Detailed information for compound 675809

Basic information

Technical information
  • TDR Targets ID: 675809
  • Name: 9-(5-chloro-2-prop-2-ynoxyphenyl)-3,3,6,6-tet ramethyl-4,5,7,9-tetrahydro-2H-xanthene-1,8-d ione
  • MW: 438.943 | Formula: C26H27ClO4
  • H donors: 0 H acceptors: 2 LogP: 4.68 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C#CCOc1ccc(cc1C1C2=C(OC3=C1C(=O)CC(C3)(C)C)CC(CC2=O)(C)C)Cl
  • InChi: 1S/C26H27ClO4/c1-6-9-30-19-8-7-15(27)10-16(19)22-23-17(28)11-25(2,3)13-20(23)31-21-14-26(4,5)12-18(29)24(21)22/h1,7-8,10,22H,9,11-14H2,2-5H3
  • InChiKey: DCFTYIGRTLMJLM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 9-(5-chloro-2-prop-2-ynoxy-phenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-xanthene-1,8-dione
  • 9-(5-chloro-2-propargyloxy-phenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-xanthene-1,8-quinone
  • ZINC03000036
  • STK082499

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) beta-lactamase 0.0099 0.0243 0.0732
Schistosoma mansoni smad1 5 8 and 0.0028 0.0033 0.0077
Echinococcus multilocularis cpg binding protein 0.0161 0.0422 0.0422
Onchocerca volvulus 0.0044 0.008 0.0311
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0034 0.0053 0.0122
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0044 0.008 0.0185
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0074 0.0223
Schistosoma mansoni terminal deoxycytidyl transferase 0.0042 0.0074 0.0172
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.000000012346 0.000000047957
Toxoplasma gondii target of rapamycin (TOR), putative 0.0044 0.0081 0.0314
Echinococcus multilocularis survival motor neuron protein 1 0.0357 0.0996 0.0996
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0019 0.0007 0.0017
Onchocerca volvulus 0.0044 0.008 0.0311
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0042 0.0074 0.0074
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0059 0.0125 0.1412
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0162 0.0425 0.0425
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0028 0.0033 0.0077
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0306 0.0847 0.1963
Brugia malayi Isocitrate dehydrogenase 0.0056 0.0117 0.0354
Schistosoma mansoni hypothetical protein 0.0016 0 0.0001
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0306 0.0847 0.2553
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.008 0.0185
Echinococcus multilocularis BC026374 protein (S09 family) 0.0195 0.0521 0.0521
Onchocerca volvulus 0.0195 0.0521 0.2025
Trichomonas vaginalis chaperonin, putative 0.0019 0.0007 0.0028
Plasmodium falciparum histone acetyltransferase GCN5 0.0036 0.0056 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0081 0.0314
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.008 0.008
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0117 0.0293 0.0293
Trichomonas vaginalis spcc417.12 protein, putative 0.0195 0.0521 0.2025
Echinococcus granulosus ring and YY1 binding protein 0.0319 0.0885 0.1268
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.0074 0.0288
Trypanosoma brucei trypanothione reductase 0.0151 0.0392 0.4429
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0038 0.0064 0.0194
Echinococcus granulosus neuropeptide receptor 0.0044 0.008 0.0115
Echinococcus granulosus lamin dm0 0.0058 0.0122 0.0174
Onchocerca volvulus 0.0145 0.0375 0.1455
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.008 0.0115
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0162 0.0425 0.0609
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0162 0.0425 0.1281
Onchocerca volvulus 0.0195 0.0521 0.2025
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0059 0.0125 0.1412
Brugia malayi Nuclear hormone receptor-like 1 0.0162 0.0425 0.1281
Echinococcus multilocularis nuclear receptor nhr 48 0.0145 0.0375 0.0375
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0019 0.0007 0.0082
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0056 0.0117 0.0456
Echinococcus granulosus X box binding protein 1 0.0241 0.0655 0.0939
Brugia malayi nuclear receptor RXR 0.0145 0.0375 0.1129
Loa Loa (eye worm) hypothetical protein 0.0261 0.0713 0.215
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0105 0.1184
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.008 0.0185
Plasmodium falciparum T-complex protein 1 subunit beta 0.0019 0.0007 0.0028
Onchocerca volvulus 0.0058 0.0122 0.0473
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Brugia malayi Nuclear hormone receptor E75 0.0145 0.0375 0.1129
Brugia malayi Niemann-Pick C1 protein precursor 0.0082 0.0193 0.0581
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0434 0.1219 0.3672
Schistosoma mansoni cpg binding protein 0.0161 0.0422 0.0977
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0145 0.0375 0.0537
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0104 0.0257 0.0257
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0104 0.0257 0.0998
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni RNA binding protein 0.0319 0.0885 0.2051
Loa Loa (eye worm) thioredoxin reductase 0.0151 0.0392 0.1181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0046 0.0177
Brugia malayi neuropeptide F receptor 0.0044 0.008 0.0241
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0134 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0052 0.0105 0.0243
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0145 0.0375 0.1455
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0319 0.0885 0.3438
Brugia malayi glutathione reductase 0.0151 0.0392 0.1181
Loa Loa (eye worm) hypothetical protein 0.0162 0.0425 0.1281
Entamoeba histolytica heat shock transcription factor, putative 0.0065 0.0142 0.6071
Schistosoma mansoni tar DNA-binding protein 0.0181 0.048 0.1112
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.008 0.0185
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0019 0.0007 0.0028
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0182 0.0483 0.1119
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Schistosoma mansoni TRABID protein (C64 family) 0.0319 0.0885 0.2051
Plasmodium vivax histone acetyltransferase GCN5, putative 0.004 0.0071 0.0275
Mycobacterium tuberculosis Conserved protein 0.0099 0.0243 0.0367
Echinococcus multilocularis sterol regulatory element binding protein 0.0035 0.0056 0.0056
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0044 0.008 0.0241
Brugia malayi hypothetical protein 0.0162 0.0425 0.1281
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0319 0.0885 1
Brugia malayi Dopamine receptor protein 1 0.0971 0.2786 0.8396
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0068 0.0206
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0078 0.018
Schistosoma mansoni importin beta-1 0.0018 0.0006 0.0015
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0323 0.4579
Brugia malayi Zinc finger protein 183 homolog 0.0016 0 0.0001
Echinococcus granulosus geminin 0.1199 0.3454 0.4947
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.008 0.0185
Trypanosoma cruzi DNA repair protein, putative 0.0022 0.0016 0.0179
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.008 0.008
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0195 0.0521 0.1208
Echinococcus granulosus polycomb protein SCMH1 0.0034 0.0053 0.0076
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0044 0.008 0.0185
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0052 0.0105 0.0407
Echinococcus granulosus thyroid hormone receptor alpha 0.0145 0.0375 0.0537
Echinococcus granulosus intermediate filament protein 0.0058 0.0122 0.0174
Onchocerca volvulus 0.0898 0.2574 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Brugia malayi Bromodomain containing protein 0.0031 0.0044 0.0132
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0056 0.0117 0.0117
Entamoeba histolytica heat shock transcription factor, putative 0.0065 0.0142 0.6071
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0028 0.0033 0.1422
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0059 0.0125 0.0125
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0099 0.0243 0.0367
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0248 0.0676 0.2035
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0052 0.0105 0.1184
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0248 0.0676 0.2035
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.008 0.008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0052 0.0203
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0171 0.0663
Echinococcus granulosus inositol monophosphatase 1 0.0021 0.0015 0.0021
Onchocerca volvulus 0.0099 0.0243 0.0943
Schistosoma mansoni hypothetical protein 0.0044 0.008 0.0185
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0021 0.0015 0.0057
Loa Loa (eye worm) hypothetical protein 0.0217 0.0587 0.1769
Leishmania major cytochrome p450-like protein 0.0028 0.0036 0.0402
Brugia malayi hypothetical protein 0.019 0.0508 0.153
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.008 0.0185
Loa Loa (eye worm) hypothetical protein 0.0357 0.0996 0.3001
Echinococcus granulosus neuroligin 0.0195 0.0521 0.0747
Brugia malayi Carboxylesterase family protein 0.0195 0.0521 0.1571
Loa Loa (eye worm) hypothetical protein 0.0016 0.000000012346 0.000000037199
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0094
Echinococcus granulosus BC026374 protein S09 family 0.0195 0.0521 0.0747
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0306 0.0847 0.2553
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0319 0.0885 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0306 0.0847 0.1214
Echinococcus granulosus neuropeptide FF receptor 2 0.0044 0.008 0.0115
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.008 0.0185
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0044 0.008 0.008
Plasmodium vivax thioredoxin reductase, putative 0.0151 0.0392 0.1523
Echinococcus granulosus GPCR family 2 0.0137 0.0353 0.0506
Toxoplasma gondii ABC1 family protein 0.0099 0.0243 0.0943
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.005 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0306 0.0847 0.2553
Echinococcus multilocularis beta LACTamase domain containing family member 0.0099 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus granulosus smad 0.0028 0.0033 0.0047
