Detailed information for compound 781192

Basic information

Technical information
  • TDR Targets ID: 781192
  • Name: 6-Methyl-3-o-tolylamino-4H-[1,2,4]triazin-5-o ne
  • MW: 216.239 | Formula: C11H12N4O
  • H donors: 2 H acceptors: 4 LogP: 1.81 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccccc1Nc1nnc(c(n1)O)C
  • InChi: 1S/C11H12N4O/c1-7-5-3-4-6-9(7)12-11-13-10(16)8(2)14-15-11/h3-6H,1-2H3,(H2,12,13,15,16)
  • InChiKey: RSOTYHKDQPJEQS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-methyl-3-[(2-methylphenyl)amino]-1,2,4-triazin-5(4H)-one
  • MLS000062636
  • SMR000071173
  • Oprea1_263120
  • ST5190737
  • BAS 03013480
  • ZINC02615704

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0041 0.0012 0.0196
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0371 0.0428 0.0426
Mycobacterium tuberculosis Probable hydrolase 0.0155 0.0155 0.1273
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0186 0.0195 0.0194
Onchocerca volvulus 0.0126 0.0119 0.1941
Onchocerca volvulus 0.0084 0.0066 0.1068
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.0166 0.0163
Echinococcus multilocularis muscleblind protein 1 0.0303 0.0342 0.0339
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0371 0.0428 0.0426
Onchocerca volvulus 0.0051 0.0025 0.0393
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0042 0.0013 0.0369
Schistosoma mansoni lipoxygenase 0.0057 0.0032 0.0031
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0006 0.0102
Toxoplasma gondii exonuclease III APE 0.0039 0.001 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.0003 0.0008
Brugia malayi G-protein coupled receptor 0.0051 0.0025 0.0111
Brugia malayi Bromodomain containing protein 0.0043 0.0015 0.0064
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0094 0.0079 0.0077
Toxoplasma gondii histone lysine methyltransferase SET1 0.0568 0.0675 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0009 0.0239
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0025 0.0024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0003 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0102 0.0101
Trypanosoma brucei cAMP response protein 1, putative 0.0041 0.0012 0.0339
Mycobacterium tuberculosis Probable esterase LipL 0.0155 0.0155 0.1273
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.0025 0.0023
Trichomonas vaginalis hypothetical protein 0.0047 0.002 0.0321
Schistosoma mansoni importin beta-1 0.0247 0.0272 0.0271
Brugia malayi putative neuropeptide receptor 0.0051 0.0025 0.0111
Trichomonas vaginalis inositol monophosphatase, putative 0.0033 0.0002 0.0039
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0025 0.0023
Echinococcus granulosus orexin receptor type 2 0.0051 0.0025 0.0023
Plasmodium vivax hypothetical protein, conserved 0.0102 0.0089 0.3036
Brugia malayi hypoxia-induced factor 1 0.0484 0.057 0.2636
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0032 0.003
Echinococcus granulosus mixed lineage leukemia protein mll 0.0076 0.0057 0.0054
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0408 0.0475 0.0472
Giardia lamblia Kinase, CMGC MAPK 0.0112 0.0102 0.5186
Brugia malayi hypothetical protein 0.0525 0.0621 0.2873
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0012 0.0333
Schistosoma mansoni voltage-gated potassium channel 0.0309 0.035 0.0349
Mycobacterium leprae Conserved hypothetical protein 0.0041 0.0012 0.0311
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0102 0.0089 0.1463
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Plasmodium vivax metacaspase 1, putative 0.0102 0.0089 0.3036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0003 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0102 0.1673
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0012 0.0011
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0012 0.0009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0071 0.005 0.0047
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.001 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0745
Echinococcus granulosus tachykinin peptides receptor 99D 0.0051 0.0025 0.0023
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.0025 0.0023
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0041 0.0012 0.001
Echinococcus granulosus neuropeptide receptor 0.0051 0.0025 0.0023
Onchocerca volvulus 0.0116 0.0107 0.1732
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0041 0.0012 0.0339
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0164 0.0167 0.0165
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0084 0.0066 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0294 0.0331 0.033
Schistosoma mansoni neuropeptide receptor 0.0051 0.0025 0.0024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0025 0.0024
Trypanosoma brucei importin beta-1 subunit, putative 0.0247 0.0272 0.7591
Schistosoma mansoni hypothetical protein 0.0164 0.0167 0.0166
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0033 0.0003 0.0001
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.0003 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0102 0.1673
Echinococcus multilocularis glutamate receptor 2 0.0246 0.027 0.0268
Mycobacterium ulcerans hypothetical protein 0.0041 0.0012 0.013
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0314 0.5151
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0041 0.0012 0.0029
Echinococcus granulosus lamin dm0 0.0117 0.0109 0.0106
Schistosoma mansoni survival motor neuron protein 0.0098 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0102 0.0089 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0012 0.0199
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0025 0.0023
Echinococcus multilocularis tyrosine kinase 0.0128 0.0121 0.0119
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0041 0.0012 0.001
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.0025 0.0023
Brugia malayi Inositol monophosphatase family protein 0.0033 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0516 0.061 0.1854
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0012 0.0196
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.0025 0.0023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0318 0.0361 0.4783
Echinococcus multilocularis nmda type glutamate receptor 0.2891 0.3599 0.3598
Brugia malayi TAR-binding protein 0.0198 0.021 0.0968
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0012 0.0266
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0205 0.3363
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0059 0.0035 0.0578
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Brugia malayi larval opioid receptor 0.0051 0.0025 0.0111
Trypanosoma brucei protein kinase, putative 0.0112 0.0102 0.2852
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0041 0.0012 0.0011
Brugia malayi metabotropic glutamate receptor type 2 0.0126 0.0119 0.0547
Echinococcus multilocularis glutamate receptor 2 0.0371 0.0428 0.0426
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0006 0.0109
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.0025 0.0069
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0041 0.0012 0.0145
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0089 0.1463
Schistosoma mansoni amine GPCR 0.0051 0.0025 0.0024
Schistosoma mansoni protein kinase 0.0128 0.0121 0.012
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0294 0.0331 0.1526
Schistosoma mansoni neuropeptide receptor 0.0051 0.0025 0.0024
Echinococcus multilocularis snurportin 1 0.2638 0.3281 0.3279
Brugia malayi steroid hormone receptor 0.0033 0.0003 0.0008
Schistosoma mansoni caspase-3 (C14 family) 0.0177 0.0183 0.0182
Echinococcus multilocularis lamin dm0 0.0117 0.0109 0.0106
Echinococcus granulosus inositol monophosphatase 1 0.0316 0.0358 0.0356
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0041 0.0012 0.003
Trypanosoma cruzi metacaspase 5, putative 0.0102 0.0089 0.2494
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0025 0.0024
Brugia malayi Pre-SET motif family protein 0.0071 0.005 0.0226
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0041 0.0012 0.0507
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0314 0.5151
Onchocerca volvulus 0.0482 0.0567 0.9293
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0025 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0102 0.0089 0.1463
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0102 0.0089 0.1463
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0012 0.0199
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.0003 0.0027
Schistosoma mansoni cpg binding protein 0.0316 0.0359 0.0358
Trichomonas vaginalis ran, putative 0.0161 0.0163 0.2671
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Schistosoma mansoni alpha-glucosidase 0.014 0.0137 0.0136
Echinococcus multilocularis SAM and MBT domain containing protein 0.0102 0.0089 0.0086
Echinococcus granulosus ubiquitin specific protease 41 0.0186 0.0195 0.0192
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3414 0.4258 0.4256
Brugia malayi mbt repeat family protein 0.0102 0.0089 0.0406
Brugia malayi Serotonin receptor 0.0051 0.0025 0.0111
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0283 0.0316 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0191 0.0201 0.02
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.0003 0.0008
Schistosoma mansoni hypothetical protein 0.0051 0.0025 0.0024
Onchocerca volvulus 0.0051 0.0025 0.0393
Schistosoma mansoni glutamate receptor NMDA 0.2387 0.2966 0.2965
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0371 0.0428 0.0426
Brugia malayi F/Y-rich N-terminus family protein 0.0095 0.0081 0.0369
Brugia malayi Dopamine receptor protein 1 0.0051 0.0025 0.0111
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0003 0.0002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0063 0.004 0.0115
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0316 0.0358 1
Leishmania major hypothetical protein, conserved 0.0047 0.002 0.0479
