Detailed information for compound 883837

Basic information

Technical information
  • TDR Targets ID: 883837
  • Name: 2-(3,4-dimethoxyphenyl)-3-[(4-hydroxy-3-metho xyphenyl)methyl]-1,3-thiazolidin-4-one
  • MW: 375.439 | Formula: C19H21NO5S
  • H donors: 1 H acceptors: 2 LogP: 2.86 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(ccc1OC)C1SCC(=O)N1Cc1ccc(c(c1)OC)O
  • InChi: 1S/C19H21NO5S/c1-23-15-7-5-13(9-17(15)25-3)19-20(18(22)11-26-19)10-12-4-6-14(21)16(8-12)24-2/h4-9,19,21H,10-11H2,1-3H3
  • InChiKey: IYJRYOKLVGQQOP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(3,4-dimethoxyphenyl)-3-[(4-hydroxy-3-methoxy-phenyl)methyl]thiazolidin-4-one
  • 2-(3,4-dimethoxyphenyl)-3-[(4-hydroxy-3-methoxyphenyl)methyl]-4-thiazolidinone
  • 2-(3,4-dimethoxyphenyl)-3-(4-hydroxy-3-methoxy-benzyl)thiazolidin-4-one
  • 2-(3,4-dimethoxyphenyl)-3-[(4-hydroxy-3-methoxy-phenyl)methyl]-1,3-thiazolidin-4-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0015 0.011
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0201 0.0114 0.0202
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0007 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Toxoplasma gondii Nucleoside-diphosphatase 0.0094 0.0048 0.039
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0077
Echinococcus granulosus neuropeptide receptor A26 0.0707 0.0425 0.0755
Entamoeba histolytica cysteine protease, putative 0.0018 0.0002 0.0005
Echinococcus granulosus 7TM GPCR rhodopsin 0.0201 0.0114 0.0202
Echinococcus granulosus carbonic anhydrase 0.0807 0.0487 0.0865
Onchocerca volvulus 0.0201 0.0114 0.0627
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0021 0.0038
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0021 0.0162
Entamoeba histolytica hypothetical protein 0.005 0.0021 0.0084
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.008
Schistosoma mansoni biogenic amine receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0002 0.0004
Schistosoma mansoni SET domain protein 0.002 0.0003 0.0005
Brugia malayi PAS domain containing protein 0.0051 0.0022 0.0167
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0023 0.004
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0201 0.0114 0.0202
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0187 0.0106 0.0104
Brugia malayi steroid hormone receptor 0.0033 0.0011 0.008
Loa Loa (eye worm) hypothetical protein 0.0078 0.0038 0.0289
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0004 0.0002
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0027 0.0048
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0013 0.0013
Echinococcus granulosus pyruvate kinase 0.0019 0.0002 0.0004
Onchocerca volvulus 0.0201 0.0114 0.0627
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0011 0.0019
Trypanosoma brucei phosphoglycerate kinase, putative 0.0069 0.0033 0.0241
Brugia malayi hypothetical protein 0.0017 0.0001 0.0009
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0201 0.0114 0.0857
Schistosoma mansoni carbonic anhydrase-related 0.0807 0.0487 0.0865
Echinococcus multilocularis hypothetical protein 0.003 0.0009 0.0015
Echinococcus granulosus g-protein coupled receptor 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0201 0.0114 0.0627
Chlamydia trachomatis sulfate transporter 0.0473 0.0281 1
Schistosoma mansoni lipoxygenase 0.0128 0.0069 0.0122
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0215 0.0122 0.0917
Echinococcus granulosus neuropeptides capa receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) CHromoDomain protein family member 0.0018 0.0002 0.0012
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0061 0.0028 0.0212
Chlamydia trachomatis pyruvate kinase 0.0037 0.0013 0.038
Giardia lamblia Hypothetical protein 0.0803 0.0484 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0324 0.019 0.0767
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0013 0.0098
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0215 0.0122 0.0923
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0004 0.0007
Onchocerca volvulus 0.0053 0.0023 0.0127
Trypanosoma cruzi nucleoside phosphatase, putative 0.0094 0.0048 0.0359
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0007 0.0004
Schistosoma mansoni phosphoglycerate kinase 0.0187 0.0106 0.0188
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.003 0.0053
Schistosoma mansoni guanosine-diphosphatase 0.0094 0.0048 0.0086
Echinococcus granulosus pyruvate kinase 0.0019 0.0002 0.0004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0004 0.0011
Plasmodium falciparum nucleoside-diphosphatase, putative 0.0094 0.0048 0.096
Onchocerca volvulus 0.0201 0.0114 0.0627
Echinococcus granulosus peptide allatostatin:somatostatin 0.0201 0.0114 0.0202
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0015 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0004 0.0002
Echinococcus granulosus somatostatin receptor 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0179 0.01 0.0553
Echinococcus multilocularis serotonin receptor 0.168 0.1023 0.1818
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0035 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0121 0.0065 0.0073
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0013 0.0094
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0001 0.0002
Echinococcus granulosus RUN 0.0061 0.0028 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Echinococcus granulosus histone acetyltransferase KAT2B 0.0156 0.0087 0.0154
Schistosoma mansoni P2X receptor subunit 0.4729 0.2898 0.5146
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni phosphoglycerate kinase 0.0187 0.0106 0.0188
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0333 0.0195 0.1463
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0004 0.0024
Onchocerca volvulus 0.2967 0.1815 1
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.001 0.0067
Echinococcus granulosus p2X purinoceptor 4 0.9174 0.5631 1
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.3427 0.2098 0.2415
Toxoplasma gondii hypothetical protein 0.0054 0.0023 0.0181
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0023 0.004
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0007 0.0024
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0163 0.0091 0.0161
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.0011 0.0059
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.001 0.0007
Echinococcus granulosus 7tm_1 domain containing protein 0.0201 0.0114 0.0202
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0045 0.0018 0.0032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.019 0.0188
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0015 0.0016
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.0011 0.008
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0201 0.0114 0.0202
Onchocerca volvulus Putative sulfate transporter 0.2967 0.1815 1
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.005 0.0021 0.0679
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.003 0.0053
Brugia malayi hypothetical protein 0.0173 0.0097 0.0728
Loa Loa (eye worm) hypothetical protein 0.026 0.0151 0.1134
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.001 0.0073
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.003 0.0028
Toxoplasma gondii exonuclease III APE 0.004 0.0015 0.0113
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0123 0.0066 0.0266
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0023 0.0174
Echinococcus granulosus G protein coupled receptor 139 0.0201 0.0114 0.0202
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.001 0.0018
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0015 0.006
Schistosoma mansoni chromobox protein 0.0077 0.0038 0.0067
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0026 0.0186
Brugia malayi Cytochrome P450 family protein 0.0081 0.004 0.0304
Mycobacterium leprae Probable transmembrane transport protein 0.3427 0.2098 0.85
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0018 0.0002 0.001
Echinococcus granulosus g protein coupled receptor 0.0201 0.0114 0.0202
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0004 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0007 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0032 0.001 0.0301
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis somatostatin receptor 0.0201 0.0114 0.0202
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.001 0.007
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.0011 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0201 0.0114 0.0202
Schistosoma mansoni biogenic amine (5HT) receptor 0.3519 0.2154 0.3825
Trypanosoma brucei cytochrome P450, putative 0.0031 0.001 0.0067
Onchocerca volvulus 0.0033 0.0011 0.0059
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0004 0.0002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0002 0.0014
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.0011 0.0059