Brugia malayi isocitrate dehydrogenase 0.0056 0.0117 0.0354
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Brugia malayi Serotonin receptor 0.0044 0.008 0.0241
Mycobacterium ulcerans hypothetical protein 0.0099 0.0243 0.3384
Brugia malayi brahma associated protein 60 kDa 0.0898 0.2574 0.7757
Loa Loa (eye worm) hypothetical protein 0.1153 0.3319 1
Trichomonas vaginalis helicase, putative 0.0034 0.0052 0.0203
Loa Loa (eye worm) hypothetical protein 0.0306 0.0847 0.2553
Brugia malayi N-terminal motif family protein 0.0261 0.0713 0.215
Mycobacterium tuberculosis Probable reductase 0.0343 0.0955 0.1479
Schistosoma mansoni inositol monophosphatase 0.0021 0.0015 0.0034
Schistosoma mansoni smad1 5 8 and 0.0028 0.0033 0.0077
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.008 0.0241
Brugia malayi neuropeptide F receptor 0.0044 0.008 0.0241
Echinococcus granulosus mixed lineage leukemia protein mll 0.0041 0.0073 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0306 0.0847 0.2553
Onchocerca volvulus 0.0319 0.0885 0.3438
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.008 0.0185
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0074 0.0837
Schistosoma mansoni hypothetical protein 0.0137 0.0353 0.0818
Echinococcus granulosus g protein coupled receptor 0.0044 0.008 0.0115
Echinococcus multilocularis allatostatin A receptor 0.0044 0.008 0.008
Loa Loa (eye worm) nuclear receptor NHR-67 0.0145 0.0375 0.1129
Loa Loa (eye worm) RiNg Finger protein family member 0.0016 0 0.0001
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0084 0.0196 0.0455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0046 0.0177
Echinococcus granulosus dna polymerase eta 0.0042 0.0074 0.0106
Echinococcus granulosus acetylcholinesterase 0.1153 0.3319 0.4754
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0025 0.0024 0.0273
Toxoplasma gondii isocitrate dehydrogenase 0.0056 0.0117 0.0456
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0125 0.0486
Trypanosoma brucei unspecified product 0.0029 0.0036 0.0411
Onchocerca volvulus 0.0044 0.008 0.0311
Onchocerca volvulus 0.0306 0.0847 0.3291
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0898 0.2574 0.2574
Mycobacterium tuberculosis Probable oxidoreductase 0.0382 0.1067 0.1654
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0078 0.018
Mycobacterium tuberculosis Probable hydrolase 0.0099 0.0243 0.0367
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0127 0.0323 0.0493
Echinococcus granulosus beta LACTamase domain containing family member 0.0099 0.0243 0.0348
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0105 0.1184
Schistosoma mansoni hypothetical protein 0.0296 0.0818 0.1895
Loa Loa (eye worm) hypothetical protein 0.0058 0.0122 0.0367
Echinococcus granulosus ecdysone induced protein 78C 0.0306 0.0847 0.1214
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0016 0 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.008 0.0185
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0306 0.0847 0.1214
Brugia malayi RNA binding protein 0.0181 0.048 0.1446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0081 0.0314
Trypanosoma brucei DNA polymerase eta, putative 0.0042 0.0074 0.0837
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0081 0.0314
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus granulosus tar DNA binding protein 0.0181 0.048 0.0688
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.009 0.0215 0.0647
Loa Loa (eye worm) carboxylesterase 0.0195 0.0521 0.1571
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0006 0.0024
Brugia malayi photoreceptor-specific nuclear receptor 0.0306 0.0847 0.2553
Brugia malayi T-complex protein 1, beta subunit 0.0019 0.0007 0.0022
Trypanosoma cruzi WLM domain containing protein, putative 0.0319 0.0885 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0036 0.0411
Entamoeba histolytica deoxycytidyl transferase, putative 0.0042 0.0074 0.3177
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0145 0.0375 0.0868
Treponema pallidum recombinase A 0.007 0.0158 0.0913
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0707 0.2017 0.6078
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0122 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.009 0.0349
Echinococcus multilocularis snurportin 1 0.0197 0.0528 0.0528
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.001 0.0117
Loa Loa (eye worm) CXXC zinc finger family protein 0.0151 0.0393 0.1183
Echinococcus granulosus Nuclear hormone receptor HR96 0.0145 0.0375 0.0537
Onchocerca volvulus 0.0319 0.0885 0.3438
Leishmania major hypothetical protein, conserved 0.0016 0.000000012346 0.00000013947
Plasmodium vivax glutathione reductase, putative 0.0151 0.0392 0.1523
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Trypanosoma brucei unspecified product 0.0029 0.0036 0.0411
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0044 0.008 0.008
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0898 0.2574 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0104 0.0257 0.0595
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Brugia malayi hypothetical protein 0.0032 0.0045 0.0135
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0044 0.008 0.0241
Echinococcus multilocularis FTZ F1 alpha 0.0306 0.0847 0.0847
Schistosoma mansoni fusion 0.0319 0.0885 0.2051
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0026 0.0037
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0306 0.0847 0.1963
Echinococcus multilocularis acetylcholinesterase 0.1153 0.3319 0.3319
Echinococcus multilocularis adam 0.0032 0.0045 0.0045
Echinococcus multilocularis X box binding protein 1 0.0241 0.0655 0.0655
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0028 0.0033 0.1862
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0016 0.000000012346 0.000000047957
Leishmania major hypothetical protein, conserved 0.0319 0.0885 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.008 0.008
Schistosoma mansoni cpg binding protein 0.0151 0.0393 0.091
Trypanosoma brucei unspecified product 0.0042 0.0074 0.0837
Schistosoma mansoni hypothetical protein 0.0137 0.0353 0.0818
Echinococcus multilocularis inositol monophosphatase 1 0.0021 0.0015 0.0015
Schistosoma mansoni Smad4 0.0028 0.0033 0.0077
Schistosoma mansoni coup transcription factor 0.0306 0.0847 0.1963
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0022 0.0016 0.0179
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.005 0.01 0.01
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0099 0.0243 0.0562
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0052 0.0203
Mycobacterium ulcerans carboxylesterase, LipT 0.0195 0.0521 0.7514
Brugia malayi Cytochrome P450 family protein 0.0028 0.0036 0.0107
Giardia lamblia Kinase, NEK 0.0016 0.000000012346 0.00000069359
Echinococcus multilocularis mothers against decapentaplegic 5 0.0028 0.0033 0.0033
Brugia malayi YY1-associated factor 2 0.0319 0.0885 0.2667
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0117 0.0293 0.068
Onchocerca volvulus 0.0044 0.008 0.0311
Mycobacterium leprae Conserved hypothetical protein 0.0744 0.2124 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.01
Echinococcus multilocularis tumor protein p63 0.2407 0.6981 0.6981
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0052 0.0105 0.1184
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.008 0.0115
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0099 0.0243 0.0732
Brugia malayi hypothetical protein 0.0162 0.0425 0.1281
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0021 0.0015 0.0164
Schistosoma mansoni cpg binding protein 0.0161 0.0422 0.0977
Entamoeba histolytica acetyltransferase, GNAT family 0.0036 0.0056 0.2414
Trypanosoma brucei hypothetical protein, conserved 0.0319 0.0885 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0034 0.0049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0052 0.0203
Echinococcus granulosus dna polymerase kappa 0.0042 0.0074 0.0106
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0033 0.0129
Mycobacterium ulcerans beta-lactamase 0.0099 0.0243 0.3384
Loa Loa (eye worm) latrophilin receptor protein 2 0.0137 0.0353 0.1064
Loa Loa (eye worm) hypothetical protein 0.0195 0.0521 0.1571
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.008 0.0115
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0306 0.0847 0.1214
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0043 0.013
Schistosoma mansoni tar DNA-binding protein 0.0181 0.048 0.1112
Trichomonas vaginalis conserved hypothetical protein 0.0898 0.2574 1
Trypanosoma cruzi hypothetical protein, conserved 0.0319 0.0885 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.001 0.0031
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0055 0.0114 0.0164
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0019 0.0007 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.008 0.0185
Brugia malayi putative neuropeptide receptor NPR1 0.0044 0.008 0.0241
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0319 0.0885 0.2667
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0306 0.0847 0.2553
Trypanosoma cruzi hypothetical protein, conserved 0.0319 0.0885 1
Loa Loa (eye worm) hypothetical protein 0.009 0.0215 0.0647
Schistosoma mansoni alpha-1 adrenergic receptor 0.0044 0.008 0.0185
Loa Loa (eye worm) hypothetical protein 0.0352 0.0981 0.2957
Leishmania major hypothetical protein, conserved 0.0319 0.0885 1
Echinococcus multilocularis muscleblind protein 0.0217 0.0587 0.0587
Toxoplasma gondii LsmAD domain-containing protein 0.0075 0.0171 0.0663
Plasmodium falciparum thioredoxin reductase 0.0151 0.0392 0.1523
Schistosoma mansoni lipoxygenase 0.0052 0.0104 0.0242
Echinococcus granulosus Protein patched homolog 1 0.0035 0.0056 0.008
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0052 0.0105 0.1339
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0162 0.0425 0.0985
Brugia malayi Carboxylesterase family protein 0.1153 0.3319 1
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Onchocerca volvulus 0.0073 0.0165 0.0642
Schistosoma mansoni opsin-like receptor 0.0044 0.008 0.0185
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0898 0.2574 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0041 0.0073 0.0104
