Detailed information for compound 691054

Basic information

Technical information
  • TDR Targets ID: 691054
  • Name: N-(3-methylphenyl)-2-[1-(2-methylphenyl)-4-ox opyrazolo[5,4-d]pyrimidin-5-yl]acetamide
  • MW: 373.408 | Formula: C21H19N5O2
  • H donors: 1 H acceptors: 3 LogP: 2.82 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1)NC(=O)Cn1cnc2c(c1=O)cnn2c1ccccc1C
  • InChi: 1S/C21H19N5O2/c1-14-6-5-8-16(10-14)24-19(27)12-25-13-22-20-17(21(25)28)11-23-26(20)18-9-4-3-7-15(18)2/h3-11,13H,12H2,1-2H3,(H,24,27)
  • InChiKey: FCGAWYPWFPEISC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-methylphenyl)-2-[1-(2-methylphenyl)-4-oxo-pyrazolo[5,4-d]pyrimidin-5-yl]acetamide
  • N-(3-methylphenyl)-2-[1-(2-methylphenyl)-4-oxo-5-pyrazolo[5,4-d]pyrimidinyl]acetamide
  • 2-[4-keto-1-(2-methylphenyl)pyrazolo[5,4-d]pyrimidin-5-yl]-N-(3-methylphenyl)acetamide
  • N-(3-methylphenyl)-2-[1-(2-methylphenyl)-4-oxo-pyrazolo[5,4-d]pyrimidin-5-yl]ethanamide
  • ZINC04479011

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0027 0.0084 0.0119
Echinococcus granulosus peptide allatostatin:somatostatin 0.0157 0.0915 0.0908
Plasmodium vivax SET domain protein, putative 0.0102 0.0564 0.096
Trypanosoma cruzi cruzipain precursor, putative 0.1193 0.754 0.754
Schistosoma mansoni protein phosphatase 2C 0.0036 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0027 0.0084 0.0081
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0157 0.0915 0.0915
Toxoplasma gondii cathepsin CPC1 0.0207 0.1232 0.2098
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0045 0.0539
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0062 0.0307 0.0307
Loa Loa (eye worm) hhat protein 0.0016 0.0016 0.0012
Echinococcus granulosus cathepsin L cysteine protease 0.0501 0.3114 0.3109
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0035 0.0133 0.0133
Echinococcus multilocularis glutamate receptor NMDA 0.005 0.023 0.0223
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.003 0.0105 0.0097
Onchocerca volvulus 0.0157 0.0915 0.1538
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.005 0.0231 0.0223
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0145 0.0841 0.0838
Echinococcus granulosus cathepsin l1 0.0932 0.5874 0.5871
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0207 0.1232 0.2098
Mycobacterium tuberculosis Probable lipase LipE 0.0145 0.0841 0.1408
Echinococcus granulosus g protein coupled receptor 0.0157 0.0915 0.0908
Echinococcus granulosus serotonin receptor 0.0157 0.0915 0.0908
Echinococcus granulosus transcription factor Dp 1 0.002 0.0039 0.0032
Echinococcus multilocularis glutamate receptor 2 0.0033 0.012 0.0112
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0064 0.0082
Echinococcus multilocularis cathepsin L cysteine protease 0.0932 0.5874 0.5871
Plasmodium falciparum cysteine proteinase falcipain 3 0.0932 0.5874 1
Schistosoma mansoni glutamate receptor NMDA 0.006 0.0297 0.0297
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0162 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0097 0.0531 0.0523
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0062 0.0307 0.3647
Echinococcus granulosus lipoxygenase domain containing protein 0.0016 0.0014 0.0006
Echinococcus granulosus neuropeptide s receptor 0.0157 0.0915 0.0908
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0157 0.0915 0.0915
Trichomonas vaginalis ap endonuclease, putative 0.005 0.0231 0.0367
Brugia malayi beta-lactamase 0.0145 0.0841 0.0838
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0062 0.0307 0.3285
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Loa Loa (eye worm) hypothetical protein 0.0638 0.3992 0.399
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0109 0.0109
Leishmania major cathepsin L-like protease 0.1193 0.754 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0016 0.0016 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0084 0.0111
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0207 0.1232 0.1232
Schistosoma mansoni hypothetical protein 0.0555 0.346 0.346
Trichomonas vaginalis conserved hypothetical protein 0.0207 0.1232 0.2076
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0162 0.0245
Brugia malayi Cytochrome P450 family protein 0.0021 0.0045 0.0042
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0045 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.1232 0.2076
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni biogenic amine (5HT) receptor 0.0157 0.0915 0.0915
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0062 0.0307 0.0307
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0207 0.1232 0.1232
Echinococcus granulosus cathepsin L 0.0501 0.3114 0.3109
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0062 0.0307 0.0407
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Echinococcus multilocularis neuropeptide Y receptor 0.0157 0.0915 0.0908
Echinococcus granulosus neuropeptide Y receptor 0.0157 0.0915 0.0908
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0016 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0075 0.0391 0.0388
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0062 0.0307 0.3647
Echinococcus granulosus cathepsin l1 0.0638 0.3992 0.3987
Schistosoma mansoni glutamate receptor kainate 0.0025 0.0073 0.0073
Plasmodium vivax importin-beta 2, putative 0.0015 0.0008 0.0013
Loa Loa (eye worm) glutamate receptor 0.0031 0.0106 0.0102
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0022 0.0051 0.0611
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0109 0.0102
Loa Loa (eye worm) hypothetical protein 0.003 0.0105 0.0101
Brugia malayi G protein-coupled receptor 0.0157 0.0915 0.0912
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0064 0.0082
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0067 0.0064
Entamoeba histolytica cysteine proteinase, putative 0.0501 0.3114 0.5289
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0022 0.0051 0.0611
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Leishmania major cytochrome p450-like protein 0.0073 0.0379 0.0503
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0157 0.0915 0.0915
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0157 0.0915 0.0912
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0564 0.0564
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0157 0.0915 0.0915
Giardia lamblia Cathepsin L-like protease 0.0207 0.1232 0.2968
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.081 0.0803
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0051 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Echinococcus multilocularis jumonji domain containing 1A 0.0036 0.0139 0.0131
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0062 0.0307 0.0493
Echinococcus multilocularis neuropeptide FF receptor 2 0.0157 0.0915 0.0908
Brugia malayi Dopamine receptor 0.0157 0.0915 0.0912
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0102 0.0564 0.0557
Mycobacterium tuberculosis Conserved protein 0.0145 0.0841 0.1408
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0022 0.0051 0.1069
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0025 0.0043
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0012
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0932 0.5874 0.5873
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0096 0.0524 0.0521
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0157 0.0915 0.0908
Schistosoma mansoni neuropeptide f receptor 76f 0.0157 0.0915 0.0915
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0294 0.1792 0.179
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0139 0.0136
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0207 0.1232 0.2098
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0109 0.0102
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi isocitrate dehydrogenase 0.0031 0.0109 0.0106
Schistosoma mansoni sterol O-acyltransferase 1 0.0169 0.0988 0.0988
Schistosoma mansoni neuropeptide receptor 0.0157 0.0915 0.0915
Onchocerca volvulus Cathepsin L homolog 0.0932 0.5874 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0157 0.0915 0.0915
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0157 0.0915 0.0915
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Brugia malayi Cathepsin L-like precursor 0.0294 0.1792 0.179
Brugia malayi Tachykinin-like peptides receptor 99D 0.0157 0.0915 0.0912
Trichomonas vaginalis set domain proteins, putative 0.0807 0.507 0.8628
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Schistosoma mansoni hypothetical protein 0.0555 0.346 0.346
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0294 0.1792 0.179
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0067 0.0067
Trypanosoma cruzi cruzipain precursor, putative 0.0294 0.1792 0.1792
Loa Loa (eye worm) MBOAT family protein 0.0016 0.0016 0.0012
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0035 0.0133 0.013
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi RNA, U transporter 1 0.0043 0.0187 0.0184
