Detailed information for compound 591760

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 436.977 | Formula: C25H29ClN4O
  • H donors: 2 H acceptors: 2 LogP: 4.2 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cccc2c1C(C)(CCCCN1CCC(CC1)c1c[nH]c3c1ccnc3)C(=O)N2
  • InChi: 1S/C25H29ClN4O/c1-25(23-20(26)5-4-6-21(23)29-24(25)31)10-2-3-12-30-13-8-17(9-14-30)19-15-28-22-16-27-11-7-18(19)22/h4-7,11,15-17,28H,2-3,8-10,12-14H2,1H3,(H,29,31)
  • InChiKey: FANVJTHERLEFBY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Mycobacterium tuberculosis Probable reductase 0.0202 0.0446 0.2047
Trypanosoma cruzi C-8 sterol isomerase, putative 0.4248 1 1
Schistosoma mansoni carbonic anhydrase-related 0.0058 0.0106 0.0173
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0057 0.0102 0.0168
Mycobacterium ulcerans short chain dehydrogenase 0.0559 0.1289 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0114 0.1987
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0027 0.0041
Echinococcus multilocularis serotonin transporter 0.1012 0.2357 0.3924
Plasmodium falciparum T-complex protein 1 subunit beta 0.0025 0.0027 0.0153
Schistosoma mansoni zinc finger protein 0.0015 0.0003 0.0002
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0015 0.0003 0.0009
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0062 0.0114 0.0688
Loa Loa (eye worm) hypothetical protein 0.0058 0.0106 0.0106
Echinococcus granulosus neuropeptide s receptor 0.1205 0.2815 0.4686
Echinococcus multilocularis polycomb protein SCMH1 0.0032 0.0044 0.0071
Mycobacterium ulcerans aldehyde dehydrogenase 0.02 0.044 0.3404
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0101 0.0206 0.0206
Loa Loa (eye worm) isocitrate dehydrogenase 0.006 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus multilocularis sex peptide receptor 0.0654 0.1513 0.2518
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0042 0.0067
Onchocerca volvulus 0.0654 0.1513 0.252
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0061 0.0272
Plasmodium vivax thioredoxin reductase, putative 0.0089 0.0178 0.1084
Plasmodium vivax hypothetical protein, conserved 0.0311 0.0703 0.4324
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0311 0.0703 0.0701
Echinococcus multilocularis heat shock protein 90 0.0018 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0146 0.0313 0.0313
Schistosoma mansoni patched 1 0.0023 0.0023 0.0034
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0049 0.0085 0.27
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0133
Brugia malayi Isocitrate dehydrogenase 0.006 0.0109 0.0107
Echinococcus multilocularis musashi 0.0053 0.0094 0.0153
Entamoeba histolytica zinc finger protein, putative 0.0021 0.0018 0.0357
Loa Loa (eye worm) nuclear factor I 0.0018 0.0011 0.0011
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0311 0.0703 0.0703
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0057 0.0102 0.1785
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0003 0.0002
Brugia malayi sulfakinin receptor protein 0.0654 0.1513 0.1512
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0288 0.0477
Echinococcus granulosus tumor protein p63 0.0205 0.0452 0.0751
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0016 0.0006 0.0019
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0015 0.0004 0.0048
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Onchocerca volvulus 0.0311 0.0703 0.1171
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0015 0.0004 0.0004
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0017 0.0008 0.004
Schistosoma mansoni importin beta-1 0.0019 0.0014 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Trypanosoma brucei carbonic anhydrase-like protein 0.0124 0.0261 0.0261
Schistosoma mansoni pyruvate kinase 0.0023 0.0022 0.0033
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0038 0.0057 0.0339
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0026 0.0031 0.0048
Brugia malayi 6-phosphofructokinase 0.0063 0.0117 0.0115
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0015 0.0004 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0042 0.0067
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0654 0.1513 0.1512
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0198 0.0435 0.0723
Brugia malayi G protein-coupled receptor 0.0654 0.1513 0.1512
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0031 0.0041 0.0305
Schistosoma mansoni hypothetical protein 0.0118 0.0247 0.0407
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0025 0.0027 0.0042
Onchocerca volvulus 0.0654 0.1513 0.252
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.0289
Schistosoma mansoni Smad4 0.0015 0.0003 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0654 0.1513 0.2518
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0042 0.004
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0017 0.0008 0.0688
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0037 0.0054 0.0054
Echinococcus granulosus allatostatin A receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Schistosoma mansoni biogenic amine receptor 0.0654 0.1513 0.2518
Brugia malayi neuropeptide F receptor 0.0654 0.1513 0.1512
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0198 0.0435 0.0723
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0021 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0049 0.0085 0.0512
Plasmodium falciparum importin beta, putative 0.0019 0.0014 0.0075
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0654 0.1513 0.1513
Loa Loa (eye worm) 6-phosphofructokinase 0.0063 0.0117 0.0117
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0016 0.0006 0.0082
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0021 0.0019 0.0308
Echinococcus multilocularis rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Entamoeba histolytica hypothetical protein 0.0118 0.0247 0.5517
Onchocerca volvulus 0.007 0.0133 0.0221
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0026 0.0031 0.0048
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0014 0.0002 0.0044
Schistosoma mansoni biogenic amine (5HT) receptor 0.0971 0.2261 0.3763
Giardia lamblia Histone acetyltransferase GCN5 0.0056 0.0101 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0146 0.0313 0.2423
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0061 0.0098
Brugia malayi Carboxylesterase family protein 0.0412 0.0942 0.094
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0313 0.5536
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0058 0.0106 0.0104
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0055
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0035 0.0052 0.0084
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0025 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Schistosoma mansoni hypothetical protein 0.0022 0.0021 0.0031
Entamoeba histolytica hypothetical protein 0.0021 0.0018 0.0357
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0654 0.1513 0.2518
Brugia malayi hypothetical protein 0.0467 0.1072 0.107
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0042 0.0067
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0029 0.0029
Onchocerca volvulus 0.0311 0.0703 0.1171
Loa Loa (eye worm) pyruvate kinase-PB 0.0016 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.0595
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Brugia malayi hypothetical protein 0.0057 0.0102 0.01
Brugia malayi Serotonin receptor 0.0654 0.1513 0.1512
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0042 0.0067
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0117 0.2049
Brugia malayi hypothetical protein 0.0312 0.0706 0.0704
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0019 0.0013 0.0013
Echinococcus multilocularis geminin 0.0844 0.1962 0.3265
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0075 0.0146 0.0241
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0055 0.0097 0.0158
Brugia malayi Carboxylesterase family protein 0.007 0.0133 0.0131
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0042 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0042 0.0042
Echinococcus granulosus transient receptor potential gamma protein 0.0091 0.0182 0.0301
Schistosoma mansoni carbonic anhydrase 0.0058 0.0106 0.0173
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0054 0.0095 0.2098
Toxoplasma gondii hypothetical protein 0.0017 0.0008 0.004
Plasmodium vivax endoplasmin, putative 0.0018 0.001 0.005
Echinococcus granulosus SAM and MBT domain containing protein 0.0032 0.0044 0.0071
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Treponema pallidum NADH oxidase 0.0031 0.0041 0.0167
Brugia malayi vesicular acetylcholine transporter unc-17 0.2556 0.6005 0.6004
Loa Loa (eye worm) hypothetical protein 0.009 0.018 0.018
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.0022 0.002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0061 0.0362
Schistosoma mansoni transient receptor potential channel 4 0.0091 0.0182 0.03
Loa Loa (eye worm) hypothetical protein 0.0467 0.1072 0.1072
Loa Loa (eye worm) carboxylesterase 0.0412 0.0942 0.0942
Echinococcus granulosus sodium and chloride dependent glycine 0.0311 0.0703 0.1169
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0031 0.0041 0.0041
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0209 0.0462 0.0767
Brugia malayi MH2 domain containing protein 0.0015 0.0003 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0049 0.0078
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0313 0.5536
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0038 0.0057 0.0092
Onchocerca volvulus Glucosylceramidase homolog 0.012 0.0251 0.0417
Entamoeba histolytica phosphofructokinase, putative 0.0063 0.0117 0.2595
Loa Loa (eye worm) hypothetical protein 0.0038 0.0057 0.0057
Echinococcus multilocularis expressed conserved protein 0.005 0.0087 0.0143
Schistosoma mansoni heat shock protein 0.0018 0.001 0.0013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0288 0.0478
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0063 0.0117 0.0532
Brugia malayi RE15519p 0.0654 0.1513 0.1512
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0004
Echinococcus granulosus 7TM GPCR rhodopsin 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Echinococcus granulosus microtubule associated protein 2 0.0445 0.1018 0.1693
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0038 0.0057 0.0057
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0063 0.0117 0.2319
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0042 0.004
Echinococcus granulosus 7tm_1 domain containing protein 0.0654 0.1513 0.2518
Schistosoma mansoni neuropeptide receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0007 0.0007
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.013 0.0275 0.5491
Trichomonas vaginalis ran, putative 0.0014 0.0002 0.0008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0032 0.068
Loa Loa (eye worm) hypothetical protein 0.0052 0.0091 0.0091
Echinococcus granulosus neuropeptide receptor 0.0654 0.1513 0.2518
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0025 0.0027 0.0027
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.0022 0.0037
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.0288 0.0286
Onchocerca volvulus 0.0053 0.0094 0.0156
Trichomonas vaginalis importin beta-1, putative 0.0016 0.0005 0.0069
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0032 0.0045 0.0199
Echinococcus multilocularis serotonin receptor 0.0971 0.2261 0.3764
Mycobacterium tuberculosis Conserved hypothetical protein 0.0112 0.0233 0.1067
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0057 0.0102 0.0168
Trypanosoma cruzi heat shock protein 85, putative 0.0018 0.001 0.001
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0037 0.0055 0.0053
Loa Loa (eye worm) mbt repeat family protein 0.0032 0.0044 0.0044
Mycobacterium ulcerans aldehyde dehydrogenase 0.02 0.044 0.3404
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0057 0.0102 0.0168
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0202 0.0446 0.2047
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0031
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0117 0.2049
Entamoeba histolytica pyruvate kinase, putative 0.0016 0.0006 0.0083
Echinococcus multilocularis sodium and chloride dependent glycine 0.0311 0.0703 0.1169
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0057 0.0102 0.0168
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0021 0.0019 0.0104
Mycobacterium leprae Probable polyketide synthase Pks1 0.0016 0.0006 0.0082
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0038 0.0057 0.0057
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.003 0.0039 0.0039