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0434 0.1219 0.3672
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0035
Brugia malayi Bromodomain containing protein 0.0067 0.0147 0.0443
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0306 0.0847 0.2553
Trichomonas vaginalis ankyrin, putative 0.0016 0.000000012346 0.000000047957
Schistosoma mansoni Replicative DNA helicase 0.0252 0.0689 0.1596
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0044 0.008 0.0241
Echinococcus multilocularis neuropeptide receptor A26 0.1336 0.3853 0.3853
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0312
Toxoplasma gondii aldehyde dehydrogenase 0.0127 0.0323 0.1256
Schistosoma mansoni myelin transcription factor 1 myt1 0.0039 0.0067 0.0154
Brugia malayi brahma associated protein 60 kDa 0.0898 0.2574 0.7757
Schistosoma mansoni myst-related protein 0.0019 0.0009 0.002
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0018 0.0005 0.0005
Schistosoma mansoni intermediate filament proteins 0.0058 0.0122 0.0282
Schistosoma mansoni mind bomb 0.0016 0.000000012346 0.000000028602
Brugia malayi nuclear receptor NHR-88 0.0145 0.0375 0.1129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0052 0.0203
Leishmania major DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Wolbachia endosymbiont of Brugia malayi recombinase A 0.007 0.0158 0.213
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0044 0.008 0.0115
Schistosoma mansoni cellular tumor antigen P53 0.0352 0.0981 0.2273
Schistosoma mansoni BC026374 protein (S09 family) 0.0195 0.0521 0.1208
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.008 0.0185
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0047 0.009 0.1015
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Echinococcus granulosus para nitrobenzyl esterase 0.0195 0.0521 0.0747
Brugia malayi Kinesin motor domain containing protein 0.0062 0.0134 0.0404
Plasmodium vivax hypothetical protein, conserved 0.0898 0.2574 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0021 0.0015 0.0057
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0306 0.0847 0.0847
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0035 0.0056 0.0168
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Loa Loa (eye worm) hypothetical protein 0.0319 0.0885 0.2667
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0319 0.0885 1
Plasmodium falciparum thioredoxin reductase 0.0052 0.0105 0.0407
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.002 0.001 0.0117
Schistosoma mansoni myosin xvIII 0.0044 0.008 0.0185
Loa Loa (eye worm) hypothetical protein 0.0319 0.0885 0.2667
Schistosoma mansoni opsin-like receptor 0.0044 0.008 0.0185
Brugia malayi nuclear receptor NHR-88 0.0306 0.0847 0.2553
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0248 0.0676 0.1565
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.008 0.0241
Onchocerca volvulus Huntingtin homolog 0.019 0.0508 0.1972
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0052 0.0203
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0056 0.0117 0.0168
Echinococcus granulosus G protein coupled receptor 139 0.0044 0.008 0.0115
Giardia lamblia Histone acetyltransferase GCN5 0.0036 0.0056 0.3161
Trichomonas vaginalis D-aminoacylase, putative 0.0099 0.0243 0.0943
Onchocerca volvulus 0.0319 0.0885 0.3438
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0055 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.008 0.008
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0074 0.017 0.017
Entamoeba histolytica hypothetical protein 0.0096 0.0233 1
Echinococcus multilocularis microtubule associated protein 2 0.1495 0.4316 0.4316
Loa Loa (eye worm) histone methyltransferase 0.005 0.01 0.03
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0145 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Brugia malayi Calcitonin receptor-like protein seb-1 0.0434 0.1219 0.3672
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0319 0.0885 0.1268
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0056 0.0117 0.0171
Trichomonas vaginalis bromodomain-containing protein, putative 0.004 0.0071 0.0275
Echinococcus granulosus sex peptide receptor 0.0044 0.008 0.0115
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0052 0.0203
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0319 0.0885 0.3438
Echinococcus granulosus muscleblind protein 0.0217 0.0587 0.0841
Echinococcus multilocularis G-protein coupled receptor, putative 0.0044 0.008 0.008
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0044 0.008 0.0185
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.008 0.0115
Schistosoma mansoni dihydroceramide desaturase 0.0018 0.0005 0.0013
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0042 0.0074 0.0223
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.008 0.0241
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0043 0.013
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0018 0.0005 0.0013
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0039 0.0067 0.0067
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.002 0.001 0.0024
Brugia malayi AKH receptor 0.0044 0.008 0.0241
Echinococcus multilocularis sex peptide receptor 0.0044 0.008 0.008
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0145 0.0375 0.1129
Schistosoma mansoni hypothetical protein 0.0034 0.0052 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0056 0.0216
Brugia malayi Melatonin receptor type 1A 0.0044 0.008 0.0241
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0052 0.0105 0.1184
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Plasmodium falciparum glutathione reductase 0.0151 0.0392 0.1523
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0052 0.0105 0.1339
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0898 0.2574 0.7757
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.001 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0105 0.1184
Schistosoma mansoni survival motor neuron protein 0.0073 0.0165 0.0383
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0059 0.0125 0.1412
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0056 0.0117 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0028 0.0033 0.0047
Loa Loa (eye worm) hypothetical protein 0.0099 0.0243 0.0732
Echinococcus granulosus kinesin family 1 0.0479 0.1351 0.1935
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0044 0.008 0.0241
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0137 0.0353 0.0506
Brugia malayi Carboxylesterase family protein 0.0195 0.0521 0.1571
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0081 0.0314
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0044 0.008 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0104 0.0257 0.0595
Schistosoma mansoni hypothetical protein 0.0898 0.2574 0.5964
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0068 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0081 0.0314
Brugia malayi RNA recognition motif domain containing protein 0.0181 0.048 0.1446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0125 0.0486
Schistosoma mansoni neuropeptide receptor 0.0044 0.008 0.0185
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0052 0.0105 0.0151
Onchocerca volvulus 0.0052 0.0106 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0065 0.0251
Loa Loa (eye worm) DR-78 0.0145 0.0375 0.1129
Giardia lamblia DINP protein human, muc B family 0.0042 0.0074 0.416
Loa Loa (eye worm) hypothetical protein 0.0099 0.0243 0.0732
Chlamydia trachomatis SWIB complex protein 0.0898 0.2574 1
Schistosoma mansoni tar DNA-binding protein 0.0181 0.048 0.1112
Brugia malayi orphan nuclear receptor NR2E1 0.0145 0.0375 0.1129
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0044 0.008 0.0241
Mycobacterium ulcerans lipase LipD 0.0099 0.0243 0.3384
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0343 0.0955 0.1479
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0145 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0099 0.0243 0.0732
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0306 0.0847 0.1963
Loa Loa (eye worm) MBCTL1 0.0039 0.0067 0.0201
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0033 0.0375
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.008 0.0185
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0248 0.0676 0.1565
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus multilocularis zinc finger protein Ran binding 0.0319 0.0885 0.0885
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0252 0.0689 1
Brugia malayi Dopamine receptor protein 2 0.0044 0.008 0.0241
Echinococcus multilocularis SWI:SNF matrix associated 0.0898 0.2574 0.2574
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0019 0.0007 0.0017
Leishmania major hypothetical protein, conserved 0.0099 0.0243 0.2743
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0096 0.0233 0.0233
Echinococcus multilocularis carboxylesterase 5A 0.1153 0.3319 0.3319
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Brugia malayi hypothetical protein 0.0521 0.1472 0.4436
Loa Loa (eye worm) hypothetical protein 0.0075 0.0171 0.0514
Loa Loa (eye worm) hypothetical protein 0.0306 0.0847 0.2553
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0203
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0044 0.008 0.0185
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.009 0.0349
Toxoplasma gondii HEAT repeat-containing protein 0.0018 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus granulosus histone acetyltransferase KAT2B 0.004 0.0071 0.0101
Echinococcus multilocularis neuroligin 0.0195 0.0521 0.0521
Brugia malayi Pre-SET motif family protein 0.0104 0.0257 0.0774
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0077 0.0178 0.0691
Echinococcus multilocularis orexin receptor type 2 0.0044 0.008 0.008
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.002 0.001 0.0117
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0306 0.0847 0.2553
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0162 0.0425 0.0985
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0042 0.0074 0.0172
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.001 0.0117
Schistosoma mansoni retinoic acid receptor RXR 0.0306 0.0847 0.1963