Onchocerca volvulus 0.0027 0.0084 0.0119
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0084 0.0081
Echinococcus granulosus tachykinin peptides receptor 99D 0.0157 0.0915 0.0908
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0064 0.0061
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0162 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0501 0.3114 0.413
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0109 0.0106
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0932 0.5874 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0207 0.1232 0.2076
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0084 0.0111
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0064 0.0077
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0033 0.012 0.0112
Echinococcus multilocularis beta LACTamase domain containing family member 0.0145 0.0841 0.0834
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0016 0.0016 0.0008
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0207 0.1232 0.2098
Onchocerca volvulus 0.0932 0.5874 1
Brugia malayi cathepsin L-like cysteine proteinase 0.0207 0.1232 0.1229
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.005 0.0231 0.037
Schistosoma mansoni hypothetical protein 0.003 0.0105 0.0105
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0045 0.0045
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni lipoxygenase 0.0068 0.0344 0.0344
Plasmodium falciparum serine repeat antigen 6 0.0207 0.1232 0.2098
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0067 0.006
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0022 0.0051 0.0611
Echinococcus granulosus lamin dm0 0.0027 0.0084 0.0076
Schistosoma mansoni glutamate receptor kainate 0.0025 0.0073 0.0073
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0109 0.0186
Onchocerca volvulus 0.0099 0.0545 0.0906
Onchocerca volvulus 0.0157 0.0915 0.1538
Echinococcus granulosus cathepsin l cysteine peptidase 0.0932 0.5874 0.5871
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.003 0.0105 0.0097
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0064 0.0061
Schistosoma mansoni cathepsin s 0.0294 0.1792 0.1792
Echinococcus multilocularis cysteine protease 0.0932 0.5874 0.5871
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0169 0.0988 0.0985
Schistosoma mansoni cpg binding protein 0.0027 0.0081 0.0081
Echinococcus granulosus G protein coupled receptor 139 0.0157 0.0915 0.0908
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0109 0.0186
Leishmania major cytochrome p450-like protein 0.0021 0.0045 0.006
Brugia malayi Glutamate receptor 2 precursor 0.0025 0.0073 0.007
Schistosoma mansoni glutamate receptor kainate 0.0025 0.0073 0.0073
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0109 0.0106
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Brugia malayi cathepsin F-like cysteine proteinase 0.0294 0.1792 0.179
Schistosoma mansoni opsin-like receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0045 0.0042
Trypanosoma cruzi acetyl-CoA carboxylase 0.0101 0.0554 0.0554
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0501 0.3114 0.413
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.005 0.0231 0.0363
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.005 0.0231 0.2743
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0162 0.025
Onchocerca volvulus 0.0145 0.0841 0.1411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0501 0.3114 0.5289
Loa Loa (eye worm) glutamate receptor 2 0.0025 0.0073 0.007
Loa Loa (eye worm) hypothetical protein 0.0052 0.0244 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0045 0.0045
Loa Loa (eye worm) cysteine protease 0.0932 0.5874 0.5873
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0157 0.0915 0.0908
Leishmania major DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Brugia malayi putative neuropeptide receptor NPR1 0.0157 0.0915 0.0912
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0064 0.0077
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trypanosoma brucei importin beta-1 subunit, putative 0.0015 0.0008 0.001
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0501 0.3114 0.3114
Schistosoma mansoni neuropeptide F-like receptor 0.0157 0.0915 0.0915
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0023 0.0059 0.0056
Echinococcus granulosus hypothetical protein 0.0157 0.0915 0.0908
Brugia malayi Dopamine receptor protein 1 0.0157 0.0915 0.0912
Schistosoma mansoni hypothetical protein 0.0157 0.0915 0.0915
Brugia malayi jmjC domain containing protein 0.0036 0.0139 0.0136
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0035 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0012
Brugia malayi MH2 domain containing protein 0.0025 0.0067 0.0064
Onchocerca volvulus 0.0157 0.0915 0.1538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Entamoeba histolytica cysteine protease, putative 0.0932 0.5874 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.1232 0.2076
Loa Loa (eye worm) hypothetical protein 0.0294 0.1792 0.179
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0045 0.0539
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.0157 0.0914 0.0911
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0022 0.0051 0.0044
Trypanosoma brucei cytochrome P450, putative 0.0073 0.0379 0.0503
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0016 0.0016 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0841 0.1408
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0064 0.0235
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0932 0.5874 1
Brugia malayi Cytochrome P450 family protein 0.0021 0.0045 0.0042
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0207 0.1232 0.1229
Mycobacterium leprae Probable lipase LipE 0.0145 0.0841 1
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Loa Loa (eye worm) MBOAT family protein 0.0016 0.0016 0.0012
Toxoplasma gondii cathepsin CPC2 0.0207 0.1232 0.2098
Echinococcus granulosus lysine specific demethylase 5A 0.0136 0.0778 0.0771
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0631 0.3944 0.6705
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trypanosoma cruzi glycerol uptake protein, putative 0.0016 0.0016 0.0016
Onchocerca volvulus 0.0157 0.0915 0.1538
Trypanosoma cruzi cytochrome P450, putative 0.0073 0.0379 0.0379
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0025 0.03
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0139 0.0136
Echinococcus granulosus dna polymerase kappa 0.0039 0.0162 0.0154
Brugia malayi diacylglycerol acyltransferase 0.0016 0.0016 0.0012
Loa Loa (eye worm) hhat protein 0.0016 0.0016 0.0012
Echinococcus granulosus cysteine protease 0.0501 0.3114 0.3109
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Leishmania major hypothetical protein, conserved 0.0036 0.0139 0.0185
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Leishmania major cysteine peptidase A (CPA) 0.0932 0.5874 0.779
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.003 0.0105 0.0097
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0207 0.1232 0.2968
Echinococcus multilocularis cathepsin b 0.1577 1 1
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Schistosoma mansoni polycystin 1-related 0.0016 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni alpha-1 adrenergic receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0061
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0932 0.5874 0.5873
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0932 0.5874 0.5871
Plasmodium vivax vivapain-2 0.0932 0.5874 1
Trypanosoma cruzi glycerol uptake protein, putative 0.0016 0.0016 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Brugia malayi Papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0207 0.1232 0.2098
Leishmania major cathepsin L-like protease 0.1193 0.754 1
Loa Loa (eye worm) G-protein coupled receptor 0.0157 0.0915 0.0912
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0109 0.0145
Loa Loa (eye worm) hypothetical protein 0.0066 0.033 0.0327
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0841 0.0841
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0157 0.0915 0.1538
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.003 0.0105 0.0097
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0022 0.0051 0.0051
Loa Loa (eye worm) cathepsin B 0.0631 0.3944 0.3942
Giardia lamblia Hypothetical protein 0.0207 0.1232 0.2968
Echinococcus granulosus o acyltransferase membrane bound domain 0.0016 0.0016 0.0008
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0026 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0061
Echinococcus multilocularis somatostatin receptor 0.0157 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Brugia malayi hypothetical protein 0.0016 0.0014 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0033 0.012 0.0112
Trichomonas vaginalis glucosylceramidase, putative 0.0227 0.1359 0.2294
Loa Loa (eye worm) transcription factor SMAD2 0.036 0.2214 0.2211
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0157 0.0915 0.0915
