Detailed information for compound 78692

Basic information

Technical information
  • TDR Targets ID: 78692
  • Name: 4-[4-(2-chlorophenyl)piperazin-1-yl]-1-phenox ybutan-2-ol
  • MW: 360.878 | Formula: C20H25ClN2O2
  • H donors: 1 H acceptors: 1 LogP: 3.89 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(COc1ccccc1)CCN1CCN(CC1)c1ccccc1Cl
  • InChi: 1S/C20H25ClN2O2/c21-19-8-4-5-9-20(19)23-14-12-22(13-15-23)11-10-17(24)16-25-18-6-2-1-3-7-18/h1-9,17,24H,10-16H2
  • InChiKey: QWIATLITSFZWRE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[4-(2-chlorophenyl)piperazin-1-yl]-1-phenoxy-butan-2-ol
  • 4-[4-(2-chlorophenyl)-1-piperazinyl]-1-phenoxy-2-butanol
  • 4-[4-(2-chlorophenyl)piperazino]-1-phenoxy-butan-2-ol
  • 4-[4-(2-chlorophenyl)piperazin-1-yl]-1-(phenoxy)butan-2-ol
  • 4-[4-(2-chlorophenyl)-1-piperazinyl]-1-(phenoxy)butan-2-ol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.002 0.0115 0.0109
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0014 0.0045 0.0036
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0172 0.0169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Loa Loa (eye worm) hypothetical protein 0.0032 0.0267 0.0279
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0032 0.0267 0.0238
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0083 0.0087
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0012 0.001 0.0011
Schistosoma mansoni hypothetical protein 0.0414 0.4979 0.5208
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0318 0.0322
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.007 0.0737 0.0737
Schistosoma mansoni thyroid hormone receptor 0.002 0.0117 0.0123
Brugia malayi G-protein coupled receptor 0.007 0.0737 0.077
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0117 0.0123
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Schistosoma mansoni equilibrative nucleoside transporter 0.0014 0.0045 0.0047
Schistosoma mansoni lamin 0.0027 0.0205 0.0215
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0012 0.001 0.0011
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0249 0.0249
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0267 0.0269
Loa Loa (eye worm) AMP deaminase 0.0309 0.3682 0.3851
Echinococcus multilocularis expressed protein 0.0378 0.4532 0.4532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Loa Loa (eye worm) phosphatidylinositol 3 0.0219 0.2572 0.269
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0123
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.007 0.0737 0.0737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Trypanosoma cruzi GMP synthase [glutamine-hydrolysing] 0.0044 0.0415 0.0424
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0032 0.0267 0.0238
Echinococcus multilocularis Ankyrin 0.0015 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0045 0.0047
Brugia malayi Egg laying defective protein 4 0.0012 0.002 0.0021
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0309 0.3682 0.3845
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.041 0.0429
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0012 0.001 0.0011
Onchocerca volvulus 0.0049 0.0471 0.1254
Echinococcus granulosus cGMP dependent protein kinase 1 0.0012 0.002 0.0021
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0012 0.002 0.002
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0032 0.0267 0.0269
Onchocerca volvulus 0.007 0.0737 0.1978
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.044 0.046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0083 0.0087
Loa Loa (eye worm) hypothetical protein 0.0025 0.0172 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0737 0.0737
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0045 0.0036
Brugia malayi G protein-coupled receptor F59B2.13 0.007 0.0737 0.077
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.007 0.0737 0.077
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0267 0.0279
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0137 0.1564 0.1626
Brugia malayi larval opioid receptor 0.007 0.0737 0.077
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0014 0.0045 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0117 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0737 0.077
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0108 0.0113
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0031 0.0031
Entamoeba histolytica hypothetical protein 0.0019 0.0108 0.0071
Brugia malayi hypothetical protein 0.0082 0.0885 0.0926
Onchocerca volvulus 0.0156 0.1795 0.4862
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0785 0.9561 1
Echinococcus granulosus serine protein kinase ATM 0.0032 0.0267 0.0279
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.007 0.0737 0.0737
Schistosoma mansoni adenosylhomocysteinase 0.0486 0.5866 0.6136
Mycobacterium tuberculosis Probable GMP synthase [glutamine-hydrolyzing] GuaA (glutamine amidotransferase) (GMP synthetase) 0.0022 0.0145 0.0141
Brugia malayi hypothetical protein 0.0014 0.0045 0.0047
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Echinococcus multilocularis alpha 1A adrenergic receptor 0.007 0.0737 0.0737
Entamoeba histolytica hypothetical protein 0.0032 0.0267 0.0238
Echinococcus multilocularis neuropeptide receptor A26 0.007 0.0737 0.0737
Loa Loa (eye worm) hypothetical protein 0.0013 0.0031 0.0032
Brugia malayi Serotonin receptor 0.007 0.0737 0.077
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0509 0.0522
Echinococcus granulosus solute carrier family 28 0.0348 0.4162 0.4353
Leishmania major phosphatidylinositol 4-kinase, putative 0.0057 0.0569 0.0585
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Entamoeba histolytica hypothetical protein 0.0032 0.0267 0.0238
Echinococcus multilocularis serotonin receptor 0.007 0.0737 0.0737
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0014 0.004 0.0031
Trypanosoma cruzi nucleobase transporter, putative 0.0014 0.0045 0.0036
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0045 0.0036
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0069 0.0715 0.0747
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0012 0.0022 0.0012
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0012 0.001 0.0011
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0045 0.0036
Trypanosoma cruzi AMP deaminase 2, putative 0.011 0.1228 0.1275
Trichomonas vaginalis ribokinase, putative 0.002 0.0116 0.0111
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0123
Trypanosoma cruzi GMP synthase, putative 0.002 0.0116 0.0111
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0032 0.0267 0.0269
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.2823 0.2823
Entamoeba histolytica adenosylhomocysteinase, putative 0.0785 0.9561 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0108 0.0113
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0117 0.0123
Trypanosoma cruzi nucleobase transporter, putative 0.0014 0.0045 0.0036
Echinococcus granulosus geminin 0.0172 0.1986 0.2077
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0032 0.0267 0.1651
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0032 0.0267 0.0269
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0059 0.005
Brugia malayi hypothetical protein 0.0019 0.0108 0.0113
Trichomonas vaginalis ran, putative 0.0021 0.0134 0.0129
Schistosoma mansoni ran 0.0021 0.0134 0.014
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0041 0.0041
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0083 0.0083
Brugia malayi PXA domain containing protein 0.0019 0.0108 0.0113
Trypanosoma brucei purine nucleoside transporter 0.0014 0.0045 0.0036
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0052 0.0513 0.0527
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.0039 0.0347 0.0363
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0318 0.0322
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0026 0.0017
Echinococcus granulosus flap endonuclease 1 0.0026 0.0194 0.0203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Onchocerca volvulus 0.0027 0.0205 0.0531
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.009 0.0978 0.623
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0267 0.0269
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0052 0.0513 0.0527
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0041 0.0032
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0219 0.2572 0.269
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0267 0.0269
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0318 0.0322
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0032 0.0267 0.0267
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0318 0.0322
Schistosoma mansoni hypothetical protein 0.0012 0.001 0.0011
Leishmania major putative PfkB family sugar kinase 0.002 0.0116 0.0111
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Schistosoma mansoni biogenic amine receptor 0.007 0.0737 0.077
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0134 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0737 0.077
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0059 0.0596 0.0613
Trypanosoma cruzi adenosine kinase, putative 0.0176 0.2043 0.2129
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Brugia malayi prolyl oligopeptidase family protein 0.0059 0.0596 0.0624
Brugia malayi sulfakinin receptor protein 0.007 0.0737 0.077
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0134 0.014
Trypanosoma brucei nucleoside transporter 1, putative 0.0014 0.0045 0.0036
Leishmania major hypothetical protein, conserved 0.0025 0.0172 0.0169
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.011 0.1228 0.1275
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0026 0.0017
Echinococcus granulosus Dipeptidyl peptidase 9 0.0059 0.0596 0.0624
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.002 0.0116 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0011
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0117 0.0123
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0069 0.0715 0.0709
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Schistosoma mansoni hypothetical protein 0.0312 0.3714 0.3885
Echinococcus granulosus g-protein coupled receptor 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Echinococcus granulosus adenosine kinase 0.0176 0.2043 0.2137
Echinococcus multilocularis AMP deaminase 2 0.0309 0.3682 0.3682
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0095 0.1038 0.1086
Onchocerca volvulus 0.011 0.1228 0.3316
Brugia malayi Cytochrome P450 family protein 0.0012 0.0022 0.0023
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0134 0.0129
Onchocerca volvulus 0.0036 0.0318 0.0838
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0022 0.0023
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0118 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0117 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0117 0.0123
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0108 0.0113
