Detailed information for compound 913966

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 603.727 | Formula: C34H42FN5O4
  • H donors: 3 H acceptors: 4 LogP: 4.34 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCC[C@@H]1N(CCN(C1=O)[C@H](C(=O)NC)Cc1ccc2c(c1)cccc2)C(=O)[C@H](NC(=O)[C@@H](NC)C)Cc1ccc(cc1)F
  • InChi: 1S/C34H42FN5O4/c1-5-8-29-34(44)40(30(32(42)37-4)21-24-11-14-25-9-6-7-10-26(25)19-24)18-17-39(29)33(43)28(38-31(41)22(2)36-3)20-23-12-15-27(35)16-13-23/h6-7,9-16,19,22,28-30,36H,5,8,17-18,20-21H2,1-4H3,(H,37,42)(H,38,41)/t22-,28+,29-,30-/m0/s1
  • InChiKey: AHYGIWNTGDKMRR-SUAIOLNFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) Starlite/ChEMBL References
Homo sapiens melanocortin 4 receptor Starlite/ChEMBL References
Homo sapiens melanocortin 3 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi beta-tubulin, identical Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium yoelii tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-7 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta-4 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin alpha chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei gambiense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Theileria parva tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii beta-1 tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium hominis beta-catenin-like repeat protein Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma cruzi beta tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium vivax tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin beta 1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin, beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-1 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum ko:K07375 tubulin beta, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma congolense beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin gamma chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Babesia bovis tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania braziliensis beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Toxoplasma gondii beta-tubulin, putative Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus tubulin beta 4A class IVa Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Brugia malayi Tubulin beta-1 chain Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta-4 chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania infantum beta-tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) BEN-1 protein Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma japonicum Tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
Trypanosoma brucei beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Schistosoma mansoni tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania major beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Giardia lamblia Beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Cryptosporidium parvum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis tubulin subunit beta Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus granulosus Tubulin beta 2C chain Get druggable targets OG5_126611 All targets in OG5_126611
Entamoeba histolytica tubulin family protein Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium falciparum tubulin beta chain Get druggable targets OG5_126611 All targets in OG5_126611
Loa Loa (eye worm) tubulin beta-2A chain Get druggable targets OG5_126611 All targets in OG5_126611
Echinococcus multilocularis beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Neospora caninum hypothetical protein Get druggable targets OG5_126611 All targets in OG5_126611
Leishmania mexicana beta tubulin Get druggable targets OG5_126611 All targets in OG5_126611
Plasmodium berghei tubulin beta chain, putative Get druggable targets OG5_126611 All targets in OG5_126611
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus glycine receptor subunit beta 0.0043 0.0038 0.0038
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0028 0.0028
Onchocerca volvulus 0.0077 0.0085 0.0558
Loa Loa (eye worm) BEN-1 protein 0.0027 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Onchocerca volvulus 0.0031 0.0021 0.011
Onchocerca volvulus 0.0043 0.0038 0.0227
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0057 0.0058 0.0684
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Toxoplasma gondii fructose-bisphospatase II 0.714 1 1
Schistosoma mansoni fructose-16-bisphosphatase-related 0.714 1 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0195 0.0251 0.2974
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.064 0.0875 0.0875
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Schistosoma mansoni cpg binding protein 0.0035 0.0026 0.0026
Echinococcus multilocularis tumor protein p63 0.0741 0.1017 0.1017
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Echinococcus granulosus neuropeptide s receptor 0.0081 0.0092 0.0092
Toxoplasma gondii ABC1 family protein 0.0077 0.0085 0.0085
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0057 0.0058 0.0684
Echinococcus granulosus dnaJ subfamily B 0.0444 0.06 0.06
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0081 0.0092 0.0092
Entamoeba histolytica acyl-CoA synthetase, putative 0.0195 0.0251 1
Loa Loa (eye worm) amidase 0.0065 0.0068 0.0065
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.0018 0.0018
Loa Loa (eye worm) tubulin beta-2A chain 0.0027 0.0016 0.0012