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0015 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Loa Loa (eye worm) hypothetical protein 0.168 0.1023 0.771
Schistosoma mansoni opsin-like receptor 0.0201 0.0114 0.0202
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0004 0.0002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0017 0.0093
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0201 0.0114 0.0202
Trichomonas vaginalis chromobox protein, putative 0.0077 0.0038 0.0036
Schistosoma mansoni P2X receptor subunit 0.9174 0.5631 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0002 0.0004
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0215 0.0122 0.0217
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0004 0.0002
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0201 0.0114 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0201 0.0114 0.0202
Schistosoma mansoni amine GPCR 0.0201 0.0114 0.0202
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0011 0.008
Plasmodium vivax nucleoside-diphosphatase mig-23, putative 0.0094 0.0048 0.1668
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0065
Leishmania major cathepsin L-like protease 0.007 0.0034 0.0133
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0158 0.0088 0.0085
Brugia malayi Pre-SET motif family protein 0.0035 0.0012 0.0092
Mycobacterium tuberculosis Conserved hypothetical protein 0.0175 0.0098 0.0111
Brugia malayi Bromodomain containing protein 0.009 0.0046 0.0345
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0015 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.0011 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Echinococcus granulosus pyruvate kinase 0.0037 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.008
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0004 0.0002
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0465 0.0277 0.0491
Schistosoma mansoni guanine nucleotide-binding protein beta 1 4 (G protein beta1 4) 0.0045 0.0018 0.0032
Schistosoma mansoni amine GPCR 0.0201 0.0114 0.0202
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0069 0.0033 0.0241
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0094 0.0048 0.0365
Trypanosoma brucei DNA polymerase eta, putative 0.0049 0.0021 0.015
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus granulosus lipoxygenase domain containing protein 0.0061 0.0028 0.005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0087 0.0651
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0039 0.0014 0.0025
Toxoplasma gondii 5'-nucleotidase, C-terminal domain-containing protein 0.1964 0.1198 1
Brugia malayi mbt repeat family protein 0.0053 0.0023 0.0172
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Loa Loa (eye worm) hypothetical protein 0.0807 0.0487 0.3668
Echinococcus granulosus hypothetical protein 0.0201 0.0114 0.0202
Toxoplasma gondii kringle domain-containing protein 0.0023 0.0005 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.0011 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.0011 0.008
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0465 0.0277 0.0491
Schistosoma mansoni guanosine-diphosphatase 0.0094 0.0048 0.0086
Echinococcus granulosus GPCR family 2 0.0017 0.0001 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Giardia lamblia Fructose-bisphosphate aldolase 0.0324 0.019 0.3896
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.0011 0.008
Brugia malayi neuropeptide F receptor 0.0201 0.0114 0.0857
Leishmania major hypothetical protein, conserved 0.0023 0.0005 0.0016
Echinococcus granulosus plexin a4 0.0084 0.0042 0.0075
Giardia lamblia PHD finger protein 15 0.0032 0.001 0.0169
Schistosoma mansoni ATP-diphosphohydrolase 1 0.0465 0.0277 0.0491
Plasmodium vivax phosphoglycerate kinase, putative 0.0187 0.0106 0.3721
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.001 0.0067
Onchocerca volvulus 0.0201 0.0114 0.0627
Brugia malayi hypothetical protein 0.003 0.0009 0.0065
Loa Loa (eye worm) hypothetical protein 0.0807 0.0487 0.3668
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0005 0.003
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.005 0.0021 0.0023
Echinococcus multilocularis Polycystic kidney disease protein 0.0061 0.0028 0.005
Schistosoma mansoni adenosine diphosphatase 0.0094 0.0048 0.0086
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0004
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0024 0.0172
Schistosoma mansoni coup transcription factor 0.0033 0.0011 0.0019
Schistosoma mansoni carbonic anhydrase 0.4028 0.2467 0.4381
Echinococcus granulosus g protein coupled receptor 0.0201 0.0114 0.0202
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0004 0.0002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0024 0.0172
Trichomonas vaginalis chromobox protein, putative 0.0077 0.0038 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0011 0.0019
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0807 0.0487 0.3668
Loa Loa (eye worm) melatonin receptor type 1A 0.0201 0.0114 0.0857
Brugia malayi Doublecortin family protein 0.0061 0.0028 0.0212
Schistosoma mansoni loxhd1 0.0061 0.0028 0.005
Echinococcus multilocularis dna polymerase eta 0.0049 0.0021 0.0037
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0019 0.0139
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0009
Plasmodium falciparum phosphoglycerate kinase 0.0187 0.0106 0.2142
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.008
Brugia malayi jmjC domain containing protein 0.0044 0.0018 0.0134
Trichomonas vaginalis protein phosphatase 2C delta isoform, putative 0.0123 0.0066 0.0064
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0021 0.0019
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0023 0.004
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.005 0.0021 0.0019
Schistosoma mansoni neuropeptide receptor 0.0201 0.0114 0.0202
Schistosoma mansoni hypothetical protein 0.0023 0.0004 0.0008
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0001 0.0002
Schistosoma mansoni SET domain protein 0.0039 0.0014 0.0025
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0014 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0011 0.008
Schistosoma mansoni hypothetical protein 0.003 0.0009 0.0015
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0004 0.0002
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0014 0.0011
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0013 0.0098
Onchocerca volvulus 0.0201 0.0114 0.0627
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.0011 0.0019
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0015 0.006
Brugia malayi larval opioid receptor 0.0201 0.0114 0.0857
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0065
Schistosoma mansoni biogenic amine receptor 0.0201 0.0114 0.0202
Echinococcus granulosus tm gpcr rhodopsin 0.0201 0.0114 0.0202
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0007 0.001
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0003
Trichomonas vaginalis adenosine diphosphatase, putative 0.0094 0.0048 0.0047
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.0011 0.008
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0201 0.0114 0.0857
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0201 0.0114 0.0202
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0002
Echinococcus granulosus FTZ F1 alpha 0.0033 0.0011 0.0019
Onchocerca volvulus 0.0201 0.0114 0.0627
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0034 0.0248
Echinococcus granulosus lipoxygenase domain containing protein 0.0061 0.0028 0.005
Echinococcus granulosus cathepsin l1 0.0018 0.0002 0.0003
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.0011 0.008
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.0011 0.0019
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0023 0.004
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0187 0.0106 0.0869
Schistosoma mansoni DNA polymerase eta 0.0049 0.0021 0.0037
Brugia malayi nuclear receptor NHR-88 0.0033 0.0011 0.008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0008 0.0014
Schistosoma mansoni neuropeptide F-like receptor 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0038 0.0014 0.0076
Plasmodium falciparum inorganic anion exchanger, inorganic anion antiporter 0.0473 0.0281 0.5757
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0004 0.0027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0004 0.0002
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0004 0.0002
Onchocerca volvulus 0.0201 0.0114 0.0627
Leishmania major DNA polymerase eta, putative 0.0049 0.0021 0.0081
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.008
Leishmania major phosphoglycerate kinase B, cytosolic 0.0187 0.0106 0.0425
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.0011 0.008
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0004 0.0024
Leishmania major DNA polymerase eta, putative 0.0035 0.0012 0.0044
