0.2042
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0028 0.0045 0.0162
Brugia malayi Protein kinase domain containing protein 0.0197 0.1069 0.2492
Schistosoma mansoni mctp-related 0.0023 0.0015 0.0008
Trichomonas vaginalis synaptotagmin, putative 0.0023 0.0015 0.0029
Echinococcus granulosus jumonji domain containing protein 0.0042 0.013 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.012 0.0947
Echinococcus granulosus aldo keto reductase 0.0032 0.0066 0.0065
Echinococcus granulosus synaptotagmin 0.0023 0.0015 0.0008
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0152 0.0795 0.1926
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.009 0.0627
Brugia malayi polk-prov protein 0.0031 0.006 0.0123
Loa Loa (eye worm) C2 domain-containing protein 0.0023 0.0015 0.0017
Echinococcus multilocularis aldehyde reductase 0.0022 0.001 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Schistosoma mansoni RAR-like nuclear receptor 0.0047 0.0158 0.0168
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0039
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0094 0.0442 0.0894
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.009 0.0093
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0032 0.0066 0.0517
Mycobacterium leprae GLUTAMINE SYNTHETASE GLNA1 (GLUTAMINE SYNTHASE) (Glutamate--ammonia ligase 1) (GS-I) 0.0242 0.1345 0.2707
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0158 0.0168
Brugia malayi Guanylyl cyclase protein 23 0.0025 0.0026 0.0043
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.017 0.0907 0.2199
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.0358 0.0857
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0152 0.0795 0.1926
Mycobacterium tuberculosis Conserved protein 0.004 0.0115 0.0233
Plasmodium falciparum glutamine synthetase, putative 0.0472 0.2739 1
Onchocerca volvulus 0.0129 0.0659 0.2588
Leishmania major hypothetical protein, conserved 0.0023 0.0015 0.0115
Entamoeba histolytica P-glycoprotein-2 0.0058 0.0227 0.1978
Entamoeba histolytica P-glyco protein 6, putative 0.0058 0.0227 0.1978
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0047 0.0158 0.0367
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0115 0.0211
Plasmodium falciparum glutathione reductase 0.0032 0.007 0.0216
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.008 0.0073
Echinococcus multilocularis active breakpoint cluster region 0.0023 0.0015 0.0007
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0025 0.0026 0.0018
Mycobacterium ulcerans oxidoreductase 0.0032 0.0066 0.011
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0154 0.0146
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0197 0.1072 0.25
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.007 0.0469
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0192 0.1042 0.1035
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0045 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Mycobacterium ulcerans lipase LipD 0.004 0.0115 0.0211
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0911 0.5406 0.5403
Trypanosoma brucei aldo-keto reductase, putative 0.0032 0.0066 0.0517
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0115 0.0233
Echinococcus granulosus NEDD4 E3 ubiquitin protein ligase WWP1 0.0023 0.0015 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.007 0.0469
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0032 0.0066 0.0511
Loa Loa (eye worm) hypothetical protein 0.004 0.0115 0.0263
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0032 0.0066 0.0136
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0023 0.0017
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0058 0.0227 0.2042
Loa Loa (eye worm) hypothetical protein 0.0036 0.0095 0.0213
Trichomonas vaginalis aldo-keto reductase, putative 0.0032 0.0066 0.0511
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0175 0.0936 0.1039
Onchocerca volvulus 0.0024 0.0019 0.0046
Schistosoma mansoni hypothetical protein 0.0023 0.0015 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0047 0.0158 0.0352
Loa Loa (eye worm) hypothetical protein 0.0067 0.0282 0.0671
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0025 0.002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0045
Schistosoma mansoni multidrug resistance protein 0.0058 0.0227 0.0246
Brugia malayi calpain 5 0.0023 0.0015 0.0017
Schistosoma mansoni hypothetical protein 0.0035 0.0084 0.0085
Entamoeba histolytica C2 domain containing protein 0.0023 0.0015 0.0028