Schistosoma mansoni tar DNA-binding protein 0.0198 0.021 0.0209
Onchocerca volvulus 0.0041 0.0012 0.0183
Loa Loa (eye worm) hypothetical protein 0.0079 0.0061 0.0178
Brugia malayi beta-lactamase family protein 0.0155 0.0155 0.0715
Loa Loa (eye worm) hypoxia-induced factor 1 0.0484 0.057 0.1732
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.001 0.0205
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.0025 0.0023
Echinococcus granulosus mitogen activated protein kinase 3 0.0112 0.0102 0.01
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0219 0.0236 0.3855
Brugia malayi CXXC zinc finger family protein 0.0297 0.0335 0.1544
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Trypanosoma cruzi Flagellar Member 6 0.0041 0.0012 0.0339
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0128 0.0121 0.1974
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.063 0.0753 0.6243
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Brugia malayi cytoplasmic intermediate filament protein 0.0063 0.004 0.018
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.0025 0.0023
Onchocerca volvulus 0.0051 0.0025 0.0393
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0006 0.0174
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0294 0.0331 0.033
Loa Loa (eye worm) hypothetical protein 0.0219 0.0236 0.0712
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0041 0.0012 0.013
Echinococcus granulosus hypothetical protein 0.0051 0.0025 0.0023
Leishmania major protein kinase, putative 0.0042 0.0013 0.0307
Brugia malayi G-protein coupled receptor 0.0051 0.0025 0.0111
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0025 0.0023
Brugia malayi Metabotropic glutamate receptor precursor. 0.0126 0.0119 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0013 0.0012
Brugia malayi Matrixin family protein 0.0055 0.0029 0.0131
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0246 0.027 0.0268
Loa Loa (eye worm) TAR-binding protein 0.0198 0.021 0.0634
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0012 0.0199
Echinococcus multilocularis muscleblind protein 0.0303 0.0342 0.0339
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0102 0.0089 0.1291
Leishmania major hypothetical protein, conserved 0.0041 0.0012 0.0272
Schistosoma mansoni tyrosine kinase 0.0128 0.0121 0.012
Loa Loa (eye worm) hypothetical protein 0.0155 0.0155 0.0467
Leishmania major hypothetical protein, conserved 0.0041 0.0012 0.0272
Echinococcus granulosus ephrin type A receptor 4 A 0.0148 0.0147 0.0144
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0006 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.0003 0.0008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0117 0.0109 0.0324
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0012 0.0189
Plasmodium falciparum cGMP-dependent protein kinase 0.0042 0.0013 0.0222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.0003 0.0001
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0041 0.0012 0.001
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0032 0.0885
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0482 0.0567 0.1723
Leishmania major GTP-binding protein, putative 0.0161 0.0163 0.4472
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Mycobacterium ulcerans regulatory protein 0.0041 0.0012 0.013
Echinococcus granulosus zinc finger protein 0.0039 0.001 0.0007
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0012 0.0049
Schistosoma mansoni alpha glucosidase 0.0036 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.02 0.0213 0.5921
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0059 0.0035 0.01
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0126 0.0119 0.0117
Schistosoma mansoni hypothetical protein 0.0033 0.0002 0.0001
Loa Loa (eye worm) ICD-1 protein 0.0041 0.0012 0.003
Onchocerca volvulus 0.0098 0.0084 0.1361
Loa Loa (eye worm) hypothetical protein 0.0084 0.0066 0.0194
Echinococcus multilocularis neuropeptide s receptor 0.6385 0.7997 0.7997
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.0025 0.0111
Loa Loa (eye worm) hypothetical protein 0.0057 0.0032 0.0091
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.0025 0.0069
Schistosoma mansoni ap endonuclease 0.0039 0.001 0.0009
Echinococcus granulosus muscleblind protein 0.0303 0.0342 0.0339
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0246 0.027 0.0268
Schistosoma mansoni lozenge 0.006 0.0037 0.0036
Schistosoma mansoni hypothetical protein 0.0626 0.0748 0.0747
Echinococcus multilocularis apoptotic protease activating factor 1 0.0174 0.018 0.0178
Loa Loa (eye worm) hypothetical protein 0.0115 0.0106 0.0316
Echinococcus granulosus glutamate receptor NMDA 0.2016 0.2498 0.2496
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0246 0.027 0.0268
Echinococcus granulosus survival motor neuron protein 1 0.048 0.0565 0.0562
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0059 0.0035 0.0033
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0318 0.0361 0.0359
Mycobacterium tuberculosis Probable lipase LipE 0.0155 0.0155 0.1273
Trypanosoma cruzi DNA polymerase eta, putative 0.0066 0.0044 0.1218
Mycobacterium tuberculosis Conserved protein 0.0155 0.0155 0.1273
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.0025 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0067 0.0045 0.0745
Schistosoma mansoni aldehyde dehydrogenase 0.0318 0.0361 0.036
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0025 0.0023
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0025 0.0023
Plasmodium vivax importin-beta 2, putative 0.0247 0.0272 1
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0003 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0012 0.0322
Treponema pallidum cyclic nucleotide binding protein 0.0041 0.0012 0.0032
Loa Loa (eye worm) hypothetical protein 0.0117 0.0109 0.0324
Brugia malayi PAS domain containing protein 0.0156 0.0158 0.0726
Schistosoma mansoni biogenic amine receptor 0.0051 0.0025 0.0024
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0041 0.0012 0.001
Echinococcus granulosus cGMP dependent protein kinase 1 0.0042 0.0013 0.0011
Echinococcus granulosus GPCR family 2 0.0164 0.0167 0.0165
Schistosoma mansoni myosin xvIII 0.0051 0.0025 0.0024
Echinococcus multilocularis dna polymerase eta 0.0066 0.0044 0.0041
Echinococcus granulosus glutamate NMDA receptor subunit 0.0246 0.027 0.0268
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0091 0.3144
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0085 0.0068 0.0065
Schistosoma mansoni intermediate filament proteins 0.0117 0.0109 0.0108
Loa Loa (eye worm) intermediate filament protein 0.0117 0.0109 0.0324
Trypanosoma brucei metacaspase MCA3 0.0102 0.0089 0.2494
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.0025 0.0024
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0155 0.0155 0.0467
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0006 0.0102
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0019 0.0017
Onchocerca volvulus 0.0051 0.0025 0.0393
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.001 0.0061
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.0025 0.0023
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.0025 0.0024
Brugia malayi Muscleblind-like protein 0.0303 0.0342 0.1578
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0012 0.0122
Schistosoma mansoni hypothetical protein 0.1062 0.1297 0.1296
Mycobacterium ulcerans hypothetical protein 0.0041 0.0012 0.013
Plasmodium falciparum basic transcription factor 3b, putative 0.0041 0.0012 0.0182
Onchocerca volvulus Huntingtin homolog 0.0516 0.061 0.9999
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0041 0.0012 0.0339
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0041 0.0012 0.0173
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0003 0.0002
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0076 0.0057 0.0054
Loa Loa (eye worm) hypothetical protein 0.0151 0.0151 0.0453
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.0003 0.0002
Brugia malayi bHLH-PAS transcription factor 0.0116 0.0107 0.0489
Brugia malayi Cell death protein 3 precursor 0.0276 0.0309 0.1425
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.0193 0.3159
Mycobacterium tuberculosis Probable lipase LipD 0.0155 0.0155 0.1273
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0012 0.0333
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0041 0.0012 0.0199
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0281 0.0314 0.0951
Onchocerca volvulus 0.0051 0.0025 0.0393
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.001 0.0082
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0155 0.0155 0.1273
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0102 0.0089 0.1463
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.0025 0.0024
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0006 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.0003 0.0001
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0041 0.0012 0.001
Loa Loa (eye worm) RGC/RGC protein kinase 0.0128 0.0121 0.0363
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.0025 0.0069
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0012 0.0322
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.0025 0.0024
Onchocerca volvulus 0.0155 0.0155 0.2536
Schistosoma mansoni DNA polymerase eta 0.0066 0.0044 0.0043
Echinococcus granulosus neuropeptide receptor A26 0.6385 0.7997 0.7997
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0041 0.0012 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0745
Schistosoma mansoni hypothetical protein 0.0051 0.0025 0.0024
Entamoeba histolytica hypothetical protein 0.0037 0.0008 0.0145
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0006 0.0109
Schistosoma mansoni myst-related protein 0.0037 0.0008 0.0007
Schistosoma mansoni ran 0.0161 0.0163 0.0162
Trypanosoma cruzi transcription factor btf3, putative 0.0041 0.0012 0.0345
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.0025 0.0023