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0044 0.008 0.008
Onchocerca volvulus 0.0034 0.0053 0.0205
Echinococcus multilocularis histone acetyltransferase MYST2 0.0039 0.0067 0.0067
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0382 0.1067 0.1654
Echinococcus multilocularis muscleblind protein 1 0.0217 0.0587 0.0587
Brugia malayi conserved hypotetical protein 0.0145 0.0375 0.1129
Echinococcus granulosus allatostatin A receptor 0.0044 0.008 0.0115
Echinococcus granulosus dro:myosuppressin receptor 0.0044 0.008 0.0115
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Brugia malayi SET domain containing protein 0.0017 0.0002 0.0007
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0099 0.0243 0.0732
Onchocerca volvulus 0.0195 0.0521 0.2025
Brugia malayi beta-lactamase family protein 0.0099 0.0243 0.0732
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni nuclear hormone receptor 0.0145 0.0375 0.0868
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0323 0.4579
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0056 0.0117 0.0117
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0034 0.0034
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0323 0.4579
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0027 0.0061
Schistosoma mansoni patched 1 0.0035 0.0056 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0203
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0248 0.0676 0.0676
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0041 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0235
Onchocerca volvulus 0.0044 0.008 0.0311
Loa Loa (eye worm) hypothetical protein 0.0195 0.0521 0.1571
Schistosoma mansoni biogenic amine receptor 0.0044 0.008 0.0185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0306 0.0847 0.2553
Loa Loa (eye worm) hypothetical protein 0.0306 0.0847 0.2553
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.008 0.0115
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0052 0.0106 0.0245
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0306 0.0847 0.1214
Mycobacterium tuberculosis Probable dehydrogenase 0.0343 0.0955 0.1479
Brugia malayi nuclear receptor RXR 0.0162 0.0425 0.1281
Schistosoma mansoni hypothetical protein 0.0044 0.008 0.0185
Loa Loa (eye worm) steroid hormone receptor 0.0306 0.0847 0.2553
Trichomonas vaginalis ankyrin, putative 0.0016 0.000000012346 0.000000047957
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0044 0.008 0.0241
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0052 0.0105 0.1184
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0103
Loa Loa (eye worm) hypothetical protein 0.0052 0.0106 0.0318
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni hypothetical protein 0.136 0.3924 0.9091
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0026 0.0029 0.0029
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0028 0.0033 0.0033
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0056 0.0117 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0036 0.0411
Schistosoma mansoni nuclear receptor nhr-48 0.0145 0.0375 0.0868
Echinococcus multilocularis para nitrobenzyl esterase 0.0195 0.0521 0.0521
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0059 0.0125 0.1412
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Toxoplasma gondii thioredoxin reductase 0.0151 0.0392 0.1523
Echinococcus multilocularis Niemann Pick C1 protein 0.0118 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0099 0.0243 0.0732
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.008 0.008
Echinococcus multilocularis isocitrate dehydrogenase 0.0056 0.0117 0.0117
Echinococcus granulosus SAM and MBT domain containing protein 0.0034 0.0053 0.0076
Leishmania major hypothetical protein, conserved 0.0075 0.0171 0.1928
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0306 0.0847 0.2553
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0306 0.0847 0.2553
Onchocerca volvulus 0.0044 0.008 0.0311
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0065 0.0142 0.055
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0323 0.0749
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0046 0.0177
Echinococcus multilocularis fmrfamide receptor 0.0044 0.008 0.008
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0052 0.0105 0.1339
Schistosoma mansoni neuropeptide receptor 0.0044 0.008 0.0185
Brugia malayi RE15519p 0.0044 0.008 0.0241
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0033 0.0375
Echinococcus granulosus snurportin 1 0.0197 0.0528 0.0756
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.008 0.0185
Schistosoma mansoni hypothetical protein 0.0034 0.0052 0.012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0105 0.1184
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0343 0.0955 0.4475
Schistosoma mansoni transcription factor LCR-F1 0.0096 0.0233 0.054
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0036 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0203
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus multilocularis GPCR, family 2 0.0137 0.0353 0.0353
Brugia malayi Steroid receptor seven-up type 2 0.0306 0.0847 0.2553
Toxoplasma gondii kinesin motor domain-containing protein 0.0062 0.0134 0.0521
Schistosoma mansoni opsin-like receptor 0.0044 0.008 0.0185
Brugia malayi steroid hormone receptor 0.0306 0.0847 0.2553
Echinococcus granulosus histone lysine methyltransferase setb 0.0117 0.0293 0.042
Echinococcus multilocularis disintegrin and metalloproteinase 0.0018 0.0005 0.0005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0074 0.0103
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0073 0.0165 0.0498
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0068 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0203
Schistosoma mansoni lipoxygenase 0.0074 0.017 0.0393
Loa Loa (eye worm) hypothetical protein 0.0082 0.0193 0.0581
Leishmania major hypothetical protein, conserved 0.0319 0.0885 1
Echinococcus granulosus transcription factor eb 0.009 0.0216 0.0309
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.008 0.008
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.008 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.001 0.004
Echinococcus granulosus alpha 1A adrenergic receptor 0.0044 0.008 0.0115
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0018 0.0005 0.0008
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0137 0.0353 0.0506
Echinococcus multilocularis ring and YY1 binding protein 0.0319 0.0885 0.0885
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0068 0.0098
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0036 0.0107
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Trichomonas vaginalis esterase, putative 0.0099 0.0243 0.0943
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0099 0.0243 0.0367
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0635 0.1807 0.2809
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0052 0.0105 0.1184
Loa Loa (eye worm) hypothetical protein 0.0057 0.0119 0.0358
Schistosoma mansoni amine GPCR 0.0044 0.008 0.0185
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0105 0.1184
Echinococcus granulosus g protein coupled receptor 0.0044 0.008 0.0115
Schistosoma mansoni hypothetical protein 0.0197 0.0528 0.1223
Echinococcus multilocularis musashi 0.0058 0.0122 0.0122
Onchocerca volvulus 0.0044 0.008 0.0311
Echinococcus multilocularis transcription factor eb 0.009 0.0216 0.0216
Echinococcus multilocularis serotonin receptor 0.0044 0.008 0.008
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0077 0.0178 0.0691
Loa Loa (eye worm) inositol-1 0.0021 0.0015 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0306 0.0847 0.2553
Schistosoma mansoni hypothetical protein 0.0137 0.0353 0.0818
Onchocerca volvulus 0.0352 0.0981 0.3812
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0306 0.0847 0.2553
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0039 0.0067 0.0201
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0016 0.000000012346 0.000000047957
Schistosoma mansoni acetylcholinesterase 0.0195 0.0521 0.1208
Onchocerca volvulus 0.0044 0.008 0.0311
Brugia malayi Tachykinin-like peptides receptor 99D 0.0044 0.008 0.0241
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0195 0.0521 0.0802
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Plasmodium vivax hypothetical protein, conserved 0.0099 0.0243 0.0943
Schistosoma mansoni tar DNA-binding protein 0.0181 0.048 0.1112
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0195 0.0521 0.1208
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Loa Loa (eye worm) reprolysin 0.0018 0.0005 0.0016
Toxoplasma gondii t-complex protein beta subunit 0.0019 0.0007 0.0028
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.008 0.0115
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0306 0.0847 0.0847
Loa Loa (eye worm) mbt repeat family protein 0.0034 0.0053 0.0159
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.002 0.001 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0056 0.0216
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Brugia malayi RNA, U transporter 1 0.0052 0.0106 0.0319
Loa Loa (eye worm) acetylcholinesterase 1 0.1153 0.3319 1
Trypanosoma cruzi trypanothione reductase, putative 0.0151 0.0392 0.4429
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0044 0.008 0.0185
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni sex comb on midleg homolog 0.0034 0.0053 0.0122
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0074 0.0103
Loa Loa (eye worm) transcription factor SMAD2 0.0405 0.1135 0.3419
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0059 0.0125 0.029
Brugia malayi sulfakinin receptor protein 0.0044 0.008 0.0241
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0041 0.0073 0.0169
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.001 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0105 0.1184
Schistosoma mansoni gliotactin 0.0195 0.0521 0.1208
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0056 0.0117 0.1325
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0044 0.008 0.0311
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Loa Loa (eye worm) RNA binding protein 0.0181 0.048 0.1446