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0192 0.1042 0.1035
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Echinococcus granulosus nmda type glutamate receptor 0.0025 0.0026 0.002
Schistosoma mansoni hypothetical protein 0.0044 0.0143 0.0152
Plasmodium vivax hypothetical protein, conserved 0.004 0.0115 0.038
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0035 0.0088 0.0321
Mycobacterium leprae PROBABLE GLUTAMINE SYNTHETASE GLNA2 (GLUTAMINE SYNTHASE) (GS-II) 0.0472 0.2739 0.5535
Trichomonas vaginalis AGC family protein kinase 0.0192 0.1042 0.975
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0039
Echinococcus multilocularis calpain 5 0.0023 0.0015 0.0007
Brugia malayi Protein kinase c protein 2 0.0723 0.4266 1
Echinococcus granulosus protein piccolo 0.0023 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0543 0.3175 0.7746
Loa Loa (eye worm) Nedd4-PD 0.0023 0.0015 0.0017
Mycobacterium ulcerans hypothetical protein 0.0049 0.017 0.0321
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0158 0.0168
Schistosoma mansoni cpg binding protein 0.0059 0.0231 0.025
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0095 0.0169
Onchocerca volvulus 0.0023 0.0015 0.0028
Brugia malayi hypothetical protein 0.0025 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0047 0.0158 0.0367
Schistosoma mansoni hypothetical protein 0.0023 0.0015 0.0008
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.017 0.0321
Entamoeba histolytica hypothetical protein 0.0023 0.0015 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.017 0.0321
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0015 0.0025
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0156 0.0823 0.0912
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0158 0.0352
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Trypanosoma brucei cAMP binding protein, putative 0.0023 0.0015 0.0115
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0213 0.117 0.2353
Schistosoma mansoni metabotropic glutamate receptor 0.0187 0.101 0.1121
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0181 0.0424
Loa Loa (eye worm) hypothetical protein 0.004 0.0115 0.0263
Echinococcus granulosus serine:threonine protein kinase N2 0.0192 0.1042 0.1157
Entamoeba histolytica acyl-CoA synthetase, putative 0.0054 0.0203 0.1757
Onchocerca volvulus Protein ultraspiracle homolog 0.0047 0.0158 0.0596
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0058 0.0223 0.0242
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0058 0.0227 0.2042
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0061 0.0247 0.024
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.009 0.0083
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0047 0.0158 0.0168
Leishmania major trypanothione reductase 0.0094 0.0442 0.3485
Brugia malayi Doublecortin family protein 0.0044 0.0143 0.0319
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0115 0.0253
Schistosoma mansoni unc-13 (munc13) 0.0175 0.0936 0.1039
Trichomonas vaginalis annexin VII, putative 0.0023 0.0015 0.0029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.012 0.0864
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.0023 0.0015 0.0008
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.012 0.0947
Brugia malayi Ras association domain family 1 isoform A 0.0152 0.0795 0.185
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.008 0.0081
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0058 0.0227 0.2042
Leishmania major glutamine synthetase, putative 0.023 0.1268 1
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0058 0.0056
Brugia malayi Metabotropic glutamate receptor precursor. 0.0222 0.1224 0.2857
Trypanosoma cruzi glutamine synthetase, putative 0.023 0.1268 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0045 0.0123
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0023 0.0015 0.0017
Schistosoma mansoni coup transcription factor 0.0047 0.0158 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0158 0.0352
Echinococcus multilocularis aldo keto reductase 0.0032 0.0066 0.0058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.007 0.0469
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0058 0.0227 0.0538
Onchocerca volvulus Poor gastrulation protein homolog 0.0035 0.0088 0.0321
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0047 0.0158 0.0367
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0117 0.0582 0.0575
Trichomonas vaginalis AGC family protein kinase 0.0197 0.1069 1