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni hypothetical protein 0.0016 0.0016 0.0016
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0062 0.0309 0.0309
Entamoeba histolytica cysteine proteinase, putative 0.0501 0.3114 0.5289
Echinococcus granulosus intermediate filament protein 0.0027 0.0084 0.0076
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0157 0.0915 0.0908
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.0841 0.1408
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Echinococcus multilocularis neuropeptide receptor 0.0157 0.0915 0.0908
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.0163 0.0951 0.1618
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0084 0.0081
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0035 0.0133 0.0133
Onchocerca volvulus 0.0932 0.5874 1
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0084 0.0081
Brugia malayi MH1 domain containing protein 0.0025 0.0067 0.0064
Echinococcus granulosus neuropeptides capa receptor 0.0157 0.0915 0.0908
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0157 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus granulosus neuropeptides capa receptor 0.0157 0.0915 0.0908
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0162 0.0154
Loa Loa (eye worm) jmjC domain-containing protein 0.0136 0.0778 0.0775
Onchocerca volvulus Cathepsin L homolog 0.0207 0.1232 0.2079
Echinococcus multilocularis sex peptide receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0157 0.0915 0.0908
Loa Loa (eye worm) cytochrome P450 family protein 0.0073 0.0379 0.0376
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0045 0.0539
Echinococcus multilocularis g protein coupled receptor 0.0157 0.0915 0.0908
Brugia malayi neuropeptide F receptor 0.0157 0.0915 0.0912
Onchocerca volvulus 0.0932 0.5874 1
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0062 0.0307 0.0407
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0162 0.025
Echinococcus granulosus somatostatin receptor 0.0157 0.0915 0.0908
Schistosoma mansoni hypothetical protein 0.0157 0.0915 0.0915
Schistosoma mansoni acetyl-CoA carboxylase 0.0163 0.0951 0.0951
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0157 0.0915 0.0912
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0157 0.0915 0.0908
Onchocerca volvulus 0.0157 0.0915 0.1538
Echinococcus granulosus lamin 0.0027 0.0084 0.0076
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0328 0.2006 0.2003
Plasmodium vivax hypothetical protein, conserved 0.0145 0.0841 0.1431
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0157 0.0915 0.0908
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0062 0.0307 0.0493
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0035 0.0133 0.0177
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Entamoeba histolytica cysteine proteinase 1, putative 0.0501 0.3114 0.5289
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0207 0.1232 0.1229
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.081 0.0803
Trypanosoma brucei unspecified product 0.0039 0.0162 0.0215
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0161 0.0941 0.0941
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.005 0.0231 0.0306
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0162 0.0154
Echinococcus granulosus g-protein coupled receptor 0.0157 0.0915 0.0908
Onchocerca volvulus 0.0027 0.0081 0.0115
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0841 0.0841
Mycobacterium tuberculosis Probable lipase LipD 0.0145 0.0841 0.1408
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0061
Brugia malayi Papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0849 0.0842
Trypanosoma cruzi cysteine proteinase, putative 0.0501 0.3114 0.3114
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0064 0.0085
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Trichomonas vaginalis ap endonuclease, putative 0.005 0.0231 0.0367
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0187 0.0179
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1577 1 1
Schistosoma mansoni biogenic amine receptor 0.0157 0.0915 0.0915
Brugia malayi RNA recognition motif domain containing protein 0.0096 0.0524 0.0521
Trypanosoma brucei unspecified product 0.0041 0.0171 0.0227
Onchocerca volvulus 0.0055 0.0265 0.0428
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0062 0.0307 0.0407
Trypanosoma cruzi GUP1, putative 0.0016 0.0016 0.0016
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0016 0.0016 0.0016
Brugia malayi Smad1 0.0025 0.0067 0.0064
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0207 0.1232 0.2098
Plasmodium falciparum LCCL domain-containing protein 0.0016 0.0014 0.0024
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0929 0.5854 1
Brugia malayi Serotonin receptor 0.0157 0.0915 0.0912
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.005 0.0231 0.0231
Echinococcus multilocularis lamin dm0 0.0027 0.0084 0.0076
Echinococcus multilocularis cysteine protease 0.0932 0.5874 0.5871
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0157 0.0915 0.0912
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Loa Loa (eye worm) MH2 domain-containing protein 0.036 0.2214 0.2211
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0062 0.0307 0.0307
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0157 0.0915 0.0908
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0062 0.0307 0.0307
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0501 0.3114 0.3114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0638 0.3992 0.6788
Mycobacterium ulcerans hypothetical protein 0.0145 0.0841 1
Echinococcus granulosus neuropeptide receptor A26 0.0157 0.0915 0.0908
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.081 0.081
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0157 0.0915 0.0912
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.0545 0.0545
Onchocerca volvulus 0.0157 0.0915 0.1538
Echinococcus multilocularis neuropeptide Y receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis GPCR, family 2 0.003 0.0105 0.0097
Entamoeba histolytica cysteine proteinase, putative 0.0501 0.3114 0.5289
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0501 0.3114 0.3114
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0029 0.0097 0.0097
Echinococcus granulosus alpha 1A adrenergic receptor 0.0157 0.0915 0.0908
Schistosoma mansoni hypothetical protein 0.0157 0.0915 0.0915
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0157 0.0915 0.0912
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0109 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Trypanosoma cruzi cysteine peptidase, putative 0.0294 0.1792 0.1792
Toxoplasma gondii preprocathepsin c precursor, putative 0.0207 0.1232 0.2098
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0564 0.0564
Brugia malayi Hhat protein 0.0016 0.0016 0.0012
Echinococcus granulosus o acyltransferase membrane bound domain 0.0016 0.0016 0.0008
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0187 0.0318
Echinococcus granulosus tm gpcr rhodopsin 0.0157 0.0915 0.0908
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0064 0.0762
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Echinococcus granulosus geminin 0.0555 0.346 0.3455
Giardia lamblia Cathepsin B precursor 0.0631 0.3944 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0157 0.0915 0.0908
Schistosoma mansoni histamine h1 receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) ctsf protein 0.0932 0.5874 0.5873
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0207 0.1232 0.2098
Trypanosoma brucei cysteine peptidase C (CPC) 0.0631 0.3944 0.523
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Echinococcus multilocularis g protein coupled receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis tumor protein p63 0.0678 0.4247 0.4243
Schistosoma mansoni ap endonuclease 0.005 0.0231 0.0231
Schistosoma mansoni hypothetical protein 0.0163 0.095 0.095
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0062 0.0307 0.3647
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0045 0.0539
Brugia malayi hypothetical protein 0.0016 0.0014 0.0011
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0033 0.012 0.0112
Schistosoma mansoni biogenic amine receptor 0.0157 0.0915 0.0915
Echinococcus multilocularis sterol O acyltransferase 1 0.0169 0.0988 0.0981
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0157 0.0915 0.0912
Leishmania major DNA polymerase eta, putative 0.0039 0.0162 0.0215
Schistosoma mansoni ap endonuclease 0.005 0.0231 0.0231
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0016 0.0016 0.0008
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni opsin-like receptor 0.0157 0.0915 0.0915
Schistosoma mansoni smad1 5 8 and 0.0025 0.0067 0.0067
Loa Loa (eye worm) N-myristoyltransferase 2 0.011 0.0614 0.0611
Echinococcus multilocularis JmjC domain containing protein 4 0.0036 0.0139 0.0131