Loa Loa (eye worm) hypothetical protein 0.009 0.0979 0.1024
Schistosoma mansoni neuropeptide F-like receptor 0.007 0.0737 0.077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0117 0.0123
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.009 0.0978 0.1013
Leishmania major adenosine kinase-like protein 0.002 0.0116 0.0111
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0219 0.2572 0.2572
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0052 0.0513 0.0513
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0309 0.3682 0.3845
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0022 0.0012
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0049 0.0051
Brugia malayi follicle stimulating hormone receptor 0.007 0.0737 0.077
Brugia malayi steroid hormone receptor 0.002 0.0117 0.0123
Entamoeba histolytica hypothetical protein 0.0024 0.0161 0.0127
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0123
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0059 0.0596 0.0596
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0026 0.0017
Echinococcus granulosus sodium:glucose cotransporter 2 0.0039 0.0347 0.0363
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.011 0.1228 0.1275
Echinococcus granulosus expressed protein 0.0378 0.4532 0.474
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0249 0.0261
Schistosoma mansoni ran 0.0021 0.0134 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0737 0.077
Toxoplasma gondii kinase, pfkB family protein 0.002 0.0116 0.0111
Echinococcus multilocularis g-protein coupled receptor 0.007 0.0737 0.0737
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0117 0.0123
Leishmania major adenosine kinase-like protein 0.002 0.0116 0.0111
Giardia lamblia Hypothetical protein 0.0082 0.0885 0.5631
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0032 0.0267 0.0269
Echinococcus granulosus thyrotropin releasing hormone receptor 0.007 0.0737 0.077
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0108 0.0113
Plasmodium vivax hypothetical protein, conserved 0.0014 0.004 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0789 0.0789
Leishmania major adenosine kinase, putative 0.0176 0.2043 0.2129
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0017 0.0081 0.0081
Echinococcus granulosus lamin dm0 0.0027 0.0205 0.0215
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0117 0.0123
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0117 0.0123
Leishmania major GTP-binding protein, putative 0.0021 0.0134 0.0129
Schistosoma mansoni alpha-1 adrenergic receptor 0.007 0.0737 0.077
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.011 0.1228 0.1275
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0016 0.0072 0.0064
Mycobacterium tuberculosis Conserved protein 0.0036 0.0318 0.0322
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0113
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0095 0.1038 0.1086
Loa Loa (eye worm) G-protein coupled receptor 0.007 0.0737 0.077
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0017 0.0081 0.0085
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0012 0.002 0.001
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0108 0.0113
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0134 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0117 0.0123
Echinococcus granulosus fmrfamide receptor 0.007 0.0737 0.077
Onchocerca volvulus 0.007 0.0737 0.1978
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0045 0.0036
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0069 0.0715 0.0737
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.004 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0123
Onchocerca volvulus 0.007 0.0737 0.1978
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) prolyl oligopeptidase 0.0014 0.004 0.0042
Toxoplasma gondii nucleoside transporter protein 0.0014 0.0045 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0117 0.0117
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0045 0.0036
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0137 0.1564 0.1635
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0039 0.0347 0.0347
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0012 0.001 0.0011
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0026 0.0017
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.011 0.1228 0.1275
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0111
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0032 0.0267 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Schistosoma mansoni cpg binding protein 0.0029 0.0227 0.0238
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0032 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0249 0.0261
Echinococcus multilocularis prolyl endopeptidase 0.0014 0.004 0.004
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0219 0.2572 0.269
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0041 0.0043
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0509 0.0522
Brugia malayi hypothetical protein 0.0239 0.2823 0.2953
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Schistosoma mansoni importin beta-1 0.0029 0.0229 0.0239
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0083 0.0087
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0041 0.0043
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0309 0.3682 0.3845
Echinococcus multilocularis sodium:nucleoside cotransporter 2 0.0227 0.2669 0.2669
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0017 0.0083 0.0087
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.009 0.0979 0.1024
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0004 0.0005
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0014 0.004 0.0042
Schistosoma mansoni amine GPCR 0.007 0.0737 0.077
Loa Loa (eye worm) G-protein coupled receptor 0.007 0.0737 0.077
Entamoeba histolytica DNA repair and recombination protein, putative 0.0028 0.0211 0.0179
Schistosoma mansoni survival motor neuron protein 0.0049 0.0471 0.0493
Schistosoma mansoni coup transcription factor 0.002 0.0117 0.0123
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0194 0.1181
Trypanosoma brucei nucleoside transporter 1, putative 0.0014 0.0045 0.0036
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.007 0.0737 0.077
Trypanosoma brucei oligopeptidase b 0.0014 0.004 0.0031
Schistosoma mansoni neuropeptide receptor 0.007 0.0737 0.077
Echinococcus granulosus neuropeptides capa receptor 0.007 0.0737 0.077
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0043 0.0394 0.0401
Entamoeba histolytica AMP deaminase, putative 0.0309 0.3682 0.3825
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0108 0.0102
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0016 0.007 0.0062
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0476 0.0498
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0073
Mycobacterium leprae Possible regulatory protein 0.0013 0.0026 0.0017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0267 0.0279
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0061 0.0619 0.0637
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0014 0.0041 0.0041
Brugia malayi beta-lactamase family protein 0.0036 0.0318 0.0333
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0014 0.004 0.0031
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0032 0.0267 0.0269
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0108 0.0113
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0059 0.0596 0.0613
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0219 0.2572 0.269
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0118 0.0123
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.038 0.0387
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0026 0.0026
Toxoplasma gondii adenosylhomocysteinase, putative 0.0785 0.9561 1
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.005 0.0052
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.007 0.0737 0.0737
Mycobacterium ulcerans GMP synthase 0.0061 0.0619 0.0637
Trypanosoma cruzi adenosine kinase, putative 0.002 0.0116 0.0111
Schistosoma mansoni neuropeptide f receptor 76f 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.0352 0.4211 0.4405
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0014 0.004 0.0031
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.009 0.0979 0.1024
Brugia malayi hypothetical protein 0.0123 0.1389 0.1453
Trypanosoma cruzi AMP deaminase, putative 0.0309 0.3682 0.3845
Onchocerca volvulus 0.0219 0.2572 0.6976
Trypanosoma brucei AMP deaminase, putative 0.0309 0.3682 0.3845
Mycobacterium ulcerans NAD synthetase 0.0016 0.0072 0.0064
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0118 0.0123
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0219 0.2572 0.269
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0014 0.004 0.0042
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Plasmodium falciparum peptidase, putative 0.0014 0.004 0.0031
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0059 0.005
Plasmodium falciparum flap endonuclease 1 0.0026 0.0194 0.0192
Plasmodium falciparum importin beta, putative 0.0029 0.0229 0.0229
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0014 0.004 0.0031
Schistosoma mansoni hypothetical protein 0.0028 0.0211 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.004 0.0031
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0045 0.0036
Entamoeba histolytica nucleoside transporter, putative 0.0014 0.0045 0.0005
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.009 0.0979 0.1024
Trypanosoma cruzi AMP deaminase, putative 0.0309 0.3682 0.3845
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0061 0.0619 0.0637
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0117 0.0123
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.007 0.0737 0.077
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0117 0.0123
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0048 0.005
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0137 0.1564 0.1626
Loa Loa (eye worm) phosphatidylinositol 3 0.0057 0.0569 0.0595
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0045 0.0036
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0309 0.3682 0.3845
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0041 0.0041
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0513 0.0537
Echinococcus multilocularis microtubule associated protein 2 0.0699 0.849 0.849
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0059 0.0596 0.0613
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0041 0.0043
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0077 0.0815 0.0843
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0509 0.0509
Leishmania major ribokinase, putative 0.002 0.0116 0.0111
Onchocerca volvulus Putative pyridoxal kinase 0.002 0.0116 0.0288
Brugia malayi hypothetical protein 0.0045 0.0425 0.0444
Plasmodium falciparum adenosine deaminase 0.011 0.1228 0.1275
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0161 0.0157