Brugia malayi Bromodomain containing protein 0.0039 0.0014 0.0107
Schistosoma mansoni carbonic anhydrase-related 0.0807 0.0487 0.0865
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0201 0.0114 0.0202
Echinococcus granulosus peregrin 0.0049 0.0021 0.0037
Trichomonas vaginalis protein phosphatase 2C, putative 0.0123 0.0066 0.0064
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0024 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0021 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0201 0.0114 0.0202
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.0011 0.0019
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0333 0.0195 0.1463
Brugia malayi Putative carbonic anhydrase 5 precursor 0.2175 0.1327 1
Brugia malayi Guanine nucleotide-binding protein beta subunit 1, putative 0.0045 0.0018 0.0136
Brugia malayi Heterochromatin protein 1 0.0077 0.0038 0.0284
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.2175 0.1327 0.2357
Brugia malayi Serotonin receptor 0.0201 0.0114 0.0857
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0017 0.0067
Echinococcus multilocularis semaphorin 5B 0.003 0.0009 0.0015
Echinococcus multilocularis neuropeptides capa receptor 0.0201 0.0114 0.0202
Schistosoma mansoni hypothetical protein 0.0038 0.0014 0.0024
Toxoplasma gondii NTPase II 0.0094 0.0048 0.039
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0007 0.0023
Schistosoma mansoni P2X receptor subunit 0.9174 0.5631 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0036
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Trypanosoma brucei carbonic anhydrase-like protein 0.2175 0.1327 1
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0002 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0007 0.0005
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0024 0.0178
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0015 0.0276
Brugia malayi putative neuropeptide receptor 0.0201 0.0114 0.0857
Loa Loa (eye worm) hypothetical protein 0.0049 0.002 0.0154
Schistosoma mansoni P2X receptor subunit 0.4729 0.2898 0.5146
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0007 0.0005
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0201 0.0114 0.0202
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0004 0.0018
Echinococcus multilocularis tissue type plasminogen activator 0.0023 0.0005 0.0009
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0473 0.0281 0.2113
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0082 0.0041 0.0303
Echinococcus multilocularis pyruvate kinase 0.0019 0.0002 0.0004
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0473 0.0281 0.0279
Loa Loa (eye worm) hypothetical protein 0.0053 0.0023 0.0172
Plasmodium falciparum LCCL domain-containing protein 0.0061 0.0028 0.0542
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0187 0.0106 0.0869
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0002 0.0007
Brugia malayi Plexin repeat family protein 0.0071 0.0034 0.0257
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0018 0.0032
Loa Loa (eye worm) fibroinase 0.0018 0.0002 0.0014
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0007 0.0049
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.0011 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.002
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0004 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0013 0.0013
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0648 0.0389 0.0387
Loa Loa (eye worm) hypothetical protein 0.0041 0.0016 0.0119
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.003 0.0053
Onchocerca volvulus 0.0018 0.0002 0.001
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0012 0.0083
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0007 0.0004
Trypanosoma brucei nucleoside diphosphatase, putative 0.0094 0.0048 0.0359
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0201 0.0114 0.0202
Echinococcus multilocularis L aminoadipate semialdehyde 0.0179 0.01 0.0178
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0021 0.0038
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0004 0.0002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0001 0.0002
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0023 0.004
Echinococcus granulosus cpg binding protein 0.0067 0.0032 0.0057
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0187 0.0106 0.0791
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0021 0.0162
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0001 0.0002
Echinococcus multilocularis thyroid hormone receptor alpha 0.0033 0.0011 0.0019
Brugia malayi AKH receptor 0.0201 0.0114 0.0857
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0023 0.004
Onchocerca volvulus Neuropeptide F receptor homolog 0.0201 0.0114 0.0627
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0002
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0473 0.0281 0.0279
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0015 0.0027
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0024 0.0172
Leishmania major cytochrome p450-like protein 0.0022 0.0004 0.0013
Echinococcus granulosus serotonin receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis phosphoglycerate kinase 1 0.0187 0.0106 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0017 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.019 0.0188
Echinococcus granulosus dro:myosuppressin receptor 0.0201 0.0114 0.0202
Trypanosoma brucei unspecified product 0.0021 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0201 0.0114 0.0202
Brugia malayi follicle stimulating hormone receptor 0.0201 0.0114 0.0857
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0105 0.0055 0.0098
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0019 0.0017
Echinococcus granulosus chromobox protein 1 0.0077 0.0038 0.0067
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0023 0.0005 0.0107
Brugia malayi Dopamine receptor protein 1 0.0201 0.0114 0.0857
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.0011 0.0059
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0001 0.0002
Schistosoma mansoni plexin 0.0041 0.0016 0.0028
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0023 0.0005 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.0011 0.008
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0094 0.0048 0.039
Treponema pallidum 5'-nucleotidase (ushA) 0.1964 0.1198 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0015 0.011
Trypanosoma brucei protein kinase, putative 0.0054 0.0024 0.0172
Echinococcus multilocularis pyruvate kinase 0.0029 0.0008 0.0015
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.0011 0.0019
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0157 0.0087 0.0651
Onchocerca volvulus 0.0201 0.0114 0.0627
Brugia malayi hypothetical protein 0.0061 0.0028 0.0212
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0201 0.0114 0.0202
Echinococcus multilocularis sex peptide receptor 0.0201 0.0114 0.0202
Schistosoma mansoni rab6-interacting 0.0061 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0013 0.0098
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0004 0.0007
Echinococcus multilocularis g protein coupled receptor 0.0201 0.0114 0.0202
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0024 0.0182
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.2175 0.1327 0.2357
Brugia malayi F/Y-rich N-terminus family protein 0.0034 0.0011 0.0085
Loa Loa (eye worm) cytochrome P450 family protein 0.0081 0.004 0.0304
Brugia malayi PHD-finger family protein 0.0035 0.0012 0.009
Chlamydia trachomatis phosphoglycerate kinase 0.0187 0.0106 0.3706
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.0011 0.008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0012 0.0022
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0013 0.0072
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0004 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.168 0.1023 0.1818
Leishmania major ATP diphosphohydrolase 0.0094 0.0048 0.0193
Schistosoma mansoni guanine nucleotide-binding protein beta 1 4 (G protein beta1 4) 0.0045 0.0018 0.0032
Echinococcus granulosus lysine specific demethylase 5A 0.0044 0.0018 0.0032
Brugia malayi GnHR receptor homolog 0.0201 0.0114 0.0857
Plasmodium falciparum phd finger protein, putative 0.0032 0.001 0.0173
Mycobacterium ulcerans hypothetical protein 0.0026 0.0007 0.0004
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0061 0.0028 0.0155
Echinococcus multilocularis rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.003 0.0028
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0013 0.0098
Echinococcus granulosus orexin receptor type 2 0.0201 0.0114 0.0202
Toxoplasma gondii hypothetical protein 0.0807 0.0487 0.4056
Loa Loa (eye worm) CYP4Cod1 0.0031 0.001 0.0073
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0021 0.0038
Schistosoma mansoni carbonic anhydrase 0.0807 0.0487 0.0865