Mycobacterium tuberculosis Probable lipase LipE 0.0099 0.0243 0.0367
Entamoeba histolytica kinesin, putative 0.0062 0.0134 0.5757
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.008 0.008
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0171 0.0663
Brugia malayi acetyltransferase, GNAT family protein 0.0134 0.0342 0.1032
Echinococcus granulosus adam 0.0032 0.0045 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Onchocerca volvulus 0.0044 0.008 0.0311
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0074 0.017 0.0243
Echinococcus multilocularis Niemann Pick C1 protein 0.0082 0.0193 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0068 0.0265
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0062 0.024
Brugia malayi MH2 domain containing protein 0.0405 0.1135 0.3419
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus granulosus adam 17 protease 0.02 0.0536 0.0767
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.004 0.0071 0.0275
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0319 0.0885 0.3438
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0052 0.0105 0.0407
Loa Loa (eye worm) TYRA-2 protein 0.0044 0.008 0.0241
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0306 0.0847 0.2553
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0077 0.0178 0.0691
Treponema pallidum replicative DNA helicase (dnaB) 0.0252 0.0689 1
Onchocerca volvulus 0.0044 0.008 0.0311
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0028 0.0033 0.0047
Mycobacterium tuberculosis Probable lipase LipD 0.0099 0.0243 0.0367
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0019 0.0007 0.0082
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0343 0.0955 0.1479
Schistosoma mansoni histamine h1 receptor 0.0044 0.008 0.0185
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.008 0.0115
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Giardia lamblia Ser/Thr protein kinase 0.0016 0.000000012346 0.00000069359
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0044 0.008 0.008
Schistosoma mansoni smad1 5 8 and 0.0028 0.0033 0.0077
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0044 0.008 0.0185
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0426
Brugia malayi nuclear hormone receptor 0.0145 0.0375 0.1129
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0162 0.0425 0.1281
Trypanosoma cruzi WLM domain containing protein, putative 0.0319 0.0885 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.002 0.001 0.0117
Loa Loa (eye worm) hypothetical protein 0.0434 0.1219 0.3672
Loa Loa (eye worm) hypothetical protein 0.0306 0.0847 0.2553
Brugia malayi hypothetical protein 0.0096 0.0233 0.0702
Echinococcus granulosus Niemann Pick C1 protein 0.0082 0.0193 0.0276
Loa Loa (eye worm) hypothetical protein 0.0306 0.0847 0.2553
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0319 0.0885 0.2667
Echinococcus multilocularis acetylcholinesterase 0.1153 0.3319 0.3319
Schistosoma mansoni amine GPCR 0.0044 0.008 0.0185
Brugia malayi Pre-SET motif family protein 0.0707 0.2017 0.6078
Loa Loa (eye worm) hypothetical protein 0.0035 0.0056 0.0168
Loa Loa (eye worm) hypothetical protein 0.0195 0.0521 0.1571
Loa Loa (eye worm) hypothetical protein 0.0195 0.0521 0.1571
Brugia malayi hypothetical protein 0.0075 0.0171 0.0514
Mycobacterium leprae Probable lipase LipE 0.0099 0.0243 0.1109
Brugia malayi ORL1-like opioid receptor 0.0044 0.008 0.0241
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0248 0.0676 0.0676
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0052 0.0105 0.0407
Loa Loa (eye worm) MH2 domain-containing protein 0.0405 0.1135 0.3419
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0248 0.0676 0.0968
Loa Loa (eye worm) hypothetical protein 0.0099 0.0243 0.0732
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Loa Loa (eye worm) glutathione reductase 0.0151 0.0392 0.1181
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0145 0.0375 0.1455
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0033 0.0129
Loa Loa (eye worm) hypothetical protein 0.003 0.0039 0.0118
Brugia malayi Cytochrome P450 family protein 0.0028 0.0036 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.008 0.0115
Trichomonas vaginalis ion channel nompc, putative 0.0016 0.000000012346 0.000000047957
Echinococcus multilocularis SWI:SNF matrix associated 0.0898 0.2574 0.2574
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.008 0.0115
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0034 0.0053 0.0205
Onchocerca volvulus 0.0058 0.0122 0.0473
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1153 0.3319 0.7689
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0059 0.0125 0.1412
Trypanosoma brucei hypothetical protein, conserved 0.0319 0.0885 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0152 0.0395 0.0566
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.009 0.0349
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0074 0.0223
Echinococcus granulosus mothers against decapentaplegic 5 0.0028 0.0033 0.0047
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0137 0.0353 0.0353
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0306 0.0847 0.2553
Brugia malayi hypothetical protein 0.0195 0.0521 0.1571
Echinococcus multilocularis g protein coupled receptor 0.0044 0.008 0.008
Echinococcus granulosus Niemann Pick C1 protein 0.0118 0.0296 0.0424
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0074 0.0882
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0056 0.0117 0.0456
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0248 0.0676 0.0968
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0056 0.0117 0.1325
Brugia malayi beta-lactamase family protein 0.0099 0.0243 0.0732
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.008 0.0115
Echinococcus multilocularis lamin 0.0058 0.0122 0.0122
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0382 0.1067 0.5004
Giardia lamblia TCP-1 chaperonin subunit beta 0.0019 0.0007 0.0406
Loa Loa (eye worm) hypothetical protein 0.0319 0.0885 0.2667
Schistosoma mansoni kinesin eg-5 0.0062 0.0134 0.0311
Brugia malayi nuclear receptor NHR-67 0.0145 0.0375 0.1129
Loa Loa (eye worm) kinesin-like protein KLP2 0.0062 0.0134 0.0404
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0077 0.0178 0.0691
Echinococcus granulosus tachykinin peptides receptor 99D 0.0044 0.008 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0056 0.0216
Mycobacterium tuberculosis Probable esterase LipL 0.0099 0.0243 0.0367
Schistosoma mansoni hypothetical protein 0.0137 0.0353 0.0818
Loa Loa (eye worm) phosphatidylinositol 3 0.0059 0.0125 0.0377
Schistosoma mansoni tar DNA-binding protein 0.0181 0.048 0.1112
Schistosoma mansoni hypothetical protein 0.0034 0.0052 0.012
Echinococcus granulosus lamin 0.0058 0.0122 0.0174
Schistosoma mansoni neuropeptide receptor 0.0044 0.008 0.0185
Trichomonas vaginalis penicillin-binding protein, putative 0.0099 0.0243 0.0943
Toxoplasma gondii histone lysine methyltransferase SET1 0.0294 0.0812 0.3153
Toxoplasma gondii isocitrate dehydrogenase 0.0056 0.0117 0.0456
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni inositol monophosphatase 0.0021 0.0015 0.0034
Onchocerca volvulus 0.0804 0.2301 0.8938
Echinococcus multilocularis thioredoxin glutathione reductase 0.0152 0.0395 0.0395
Schistosoma mansoni hypothetical protein 0.0211 0.0569 0.1319
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Loa Loa (eye worm) carboxylesterase 0.1153 0.3319 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0044 0.008 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.001 0.004
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0181 0.048 0.1446
Onchocerca volvulus 0.0521 0.1472 0.5719
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0898 0.2574 0.3688
Schistosoma mansoni hypothetical protein 0.0096 0.0233 0.054
Plasmodium vivax importin-beta 2, putative 0.0018 0.0006 0.0025
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0018 0.0005 0.0013
Schistosoma mansoni growth hormone secretagogue receptor 0.0044 0.008 0.0185
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0137 0.0353 0.1064
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0195 0.0521 0.0802
Brugia malayi Nuclear hormone receptor-like 1 0.0162 0.0425 0.1281
Mycobacterium tuberculosis Conserved protein 0.0099 0.0243 0.0367
Loa Loa (eye worm) MH1 domain-containing protein 0.0028 0.0033 0.01
Brugia malayi intermediate filament protein 0.0058 0.0122 0.0367
Onchocerca volvulus Huntingtin homolog 0.019 0.0508 0.1972
Brugia malayi Carboxylesterase family protein 0.1153 0.3319 1
Brugia malayi ecdysteroid receptor 0.0306 0.0847 0.2553
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0086 0.0203 0.0203
Echinococcus granulosus survival motor neuron protein 1 0.0357 0.0996 0.1427
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.008 0.008
Echinococcus multilocularis protein patched 0.0035 0.0056 0.0056
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.008 0.0241
Plasmodium falciparum kinesin-5 0.0062 0.0134 0.0521
Schistosoma mansoni biogenic amine receptor 0.0044 0.008 0.0185
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0052 0.0105 0.0407
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0306 0.0847 0.0847
Mycobacterium tuberculosis Conserved protein 0.0099 0.0243 0.0367
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0042 0.0074 0.0106
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0044 0.008 0.008
Brugia malayi Inositol-1 0.0021 0.0015 0.0044
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0059 0.0125 0.1412
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.004 0.0071 0.0275
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0127 0.0323 0.0463
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.01 0.0388
Entamoeba histolytica hypothetical protein 0.0096 0.0233 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0028 0.0033 0.0033
Chlamydia trachomatis recombinase RecA 0.007 0.0158 0.0216
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0021 0.0015 0.0057
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0171 0.1928
Echinococcus multilocularis polycomb protein SCMH1 0.0034 0.0053 0.0053
Echinococcus multilocularis importin subunit beta 1 0.0018 0.0006 0.0006