Trichomonas vaginalis antibiotic synthetase, putative 0.0057 0.0058 0.0684
Onchocerca volvulus 0.0107 0.0128 0.0856
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.003 0.1659
Entamoeba histolytica hypothetical protein 0.0115 0.0139 0.5398
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0007 0.0007
Onchocerca volvulus Phospholipase A2 homolog 0.0431 0.0583 0.4027
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0127 0.1897
Schistosoma mansoni neurotransmitter gated ion channel 0.0023 0.001 0.001
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0077 0.0086 0.0083
Loa Loa (eye worm) hypothetical protein 0.0431 0.0583 0.0579
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0045 0.0533
Echinococcus multilocularis Niemann Pick C1 protein 0.0112 0.0135 0.0135
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0009 0.0009
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0007 0.0003
Leishmania major 4-coumarate:coa ligase-like protein 0.0195 0.0251 0.0251
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0212
Echinococcus granulosus microtubule associated protein 2 0.1428 0.1982 0.1982
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0127 0.1897
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.002 0.002
Brugia malayi Bromodomain containing protein 0.0037 0.0029 0.0029
Onchocerca volvulus 0.0081 0.0092 0.0603
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0041 0.0041
Schistosoma mansoni neuropeptide receptor 0.0081 0.0092 0.0092
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0081 0.0092 0.0092
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0081 0.0092 0.0092
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0057 0.0058 0.0058
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0034 0.0034
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0007 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0004 0.0067
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0038 0.0038
Echinococcus granulosus neuropeptide FF receptor 2 0.0081 0.0092 0.0092
Brugia malayi putative amidase 0.0065 0.0068 0.0068
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Echinococcus granulosus nAChR subunit 0.0043 0.0038 0.0038
Entamoeba histolytica tubulin family protein 0.0027 0.0016 0.0371
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0086 0.1023
Echinococcus granulosus beta tubulin 0.0027 0.0016 0.0016
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0127 0.1897
Echinococcus granulosus flap endonuclease 1 0.003 0.0019 0.0019
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.003 0.003
Schistosoma mansoni cpg binding protein 0.0031 0.0021 0.0021
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0043 0.0038 0.0038
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0008 0.0004
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0043 0.0038 0.0038
Trypanosoma brucei mitochondrial DNA polymerase beta 0.064 0.0875 0.0875
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0005
Plasmodium vivax tubulin beta chain, putative 0.0027 0.0016 0.0862
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0078 0.0086 0.0083
Trichomonas vaginalis maltase-glucoamylase, putative 0.0029 0.0018 0.0212
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0081 0.0092 0.0092
Onchocerca volvulus Putative nachr subunit 0.0113 0.0136 0.0912
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0081 0.0092 0.0092
Schistosoma mansoni adenoreceptor 0.0081 0.0092 0.0092
Schistosoma mansoni nAChR subunit 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.0081 0.0092 0.0088
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0057 0.0058 0.0684
Onchocerca volvulus 0.0081 0.0092 0.0603
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0081 0.0092 0.0092
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Brugia malayi acetyltransferase, GNAT family protein 0.0168 0.0213 0.0213
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Plasmodium falciparum acyl-CoA synthetase 0.0146 0.0182 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0085 0.0082
Onchocerca volvulus 0.0081 0.0092 0.0603
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0081 0.0092 0.0092
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0018 0.0018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.007 0.007
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0058 0.0684
Brugia malayi jmjC domain containing protein 0.0099 0.0116 0.0116
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Echinococcus multilocularis neuropeptide receptor 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0085 0.1279
Schistosoma mansoni flap endonuclease-1 0.0027 0.0015 0.0015
Onchocerca volvulus 0.0043 0.0038 0.0227
Echinococcus granulosus neuropeptides capa receptor 0.0081 0.0092 0.0092
Brugia malayi jmjC domain containing protein 0.004 0.0034 0.0034
Onchocerca volvulus 0.0113 0.0136 0.0912
Loa Loa (eye worm) hypothetical protein 0.0077 0.0085 0.0082
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0092 0.0092
Trypanosoma brucei trypanothione reductase 0.0047 0.0043 0.0043
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0049 0.0581
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0085 0.0085
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0086 0.0086
Plasmodium falciparum lysophospholipase, putative 0.0077 0.0085 0.4696
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0537 0.0731 0.0731