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Onchocerca volvulus 0.0157 0.0915 0.1538
Echinococcus granulosus Polycystic kidney disease protein 0.0016 0.0014 0.0006
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0139 0.0139
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0045 0.0539
Plasmodium vivax unspecified product 0.0501 0.3114 0.5301
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0281 0.0478
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0162 0.0215
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0162 0.0162
Brugia malayi Latrophilin receptor protein 2 0.003 0.0105 0.0101
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0162 0.1927
Mycobacterium ulcerans pyruvate carboxylase 0.0062 0.0307 0.3647
Schistosoma mansoni rab6-interacting 0.0016 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0102 0.0564 0.0561
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0035 0.0133 0.013
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Echinococcus granulosus cathepsin L 0.0207 0.1232 0.1225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Onchocerca volvulus 0.0145 0.0841 0.1411
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Brugia malayi RE15519p 0.0157 0.0915 0.0912
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0022 0.0051 0.0611
Echinococcus granulosus Smad4 0.0025 0.0067 0.006
Schistosoma mansoni hypothetical protein 0.003 0.0105 0.0105
Trichomonas vaginalis N-myristoyl transferase, putative 0.0072 0.0373 0.0609
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0207 0.1232 0.2076
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0102
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Echinococcus multilocularis snurportin 1 0.0163 0.095 0.0943
Giardia lamblia Cathepsin L-like protease 0.0207 0.1232 0.2968
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Echinococcus granulosus metabotropic glutamate receptor 5 0.0036 0.0144 0.0136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Plasmodium vivax multidomain scavenger receptor, putative 0.0016 0.0014 0.0024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0297 0.0297
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0157 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0022 0.0051 0.0056
Onchocerca volvulus 0.0932 0.5874 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.081 0.0803
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Schistosoma mansoni cathepsin B (C01 family) 0.0207 0.1232 0.1232
Trypanosoma brucei N-myristoyl transferase, putative 0.011 0.0614 0.0814
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0016 0.0016 0.0008
Schistosoma mansoni smad1 5 8 and 0.0025 0.0067 0.0067
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0102
Plasmodium falciparum serine repeat antigen 1 0.0207 0.1232 0.2098
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0932 0.5874 0.5871
Entamoeba histolytica cysteine proteinase 2 0.0501 0.3114 0.5289
Echinococcus granulosus neuropeptide receptor 0.0157 0.0915 0.0908
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0899 0.5659 0.5659
Echinococcus granulosus cpg binding protein 0.0028 0.0091 0.0083
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0187 0.0318
Echinococcus granulosus GPCR family 2 0.003 0.0105 0.0097
Plasmodium vivax unspecified product 0.0207 0.1232 0.2098
Trypanosoma cruzi N-myristoyl transferase, putative 0.011 0.0614 0.0614
Schistosoma mansoni biogenic amine receptor 0.0157 0.0915 0.0915
Plasmodium falciparum serine repeat antigen 7 0.0207 0.1232 0.2098
Onchocerca volvulus 0.0638 0.3992 0.6789
Leishmania major N-myristoyl transferase, putative 0.011 0.0614 0.0814
Giardia lamblia Cathepsin B precursor 0.0631 0.3944 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.0841 0.1408
Plasmodium falciparum JmjC domain-containing protein, putative 0.0036 0.0139 0.0237
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0134 0.0768 0.0761
Echinococcus granulosus dna polymerase eta 0.0039 0.0162 0.0154
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0035 0.0133 0.0177
Plasmodium falciparum serine repeat antigen 4 0.0207 0.1232 0.2098
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0045 0.0539
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0036 0.0139 0.0139
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1577 1 1
Echinococcus granulosus sterol O acyltransferase 1 0.0169 0.0988 0.0981
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Echinococcus multilocularis geminin 0.0555 0.346 0.3455
Schistosoma mansoni lipoxygenase 0.0097 0.0531 0.0531
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Schistosoma mansoni growth hormone secretagogue receptor 0.0157 0.0915 0.0915
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0207 0.1232 0.2098
Toxoplasma gondii HEAT repeat-containing protein 0.0015 0.0008 0.0013
Onchocerca volvulus 0.0157 0.0915 0.1538
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0118 0.0663 0.1129
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trypanosoma cruzi cysteine proteinase, putative 0.0501 0.3114 0.3114
Schistosoma mansoni hypothetical protein 0.0021 0.0045 0.0045
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0045 0.0045
Loa Loa (eye worm) beta-lactamase 0.0145 0.0841 0.0838
Echinococcus multilocularis nmda type glutamate receptor 0.0057 0.0277 0.0269
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0033 0.012 0.0112
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0035 0.0133 0.0126
Plasmodium falciparum serine repeat antigen 2 0.0207 0.1232 0.2098
Trypanosoma cruzi cysteine peptidase, putative 0.1193 0.754 0.754
Echinococcus granulosus lipoxygenase domain containing protein 0.0016 0.0014 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0045 0.0045
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus multilocularis phd:f box containing protein 0.0036 0.0139 0.0131
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis lysine specific demethylase 6a 0.0036 0.0139 0.0131
Echinococcus granulosus fmrfamide receptor 0.0157 0.0915 0.0908
Brugia malayi cathepsin Z-like cysteine proteinase 0.0207 0.1232 0.1229
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0162 0.0215
Loa Loa (eye worm) CXXC zinc finger family protein 0.0027 0.0081 0.0078
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0037 0.0149 0.0141
Plasmodium falciparum importin beta, putative 0.0015 0.0008 0.0013
Loa Loa (eye worm) glutamate receptor 1 0.0025 0.0073 0.007
Brugia malayi G protein-coupled receptor F59B2.13 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Giardia lamblia Cysteine protease 0.0207 0.1232 0.2968
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0109 0.0145
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0157 0.0915 0.0908
Brugia malayi cathepsin L-like precursor 0.0638 0.3992 0.399
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Echinococcus multilocularis lipoxygenase domain containing protein 0.0016 0.0014 0.0006
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0045 0.0539
Echinococcus multilocularis fmrfamide receptor 0.0157 0.0915 0.0908
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0501 0.3114 0.3114
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0011
Echinococcus granulosus tar DNA binding protein 0.0096 0.0524 0.0517
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi cathepsin L precursor 0.0207 0.1232 0.1229
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0016 0.0016 0.0008
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.005 0.0231 0.0223
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0037 0.0149 0.0141
Echinococcus granulosus neuropeptide FF receptor 2 0.0157 0.0915 0.0908
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0162 0.0154
Onchocerca volvulus 0.0016 0.0016 0.0003
Onchocerca volvulus 0.0207 0.1232 0.2079
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.005 0.0231 0.7521
Mycobacterium ulcerans lipase LipD 0.0145 0.0841 1
Trichomonas vaginalis esterase, putative 0.0145 0.0841 0.1408
Loa Loa (eye worm) hypothetical protein 0.1577 1 1
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Onchocerca volvulus 0.0157 0.0915 0.1538
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0102
Leishmania major acetyl-CoA carboxylase, putative 0.0163 0.0951 0.1261
Brugia malayi cathepsin Z-like cysteine proteinase 0.0207 0.1232 0.1229
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0207 0.1232 0.2098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0045 0.0539
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0045 0.0539
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0051 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0564 0.0564
Brugia malayi beta-lactamase family protein 0.0145 0.0841 0.0838
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1001 0.6314 0.6311
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0157 0.0915 0.0908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Mycobacterium tuberculosis Conserved protein 0.0145 0.0841 0.1408