Trichomonas vaginalis abcb9, putative 0.0058 0.0227 0.2042
Echinococcus multilocularis thioredoxin glutathione reductase 0.0094 0.0445 0.0438
Echinococcus multilocularis glutamine synthetase 0.023 0.1268 0.1261
Mycobacterium tuberculosis Probable oxidoreductase 0.0032 0.0066 0.0133
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0115 0.0211
Schistosoma mansoni jumonji domain containing protein 0.0136 0.07 0.0774
Schistosoma mansoni ap endonuclease 0.0023 0.0011 0.0004
Echinococcus granulosus NDR protein kinase 0.0192 0.1042 0.1157
Schistosoma mansoni single-minded 0.0048 0.0164 0.0175
Schistosoma mansoni survival motor neuron protein 0.0053 0.0197 0.0212
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0058 0.0227 0.2042
Schistosoma mansoni serine/threonine protein kinase 0.0192 0.1042 0.1157
Echinococcus multilocularis extended synaptotagmin 2 0.0023 0.0015 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Schistosoma mansoni synaptotagmin 0.0023 0.0015 0.0008
Trypanosoma brucei predicted C2 domain protein 0.0023 0.0015 0.0115
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.007 0.0148
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.0483 0.0476
Brugia malayi beta-lactamase family protein 0.004 0.0115 0.0253
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.009 0.0627
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Brugia malayi jmjC domain containing protein 0.0025 0.0025 0.0042
Trichomonas vaginalis synaptotagmin, putative 0.0023 0.0015 0.0029
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0095 0.3809
Echinococcus granulosus aldo keto reductase 0.0032 0.0066 0.0065
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0213 0.117 0.2368
Brugia malayi hypothetical protein 0.043 0.2483 0.5813
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.017 0.1338
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Onchocerca volvulus Multiple C2 domain and transmembrane region protein homolog 0.0023 0.0015 0.0028
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0047 0.0158 0.015
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0058 0.0227 1
Schistosoma mansoni hypothetical protein 0.0423 0.2442 0.2723
Brugia malayi Protein kinase domain containing protein 0.0192 0.1042 0.243
Loa Loa (eye worm) hypothetical protein 0.0044 0.0143 0.0332
Schistosoma mansoni glut4 vesicle protein-related 0.0023 0.0015 0.0008
Plasmodium vivax thioredoxin reductase, putative 0.0094 0.0442 0.1578
Leishmania major hypothetical protein, conserved 0.0025 0.0025 0.0201
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0047 0.0158 0.0367
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0058 0.0227 0.022
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0039
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0143 0.0136
Trichomonas vaginalis synaptotagmin 1, 3, C.elegans, putative 0.0023 0.0015 0.0029
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0047 0.0158 0.0168
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0045 0.0123
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.009 0.038
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0571 0.3344 0.816
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0286 0.1609 0.376
Loa Loa (eye worm) hypothetical protein 0.0156 0.0822 0.1991
Loa Loa (eye worm) hypothetical protein 0.0058 0.0227 0.0538
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.017 0.0343
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0058 0.0227 0.2042
Echinococcus granulosus atrial natriuretic peptide receptor 0.0025 0.0026 0.002
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0058 0.0227 0.2042
Schistosoma mansoni hypothetical protein 0.0035 0.0088 0.009
Echinococcus granulosus multiple C2 and transmembrane domain containing protein 0.0023 0.0015 0.0008
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Schistosoma mansoni hypothetical protein 0.0084 0.0382 0.0419
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0066 0.0065
Mycobacterium ulcerans hypothetical protein 0.0242 0.1345 0.2705
Trypanosoma brucei C2 domain containing protein, putative 0.0023 0.0015 0.0115
Trichomonas vaginalis glutamine synthetase, putative 0.0122 0.0613 0.5692
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0025 0.0018
Loa Loa (eye worm) glutamate receptor 0.0222 0.1224 0.2975
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Echinococcus granulosus expressed conserved protein 0.019 0.1028 0.1142
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.007 0.012