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0043 0.0641
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.714 1 1
Schistosoma mansoni biogenic amine receptor 0.0081 0.0092 0.0092
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.003 0.003
Plasmodium vivax acetyl-CoA synthetase, putative 0.0057 0.0058 0.3173
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0034 0.0408
Mycobacterium ulcerans hypothetical protein 0.0195 0.0251 0.2974
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0007 0.0007
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0043 0.0039
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0043 0.0038 0.0038
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Plasmodium falciparum thioredoxin reductase 0.0047 0.0043 0.2349
Schistosoma mansoni acetylcholine receptor subunit beta 0.002 0.0005 0.0005
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0023 0.001 0.001
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0009 0.0005
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0146 0.0182 0.2727
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0081 0.0092 0.0088
Echinococcus granulosus neutral alpha glucosidase AB 0.0078 0.0086 0.0086
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0004 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0058 0.0684
Schistosoma mansoni alpha-glucosidase 0.0301 0.04 0.04
Brugia malayi Dopamine receptor 0.0081 0.0092 0.0092
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0019 0.0019
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0065 0.0068 0.1024
Mycobacterium ulcerans peptide amidase, GatA 0.0065 0.0068 0.0809
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0015 0.1718
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0086 0.1023
Leishmania major cytochrome p450-like protein 0.0029 0.0018 0.0018
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0537 0.0731 0.0731
Echinococcus multilocularis protein dispatched 1 0.0055 0.0055 0.0055
Schistosoma mansoni myosin xvIII 0.0081 0.0092 0.0092
Echinococcus multilocularis glycine receptor subunit beta 0.0043 0.0038 0.0038
Echinococcus multilocularis RUN 0.0043 0.0037 0.0037
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.0004 0.0053
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0013 0.0013
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0085 0.1279
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0085 0.101
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Schistosoma mansoni DNA polymerase eta 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Brugia malayi hypothetical protein 0.003 0.0019 0.0019
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.0004 0.0053
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0004 0.0067
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0191 0.0245 0.0245
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.003 0.351
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0312 0.0416 0.0412
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0029 0.0018 0.0018
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.009 0.0104 0.0104
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0085 0.101
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0009 0.0009
Leishmania major cytochrome p450-like protein 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0526 0.0716 0.0713
Plasmodium vivax PST-A protein 0.0077 0.0085 0.4696
Echinococcus granulosus zinc finger protein 0.0026 0.0014 0.0014
Loa Loa (eye worm) GABA receptor subunit 0.0023 0.001 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0081 0.0092 0.0092
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0007 0.0007
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0013 0.0013
Echinococcus multilocularis survival motor neuron protein 1 0.0526 0.0716 0.0716
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0034 0.0034
Echinococcus granulosus biogenic amine 5HT receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0043 0.0038 0.0034
Echinococcus granulosus tubulin subunit beta 0.0027 0.0016 0.0016
Schistosoma mansoni amine GPCR 0.0081 0.0092 0.0092
Echinococcus multilocularis neuropeptide receptor A26 0.0081 0.0092 0.0092
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Trichomonas vaginalis esterase, putative 0.0077 0.0085 0.101
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0058 0.0684
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Trypanosoma brucei cytochrome P450, putative 0.0029 0.0018 0.0018
Brugia malayi hydrolase, alpha/beta fold family protein 0.0517 0.0703 0.0703
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0046 0.0043 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0002 0.0002
Schistosoma mansoni amine GPCR 0.0081 0.0092 0.0092
Echinococcus granulosus neuropeptide receptor 0.0081 0.0092 0.0092
Schistosoma mansoni neuropeptide receptor 0.0081 0.0092 0.0092
Echinococcus granulosus allatostatin A receptor 0.0081 0.0092 0.0092
Trypanosoma brucei unspecified product 0.0021 0.0007 0.0007
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0142 0.0176 0.0176
Schistosoma mansoni neuropeptide f receptor 76f 0.0081 0.0092 0.0092
Schistosoma mansoni cpg binding protein 0.0035 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0127 0.4948
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0009 0.0009
Loa Loa (eye worm) T-complex protein 1 0.0024 0.0011 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0092 0.0092