Echinococcus granulosus hyperpolarization activated cyclic 0.0059 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0065 0.0042 0.0122
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0161 0.0163 0.5847
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0074 0.0073
Schistosoma mansoni hypothetical protein 0.0164 0.0167 0.0166
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0112 0.0102 0.0304
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0025 0.0023
Brugia malayi beta-NAC-like protein 0.0041 0.0012 0.0053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0025 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0745
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0006 0.0174
Echinococcus multilocularis importin 5 0.0047 0.002 0.0017
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0085 0.0068 0.0308
Schistosoma mansoni tar DNA-binding protein 0.0198 0.021 0.0209
Schistosoma mansoni sex comb on midleg homolog 0.0102 0.0089 0.0088
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0033 0.0002 0.0067
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0041 0.0012 0.0052
Echinococcus multilocularis mitogen activated protein kinase 0.0112 0.0102 0.01
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0298 0.0336 0.0333
Echinococcus granulosus somatostatin receptor 0.0051 0.0025 0.0023
Schistosoma mansoni inositol monophosphatase 0.0316 0.0358 0.0357
Trichomonas vaginalis helicase, putative 0.0067 0.0045 0.0745
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Brugia malayi Amyloid A4 extracellular domain containing protein 0.061 0.0728 0.3367
Loa Loa (eye worm) glutamate receptor 1 0.0246 0.027 0.0816
Echinococcus granulosus serotonin receptor 0.0051 0.0025 0.0023
Loa Loa (eye worm) RNA binding protein 0.0198 0.021 0.0634
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0059 0.0035 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0003 0.0008
Brugia malayi hypothetical protein 0.0174 0.018 0.0829
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0082 0.0064 0.0062
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0003 0.0002
Schistosoma mansoni coup transcription factor 0.0033 0.0003 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Mycobacterium ulcerans transcriptional regulatory protein 0.0041 0.0012 0.013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0025 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0041 0.0012 0.0011
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0116 0.0106 0.0104
Echinococcus granulosus SAM and MBT domain containing protein 0.0102 0.0089 0.0086
Loa Loa (eye worm) hypothetical protein 0.0146 0.0145 0.0434
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0041 0.0012 0.001
Leishmania major protein kinase, putative 0.0042 0.0013 0.0302
Echinococcus granulosus cGMP dependent protein kinase 1 0.0042 0.0013 0.0011
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0059 0.0035 0.0033
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0186 0.0195 0.0194
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0068 0.0067
Echinococcus multilocularis importin subunit beta 1 0.0247 0.0272 0.0269
Echinococcus granulosus hyperpolarization activated cyclic 0.0059 0.0035 0.0033
Schistosoma mansoni lamin 0.0117 0.0109 0.0108
Trichomonas vaginalis hypothetical protein 0.0034 0.0003 0.0055
Leishmania major basic transcription factor 3a, putative 0.0041 0.0012 0.0278
Leishmania major cathepsin L-like protease 0.0072 0.0051 0.1354
Echinococcus multilocularis microtubule associated protein 2 0.7977 1 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.0166 0.0498
Echinococcus granulosus polycomb protein SCMH1 0.0102 0.0089 0.0086
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0041 0.0012 0.0145
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Trichomonas vaginalis penicillin-binding protein, putative 0.0155 0.0155 0.2548
Trypanosoma brucei Metacaspase-4 0.0102 0.0089 0.2494
Echinococcus multilocularis Protein lozenge 0.006 0.0037 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0314 0.5151
Echinococcus multilocularis aryl hydrocarbon receptor 0.0041 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0039
Onchocerca volvulus 0.0297 0.0335 0.5475
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0059 0.0035 0.0034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0076 0.0057 0.0054
Echinococcus multilocularis hyperpolarization activated cyclic 0.0059 0.0035 0.0033
Echinococcus multilocularis nmda type glutamate receptor 0.2142 0.2656 0.2655
Onchocerca volvulus 0.0041 0.0012 0.0179
Echinococcus granulosus g protein coupled receptor 0.0051 0.0025 0.0023
Onchocerca volvulus 0.0051 0.0025 0.0393
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Trichomonas vaginalis D-aminoacylase, putative 0.0155 0.0155 0.2548
Trypanosoma brucei metacaspase 5, putative 0.0102 0.0089 0.2494
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0041 0.0012 0.0011
Schistosoma mansoni ATP-binding cassette transporter 0.0246 0.027 0.0269
Echinococcus multilocularis dna polymerase kappa 0.004 0.0012 0.0009
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0164 0.0167 0.0502
Echinococcus multilocularis glutamate receptor NMDA 0.2016 0.2498 0.2496
Loa Loa (eye worm) inositol-1 0.0316 0.0358 0.1085
Loa Loa (eye worm) hypothetical protein 0.0041 0.0012 0.0029
Onchocerca volvulus 0.0051 0.0025 0.0393
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Schistosoma mansoni hypothetical protein 0.0164 0.0167 0.0166
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0047 0.002 0.0503
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0316 0.0358 0.5867
Echinococcus multilocularis musashi 0.0117 0.0109 0.0106
Brugia malayi RNA recognition motif domain containing protein 0.0198 0.021 0.0968
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.0025 0.0111
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0059 0.0035 0.0033
Echinococcus multilocularis ubiquitin specific protease 41 0.0186 0.0195 0.0192
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0012 0.0189
Leishmania major metacaspase, putative 0.0102 0.0089 0.242
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.001 0.004
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0174 0.018 0.0542
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0012 0.0202
Loa Loa (eye worm) hypothetical protein 0.0155 0.0155 0.0467
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.0025 0.0393
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0066 0.0064
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.0025 0.0024
Echinococcus granulosus transcription factor btf3 0.0041 0.0012 0.001
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0041 0.0012 0.0052
Loa Loa (eye worm) hypothetical protein 0.0303 0.0342 0.1035
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.0025 0.0023
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0161 0.0163 0.4552
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0067 0.0045 0.0745
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0071 0.005 0.0049
Leishmania major DNA polymerase eta, putative 0.0038 0.0009 0.0172
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0006 0.0102
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0283 0.0316 0.2611
Echinococcus granulosus receptor type guanylyl cyclase 0.0128 0.0121 0.0119
Loa Loa (eye worm) hypothetical protein 0.048 0.0565 0.1717
Echinococcus granulosus fmrfamide receptor 0.0051 0.0025 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0294 0.0331 0.0328
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0191 0.0201 0.0198
Schistosoma mansoni hypothetical protein 0.3822 0.4771 0.4771
Schistosoma mansoni biogenic amine receptor 0.0051 0.0025 0.0024
Brugia malayi Bromodomain containing protein 0.0101 0.0088 0.0403
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.0025 0.0023
Schistosoma mansoni amine GPCR 0.0051 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0074 0.0054 0.0159
Mycobacterium leprae Probable lipase LipE 0.0155 0.0155 0.4876
Echinococcus granulosus GTP binding nuclear protein Ran 0.0161 0.0163 0.0161
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.001 0.0272
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.001 0.0207
Onchocerca volvulus 0.0071 0.005 0.08
Echinococcus granulosus importin subunit beta 1 0.0247 0.0272 0.0269
Echinococcus multilocularis NMDA receptor 0.0246 0.027 0.0268
Toxoplasma gondii ABC1 family protein 0.0155 0.0155 0.2275
Schistosoma mansoni glutamate receptor AMPA 0.0246 0.027 0.0269
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.0193 0.3159
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0186 0.0195 0.5355
Onchocerca volvulus 0.0146 0.0145 0.236
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0071 0.005 0.0049
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0042 0.0013 0.0369
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0041 0.0012 0.0081
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0025 0.0023
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0186 0.0195 0.0192
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.0025 0.0111
Schistosoma mansoni metabotropic glutamate receptor 0.0126 0.0119 0.0118
Brugia malayi Guanylyl cyclase protein 23 0.0128 0.0121 0.0557
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0112 0.0102 0.2777
Loa Loa (eye worm) hypothetical protein 0.0516 0.061 0.1854
Onchocerca volvulus Matrilysin homolog 0.005 0.0024 0.0373
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.001 0.0007
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0032 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0025 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0314 0.5151
Mycobacterium leprae conserved hypothetical protein 0.0155 0.0155 0.4876
Onchocerca volvulus 0.0128 0.0121 0.1974
Leishmania major hypothetical protein, conserved 0.0155 0.0155 0.4264
Plasmodium vivax SET domain protein, putative 0.0071 0.005 0.1527