Schistosoma mansoni hypothetical protein 0.0032 0.0267 0.0279
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.007 0.0737 0.077
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0052 0.0513 0.0527
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0509 0.0532
Schistosoma mansoni nuclear hormone receptor 0.002 0.0117 0.0123
Toxoplasma gondii kinase, pfkB family protein 0.0176 0.2043 0.2129
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0737 0.0737
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0117 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0737 0.0737
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0194 0.0192
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0117 0.0123
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.007 0.0737 0.077
Treponema pallidum adenosine deaminase 0.011 0.1228 0.784
Leishmania major importin beta-1 subunit, putative 0.0024 0.0161 0.0157
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.009 0.0979 0.1014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0737 0.077
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0059 0.005
Loa Loa (eye worm) hypothetical protein 0.004 0.0361 0.0377
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0014 0.004 0.0031
Brugia malayi hypothetical protein 0.002 0.0116 0.0122
Brugia malayi hypothetical protein 0.0124 0.1399 0.1463
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0041 0.0043
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.038 0.0387
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0513 0.0537
Echinococcus granulosus death domain containing protein 0.0015 0.0048 0.005
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0032 0.0267 0.0238
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.2742 0.2861
Echinococcus granulosus alpha 1A adrenergic receptor 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.0199 0.2322 0.2429
Schistosoma mansoni hypothetical protein 0.0052 0.0515 0.0538
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0108 0.0108
Echinococcus granulosus patatin phospholipase domain containing protein 0.0012 0.001 0.0011
Toxoplasma gondii FATC domain-containing protein 0.0032 0.0267 0.0269
Echinococcus granulosus tm gpcr rhodopsin 0.007 0.0737 0.077
Echinococcus multilocularis biogenic amine (5HT) receptor 0.007 0.0737 0.0737
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0032 0.0267 0.0279
Loa Loa (eye worm) hypothetical protein 0.0013 0.0025 0.0026
Onchocerca volvulus 0.007 0.0737 0.1978
Plasmodium vivax importin-beta 2, putative 0.0029 0.0229 0.0229
Echinococcus multilocularis fmrfamide receptor 0.007 0.0737 0.0737
Brugia malayi CXXC zinc finger family protein 0.0029 0.0227 0.0238
Brugia malayi hypothetical protein 0.0036 0.0313 0.0328
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0069 0.0715 0.0737
Onchocerca volvulus 0.007 0.0737 0.1978
Schistosoma mansoni opsin-like receptor 0.007 0.0737 0.077
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0052 0.0513 0.0497
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.007 0.0737 0.077
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0052 0.0513 0.0527
Onchocerca volvulus 0.007 0.0737 0.1978
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0057 0.0569 0.0595
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0194 0.0203
Trypanosoma brucei unspecified product 0.0014 0.0045 0.0036
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0032 0.0267 0.0279
Leishmania major hypothetical protein, conserved 0.0036 0.0318 0.0322
Echinococcus granulosus importin subunit beta 1 0.0029 0.0229 0.0239
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0737 0.077
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0032 0.0267 0.0267
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1305 0.1365
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0789 0.0825
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0785 0.9561 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0052 0.0513 0.0527
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0036 0.0027
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0045 0.0036
Echinococcus multilocularis adenosine deaminase 0.011 0.1228 0.1228
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0043 0.0394 0.0401
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0509 0.0522
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0117 0.0123
Loa Loa (eye worm) hypothetical protein 0.0052 0.0513 0.0537
Loa Loa (eye worm) hypothetical protein 0.0013 0.0025 0.0026
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0513 0.0537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0032 0.0267 0.0279
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0032 0.0267 0.0269
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0032 0.0267 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0785 0.9561 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0117 0.0123
Schistosoma mansoni adenosine kinase 0.0176 0.2043 0.2137
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Schistosoma mansoni peptide (allatostatin)-like receptor 0.007 0.0737 0.077
Brugia malayi hypothetical protein 0.0016 0.0064 0.0067
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0016 0.0072 0.0064
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0026 0.0017
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0117 0.0123
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0059 0.0061
Echinococcus granulosus solute carrier family 5 0.0039 0.0347 0.0363
Echinococcus multilocularis g protein coupled receptor 0.007 0.0737 0.0737
Loa Loa (eye worm) hypothetical protein 0.0045 0.0425 0.0444
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0118 0.0123
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0028 0.0211 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0012 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0123
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0137 0.1564 0.1635
Loa Loa (eye worm) hypothetical protein 0.011 0.1228 0.1285
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0123
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.044 0.046
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0082 0.0885 0.0885
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0069 0.0715 0.0737
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0041 0.0043
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0318 0.0322
Onchocerca volvulus 0.007 0.0737 0.1978
Brugia malayi STAT protein, DNA binding domain containing protein 0.0133 0.1512 0.1581
Brugia malayi ecdysteroid receptor 0.002 0.0117 0.0123
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0052 0.0513 0.0527
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0318 0.0322
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0052 0.0513 0.0527
Onchocerca volvulus 0.007 0.0737 0.1978
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0032 0.0267 0.0269
Echinococcus granulosus adenosine deaminase 0.011 0.1228 0.1285
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0267 0.0279
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0057 0.0569 0.0585
Onchocerca volvulus Neuropeptide F receptor homolog 0.007 0.0737 0.1978
Echinococcus multilocularis snurportin 1 0.0312 0.3714 0.3714
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0219 0.2572 0.2572
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0026 0.0017
Echinococcus granulosus 7tm_1 domain containing protein 0.007 0.0737 0.077
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0039 0.0347 0.0363
Loa Loa (eye worm) hypothetical protein 0.0165 0.1908 0.1995
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0032 0.0267 0.0269
Echinococcus multilocularis orexin receptor type 2 0.007 0.0737 0.0737
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0059 0.0059
Brugia malayi Uncoordinated protein 44 0.0015 0.0048 0.005
Mycobacterium ulcerans beta-lactamase 0.0036 0.0318 0.0322
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.004 0.0031
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.007 0.0737 0.0737
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.001 0.0011
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0267 0.0269
Mycobacterium ulcerans carbohydrate kinase CbhK 0.002 0.0116 0.0111
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0137 0.1564 1
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0045 0.0036
Schistosoma mansoni cpg binding protein 0.0031 0.0248 0.0259
Giardia lamblia Phosphatidylinositol 4-kinase 0.0057 0.0569 0.3596
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0117 0.0123
Leishmania major cytochrome p450-like protein 0.0012 0.0022 0.0012
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0137 0.1564 0.1564
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0014 0.004 0.0031
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0137 0.1564 1
Onchocerca volvulus Adenosine deaminase homolog 0.011 0.1228 0.3316
Brugia malayi AKH receptor 0.007 0.0737 0.077
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0134 0.0129
Echinococcus multilocularis allatostatin A receptor 0.007 0.0737 0.0737
Onchocerca volvulus 0.007 0.0737 0.1978
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0059 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0014 0.0045 0.0036
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.007 0.0737 0.077
Echinococcus granulosus neuropeptide receptor A26 0.007 0.0737 0.077
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.004 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0249 0.0261
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0161 0.0157
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0041 0.0043
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0175 0.2033 0.2127
Loa Loa (eye worm) hypothetical protein 0.0321 0.3832 0.4008
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0052 0.0513 0.0497
Brugia malayi RE15519p 0.007 0.0737 0.077
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0137 0.1564 0.1626
Echinococcus multilocularis g protein coupled receptor 0.007 0.0737 0.0737
Loa Loa (eye worm) phosphatidylinositol 3 0.0219 0.2572 0.269
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0108 0.0113
Giardia lamblia GTOR 0.0032 0.0267 0.1651
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus granulosus orexin receptor type 2 0.007 0.0737 0.077
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0049 0.0468 0.0479
Loa Loa (eye worm) hypothetical protein 0.0015 0.005 0.0052
Schistosoma mansoni hypothetical protein 0.0011 0.0004 0.0005
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0057 0.0569 0.0585
Trypanosoma cruzi nucleoside transporter-like, putative 0.0014 0.0045 0.0036
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.001 0.0011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0228 0.0238
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0211 0.0179
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0108 0.0108