Onchocerca volvulus Phospholipase A2 homolog 0.0091 0.0105 0.0694
Schistosoma mansoni amine GPCR 0.0081 0.0092 0.0092
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0081 0.0092 0.0092
Leishmania major DNA polymerase eta, putative 0.0021 0.0007 0.0007
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0065 0.0068 0.0068
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0168 0.0213 0.0213
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Brugia malayi Kinesin motor domain containing protein 0.0122 0.0149 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0146 0.0182 0.0179
Onchocerca volvulus 0.0043 0.0037 0.0223
Giardia lamblia PHD finger protein 15 0.003 0.002 0.1317
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.011 0.0131 0.0131
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0004 0.0067
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0006
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Loa Loa (eye worm) TYRA-2 protein 0.0081 0.0092 0.0088
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0113 0.0136 0.0136
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0113 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0143 0.2146
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0081 0.0092 0.0092
Leishmania major monoglyceride lipase, putative 0.0077 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0081 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.0081 0.0092 0.0092
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0065 0.0068 0.3753
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Leishmania major mitochondrial DNA polymerase beta 0.064 0.0875 0.0875
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0112 0.0135 0.5248
Loa Loa (eye worm) tubulin beta-1 chain 0.0027 0.0016 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0085 0.101
Onchocerca volvulus 0.0057 0.0058 0.0366
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0004 0.0004
Brugia malayi nuclear hormone receptor 0.0022 0.0009 0.0009
Mycobacterium ulcerans amidase 0.0065 0.0068 0.0809
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0038 0.0038
Loa Loa (eye worm) amidase 0.0065 0.0068 0.0065
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Mycobacterium leprae Probable lipase LipE 0.0077 0.0085 0.3277
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0074 0.0074
Toxoplasma gondii beta-tubulin, putative 0.0027 0.0016 0.0016
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.004 0.1361
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.0208 0.0208
Brugia malayi G protein-coupled receptor 0.0081 0.0092 0.0092
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.0011 0.0011
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Entamoeba histolytica acyl-CoA synthetase, putative 0.0195 0.0251 1
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0057 0.0058 0.0058
Echinococcus granulosus kinesin family 1 0.094 0.1297 0.1297
Onchocerca volvulus 0.0081 0.0092 0.0603
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.0004 0.0053
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0027 0.0016 0.0016
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0049 0.0049
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0077 0.0085 0.1012
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0085 0.1279
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.2655 0.3705 0.3705
Loa Loa (eye worm) CYP4Cod1 0.0029 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0112 0.0135 0.0132
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0034 0.1137
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0019 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Schistosoma mansoni hypothetical protein 0.0107 0.0128 0.0128
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0041 0.0041
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0065 0.0068 0.3753
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0212
Echinococcus multilocularis ankyrin repeat protein 0.0155 0.0194 0.0194
Schistosoma mansoni nAChR subunit 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0004 0.0067
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus granulosus dro:myosuppressin receptor 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Conserved protein 0.0077 0.0085 0.1279
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Loa Loa (eye worm) ACC-1 protein 0.0043 0.0038 0.0034
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0058 0.0865
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0058 0.0865
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0057 0.0058 0.0054
Schistosoma mansoni nAChR subunit 0.0043 0.0038 0.0038
Onchocerca volvulus 0.0202 0.0261 0.1787
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.009 0.0104 0.0104
Mycobacterium tuberculosis Conserved hypothetical protein 0.0337 0.045 0.6751
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0092 0.0092
Onchocerca volvulus 0.0081 0.0092 0.0603
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.0004 0.0053
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0065 0.0068 0.7939
Echinococcus multilocularis fmrfamide receptor 0.0081 0.0092 0.0092
Echinococcus granulosus 7TM GPCR rhodopsin 0.0081 0.0092 0.0092
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0081 0.0092 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0019 0.0015
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0034 0.0034
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0019 0.0015