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0067 0.0045 0.0745
Echinococcus multilocularis neuropeptide receptor A26 0.6385 0.7997 0.7997
Brugia malayi Ets-domain containing protein 0.0074 0.0054 0.0247
Onchocerca volvulus 0.0151 0.0151 0.246
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0012 0.0257
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0186 0.0195 0.0192
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.0025 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.0003 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0022 0.006
Echinococcus granulosus metabotropic glutamate receptor 5 0.0126 0.0119 0.0117
Echinococcus granulosus caspase 3 0.0075 0.0055 0.0052
Mycobacterium ulcerans lipase LipD 0.0155 0.0155 0.2039
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Loa Loa (eye worm) latrophilin receptor protein 2 0.0164 0.0167 0.0502
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0041 0.0012 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0112 0.0102 0.2852
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0745
Echinococcus granulosus cGMP dependent protein kinase 0.0042 0.0013 0.0011
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0161 0.0163 0.835
Trypanosoma cruzi metacaspase, putative 0.0102 0.0089 0.2494
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0012 0.0196
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0033 0.0002 0.0067
Brugia malayi Cyclic-nucleotide gated cation channel 0.0059 0.0035 0.0159
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.001 0.0272
Leishmania major cathepsin L-like protease 0.0072 0.0051 0.1354
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0012 0.0196
Schistosoma mansoni aryl hydrocarbon receptor 0.0156 0.0158 0.0157
Loa Loa (eye worm) matrixin family protein 0.005 0.0024 0.0065
Brugia malayi MH2 domain containing protein 0.0251 0.0277 0.1276
Loa Loa (eye worm) glutamate receptor 2 0.0246 0.027 0.0816
Echinococcus granulosus g protein coupled receptor 0.0051 0.0025 0.0023
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0033 0.0002 0.0067
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0003 0.0008
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0009 0.0092
Echinococcus multilocularis caspase 3 0.0075 0.0055 0.0052
Schistosoma mansoni caspase-7 (C14 family) 0.0177 0.0183 0.0182
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0155 0.0155 0.0715
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0012 0.0339
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0055 0.0029 0.0082
Loa Loa (eye worm) matrixin family protein 0.0055 0.0029 0.0082
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0012 0.0322
Brugia malayi neuropeptide F receptor 0.0051 0.0025 0.0111
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0041 0.0012 0.0339
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0012 0.0011
Schistosoma mansoni bromodomain containing protein 0.0088 0.0072 0.0071
Onchocerca volvulus 0.0041 0.0012 0.0183
Mycobacterium ulcerans beta-lactamase 0.0155 0.0155 0.2039
Schistosoma mansoni adenoreceptor 0.0051 0.0025 0.0024
Schistosoma mansoni hypothetical protein 0.0164 0.0167 0.0166
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.007 0.0048 0.0046
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0094 0.0079 0.0077
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0041 0.0012 0.001
Onchocerca volvulus 0.0117 0.0109 0.1767
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0082 0.0064 0.0062
Echinococcus granulosus aryl hydrocarbon receptor 0.0041 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0012 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Echinococcus granulosus geminin 0.1062 0.1297 0.1295
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0518 0.0613 0.1862
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0316 0.0358 1
Schistosoma mansoni 60S ribosomal protein L21 0.0044 0.0016 0.0015
Echinococcus granulosus allatostatin A receptor 0.0051 0.0025 0.0023
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0039 0.0036
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0041 0.0012 0.0145
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0102 0.0089 0.1291
Loa Loa (eye worm) hypothetical protein 0.0174 0.018 0.0542
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.0003 0.0002
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0006 0.0012
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0316 0.0358 0.4737
Loa Loa (eye worm) hypothetical protein 0.0033 0.0003 0.0001
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.0025 0.0111
Echinococcus multilocularis somatostatin receptor 0.0051 0.0025 0.0023
Echinococcus multilocularis transfer RNA-Lys 0.0116 0.0107 0.0104
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0161 0.0163 0.5882
Mycobacterium ulcerans hypothetical protein 0.0155 0.0155 0.2039
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0025 0.0024
Trypanosoma brucei hypothetical protein, conserved 0.0155 0.0155 0.4343
Trichomonas vaginalis guanylate cyclase, putative 0.0041 0.0012 0.0196
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0041 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0247 0.0272 0.0822
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0102 0.0089 0.0265
Schistosoma mansoni glutamate receptor AMPA 0.0246 0.027 0.0269
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0051 0.0025 0.0024
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.001 0.0159
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0112 0.0102 0.2852
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0155 0.0155 0.1273
Brugia malayi RE15519p 0.0051 0.0025 0.0111
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0191 0.0201 0.5524
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0012 0.0196
Echinococcus granulosus apoptotic protease activating factor 1 0.0174 0.018 0.0178
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0025 0.0023
Echinococcus granulosus nmda type glutamate receptor 0.2891 0.3599 0.3598
Brugia malayi Serotonin receptor 0.0051 0.0025 0.0111
Brugia malayi hypothetical protein 0.0067 0.0045 0.0202
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0006 0.0102
Onchocerca volvulus 0.0051 0.0025 0.0393
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1748 0.216 0.6583
Trypanosoma cruzi hypothetical protein, conserved 0.0155 0.0155 0.4343
Schistosoma mansoni tar DNA-binding protein 0.0198 0.021 0.0209
Echinococcus multilocularis receptor type guanylyl cyclase 0.0128 0.0121 0.0119
Brugia malayi Dopamine receptor protein 2 0.0051 0.0025 0.0111
Schistosoma mansoni tyrosine kinase 0.0128 0.0121 0.012
Echinococcus multilocularis polycomb protein SCMH1 0.0102 0.0089 0.0086
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0283 0.0317 0.0315
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0041 0.0012 0.0339
Onchocerca volvulus 0.0155 0.0155 0.2536
Loa Loa (eye worm) hypothetical protein 0.009 0.0074 0.0218
Brugia malayi Ets-domain containing protein 0.0074 0.0054 0.0247
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0454 0.0532 0.1616
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0059 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0033 0.0003 0.0001
Leishmania major protein kinase, putative 0.0083 0.0065 0.1733
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.063 0.0753 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0012 0.0076
Echinococcus granulosus g-protein coupled receptor 0.0051 0.0025 0.0023
Schistosoma mansoni myo inositol monophosphatase 0.0033 0.0002 0.0001
Brugia malayi hypothetical protein 0.007 0.0048 0.0219
Brugia malayi Melatonin receptor type 1A 0.0051 0.0025 0.0111
Plasmodium vivax basic transcription factor 3b, putative 0.0041 0.0012 0.01
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0155 0.0155 0.0467
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0126 0.0119 0.0117
Plasmodium vivax hypothetical protein, conserved 0.0155 0.0155 0.5562
Echinococcus granulosus lamin 0.0117 0.0109 0.0106
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0012 0.0196
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0067 0.0045 0.0745
Trichomonas vaginalis adenylate cyclase, putative 0.0041 0.0012 0.0196
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0066 0.0065
Trichomonas vaginalis esterase, putative 0.0155 0.0155 0.2548
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0745
Brugia malayi ORL1-like opioid receptor 0.0051 0.0025 0.0111
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0012 0.0322
Echinococcus multilocularis inositol monophosphatase 1 0.0316 0.0358 0.0356
Toxoplasma gondii HEAT repeat-containing protein 0.0047 0.002 0.0256
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0085 0.0068 0.0199
Schistosoma mansoni transcription factor btf3 0.0041 0.0012 0.0011
Brugia malayi hypothetical protein 0.0516 0.061 0.2821
Schistosoma mansoni amine GPCR 0.0051 0.0025 0.0024
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0164 0.0167 0.0769
Mycobacterium tuberculosis Conserved protein 0.0041 0.0012 0.0081
Echinococcus granulosus metabotropic glutamate receptor 2 0.0126 0.0119 0.0117
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0166 0.0163
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0042 0.0013 0.0369
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0186 0.0195 0.0192
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0091 0.3144
Schistosoma mansoni amine GPCR 0.0051 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0003 0.0001
Echinococcus multilocularis transcription factor btf3 0.0041 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0059 0.0035 0.01
Schistosoma mansoni hypothetical protein 0.0051 0.0025 0.0024
Brugia malayi N-terminal motif family protein 0.0219 0.0236 0.1087
Brugia malayi Dopamine receptor 0.0051 0.0025 0.0111
Loa Loa (eye worm) glutamate receptor 0.0126 0.0119 0.0356