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0011 0.0004
Echinococcus granulosus peregrin 0.003 0.0058 0.0056
Brugia malayi hypoxia-induced factor 1 0.0148 0.0772 0.1795
Schistosoma mansoni hypothetical protein 0.0084 0.0382 0.0419
Trypanosoma brucei Coiled-coil and C2 domain-containing protein 0.0023 0.0015 0.0115
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0024 0.0018
Trichomonas vaginalis ABC transporter, putative 0.0058 0.0227 0.2042
Loa Loa (eye worm) hypothetical protein 0.0047 0.0158 0.0367
Trypanosoma brucei predicted C2 domain protein 0.0023 0.0015 0.0115
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Schistosoma mansoni rho gtpase activating protein 0.0023 0.0015 0.0008
Echinococcus multilocularis serine:threonine protein kinase 38 0.0192 0.1042 0.1035
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0028 0.0045 0.5693
Trichomonas vaginalis AGC family protein kinase 0.0197 0.1069 1
Loa Loa (eye worm) AGC/NDR protein kinase 0.0192 0.1042 0.253
Plasmodium falciparum thioredoxin reductase 0.0032 0.007 0.0216
Echinococcus granulosus receptor type guanylyl cyclase 0.0025 0.0026 0.002
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.012 0.0947
Entamoeba histolytica aldose reductase, putative 0.0032 0.0066 0.0495
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0192 0.1042 0.1157
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.004 0.0115 0.0263
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0023 0.0015 0.0017
Schistosoma mansoni unc-13 (munc13) 0.0023 0.0015 0.0008
Brugia malayi diacylglycerol kinase 0.0152 0.0795 0.185
Entamoeba histolytica C2 domain containing protein 0.0023 0.0015 0.0028
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.009 0.016
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0032 0.0066 0.0136
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Loa Loa (eye worm) C2 domain-containing protein 0.0023 0.0015 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.007 0.0469
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0117 0.0582 0.0643
Trichomonas vaginalis copine, putative 0.0023 0.0015 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0158 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Entamoeba histolytica hypothetical protein 0.0117 0.0582 0.523
Trichomonas vaginalis AGC family protein kinase 0.0192 0.1042 0.975
Echinococcus multilocularis 0.0023 0.0015 0.0007
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.017 0.0321
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0152 0.0795 0.1926
Entamoeba histolytica C2 domain protein, putative 0.0023 0.0015 0.0028
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0088 0.0156
Schistosoma mansoni serine/threonine protein kinase 0.0911 0.5406 0.6038
Echinococcus granulosus multidrug resistance protein 1 0.0058 0.0227 0.0246
Schistosoma mansoni glutamine synthetase bacteria 0.0364 0.2084 0.2323
Loa Loa (eye worm) hypothetical protein 0.0152 0.0795 0.1926
Echinococcus multilocularis microtubule associated protein 2 0.1494 0.895 0.8949
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0188 0.1014 0.9484
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0115 0.0982
Treponema pallidum NADH oxidase 0.0032 0.007 1
Loa Loa (eye worm) matrixin family protein 0.0038 0.0101 0.0229
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0058 0.0227 0.2042
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.012 0.0947
Echinococcus multilocularis RUN 0.0044 0.0143 0.0136
Echinococcus multilocularis neural cell expressed, developmentally 0.0023 0.0015 0.0007
Brugia malayi Niemann-Pick C1 protein precursor 0.0202 0.1103 0.2573
Entamoeba histolytica C2 domain containing protein 0.0023 0.0015 0.0028
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0401 0.3686
Loa Loa (eye worm) inositol-1 0.0036 0.009 0.0202
Echinococcus granulosus glutamate receptor 2 0.0025 0.0026 0.002
Loa Loa (eye worm) Gln-2 protein 0.023 0.1268 0.3082
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0058 0.0227 0.2042
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0058 0.005
Trichomonas vaginalis copine, putative 0.0023 0.0015 0.0029
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0047 0.0158 0.015
Toxoplasma gondii AGC kinase 0.0192 0.1042 0.3779
Echinococcus multilocularis Polycystic kidney disease protein 0.0044 0.0143 0.0136
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.0358 0.2822
Echinococcus granulosus copine 9 0.0023 0.0015 0.0008
Echinococcus multilocularis synaptotagmin 15 0.0023 0.0015 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0015 0.0011