Onchocerca volvulus 0.0062 0.0028 0.0157
Echinococcus multilocularis cpg binding protein 0.0067 0.0032 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0201 0.0114 0.0202
Brugia malayi Cytochrome P450 family protein 0.0031 0.001 0.0073
Echinococcus multilocularis g protein coupled receptor 0.0201 0.0114 0.0202
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0012 0.0083
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.019 0.0188
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0019 0.0104
Brugia malayi plexin A 0.0084 0.0042 0.0317
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0201 0.0114 0.0202
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0004 0.0002
Schistosoma mansoni polycystin 1-related 0.0061 0.0028 0.005
Onchocerca volvulus 0.0919 0.0555 0.3061
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0038 0.0014 0.0102
Onchocerca volvulus 0.0018 0.0002 0.001
Onchocerca volvulus 0.0034 0.0011 0.0062
Loa Loa (eye worm) doublecortin family protein 0.0061 0.0028 0.0212
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis carbonic anhydrase 0.0807 0.0487 0.0865
Echinococcus multilocularis neuropeptide receptor 0.0201 0.0114 0.0202
Schistosoma mansoni zinc finger protein 0.0029 0.0008 0.0015
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0043 0.0017 0.0127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0007 0.0005
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.001
Brugia malayi Inositol-1 0.0041 0.0015 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0024 0.0022
Schistosoma mansoni neuropeptide receptor 0.0201 0.0114 0.0202
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.2175 0.1327 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0004 0.0002
Leishmania major pyruvate kinase 0.0037 0.0013 0.005
Echinococcus granulosus chromobox protein 1 0.0077 0.0038 0.0067
Schistosoma mansoni G-protein beta subunit 0.0045 0.0018 0.0032
Loa Loa (eye worm) heterochromatin protein 1 0.0077 0.0038 0.0284
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0011 0.0019
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0034 0.0248
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0232 0.0133 0.1002
Brugia malayi hypothetical protein 0.0017 0.0001 0.0009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0201 0.0114 0.0857
Loa Loa (eye worm) hypothetical protein 0.0187 0.0106 0.0796
Trichomonas vaginalis conserved hypothetical protein 1.6282 1 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0004 0.0002
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0465 0.0277 0.0491
Echinococcus granulosus carbonic anhydrase 0.0807 0.0487 0.0865
Plasmodium falciparum apyrase, putative 0.0465 0.0277 0.5666
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0003 0.0001
Echinococcus granulosus neuropeptide s receptor 0.0707 0.0425 0.0755
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0004 0.0002
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0215 0.0122 0.0494
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0002 0.0003
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0006 0.0047
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Plasmodium falciparum carbonic anhydrase 0.0807 0.0487 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.0011 0.008
Toxoplasma gondii 5'-nucleotidase, C-terminal domain-containing protein 0.0808 0.0487 0.4061
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0011 0.008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.0011 0.0019
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0065
Echinococcus granulosus biogenic amine 5HT receptor 0.3519 0.2154 0.3825
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0004 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0004 0.0002
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0215 0.0122 0.0217
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0047
Echinococcus granulosus F box protein 36 0.0045 0.0018 0.0032
Schistosoma mansoni pyruvate kinase 0.0019 0.0002 0.0004
Leishmania major pyruvate kinase 0.0037 0.0013 0.005
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0024 0.0022
Brugia malayi putative neuropeptide receptor NPR1 0.0201 0.0114 0.0857
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Brugia malayi GGL domain containing protein 0.0919 0.0555 0.4185
Treponema pallidum fructose-bisphosphate aldolase 0.0324 0.019 0.1476
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0015 0.0026
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0001 0.0009
Leishmania major mitochondrial DNA polymerase beta 0.0333 0.0195 0.0787
Loa Loa (eye worm) hypothetical protein 0.168 0.1023 0.771
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0013 0.0092
Echinococcus granulosus rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0465 0.0277 0.0491
Brugia malayi Dopamine receptor protein 2 0.0201 0.0114 0.0857
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0201 0.0114 0.0202
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0017 0.0316
Leishmania major DNA polymerase kappa, putative 0.0021 0.0004 0.0011
Onchocerca volvulus 0.0201 0.0114 0.0627
Onchocerca volvulus 0.0053 0.0023 0.0125
Schistosoma mansoni ap endonuclease 0.004 0.0015 0.0027
Loa Loa (eye worm) plexin A 0.0084 0.0042 0.0317
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0027 0.0048
Echinococcus granulosus zinc finger protein 0.0029 0.0008 0.0015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0126 0.0068 0.0553
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0055 0.0024 0.0183
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.019 0.0188
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0807 0.0487 0.3668
Echinococcus multilocularis lipoxygenase domain containing protein 0.0061 0.0028 0.005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0015 0.0014
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0004 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0019 0.0139
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0022 0.0039
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0013 0.0072
Brugia malayi G protein-coupled receptor 0.0201 0.0114 0.0857
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0018 0.0002 0.0003
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.2175 0.1327 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.0024 0.0042
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.005 0.0021 0.0164
Echinococcus granulosus tm gpcr rhodopsin 0.0201 0.0114 0.0202
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Brugia malayi PHD-finger family protein 0.0016 0 0.0003
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0201 0.0114 0.0202
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0201 0.0114 0.0202
Echinococcus granulosus rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0201 0.0114 0.0202
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0004 0.0002
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0027 0.0048
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0011 0.008
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0013 0.0036
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0065
Schistosoma mansoni 23-cyclic-nucleotide 2-phosphodiesterase 0.1964 0.1198 0.2127
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0173 0.0097 0.0728
Schistosoma mansoni hypothetical protein 0.003 0.0009 0.0015
Echinococcus multilocularis G-protein coupled receptor, putative 0.0201 0.0114 0.0202
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0004 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0201 0.0114 0.0202
Echinococcus granulosus neuropeptide Y receptor 0.0201 0.0114 0.0202
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0004 0.0002
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0094 0.0048 0.039
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.005 0.0021 0.067
Schistosoma mansoni semaphorin 5-related 0.003 0.0009 0.0015
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0238 0.0137 0.0243
Echinococcus granulosus carbonic anhydrase 0.0807 0.0487 0.0865
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0001 0.0002
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0017 0.0312
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0001 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0021 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0011 0.008
Schistosoma mansoni cytochrome P450 0.0022 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.0011 0.008
Trichomonas vaginalis adenosine diphosphatase, putative 0.0094 0.0048 0.0047
Brugia malayi RE15519p 0.0201 0.0114 0.0857
Plasmodium vivax multidomain scavenger receptor, putative 0.0061 0.0028 0.0942
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0201 0.0114 0.0202
Schistosoma mansoni lipoxygenase 0.0238 0.0137 0.0243
Brugia malayi cytochrome P450 0.0022 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0045 0.0018 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0027 0.0048