Brugia malayi larval opioid receptor 0.0654 0.1513 0.1512
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.007 0.0133 0.0604
Echinococcus granulosus transcription factor eb 0.0061 0.0112 0.0184
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.02 0.044 0.073
Entamoeba histolytica hypothetical protein 0.0118 0.0247 0.5517
Echinococcus granulosus carbonic anhydrase 0.0058 0.0106 0.0174
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0026 0.0031 0.0048
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0028 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0134 0.0286 0.0286
Echinococcus multilocularis g-protein coupled receptor 0.0654 0.1513 0.2518
Brugia malayi hypothetical protein 0.0016 0.0007 0.0005
Echinococcus multilocularis G-protein coupled receptor, putative 0.0654 0.1513 0.2518
Schistosoma mansoni acetylcholinesterase 0.007 0.0133 0.0218
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.006 0.0109 0.0179
Onchocerca volvulus 0.0053 0.0094 0.0156
Schistosoma mansoni tankyrase 0.0021 0.0018 0.0026
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0003 0.0001
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0021 0.0019 0.0019
Echinococcus multilocularis neuropeptide Y receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) pyruvate kinase 0.0023 0.0022 0.0022
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0031 0.0031
Echinococcus granulosus family S9 non peptidase ue S09 family 0.007 0.0133 0.0219
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0198 0.0435 0.0723
Echinococcus granulosus ubiquitin specific protease 41 0.0026 0.0031 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0022
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0202 0.0446 0.2047
Echinococcus multilocularis sterol regulatory element binding protein 0.0023 0.0023 0.0035
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0311 0.0703 0.1169
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0118 0.0247 0.0408
Echinococcus multilocularis inositol monophosphatase 1 0.0145 0.0311 0.0515
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0313 0.0519
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0061 0.1912
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0654 0.1513 0.2518
Schistosoma mansoni transient receptor potential channel 0.0063 0.0117 0.0192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0654 0.1513 0.2518
Echinococcus granulosus histone acetyltransferase KAT2B 0.0062 0.0114 0.0186
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1253 0.2927 0.4872
Brugia malayi follicle stimulating hormone receptor 0.0654 0.1513 0.1512
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.004 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0061 0.0112 0.011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Echinococcus multilocularis aminopeptidase N 0.0127 0.0269 0.0445
Mycobacterium ulcerans polyketide synthase 0.0015 0.0003 0.0015
Echinococcus multilocularis para nitrobenzyl esterase 0.007 0.0133 0.0219
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0654 0.1513 0.2518
Plasmodium vivax 6-phosphofructokinase, putative 0.0017 0.0008 0.004
Brugia malayi Serotonin receptor 0.0654 0.1513 0.1512
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0701 0.1624 1
Mycobacterium leprae POSSIBLE MONOPHOSPHATASE CYSQ 0.0015 0.0004 0.0052
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0038 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Brugia malayi RNA binding protein 0.0088 0.0175 0.0173
Schistosoma mansoni smad1 5 8 and 0.0033 0.0046 0.0074
Echinococcus multilocularis pyruvate kinase 0.0018 0.0011 0.0015
Onchocerca volvulus 0.0032 0.0044 0.0073
Trypanosoma brucei Heat shock protein 83, putative 0.0018 0.001 0.001
Echinococcus multilocularis transient receptor potential ion channel A 0.0078 0.0153 0.0252
Echinococcus multilocularis carboxylesterase 5A 0.0412 0.0942 0.1567
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0311 0.0703 0.1168
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.0595
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.0062
Echinococcus multilocularis BC026374 protein (S09 family) 0.007 0.0133 0.0219
Leishmania major myo-inositol-1 phosphatase, putative 0.0015 0.0004 0.0004
Giardia lamblia Hypothetical protein 0.0015 0.0004 0.0258
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0053
Echinococcus multilocularis somatostatin receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0311 0.0703 0.0703
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0031 0.0041 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Loa Loa (eye worm) histone methyltransferase 0.004 0.0062 0.0062
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0311 0.0703 0.4324
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0035 0.0595
Loa Loa (eye worm) transcription factor SMAD2 0.0486 0.1116 0.1116
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0015 0.0003 0.0009
Echinococcus multilocularis tankyrase 0.0021 0.0018 0.0027
Schistosoma mansoni hypothetical protein 0.0654 0.1513 0.2518
Echinococcus multilocularis snurportin 1 0.0207 0.0458 0.076
Leishmania major T-complex protein 1, beta subunit, putative 0.0025 0.0027 0.0027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0654 0.1513 0.2518
Plasmodium falciparum thioredoxin reductase 0.0031 0.0041 0.0239
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0213 0.0472 0.0472
Echinococcus granulosus somatostatin receptor 0.0654 0.1513 0.2518
Plasmodium falciparum zinc finger protein, putative 0.0015 0.0003 0.0006
Schistosoma mansoni hypothetical protein 0.0654 0.1513 0.2518
Brugia malayi heat shock protein 90 0.0018 0.001 0.0008
Mycobacterium ulcerans beta-lactamase 0.0146 0.0313 0.2423
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0058 0.0106 0.0104
Echinococcus granulosus g protein coupled receptor 0.0654 0.1513 0.2518
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0122 0.0257 0.0255
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0182 0.0399 0.0399
Schistosoma mansoni lamin 0.0053 0.0094 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.0289
Echinococcus multilocularis neuropeptide Y receptor 0.0654 0.1513 0.2518
Leishmania major pyruvate kinase 0.0023 0.0022 0.0022
Trypanosoma cruzi Aminopeptidase M1, putative 0.0057 0.0102 0.0102
Leishmania major mitochondrial DNA polymerase beta 0.0213 0.0472 0.0472
Onchocerca volvulus 0.0126 0.0266 0.0443
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0021 0.0019 0.0017
Plasmodium vivax 6-phosphofructokinase, putative 0.0017 0.0008 0.004
Schistosoma mansoni amine GPCR 0.0654 0.1513 0.2518
Onchocerca volvulus 0.0467 0.1072 0.1785
Mycobacterium tuberculosis Probable esterase LipL 0.0146 0.0313 0.1436
Loa Loa (eye worm) Smad1 0.0033 0.0046 0.0046
Brugia malayi glutaminase DH11.1 0.0154 0.0332 0.033
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0004
Onchocerca volvulus 0.0146 0.0313 0.0522
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0029 0.0045
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0038 0.0057 0.0057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.006 0.0109 0.066
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Brugia malayi nuclear receptor RXR 0.0015 0.0003 0.0001
Onchocerca volvulus 0.0311 0.0703 0.1171
Onchocerca volvulus 0.0654 0.1513 0.252
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0042 0.004
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0133
Schistosoma mansoni myelin transcription factor 1 myt1 0.0037 0.0055 0.0088
Loa Loa (eye worm) pyruvate kinase 0.0023 0.0022 0.0022
Entamoeba histolytica phosphofructokinase, putative 0.0063 0.0117 0.2595
Loa Loa (eye worm) hypothetical protein 0.0122 0.0257 0.0257
Echinococcus granulosus aminopeptidase N 0.0127 0.0269 0.0445
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0032 0.0044 0.0073
Schistosoma mansoni sex comb on midleg homolog 0.0032 0.0044 0.007
Brugia malayi hypothetical protein 0.1031 0.2402 0.24
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0057 0.0102 0.0168
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0032 0.0045 0.0199
Onchocerca volvulus 0.0015 0.0003 0.0005
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0654 0.1513 0.1513
Leishmania major GTP-binding protein, putative 0.0014 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0042 0.004
Schistosoma mansoni opsin-like receptor 0.0654 0.1513 0.2518
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0145 0.0311 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0145 0.0311 0.0311
Echinococcus granulosus poly ADP ribose polymerase 1 0.0202 0.0445 0.0739
Schistosoma mansoni hypothetical protein 0.1515 0.3545 0.5903
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0035 0.0052 0.0052
Echinococcus multilocularis inositol monophosphatase 0.0015 0.0004 0.0004
Brugia malayi Carboxylesterase family protein 0.0412 0.0942 0.094
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0075 0.0146 0.0241
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0049 0.0085 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.0289
Loa Loa (eye worm) TATA binding protein associated factor 0.0038 0.0057 0.0057
Mycobacterium ulcerans hypothetical protein 0.0146 0.0313 0.2423
Mycobacterium tuberculosis Carboxylesterase LipT 0.007 0.0133 0.0604
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.006 0.0109 0.0109
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0202 0.0445 0.0739
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0062 0.0114 0.0688
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0311 0.0703 0.0701
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0017 0.0008 0.0139
Echinococcus multilocularis rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Plasmodium vivax SET domain protein, putative 0.0034 0.0049 0.029
Schistosoma mansoni neuropeptide f receptor 76f 0.0654 0.1513 0.2518
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0017 0.0008 0.004
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0031 0.0041 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0029 0.0124
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0062 0.0101
Loa Loa (eye worm) hypothetical protein 0.0146 0.0313 0.0313
Entamoeba histolytica acetyltransferase, GNAT family 0.0056 0.0101 0.2242
Schistosoma mansoni smad 0.0015 0.0003 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0399 0.7047
Brugia malayi Latrophilin receptor protein 2 0.0198 0.0435 0.0434
Echinococcus granulosus neuropeptides capa receptor 0.0654 0.1513 0.2518
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0209 0.0462 0.0767
Schistosoma mansoni coup transcription factor 0.0031 0.0042 0.0067
Plasmodium falciparum carbonic anhydrase 0.0058 0.0106 0.064
Schistosoma mansoni myo inositol monophosphatase 0.0015 0.0004 0.0004
Brugia malayi RNA, U transporter 1 0.0055 0.0099 0.0097
Trypanosoma brucei heat shock protein, putative 0.0018 0.001 0.001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0089 0.0178 0.0811
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Schistosoma mansoni cpg binding protein 0.0132 0.028 0.0463
Brugia malayi Peptidase family M1 containing protein 0.0127 0.0269 0.0267
Brugia malayi 6-phosphofructokinase 0.0063 0.0117 0.0115
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0124 0.0261 0.0432
Echinococcus multilocularis neuropeptides capa receptor 0.0654 0.1513 0.2518
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0145 0.0311 0.2403
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0061 0.0061
Onchocerca volvulus 0.0654 0.1513 0.252
Onchocerca volvulus 0.0654 0.1513 0.252
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.0022 0.002
Trypanosoma brucei pyruvate kinase 1, putative 0.0023 0.0022 0.0022
Trichomonas vaginalis mercuric reductase, putative 0.0031 0.0041 0.0697
Brugia malayi TAR-binding protein 0.0088 0.0175 0.0173
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.006 0.0109 0.0179
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Loa Loa (eye worm) hypothetical protein 0.0058 0.0106 0.0106
Brugia malayi beta-lactamase family protein 0.0146 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.1012 0.2357 0.2357
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0041 0.0041
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0029 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0654 0.1513 0.2518
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0031 0.0041 0.127
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0133
Echinococcus granulosus vesicular acetylcholine transporter 0.2556 0.6005 1
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0311 0.0703 1
Echinococcus granulosus carbonic anhydrase 0.0058 0.0106 0.0174