Echinococcus multilocularis neuropeptides capa receptor 0.0157 0.0915 0.0908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Onchocerca volvulus 0.0157 0.0915 0.1538
Brugia malayi Carboxyl transferase domain containing protein 0.0157 0.0914 0.0911
Giardia lamblia Cysteine protease 0.0207 0.1232 0.2968
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Loa Loa (eye worm) hypothetical protein 0.0294 0.1792 0.179
Plasmodium vivax JmjC domain containing protein 0.0036 0.0139 0.0237
Loa Loa (eye worm) hypothetical protein 0.0638 0.3992 0.399
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0932 0.5874 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0067 0.006
Brugia malayi Melatonin receptor type 1A 0.0157 0.0915 0.0912
Echinococcus granulosus glutamate receptor 2 0.0033 0.012 0.0112
Loa Loa (eye worm) hypothetical protein 0.0039 0.0162 0.0159
Brugia malayi jmjC domain containing protein 0.0036 0.0139 0.0136
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Loa Loa (eye worm) hypothetical protein 0.0294 0.1792 0.179
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0162 0.0162
Schistosoma mansoni zinc finger protein 0.0016 0.0016 0.0016
Toxoplasma gondii cathepsin B 0.0631 0.3944 0.6714
Entamoeba histolytica exodeoxyribonuclease III, putative 0.005 0.0231 0.0367
Brugia malayi CXXC zinc finger family protein 0.0027 0.0081 0.0078
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0045 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Echinococcus granulosus glycylpeptide N tetradecanoyltransferase 0.011 0.0614 0.0607
Echinococcus multilocularis dna polymerase eta 0.0039 0.0162 0.0154
Plasmodium falciparum glycylpeptide N-tetradecanoyltransferase 0.011 0.0614 0.1045
Trypanosoma brucei unspecified product 0.0027 0.0084 0.0111
Plasmodium falciparum serine repeat antigen 5 0.0207 0.1232 0.2098
Entamoeba histolytica cysteine proteinase, putative 0.0638 0.3992 0.6788
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0045 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Echinococcus granulosus snurportin 1 0.0163 0.095 0.0943
Brugia malayi larval opioid receptor 0.0157 0.0915 0.0912
Loa Loa (eye worm) melatonin receptor type 1A 0.0157 0.0915 0.0912
Schistosoma mansoni ATP-binding cassette transporter 0.0025 0.0073 0.0073
Brugia malayi putative neuropeptide receptor 0.0157 0.0915 0.0912
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0016 0.0016 0.0016
Schistosoma mansoni Smad4 0.0025 0.0067 0.0067
Echinococcus multilocularis cpg binding protein 0.0028 0.0091 0.0083
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0012
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0025 0.0043
Schistosoma mansoni hypothetical protein 0.0157 0.0915 0.0915
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0118 0.0663 0.1129
Brugia malayi cytochrome P450 0.0021 0.0045 0.0042
Giardia lamblia Cysteine protease 0.0207 0.1232 0.2968
Echinococcus granulosus jumonji domain containing 1A 0.0036 0.0139 0.0131
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0162 0.0159
Entamoeba histolytica cysteine proteinase, putative 0.0932 0.5874 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0162 0.025
Leishmania major cytochrome p450-like protein 0.0021 0.0045 0.006
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0045 0.0045
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Schistosoma mansoni loxhd1 0.0016 0.0014 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0227 0.1359 0.2294
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.081 0.0807
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0157 0.0915 0.0915
Schistosoma mansoni importin beta-1 0.0015 0.0008 0.0008
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0134 0.0768 0.0761
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0164 0.0278
Trypanosoma cruzi glycerol uptake protein, putative 0.0016 0.0016 0.0016
Trichomonas vaginalis N-myristoyl transferase, putative 0.011 0.0614 0.1021
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0045 0.0045
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1577 1 1
Echinococcus multilocularis g protein coupled receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Mycobacterium ulcerans esterase/lipase LipP 0.0145 0.0841 1
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Brugia malayi Cathepsin L-like precursor 0.0638 0.3992 0.399
Trypanosoma cruzi major cysteine proteinase, putative 0.0467 0.2899 0.2899
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Echinococcus granulosus g protein coupled receptor 0.0157 0.0915 0.0908
Brugia malayi MH2 domain containing protein 0.036 0.2214 0.2211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Loa Loa (eye worm) fibroinase 0.0932 0.5874 0.5873
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.081 0.081
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0164 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0207 0.1232 0.2076
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0841 0.1408
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Loa Loa (eye worm) hypothetical protein 0.0036 0.0139 0.0136
Trypanosoma brucei hypothetical protein, conserved 0.0145 0.0841 0.1115
Loa Loa (eye worm) hypothetical protein 0.0932 0.5874 0.5873
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0036 0.0139 0.0237
Loa Loa (eye worm) hypothetical protein 0.0062 0.0309 0.0306
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0016 0.0016 0.0008
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0022 0.0051 0.0068
Schistosoma mansoni opsin-like receptor 0.0157 0.0915 0.0915
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0045 0.0539
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.1232 0.2076
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0073 0.0379 0.4511
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0084 0.0111
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0045 0.0038
Onchocerca volvulus Huntingtin homolog 0.0075 0.0391 0.0643
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0328 0.2006 0.2003
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Schistosoma mansoni biogenic amine (5HT) receptor 0.0157 0.0915 0.0915
Schistosoma mansoni neuropeptide receptor 0.0157 0.0915 0.0915
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Echinococcus multilocularis fmrfamide receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) RNA binding protein 0.0096 0.0524 0.0521
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0163 0.095 0.0947
Echinococcus granulosus RUN 0.0016 0.0014 0.0006
Toxoplasma gondii exonuclease III APE 0.005 0.0231 0.0393
Brugia malayi Cathepsin L-like cysteine proteinase 0.0638 0.3992 0.399
Loa Loa (eye worm) hypothetical protein 0.0075 0.0391 0.0388
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Loa Loa (eye worm) latrophilin receptor protein 2 0.003 0.0105 0.0101
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0109 0.0186
Echinococcus multilocularis lamin 0.0027 0.0084 0.0076
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.1193 0.754 0.754
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0045 0.0045
Echinococcus multilocularis musashi 0.0027 0.0084 0.0076
Schistosoma mansoni glutamate receptor AMPA 0.0025 0.0073 0.0073
Echinococcus multilocularis neuropeptides capa receptor 0.0157 0.0915 0.0908
Schistosoma mansoni cathepsin F (C01 family) 0.0932 0.5874 0.5874
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Plasmodium vivax vivapain-3 0.0501 0.3114 0.5301
Schistosoma mansoni cathepsin S (C01 family) 0.0207 0.1232 0.1232
Brugia malayi G-protein coupled receptor 0.0157 0.0915 0.0912
Brugia malayi Importin beta-1 subunit 0.0015 0.0008 0.0004
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) Smad1 0.0025 0.0067 0.0064
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0022 0.0051 0.0076
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0035 0.0133 0.0126
Plasmodium vivax vivapain-1 0.0501 0.3114 0.5301
Trypanosoma brucei glycerol uptake protein, putative 0.0016 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0207 0.1232 0.2076
Schistosoma mansoni hypothetical protein 0.0016 0.0014 0.0014
Schistosoma mansoni glutamate receptor NMDA 0.0083 0.044 0.044
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0059 0.0052
Brugia malayi GnHR receptor homolog 0.0157 0.0915 0.0912
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0162 0.0215
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0841 0.1408
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1577 1 1
Onchocerca volvulus Huntingtin homolog 0.0075 0.0391 0.0643
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0157 0.0915 0.0912
Brugia malayi Cytochrome P450 family protein 0.0073 0.0379 0.0376
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0016 0.0016 0.0027
Echinococcus multilocularis smad 0.0025 0.0067 0.006
Brugia malayi beta-lactamase family protein 0.0145 0.0841 0.0838
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0016 0.0016 0.0016
Toxoplasma gondii hypothetical protein 0.0016 0.0016 0.0027