Treponema pallidum cyclic nucleotide binding protein 0.0041 0.0012 0.0032
Loa Loa (eye worm) hypothetical protein 0.0186 0.0195 0.0586
Schistosoma mansoni glutamate receptor kainate 0.0246 0.027 0.0269
Brugia malayi RNA, U transporter 1 0.0703 0.0845 0.3909
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Plasmodium vivax transportin, putative 0.0047 0.002 0.0376
Entamoeba histolytica Ran family GTPase 0.0161 0.0163 0.4515
Loa Loa (eye worm) AGC/PKG protein kinase 0.0042 0.0013 0.0034
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0112 0.0102 0.1482
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0041 0.0012 0.0092
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0006 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.0195 0.319
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0102 0.0089 0.1463
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0013 0.0012
Toxoplasma gondii NAC domain-containing protein 0.0041 0.0012 0.0148
Onchocerca volvulus 0.0051 0.0025 0.0393
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0059 0.0035 0.0034
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0191 0.0201 0.0198
Schistosoma mansoni cpg binding protein 0.0316 0.0359 0.0358
Loa Loa (eye worm) importin-beta domain-containing protein 0.0047 0.002 0.0052
Onchocerca volvulus 0.0155 0.0155 0.2536
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0025 0.0024
Mycobacterium ulcerans transmembrane transport protein 0.0041 0.0012 0.013
Echinococcus granulosus tar DNA binding protein 0.0198 0.021 0.0208
Loa Loa (eye worm) hypothetical protein 0.0033 0.0003 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0025 0.0023
Mycobacterium leprae Possible regulatory protein 0.0041 0.0012 0.0304
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0041 0.0012 0.0199
Trichomonas vaginalis Importin beta-1 subunit, putative 0.02 0.0213 0.349
Brugia malayi Latrophilin receptor protein 2 0.0164 0.0167 0.0769
Plasmodium falciparum transportin 0.0047 0.002 0.0455
Brugia malayi GnHR receptor homolog 0.0051 0.0025 0.0111
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0042 0.0014 0.0013
Leishmania major hypothetical protein, conserved 0.0041 0.0012 0.0272
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Onchocerca volvulus Huntingtin homolog 0.0516 0.061 0.9999
Echinococcus multilocularis transportin 1 0.0047 0.002 0.0017
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0041 0.0012 0.0092
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0222 0.0241 0.024
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0318 0.0361 0.0359
Echinococcus granulosus dna polymerase kappa 0.004 0.0012 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.0003 0.0001
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0047 0.002 0.0547
Mycobacterium ulcerans hypothetical protein 0.0041 0.0012 0.013
Trichomonas vaginalis D-aminoacylase, putative 0.0155 0.0155 0.2548
Brugia malayi Egg laying defective protein 4 0.0042 0.0013 0.0057
Trypanosoma brucei metacaspase MCA2 0.0102 0.0089 0.2494
Trypanosoma brucei protein kinase A regulatory subunit 0.0041 0.0012 0.0339
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0048 0.0021 0.0582
Leishmania major hypothetical protein, unknown function 0.0041 0.0012 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0025 0.0023
Trypanosoma brucei unspecified product 0.004 0.0012 0.0322
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0012 0.0081
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Loa Loa (eye worm) fli-1 protein 0.0226 0.0245 0.074
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0126 0.0119 0.0547
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0164 0.0167 0.0165
Schistosoma mansoni glutamate receptor kainate 0.0246 0.027 0.0269
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0059 0.0035 0.0033
Schistosoma mansoni hypothetical protein 0.0246 0.027 0.0269
Trypanosoma cruzi cAMP response protein 1, putative 0.0041 0.0012 0.0339
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0025 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Toxoplasma gondii aldehyde dehydrogenase 0.0318 0.0361 0.5337
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0371 0.0428 0.0426
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0054 0.0052
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0025 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0012 0.0322
Leishmania major extracellular receptor, putative 0.0126 0.0119 0.3254
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0041 0.0012 0.0145
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0102 0.0089 0.1291
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0126 0.0119 0.0356
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0314 0.5151
Loa Loa (eye worm) RGC/RGC protein kinase 0.0128 0.0121 0.0363
Loa Loa (eye worm) hypothetical protein 0.0103 0.0091 0.0269
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.0003 0.0001
Echinococcus granulosus patatin phospholipase domain containing protein 0.0041 0.0012 0.001
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0126 0.0119 0.0117
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.0025 0.0023
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0025 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.0003 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0051 0.1424
Trypanosoma brucei cAMP binding protein, putative 0.0041 0.0012 0.0339
Brugia malayi hypothetical protein 0.0482 0.0567 0.2621
Loa Loa (eye worm) hypothetical protein 0.0354 0.0406 0.1232
Schistosoma mansoni single-minded 0.0156 0.0158 0.0157
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.0003 0.0027
Leishmania major DNA polymerase kappa, putative 0.004 0.0012 0.0255
Leishmania major importin beta-1 subunit, putative 0.02 0.0213 0.5864
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0025 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0012 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0089 0.1463
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.0003 0.0008
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0041 0.0012 0.0011
Leishmania major DNA polymerase eta, putative 0.0066 0.0044 0.1148
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0318 0.0361 0.2986
Trypanosoma cruzi hypothetical protein, conserved 0.0155 0.0155 0.4343
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0745
Echinococcus granulosus glutamate receptor 2 0.0371 0.0428 0.0426
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0041 0.0012 0.001
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0186 0.0195 0.0897
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.0003 0.0008
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0161 0.0163 0.4552
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0294 0.0331 0.1001
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0102 0.0089 0.0088
Schistosoma mansoni tsg101-related 0.0058 0.0034 0.0033
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0012 0.0122
Brugia malayi ephrin receptor 1 precursor 0.0071 0.005 0.0225
Schistosoma mansoni ap endonuclease 0.0039 0.001 0.0009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0025 0.0024
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.001 0.0159
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Onchocerca volvulus Cell death protein 3 homolog 0.0276 0.0309 0.505
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0033 0.0002 0.0067
Loa Loa (eye worm) hypothetical protein 0.048 0.0565 0.1715
Echinococcus granulosus caspase 8 0.0102 0.0089 0.0087
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0025 0.0023
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.0003 0.0001
Brugia malayi RNA binding protein 0.0198 0.021 0.0968
Brugia malayi PHD-finger family protein 0.0045 0.0017 0.0075
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0164 0.0167 0.0165
Chlamydia trachomatis glutamine binding protein 0.063 0.0753 1
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0126 0.0119 0.0356
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0006 0.0057
Echinococcus multilocularis dnaJ subfamily B 0.3822 0.4771 0.477
Echinococcus multilocularis lamin 0.0117 0.0109 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0089 0.1463
Brugia malayi hypothetical protein 0.048 0.0565 0.261
Trypanosoma brucei importin beta-1 subunit, putative 0.0247 0.0272 0.7591
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0316 0.0358 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.001 0.0007
Trichomonas vaginalis set domain proteins, putative 0.0516 0.061 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0318 0.0361 1
Schistosoma mansoni hypothetical protein 0.0041 0.0012 0.0011
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.0003 0.0027
Trichomonas vaginalis Importin beta-1 subunit, putative 0.02 0.0213 0.349
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0191 0.0201 0.2642
Brugia malayi follicle stimulating hormone receptor 0.1748 0.216 1
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0089 0.1463
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0186 0.0195 0.319
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.0025 0.0393
Schistosoma mansoni amine GPCR 0.0051 0.0025 0.0024
Leishmania major cathepsin L-like protease 0.0072 0.0051 0.1354
Echinococcus multilocularis translational activator gcn1 0.0047 0.002 0.0017
Entamoeba histolytica hypothetical protein 0.0041 0.0012 0.028
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0745
Brugia malayi Glutamate receptor 2 precursor 0.0246 0.027 0.1245
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0294 0.0331 0.0328
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0041 0.0012 0.0011
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0164 0.0167 0.0165
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0006 0.0102
Trypanosoma brucei transcription factor BTF3, putative 0.0041 0.0012 0.0345