Mycobacterium ulcerans glutaminase 0.0154 0.0332 0.2566
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Onchocerca volvulus 0.0654 0.1513 0.252
Echinococcus granulosus snurportin 1 0.0207 0.0458 0.076
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.1253 0.2927 0.2927
Schistosoma mansoni Smad4 0.0015 0.0003 0.0002
Onchocerca volvulus 0.0654 0.1513 0.252
Brugia malayi hypothetical protein 0.0118 0.0247 0.0245
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0015 0.0003 0.0005
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0042 0.0067
Loa Loa (eye worm) beta-lactamase 0.0146 0.0313 0.0313
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0031 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Toxoplasma gondii aminopeptidase N protein 0.0701 0.1624 1
Loa Loa (eye worm) voltage-dependent calcium channel 0.0048 0.0082 0.0082
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0062 0.0114 0.1987
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0654 0.1513 0.2518
Onchocerca volvulus 0.0654 0.1513 0.252
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.0595
Brugia malayi Tnks protein 0.0021 0.0018 0.0016
Schistosoma mansoni BC026374 protein (S09 family) 0.007 0.0133 0.0218
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.006 0.0109 0.0179
Schistosoma mansoni tar DNA-binding protein 0.0088 0.0175 0.0288
Mycobacterium ulcerans polyketide synthase 0.0016 0.0006 0.0032
Trypanosoma brucei Aminopeptidase M1, putative 0.0057 0.0102 0.0102
Loa Loa (eye worm) TYRA-2 protein 0.0654 0.1513 0.1513
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0654 0.1513 0.2518
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0019 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Echinococcus granulosus poly (ADP ribose) polymerase 0.0088 0.0176 0.0291
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0288 0.0478
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0212 0.0469 0.2878
Loa Loa (eye worm) hypothetical protein 0.0034 0.0049 0.0049
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.02 0.044 0.2017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0654 0.1513 0.2518
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0015 0.0004 0.0046
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0057 0.0102 0.0102
Mycobacterium leprae Probable lipase LipE 0.0146 0.0313 0.6265
Mycobacterium leprae Probable pyruvate kinase PykA 0.0023 0.0022 0.0409
Brugia malayi glutathione reductase 0.0089 0.0178 0.0176
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0202 0.0445 1
Brugia malayi MH1 domain containing protein 0.0033 0.0046 0.0044
Schistosoma mansoni voltage-gated cation channel 0.0075 0.0146 0.024
Trypanosoma cruzi Heat shock protein 83, putative 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.4248 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0399 0.7047
Echinococcus granulosus tm gpcr rhodopsin 0.0654 0.1513 0.2518
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0019 0.0013 0.002
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0026 0.0031 0.0048
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0042 0.007
Echinococcus granulosus lamin dm0 0.0053 0.0094 0.0153
Trypanosoma brucei DNA polymerase beta thumb, putative 0.003 0.0039 0.0039
Plasmodium falciparum transporter, putative 0.0311 0.0703 0.4324
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0654 0.1513 0.2518
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0145 0.0311 0.5489
Schistosoma mansoni sodium/chloride dependent transporter 0.0311 0.0703 0.1168
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0062 0.0101
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0654 0.1513 0.2518
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0038 0.0057 0.0057
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0029 0.0027
Echinococcus multilocularis transient receptor potential gamma protein 0.0091 0.0182 0.0301
Mycobacterium ulcerans 6-phosphofructokinase 0.0063 0.0117 0.0897
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0033
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0015 0.0004 0.0046
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0057 0.0057
Schistosoma mansoni biogenic amine (5HT) receptor 0.1084 0.2528 0.4208
Brugia malayi Dopamine receptor protein 1 0.0654 0.1513 0.1512
Mycobacterium tuberculosis Probable oxidoreductase 0.0225 0.0499 0.2292
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0042 0.0067
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0032 0.0045 0.0869
Toxoplasma gondii aminopeptidase N, putative 0.0701 0.1624 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0003 0.0002
Trypanosoma cruzi heat shock protein 85, putative 0.0018 0.001 0.001
Loa Loa (eye worm) carboxylesterase 0.007 0.0133 0.0133
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0058 0.0106 0.0104
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0046 0.0046
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0022 0.0021 0.0089
Plasmodium vivax hypothetical protein, conserved 0.0146 0.0313 0.1921
Brugia malayi conserved hypotetical protein 0.0015 0.0003 0.0001
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0023 0.0022 0.0094
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0251 0.4421
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0311 0.0703 0.1168
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0088 0.0175 0.0288
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0654 0.1513 0.1512
Echinococcus multilocularis microtubule associated protein 2 0.0445 0.1018 0.1693
Loa Loa (eye worm) inositol-1 0.0145 0.0311 0.0311
Brugia malayi MH1 domain containing protein 0.0018 0.0011 0.0009
Mycobacterium tuberculosis Probable lipase LipD 0.0146 0.0313 0.1436
Brugia malayi G-protein coupled receptor 0.0654 0.1513 0.1512
Onchocerca volvulus 0.007 0.0133 0.0221
Schistosoma mansoni Smad4 0.0033 0.0046 0.0074
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0031 0.0041 0.0041
Mycobacterium ulcerans lipase LipD 0.0146 0.0313 0.2423
Mycobacterium tuberculosis Probable dehydrogenase 0.0202 0.0446 0.2047
Echinococcus multilocularis sodium and chloride dependent glycine 0.0311 0.0703 0.1169
Schistosoma mansoni endoplasmin 0.0018 0.001 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0654 0.1513 0.2518
Echinococcus multilocularis TRP (transient receptor potential) channel 0.004 0.0062 0.0101
Schistosoma mansoni myst-related protein 0.0015 0.0003 0.0002
Schistosoma mansoni ap endonuclease 0.0039 0.0061 0.0098
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0042 0.0067
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0251 0.4421
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0654 0.1513 0.2518
Leishmania major importin beta-1 subunit, putative 0.0016 0.0005 0.0005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0013 0.0091
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0038 0.0057 0.0985
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Echinococcus granulosus smad 0.0033 0.0046 0.0075
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0124 0.0261 0.0259
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0042 0.0067
Trichomonas vaginalis heat shock protein, putative 0.0018 0.001 0.0151
Brugia malayi steroid hormone receptor 0.0031 0.0042 0.004
Echinococcus granulosus orexin receptor type 2 0.0654 0.1513 0.2518
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0042 0.0067
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0145 0.0311 0.1904
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.006 0.0109 0.0109
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0225 0.0499 0.2292
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Trypanosoma brucei heat shock protein, putative 0.0018 0.001 0.001
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0031 0.0041 0.0525
Mycobacterium ulcerans Type I modular polyketide synthase 0.0015 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0311 0.0703 0.0703
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0049 0.0078
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.0035
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.006 0.0109 0.0179
Echinococcus granulosus tm gpcr rhodopsin 0.0654 0.1513 0.2518
Echinococcus granulosus serotonin transporter 0.1012 0.2357 0.3924
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0222 0.0493 0.0493
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0063 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0654 0.1513 0.2518
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0014 0.0002 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0313 0.0313
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0031 0.0041 0.0239
Loa Loa (eye worm) thioredoxin reductase 0.0089 0.0178 0.0178
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0042 0.0067
Brugia malayi neuropeptide F receptor 0.0654 0.1513 0.1512
Schistosoma mansoni ap endonuclease 0.0039 0.0061 0.0098
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0042 0.0067
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Echinococcus multilocularis transcription factor eb 0.0061 0.0112 0.0184
Trypanosoma brucei heat shock protein, putative 0.0018 0.001 0.001
Onchocerca volvulus 0.0034 0.0049 0.0082
Echinococcus granulosus muscleblind protein 0.0178 0.0388 0.0644
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0046 0.0075
Echinococcus granulosus cpg binding protein 0.0132 0.028 0.0464
Mycobacterium ulcerans aminopeptidase N PepN 0.0038 0.0057 0.0431
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0061 0.0362
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0031 0.0041 0.0239
Trichomonas vaginalis chaperonin, putative 0.0025 0.0027 0.0448
Mycobacterium tuberculosis Probable hydrolase 0.0146 0.0313 0.1436
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.006 0.0109 0.0109
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0133
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0003 0.0005
Loa Loa (eye worm) MBCTL1 0.0037 0.0055 0.0055
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0213 0.0472 0.0472
Entamoeba histolytica hypothetical protein 0.0021 0.0018 0.0357
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Trypanosoma cruzi aminopeptidase, putative 0.0057 0.0102 0.0102
Echinococcus multilocularis Smad4 0.0033 0.0046 0.0075
Onchocerca volvulus 0.0654 0.1513 0.252
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0004
Onchocerca volvulus 0.1012 0.2357 0.3925
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0023 0.0023 0.0023
Toxoplasma gondii type I fatty acid synthase, putative 0.0017 0.0008 0.0038
Brugia malayi nuclear receptor NHR-88 0.0015 0.0003 0.0001
Echinococcus granulosus acetylcholinesterase 0.0412 0.0942 0.1567
Echinococcus granulosus biogenic amine 5HT receptor 0.0971 0.2261 0.3764
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0023 0.0374
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0003 0.0002
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0031 0.0041 0.0305
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0029 0.021
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0654 0.1513 0.2518
Brugia malayi Inositol-1 0.0145 0.0311 0.0309
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0016 0.0006 0.0082
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0061 0.0061
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0017 0.0008 0.0061
Echinococcus multilocularis smad 0.0033 0.0046 0.0075
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0042 0.0067
Echinococcus granulosus geminin 0.0844 0.1962 0.3265
Echinococcus granulosus neuropeptide Y receptor 0.0654 0.1513 0.2518
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0042 0.0067
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0251 0.4421
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0021 0.0019 0.0104
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0003 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0042 0.0067
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0156 0.0336 0.0557
Schistosoma mansoni nuclear receptor 0.0015 0.0003 0.0002
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0311 0.0703 0.1168
Trypanosoma cruzi heat shock protein 90, putative 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0146 0.0313 0.0313
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0031 0.0031
Echinococcus granulosus peptide allatostatin:somatostatin 0.0654 0.1513 0.2518
Loa Loa (eye worm) DR-78 0.0015 0.0003 0.0003
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0075 0.0146 0.0241
Schistosoma mansoni hypothetical protein 0.0844 0.1962 0.3265
Echinococcus multilocularis importin subunit beta 1 0.0019 0.0014 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.0289