Leishmania major T-complex protein 1, beta subunit, putative 0.0019 0.0007 0.0082
Echinococcus granulosus importin subunit beta 1 0.0018 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0079 0.0237
Echinococcus granulosus zinc finger protein Ran binding 0.0319 0.0885 0.1268
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0306 0.0847 0.2553
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0077 0.0178 1
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Schistosoma mansoni amine GPCR 0.0044 0.008 0.0185
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.008 0.0185
Trypanosoma brucei importin beta-1 subunit, putative 0.0018 0.0006 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0081 0.0314
Loa Loa (eye worm) hypothetical protein 0.0521 0.1472 0.4436
Loa Loa (eye worm) hypothetical protein 0.0382 0.1067 0.3215
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0021 0.0015 0.0164
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Brugia malayi Nuclear hormone receptor-like 1 0.0306 0.0847 0.2553
Echinococcus multilocularis geminin 0.1199 0.3454 0.3454
Schistosoma mansoni adenoreceptor 0.0044 0.008 0.0185
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0028 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.008 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0306 0.0847 0.2553
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0097 0.0236 0.0339
Echinococcus multilocularis neuropeptide s receptor 0.1336 0.3853 0.3853
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.008 0.008
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.0074 0.0837
Onchocerca volvulus 0.0319 0.0885 0.3438
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0036 0.0107
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0052 0.0105 0.0105
Onchocerca volvulus 0.0151 0.0393 0.1525
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0203
Schistosoma mansoni sex comb on midleg homolog 0.0034 0.0053 0.0122
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0145 0.0375 0.0868
Giardia lamblia GTOR 0.0059 0.0125 0.7024
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0203
Loa Loa (eye worm) hypothetical protein 0.1153 0.3319 1
Echinococcus granulosus neuropeptide receptor A26 0.1336 0.3853 0.5519
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0306 0.0847 0.2553
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0026 0.006
Echinococcus granulosus sterol regulatory element binding protein 0.0035 0.0056 0.008
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0197 0.0528 0.159
Echinococcus granulosus Zinc finger RanBP2 type 0.0319 0.0885 0.1268
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0145 0.0375 0.1129
Echinococcus multilocularis neuropeptide receptor 0.0044 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0898 0.2574 0.5964
Trypanosoma cruzi hypothetical protein, conserved 0.0099 0.0243 0.2743
Trypanosoma brucei hypothetical protein, conserved 0.0099 0.0243 0.2743
Echinococcus granulosus L aminoadipate semialdehyde 0.0052 0.0106 0.0151
Echinococcus multilocularis SAM and MBT domain containing protein 0.0034 0.0053 0.0053
Plasmodium falciparum importin beta, putative 0.0018 0.0006 0.0025
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Brugia malayi G-protein coupled receptor 0.0044 0.008 0.0241
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0319 0.0885 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0046 0.0177
Echinococcus granulosus g protein coupled receptor 0.0044 0.008 0.0115
Schistosoma mansoni neuropeptide receptor 0.0044 0.008 0.0185
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0032 0.0045 0.0104
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni nuclear hormone receptor 0.0306 0.0847 0.1963
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0021 0.0015 0.0164
Brugia malayi Muscleblind-like protein 0.0217 0.0587 0.1769
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.001 0.0031
Schistosoma mansoni hypothetical protein 0.0073 0.0165 0.0383
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.001 0.004
Schistosoma mansoni neuropeptide f receptor 76f 0.0044 0.008 0.0185
Brugia malayi MH2 domain containing protein 0.0028 0.0033 0.01
Brugia malayi hypothetical protein 0.0048 0.0093 0.0281
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0039 0.0067 0.0095
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0059 0.0125 0.0377
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0306 0.0847 0.0847
Echinococcus granulosus FTZ F1 alpha 0.0306 0.0847 0.1214
Schistosoma mansoni hypothetical protein 0.0034 0.0052 0.012
Loa Loa (eye worm) hypothetical protein 0.0033 0.0049 0.0147
Brugia malayi Latrophilin receptor protein 2 0.0137 0.0353 0.1064
Echinococcus multilocularis dna polymerase eta 0.0042 0.0074 0.0074
Onchocerca volvulus 0.0195 0.0521 0.2025
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0036 0.0411
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0306 0.0847 0.3291
Mycobacterium ulcerans recombinase A 0.007 0.0158 0.213
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0044 0.008 0.0115
Schistosoma mansoni nuclear receptor 0.0145 0.0375 0.0868
Trichomonas vaginalis glutathione reductase, putative 0.0052 0.0105 0.0407
Echinococcus multilocularis g protein coupled receptor 0.0044 0.008 0.008
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0019 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0033 0.0129
Echinococcus multilocularis g protein coupled receptor 0.0044 0.008 0.008
Trypanosoma brucei PAB1-binding protein , putative 0.0075 0.0171 0.1928
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.009 0.0349
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.0074 0.0288
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0052 0.0105 0.1339
Echinococcus granulosus somatostatin receptor 0.0044 0.008 0.0115
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0077 0.0178 0.0412
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0019 0.0007 0.0017
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0082 0.0193 0.8269
Echinococcus granulosus neuropeptide s receptor 0.1336 0.3853 0.5519
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0306 0.0847 0.1963
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.000000012346 0.000000047957
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0096 0.0233 0.0334
Onchocerca volvulus Bile acid receptor homolog 0.0306 0.0847 0.3291
Onchocerca volvulus 0.0099 0.0243 0.0943
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0145 0.0375 0.0537
Loa Loa (eye worm) TAR-binding protein 0.0181 0.048 0.1446
Brugia malayi hypothetical protein 0.0016 0.000000012346 0.000000037199
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Trichomonas vaginalis mercuric reductase, putative 0.0052 0.0105 0.0407
Schistosoma mansoni hypothetical protein 0.0417 0.1169 0.2709
Brugia malayi Smad1 0.0028 0.0033 0.01
Brugia malayi beta-lactamase 0.0099 0.0243 0.0732
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0028 0.0033 0.0375
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0026 0.0029 0.0042
Trypanosoma cruzi target of rapamycin kinase 3 0.0047 0.009 0.1015
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0114 0.0285 0.0285
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0127 0.0323 0.0323
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0074 0.0837
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0046 0.0177
Mycobacterium tuberculosis Carboxylesterase LipT 0.0195 0.0521 0.0802
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.002 0.001 0.001
Echinococcus granulosus g-protein coupled receptor 0.0044 0.008 0.0115
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0319 0.0885 0.2667
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0134 0.0342 0.0793
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.008 0.0115
Echinococcus granulosus tumor protein p63 0.2407 0.6981 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0052 0.0203
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0306 0.0847 0.1214
Entamoeba histolytica hypothetical protein 0.0096 0.0233 1
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0122 0.0367
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0195 0.0521 0.0521
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0319 0.0885 1
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0203
Leishmania major trypanothione reductase 0.0151 0.0392 0.4429
Plasmodium vivax ataxin-2 like protein, putative 0.0075 0.0171 0.0663
Toxoplasma gondii ran binding protein 0.0319 0.0885 0.3438
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0052 0.0105 0.015
Loa Loa (eye worm) hypothetical protein 0.0117 0.0293 0.0884
Trypanosoma cruzi hypothetical protein, conserved 0.0099 0.0243 0.2743
Echinococcus multilocularis neuropeptide receptor 0.0044 0.008 0.008
Entamoeba histolytica heat shock transcription factor, putative 0.0065 0.0142 0.6071
Schistosoma mansoni brg-1 associated factor 0.0898 0.2574 0.5964
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.008 0.0115
Giardia lamblia NADH oxidase lateral transfer candidate 0.0052 0.0105 0.589
Trichomonas vaginalis hypothetical protein 0.0018 0.0006 0.0024
Brugia malayi putative neuropeptide receptor 0.0044 0.008 0.0241
Brugia malayi nuclear hormone receptor family member nhr-6 0.0145 0.0375 0.1129
Echinococcus granulosus hypothetical protein 0.0044 0.008 0.0115
Onchocerca volvulus 0.0099 0.0243 0.0943
Schistosoma mansoni zinc finger protein 0.0145 0.0375 0.0868
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0077 0.0178 0.0691
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Echinococcus granulosus disintegrin and metalloproteinase 0.0018 0.0005 0.0008
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0319 0.0885 1
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.009 0.0216 0.065
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0044 0.008 0.0241
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0105 0.1184
Onchocerca volvulus 0.0044 0.008 0.0311
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0127 0.0323 0.3654
Leishmania major hypothetical protein, conserved 0.0319 0.0885 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0056 0.0117 0.1325
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0028 0.0033 0.0077