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.0011 0.008
Echinococcus granulosus g protein coupled receptor 0.0201 0.0114 0.0202
Schistosoma mansoni zinc finger protein 0.0017 0.0001 0.0001
Mycobacterium leprae conserved hypothetical protein 0.005 0.0021 0.0071
Schistosoma mansoni hypothetical protein 0.0053 0.0023 0.0041
Echinococcus granulosus neuropeptides capa receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0018 0.0032
Brugia malayi SET domain containing protein 0.0016 0.0001 0.0004
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0004 0.0033
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0045 0.0018 0.0032
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0015 0.0014
Echinococcus granulosus transcription factor Dp 1 0.0124 0.0067 0.0119
Brugia malayi G-protein coupled receptor 0.0201 0.0114 0.0857
Brugia malayi hypothetical protein 0.0061 0.0028 0.0212
Echinococcus granulosus tachykinin peptides receptor 99D 0.0201 0.0114 0.0202
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0201 0.0114 0.0627
Schistosoma mansoni rab6-interacting 0.0061 0.0028 0.005
Echinococcus granulosus neuropeptide Y receptor 0.0201 0.0114 0.0202
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0023 0.004
Mycobacterium ulcerans hypothetical protein 0.0175 0.0098 0.0096
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0012 0.0022
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0009
Loa Loa (eye worm) hypoxia-induced factor 1 0.0159 0.0088 0.0666
Trypanosoma brucei Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0473 0.0281 0.2113
Echinococcus multilocularis neuropeptides capa receptor 0.0201 0.0114 0.0202
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.0024 0.0042
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0187 0.0106 0.0104
Schistosoma mansoni pyruvate kinase 0.0037 0.0013 0.0023
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.001 0.0077
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.005 0.0021 0.0701
Brugia malayi Sema domain containing protein 0.003 0.0009 0.0065
Brugia malayi chromobox protein homolog 3 0.0043 0.0017 0.0127
Echinococcus granulosus survival motor neuron protein 1 0.026 0.0151 0.0267
Echinococcus granulosus rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0179 0.01 0.0757
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0015 0.0013
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0007 0.0004
Echinococcus multilocularis p2X purinoceptor 4 0.9174 0.5631 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.019 0.0188
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0024 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0201 0.0114 0.0202
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0021 0.0162
Schistosoma mansoni histamine h1 receptor 0.0201 0.0114 0.0202
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0004 0.0012
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0004 0.0002
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0004 0.0024
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0121 0.0065 0.0491
Brugia malayi Kringle domain containing protein 0.0023 0.0005 0.0036
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0121 0.0065 0.0116
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0004 0.0002
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0015 0.0116
Echinococcus multilocularis neuropeptide receptor A26 0.0707 0.0425 0.0755
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0004 0.0002
Loa Loa (eye worm) MBCTL1 0.006 0.0027 0.0205
Trypanosoma brucei phosphoglycerate kinase 0.0069 0.0033 0.0241
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0024 0.0182
Brugia malayi Sema domain containing protein 0.003 0.0009 0.0065
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0121 0.0065 0.0063
Brugia malayi acetyltransferase, GNAT family protein 0.0163 0.0091 0.0685
Echinococcus multilocularis G protein coupled receptor 139 0.0201 0.0114 0.0202
Echinococcus granulosus semaphorin 1A 0.003 0.0009 0.0015
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0004 0.0001
Leishmania major carbonic anhydrase family protein, putative 0.4028 0.2467 1
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0014
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.003 0.0032
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0158 0.0088 0.0341
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0007 0.0004
Brugia malayi CXXC zinc finger family protein 0.0062 0.0028 0.0214
Schistosoma mansoni neuropeptide F-like receptor 0.0201 0.0114 0.0202
Schistosoma mansoni neuropeptide receptor 0.0201 0.0114 0.0202
Leishmania major phosphopantetheinyl transferase-like protein 0.005 0.0021 0.0083
Brugia malayi Cytochrome P450 family protein 0.0022 0.0004 0.003
Schistosoma mansoni amine GPCR 0.0201 0.0114 0.0202
Echinococcus granulosus rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0007 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0014
Loa Loa (eye worm) inositol-1 0.0041 0.0015 0.0117
Echinococcus granulosus tm gpcr rhodopsin 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0018 0.0002 0.001
Loa Loa (eye worm) TK/ROR protein kinase 0.0027 0.0007 0.0052
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.005 0.0021 0.0164
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0082 0.0041 0.0163
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0011 0.0019
Schistosoma mansoni ap endonuclease 0.004 0.0015 0.0027
Echinococcus multilocularis zinc finger protein 0.0029 0.0008 0.0015
Echinococcus multilocularis p2X purinoceptor 4 0.9174 0.5631 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.001 0.0018
Echinococcus multilocularis carbonic anhydrase II 0.2175 0.1327 0.2357
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0201 0.0114 0.0857
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.003 0.0053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.019 0.0188
Schistosoma mansoni hypothetical protein 0.0041 0.0016 0.0028
Schistosoma mansoni inositol monophosphatase 0.0041 0.0015 0.0027
Brugia malayi nuclear receptor RXR 0.0017 0.0001 0.0009
Loa Loa (eye worm) hypothetical protein 0.006 0.0027 0.0205
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0015 0.0109
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0008 0.0014
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0007 0.0049
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0011 0.0019
Echinococcus granulosus 3'partial|ectonucleoside triphosphate diphosphohydrolase 0.0648 0.0389 0.0691
Leishmania major nucleoside phosphatase, putative,guanosine diphosphatase, putative 0.0094 0.0048 0.0193
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0094 0.0048 0.0047
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0009
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Brugia malayi hypothetical protein 0.003 0.0009 0.0065
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0011 0.008
Trypanosoma cruzi nucleoside phosphatase, putative 0.0094 0.0048 0.0359
Brugia malayi G protein-coupled receptor F59B2.13 0.0201 0.0114 0.0857
Loa Loa (eye worm) G-protein coupled receptor 0.0201 0.0114 0.0857
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0015 0.0027
Echinococcus multilocularis guanine nucleotide binding protein subunit beta 0.0045 0.0018 0.0032
Brugia malayi Phosphoglycerate kinase 0.0069 0.0033 0.0247
Brugia malayi PHD-finger family protein 0.0032 0.001 0.0077
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0004 0.0006
Giardia lamblia DINP protein human, muc B family 0.0021 0.0004 0.0031
Plasmodium vivax sulfate transporter, putative 0.0473 0.0281 1
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0024 0.0042
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0024 0.0042
Echinococcus multilocularis RUN 0.0061 0.0028 0.005
Echinococcus granulosus Polycystic kidney disease protein 0.0061 0.0028 0.005
Echinococcus granulosus p2X purinoceptor 4 0.9174 0.5631 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0034 0.0257
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.008
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0004 0.0013
Echinococcus multilocularis orexin receptor type 2 0.0201 0.0114 0.0202
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0015 0.0114
Trichomonas vaginalis adenosine/guanosine diphosphatase, putative 0.0094 0.0048 0.0047
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.0011 0.0019
Loa Loa (eye worm) acetyltransferase 0.0163 0.0091 0.0685
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0069 0.0033 0.0241
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0049
Loa Loa (eye worm) carbonic anhydrase 3 0.2175 0.1327 1
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0013 0.0011
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0015 0.0015