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0823 0.0816
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0207 0.1232 0.2076
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0062 0.0307 0.0299
Schistosoma mansoni smad 0.0025 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Plasmodium falciparum serine repeat antigen 8 0.0207 0.1232 0.2098
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0187 0.0292
Loa Loa (eye worm) neuropeptide F receptor 0.0157 0.0915 0.0912
Giardia lamblia Hypothetical protein 0.0207 0.1232 0.2968
Echinococcus granulosus dro:myosuppressin receptor 0.0157 0.0915 0.0908
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0036 0.0139 0.0237
Mycobacterium tuberculosis Conserved protein 0.0145 0.0841 0.1408
Echinococcus multilocularis glutamate receptor 2 0.0025 0.0073 0.0066
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0139 0.0139
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0016 0.0016 0.0016
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0022 0.0051 0.0076
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0207 0.1232 0.2098
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni neuropeptide receptor 0.0157 0.0915 0.0915
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0638 0.3992 0.6788
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0016 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni intermediate filament proteins 0.0027 0.0084 0.0084
Brugia malayi jmjC domain containing protein 0.0134 0.0768 0.0765
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0033 0.012 0.0112
Trypanosoma cruzi GUP1, putative 0.0016 0.0016 0.0016
Loa Loa (eye worm) MBOAT family protein 0.0016 0.0016 0.0012
Brugia malayi N-myristoyltransferase 2 0.011 0.0614 0.0611
Schistosoma mansoni cpg binding protein 0.0028 0.0091 0.0091
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0016 0.0016 0.0027
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0096 0.0524 0.0521
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0011
Echinococcus granulosus tm gpcr rhodopsin 0.0157 0.0915 0.0908
Brugia malayi Glutamate receptor 1 precursor 0.0025 0.0073 0.007
Echinococcus multilocularis neuropeptide receptor 0.0157 0.0915 0.0908
Brugia malayi ORL1-like opioid receptor 0.0157 0.0915 0.0912
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.005 0.0231 0.0306
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Schistosoma mansoni hypothetical protein 0.003 0.0105 0.0105
Brugia malayi Pre-SET motif family protein 0.0102 0.0564 0.0561
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis serotonin receptor 0.0157 0.0915 0.0908
Echinococcus granulosus cathepsin L cysteine proteinase 0.0932 0.5874 0.5871
Schistosoma mansoni jumonji domain containing protein 0.0134 0.0768 0.0768
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0036 0.0139 0.0185
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.005 0.0231 0.0393
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0157 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Loa Loa (eye worm) cytochrome P450 0.0021 0.0045 0.0042
Brugia malayi Cathepsin L-like precursor 0.0638 0.3992 0.399
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0067 0.006
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0162 0.0245
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus granulosus biogenic amine 5HT receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis Polycystic kidney disease protein 0.0016 0.0014 0.0006
Brugia malayi metabotropic glutamate receptor type 2 0.0017 0.0021 0.0018
Echinococcus multilocularis neuropeptide receptor A26 0.0157 0.0915 0.0908
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0045 0.0045
Leishmania major hypothetical protein, conserved 0.0145 0.0841 0.1115
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0849 0.0846
Leishmania major hypothetical protein, conserved 0.0016 0.0016 0.0021
Echinococcus multilocularis nmda type glutamate receptor 0.0059 0.0291 0.0283
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0045 0.0077
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.005 0.0231 0.0393
Echinococcus granulosus 7tm_1 domain containing protein 0.0157 0.0915 0.0908
Echinococcus granulosus JmjC domain containing protein 4 0.0036 0.0139 0.0131
Loa Loa (eye worm) TAR-binding protein 0.0096 0.0524 0.0521
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0631 0.3944 0.3944
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0045 0.0539
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Brugia malayi MH1 domain containing protein 0.0025 0.0067 0.0064
Echinococcus multilocularis G protein coupled receptor 139 0.0157 0.0915 0.0908
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0045 0.0045
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Brugia malayi Trypsin family protein 0.0062 0.0309 0.0306
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus granulosus orexin receptor type 2 0.0157 0.0915 0.0908
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0045 0.0045
Trypanosoma cruzi cysteine peptidase, putative 0.0501 0.3114 0.3114
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0045 0.0045
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0045 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) G-protein coupled receptor 0.0157 0.0915 0.0912
Brugia malayi AKH receptor 0.0157 0.0915 0.0912
Brugia malayi jmjC domain containing protein 0.0036 0.0139 0.0136
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0139 0.0136
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0022 0.0051 0.0056
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0022 0.0051 0.0088
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0016 0.0016 0.0008
Plasmodium vivax vivapain-2 0.0932 0.5874 1
Echinococcus granulosus nmda type glutamate receptor 0.0059 0.0291 0.0283
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0932 0.5874 0.5871
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Schistosoma mansoni glutamate receptor AMPA 0.0025 0.0073 0.0073
Plasmodium falciparum serine repeat antigen 9 0.0207 0.1232 0.2098
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0045 0.0539
Schistosoma mansoni hypothetical protein 0.0066 0.033 0.033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.081 0.081
Echinococcus granulosus 7TM GPCR rhodopsin 0.0157 0.0915 0.0908
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0064 0.0762
Giardia lamblia CDC72 0.011 0.0614 0.1364
Brugia malayi Serotonin receptor 0.0157 0.0915 0.0912
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0162 0.0162
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0102 0.0564 0.0557
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni rab6-interacting 0.0016 0.0014 0.0014
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0187 0.0318
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0064 0.0085
Schistosoma mansoni pyruvate carboxylase 0.0062 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Loa Loa (eye worm) CYP4Cod1 0.0073 0.0379 0.0376
Brugia malayi Dopamine receptor protein 2 0.0157 0.0915 0.0912
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0631 0.3944 0.3944
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0016 0.0016 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Onchocerca volvulus Cathepsin F homolog 0.0932 0.5874 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0045 0.0045
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Onchocerca volvulus 0.0157 0.0915 0.1538
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0022 0.0051 0.1676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Brugia malayi Papain family cysteine protease containing protein 0.0501 0.3114 0.3112
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0157 0.0915 0.0912
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Loa Loa (eye worm) neuropeptide F receptor 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0045 0.0045
Onchocerca volvulus Cathepsin L homolog 0.0932 0.5874 1
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0162 0.0159
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Echinococcus multilocularis cathepsin b 0.1577 1 1
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi sulfakinin receptor protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0207 0.1232 0.2098
Brugia malayi Calcitonin receptor-like protein seb-1 0.0096 0.0524 0.0521
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0503 0.3127 0.3122
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0033 0.012 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Brugia malayi fibroinase precursor 0.0207 0.1232 0.1229
Echinococcus multilocularis RUN 0.0016 0.0014 0.0006
Leishmania major carboxylase, putative 0.0062 0.0307 0.0407
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0015 0.0008 0.001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0098 0.0536 0.0529
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Onchocerca volvulus 0.0932 0.5874 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0109 0.0186