Echinococcus multilocularis Protein lozenge 0.0054 0.0201 0.0193
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.007 0.0469
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0018 0.0025
Entamoeba histolytica diacylglycerol kinase, putative 0.0152 0.0795 0.718
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0034 0.008 0.0081
Schistosoma mansoni aldo-keto reductase 0.0032 0.0066 0.0065
Trypanosoma cruzi extracellular receptor, putative 0.0025 0.0026 0.0114
Schistosoma mansoni diacylglycerol kinase theta 0.0152 0.0795 0.0881
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0058 0.0227 0.2042
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0026 0.0045
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0032 0.0066 0.0058
Echinococcus granulosus thioredoxin glutathione reductase 0.0094 0.0445 0.0489
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0198 0.1078 0.1197
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0025 0.002
Schistosoma mansoni vav2 0.0156 0.0822 0.091
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0115 0.012
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0023 0.0015 0.0025
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0058 0.0227 0.2042
Entamoeba histolytica protein kinase, putative 0.0192 0.1042 0.9443
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.007 0.0558
Trypanosoma cruzi C2 domain/Ankyrin repeats (3 copies), putative 0.0023 0.0015 0.0025
Entamoeba histolytica P-glycoprotein 5, putative 0.0058 0.0227 0.1978
Echinococcus granulosus Diacylglycerol kinase theta 0.0152 0.0795 0.0881
Echinococcus granulosus Protein kinase C brain isozyme 0.0911 0.5406 0.6038
Brugia malayi PHD-finger family protein 0.003 0.0058 0.0118
Echinococcus multilocularis aldo keto reductase 0.0032 0.0066 0.0058
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0158 0.0168
Plasmodium falciparum thioredoxin reductase 0.0094 0.0442 0.1578
Onchocerca volvulus 0.004 0.0115 0.0428
Trypanosoma brucei predicted C2 domain protein 0.0023 0.0015 0.0115
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0197 0.1069 1
Onchocerca volvulus 0.0059 0.0231 0.0887
Loa Loa (eye worm) hypothetical protein 0.0152 0.0795 0.1926
Trypanosoma brucei C2 domain containing protein, putative 0.0023 0.0015 0.0115
Echinococcus granulosus synaptotagmin protein 4 0.0023 0.0015 0.0008
Brugia malayi Copine VIII 0.0023 0.0015 0.0017
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0058 0.0227 0.2042
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0011 0.0009
Schistosoma mansoni tyrosine kinase 0.0025 0.0026 0.002
Leishmania major p-glycoprotein 0.0058 0.0227 0.1793
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0095 0.0305
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0543 0.3175 0.317
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0028 0.0041 0.0082
Leishmania major hypothetical protein, conserved 0.0023 0.0015 0.0115
Loa Loa (eye worm) hypothetical protein 0.0152 0.0795 0.1926
Toxoplasma gondii hypothetical protein 0.0023 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0152 0.0795 0.1926
Schistosoma mansoni glutamate receptor NMDA 0.0034 0.008 0.0081
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.012 0.022
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0156 0.0824 0.0913
Echinococcus multilocularis serine:threonine protein kinase N2 0.0192 0.1042 0.1035
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0115 0.0826
Loa Loa (eye worm) hypothetical protein 0.0436 0.2524 0.6155
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Trichomonas vaginalis synaptotagmin, putative 0.0023 0.0015 0.0029
Toxoplasma gondii thioredoxin reductase 0.0094 0.0442 0.1578
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0023 0.0013 0.0286
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0047 0.0158 0.0352
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0115 0.0233
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.017 0.0343
Echinococcus multilocularis NADH dehydrogenase (ubiquinone) flavoprotein 1 0.008 0.0363 0.0355
Schistosoma mansoni transcription factor LCR-F1 0.0117 0.0582 0.0643
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.0483 0.1118
Loa Loa (eye worm) hypothetical protein 0.0036 0.0095 0.0213
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0041 0.0079
Schistosoma mansoni multidrug resistance protein 0.0058 0.0227 0.0246
Wolbachia endosymbiont of Brugia malayi glutamine synthetase 0.0364 0.2084 1