Onchocerca volvulus 0.007 0.0133 0.0221
Trypanosoma cruzi trypanothione reductase, putative 0.0031 0.0041 0.0041
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0038 0.0057 0.0092
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0035 0.0035
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0075 0.0146 0.0241
Echinococcus multilocularis dnaJ subfamily B 0.1515 0.3545 0.5903
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0654 0.1513 0.2518
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.0022 0.0037
Echinococcus multilocularis protein dispatched 1 0.0026 0.003 0.0048
Loa Loa (eye worm) carboxylesterase 0.007 0.0133 0.0133
Brugia malayi Dopamine receptor 0.0654 0.1513 0.1512
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Schistosoma mansoni aldehyde dehydrogenase 0.02 0.044 0.0729
Leishmania major ATP-dependent phosphofructokinase 0.0063 0.0117 0.0117
Brugia malayi Pre-SET motif family protein 0.0034 0.0049 0.0047
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0075 0.0146 0.0241
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0014 0.0002 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0088 0.0175 0.0288
Brugia malayi Peptidase family M1 containing protein 0.0038 0.0057 0.0055
Brugia malayi nuclear receptor NHR-67 0.0015 0.0003 0.0001
Toxoplasma gondii heat shock protein 90, putative 0.0018 0.001 0.005
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Brugia malayi Probable ClpP-like protease 0.0049 0.0085 0.0083
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2046 0.48 0.7994
Schistosoma mansoni opsin-like receptor 0.0654 0.1513 0.2518
Brugia malayi beta-lactamase 0.0146 0.0313 0.0312
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0251 0.4421
Schistosoma mansoni amine GPCR 0.0654 0.1513 0.2518
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0934 0.2174 1
Toxoplasma gondii hypothetical protein 0.0036 0.0053 0.0317
Loa Loa (eye worm) hypothetical protein 0.1031 0.2402 0.2402
Onchocerca volvulus 0.0038 0.0057 0.0095
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0046 0.0074
Echinococcus granulosus para nitrobenzyl esterase 0.007 0.0133 0.0219
Loa Loa (eye worm) calcium channel 0.0075 0.0146 0.0146
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0042 0.0067
Chlamydia trachomatis pyruvate kinase 0.0023 0.0022 0.0255
Brugia malayi CXXC zinc finger family protein 0.0125 0.0263 0.0261
Echinococcus granulosus serotonin receptor 0.0654 0.1513 0.2518
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0021 0.0019 0.0382
Schistosoma mansoni transient receptor potential channel 0.0091 0.0182 0.03
Mycobacterium ulcerans hypothetical protein 0.0112 0.0233 0.1801
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0003 0.0002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0202 0.0446 0.8929
Echinococcus granulosus short transient receptor potential channel 6 0.0063 0.0117 0.0193
Schistosoma mansoni nuclear receptor 0.0015 0.0003 0.0002
Schistosoma mansoni adenoreceptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0075 0.0146 0.0146
Entamoeba histolytica hypothetical protein 0.0118 0.0247 0.5517
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0014 0.0002 0.0002
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0003 0.0001
Schistosoma mansoni opsin-like receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0228 0.4013
Echinococcus multilocularis neuropeptide receptor A26 0.1205 0.2815 0.4686
Echinococcus multilocularis serotonin receptor 0.0971 0.2261 0.3764
Toxoplasma gondii aldehyde dehydrogenase 0.02 0.044 0.2699
Echinococcus multilocularis lamin dm0 0.0053 0.0094 0.0153
Schistosoma mansoni heat shock protein 0.0018 0.001 0.0013
Mycobacterium ulcerans hypothetical protein 0.0026 0.0029 0.021
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.2556 0.6005 1
Schistosoma mansoni biogenic amine receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0146 0.0313 0.0313
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0031 0.0515
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0016 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0146 0.0313 0.1436
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0133 0.0218
Echinococcus granulosus g protein coupled receptor 0.0654 0.1513 0.2518
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0003 0.0001
Echinococcus granulosus sodium channel protein 0.0035 0.0052 0.0084
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0038 0.0057 0.0057
Brugia malayi hypothetical protein 0.0311 0.0703 0.0701
Echinococcus multilocularis survival motor neuron protein 1 0.1031 0.2402 0.3998
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0057 0.0102 0.0168
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0042 0.0067
Echinococcus multilocularis cpg binding protein 0.0132 0.028 0.0464
Echinococcus granulosus histone acetyltransferase KAT2B 0.0203 0.0448 0.0744
Loa Loa (eye worm) hypothetical protein 0.0053 0.0094 0.0094
Trichomonas vaginalis glutathione reductase, putative 0.0031 0.0041 0.0697
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0042 0.0042
Echinococcus granulosus Niemann Pick C1 protein 0.0054 0.0095 0.0156
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0654 0.1513 0.1512
Loa Loa (eye worm) tnks protein 0.0021 0.0018 0.0018
Schistosoma mansoni 6-phosphofructokinase 0.0063 0.0117 0.0192
Brugia malayi Peptidase family M1 containing protein 0.0057 0.0102 0.01
Trichomonas vaginalis inositol monophosphatase, putative 0.0145 0.0311 0.5489
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0013 0.0054
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0025 0.0027 0.056
Loa Loa (eye worm) peptidase family M1 containing protein 0.0108 0.0224 0.0224
Brugia malayi Carboxylesterase family protein 0.007 0.0133 0.0131
Loa Loa (eye worm) MH2 domain-containing protein 0.0486 0.1116 0.1116
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0031 0.0515
Brugia malayi hypothetical protein 0.0015 0.0003 0.0001
Brugia malayi Tachykinin-like peptides receptor 99D 0.0654 0.1513 0.1512
Loa Loa (eye worm) glutaminase 2 0.0154 0.0332 0.0332
Brugia malayi intermediate filament protein 0.0053 0.0094 0.0092
Schistosoma mansoni amine GPCR 0.0654 0.1513 0.2518
Trypanosoma cruzi heat shock protein 85, putative 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0017 0.0008 0.0145
Echinococcus granulosus tm gpcr rhodopsin 0.0654 0.1513 0.2518
Echinococcus multilocularis Protein lozenge 0.0059 0.0107 0.0175
Trypanosoma cruzi aminopeptidase, putative 0.0038 0.0057 0.0057
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0049 0.0079
Brugia malayi hypothetical protein 0.007 0.0133 0.0131
Loa Loa (eye worm) CXXC zinc finger family protein 0.0125 0.0263 0.0263
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0017 0.0008 0.004
Loa Loa (eye worm) hypothetical protein 0.0311 0.0703 0.0703
Loa Loa (eye worm) hypothetical protein 0.0051 0.0088 0.0088
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0101 0.0206 0.0206
Echinococcus granulosus intermediate filament protein 0.0053 0.0094 0.0153
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.006 0.0109 0.066
Echinococcus multilocularis fmrfamide receptor 0.0654 0.1513 0.2518
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0031 0.0041 0.0239
Echinococcus granulosus 6 phosphofructokinase 0.0063 0.0117 0.0192
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0015 0.0004 0.0004
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0003 0.0001
Echinococcus multilocularis neuropeptide FF receptor 2 0.0654 0.1513 0.2518
Echinococcus granulosus hypothetical protein 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0135 0.0286 0.0474
Brugia malayi MH2 domain containing protein 0.0033 0.0046 0.0044
Trichomonas vaginalis pyruvate kinase, putative 0.0023 0.0022 0.0362
Echinococcus multilocularis g protein coupled receptor 0.0654 0.1513 0.2518
Mycobacterium tuberculosis Probable monophosphatase 0.0015 0.0004 0.0012
Echinococcus granulosus G protein coupled receptor 139 0.0654 0.1513 0.2518
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0057 0.0102 0.1785
Loa Loa (eye worm) hypothetical protein 0.0625 0.1445 0.1445
Brugia malayi acetyltransferase, GNAT family protein 0.0209 0.0462 0.046
Echinococcus multilocularis voltage dependent calcium channel 0.0075 0.0146 0.0241
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0046 0.0075
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0145 0.0311 0.0311
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0026 0.0031 0.2908
Schistosoma mansoni tar DNA-binding protein 0.0088 0.0175 0.0288
Plasmodium falciparum thioredoxin reductase 0.0089 0.0178 0.1084
Giardia lamblia Pyruvate kinase 0.0023 0.0022 0.2041
Schistosoma mansoni lipoxygenase 0.0075 0.0146 0.024
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0026
Entamoeba histolytica hypothetical protein 0.0015 0.0003 0.0023
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0003 0.0002
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0038 0.0057 0.0092
Onchocerca volvulus Tankyrase homolog 0.0021 0.0018 0.003
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0112 0.0232 0.0232
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0003 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0029 0.0027
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0029 0.0029
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0048 0.0082 0.0082
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0075 0.0146 0.0241
Loa Loa (eye worm) hypothetical protein 0.0038 0.0057 0.0057
Echinococcus granulosus dro:myosuppressin receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0048 0.0082 0.0082
Loa Loa (eye worm) neuropeptide F receptor 0.0654 0.1513 0.1513
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0026 0.0031 0.0048
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0654 0.1513 0.2518
Trichomonas vaginalis hypothetical protein 0.0015 0.0004 0.0045
Toxoplasma gondii hypothetical protein 0.0311 0.0703 0.4324
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Mycobacterium ulcerans Type I modular polyketide synthase 0.0015 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Schistosoma mansoni inositol monophosphatase 0.0145 0.0311 0.0514
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0026 0.0031 0.0645
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0044 0.0071
Mycobacterium leprae conserved hypothetical protein 0.0146 0.0313 0.6265
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0041 0.0041
Mycobacterium tuberculosis Monophosphatase CysQ 0.0015 0.0004 0.0012
Echinococcus granulosus biogenic amine 5HT receptor 0.1084 0.2528 0.4208
Schistosoma mansoni intermediate filament proteins 0.0053 0.0094 0.0153
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0014 0.0002 0.0002
Onchocerca volvulus 0.021 0.0465 0.0774
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0042 0.004
Echinococcus multilocularis vesicular acetylcholine transporter 0.2556 0.6005 1
Brugia malayi mbt repeat family protein 0.0032 0.0044 0.0042
Brugia malayi Pyruvate kinase, M2 isozyme 0.0023 0.0022 0.002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0026 0.0031 0.0031
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Echinococcus granulosus pyruvate kinase 0.0023 0.0022 0.0034
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0133
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0021 0.0019 0.0017
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0017 0.0008 0.004
Plasmodium falciparum amino acid transporter, putative 0.0311 0.0703 0.4324
Echinococcus granulosus GTP binding nuclear protein Ran 0.0014 0.0002 0.0001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1012 0.2357 0.2355
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0971 0.2261 0.2261
Loa Loa (eye worm) hypothetical protein 0.2171 0.5096 0.5096
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0311 0.0703 0.4324
Echinococcus granulosus beta LACTamase domain containing family member 0.0146 0.0313 0.052
Brugia malayi hypothetical protein 0.0016 0.0007 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0017 0.0008 0.0122
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0029 0.0124
Brugia malayi tailless protein 0.0015 0.0003 0.0001
Trypanosoma cruzi pyruvate kinase 2, putative 0.0023 0.0022 0.0022
Echinococcus multilocularis carbonic anhydrase II 0.0124 0.0261 0.0432
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0399 0.7047
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0058 0.0106 0.0104
Loa Loa (eye worm) hypothetical protein 0.0311 0.0703 0.0703
Leishmania major hypothetical protein, conserved 0.0146 0.0313 0.0313
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0032 0.0044 0.007