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0157 0.0915 0.0908
Entamoeba histolytica cysteine proteinase, putative 0.0932 0.5874 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0045 0.0539
Echinococcus granulosus lysine specific demethylase 6a 0.0036 0.0139 0.0131
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Onchocerca volvulus 0.0157 0.0915 0.1538
Echinococcus multilocularis transcription factor Dp 1 0.002 0.0039 0.0032
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0062 0.0309 0.0309
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0016 0.0016 0.0008
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0207 0.1232 0.2098
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0045 0.0539
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.0163 0.0951 0.0943
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Brugia malayi Metabotropic glutamate receptor precursor. 0.0031 0.0106 0.0102
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0157 0.0915 0.0908
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Toxoplasma gondii ABC1 family protein 0.0145 0.0841 0.1431
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0045 0.0539
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0157 0.0915 0.0908
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0064 0.0235
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.0077
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0022 0.0051 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0207 0.1232 0.2076
Loa Loa (eye worm) doublecortin family protein 0.0016 0.0014 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0045 0.0045
Onchocerca volvulus 0.0157 0.0915 0.1538
Mycobacterium ulcerans beta-lactamase 0.0145 0.0841 1
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0109 0.0145
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus multilocularis lipoxygenase domain containing protein 0.0016 0.0014 0.0006
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0016 0.0016 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Echinococcus granulosus glutamate NMDA receptor subunit 0.006 0.0297 0.029
Trypanosoma brucei glycerol uptake protein, putative 0.0016 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0207 0.1232 0.1232
Echinococcus multilocularis g-protein coupled receptor 0.0157 0.0915 0.0908
Trypanosoma brucei N-myristoyltransferase 0.011 0.0614 0.0814
Echinococcus granulosus smad 0.0025 0.0067 0.006
Trypanosoma cruzi N-myristoyl transferase, putative 0.011 0.0614 0.0614
Loa Loa (eye worm) hypothetical protein 0.0096 0.0524 0.0521
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0064 0.0762
Echinococcus multilocularis allatostatin A receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis 0.0021 0.0045 0.0038
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0067 0.0064
Echinococcus multilocularis glycylpeptide N tetradecanoyltransferase 0.011 0.0614 0.0607
Echinococcus granulosus ankyrin repeat protein 0.0161 0.0941 0.0933
Toxoplasma gondii pyruvate carboxylase 0.0062 0.0307 0.0522
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0045 0.0539
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0145 0.0841 0.1408
Schistosoma mansoni adenoreceptor 0.0157 0.0915 0.0915
Onchocerca volvulus 0.0024 0.0064 0.0085
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0045 0.0539
Trypanosoma cruzi cysteine peptidase, putative 0.1193 0.754 0.754
Onchocerca volvulus 0.0932 0.5874 1
Brugia malayi Papain family cysteine protease containing protein 0.0932 0.5874 0.5873
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0157 0.0915 0.0908
Echinococcus granulosus glutamate receptor 2 0.0023 0.0059 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0045 0.0045
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0064 0.0085
Schistosoma mansoni cpg binding protein 0.0028 0.0091 0.0091
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.005 0.0231 0.0231
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0145 0.0841 0.0838
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0004
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0016 0.0016 0.0008
Plasmodium vivax glycylpeptide N-tetradecanoyltransferase, putative 0.011 0.0614 0.1045
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0709 0.4444 0.4442
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0207 0.1232 0.2968
Echinococcus granulosus sex peptide receptor 0.0157 0.0915 0.0908
Brugia malayi jmjC domain containing protein 0.0036 0.0139 0.0136
Trypanosoma cruzi cytochrome P450, putative 0.0073 0.0379 0.0379
Echinococcus multilocularis ankyrin repeat protein 0.0161 0.0941 0.0933
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0045 0.0045
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0045 0.0045
Entamoeba histolytica cysteine proteinase, putative 0.0501 0.3114 0.5289
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0207 0.1232 0.2076
Echinococcus multilocularis tar DNA binding protein 0.0096 0.0524 0.0517
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0162 0.1927
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis cathepsin L 0.0501 0.3114 0.3109
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Echinococcus granulosus g protein coupled receptor 0.0157 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.1232 0.2076
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0102 0.0564 0.096
Trypanosoma cruzi major cysteine proteinase, putative 0.0207 0.1232 0.1232
Loa Loa (eye worm) hypothetical protein 0.0036 0.0139 0.0136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0022 0.0051 0.0611
Entamoeba histolytica hypothetical protein 0.0207 0.1232 0.2076
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0162 0.0215
Brugia malayi TAR-binding protein 0.0096 0.0524 0.0521
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0145 0.0841 0.1408
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0109 0.0155
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Leishmania major cathepsin L-like protease 0.1193 0.754 1
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0016 0.0016 0.0008
Onchocerca volvulus Glucosylceramidase homolog 0.0215 0.1285 0.2169
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Onchocerca volvulus 0.0102 0.0564 0.0938
Echinococcus granulosus tm gpcr rhodopsin 0.0503 0.3127 0.3122
Loa Loa (eye worm) TYRA-2 protein 0.0157 0.0915 0.0912
Brugia malayi neuropeptide F receptor 0.0157 0.0915 0.0912
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Brugia malayi G-protein coupled receptor 0.0157 0.0915 0.0912
Schistosoma mansoni smad1 5 8 and 0.0025 0.0067 0.0067
Schistosoma mansoni jumonji/arid domain-containing protein 0.0136 0.0778 0.0778
Echinococcus multilocularis neuropeptide s receptor 0.0157 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Onchocerca volvulus 0.0157 0.0915 0.1538
Loa Loa (eye worm) acetyltransferase 0.0147 0.0849 0.0846
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0016 0.0016 0.0027
Loa Loa (eye worm) hypothetical protein 0.0062 0.0309 0.0306
Brugia malayi RNA binding protein 0.0096 0.0524 0.0521
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0064 0.0061
Schistosoma mansoni phosphatidylserine receptor 0.0036 0.0139 0.0139
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.0163 0.0951 0.0943
Schistosoma mansoni neuropeptide receptor 0.0157 0.0915 0.0915
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0022 0.0051 0.0044
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0022 0.0051 0.0611
Mycobacterium leprae conserved hypothetical protein 0.0145 0.0841 1
Echinococcus multilocularis cathepsin L 0.0207 0.1232 0.1225
Trypanosoma brucei acetyl-CoA carboxylase 0.0163 0.0951 0.1261
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0157 0.0915 0.0908
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0045 0.0539
Echinococcus granulosus tumor protein p63 0.0678 0.4247 0.4243
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0102
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.0841 0.0841
Schistosoma mansoni DNA polymerase eta 0.0039 0.0162 0.0162
Schistosoma mansoni N-myristoyltransferase 0.011 0.0614 0.0614
Echinococcus multilocularis dro:myosuppressin receptor 0.0157 0.0915 0.0908
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0064 0.0082
Onchocerca volvulus 0.0062 0.0309 0.0503
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0207 0.1232 0.1232
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0207 0.1232 0.2968
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0079 0.0079
Toxoplasma gondii cathepsin CPL 0.0932 0.5874 1
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0062 0.0307 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Schistosoma mansoni lamin 0.0027 0.0084 0.0084
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Echinococcus granulosus allatostatin A receptor 0.0157 0.0915 0.0908
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.081 0.0803
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0045 0.0045