Loa Loa (eye worm) hypothetical protein 0.0033 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0482 0.0567 0.1723
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.0067 0.1831
Schistosoma mansoni hypothetical protein 0.0098 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0064 0.0041 0.0117
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.001 0.0098
Schistosoma mansoni ran 0.0161 0.0163 0.0162
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0246 0.027 0.0268
Brugia malayi Intermediate filament tail domain containing protein 0.0117 0.0109 0.0498
Onchocerca volvulus 0.0051 0.0025 0.0393
Trichomonas vaginalis importin beta-1, putative 0.02 0.0213 0.349
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0006 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0025 0.0024
Schistosoma mansoni hypothetical protein 0.0354 0.0406 0.0405
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0013 0.0012
Brugia malayi Importin beta-1 subunit 0.0247 0.0272 0.1254
Trypanosoma brucei DNA polymerase eta, putative 0.0066 0.0044 0.1218
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.0067 0.1831
Loa Loa (eye worm) hypothetical protein 0.0155 0.0155 0.0467
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0085 0.0068 0.0065
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0066 0.0064
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0042 0.0013 0.0369
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0042 0.0014 0.0012
Echinococcus granulosus cpg binding protein 0.0316 0.0359 0.0356
Mycobacterium ulcerans putative regulatory protein 0.0116 0.0107 0.1387
Trypanosoma brucei Flagellar Member 6 0.0041 0.0012 0.0339
Echinococcus multilocularis histone acetyltransferase MYST2 0.0116 0.0106 0.0104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0102 0.1673
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0041 0.0012 0.0081
Echinococcus multilocularis geminin 0.1062 0.1297 0.1295
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.0025 0.0023
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0186 0.0195 0.5438
Echinococcus multilocularis expressed conserved protein 0.0042 0.0013 0.0011
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0033 0.0002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0126 0.0119 0.0356
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Schistosoma mansoni histamine h1 receptor 0.0051 0.0025 0.0024
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0012 0.0322
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0019 0.0017
Brugia malayi ecdysteroid receptor 0.0033 0.0003 0.0008
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0265 0.0294 0.4823
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Onchocerca volvulus 0.0051 0.0025 0.0393
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0071 0.005 0.0704
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0025 0.0024
Onchocerca volvulus 0.0516 0.061 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.0025 0.0069
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0067 0.0045 0.0745
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0186 0.0195 0.319
Plasmodium vivax ataxin-2 like protein, putative 0.0103 0.0091 0.3087
Loa Loa (eye worm) hypothetical protein 0.007 0.0048 0.014
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0012 0.0009
Echinococcus granulosus mitogen activated protein kinase 0.0112 0.0102 0.01
Onchocerca volvulus 0.0051 0.0025 0.0393
Mycobacterium ulcerans aldehyde dehydrogenase 0.0318 0.0361 0.4783
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0041 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Brugia malayi AKH receptor 0.0051 0.0025 0.0111
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0371 0.0428 0.0426
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0632 0.0757 0.0756
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0025 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0006 0.0102
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0025 0.0023
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0112 0.0102 0.2852
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0745
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0126 0.0119 0.0356
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.2638 0.3281 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0025 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0198 0.021 0.0209
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0298 0.0336 0.0333
Onchocerca volvulus Matrix metalloproteinase homolog 0.005 0.0024 0.0373
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.0003 0.0001
Loa Loa (eye worm) MBCTL1 0.0116 0.0106 0.0317
Schistosoma mansoni hypothetical protein 0.1062 0.1297 0.1296
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.0193 0.3159
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0294 0.0331 0.0328
Echinococcus granulosus fetal alzheimer antigen falz 0.0042 0.0014 0.0012
Brugia malayi nuclear receptor NHR-88 0.0033 0.0003 0.0008
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0155 0.0155 0.1273
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0041 0.0012 0.001
Mycobacterium tuberculosis Conserved protein 0.0155 0.0155 0.1273
Mycobacterium ulcerans hypothetical protein 0.0041 0.0012 0.013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.0003 0.0001
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.0003 0.0002
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0112 0.0102 0.2852
Trypanosoma cruzi metacaspase 5, putative 0.0102 0.0089 0.2494
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.0193 0.3159
Schistosoma mansoni opsin-like receptor 0.0051 0.0025 0.0024
Onchocerca volvulus 0.0117 0.0109 0.1767
Loa Loa (eye worm) mbt repeat family protein 0.0102 0.0089 0.0263
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0265 0.0294 0.4823
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0025 0.0024
Echinococcus multilocularis mitogen activated protein kinase 3 0.0112 0.0102 0.01
Schistosoma mansoni hypothetical protein 0.0174 0.018 0.0179
Loa Loa (eye worm) hypothetical protein 0.0085 0.0067 0.0199
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.063 0.0753 1
Schistosoma mansoni hypothetical protein 0.0051 0.0025 0.0024
Trypanosoma brucei glucosidase, putative 0.0036 0.0006 0.0174
Leishmania major cyclic nucleotide-binding protein-like protein 0.0041 0.0012 0.0272
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0303 0.0342 0.1035
Echinococcus granulosus sex peptide receptor 0.0051 0.0025 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0012 0.0202
Echinococcus granulosus translational activator gcn1 0.0047 0.002 0.0017
Toxoplasma gondii HEAT repeat-containing protein 0.0047 0.002 0.0256
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0041 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0128 0.0121 0.0363
Loa Loa (eye worm) hypothetical protein 0.0046 0.0018 0.0049
Trypanosoma cruzi cAMP response protein 1 0.0041 0.0012 0.0339
Schistosoma mansoni glutamate receptor NMDA 0.0246 0.027 0.0269
Schistosoma mansoni hypothetical protein 0.2638 0.3281 0.328
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0041 0.0012 0.0196
Schistosoma mansoni biogenic amine receptor 0.0051 0.0025 0.0024
Brugia malayi latrophilin 2 splice variant baaae 0.0354 0.0406 0.1877
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0051 0.0025 0.0111
Entamoeba histolytica hypothetical protein 0.0126 0.0119 0.3286
Schistosoma mansoni alpha-glucosidase 0.014 0.0137 0.0136
Echinococcus granulosus atrial natriuretic peptide receptor 0.0126 0.0119 0.0117
Brugia malayi Receptor family ligand binding region containing protein 0.0126 0.0119 0.0547
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0161 0.0163 0.075
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0059 0.0035 0.01
Treponema pallidum catabolite gene activator 0.0041 0.0012 0.0032
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0025 0.0023
Echinococcus granulosus neuropeptide receptor 0.0051 0.0025 0.0023
Giardia lamblia DINP protein human, muc B family 0.004 0.0012 0.0476
Trichomonas vaginalis guanylate cyclase, putative 0.0041 0.0012 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0003 0.0008
Loa Loa (eye worm) RGC/RGC protein kinase 0.0128 0.0121 0.0363
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Brugia malayi neuropeptide F receptor 0.0051 0.0025 0.0111
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0059 0.0035 0.0034
Schistosoma mansoni aldehyde dehydrogenase 0.0318 0.0361 0.036
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0126 0.0119 0.0356
Echinococcus multilocularis serotonin receptor 0.0051 0.0025 0.0023
Trypanosoma cruzi importin beta-1 subunit, putative 0.02 0.0213 0.5948
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.0025 0.0111
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.009 0.0074 0.0071
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0102 0.0089 0.1463
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0186 0.0195 0.0192
Echinococcus granulosus transportin 1 0.0047 0.002 0.0017
Echinococcus granulosus beta LACTamase domain containing family member 0.0155 0.0155 0.0153
Brugia malayi Cytochrome P450 family protein 0.0049 0.0022 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0089 0.1463
Echinococcus granulosus glutamate receptor 2 0.0126 0.0119 0.0117
Schistosoma mansoni inositol monophosphatase 0.0316 0.0358 0.0357
Echinococcus granulosus tyrosine kinase 0.0128 0.0121 0.0119
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0316 0.0358 0.5867
Echinococcus multilocularis glutamate receptor 2 0.0126 0.0119 0.0117
Loa Loa (eye worm) hypothetical protein 0.0126 0.0119 0.0356
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0371 0.0428 0.0426
Schistosoma mansoni ets-related 0.0226 0.0245 0.0244
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0283 0.0317 0.1465
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0518 0.0613 0.2833
Brugia malayi beta-lactamase 0.0155 0.0155 0.0715