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0044 0.008 0.0241
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0099 0.0243 0.3384
Schistosoma mansoni hypothetical protein 0.0044 0.008 0.0185
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0145 0.0375 0.0375
Brugia malayi mbt repeat family protein 0.0034 0.0053 0.0159
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0319 0.0885 1
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0195 0.0521 0.0747
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Loa Loa (eye worm) T-complex protein 1 0.0019 0.0007 0.0022
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0036 0.0402
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0028 0.0034 0.0385
Echinococcus granulosus 7TM GPCR rhodopsin 0.0044 0.008 0.0115
Brugia malayi MH2 domain containing protein 0.0028 0.0033 0.01
Brugia malayi ecdysone receptor 0.0145 0.0375 0.1129
Loa Loa (eye worm) hypothetical protein 0.0162 0.0425 0.1281
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.008 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.008 0.0115
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0052 0.0105 0.1184
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0086 0.0203 0.0612
Mycobacterium ulcerans esterase/lipase LipP 0.0099 0.0243 0.3384
Echinococcus multilocularis expressed conserved protein 0.0077 0.0178 0.0178
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0059 0.0125 0.5363
Echinococcus multilocularis tar DNA binding protein 0.0181 0.048 0.048
Echinococcus multilocularis lamin dm0 0.0058 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0217 0.0587 0.1769
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.005 0.01 0.0143
Loa Loa (eye worm) hypothetical protein 0.0319 0.0885 0.2667
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0047 0.009 0.1015
Onchocerca volvulus 0.0017 0.0002 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0203
Echinococcus multilocularis dnaJ subfamily B 0.136 0.3924 0.3924
Brugia malayi nuclear hormone receptor 0.0306 0.0847 0.2553
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0052 0.0105 0.0316
Loa Loa (eye worm) melatonin receptor type 1A 0.0044 0.008 0.0241
Brugia malayi Carboxylesterase family protein 0.0195 0.0521 0.1571
Loa Loa (eye worm) MH2 domain-containing protein 0.0028 0.0033 0.01
Echinococcus granulosus zinc finger protein 0.0026 0.0029 0.0041
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.004 0.0071 0.0275
Echinococcus granulosus expressed conserved protein 0.0077 0.0178 0.0255
Mycobacterium leprae conserved hypothetical protein 0.0099 0.0243 0.1109
Brugia malayi MH1 domain containing protein 0.0028 0.0033 0.01
Entamoeba histolytica hypothetical protein 0.0019 0.0009 0.0367
Echinococcus granulosus ubiquitin specific protease 41 0.0028 0.0033 0.0047
Echinococcus granulosus acetylcholinesterase 0.1153 0.3319 0.4754
Echinococcus granulosus orexin receptor type 2 0.0044 0.008 0.0115
Onchocerca volvulus 0.0044 0.008 0.0311
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0052 0.0105 0.1184
Loa Loa (eye worm) isocitrate dehydrogenase 0.0056 0.0117 0.0354
Brugia malayi Nuclear hormone receptor E75 0.0145 0.0375 0.1129
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Loa Loa (eye worm) carboxylesterase 0.0195 0.0521 0.1571
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0055 0.0114 0.0114
Echinococcus granulosus cpg binding protein 0.0161 0.0422 0.0604
Echinococcus granulosus carboxylesterase 5A 0.1153 0.3319 0.4754
Plasmodium vivax kinesin-5 0.0062 0.0134 0.0521
Echinococcus multilocularis kinesin family 1 0.0479 0.1351 0.1351
Brugia malayi hypothetical protein 0.0357 0.0996 0.3001
Loa Loa (eye worm) hypothetical protein 0.0195 0.0521 0.1571
Loa Loa (eye worm) hypothetical protein 0.0099 0.0243 0.0732
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0059 0.0125 0.5363
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0319 0.0885 0.2667
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0306 0.0847 0.1214
Chlamydia trachomatis DNA topoisomerase I 0.0898 0.2574 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0382 0.1067 0.1654
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.008 0.0185
Echinococcus multilocularis zinc finger protein 0.0026 0.0029 0.0029
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0122 0.0367
Echinococcus multilocularis ubiquitin specific protease 41 0.0028 0.0033 0.0033
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0306 0.0847 0.0847
Brugia malayi hypothetical protein 0.0145 0.0375 0.1129
Echinococcus granulosus microtubule associated protein 2 0.1495 0.4316 0.6183
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0056 0.0117 0.1325
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0074 0.0837
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0019
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0171 0.1928
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.008 0.008
Brugia malayi CHE-14 protein 0.0035 0.0056 0.0168
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0323 0.0749
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Loa Loa (eye worm) twinkle helicase 0.0072 0.0163 0.0491
Chlamydia trachomatis replicative DNA helicase 0.0252 0.0689 0.2366
Brugia malayi Thioredoxin reductase 0.0151 0.0392 0.1181
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0052 0.0105 0.1184
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0261 0.0713 0.2771
Schistosoma mansoni smad 0.0028 0.0033 0.0077
Trichomonas vaginalis set domain proteins, putative 0.0804 0.2301 0.8938
Brugia malayi tailless protein 0.0145 0.0375 0.1129
Brugia malayi F/Y-rich N-terminus family protein 0.0051 0.0102 0.0307
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0056 0.0117 0.0117
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0306 0.0847 0.0847
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0145 0.0375 0.0375
Brugia malayi hypothetical protein 0.0044 0.008 0.0241
Echinococcus granulosus serotonin receptor 0.0044 0.008 0.0115
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.203 0.588 0.9171
Schistosoma mansoni hypothetical protein 0.1199 0.3454 0.8001
Trypanosoma cruzi hypothetical protein, conserved 0.0319 0.0885 1
Onchocerca volvulus 0.0104 0.0257 0.0998
Echinococcus granulosus Nuclear hormone receptor HR96 0.0145 0.0375 0.0537
Toxoplasma gondii NADPH-glutathione reductase 0.0052 0.0105 0.0407
Schistosoma mansoni amine GPCR 0.0044 0.008 0.0185
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0319 0.0885 0.2667
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0195 0.0521 0.1208
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0052 0.0106 0.0318
Brugia malayi G protein-coupled receptor F59B2.13 0.0044 0.008 0.0241
Schistosoma mansoni zinc finger protein 0.0319 0.0885 0.2051
Brugia malayi nuclear hormone receptor family member odr-7 0.0145 0.0375 0.1129
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0086 0.0203 0.0291
Echinococcus multilocularis adam 17 protease 0.0182 0.0483 0.0483
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Brugia malayi latrophilin 2 splice variant baaae 0.0296 0.0818 0.2465
Schistosoma mansoni neuroligin 3 (S09 family) 0.0195 0.0521 0.1208
Loa Loa (eye worm) hypothetical protein 0.0971 0.2786 0.8396
Schistosoma mansoni lamin 0.0058 0.0122 0.0282
Schistosoma mansoni microtubule-associated protein tau 0.1495 0.4316 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0044 0.008 0.008
Echinococcus granulosus Smad4 0.0028 0.0033 0.0047
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus multilocularis Smad4 0.0028 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0034 0.0053 0.0159
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0099 0.0243 0.0367
Leishmania major hypothetical protein, conserved 0.0319 0.0885 1
Loa Loa (eye worm) hypothetical protein 0.0306 0.0847 0.2553
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0081 0.0314
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0044 0.008 0.008
Schistosoma mansoni zinc finger protein 0.0026 0.0029 0.0067
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0117 0.0293 0.068
Schistosoma mansoni biogenic amine receptor 0.0044 0.008 0.0185
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0138 0.0355 0.0509
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.009 0.0349
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0343 0.0955 0.1479
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.008 0.0185
Echinococcus granulosus neuropeptide receptor 0.0044 0.008 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0055 0.0212
Loa Loa (eye worm) hypothetical protein 0.0296 0.0818 0.2465
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0074 0.0882
Trichomonas vaginalis D-aminoacylase, putative 0.0099 0.0243 0.0943
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0306 0.0847 0.1214
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.008 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0046 0.0177
Brugia malayi GnHR receptor homolog 0.0044 0.008 0.0241
Plasmodium falciparum zinc finger protein, putative 0.0019 0.0009 0.0033
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0052 0.0105 0.1184
Schistosoma mansoni bromodomain containing protein 0.0058 0.0122 0.0283
Echinococcus multilocularis ecdysone induced protein 78C 0.0306 0.0847 0.0847
Schistosoma mansoni nuclear receptor 0.0145 0.0375 0.0868
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0056 0.0117 0.1325
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Echinococcus granulosus nuclear receptor nhr 48 0.0145 0.0375 0.0537
Echinococcus granulosus histone acetyltransferase KAT2B 0.0128 0.0327 0.0468
Schistosoma mansoni hypothetical protein 0.0241 0.0655 0.1519
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0138 0.0355 0.0355
Entamoeba histolytica hypothetical protein 0.0096 0.0233 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0099 0.0243 0.0562
Echinococcus multilocularis dna polymerase kappa 0.0042 0.0074 0.0074
Brugia malayi mbt repeat family protein 0.0034 0.0053 0.0159
Schistosoma mansoni thyroid hormone receptor 0.0306 0.0847 0.1963
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus multilocularis L aminoadipate semialdehyde 0.0052 0.0106 0.0106