Schistosoma mansoni synaptotagmin 0.0023 0.0015 0.0008
Echinococcus multilocularis dnaJ subfamily B 0.0423 0.2442 0.2437
Brugia malayi C2 domain containing protein 0.0023 0.0015 0.0017
Schistosoma mansoni copine 0.0023 0.0015 0.0008
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0032 0.0066 0.0065
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0047 0.0158 0.0168
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0514 0.2995 0.7306
Echinococcus multilocularis aldo keto reductase 0.0032 0.0066 0.0058
Onchocerca volvulus 0.0032 0.0066 0.023
Schistosoma mansoni hypothetical protein 0.0084 0.0382 0.0419
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0152 0.0795 0.0788
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0028 0.0046 0.0038
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0023 0.0015 0.0008
Echinococcus granulosus synaptotagmin 0.0023 0.0015 0.0008
Brugia malayi Variant SH3 domain containing protein 0.0152 0.0795 0.185
Entamoeba histolytica calcium-binding protein, putative 0.0023 0.0015 0.0028
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0025 0.0111
Echinococcus granulosus Immunoglobulin E set 0.0023 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0047 0.0158 0.0367
Brugia malayi hypothetical protein 0.0044 0.0143 0.0319
Toxoplasma gondii C2 domain-containing protein 0.0023 0.0015 0.0011
Onchocerca volvulus 0.0044 0.0143 0.0539
Echinococcus granulosus copine 9 0.0023 0.0015 0.0008
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0015 0.0028
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0025 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0015 0.0029
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0024 0.0038
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0023 0.0015 0.0115
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0088 0.0081
Onchocerca volvulus Matrix metalloproteinase homolog 0.0038 0.0101 0.0373
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0158 0.015
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0058 0.0227 0.0246
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0047 0.0158 0.015
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0045
Echinococcus multilocularis expressed conserved protein 0.019 0.1028 0.1022
Brugia malayi nuclear receptor NHR-88 0.0047 0.0158 0.0352
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0358 0.2756
Schistosoma mansoni protein kinase 0.0025 0.0026 0.002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0254 0.1418 0.287
Echinococcus multilocularis protein patched 0.0087 0.0401 0.0394
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0158 0.0352
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0058 0.0227 0.2042
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0115 0.0263
Echinococcus multilocularis lysine specific demethylase 5A 0.0094 0.0443 0.0436
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.012 0.0947
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.0358 0.0351
Echinococcus multilocularis Niemann Pick C1 protein 0.0202 0.1103 0.1096
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0028 0.0046 0.0043
Mycobacterium ulcerans hypothetical protein 0.0122 0.0613 0.1221
Leishmania major aldo-keto reductase-like protein 0.0032 0.0066 0.0517
Loa Loa (eye worm) hypothetical protein 0.0058 0.0227 0.0538
Schistosoma mansoni synaptotagmin 12 0.0023 0.0015 0.0008
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.007 0.2675
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0143 0.0483
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.009 0.0745
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0237 0.1315 0.2661
Trypanosoma cruzi glutamine synthetase, putative 0.023 0.1268 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0024 0.0039
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0015 0.0115
Echinococcus multilocularis receptor type guanylyl cyclase 0.0025 0.0026 0.0018
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.1461 0.1626
Loa Loa (eye worm) hypothetical protein 0.0106 0.052 0.1253
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.007 0.0556
Echinococcus granulosus multidrug resistance protein 1 0.0058 0.0227 0.0246
Trichomonas vaginalis AGC family protein kinase 0.0192 0.1042 0.975
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0017
Echinococcus granulosus Niemann Pick C1 protein 0.0202 0.1103 0.1225

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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