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0057 0.0102 0.0167
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0061 0.5923
Toxoplasma gondii isocitrate dehydrogenase 0.006 0.0109 0.066
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0042 0.0067
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0027 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0003 0.0003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0654 0.1513 0.2518
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0017 0.0008 0.0061
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0075 0.0146 0.024
Echinococcus granulosus TRP transient receptor potential channel 0.004 0.0062 0.0101
Echinococcus granulosus tankyrase 0.0021 0.0018 0.0027
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Trypanosoma brucei heat shock protein 90, putative 0.0018 0.001 0.001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.006 0.0109 0.0179
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0094 0.0094
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0312 0.0706 0.0706
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0003 0.0003
Loa Loa (eye worm) norepinephrine transporter 0.1012 0.2357 0.2357
Loa Loa (eye worm) hypothetical protein 0.1253 0.2927 0.2927
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0038 0.0057 0.0092
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0004 0.0045
Trypanosoma brucei heat shock protein, putative 0.0018 0.001 0.001
Brugia malayi nuclear receptor NHR-88 0.0031 0.0042 0.004
Mycobacterium ulcerans Type I modular polyketide synthase 0.0015 0.0003 0.0015
Brugia malayi Thioredoxin reductase 0.0089 0.0178 0.0176
Echinococcus granulosus g protein coupled receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) carbonic anhydrase 3 0.0124 0.0261 0.0261
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0031 0.0029
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0004
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0042 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.0289
Onchocerca volvulus 0.0654 0.1513 0.252
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0049 0.0085 0.0649
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0029 0.021
Echinococcus granulosus g-protein coupled receptor 0.0654 0.1513 0.2518
Echinococcus granulosus Niemann Pick C1 protein 0.0077 0.0149 0.0246
Brugia malayi mothers against decapentaplegic homolog 3 0.0015 0.0003 0.0001
Onchocerca volvulus 0.0017 0.0008 0.0013
Brugia malayi G protein-coupled receptor F59B2.13 0.0654 0.1513 0.1512
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0007 0.0009
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0021 0.0019 0.0019
Echinococcus granulosus acetylcholinesterase 0.0412 0.0942 0.1567
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Trichomonas vaginalis glutaminase, putative 0.0154 0.0332 0.5863
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0042 0.0067
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0035 0.0595
Brugia malayi ecdysone receptor 0.0015 0.0003 0.0001
Onchocerca volvulus 0.0654 0.1513 0.252
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0654 0.1513 0.1513
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.0595
Brugia malayi Calcitonin receptor-like protein seb-1 0.0625 0.1445 0.1443
Entamoeba histolytica hypothetical protein 0.0021 0.0018 0.0357
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0042 0.004
Onchocerca volvulus 0.0125 0.0263 0.0438
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0057 0.0102 0.0102
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0031 0.0041 0.0181
Echinococcus multilocularis isocitrate dehydrogenase 0.006 0.0109 0.0179
Echinococcus multilocularis carbonic anhydrase 0.0058 0.0106 0.0174
Loa Loa (eye worm) hypothetical protein 0.0049 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0198 0.0435 0.0722
Toxoplasma gondii heat shock protein HSP90 0.0018 0.001 0.005
Schistosoma mansoni smad1 5 8 and 0.0033 0.0046 0.0074
Trypanosoma cruzi heat shock protein 85, putative 0.0014 0.0002 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0029 0.021
Schistosoma mansoni hypothetical protein 0.0022 0.0021 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Echinococcus granulosus peptidase Clp S14 family 0.0032 0.0045 0.0072
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0003 0.0003
Trypanosoma brucei hypothetical protein, conserved 0.0146 0.0313 0.0313
Echinococcus granulosus tachykinin peptides receptor 99D 0.0654 0.1513 0.2518
Brugia malayi MH2 domain containing protein 0.0486 0.1116 0.1114
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0031 0.0041 0.0041
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0031 0.0041 0.0239
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0042 0.004
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0094 0.0092
Echinococcus granulosus histone acetyltransferase MYST2 0.0037 0.0055 0.0088
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0063 0.0117 0.049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0042 0.0067
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0058 0.0106 0.0104
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1253 0.2927 0.4872
Plasmodium vivax glutathione reductase, putative 0.0089 0.0178 0.1084
Echinococcus granulosus lamin 0.0053 0.0094 0.0153
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0049 0.0085 0.1677
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0007 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0035 0.0595
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0145 0.0311 0.0311
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0029 0.021
Brugia malayi Pyruvate kinase, muscle isozyme 0.0023 0.0022 0.002
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0124 0.0261 0.0261
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0038 0.0057 0.0092
Loa Loa (eye worm) glutathione reductase 0.0089 0.0178 0.0178
Echinococcus granulosus poly (ADP ribose) polymerase 0.0044 0.0072 0.0118
Echinococcus multilocularis protein patched 0.0023 0.0023 0.0035
Toxoplasma gondii transporter, cation channel family protein 0.0048 0.0082 0.0496
Schistosoma mansoni vesicular amine transporter 0.0015 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0058 0.0106 0.0173
Echinococcus multilocularis peptidase Clp (S14 family) 0.0032 0.0045 0.0072
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0075 0.0146 0.0241
Echinococcus granulosus alpha 1A adrenergic receptor 0.0654 0.1513 0.2518
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Trichomonas vaginalis inositol monophosphatase, putative 0.0015 0.0004 0.0046
Echinococcus granulosus dnaJ subfamily B 0.1515 0.3545 0.5903
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.1253 0.2927 0.4873
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Brugia malayi MH1 domain containing protein 0.0018 0.0011 0.0009
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0007 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0035 0.0595
Brugia malayi Endoplasmin precursor 0.0018 0.001 0.0008
Toxoplasma gondii ABC1 family protein 0.0146 0.0313 0.1921
Loa Loa (eye worm) latrophilin receptor protein 2 0.0198 0.0435 0.0435
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0025 0.0027 0.0448
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0031 0.0041 0.0065
Schistosoma mansoni sodium/chloride dependent transporter 0.0311 0.0703 0.1168
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.0289
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0042 0.0067
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0654 0.1513 0.2518
Onchocerca volvulus Huntingtin homolog 0.0312 0.0706 0.1175
Schistosoma mansoni pyruvate kinase 0.0023 0.0022 0.0033
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0654 0.1513 0.2518
Schistosoma mansoni sodium/chloride dependent transporter 0.1012 0.2357 0.3923
Brugia malayi G-protein coupled receptor 0.0654 0.1513 0.1512
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0146 0.0313 0.0312
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0017 0.0008 0.0029
Echinococcus granulosus Smad4 0.0033 0.0046 0.0075
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.0288 0.0288
Echinococcus multilocularis histone acetyltransferase MYST2 0.0037 0.0055 0.0088
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0065 0.0122 0.02
Loa Loa (eye worm) TAR-binding protein 0.0088 0.0175 0.0175
Brugia malayi Dopamine receptor protein 2 0.0654 0.1513 0.1512
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.021 0.0465 0.0463
Echinococcus multilocularis tumor protein p63 0.0205 0.0452 0.0751
Echinococcus multilocularis acetylcholinesterase 0.0412 0.0942 0.1567
Echinococcus multilocularis voltage dependent calcium channel 0.0075 0.0146 0.0241
Mycobacterium tuberculosis Conserved protein 0.0146 0.0313 0.1436
Echinococcus granulosus GPCR family 2 0.0198 0.0435 0.0723
Loa Loa (eye worm) hypothetical protein 0.0412 0.0942 0.0942
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0014 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Brugia malayi hypothetical protein 0.0015 0.0003 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0288 0.0478
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0044 0.0071
Brugia malayi CHE-14 protein 0.0023 0.0023 0.0021
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0198 0.0435 0.0723
Loa Loa (eye worm) acetylcholinesterase 1 0.0412 0.0942 0.0942
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0042 0.0067
Giardia lamblia Heat shock protein HSP 90-alpha 0.0018 0.001 0.0854
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0017 0.0008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0061 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0156 0.0336 0.0556
Loa Loa (eye worm) acetyltransferase 0.0209 0.0462 0.0462
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0654 0.1513 0.2518
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0035 0.0595
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0202 0.0446 0.2047
Echinococcus multilocularis heat shock protein 0.0018 0.001 0.0014
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0048 0.0082 0.0082
Entamoeba histolytica hypothetical protein 0.0044 0.0072 0.1582
Trypanosoma brucei trypanothione reductase 0.0089 0.0178 0.0178
Trypanosoma brucei aminopeptidase, putative 0.0038 0.0057 0.0057
Schistosoma mansoni biogenic amine receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Loa Loa (eye worm) hypothetical protein 0.1012 0.2357 0.2357
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0042 0.004
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0057 0.0102 0.0168
Trypanosoma cruzi heat shock protein 90, putative 0.0014 0.0002 0.0002
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0145 0.0311 0.6967
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0063 0.0117 0.0117
Trichomonas vaginalis set domain proteins, putative 0.0253 0.0565 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0046 0.0075
Treponema pallidum sodium- and chloride- dependent transporter 0.1012 0.2357 1
Brugia malayi Pre-SET motif family protein 0.0222 0.0493 0.0491
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Toxoplasma gondii HEAT repeat-containing protein 0.0019 0.0014 0.0075
Schistosoma mansoni lipoxygenase 0.0053 0.0093 0.0151
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus granulosus leukotriene A 4 hydrolase 0.0038 0.0057 0.0092
Onchocerca volvulus 0.0654 0.1513 0.252
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus granulosus neuropeptide receptor 0.0654 0.1513 0.2518
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0016 0.0006 0.0032
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0015 0.0003 0.0015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0035 0.0595
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0625 0.1445 0.1445
Leishmania major C-8 sterol isomerase-like protein 0.4248 1 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0029 0.06
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0021 0.0019 0.0308
Echinococcus granulosus voltage dependent calcium channel 0.0048 0.0082 0.0135
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus multilocularis beta LACTamase domain containing family member 0.0146 0.0313 0.052
Schistosoma mansoni neuropeptide F-like receptor 0.0654 0.1513 0.2518
Brugia malayi hypothetical protein 0.0126 0.0266 0.0264
Mycobacterium ulcerans carboxylesterase, LipT 0.007 0.0133 0.102
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.007 0.0133 0.2329
Echinococcus multilocularis GPCR, family 2 0.0198 0.0435 0.0723
Loa Loa (eye worm) hypothetical protein 0.0146 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.1012 0.2357 0.2357