Brugia malayi Bromodomain containing protein 0.0046 0.0019 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0024 0.0022
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0018 0.0134
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0082 0.0041 0.0303
Trichomonas vaginalis adenosine diphosphatase, putative 0.0094 0.0048 0.0047
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.005 0.0021 0.0404
Echinococcus granulosus neuropeptide FF receptor 2 0.0201 0.0114 0.0202
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0187 0.0106 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0021 0.0038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0015 0.0109
Loa Loa (eye worm) hypothetical protein 0.0061 0.0028 0.0212
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0015 0.0485
Giardia lamblia Pyruvate kinase 0.0037 0.0013 0.0228
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0201 0.0114 0.0857
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0004 0.0006
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0179 0.01 0.0178
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0007 0.0024
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0015 0.0014
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0013 0.0403
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0012 0.0087
Echinococcus multilocularis survival motor neuron protein 1 0.026 0.0151 0.0267
Echinococcus multilocularis peregrin 0.0049 0.0021 0.0037
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0807 0.0487 0.3668
Echinococcus multilocularis biogenic amine (5HT) receptor 0.3519 0.2154 0.3825
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0073 0.0129
Echinococcus granulosus alpha 1A adrenergic receptor 0.0201 0.0114 0.0202
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Echinococcus granulosus microtubule associated protein 2 0.076 0.0458 0.0813
Echinococcus granulosus biogenic amine 5HT receptor 0.168 0.1023 0.1818
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0094 0.0048 0.0086
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0201 0.0114 0.0857
Onchocerca volvulus 0.0201 0.0114 0.0627
Brugia malayi Phosphoglycerate kinase 0.0187 0.0106 0.0796
Schistosoma mansoni inositol monophosphatase 0.0041 0.0015 0.0027
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0473 0.0281 0.2113
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.0011 0.0019
Onchocerca volvulus Alhambra homolog 0.0032 0.001 0.0056
Brugia malayi ORL1-like opioid receptor 0.0201 0.0114 0.0857
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0324 0.019 0.0767
Schistosoma mansoni hypothetical protein 0.0022 0.0004 0.0007
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0013 0.0098
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0007 0.0004
Echinococcus multilocularis lipoxygenase domain containing protein 0.0061 0.0028 0.005
Leishmania major cathepsin L-like protease 0.007 0.0034 0.0133
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni neuropeptide receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0015 0.011
Brugia malayi neuropeptide F receptor 0.0201 0.0114 0.0857
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.003 0.0118
Echinococcus multilocularis pyruvate kinase 0.0037 0.0013 0.0023
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0201 0.0114 0.0202
Schistosoma mansoni hypothetical protein 0.0328 0.0192 0.0341
Onchocerca volvulus 0.0018 0.0002 0.001
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0021 0.0162
Brugia malayi Melatonin receptor type 1A 0.0201 0.0114 0.0857
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0011 0.0019
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0018 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0048 0.0047
Echinococcus multilocularis 0.0022 0.0004 0.0007
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0034 0.0011 0.0084
Schistosoma mansoni biogenic amine receptor 0.0201 0.0114 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0024 0.0042
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0087 0.035
Onchocerca volvulus 0.0201 0.0114 0.0627
Schistosoma mansoni jumonji domain containing protein 0.0084 0.0042 0.0074
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0893 0.054 0.0958
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0027 0.0205
Echinococcus granulosus semaphorin 5B 0.003 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0187 0.0106 0.012
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.008
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0215 0.0123 0.0218
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0021 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0201 0.0114 0.0202
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0014
Brugia malayi Pre-SET motif family protein 0.0232 0.0133 0.1002
Brugia malayi jmjC domain containing protein 0.0105 0.0055 0.0415
Schistosoma mansoni hypothetical protein 0.0032 0.001 0.0018
Brugia malayi Cytochrome P450 family protein 0.0031 0.001 0.0073
Echinococcus multilocularis plexin a4 0.0084 0.0042 0.0075
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0105 0.0055 0.0098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Leishmania major cytochrome p450-like protein 0.0031 0.001 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.0011 0.008
Echinococcus granulosus dna polymerase eta 0.0049 0.0021 0.0037
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0201 0.0114 0.0202
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0024 0.0022
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0001 0.0002
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0001 0.0002
Schistosoma mansoni myosin xvIII 0.0201 0.0114 0.0202
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0034 0.0248
Toxoplasma gondii inorganic anion transporter, sulfate permease (SulP) family protein 0.0473 0.0281 0.2335
Echinococcus granulosus dnaJ subfamily B 0.0426 0.0252 0.0448
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0019 0.0139
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0004 0.0001
Schistosoma mansoni hypothetical protein 0.0426 0.0252 0.0448
Echinococcus multilocularis pyruvate kinase 0.0019 0.0002 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0807 0.0487 0.3668
Schistosoma mansoni neuropeptide f receptor 76f 0.0201 0.0114 0.0202
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0014
Echinococcus multilocularis allatostatin A receptor 0.0201 0.0114 0.0202
Echinococcus granulosus single minded 2 0.0038 0.0014 0.0025
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0121 0.0065 0.0116
Brugia malayi mbt repeat family protein 0.0053 0.0023 0.0172
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0013 0.0072
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0003
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0004 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0024 0.0182
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0002 0.0005
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0201 0.0114 0.0857
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0015 0.0109
Mycobacterium ulcerans phosphoglycerate kinase 0.0187 0.0106 0.0103
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.003 0.0219
Treponema pallidum phosphoglycerate kinase 0.0187 0.0106 0.0764
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0023 0.0172
Echinococcus multilocularis dnaJ subfamily B 0.0426 0.0252 0.0448
Echinococcus granulosus carbonic anhydrase II 0.2175 0.1327 0.2357
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0004 0.0002
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.005 0.0021 0.0019
Onchocerca volvulus 0.002 0.0003 0.0014
Schistosoma mansoni cpg binding protein 0.0067 0.0032 0.0057
Schistosoma mansoni phd finger protein 0.0017 0.0001 0.0002
Onchocerca volvulus 0.0018 0.0002 0.001
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.188 0.1146 0.1319
Schistosoma mansoni chromobox protein 0.0077 0.0038 0.0067
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0039 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0065
Loa Loa (eye worm) hypothetical protein 0.0123 0.0066 0.0497
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.002
Brugia malayi nuclear hormone receptor 0.0033 0.0011 0.008
Echinococcus granulosus allatostatin A receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0035 0.0063
Loa Loa (eye worm) cytochrome P450 0.0022 0.0004 0.003
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0004 0.0007
Onchocerca volvulus 0.0201 0.0114 0.0627
Echinococcus granulosus phosphoglycerate kinase 1 0.0187 0.0106 0.0188
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0054 0.0024 0.018
Plasmodium vivax SET domain protein, putative 0.0035 0.0012 0.0374
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0002 0.0014
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0807 0.0487 0.3668
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0004 0.0002