Leishmania major DNA polymerase eta, putative 0.0042 0.0074 0.0837
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0044 0.008 0.0185
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.2212 0.6411 1
Schistosoma mansoni hypothetical protein 0.0044 0.008 0.0185
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.008 0.0115
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0044 0.008 0.008
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0195 0.0521 0.2025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0041 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0042 0.0074 0.0223
Brugia malayi TAR-binding protein 0.0181 0.048 0.1446
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.001 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0056 0.0216
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0306 0.0847 0.1963
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0019 0.0007 0.031
Loa Loa (eye worm) nuclear hormone receptor 0.0145 0.0375 0.1129
Echinococcus multilocularis fmrfamide receptor 0.0044 0.008 0.008
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0393 0.11 0.3314
Schistosoma mansoni thyroid hormone receptor 0.0306 0.0847 0.1963
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Brugia malayi Serotonin receptor 0.0044 0.008 0.0241
Onchocerca volvulus 0.0145 0.0375 0.1455
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0028 0.0033 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0306 0.0847 0.2553
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0044 0.008 0.0185
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.008 0.008
Schistosoma mansoni amine GPCR 0.0044 0.008 0.0185
Brugia malayi follicle stimulating hormone receptor 0.0393 0.11 0.3314
Brugia malayi G protein-coupled receptor 0.0044 0.008 0.0241
Echinococcus granulosus 7tm_1 domain containing protein 0.0044 0.008 0.0115
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0044 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0034 0.005 0.0117
Brugia malayi MH1 domain containing protein 0.0028 0.0033 0.01
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0021 0.0015 0.0057
Brugia malayi G-protein coupled receptor 0.0044 0.008 0.0241
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0052 0.0203
Brugia malayi larval opioid receptor 0.0044 0.008 0.0241
Trypanosoma brucei importin beta-1 subunit, putative 0.0018 0.0006 0.0073
Echinococcus multilocularis thyroid hormone receptor alpha 0.0306 0.0847 0.0847
Plasmodium falciparum glutathione reductase 0.0052 0.0105 0.0407
Onchocerca volvulus 0.0044 0.008 0.0311
Brugia malayi Importin beta-1 subunit 0.0018 0.0006 0.0019
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0898 0.2574 1
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0019 0.0007 0.001
Toxoplasma gondii cathepsin CPC1 0.0077 0.0178 0.0691
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0343 0.0955 0.1479
Schistosoma mansoni hypothetical protein 0.1199 0.3454 0.8001
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0044 0.008 0.0241
Echinococcus multilocularis somatostatin receptor 0.0044 0.008 0.008
Schistosoma mansoni steroid hormone receptor ad4bp 0.0306 0.0847 0.1963
Echinococcus multilocularis SWI:SNF matrix associated 0.0898 0.2574 0.2574
Onchocerca volvulus 0.0044 0.008 0.0311
Brugia malayi HSF-type DNA-binding domain containing protein 0.0065 0.0142 0.0426
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.008 0.0115
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0033 0.0375
Echinococcus multilocularis G protein coupled receptor 139 0.0044 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0306 0.0847 0.2553
Echinococcus multilocularis smad 0.0028 0.0033 0.0033
Onchocerca volvulus 0.0195 0.0521 0.2025
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0898 0.2574 1
Echinococcus multilocularis protein dispatched 1 0.004 0.007 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.008 0.008
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Loa Loa (eye worm) hypothetical protein 0.0162 0.0425 0.1281
Plasmodium vivax SET domain protein, putative 0.0104 0.0257 0.0998
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.005 0.005
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.007 0.0158 0.071
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0036 0.0312
Loa Loa (eye worm) hypothetical protein 0.0195 0.0521 0.1571
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0145 0.0375 0.0375
Onchocerca volvulus 0.0044 0.008 0.0311
Echinococcus granulosus SWI:SNF matrix associated 0.0898 0.2574 0.3688
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0006 0.0024
Giardia lamblia Kinesin-5 0.0062 0.0134 0.754
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0059 0.0125 0.0179
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0062 0.024
Echinococcus granulosus ring finger protein 113a 0.0016 0 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0038 0.0064 0.0194
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0036 0.0107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0248 0.0676 0.1565
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0086 0.0203 0.047
Schistosoma mansoni hypothetical protein 0.0319 0.0885 0.2051
Toxoplasma gondii preprocathepsin c precursor, putative 0.0077 0.0178 0.0691
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0052 0.0105 0.1339
Echinococcus granulosus fmrfamide receptor 0.0044 0.008 0.0115
Echinococcus granulosus dnaJ subfamily B 0.136 0.3924 0.5621
Loa Loa (eye worm) hypothetical protein 0.019 0.0508 0.153
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0052 0.0105 0.0407
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0306 0.0847 0.2553
Loa Loa (eye worm) hypothetical protein 0.0137 0.0353 0.1064
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0252 0.0689 0.3218
Brugia malayi Dopamine receptor 0.0044 0.008 0.0241
Schistosoma mansoni RAR-like nuclear receptor 0.0306 0.0847 0.1963
Loa Loa (eye worm) hypothetical protein 0.0306 0.0847 0.2553
Echinococcus multilocularis g-protein coupled receptor 0.0044 0.008 0.008
Loa Loa (eye worm) acetyltransferase 0.0134 0.0342 0.1032
Loa Loa (eye worm) brahma associated protein 0.0898 0.2574 0.7757
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0898 0.2574 1
Giardia lamblia Protein 21.1 0.0016 0.000000012346 0.00000069359
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0044 0.008 0.008
Brugia malayi SWIB/MDM2 domain containing protein 0.0898 0.2574 0.7757
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.008 0.0185
Trichomonas vaginalis penicillin-binding protein, putative 0.0099 0.0243 0.0943
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0151 0.0392 0.06
Schistosoma mansoni lamin 0.0058 0.0122 0.0282
Brugia malayi T-complex protein 1, beta subunit 0.0019 0.0007 0.0022
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0021 0.0015 0.0624
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0306 0.0847 0.2553
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.008 0.0185
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0837
Schistosoma mansoni nuclear hormone receptor 0.0145 0.0375 0.0868
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0137 0.0353 0.0353
Echinococcus granulosus histone acetyltransferase MYST2 0.0039 0.0067 0.0095
Loa Loa (eye worm) hypothetical protein 0.019 0.0508 0.153
Onchocerca volvulus 0.0044 0.008 0.0311
Loa Loa (eye worm) hypothetical protein 0.0195 0.0521 0.1571
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0125 0.0486
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.0033 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0052 0.0203
Brugia malayi Disintegrin family protein 0.0018 0.0005 0.0016
Echinococcus granulosus peptide allatostatin:somatostatin 0.0044 0.008 0.0115
Schistosoma mansoni DNA polymerase eta 0.0042 0.0074 0.0172
Loa Loa (eye worm) Smad1 0.0028 0.0033 0.01
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0021 0.0015 0.0164
Trichomonas vaginalis ankyrin, putative 0.0016 0.000000012346 0.000000047957
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0114 0.0285 0.0409
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0052 0.0105 0.1184
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0252 0.0689 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0046 0.0177
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0319 0.0885 0.0885
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0319 0.0885 0.0885
Schistosoma mansoni SET domain protein 0.0017 0.0002 0.0005
Brugia malayi Carboxylesterase family protein 0.0195 0.0521 0.1571
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0044 0.008 0.0115
Echinococcus multilocularis serotonin receptor 0.0044 0.008 0.008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0306 0.0847 0.1963
Brugia malayi CXXC zinc finger family protein 0.0151 0.0393 0.1183
Schistosoma mansoni hypothetical protein 0.0898 0.2574 0.5964
Schistosoma mansoni myst-related protein 0.0019 0.0009 0.002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0324 0.0897 0.2078
Trichomonas vaginalis D-aminoacylase, putative 0.0099 0.0243 0.0943
Echinococcus granulosus TGF beta signal transducer SmadC 0.0028 0.0033 0.0047
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0074 0.0837
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.008 0.008
Onchocerca volvulus 0.0044 0.008 0.0311
Loa Loa (eye worm) hypothetical protein 0.0162 0.0425 0.1281
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0104
Onchocerca volvulus Protein ultraspiracle homolog 0.0306 0.0847 0.3291
Brugia malayi PHD-finger family protein 0.003 0.004 0.0121
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0036 0.0402
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Echinococcus multilocularis neuropeptide FF receptor 2 0.0044 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0044 0.008 0.0241
Trypanosoma cruzi DNA repair protein, putative 0.0022 0.0016 0.0179
Loa Loa (eye worm) hypothetical protein 0.0145 0.0375 0.1129
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.008 0.0115
Brugia malayi hypothetical protein 0.0145 0.0375 0.1129
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0201

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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