Schistosoma mansoni tar DNA-binding protein 0.0088 0.0175 0.0288
Loa Loa (eye worm) solute carrier family 6 member 4 0.1012 0.2357 0.2357
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus granulosus Protein patched homolog 1 0.0023 0.0023 0.0035
Brugia malayi Inositol monophosphatase family protein 0.0015 0.0004 0.0002
Schistosoma mansoni hypothetical protein 0.0022 0.0021 0.0031
Toxoplasma gondii thioredoxin reductase 0.0089 0.0178 0.1084
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0042 0.004
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0311 0.0703 0.1169
Trichomonas vaginalis phosphofructokinase, putative 0.0017 0.0008 0.0122
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0412 0.0942 0.1566
Onchocerca volvulus 0.0146 0.0313 0.0522
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0053
Brugia malayi Melatonin receptor type 1A 0.0654 0.1513 0.1512
Schistosoma mansoni carbonic anhydrase-related 0.0058 0.0106 0.0173
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0031 0.0041 0.127
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0042 0.0067
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0003 0.0003
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0146 0.0313 0.1436
Echinococcus multilocularis muscleblind protein 0.0178 0.0388 0.0644
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0135 0.0286 0.0473
Echinococcus multilocularis SAM and MBT domain containing protein 0.0032 0.0044 0.0071
Schistosoma mansoni histamine h1 receptor 0.0654 0.1513 0.2518
Echinococcus granulosus rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Brugia malayi beta-lactamase family protein 0.0146 0.0313 0.0312
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0057 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.179 0.4195 0.4195
Echinococcus multilocularis ubiquitin specific protease 41 0.0026 0.0031 0.0048
Plasmodium vivax importin-beta 2, putative 0.0019 0.0014 0.0075
Onchocerca volvulus 0.007 0.0133 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.0595
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0029 0.0045
Loa Loa (eye worm) hypothetical protein 0.0058 0.0106 0.0106
Brugia malayi latrophilin 2 splice variant baaae 0.0427 0.0978 0.0976
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0031 0.0041 0.0065
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0124 0.0261 0.0261
Loa Loa (eye worm) aminopeptidase N 0.0057 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0971 0.2261 0.2261
Onchocerca volvulus 0.0021 0.0019 0.0031
Loa Loa (eye worm) phosphofructokinase 0.0063 0.0117 0.0117
Echinococcus granulosus neuropeptides capa receptor 0.0654 0.1513 0.2518
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0049 0.0085 0.0512
Mycobacterium ulcerans polyketide synthase Pks13 0.0022 0.0021 0.015
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0075 0.0146 0.0241
Schistosoma mansoni 6-phosphofructokinase 0.0063 0.0117 0.0192
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0042 0.004
Trichomonas vaginalis glucosylceramidase, putative 0.0126 0.0266 0.469
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0015 0.0003 0.0009
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0057 0.0102 0.0168
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Echinococcus granulosus pyruvate kinase 0.0023 0.0022 0.0034
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0049 0.0079
Trypanosoma brucei Aminopeptidase M1, putative 0.0057 0.0102 0.0102
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0015 0.0003 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Echinococcus multilocularis Niemann Pick C1 protein 0.0077 0.0149 0.0246
Onchocerca volvulus 0.0146 0.0313 0.0522
Loa Loa (eye worm) glutaminase 0.0154 0.0332 0.0332
Loa Loa (eye worm) endoplasmin 0.0018 0.001 0.001
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.006 0.0109 0.0109
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0225 0.0499 0.2292
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0202 0.0446 0.2047
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0654 0.1513 0.1512
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0399 0.7047
Schistosoma mansoni smad 0.0033 0.0046 0.0074
Loa Loa (eye worm) neuropeptide F receptor 0.0654 0.1513 0.1513
Trypanosoma brucei heat shock protein, putative 0.0018 0.001 0.001
Leishmania major pyruvate kinase 0.0023 0.0022 0.0022
Mycobacterium ulcerans monophosphatase 0.0015 0.0004 0.002
Trypanosoma brucei pyruvate kinase 1 0.0023 0.0022 0.0022
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0049 0.0085 0.0512
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0031 0.0041 0.0065
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0313 0.5536
Schistosoma mansoni cellular tumor antigen P53 0.003 0.0039 0.0062
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0061 0.1324
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0061 0.0251
Brugia malayi WGR domain containing protein 0.0202 0.0445 0.0443
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0213 0.0472 0.0472
Trypanosoma brucei isocitrate dehydrogenase, putative 0.006 0.0109 0.0109
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0027 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Echinococcus granulosus transient receptor potential ion channel A 0.0078 0.0153 0.0252
Schistosoma mansoni neuropeptide receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0156 0.0336 0.0336
Schistosoma mansoni hypothetical protein 0.0654 0.1513 0.2518
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0035 0.0595
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0013 0.007
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0057 0.0102 0.0168
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0027 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0042 0.004
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0062 0.0114 0.0688
Schistosoma mansoni carbonic anhydrase-related 0.0058 0.0106 0.0173
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Mycobacterium ulcerans esterase/lipase LipP 0.0146 0.0313 0.2423
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0118 0.0247 0.0408
Loa Loa (eye worm) hypothetical protein 0.0427 0.0978 0.0978
Trypanosoma brucei heat shock protein, putative 0.0018 0.001 0.001
Echinococcus granulosus inositol monophosphatase 1 0.0145 0.0311 0.0515
Echinococcus granulosus WGR domain containing protein 0.0088 0.0176 0.0291
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0015 0.0004 0.0048
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0042 0.0067
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Loa Loa (eye worm) hypothetical protein 0.0178 0.0388 0.0388
Trichomonas vaginalis pyruvate kinase, putative 0.0023 0.0022 0.0362
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0058 0.0106 0.0106
Brugia malayi Niemann-Pick C1 protein precursor 0.0054 0.0095 0.0093
Schistosoma mansoni microtubule-associated protein tau 0.0445 0.1018 0.1692
Plasmodium vivax amine transporter, putative 0.0311 0.0703 0.4324
Schistosoma mansoni alpha-1 adrenergic receptor 0.0654 0.1513 0.2518
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0057 0.0102 0.0168
Echinococcus multilocularis sodium channel protein 0.0035 0.0052 0.0084
Plasmodium falciparum glutathione reductase 0.0089 0.0178 0.1084
Echinococcus granulosus BC026374 protein S09 family 0.007 0.0133 0.0219
Entamoeba histolytica hypothetical protein 0.0016 0.0005 0.0077
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0003 0.0002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0029 0.021
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0124 0.0261 0.0259
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0251 0.4421
Trichomonas vaginalis phosphofructokinase, putative 0.0017 0.0008 0.0122
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0124 0.0261 0.0261
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0022 0.0021 0.0089
Loa Loa (eye worm) T-complex protein 1 0.0025 0.0027 0.0027
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.007 0.0133 0.0604
Echinococcus granulosus neuropeptide Y receptor 0.0654 0.1513 0.2518
Echinococcus multilocularis g protein coupled receptor 0.0654 0.1513 0.2518
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0145 0.0311 0.5489
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.0595
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Toxoplasma gondii phosphofructokinase PFKII 0.0017 0.0008 0.004
Toxoplasma gondii hypothetical protein 0.0058 0.0106 0.064
Onchocerca volvulus Fatty acid synthase homolog 0.0027 0.0032 0.0053
Echinococcus granulosus inositol monophosphatase 0.0015 0.0004 0.0004
Trypanosoma cruzi trypanothione reductase, putative 0.0089 0.0178 0.0178
Echinococcus granulosus tar DNA binding protein 0.0088 0.0175 0.0289
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0061 0.0111 0.0111
Plasmodium falciparum pyruvate kinase 0.0023 0.0022 0.0123
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0117 0.2049
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0311 0.0703 0.1169
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0654 0.1513 0.2518
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0031 0.0031
Echinococcus multilocularis tar DNA binding protein 0.0088 0.0175 0.0289
Echinococcus multilocularis thioredoxin glutathione reductase 0.009 0.018 0.0297
Entamoeba histolytica heat shock protein 90, putative 0.0018 0.001 0.0182
Echinococcus multilocularis pyruvate kinase 0.0023 0.0022 0.0034
Loa Loa (eye worm) G-protein coupled receptor 0.0654 0.1513 0.1513
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0075 0.0146 0.0241
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0007 0.0009
Schistosoma mansoni gliotactin 0.007 0.0133 0.0218
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0625 0.1445 0.1443
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0042 0.004
Brugia malayi nuclear hormone receptor 0.0031 0.0042 0.004
Onchocerca volvulus 0.0654 0.1513 0.252
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.0289
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0016 0.0006 0.0019
Schistosoma mansoni amine GPCR 0.0968 0.2254 0.3751
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0049 0.0085 0.0512
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0014 0.0002 0.0001
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0061 0.0061
Echinococcus multilocularis neuropeptide receptor 0.0654 0.1513 0.2518
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0075 0.0146 0.024
Schistosoma mansoni hypothetical protein 0.0844 0.1962 0.3265
Echinococcus granulosus voltage dependent calcium channel 0.0075 0.0146 0.0241
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0251 0.4421
Onchocerca volvulus 0.0654 0.1513 0.252
Trichomonas vaginalis glucosylceramidase, putative 0.0126 0.0266 0.469
Onchocerca volvulus Huntingtin homolog 0.0312 0.0706 0.1175
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0061 0.0459
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0057 0.0102 0.0167
Loa Loa (eye worm) hypothetical protein 0.0467 0.1072 0.1072
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0003 0.0003
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0156 0.0336 0.0336
Echinococcus multilocularis rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0042 0.0067
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1012 0.2357 0.3923
Schistosoma mansoni cpg binding protein 0.0132 0.028 0.0463
Mycobacterium ulcerans aminopeptidase N PepN 0.0057 0.0102 0.0781
Toxoplasma gondii hypothetical protein 0.0015 0.0004 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0288 0.0477
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0013 0.0131
Echinococcus granulosus neuropeptide receptor A26 0.1205 0.2815 0.4686
Mycobacterium leprae Polyketide synthase Pks13 0.0022 0.0021 0.0387
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0049 0.0085 0.0649
Brugia malayi Smad1 0.0033 0.0046 0.0044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0042 0.004
Schistosoma mansoni hypothetical protein 0.0203 0.0448 0.0743
Mycobacterium tuberculosis Probable lipase LipE 0.0146 0.0313 0.1436
Echinococcus granulosus thioredoxin glutathione reductase 0.009 0.018 0.0297
Schistosoma mansoni peptidase Clp (S14 family) 0.0049 0.0085 0.0138
Schistosoma mansoni transcription factor LCR-F1 0.0118 0.0247 0.0407
Schistosoma mansoni endoplasmin 0.0018 0.001 0.0013
Onchocerca volvulus 0.0654 0.1513 0.252
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0016 0.0006 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0003 0.0003
Entamoeba histolytica heat shock protein 90, putative 0.0018 0.001 0.0182