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus multilocularis neuropeptide receptor 0.007 0.0737 0.0737
Echinococcus granulosus ribokinase 0.002 0.0116 0.0122
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0643 0.0673
Schistosoma mansoni GMP synthetase 0.0061 0.0619 0.0647
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0194 0.0192
Loa Loa (eye worm) hypothetical protein 0.0036 0.0318 0.0333
Schistosoma mansoni neuropeptide receptor 0.007 0.0737 0.077
Brugia malayi Melatonin receptor type 1A 0.007 0.0737 0.077
Brugia malayi Tachykinin-like peptides receptor 99D 0.007 0.0737 0.077
Trypanosoma brucei adenosine transporter, putative 0.0014 0.0045 0.0036
Leishmania major tagatose-6-phosphate kinase-like protein 0.002 0.0116 0.0111
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.002 0.0115 0.0079
Echinococcus multilocularis g protein coupled receptor 0.007 0.0737 0.0737
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0737 0.077
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0108 0.0113
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0039 0.0347 0.0347
Giardia lamblia Hypothetical protein 0.0032 0.0267 0.1651
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0318 0.0318
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0059 0.005
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0134 0.0134
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0229 0.0229
Trypanosoma brucei unspecified product 0.0014 0.0045 0.0036
Echinococcus granulosus cpg binding protein 0.0031 0.0248 0.0259
Schistosoma mansoni hypothetical protein 0.004 0.0361 0.0377
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0194 0.0194
Onchocerca volvulus AMP deaminase 2 homolog 0.0309 0.3682 1
Echinococcus granulosus snurportin 1 0.0312 0.3714 0.3885
Trypanosoma brucei adenosine kinase, putative 0.0176 0.2043 0.2129
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0318 0.0322
Toxoplasma gondii AMP deaminase 0.0309 0.3682 0.3845
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0036 0.0318 0.0333
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0117 0.0123
Trypanosoma brucei purine nucleoside transporter 0.0014 0.0045 0.0036
Brugia malayi GnHR receptor homolog 0.007 0.0737 0.077
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0249 0.025
Schistosoma mansoni neuropeptide receptor 0.007 0.0737 0.077
Entamoeba histolytica AMP deaminase, putative 0.0309 0.3682 0.3825
Toxoplasma gondii prolyl endopeptidase 0.0014 0.004 0.0031
Echinococcus granulosus biogenic amine 5HT receptor 0.007 0.0737 0.077
Schistosoma mansoni opsin-like receptor 0.007 0.0737 0.077
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0134 0.014
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0267 0.0269
Echinococcus granulosus neuropeptide receptor 0.007 0.0737 0.077
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0509 0.0522
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0052 0.0513 0.0537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.007 0.0737 0.077
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0059 0.0061
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0205 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0117 0.0123
Schistosoma mansoni adenosine kinase 0.0176 0.2043 0.2137
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0785 0.9561 1
Schistosoma mansoni high-affinity choline transporter 0.0352 0.4211 0.4405
Onchocerca volvulus 0.007 0.0737 0.1978
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0137 0.1564 0.1626
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0318 0.0333
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0137 0.1564 0.1626
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Entamoeba histolytica nucleoside transporter, putative 0.0082 0.0885 0.0888
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0318 0.0322
Trypanosoma cruzi ribokinase, putative 0.002 0.0116 0.0111
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.0082 0.0885 0.0926
Plasmodium falciparum cGMP-dependent protein kinase 0.0012 0.002 0.001
Entamoeba histolytica Ran family GTPase 0.0021 0.0134 0.0098
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0137 0.1564 0.1564
Onchocerca volvulus 0.0219 0.2572 0.6976
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0137 0.1564 0.1635
Onchocerca volvulus 0.0036 0.0318 0.0838
Brugia malayi Cyclic-nucleotide gated cation channel 0.0014 0.0041 0.0043
Brugia malayi putative neuropeptide receptor 0.007 0.0737 0.077
Trypanosoma cruzi nucleoside transporter 1, putative 0.0014 0.0045 0.0036
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Brugia malayi beta-lactamase family protein 0.0036 0.0318 0.0333
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0229 0.0229
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0028 0.0211 0.021
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0045 0.0036
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0361 0.0377
Echinococcus granulosus g protein coupled receptor 0.007 0.0737 0.077
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0052 0.0513 0.0527
Plasmodium falciparum adenosylhomocysteinase 0.0785 0.9561 1
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.002 0.0021
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0194 0.0162
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0108 0.0108
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0082 0.0885 0.0916
Schistosoma mansoni intermediate filament proteins 0.0027 0.0205 0.0215
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0082 0.0885 0.0916
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0172 0.0169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Brugia malayi hypothetical protein 0.0025 0.0172 0.018
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.005
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0108 0.0113
Echinococcus granulosus dnaJ subfamily B 0.0414 0.4979 0.5208
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0061 0.0619 0.0637
Toxoplasma gondii ABC1 family protein 0.0036 0.0318 0.0322
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0052 0.0513 0.0513
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.004 0.0361 0.0367
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0017 0.0081 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0108 0.0102
Entamoeba histolytica nucleoside transporter, putative 0.0014 0.0045 0.0005
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0137 0.1564 0.1635
Leishmania major adenine aminohydrolase 0.011 0.1228 0.1275
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Mycobacterium leprae conserved hypothetical protein 0.0032 0.0267 0.0269
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0118 0.0123
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Schistosoma mansoni biogenic amine receptor 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.0061 0.0619 0.0647
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0014 0.004 0.0031
Giardia lamblia Ribokinase 0.002 0.0116 0.0681
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0028 0.0211 0.021
Brugia malayi Dopamine receptor protein 2 0.007 0.0737 0.077
Echinococcus multilocularis neuropeptides capa receptor 0.007 0.0737 0.0737
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0052 0.0513 0.0527
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0194 0.0192
Mycobacterium tuberculosis Adenosine kinase 0.002 0.0116 0.0111
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0026 0.0017
Loa Loa (eye worm) hypothetical protein 0.0124 0.1399 0.1463
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0194 0.0192
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0059 0.0596 0.0613
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0014 0.004 0.0042
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0267 0.0269
Echinococcus multilocularis high affinity choline transporter 1 0.0352 0.4211 0.4211
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0028 0.0211 0.021
Onchocerca volvulus 0.007 0.0737 0.1978
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0059 0.0059
Brugia malayi G-protein coupled receptor 0.007 0.0737 0.077
Leishmania major oligopeptidase b 0.0014 0.004 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0113
Schistosoma mansoni myosin xvIII 0.007 0.0737 0.077
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0175 0.2033 0.2033
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0026 0.0017
Onchocerca volvulus 0.007 0.0737 0.1978
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0161 0.0157
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0014 0.0041 0.0043
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0014 0.004 0.0031
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0509 0.0522
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0059 0.005
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0134 0.0793
Brugia malayi PAS domain containing protein 0.0049 0.0476 0.0498
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0137 0.1564 1
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0785 0.9561 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0361 0.0377
Loa Loa (eye worm) hypothetical protein 0.0082 0.0885 0.0926
Trypanosoma brucei NAD+ synthase, putative 0.0016 0.0072 0.0064
Brugia malayi ORL1-like opioid receptor 0.007 0.0737 0.077
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0737 0.077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Schistosoma mansoni sodium/solute symporter 0.0039 0.0347 0.0363
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0737 0.077
Trypanosoma cruzi nucleoside transporter 1, putative 0.0014 0.0045 0.0036
Onchocerca volvulus 0.0029 0.0227 0.059
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0052 0.0513 0.0537
Echinococcus multilocularis dro:myosuppressin receptor 0.007 0.0737 0.0737
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.044 0.046
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0509 0.0522
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0044 0.041 0.0429
Echinococcus multilocularis dnaJ subfamily B 0.0414 0.4979 0.4979
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.2823 0.2953
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0737 0.077
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.0042
Schistosoma mansoni hypothetical protein 0.0049 0.0471 0.0493
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0108 0.0108
Plasmodium vivax adenosine/AMP deaminase, putative 0.0309 0.3682 0.3845
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0069 0.0715 0.0747
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0318 0.0322
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0011
Mycobacterium tuberculosis Ribokinase RbsK 0.002 0.0116 0.0111
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0113
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0108 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Brugia malayi nuclear hormone receptor 0.002 0.0117 0.0123