Brugia malayi Fli-1 protein 0.0226 0.0245 0.1129
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0246 0.027 0.0268
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0102 0.0089 0.1463
Trypanosoma cruzi cAMP binding protein, putative 0.0041 0.0012 0.0339
Brugia malayi nuclear hormone receptor 0.0033 0.0003 0.0008
Onchocerca volvulus 0.0051 0.0025 0.0393
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0102 0.0089 0.0409
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0041 0.0012 0.0081
Schistosoma mansoni tsg101-related 0.0047 0.002 0.0019
Onchocerca volvulus 0.0174 0.018 0.294
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.0025 0.0024
Echinococcus multilocularis caspase 0.0177 0.0183 0.0181
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0074 0.0073
Echinococcus multilocularis beta LACTamase domain containing family member 0.0155 0.0155 0.0153
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0161 0.0163 0.4552
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0408 0.0475 0.0472
Loa Loa (eye worm) hypothetical protein 0.0033 0.0003 0.0001
Mycobacterium ulcerans esterase/lipase LipP 0.0155 0.0155 0.2039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0084 0.0066 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Schistosoma mansoni myst-related protein 0.0037 0.0008 0.0007
Brugia malayi hypothetical protein 0.0126 0.0119 0.0547
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0041 0.0012 0.001
Echinococcus multilocularis survival motor neuron protein 1 0.048 0.0565 0.0562
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0371 0.0428 0.0426
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0059 0.0035 0.0033
Brugia malayi Calcitonin receptor-like protein seb-1 0.0518 0.0613 0.2833
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0316 0.0358 0.5285
Onchocerca volvulus Glucosylceramidase homolog 0.0184 0.0193 0.3147
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Brugia malayi Inositol monophosphatase family protein 0.0033 0.0002 0.0006
Leishmania major regulatory subunit of protein kinase a-like protein 0.0041 0.0012 0.0272
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0205 0.3363
Schistosoma mansoni importin-beta 2 0.0047 0.002 0.0019
Loa Loa (eye worm) MH2 domain-containing protein 0.0251 0.0277 0.0836
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0316 0.0358 0.9904
Echinococcus granulosus snurportin 1 0.2638 0.3281 0.3279
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.063 0.0753 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0091 0.2531
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0043 0.0015 0.0014
Trichomonas vaginalis inositol monophosphatase, putative 0.0316 0.0358 0.5867
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0177 0.0183 0.0181
Schistosoma mansoni hypothetical protein 0.0046 0.0019 0.0018
Schistosoma mansoni cpg binding protein 0.0297 0.0335 0.0334
Loa Loa (eye worm) hypothetical protein 0.0055 0.0029 0.0082
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0294 0.0331 0.0328
Schistosoma mansoni tar DNA-binding protein 0.0198 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0126 0.0119 0.0356
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0033 0.0002 0.0039
Brugia malayi ImpB/MucB/SamB family protein 0.0066 0.0044 0.0197
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0057 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus multilocularis serotonin receptor 0.0051 0.0025 0.0023
Schistosoma mansoni microtubule-associated protein tau 0.7977 1 1
Echinococcus multilocularis orexin receptor type 2 0.0051 0.0025 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0198 0.021 0.0634
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0025 0.0023
Trichomonas vaginalis penicillin-binding protein, putative 0.0155 0.0155 0.2548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.0003 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.0193 0.3159
Brugia malayi G protein-coupled receptor 0.0051 0.0025 0.0111
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0283 0.0317 0.0961
Schistosoma mansoni metabotropic glutamate receptor 0.0126 0.0119 0.0118
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0186 0.0195 0.5407
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0003 0.0002
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0057 0.0032 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0102 0.0089 0.0088
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0041 0.0012 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0314 0.5151
Loa Loa (eye worm) hypothetical protein 0.0066 0.0044 0.0126
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0012 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Onchocerca volvulus 0.0051 0.0025 0.0393
Echinococcus multilocularis tar DNA binding protein 0.0198 0.021 0.0208
Onchocerca volvulus 0.0051 0.0025 0.0393
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0041 0.0012 0.0127
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0006 0.0101
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0988 0.1205 1
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.0193 0.3159
Entamoeba histolytica transcription factor BTF3, putative 0.0041 0.0012 0.028
Toxoplasma gondii HEAT repeat-containing protein 0.0247 0.0272 0.4004
Echinococcus multilocularis sex peptide receptor 0.0051 0.0025 0.0023
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0112 0.0102 0.2852
Loa Loa (eye worm) histone methyltransferase 0.0094 0.0079 0.0235
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0051 0.0025 0.0023
Schistosoma mansoni glutamate receptor kainate 0.0246 0.027 0.0269
Brugia malayi Receptor family ligand binding region containing protein 0.0128 0.0121 0.0557
Loa Loa (eye worm) TK/EPH protein kinase 0.0188 0.0197 0.0594
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0042 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus multilocularis allatostatin A receptor 0.0051 0.0025 0.0023
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0102 0.0089 0.1463
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0166 0.0163
Schistosoma mansoni hypothetical protein 0.0033 0.0002 0.0001
Trypanosoma cruzi protein kinase A regulatory subunit 0.0041 0.0012 0.0339
Echinococcus granulosus single minded 2 0.0141 0.0139 0.0136
Schistosoma mansoni voltage-gated potassium channel 0.0309 0.035 0.0349
Plasmodium falciparum metacaspase 1 0.0102 0.0089 0.3093
Onchocerca volvulus 0.0051 0.0025 0.0393
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.0003 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0012 0.0081
Echinococcus multilocularis GPCR, family 2 0.0164 0.0167 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0003 0.0008
Echinococcus granulosus histone lysine methyltransferase setb 0.009 0.0074 0.0071
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.001 0.0382
Echinococcus granulosus caspase 2 0.0276 0.0309 0.0306
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.0025 0.0024
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.063 0.0753 1
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0089 0.1463
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0186 0.0195 0.5438
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0091 0.2531
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0025 0.0023
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0006 0.0004
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.0025 0.0023
Schistosoma mansoni pap-inositol-14-phosphatase 0.0033 0.0002 0.0001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0155 0.0155 0.0154
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Loa Loa (eye worm) runx1 0.006 0.0037 0.0105
Echinococcus granulosus dnaJ subfamily B 0.3822 0.4771 0.477
Loa Loa (eye worm) hypothetical protein 0.0126 0.0119 0.0356
Echinococcus granulosus dna polymerase eta 0.0066 0.0044 0.0041
Echinococcus granulosus importin 5 0.0047 0.002 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0051 0.1424
Loa Loa (eye worm) hypothetical protein 0.0258 0.0286 0.0864
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0186 0.0195 0.5438
Loa Loa (eye worm) beta-lactamase 0.0155 0.0155 0.0467
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0191 0.0201 0.1649
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0012 0.0028
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0012 0.0255
Brugia malayi Pre-SET motif family protein 0.0454 0.0532 0.246
Brugia malayi mbt repeat family protein 0.0102 0.0089 0.0406
Treponema pallidum catabolite gene activator (Crp) 0.0041 0.0012 0.0032
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0012 0.0076
Brugia malayi sulfakinin receptor protein 0.0051 0.0025 0.0111
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0126 0.0119 0.0356
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0068 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0745
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0875 0.1062 0.106
Echinococcus multilocularis voltage gated potassium channel 0.0085 0.0068 0.0065
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0116 0.0106 0.0488
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0067 0.0045 0.0745
Trypanosoma cruzi cruzipain precursor, putative 0.0072 0.0051 0.1424
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0371 0.0428 0.0426
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.0166 0.0763
Mycobacterium tuberculosis Conserved protein 0.0155 0.0155 0.1273
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0161 0.0163 0.0161
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.0025 0.0069
Schistosoma mansoni tsg101-related 0.0058 0.0034 0.0033
Trypanosoma cruzi metacaspase, putative 0.0102 0.0089 0.2494
Brugia malayi hypothetical protein 0.0103 0.0091 0.0415
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0155 0.0155 0.0154
Schistosoma mansoni gabp alpha 0.0074 0.0054 0.0053