Echinococcus granulosus poly (ADP ribose) polymerase 0.0044 0.0072 0.0118
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0031 0.0041 0.0305
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0046 0.0075
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0035 0.0033
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0003 0.0002
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0202 0.0445 0.0739
Echinococcus granulosus carbonic anhydrase 0.0058 0.0106 0.0174
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0003 0.0002
Schistosoma mansoni neuropeptide F-like receptor 0.0654 0.1513 0.2518
Brugia malayi GnHR receptor homolog 0.0654 0.1513 0.1512
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0042 0.004
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0654 0.1513 0.252
Onchocerca volvulus 0.0127 0.0269 0.0448
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0029 0.0543
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.0313 0.5536
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0042 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.0289
Trypanosoma brucei importin beta-1 subunit, putative 0.0019 0.0014 0.0014
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0021 0.0019 0.0019
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0037 0.0055 0.0088
Echinococcus granulosus polycomb protein SCMH1 0.0032 0.0044 0.0071
Trichomonas vaginalis phosphofructokinase, putative 0.0017 0.0008 0.0122
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus multilocularis rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Brugia malayi isocitrate dehydrogenase 0.006 0.0109 0.0107
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0399 0.7047
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0266 0.0597 0.0991
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0146 0.0313 0.1436
Echinococcus multilocularis muscleblind protein 1 0.0178 0.0388 0.0644
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0311 0.0703 0.1169
Echinococcus granulosus short transient receptor potential channel 6 0.0063 0.0117 0.0193
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0049 0.0079
Schistosoma mansoni sodium-dependent amino acid transporter 0.0311 0.0703 0.1168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0654 0.1513 0.2518
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.0005 0.0069
Onchocerca volvulus 0.0654 0.1513 0.252
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.006 0.0109 0.0178
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0031 0.0041 0.0041
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0003 0.0005
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0031 0.0041 0.0039
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0654 0.1513 0.2518
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0015 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0198 0.0435 0.0722
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0021 0.0019 0.0028
Loa Loa (eye worm) runx1 0.0059 0.0107 0.0107
Schistosoma mansoni amine GPCR 0.0654 0.1513 0.2518
Mycobacterium tuberculosis Probable oxidoreductase 0.0559 0.1289 0.5926
Loa Loa (eye worm) pyruvate kinase 0.0023 0.0022 0.0022
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0003 0.0002
Loa Loa (eye worm) serotonin transporter b 0.1012 0.2357 0.2357
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0654 0.1513 0.2518
Echinococcus multilocularis carbonic anhydrase 0.0058 0.0106 0.0174
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0654 0.1513 0.2518
Leishmania major carbonic anhydrase-like protein 0.0124 0.0261 0.0261
Schistosoma mansoni hypothetical protein 0.0022 0.0021 0.0031
Loa Loa (eye worm) RNA binding protein 0.0088 0.0175 0.0175
Plasmodium falciparum histone acetyltransferase GCN5 0.0056 0.0101 0.0613
Trypanosoma brucei heat shock protein 90, putative 0.0018 0.001 0.001
Brugia malayi phosphofructokinase 0.0063 0.0117 0.0115
Brugia malayi nuclear hormone receptor 0.0015 0.0003 0.0001
Schistosoma mansoni transient receptor potential channel 0.0063 0.0117 0.0192
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.013 0.0275 0.1258
Toxoplasma gondii exonuclease III APE 0.0039 0.0061 0.0362
Brugia malayi mbt repeat family protein 0.0032 0.0044 0.0042
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.003 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.0595
Entamoeba histolytica hypothetical protein 0.0021 0.0018 0.0357
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0027 0.0025
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0015 0.0004 0.0004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0311 0.0703 0.0701
Brugia malayi ORL1-like opioid receptor 0.0654 0.1513 0.1512
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0654 0.1513 0.2518
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0038 0.0057 0.0057
Echinococcus granulosus carbonic anhydrase II 0.0124 0.0261 0.0432
Brugia malayi Importin beta-1 subunit 0.0019 0.0014 0.0012
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0101 0.0206 0.0206
Schistosoma mansoni myosin xvIII 0.0654 0.1513 0.2518
Echinococcus granulosus rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Trypanosoma cruzi importin beta-1 subunit, putative 0.0016 0.0005 0.0005
Giardia lamblia TCP-1 chaperonin subunit beta 0.0025 0.0027 0.253
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0654 0.1513 0.2518
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0007 0.0009
Echinococcus multilocularis neuropeptide receptor 0.0654 0.1513 0.2518
Giardia lamblia NADH oxidase lateral transfer candidate 0.0031 0.0041 0.3934
Schistosoma mansoni hypothetical protein 0.0198 0.0435 0.0722
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0049 0.0078
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0133 0.0218
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0654 0.1513 0.1513
Echinococcus multilocularis acetylcholinesterase 0.0412 0.0942 0.1567
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0701 0.1624 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0049 0.0078
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0031 0.0041 0.0041
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0021 0.0019 0.0019
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0654 0.1513 0.1513
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Echinococcus multilocularis 6 phosphofructokinase 0.0063 0.0117 0.0192
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0013 0.0019
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0003 0.0003
Brugia malayi ecdysteroid receptor 0.0031 0.0042 0.004
Echinococcus granulosus poly adp ribose polymerase 2 0.0156 0.0336 0.0557
Loa Loa (eye worm) heat shock protein 90 0.0018 0.001 0.001
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Trypanosoma brucei heat shock protein, putative 0.0018 0.001 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0399 0.7047
Loa Loa (eye worm) melatonin receptor type 1A 0.0654 0.1513 0.1513
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.179 0.4195 0.4195
Schistosoma mansoni cpg binding protein 0.0125 0.0263 0.0435
Schistosoma mansoni myst-related protein 0.0015 0.0003 0.0002
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0042 0.0067
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0156 0.0336 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0018 0.0289
Onchocerca volvulus 0.007 0.0133 0.0221
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.0044 0.007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0042 0.004
Trichomonas vaginalis spcc417.12 protein, putative 0.007 0.0133 0.2329
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0038 0.0057 0.0339
Echinococcus multilocularis neuropeptide s receptor 0.1205 0.2815 0.4686
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0015 0.0004 0.0004
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0025 0.0027 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0045
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.007 0.0133 0.0219
Echinococcus granulosus sterol regulatory element binding protein 0.0023 0.0023 0.0035
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.006 0.0109 0.0495
Echinococcus multilocularis fmrfamide receptor 0.0654 0.1513 0.2518
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0075 0.0146 0.0144
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.0313 0.0519
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0042 0.0042
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0003 0.0002
Echinococcus granulosus carboxylesterase 5A 0.0412 0.0942 0.1567
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.0005 0.0069
Echinococcus granulosus sex peptide receptor 0.0654 0.1513 0.2518
Toxoplasma gondii NADPH-glutathione reductase 0.0031 0.0041 0.0239
Schistosoma mansoni neuropeptide receptor 0.0654 0.1513 0.2518
Trypanosoma brucei heat shock protein, putative 0.0018 0.001 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0014
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1084 0.2528 0.4208
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0042 0.0067
Echinococcus multilocularis short transient receptor potential channel 6 0.0063 0.0117 0.0193
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0654 0.1513 0.2518
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0061 0.1049
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0021 0.0019 0.0019
Brugia malayi MH2 domain containing protein 0.0033 0.0046 0.0044
Loa Loa (eye worm) fatty acid synthase 0.0015 0.0003 0.0003
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0014 0.0002 0.0004
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0427 0.0978 0.1625
Toxoplasma gondii histone lysine methyltransferase SET1 0.0243 0.0542 0.3329
Onchocerca volvulus 0.0654 0.1513 0.252
Echinococcus granulosus heat shock protein 90 0.0018 0.001 0.0014
Schistosoma mansoni hypothetical protein 0.0198 0.0435 0.0722
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0042 0.0067
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0029 0.021
Brugia malayi Carboxylesterase family protein 0.007 0.0133 0.0131
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0015 0.0003 0.0038
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Echinococcus multilocularis lamin 0.0053 0.0094 0.0153
Brugia malayi WGR domain containing protein 0.0156 0.0336 0.0334
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0654 0.1513 0.2518
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0654 0.1513 0.2518
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0311 0.0703 0.0701
Schistosoma mansoni lamin 0.0053 0.0094 0.0153
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0042 0.0042
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0654 0.1513 0.2518
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0025 0.0027 0.0153
Plasmodium falciparum glutathione reductase 0.0031 0.0041 0.0239
Trichomonas vaginalis glucosylceramidase, putative 0.012 0.0251 0.4421
Echinococcus granulosus sodium and chloride dependent glycine 0.0311 0.0703 0.1169
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0311 0.0703 0.1168
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0046 0.0046
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1253 0.2927 0.4872
Mycobacterium ulcerans monophosphatase CysQ 0.0015 0.0004 0.002
Schistosoma mansoni glutaminase 0.0154 0.0332 0.055
Entamoeba histolytica aminopeptidase, putative 0.0057 0.0102 0.2259
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0029 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0011 0.0043
Onchocerca volvulus 0.003 0.0039 0.0065
Plasmodium vivax heat shock protein 86, putative 0.0018 0.001 0.005
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0145 0.0311 0.0311
Brugia malayi Muscleblind-like protein 0.0178 0.0388 0.0386
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0061 0.0098
Echinococcus multilocularis Niemann Pick C1 protein 0.0054 0.0095 0.0156
Brugia malayi nuclear receptor RXR 0.0016 0.0007 0.0005
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0088 0.0175 0.0175
Brugia malayi hypothetical protein 0.0038 0.0057 0.0055
Leishmania major trypanothione reductase 0.0089 0.0178 0.0178
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Toxoplasma gondii t-complex protein beta subunit 0.0025 0.0027 0.0153
Mycobacterium ulcerans monophosphatase CysQ 0.0015 0.0004 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0041 0.0041
Brugia malayi MH1 domain containing protein 0.0033 0.0046 0.0044
Echinococcus granulosus fmrfamide receptor 0.0654 0.1513 0.2518
Onchocerca volvulus 0.0253 0.0565 0.0941
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Plasmodium falciparum heat shock protein 90 0.0018 0.001 0.005