Schistosoma mansoni hypothetical protein 0.0015 0.0048 0.005
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0137 0.1564 0.1626
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.009 0.0978 0.1013
Onchocerca volvulus 0.0031 0.0249 0.065
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0028 0.0211 0.021
Trichomonas vaginalis esterase, putative 0.0036 0.0318 0.0322
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.175 0.183
Echinococcus granulosus intermediate filament protein 0.0027 0.0205 0.0215
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.009 0.0978 0.1013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0229 0.0239
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0028 0.0211 0.0211
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0361 0.0361
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0172 0.0169
Entamoeba histolytica ribokinase, putative 0.002 0.0116 0.008
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Brugia malayi GH02984p 0.0352 0.4211 0.4405
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0108 0.0102
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.004 0.0042
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0318 0.0322
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.007 0.0737 0.0737
Trypanosoma brucei adenosine transporter, putative 0.0014 0.0045 0.0036
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0017 0.0081 0.0081
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0117 0.0123
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0249 0.0249
Trypanosoma cruzi AMP deaminase, putative 0.0309 0.3682 0.3845
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.0027 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.011 0.1228 0.1285
Giardia lamblia Alanyl dipeptidyl peptidase 0.0014 0.004 0.019
Echinococcus multilocularis geminin 0.0172 0.1986 0.1986
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0082 0.0885 0.0916
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0108 0.0113
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0117 0.0123
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0318 0.0333
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0117 0.0123
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0048 0.005
Echinococcus granulosus G protein coupled receptor 139 0.007 0.0737 0.077
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0069 0.0715 0.0737
Echinococcus granulosus FTZ F1 alpha 0.002 0.0117 0.0123
Echinococcus granulosus biogenic amine 5HT receptor 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0108 0.0113
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0785 0.9561 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0562 0.0577
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0052 0.0513 0.0537
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0318 0.0322
Loa Loa (eye worm) hypothetical protein 0.0036 0.0318 0.0333
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0073
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0267 0.0279
Loa Loa (eye worm) follicle stimulating hormone receptor 0.007 0.0737 0.077
Trypanosoma cruzi oligopeptidase b 0.0014 0.004 0.0031
Echinococcus granulosus acylamino acid releasing enzyme 0.0014 0.004 0.0042
Echinococcus multilocularis neuropeptide s receptor 0.007 0.0737 0.0737
Schistosoma mansoni microtubule-associated protein tau 0.0699 0.849 0.8881
Schistosoma mansoni adenosine deaminase-related 0.011 0.1228 0.1285
Schistosoma mansoni hypothetical protein 0.0172 0.1986 0.2077
Echinococcus granulosus concentrative Na nucleoside cotransporter 0.0348 0.4162 0.4353
Schistosoma mansoni inositol transporter 0.0039 0.0347 0.0363
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0737 0.077
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0012 0.001 0.0011
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0059 0.005
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0083 0.0087
Brugia malayi Importin beta-1 subunit 0.0029 0.0229 0.0239
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0108 0.0113
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.009 0.0979 0.1014
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0318 0.0322
Schistosoma mansoni netrin receptor unc5 0.0015 0.0048 0.005
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0205 0.0215
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0219 0.2572 0.269
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0032 0.0267 0.0238
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0194 0.0192
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.044 0.044
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.007 0.0737 0.077
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0032 0.0267 0.0269
Loa Loa (eye worm) hypothetical protein 0.0124 0.1399 0.1463
Leishmania major nucleobase transporter 0.0014 0.0045 0.0036
Mycobacterium leprae Probable adenosine kinase adk 0.002 0.0116 0.0111
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0017 0.0081 0.0085
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.007 0.0737 0.0737
Schistosoma mansoni adenosine deaminase 0.011 0.1228 0.1285
Trypanosoma cruzi AMP deaminase, putative 0.0309 0.3682 0.3845
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0361 0.0367
Schistosoma mansoni biogenic amine (5HT) receptor 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.0032 0.0268 0.0281
Schistosoma mansoni amine GPCR 0.007 0.0737 0.077
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0026 0.0028
Echinococcus granulosus cGMP dependent protein kinase 1 0.0012 0.002 0.0021
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0318 0.0322
Loa Loa (eye worm) hypothetical protein 0.0219 0.2572 0.269
Trypanosoma cruzi target of rapamycin kinase 3 0.0032 0.0267 0.0269
Brugia malayi MAP kinase sur-1 0.0052 0.0509 0.0532
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Onchocerca volvulus 0.007 0.0737 0.1978
Echinococcus multilocularis serotonin receptor 0.007 0.0737 0.0737
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0022 0.0023
Toxoplasma gondii 1-phosphatidylinositol 4-kinase 0.0024 0.017 0.0168
Trypanosoma cruzi adenosine kinase, putative 0.002 0.0116 0.0111
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0016 0.0072 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0175 0.2033 0.5509
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0267 0.0269
Echinococcus granulosus neuropeptide Y receptor 0.007 0.0737 0.077
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0059 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0108 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0117 0.0123
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.007 0.0737 0.077
Entamoeba histolytica adenosine deaminase, putative 0.011 0.1228 0.1248
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.007 0.0737 0.1978
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0032 0.0267 0.0269
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0361 0.0367
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0137 0.1564 0.16
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0172 0.0169
Trichomonas vaginalis ribokinase, putative 0.002 0.0116 0.0111
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0117 0.0292
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0016 0.0072 0.0064
Trypanosoma brucei AMP deaminase, putative 0.0309 0.3682 0.3845
Entamoeba histolytica kinase, PfkB family 0.002 0.0116 0.008
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0117 0.0123
Trypanosoma cruzi prolyl endopeptidase 0.0014 0.004 0.0031
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0509 0.3209
Leishmania major NAD synthase, putative 0.0016 0.0072 0.0064
Schistosoma mansoni adenosylhomocysteinase 0.0486 0.5866 0.6136
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0108 0.0113
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0117 0.0123
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0041 0.0043
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0036 0.0027
Echinococcus multilocularis neuropeptide Y receptor 0.007 0.0737 0.0737
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0137 0.1564 0.16
Brugia malayi Dopamine receptor 0.007 0.0737 0.077
Echinococcus granulosus neuropeptides capa receptor 0.007 0.0737 0.077
Echinococcus granulosus neuropeptide Y receptor 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0123
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0044 0.041 0.0429
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0059 0.005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0267 0.0279
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0032 0.0267 0.0269
Echinococcus granulosus hypothetical protein 0.007 0.0737 0.077
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0361 0.0377
Leishmania major S-adenosylhomocysteine hydrolase 0.0785 0.9561 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0048 0.005
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.0026 0.0103
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0048 0.005
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0032 0.0267 0.0269
Echinococcus granulosus Ankyrin 0.0015 0.005 0.0052
Schistosoma mansoni opsin-like receptor 0.007 0.0737 0.077
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0059 0.0596 0.0613
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0016 0.0072 0.0064
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0014 0.004 0.0031
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0117 0.0117
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0249 0.0261
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0117 0.0123
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0041 0.0043
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0028 0.0211 0.022
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.044 0.046
Brugia malayi intermediate filament protein 0.0027 0.0205 0.0215
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0026 0.0017
Echinococcus granulosus cGMP dependent protein kinase 0.0012 0.002 0.0021
Schistosoma mansoni protein kinase 0.0015 0.0055 0.0057
Echinococcus granulosus single minded 2 0.004 0.0361 0.0377
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.007 0.0737 0.077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0117 0.0123
Onchocerca volvulus 0.0039 0.0347 0.0918
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0737 0.077
Echinococcus multilocularis neuropeptide FF receptor 2 0.007 0.0737 0.0737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Schistosoma mansoni biogenic amine (5HT) receptor 0.007 0.0737 0.077
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0509 0.0522
Giardia lamblia NH3-dependent NAD+ synthetase 0.0016 0.0072 0.0396
Trypanosoma brucei prolyl endopeptidase 0.0014 0.004 0.0031
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0318 0.0322
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0041 0.0032
Trichomonas vaginalis set domain proteins, putative 0.024 0.2836 0.2958