Trichomonas vaginalis adenosine diphosphatase, putative 0.0094 0.0048 0.0047
Echinococcus granulosus sex peptide receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0049 0.0021 0.0157
Onchocerca volvulus 0.0201 0.0114 0.0627
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0004 0.0002
Entamoeba histolytica hypothetical protein 0.0045 0.0018 0.0071
Brugia malayi hypoxia-induced factor 1 0.0159 0.0088 0.0666
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0807 0.0487 0.3668
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0121 0.0065 0.0116
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0013 0.0092
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0201 0.0114 0.0202
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0015 0.0026
Echinococcus multilocularis microtubule associated protein 2 0.076 0.0458 0.0813
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0004 0.0002
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0201 0.0114 0.0857
Loa Loa (eye worm) neuropeptide F receptor 0.0201 0.0114 0.0857
Schistosoma mansoni cpg binding protein 0.0062 0.0028 0.0051
Echinococcus multilocularis neuropeptide s receptor 0.0707 0.0425 0.0755
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0031 0.0235
Schistosoma mansoni amine GPCR 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0004 0.0024
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0002 0.0004
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0121 0.0065 0.0261
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.0011 0.0019
Loa Loa (eye worm) neuropeptide F receptor 0.0201 0.0114 0.0857
Loa Loa (eye worm) cysteine protease 0.0018 0.0002 0.0014
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0004 0.002
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0021 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0009 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0007 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0024 0.0042
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0004 0.002
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.0011 0.0019
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0014
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0002 0.0004
Schistosoma mansoni survival motor neuron protein 0.0053 0.0023 0.0041
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.5576 0.3418 0.3937
Schistosoma mansoni plexin 0.0071 0.0034 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.019 0.0188
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0003
Echinococcus multilocularis GPCR, family 2 0.0017 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0011 0.008
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0021 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0121 0.0065 0.0063
Schistosoma mansoni bromodomain containing protein 0.0077 0.0038 0.0067
Loa Loa (eye worm) G-protein coupled receptor 0.0201 0.0114 0.0857
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.0011 0.0019
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0215 0.0123 0.0218
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0019 0.0139
Onchocerca volvulus 0.0201 0.0114 0.0627
Brugia malayi Dopamine receptor 0.0201 0.0114 0.0857
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Schistosoma mansoni hypothetical protein 0.0201 0.0114 0.0202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.0011 0.008
Loa Loa (eye worm) hypothetical protein 0.0054 0.0024 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0048 0.0047
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.0011 0.0019
Schistosoma mansoni pyruvate kinase 0.0037 0.0013 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0034 0.0248
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0011 0.0019
Brugia malayi Nucleoside-diphosphatase mig-23 0.0094 0.0048 0.0365
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0007 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0007 0.0004
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0024 0.0092
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.001 0.0073
Echinococcus granulosus guanine nucleotide binding protein subunit beta 0.0045 0.0018 0.0032
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0002 0.0024
Brugia malayi MAP kinase sur-1 0.0054 0.0024 0.0178
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0034 0.0248
Echinococcus granulosus dna polymerase kappa 0.0021 0.0004 0.0006
Echinococcus multilocularis neuropeptide FF receptor 2 0.0201 0.0114 0.0202
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0018 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 1.6282 1 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0215 0.0122 0.0917
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.011 0.0058 0.0435
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.002
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0048 0.002 0.0035
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0014 0.0105
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0201 0.0114 0.0857
Schistosoma mansoni single-minded 0.0051 0.0022 0.0039
Entamoeba histolytica phosphoglycerate kinase, putative 0.0187 0.0106 0.0426
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.0011 0.0019
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0004 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0201 0.0114 0.0627
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0019
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0 0.0001
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0094 0.0048 0.0086
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.2175 0.1327 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0003
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.2175 0.1327 1
Trypanosoma brucei nucleoside phosphatase, putative 0.0094 0.0048 0.0359
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.001 0.0018
Echinococcus multilocularis chromobox protein 1 0.0077 0.0038 0.0067
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0018 0.0002 0.0003
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0187 0.0106 0.0413
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0013 0.0092
Echinococcus multilocularis p2X purinoceptor 4 0.9174 0.5631 1
Schistosoma mansoni hypothetical protein 0.0023 0.0005 0.0009
Brugia malayi G-protein coupled receptor 0.0201 0.0114 0.0857
Trypanosoma brucei phosphoglycerate kinase 0.0187 0.0106 0.0791
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0013 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0004 0.0002
Schistosoma mansoni opsin-like receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0238 0.0137 0.0243
Schistosoma mansoni 23-cyclic-nucleotide 2-phosphodiesterase 0.1958 0.1194 0.2121
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0024 0.0182
Onchocerca volvulus 0.0026 0.0007 0.0036
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni carbonic anhydrase-related 0.0807 0.0487 0.0865
Loa Loa (eye worm) hypothetical protein 0.0179 0.01 0.0757
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0008 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0007 0.0023
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0201 0.0114 0.0857
Loa Loa (eye worm) GTP-binding regulatory protein beta chain 0.0045 0.0018 0.0136
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0215 0.0122 0.0493
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis neuropeptide receptor 0.0201 0.0114 0.0202
Echinococcus granulosus p2X purinoceptor 4 0.9174 0.5631 1
Plasmodium falciparum pyruvate kinase 0.0037 0.0013 0.0232
Echinococcus multilocularis pyruvate kinase 0.0037 0.0013 0.0023
Echinococcus multilocularis serotonin receptor 0.168 0.1023 0.1818
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0019 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0201 0.0114 0.0202
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0001 0.0009
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0024 0.0092
Brugia malayi Serotonin receptor 0.0201 0.0114 0.0857
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0024 0.0042
Loa Loa (eye worm) TYRA-2 protein 0.0201 0.0114 0.0857
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0324 0.019 0.0188
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis fmrfamide receptor 0.0201 0.0114 0.0202
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.4028 0.2467 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0015 0.0279
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0024 0.0042
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0158 0.0088 0.0099
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0007 0.0049
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0024 0.0172
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0013 0.0037
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0023 0.0125
Echinococcus multilocularis neuropeptide Y receptor 0.0201 0.0114 0.0202
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0021 0.0155