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0049 0.029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0041 0.0041
Onchocerca volvulus 0.0015 0.0003 0.0005
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0003 0.0001
Toxoplasma gondii aminopeptidase n, putative 0.0701 0.1624 1
Schistosoma mansoni hypothetical protein 0.0207 0.0458 0.076
Echinococcus multilocularis allatostatin A receptor 0.0654 0.1513 0.2518
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0017 0.0008 0.004
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus multilocularis dro:myosuppressin receptor 0.0654 0.1513 0.2518
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0029 0.06
Echinococcus granulosus mixed lineage leukemia protein mll 0.0032 0.0044 0.0071
Brugia malayi RNA recognition motif domain containing protein 0.0088 0.0175 0.0173
Echinococcus granulosus survival motor neuron protein 1 0.1031 0.2402 0.3998
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Echinococcus granulosus poly (ADP ribose) polymerase 0.0044 0.0072 0.0118
Trichomonas vaginalis esterase, putative 0.0146 0.0313 0.5536
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0061 0.0061
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0013 0.007
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0044
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0654 0.1513 0.1512
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Mycobacterium leprae Probable monophosphatase 0.0015 0.0004 0.0052
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0015 0.0004 0.0007
Onchocerca volvulus 0.0031 0.0042 0.007
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Schistosoma mansoni sex comb on midleg homolog 0.0032 0.0044 0.007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Onchocerca volvulus 0.0026 0.0029 0.0048
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0029 0.0543
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0057 0.0102 0.0102
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.2556 0.6005 0.6005
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.003 0.0039 0.0039
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0021 0.0019 0.0029
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0133 0.0218
Loa Loa (eye worm) hypothetical protein 0.0126 0.0266 0.0266
Mycobacterium ulcerans pyruvate kinase 0.0023 0.0022 0.0158
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.0313 0.5536
Echinococcus granulosus importin subunit beta 1 0.0019 0.0014 0.0021
Trypanosoma brucei poly(adp-ribose) polymerase 0.0156 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0135 0.0286 0.0474
Loa Loa (eye worm) hypothetical protein 0.0311 0.0703 0.0703
Schistosoma mansoni aminopeptidase A (M01 family) 0.0038 0.0057 0.0092
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0031 0.0041 0.0041
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.0022 0.0037
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0117 0.2049
Loa Loa (eye worm) hypothetical protein 0.0198 0.0435 0.0435
Mycobacterium tuberculosis Conserved protein 0.0146 0.0313 0.1436
Mycobacterium ulcerans inositol-monophosphatase ImpA 0.0015 0.0004 0.002
Echinococcus multilocularis pyruvate kinase 0.0023 0.0022 0.0034
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0015 0.0004 0.0004
Schistosoma mansoni lozenge 0.0059 0.0107 0.0174
Onchocerca volvulus 0.0057 0.0102 0.017
Trichomonas vaginalis inositol monophosphatase, putative 0.0015 0.0004 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.0595
Toxoplasma gondii 6-phosphofructokinase 0.0017 0.0008 0.004
Echinococcus multilocularis orexin receptor type 2 0.0654 0.1513 0.2518
Schistosoma mansoni growth hormone secretagogue receptor 0.0654 0.1513 0.2518
Echinococcus multilocularis neuroligin 0.007 0.0133 0.0219
Trichomonas vaginalis phosphofructokinase, putative 0.0017 0.0008 0.0122
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0225 0.0499 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0039 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0042 0.0042
Echinococcus multilocularis g protein coupled receptor 0.0654 0.1513 0.2518
Brugia malayi Carboxylesterase family protein 0.007 0.0133 0.0131
Onchocerca volvulus Neuropeptide F receptor homolog 0.0654 0.1513 0.252
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.02 0.044 0.044
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0654 0.1513 0.2518
Loa Loa (eye worm) 6-phosphofructokinase 0.0063 0.0117 0.0117
Onchocerca volvulus 0.0033 0.0047 0.0079
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0049 0.0085 0.1158
Brugia malayi TATA binding protein associated factor 0.0038 0.0057 0.0055
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0207 0.0458 0.0458
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0049 0.0085 0.0354
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0029 0.021
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.02 0.044 0.073
Toxoplasma gondii hypothetical protein 0.0034 0.0049 0.0292
Brugia malayi AKH receptor 0.0654 0.1513 0.1512
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0311 0.0703 0.1169
Toxoplasma gondii hypothetical protein 0.0311 0.0703 0.4324
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0311 0.0703 0.1168
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0049 0.0085 0.1158
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0124 0.0261 0.0432
Schistosoma mansoni smad1 5 8 and 0.0033 0.0046 0.0074
Toxoplasma gondii isocitrate dehydrogenase 0.006 0.0109 0.066
Schistosoma mansoni aldehyde dehydrogenase 0.02 0.044 0.0729
Schistosoma mansoni neuropeptide receptor 0.0654 0.1513 0.2518
Echinococcus granulosus neuropeptide FF receptor 2 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0071 0.0135 0.0135
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0035 0.0595
Brugia malayi Transient-receptor-potential like protein 0.004 0.0062 0.006
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0003 0.0003
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0014 0.0002 0.0002
Echinococcus multilocularis carbonic anhydrase 0.0058 0.0106 0.0174
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Brugia malayi hypothetical protein 0.0654 0.1513 0.1512
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0288 0.0477
Brugia malayi Inositol monophosphatase family protein 0.0015 0.0004 0.0002
Entamoeba histolytica hypothetical protein 0.0118 0.0247 0.5517
Loa Loa (eye worm) hypothetical protein 0.0412 0.0942 0.0942
Leishmania major heat shock protein 83-1 0.0018 0.001 0.001
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0032 0.0044 0.0071
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0182 0.0399 0.0397
Schistosoma mansoni neuroligin 3 (S09 family) 0.007 0.0133 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.0595
Mycobacterium ulcerans aldehyde dehydrogenase 0.02 0.044 0.3404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Loa Loa (eye worm) G-protein coupled receptor 0.0654 0.1513 0.1513
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0049 0.0085 0.0139
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0011 0.0043
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0021 0.0019 0.0104
Trypanosoma brucei C-8 sterol isomerase, putative 0.4248 1 1
Brugia malayi putative neuropeptide receptor 0.0654 0.1513 0.1512
Entamoeba histolytica phosphofructokinase, putative 0.0063 0.0117 0.2595
Mycobacterium tuberculosis Conserved protein 0.0146 0.0313 0.1436
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0031 0.0041 0.0239
Loa Loa (eye worm) hypothetical protein 0.0311 0.0703 0.0703
Echinococcus multilocularis G protein coupled receptor 139 0.0654 0.1513 0.2518
Schistosoma mansoni inositol monophosphatase 0.0145 0.0311 0.0514
Echinococcus multilocularis rhodopsin orphan GPCR 0.0654 0.1513 0.2518
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0037 0.0055 0.0088
Echinococcus multilocularis short transient receptor potential channel 6 0.0063 0.0117 0.0193
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0031 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus granulosus heat shock protein 0.0018 0.001 0.0014
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0003 0.0002
Echinococcus granulosus expressed conserved protein 0.005 0.0087 0.0143
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0041 0.0041
Schistosoma mansoni pap-inositol-14-phosphatase 0.0015 0.0004 0.0004
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0146 0.0313 0.0313
Schistosoma mansoni vesicular acetylcholine transporter 0.2556 0.6005 1
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0061 0.0059
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0042 0.0067
Echinococcus multilocularis neuropeptides capa receptor 0.0654 0.1513 0.2518
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0017 0.0008 0.0122
Trichomonas vaginalis helicase, putative 0.0028 0.0035 0.0595
Loa Loa (eye worm) hypothetical protein 0.0312 0.0706 0.0706
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0654 0.1513 0.2518
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0311 0.0703 0.4324
Loa Loa (eye worm) hypothetical protein 0.0178 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0654 0.1513 0.2518
Loa Loa (eye worm) hypothetical protein 0.0146 0.0313 0.0313
Trichomonas vaginalis phosphofructokinase, putative 0.0017 0.0008 0.0122
Schistosoma mansoni hypothetical protein 0.021 0.0465 0.0771
Schistosoma mansoni survival motor neuron protein 0.021 0.0465 0.0771
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0288 0.0478
Trypanosoma brucei importin beta-1 subunit, putative 0.0019 0.0014 0.0014
Plasmodium vivax pyruvate kinase, putative 0.0023 0.0022 0.0123
Echinococcus granulosus neuroligin 0.007 0.0133 0.0219
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0019 0.0017
Brugia malayi putative neuropeptide receptor NPR1 0.0654 0.1513 0.1512
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0015 0.0003 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0011 0.0043
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0042 0.0042
Trypanosoma cruzi pyruvate kinase 2, putative 0.0023 0.0022 0.0022
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0019 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.0654 0.1513 0.1513
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.1253 0.2927 0.4873
Loa Loa (eye worm) hypothetical protein 0.0091 0.0182 0.0182
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0026 0.0031 0.0048
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0198 0.0435 0.0434
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0061 0.1049
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0042 0.0067
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0031 0.0515
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0021 0.0019 0.0029
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0042 0.0042
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0003 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.007 0.0133 0.0133
Toxoplasma gondii pyruvate kinase PyK1 0.0023 0.0022 0.0123

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 0 % GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM ChEMBL. 20485427
Inhibition (functional) = 0 % GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM ChEMBL. 20485427
Inhibition (functional) = 0.37 % ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro ChEMBL. No reference
Inhibition (functional) = 0.54 % ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro ChEMBL. No reference
Inhibition (functional) = 1.21 % ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro ChEMBL. No reference
Inhibition (functional) = 26 % GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. ChEMBL. 20485427
Inhibition (functional) = 100 % GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM ChEMBL. 20485427
Inhibition frequency index (IFI) (functional) = 3.52 Inhibition Frequency Index (IFI) GSK. 20485427
Percent growth inhibition (functional) = -1 % Percent inhibition of P. falciparum Dd2 growth (at 2 uM) GSK. 20485427
Percent growth inhibition (functional) = 0 % Percent inhibition of P. falciparum lactate dehydrogenase activity (at 2 uM) GSK. 20485427
Percent growth inhibition (functional) = 26 % Percent inhibition of HepG2 growth (at 10 uM) GSK. 20485427
Percent growth inhibition (functional) = 100 % Percent inhibition of P. falciparum 3D7 growth (at 2 uM) GSK. 20485427
XC50 (functional) = 6.06 XC50 determination of P. falciparum 3D7 growth GSK. 20485427
XC50 (functional) = 0.86777 uM GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. ChEMBL. 20485427

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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