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0318 0.0333
Schistosoma mansoni flap endonuclease-1 0.0024 0.0163 0.017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0117 0.0123
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0059 0.0061
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0049 0.0051
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0032 0.0267 0.0269
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0117 0.0123
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0509 0.0522
Echinococcus multilocularis concentrative Na+ nucleoside cotransporter 0.0348 0.4162 0.4162
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.002 0.0021
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0117 0.0292
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0012 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Schistosoma mansoni biogenic amine receptor 0.007 0.0737 0.077
Brugia malayi hypothetical protein 0.0165 0.1908 0.1995
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0509 0.0532
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0014 0.0041 0.0043
Loa Loa (eye worm) hypothetical protein 0.0239 0.2823 0.2953
Echinococcus granulosus tm gpcr rhodopsin 0.007 0.0737 0.077
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.007 0.0737 0.077
Echinococcus granulosus AMP deaminase 2 0.0309 0.3682 0.3851
Echinococcus multilocularis tachykinin peptides receptor 99D 0.007 0.0737 0.0737
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0028 0.0211 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0068 0.0708 0.0708
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0052 0.0513 0.0497
Leishmania major AMP deaminase, putative 0.0309 0.3682 0.3845
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0318 0.0333
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0059 0.0596 0.0624
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0028 0.0211 0.021
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0069 0.0715 0.0715
Loa Loa (eye worm) prolyl oligopeptidase 0.0175 0.2033 0.2127
Entamoeba histolytica fructokinase, putative 0.002 0.0116 0.008
Echinococcus multilocularis solute carrier family 28 0.0348 0.4162 0.4162
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0108 0.0102
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0052 0.0513 0.0527
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0737 0.0737
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0117 0.0123
Trypanosoma brucei prolyl oligopeptidase, putative 0.0014 0.004 0.0031
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0022 0.0023
Trypanosoma brucei ribokinase, putative 0.002 0.0116 0.0111
Onchocerca volvulus Huntingtin homolog 0.0124 0.1399 0.3782
Loa Loa (eye worm) hypothetical protein 0.0036 0.0318 0.0333
Trypanosoma brucei adenosine transporter 2 0.0014 0.0045 0.0036
Echinococcus granulosus g protein coupled receptor 0.007 0.0737 0.077
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0045 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Loa Loa (eye worm) hypothetical protein 0.0027 0.0199 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0108 0.0102
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0737 0.0737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0031 0.0032
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0032 0.0267 0.0279
Loa Loa (eye worm) STAT protein 0.0133 0.1512 0.1581
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0017 0.0081 0.0085
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.004 0.0042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.007 0.0737 0.077
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.007 0.0737 0.077
Schistosoma mansoni thyroid hormone receptor 0.002 0.0117 0.0123
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0052 0.0513 0.0537
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0032 0.0267 0.0269
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0137 0.1564 0.1626
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0108 0.0108
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0045 0.0036
Echinococcus multilocularis expressed conserved protein 0.0012 0.002 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0737 0.0737
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0047 0.0453 0.0463
Treponema pallidum NAD synthetase 0.0016 0.0072 0.0396
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.044 0.044
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0509 0.0522
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0083 0.0087
Trypanosoma cruzi NAD+ synthase, putative 0.0016 0.0072 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0211 0.021
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.007 0.0737 0.0737
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0057 0.0569 0.0585
Echinococcus multilocularis 0.0057 0.0569 0.0569
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0108 0.0113
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0012 0.002 0.002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0117 0.0117
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0194 0.0192
Giardia lamblia Alanyl dipeptidyl peptidase 0.0014 0.004 0.019
Trypanosoma cruzi nucleobase transporter, putative 0.0014 0.0045 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.007 0.0737 0.0737
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0026 0.0017
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0108 0.0113
Mycobacterium ulcerans adenosine deaminase 0.011 0.1228 0.1275
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0108 0.0113
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0137 0.1564 0.1635
Mycobacterium tuberculosis Conserved protein 0.0036 0.0318 0.0322
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0032 0.0267 0.0269
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0108 0.0108
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0117 0.0123
Loa Loa (eye worm) hypothetical protein 0.0082 0.0885 0.0926
Onchocerca volvulus 0.0241 0.2837 0.7699
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0048 0.005
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0318 0.0318
Schistosoma mansoni cpg binding protein 0.0031 0.0248 0.0259
Loa Loa (eye worm) hypothetical protein 0.0036 0.0318 0.0333
Echinococcus multilocularis G-protein coupled receptor, putative 0.007 0.0737 0.0737
Echinococcus multilocularis ribokinase 0.002 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0041 0.0043
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0014 0.004 0.0031
Trypanosoma brucei AMP deaminase, putative 0.0309 0.3682 0.3845
Onchocerca volvulus 0.002 0.0116 0.0288
Brugia malayi RNA, U transporter 1 0.0083 0.0893 0.0934
Echinococcus granulosus adenosylhomocysteinase 0.0785 0.9561 1
Loa Loa (eye worm) phosphatidylinositol kinase 0.0219 0.2572 0.269
Onchocerca volvulus Prolyl endopeptidase homolog 0.0014 0.004 0.0081
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0004 0.0004
Brugia malayi Adenosine kinase-like 0.0176 0.2043 0.2137
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0108 0.0113
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0069 0.0715 0.0737
Brugia malayi G protein-coupled receptor 0.007 0.0737 0.077
Echinococcus multilocularis fmrfamide receptor 0.007 0.0737 0.0737
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0267 0.0267
Entamoeba histolytica hypothetical protein 0.0032 0.0267 0.0238
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0061 0.0619 0.0647
Loa Loa (eye worm) hypothetical protein 0.002 0.0116 0.0122
Leishmania major nucleoside transporter 1, putative 0.0014 0.0045 0.0036
Loa Loa (eye worm) melatonin receptor type 1A 0.007 0.0737 0.077
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0137 0.1564 0.1626
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0785 0.9561 1
Echinococcus granulosus prolyl endopeptidase 0.0014 0.004 0.0042
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0267 0.0269
Loa Loa (eye worm) hypothetical protein 0.0031 0.0249 0.0261
Trypanosoma brucei adenosine kinase, putative 0.0176 0.2043 0.2129
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0041 0.0043
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0108 0.0113
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0014 0.004 0.0031
Schistosoma mansoni hypothetical protein 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0057 0.0569 0.0585
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0785 0.9561 1
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0069 0.0715 0.0747
Plasmodium vivax SET domain protein, putative 0.0031 0.0249 0.025
Brugia malayi Pre-SET motif family protein 0.0031 0.0249 0.0261
Schistosoma mansoni single-minded 0.0049 0.0476 0.0498
Onchocerca volvulus 0.002 0.0117 0.0292
Leishmania major hypothetical protein, unknown function 0.0032 0.0267 0.0269
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0032 0.0267 0.0269
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0059 0.0596 0.0613
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0061 0.0619 0.0619
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0137 0.1564 0.16
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0012 0.001 0.0011
Trypanosoma cruzi AMP deaminase, putative 0.0309 0.3682 0.3845
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0045 0.0036
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.2477 0.259
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0134 0.014
Brugia malayi Nucleoside transporter family protein 0.0082 0.0885 0.0926
Brugia malayi Sodium:solute symporter family protein 0.0039 0.0347 0.0363
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0016 0.0072 0.0075
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0205 0.0215
Echinococcus multilocularis sex peptide receptor 0.007 0.0737 0.0737
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0113
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.007 0.0737 0.077
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0052 0.0513 0.0497
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0309 0.3682 0.3845
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0082 0.0885 0.2382
Leishmania major nucleoside transporter 1, putative 0.0014 0.0045 0.0036
Schistosoma mansoni fkbp-rapamycin associated protein 0.0032 0.0267 0.0279
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0172 0.0169
Loa Loa (eye worm) adenosylhomocysteinase 0.0785 0.9561 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0012 0.001 0.001
Echinococcus multilocularis acylamino acid releasing enzyme 0.0014 0.004 0.004
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0032 0.0267 0.0269
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0137 0.1564 0.1626
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0052 0.0513 0.0527
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0036 0.0027
Onchocerca volvulus 0.0036 0.0318 0.0838
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0247 0.2911 0.3037