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0201 0.0114 0.0202
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0187 0.0106 0.0791
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0001 0.0002
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0024 0.0447
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0215 0.0122 0.0923
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0069 0.0033 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Onchocerca volvulus 0.003 0.0009 0.0048
Leishmania major phosphoglycerate kinase C, glycosomal 0.0187 0.0106 0.0425
Brugia malayi Protein kinase domain containing protein 0.0027 0.0007 0.0052
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0019
Echinococcus granulosus neuropeptide receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0201 0.0114 0.0202
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.0011 0.0019
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0002 0.0014
Schistosoma mansoni cpg binding protein 0.0067 0.0032 0.0057
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0007 0.0005
Brugia malayi sulfakinin receptor protein 0.0201 0.0114 0.0857
Trichomonas vaginalis protein phosphatase type 2C, putative 0.0123 0.0066 0.0064
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0002 0.0014
Echinococcus multilocularis dro:myosuppressin receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0016 0 0.0003
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0015 0.0027
Echinococcus granulosus neuropeptide receptor 0.0201 0.0114 0.0202
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.003 0.0028
Giardia lamblia Phosphoglycerate kinase 0.0187 0.0106 0.215
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0002 0.001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0215 0.0122 0.0917
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0004 0.002
Entamoeba histolytica carbonic anhydrase, putative 0.4028 0.2467 1
Schistosoma mansoni microtubule-associated protein tau 0.076 0.0458 0.0813
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0049
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0014 0.0026
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0201 0.0114 0.0202
Trypanosoma brucei phosphoglycerate kinase 0.0187 0.0106 0.0791
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0004 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0201 0.0114 0.0202
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.0011 0.0019
Trichomonas vaginalis set domain proteins, putative 0.0263 0.0152 0.0151
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0013 0.0098
Loa Loa (eye worm) sema domain-containing protein 0.003 0.0009 0.0065
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0028 0.0214
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0201 0.0114 0.0202
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0004 0.0002
Onchocerca volvulus 0.0071 0.0034 0.0188
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.001 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0017 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0001 0.0009
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0215 0.0122 0.0217
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus multilocularis transcription factor Dp 1 0.0124 0.0067 0.0119
Mycobacterium tuberculosis Beta-carbonic anhydrase 1.4133 0.8679 1
Echinococcus multilocularis g-protein coupled receptor 0.0201 0.0114 0.0202
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0013 0.0011
Leishmania major carbonic anhydrase-like protein 0.2175 0.1327 0.5379
Brugia malayi hypothetical protein 0.026 0.0151 0.1134
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Echinococcus granulosus fmrfamide receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0201 0.0114 0.0202
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0163 0.0091 0.0161
Echinococcus multilocularis pyruvate kinase 0.0019 0.0002 0.0004
Onchocerca volvulus 0.0263 0.0152 0.084
Mycobacterium ulcerans integral membrane transporter 0.0473 0.0281 0.0279
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0002 0.0001
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0015 0.0027
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0015 0.0059
Brugia malayi hypothetical protein 0.0201 0.0114 0.0857
Schistosoma mansoni growth hormone secretagogue receptor 0.0201 0.0114 0.0202
Echinococcus multilocularis g protein coupled receptor 0.0201 0.0114 0.0202
Echinococcus granulosus pyruvate kinase 0.0037 0.0013 0.0023
Echinococcus multilocularis chromobox protein 1 0.0077 0.0038 0.0067
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.0011 0.0019
Loa Loa (eye worm) ctsf protein 0.0018 0.0002 0.0014
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0002
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0001 0.0009
Brugia malayi ecdysteroid receptor 0.0033 0.0011 0.008
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0005 0.0037
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0021 0.0019
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0003
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0001 0.0002
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.003 0.0235
Echinococcus granulosus L aminoadipate semialdehyde 0.0179 0.01 0.0178
Schistosoma mansoni adenoreceptor 0.0201 0.0114 0.0202
Treponema pallidum 4'-phosphopantetheinyl transferase 0.005 0.0021 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0004 0.0002
Leishmania major cathepsin L-like protease 0.007 0.0034 0.0133
Echinococcus granulosus tissue type plasminogen activator 0.0023 0.0005 0.0009
Schistosoma mansoni hypothetical protein 0.0061 0.0028 0.005
Onchocerca volvulus 0.0201 0.0114 0.0627
Brugia malayi CHD4 protein 0.0018 0.0002 0.0012
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0094 0.0048 0.039
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0008 0.0014
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.0006 0.0023
Schistosoma mansoni hypothetical protein 0.0201 0.0114 0.0202
Schistosoma mansoni alpha-1 adrenergic receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0201 0.0114 0.0857
Echinococcus multilocularis carbonic anhydrase 0.0807 0.0487 0.0865
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0024 0.0172
Plasmodium falciparum cysteine repeat modular protein 1 0.0023 0.0005 0.0062
Loa Loa (eye worm) GGL domain-containing protein 0.0919 0.0555 0.4185
Loa Loa (eye worm) hypothetical protein 0.0042 0.0016 0.0124
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0021 0.015
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0009 0.0007
Echinococcus multilocularis F box protein 36 0.0045 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0065
Onchocerca volvulus 0.0061 0.0028 0.0155
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0004 0.0002
Mycobacterium ulcerans carbonic anhydrase 0.4028 0.2467 0.2465
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0201 0.0114 0.0857
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0015 0.0059
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0019
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0004 0.0006
Echinococcus multilocularis carbonic anhydrase 0.0807 0.0487 0.0865
Loa Loa (eye worm) hypothetical protein 0.0807 0.0487 0.3668
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0013 0.0092
Leishmania major cytochrome p450-like protein 0.0022 0.0004 0.0013
Schistosoma mansoni hypothetical protein 0.0201 0.0114 0.0202
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.008
Loa Loa (eye worm) sema domain-containing protein 0.003 0.0009 0.0065
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0014 0.0102
Schistosoma mansoni amine GPCR 0.0201 0.0114 0.0202
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0 0.0001
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0021 0.0692
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0094 0.0048 0.0047
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0027 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.0011 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0048 0.002 0.011
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0333 0.0195 0.1463
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.0011 0.008
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.001 0.007
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Echinococcus granulosus pyruvate kinase 0.0019 0.0002 0.0004
Schistosoma mansoni opsin-like receptor 0.0201 0.0114 0.0202
Loa Loa (eye worm) hypothetical protein 0.0055 0.0024 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.002
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Echinococcus granulosus rhodopsin orphan GPCR 0.0201 0.0114 0.0202
Onchocerca volvulus 0.0018 0.0002 0.001
Schistosoma mansoni hypothetical protein 0.0807 0.0487 0.0865

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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