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0076 0.0057 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Schistosoma mansoni neuropeptide receptor 0.0051 0.0025 0.0024
Brugia malayi Inositol-1 0.0316 0.0358 0.1653
Schistosoma mansoni ephrin receptor 0.0148 0.0147 0.0146
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0066 0.0301
Loa Loa (eye worm) hypothetical protein 0.0116 0.0106 0.0317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Leishmania major hypothetical protein, conserved 0.0103 0.0091 0.2457
Schistosoma mansoni lamin 0.0117 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0155 0.0155 0.0467
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0033 0.0002 0.0039
Echinococcus granulosus nmda type glutamate receptor 0.2142 0.2656 0.2655
Onchocerca volvulus 0.0094 0.0079 0.1285
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Echinococcus granulosus voltage gated potassium channel 0.0085 0.0068 0.0065
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0054 0.0159
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0067 0.0045 0.0745
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0246 0.027 0.0268
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0042 0.0013 0.0164
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.0025 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0025 0.0024
Trypanosoma brucei PAB1-binding protein , putative 0.0103 0.0091 0.2531
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0102 0.0089 0.1438
Brugia malayi Glutamate receptor 1 precursor 0.0246 0.027 0.1245
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0191 0.0201 0.2642
Echinococcus multilocularis hyperpolarization activated cyclic 0.0059 0.0035 0.0033
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0155 0.0155 0.2039
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0025 0.0069
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0025 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0035 0.0034
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0116 0.0106 0.0104
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0041 0.0012 0.0081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0067 0.0045 0.0745
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0246 0.027 0.0268
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0041 0.0012 0.0145
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0281 0.0314 0.1451
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0012 0.0011
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0191 0.0201 0.0925
Echinococcus granulosus tumor susceptibility gene 101 protein 0.007 0.0048 0.0046
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Echinococcus granulosus neuropeptide s receptor 0.6385 0.7997 0.7997
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.0025 0.0023
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.0025 0.0023
Schistosoma mansoni neuropeptide receptor 0.0051 0.0025 0.0024
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Brugia malayi intermediate filament protein 0.0117 0.0109 0.0498
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0161 0.0163 0.2386
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0012 0.0009
Schistosoma mansoni zinc finger protein 0.0039 0.001 0.0009
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0006 0.0024
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0041 0.0012 0.0339
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0042 0.0013 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0025 0.0023
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0316 0.0358 1
Trypanosoma cruzi extracellular receptor, putative 0.0126 0.0119 0.333
Trypanosoma cruzi metacaspase, putative 0.0102 0.0089 0.2494
Onchocerca volvulus 0.0102 0.0089 0.1438
Loa Loa (eye worm) hypothetical protein 0.0518 0.0613 0.1862
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0316 0.0358 1
Brugia malayi beta-lactamase family protein 0.0155 0.0155 0.0715
Toxoplasma gondii LsmAD domain-containing protein 0.0103 0.0091 0.1311
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0025 0.0024
Schistosoma mansoni opsin-like receptor 0.0051 0.0025 0.0024
Echinococcus granulosus glutamate receptor subunit protein glur 0.0246 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.0276 0.0309 0.0934
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0059 0.0035 0.0034
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0298 0.0336 0.0335
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0059 0.0035 0.0578
Plasmodium falciparum metacaspase-like protein 0.0102 0.0089 0.3093
Trypanosoma cruzi metacaspase, putative 0.0102 0.0089 0.2494
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0054 0.0052
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.0025 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0051 0.1424
Plasmodium falciparum importin beta, putative 0.0247 0.0272 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0017 0.0016
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.0003 0.0002
Schistosoma mansoni caspase-7 (C14 family) 0.0276 0.0309 0.0308
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.0084 0.0384
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0016 0.0015
Loa Loa (eye worm) transcription factor SMAD2 0.0251 0.0277 0.0836
Trypanosoma brucei metacaspase 0.0102 0.0089 0.2494
Loa Loa (eye worm) hypothetical protein 0.0126 0.0119 0.0356
Loa Loa (eye worm) hypothetical protein 0.0129 0.0123 0.0368
Loa Loa (eye worm) hypothetical protein 0.0243 0.0266 0.0804
Echinococcus granulosus caspase 0.0177 0.0183 0.0181
Brugia malayi kap beta 3 protein 0.0047 0.002 0.0086
Echinococcus granulosus intermediate filament protein 0.0117 0.0109 0.0106
Echinococcus multilocularis zinc finger protein 0.0039 0.001 0.0007
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.0025 0.0111
Trichomonas vaginalis inositol monophosphatase, putative 0.0033 0.0002 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0006 0.0101
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0102 0.1673
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0069
Schistosoma mansoni opsin-like receptor 0.0051 0.0025 0.0024
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0041 0.0012 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0283 0.0317 0.0315
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0294 0.0331 0.033
Brugia malayi MAP kinase sur-1 0.0112 0.0102 0.0468
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0186 0.0195 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0297 0.0335 0.1013
Echinococcus granulosus histone acetyltransferase MYST2 0.0116 0.0106 0.0104
Mycobacterium ulcerans aldehyde dehydrogenase 0.0318 0.0361 0.4783
Echinococcus multilocularis cpg binding protein 0.0316 0.0359 0.0356
Loa Loa (eye worm) hypothetical protein 0.0525 0.0621 0.1888
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0076 0.0057 0.0056
Echinococcus granulosus g protein coupled receptor 0.0051 0.0025 0.0023
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0155 0.0155 0.0467
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0012 0.0322
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.001 0.0022
Brugia malayi hypothetical protein 0.0151 0.0151 0.0694
Trichomonas vaginalis D-aminoacylase, putative 0.0155 0.0155 0.2548
Loa Loa (eye worm) hypothetical protein 0.0033 0.0003 0.0001
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0126 0.0119 0.0356
Onchocerca volvulus 0.0051 0.0025 0.0393
Onchocerca volvulus 0.0033 0.0003 0.0027
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0025 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.0003 0.0008
Schistosoma mansoni sex comb on midleg homolog 0.0102 0.0089 0.0088
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0102 0.0089 0.1463
Schistosoma mansoni myelin transcription factor 1 myt1 0.0116 0.0106 0.0105
Leishmania major protein kinase A regulatory subunit, putative 0.0041 0.0012 0.0272
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0025 0.0023
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Echinococcus multilocularis caspase 8 0.0102 0.0089 0.0087
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0051 0.1424
Trichomonas vaginalis hypothetical protein 0.0036 0.0006 0.0101
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0025 0.0023
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0025 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0012 0.0322
Echinococcus multilocularis caspase 2 0.0276 0.0309 0.0306
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.0003 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0025 0.0069
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.0025 0.0069
Entamoeba histolytica HEAT repeat domain containing protein 0.0047 0.002 0.0483
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0025 0.0069
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.0025 0.0023
Brugia malayi hypothetical protein 0.0051 0.0025 0.0111
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0006 0.0107
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0043 0.1205
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0025 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.0193 0.3159
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0161 0.0163 0.049
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0177 0.0183 0.0181
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0059 0.0035 0.0033
Loa Loa (eye worm) kap beta 3 protein 0.0047 0.002 0.0052
Trypanosoma cruzi transcription factor btf3, putative 0.0041 0.0012 0.0345
Echinococcus multilocularis ephrin type A receptor 4 A 0.0148 0.0147 0.0144
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0112 0.0102 0.2777
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0012 0.0196

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 260 uM PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493224] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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