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0041 0.0041
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0117 0.0123
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0012 0.001 0.001
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0108 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0117 0.0123
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.007 0.0737 0.0737
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0043 0.0394 0.0401
Mycobacterium tuberculosis Probable peptidase 0.0014 0.004 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0737 0.077
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0069 0.0715 0.0737
Brugia malayi N-terminal motif family protein 0.0012 0.001 0.0011
Onchocerca volvulus Ribokinase homolog 0.002 0.0116 0.0288
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0017 0.0081 0.0081
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0026 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0737 0.077
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0052 0.0513 0.0527
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0513 0.0537
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0134 0.0129
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0052 0.0513 0.3238
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0108 0.0113
Echinococcus granulosus allatostatin A receptor 0.007 0.0737 0.077
Schistosoma mansoni amine GPCR 0.007 0.0737 0.077
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0032 0.0267 0.0279
Leishmania major nucleobase transporter 0.0014 0.0045 0.0036
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0041 0.0043
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0509 0.0522
Brugia malayi Dopamine receptor protein 1 0.007 0.0737 0.077
Echinococcus granulosus sex peptide receptor 0.007 0.0737 0.077
Toxoplasma gondii hypothetical protein 0.0014 0.004 0.0031
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0017 0.0081 0.0085
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.0042
Trichomonas vaginalis ribokinase, putative 0.002 0.0116 0.0111
Loa Loa (eye worm) hypothetical protein 0.0036 0.0318 0.0333
Mycobacterium ulcerans fructokinase, PfkB 0.002 0.0116 0.0111
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0052 0.0513 0.0527
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.002 0.0116 0.008
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0318 0.0322
Leishmania major phosphatidylinositol kinase related protein, putative 0.0032 0.0267 0.0269
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0318 0.0333
Schistosoma mansoni biogenic amine (dopamine) receptor 0.007 0.0737 0.077
Echinococcus granulosus sodium:glucose cotransporter 0.0039 0.0347 0.0363
Schistosoma mansoni hypothetical protein 0.0016 0.007 0.0073
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0471 0.0493
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0108 0.0113
Trichomonas vaginalis adenosine deaminase, putative 0.011 0.1228 0.1275
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0048 0.0048
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0014 0.004 0.0031
Brugia malayi Protein kinase domain containing protein 0.0015 0.0058 0.006
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0012 0.001 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0161 0.0157
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0137 0.1564 0.1626
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.002 0.0116 0.0116
Echinococcus multilocularis somatostatin receptor 0.007 0.0737 0.0737
Brugia malayi Ribokinase 0.002 0.0116 0.0122
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0039 0.0347 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0267 0.0269
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0115 0.012
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0117 0.0117
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0052 0.0513 0.0497
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0108 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0026 0.0017
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0108 0.0108
Brugia malayi Pre-SET motif family protein 0.0211 0.2477 0.259
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0312 0.3714 0.3885
Schistosoma mansoni adenosylhomocysteinase 0.0486 0.5866 0.6136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0113
Echinococcus granulosus somatostatin receptor 0.007 0.0737 0.077
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0032 0.0267 0.0279
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.0043
Brugia malayi Cytochrome P450 family protein 0.0012 0.0022 0.0023
Trypanosoma brucei protein kinase, putative 0.0052 0.0509 0.0522
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.044 0.046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0737 0.077
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0045 0.0036
Echinococcus multilocularis G protein coupled receptor 139 0.007 0.0737 0.0737
Giardia lamblia Rrm3p helicase 0.0028 0.0211 0.1289
Schistosoma mansoni hypothetical protein 0.007 0.0737 0.077
Brugia malayi prolyl oligopeptidase family protein 0.0175 0.2033 0.2127
Trypanosoma brucei adenosine transporter 2 0.0014 0.0045 0.0036
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0318 0.0322
Echinococcus granulosus neuropeptide FF receptor 2 0.007 0.0737 0.077
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0267 0.0279
Trypanosoma cruzi nucleoside transporter 1, putative 0.0014 0.0045 0.0036
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0026 0.0017
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0069 0.0715 0.0747
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0737 0.077
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0059 0.0059
Schistosoma mansoni adenoreceptor 0.007 0.0737 0.077
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0737 0.0737
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0012 0.001 0.0011
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0082 0.0885 0.0885
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0012 0.001 0.0011
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0318 0.0333
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0012 0.001 0.0011
Schistosoma mansoni histamine h1 receptor 0.007 0.0737 0.077
Entamoeba histolytica hypothetical protein 0.0019 0.0108 0.0071
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0108 0.0113
Brugia malayi MH2 domain containing protein 0.0116 0.1305 0.1365
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0059 0.005
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0057 0.0569 0.0585
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0227 0.0238
Plasmodium vivax adenosine deaminase, putative 0.011 0.1228 0.1275
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0032 0.0267 0.0269
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0057 0.0569 0.0595
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0137 0.1564 0.1626
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0026 0.0017
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0318 0.0322
Schistosoma mansoni AMP deaminase 0.0309 0.3682 0.3851
Brugia malayi hypothetical protein 0.0036 0.0313 0.0328
Toxoplasma gondii nucleoside transporter protein 0.0014 0.0045 0.0036
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0052 0.0513 0.0537
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.002 0.0116 0.0122
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0737 0.077
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0052 0.0513 0.0527
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0052 0.0513 0.0527
Echinococcus multilocularis serine protein kinase ATM 0.0032 0.0267 0.0267
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0032 0.0267 0.0269
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.044 0.046
Brugia malayi PXA domain containing protein 0.0019 0.0108 0.0113
Brugia malayi Serotonin receptor 0.007 0.0737 0.077
Echinococcus multilocularis lamin 0.0027 0.0205 0.0205
Schistosoma mansoni adenosylhomocysteinase 0.0785 0.9561 1
Echinococcus granulosus equilibrative nucleoside transporter 0.0082 0.0885 0.0926
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0048 0.0048
Onchocerca volvulus 0.0013 0.0026 0.0043
Toxoplasma gondii phosphatidylinositol 4-kinase 0.0024 0.017 0.0168
Schistosoma mansoni adenosylhomocysteinase 0.0486 0.5866 0.6136
Schistosoma mansoni biogenic amine (dopamine) receptor 0.007 0.0737 0.077
Echinococcus granulosus dro:myosuppressin receptor 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Schistosoma mansoni lamin 0.0027 0.0205 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0509 0.0532
Echinococcus granulosus serotonin receptor 0.007 0.0737 0.077
Echinococcus granulosus neuropeptide receptor 0.007 0.0737 0.077
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0737 0.0737
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0108 0.0113
Brugia malayi hypothetical protein 0.0019 0.0108 0.0113
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.041 0.041
Echinococcus granulosus high affinity choline transporter 1 0.0352 0.4211 0.4405
Brugia malayi hypothetical protein 0.0016 0.007 0.0073
Entamoeba histolytica hypothetical protein 0.0032 0.0267 0.0238
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0036 0.0027
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0047 0.0454 0.0464
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0509 0.0532
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0041 0.0043
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0032 0.0267 0.0269
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.002 0.0021
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0117 0.0123
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0267 0.0269
Toxoplasma gondii nucleoside transporter protein 0.0014 0.0045 0.0036
Mycobacterium tuberculosis Conserved protein 0.0036 0.0318 0.0322
Entamoeba histolytica hypothetical protein 0.0019 0.0108 0.0071
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0118 0.0118
Brugia malayi Serotonin/octopamine receptor family protein 7 0.007 0.0737 0.077
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.009 0.0978 0.1013
Entamoeba histolytica protein kinase rad3, putative 0.0032 0.0267 0.0238
Onchocerca volvulus 0.0036 0.0318 0.0838
Loa Loa (eye worm) TYRA-2 protein 0.007 0.0737 0.077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0052 0.0513 0.0527
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0117 0.0123
Echinococcus multilocularis cpg binding protein 0.0031 0.0248 0.0248
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0043 0.0394 0.0401
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0318 0.0322
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0175 0.2033 0.2127
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0113
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0134 0.0129
Onchocerca volvulus 0.007 0.0737 0.1978
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0267 0.0279