Brugia malayi hypothetical protein 0.0075 0.0391 0.0388
Schistosoma mansoni myosin xvIII 0.0157 0.0915 0.0915
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0062 0.0307 0.0299
Plasmodium vivax unspecified product 0.0294 0.1792 0.3051
Loa Loa (eye worm) hypothetical protein 0.0099 0.0545 0.0542
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0051 0.0068
Plasmodium vivax serine-repeat antigen (SERA) 0.0207 0.1232 0.2098
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0157 0.0915 0.0908
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0207 0.1232 0.2098
Schistosoma mansoni hypothetical protein 0.003 0.0105 0.0105
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0067 0.006
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0016 0.0016 0.0012
Echinococcus granulosus biogenic amine 5HT receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0638 0.3992 0.399
Brugia malayi exodeoxyribonuclease III family protein 0.005 0.0231 0.0227
Onchocerca volvulus 0.0932 0.5874 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0097 0.0531 0.0523
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0145 0.0841 0.1408
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Trypanosoma cruzi cysteine peptidase, putative 0.0932 0.5874 0.5874
Echinococcus granulosus nmda type glutamate receptor 0.0057 0.0277 0.0269
Mycobacterium tuberculosis Probable esterase LipL 0.0145 0.0841 0.1408
Plasmodium falciparum serine repeat antigen 3 0.0207 0.1232 0.2098
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0016 0.0016 0.0008
Echinococcus multilocularis G-protein coupled receptor, putative 0.0157 0.0915 0.0908
Schistosoma mansoni phd/f-box containing protein 0.0036 0.0139 0.0139
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0045 0.006
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0064 0.0762
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0036 0.0139 0.0136
Onchocerca volvulus 0.0157 0.0915 0.1538
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0064 0.0762
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.081 0.0807
Brugia malayi intermediate filament protein 0.0027 0.0084 0.0081
Trypanosoma brucei unspecified product 0.0027 0.0084 0.0111
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0207 0.1232 0.2098
Echinococcus multilocularis serotonin receptor 0.0157 0.0915 0.0908
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus granulosus o acyltransferase membrane bound domain 0.0016 0.0016 0.0008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0157 0.0915 0.0915
Onchocerca volvulus 0.0145 0.0841 0.1411
Onchocerca volvulus 0.0157 0.0915 0.1538
Brugia malayi MH2 domain containing protein 0.0025 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1577 1 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0207 0.1232 0.2968
Echinococcus granulosus transient receptor potential cation channel 0.0166 0.0972 0.0965
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0162 0.0162
Mycobacterium ulcerans hypothetical protein 0.0024 0.0064 0.0762
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0145 0.0841 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Schistosoma mansoni cytochrome P450 0.0021 0.0045 0.0045
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0162 0.0159
Trypanosoma cruzi cysteine protease, putative 0.0501 0.3114 0.3114
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0028 0.0088 0.0123
Treponema pallidum exodeoxyribonuclease (exoA) 0.005 0.0231 1
Mycobacterium tuberculosis Probable hydrolase 0.0145 0.0841 0.1408
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0631 0.3944 0.523
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Brugia malayi jmjC domain containing protein 0.0136 0.0778 0.0775
Echinococcus granulosus glutamate receptor NMDA 0.005 0.023 0.0223
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0045 0.0539
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0035 0.0133 0.0201
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0187 0.0292
Echinococcus granulosus neuropeptide Y receptor 0.0157 0.0915 0.0908
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0064 0.0762
Echinococcus multilocularis transient receptor potential cation channel 0.0166 0.0974 0.0966
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Loa Loa (eye worm) cytochrome P450 family protein 0.0073 0.0379 0.0376
Schistosoma mansoni metabotropic glutamate receptor 0.0017 0.0021 0.0021
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0164 0.0196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0036 0.0144 0.0136
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0045 0.0045
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0033 0.012 0.0112
Brugia malayi Pre-SET motif family protein 0.0709 0.4444 0.4442
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0162 0.0215
Onchocerca volvulus 0.0807 0.5072 0.8631
Giardia lamblia Cysteine protease 0.0207 0.1232 0.2968
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.003 0.0105 0.0101
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0045 0.0539
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0157 0.0915 0.0915
Schistosoma mansoni jumonji/arid domain-containing protein 0.0136 0.0778 0.0778
Entamoeba histolytica glycylpeptide N-tetradecanoyltransferase, putative 0.011 0.0614 0.1021
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0025 0.0011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0022 0.0051 0.0076
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0207 0.1232 0.2076
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0033 0.012 0.0112
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.0163 0.0951 0.1618
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0064 0.0762
Echinococcus multilocularis Smad4 0.0025 0.0067 0.006
Brugia malayi latrophilin 2 splice variant baaae 0.0066 0.033 0.0327
Onchocerca volvulus Neuropeptide F receptor homolog 0.0157 0.0915 0.1538
Schistosoma mansoni cathepsin F (C01 family) 0.0638 0.3992 0.3992
Giardia lamblia Encystation-specific protease 0.0207 0.1232 0.2968
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.005 0.0231 0.0227
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.0841 0.0841
Plasmodium falciparum cysteine proteinase falcipain 1 0.0501 0.3114 0.5301
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0016 0.0016 0.0008
Giardia lamblia Cathepsin B precursor 0.0631 0.3944 1
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.006 0.0297 0.029
Brugia malayi cathepsin F-like cysteine proteinase 0.0207 0.1232 0.1229
Echinococcus granulosus cathepsin b 0.1577 1 1
Echinococcus granulosus phd:f box containing protein 0.0036 0.0139 0.0131
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Echinococcus multilocularis orexin receptor type 2 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi Cytochrome P450 family protein 0.0073 0.0379 0.0376
Loa Loa (eye worm) hypothetical protein 0.0036 0.0144 0.014
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0207 0.1232 0.2076
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0849 0.0849
Brugia malayi Doublecortin family protein 0.0016 0.0014 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0501 0.3114 0.5289
Echinococcus granulosus histone lysine methyltransferase setb 0.0102 0.0564 0.0557
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Brugia malayi follicle stimulating hormone receptor 0.0157 0.0915 0.0912
Brugia malayi Papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Schistosoma mansoni cathepsin C 0.0207 0.1232 0.1232
Chlamydia trachomatis biotin carboxylase 0.0056 0.027 1
Schistosoma mansoni lamin 0.0027 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0152 0.0883 0.088
Echinococcus granulosus metabotropic glutamate receptor 2 0.0026 0.0079 0.0071
Schistosoma mansoni neuropeptide F-like receptor 0.0157 0.0915 0.0915
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0564 0.0564
Plasmodium vivax serine-repeat antigen (SERA) 0.0207 0.1232 0.2098
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0109 0.0109
Giardia lamblia DINP protein human, muc B family 0.0039 0.0162 0.0192
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Echinococcus multilocularis lysine specific demethylase 5A 0.0134 0.0768 0.0761
Echinococcus granulosus neuropeptide receptor 0.0157 0.0915 0.0908
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni cathepsin F (C01 family) 0.0932 0.5874 0.5874
Brugia malayi Papain family cysteine protease containing protein 0.0501 0.3114 0.3112
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0096 0.0524 0.0521
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Echinococcus granulosus cathepsin b 0.1577 1 1
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0207 0.1232 0.2076
Onchocerca volvulus 0.0157 0.0915 0.1538
Echinococcus granulosus beta LACTamase domain containing family member 0.0145 0.0841 0.0834

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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