Schistosoma mansoni growth hormone secretagogue receptor 0.007 0.0737 0.077
Schistosoma mansoni ribokinase 0.002 0.0116 0.0122
Plasmodium falciparum AMP deaminase, putative 0.0309 0.3682 0.3845
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0117 0.0123
Loa Loa (eye worm) neuropeptide F receptor 0.007 0.0737 0.077
Schistosoma mansoni neuropeptide F-like receptor 0.007 0.0737 0.077
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.044 0.046
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0032 0.0267 0.0269
Trypanosoma cruzi adenosine kinase, putative 0.0176 0.2043 0.2129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Trichomonas vaginalis adenosine deaminase, putative 0.011 0.1228 0.1275
Echinococcus granulosus Na+ dependent nucleoside transporter 0.0348 0.4162 0.4353
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.0042
Loa Loa (eye worm) AGC/PKG protein kinase 0.0012 0.002 0.0021
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0048 0.0102
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0061 0.0619 0.0637
Loa Loa (eye worm) hypothetical protein 0.002 0.0116 0.0122
Leishmania major tagatose-6-phosphate kinase-like protein 0.002 0.0116 0.0111
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0509 0.0522
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0082 0.0885 0.0926
Brugia malayi hypoxia-induced factor 1 0.0152 0.175 0.183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus multilocularis neuropeptide receptor 0.007 0.0737 0.0737
Echinococcus multilocularis musashi 0.0027 0.0205 0.0205
Echinococcus multilocularis Zinc finger, PHD finger 0.0052 0.0513 0.0513
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0123
Echinococcus multilocularis neuropeptides capa receptor 0.007 0.0737 0.0737
Plasmodium vivax GMP synthetase, putative 0.0061 0.0619 0.0637
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0117 0.0123
Brugia malayi nuclear receptor NHR-88 0.002 0.0117 0.0123
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0318 0.0322
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Leishmania major protein kinase, putative 0.0014 0.0036 0.0027
Brugia malayi putative neuropeptide receptor NPR1 0.007 0.0737 0.077
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0045 0.0036
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0052 0.0513 0.0497
Trypanosoma cruzi oligopeptidase b 0.0014 0.004 0.0031
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0026 0.0026
Echinococcus multilocularis solute carrier family 5 0.0039 0.0347 0.0347
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0082 0.0885 0.0916
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0108 0.0113
Trypanosoma cruzi nucleoside transporter-like, putative 0.0014 0.0045 0.0036
Echinococcus granulosus lamin 0.0027 0.0205 0.0215
Loa Loa (eye worm) hypothetical protein 0.0013 0.0026 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0249 0.0261
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0117 0.0117
Echinococcus granulosus tachykinin peptides receptor 99D 0.007 0.0737 0.077
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0137 0.1564 0.1635
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0108 0.0102
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0229 0.0229
Onchocerca volvulus 0.007 0.0737 0.1978
Schistosoma mansoni inositol transporter 0.0039 0.0347 0.0363
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1305 0.1365
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0039 0.0347 0.0347
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0059 0.0059
Loa Loa (eye worm) neuropeptide F receptor 0.007 0.0737 0.077
Brugia malayi hypothetical protein 0.007 0.0737 0.077
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0509 0.0522
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0785 0.9561 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.007 0.0737 0.077
Brugia malayi GMP synthase 0.0061 0.0619 0.0647
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0509 0.0509
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0117 0.0123
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0014 0.0041 0.0041
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0108 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Echinococcus granulosus tm gpcr rhodopsin 0.007 0.0737 0.077
Leishmania major protein kinase, putative 0.0012 0.002 0.001
Onchocerca volvulus 0.007 0.0737 0.1978
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0117 0.0117
Leishmania major protein kinase, putative 0.0025 0.0178 0.0175
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0032 0.0267 0.0269
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0137 0.1564 0.1626
Echinococcus granulosus sodium:myo inositol cotransporter 0.0039 0.0347 0.0363
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0022 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0117 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0318 0.0322
Echinococcus multilocularis adenosylhomocysteinase 0.0785 0.9561 0.9561
Entamoeba histolytica hypothetical protein 0.0052 0.0513 0.0497
Loa Loa (eye worm) hypothetical protein 0.0032 0.0267 0.0279
Echinococcus multilocularis adenosine kinase 0.0176 0.2043 0.2043
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0108 0.0113
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0172 0.0169
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.007 0.0737 0.0737
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.009 0.0979 0.0979
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0108 0.0108
Schistosoma mansoni neuropeptide receptor 0.007 0.0737 0.077
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.002 0.0116 0.0111
Loa Loa (eye worm) hypothetical protein 0.0176 0.2043 0.2137
Trypanosoma cruzi NAD+ synthase, putative 0.0016 0.0072 0.0064
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0032 0.0267 0.0269
Leishmania major hypothetical protein, conserved 0.011 0.1228 0.1275
Brugia malayi Flap endonuclease-1 0.0026 0.0194 0.0203
Schistosoma mansoni hypothetical protein 0.007 0.0737 0.077
Echinococcus granulosus microtubule associated protein 2 0.0699 0.849 0.8881
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0267 0.0279
Schistosoma mansoni amine GPCR 0.007 0.0737 0.077
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0117 0.0292
Plasmodium vivax hypothetical protein 0.0032 0.0267 0.0269
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0117 0.0117
Trypanosoma brucei ribokinase, putative 0.002 0.0116 0.0111
Echinococcus granulosus peptide allatostatin:somatostatin 0.007 0.0737 0.077
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0172 0.0169
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0052 0.0513 0.0537
Brugia malayi gonadotropin-releasing hormone receptor 2 0.007 0.0737 0.077
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0083 0.0083
Brugia malayi beta-lactamase 0.0036 0.0318 0.0333
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.001 0.0011
Loa Loa (eye worm) beta-lactamase 0.0036 0.0318 0.0333
Onchocerca volvulus 0.007 0.0737 0.1978
Entamoeba histolytica NAD synthetase, putative 0.0016 0.0072 0.0034
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0016 0.0072 0.0064
Schistosoma mansoni amine GPCR 0.007 0.0737 0.077
Echinococcus granulosus neuropeptide s receptor 0.007 0.0737 0.077
Onchocerca volvulus 0.0027 0.0205 0.0531
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0057 0.0569 0.0595
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0267 0.0279
Leishmania major phosphatidylinositol kinase, putative 0.0032 0.0267 0.0269
Echinococcus multilocularis lamin dm0 0.0027 0.0205 0.0205
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0052 0.0513 0.0527
Onchocerca volvulus Huntingtin homolog 0.0124 0.1399 0.3782
Echinococcus granulosus 7TM GPCR rhodopsin 0.007 0.0737 0.077
Entamoeba histolytica adenosine deaminase, putative 0.011 0.1228 0.1248
Brugia malayi Adenosine/AMP deaminase family protein 0.011 0.1228 0.1285
Mycobacterium ulcerans hypothetical protein 0.0036 0.0318 0.0322
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0059 0.005
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0047 0.0454 0.0464
Brugia malayi Death domain containing protein 0.0015 0.0048 0.005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0059 0.0059
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0137 0.1564 0.1635
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Brugia malayi adenosine monophosphate deaminase 0.0309 0.3682 0.3851
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.007 0.0737 0.077
Schistosoma mansoni hypothetical protein 0.0172 0.1986 0.2077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0043 0.0394 0.0401
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0453 0.0474
Brugia malayi Adenosylhomocysteinase 0.0785 0.9561 1
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0082 0.0885 0.2382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0137 0.1564 0.1626
Echinococcus granulosus g protein coupled receptor 0.007 0.0737 0.077
Leishmania major hypothetical protein, conserved 0.0032 0.0267 0.0269
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0014 0.004 0.0042
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0137 0.1564 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0047 0.0453 0.0474
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0043 0.0394 0.0412
Schistosoma mansoni hypothetical protein 0.007 0.0737 0.077
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0785 0.9561 1
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0453 0.0474
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0118 0.0123
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0118 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0267 0.0269
Trypanosoma brucei cytochrome P450, putative 0.0012 0.0022 0.0012
Brugia malayi neuropeptide F receptor 0.007 0.0737 0.077
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.007 0.0737 0.077
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.007 0.0737 0.0737
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0309 0.3682 0.3845
Mycobacterium leprae Probable GMP synthase [glutamine-hydrolyzing] GuaA (Glutamine amidotransferase) (GMP synthetase) 0.0022 0.0145 0.0141
Brugia malayi isocitrate dehydrogenase 0.0015 0.0059 0.0061
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0229 0.0229
Mycobacterium leprae Probable lipase LipE 0.0036 0.0318 0.0322
Mycobacterium ulcerans lipase LipD 0.0036 0.0318 0.0322
Brugia malayi neuropeptide F receptor 0.007 0.0737 0.077
Loa Loa (eye worm) hypothetical protein 0.007 0.0737 0.077

Activities

Activity type Activity value Assay description Source Reference
PFA (functional) = -27 Percent change in volume of foot edema of test compound to that of positive control was determined at a dose of 31.6 mg/kg in rat; -27/-65 ChEMBL. 2342077

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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