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) tubulin beta-4 chain 0.0027 0.0016 0.0012
Brugia malayi Bromodomain containing protein 0.0085 0.0096 0.0096
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.003 0.0358
Leishmania major alpha glucosidase II subunit, putative 0.0078 0.0086 0.0086
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0057 0.0058 0.0684
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.0018 0.0463
Trypanosoma brucei glucosidase, putative 0.0078 0.0086 0.0086
Schistosoma mansoni coup transcription factor 0.0022 0.0009 0.0009
Loa Loa (eye worm) G-protein coupled receptor 0.0081 0.0092 0.0088
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.004 0.2681
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0043 0.0037 0.0037
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0086 0.4727
Mycobacterium ulcerans amidase 0.0065 0.0068 0.0809
Mycobacterium tuberculosis Conserved protein 0.0077 0.0085 0.1279
Echinococcus granulosus RUN 0.0043 0.0037 0.0037
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0074 0.0074
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0037 0.0037
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0077 0.0085 0.1012
Loa Loa (eye worm) glutathione reductase 0.0047 0.0043 0.0039
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.002 0.0005 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.0031
Echinococcus multilocularis neuropeptide Y receptor 0.0081 0.0092 0.0092
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0058 0.0684
Schistosoma mansoni acetyl-CoA synthetase 0.0057 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0005
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0041 0.0041
Trypanosoma cruzi beta tubulin, putative 0.0027 0.0016 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0092 0.0092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0009 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0085 0.101
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Echinococcus granulosus histone acetyltransferase KAT2B 0.0161 0.0203 0.0203
Brugia malayi Serotonin receptor 0.0081 0.0092 0.0092
Trypanosoma cruzi monoglyceride lipase, putative 0.0077 0.0085 0.0085
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0093 0.0108 0.0105
Echinococcus granulosus somatostatin receptor 0.0081 0.0092 0.0092
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.002 0.002
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0011 0.0011
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0034 0.0034
Echinococcus multilocularis lysosomal alpha glucosidase 0.035 0.0469 0.0469
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0043 0.0038 0.0034
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0043 0.0038 0.0038
Brugia malayi Cytochrome P450 family protein 0.0019 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0081 0.0092 0.0092
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0195 0.0251 1
Schistosoma mansoni glutaminase 0.0618 0.0844 0.0844
Brugia malayi beta-lactamase 0.0077 0.0085 0.0085
Loa Loa (eye worm) transcription factor SMAD2 0.014 0.0173 0.017
Echinococcus multilocularis Niemann Pick C1 protein 0.016 0.0203 0.0203
Schistosoma mansoni fatty-acid amide hydrolase 0.0537 0.0731 0.0731
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0009 0.0009
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0081 0.0092 0.0092
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0113 0.0136 0.0136
Entamoeba histolytica hypothetical protein 0.0115 0.0139 0.5398
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.0011 0.0011
Brugia malayi Niemann-Pick C1 protein precursor 0.0112 0.0135 0.0135
Schistosoma mansoni alpha-glucosidase 0.0301 0.04 0.04
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0034 0.0408
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0057 0.0058 0.209
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0113 0.0136 0.0133
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0005
Entamoeba histolytica hypothetical protein 0.0115 0.0139 0.5398
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.0011 0.0011
Onchocerca volvulus 0.0081 0.0092 0.0603
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Mycobacterium ulcerans glutaminase 0.0618 0.0844 1
Plasmodium vivax hypothetical protein, conserved 0.003 0.002 0.1077
Onchocerca volvulus 0.0023 0.001 0.0033
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0086 0.1019
Brugia malayi AMP-binding enzyme family protein 0.0195 0.0251 0.0251
Onchocerca volvulus 0.0081 0.0092 0.0603
Mycobacterium ulcerans amidase 0.0065 0.0068 0.0809
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.002 0.002
Onchocerca volvulus Huntingtin homolog 0.0133 0.0164 0.1107
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0092 0.0092
Toxoplasma gondii hypothetical protein 0.0027 0.0015 0.0015
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0019 0.0019
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Brugia malayi sulfakinin receptor protein 0.0081 0.0092 0.0092
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0078 0.0086 0.1023
Schistosoma mansoni rab6-interacting 0.0043 0.0037 0.0037
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0015 0.0418
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0043 0.0038 0.0038
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0009 0.0009
Giardia lamblia Beta tubulin 0.0027 0.0016 0.1055
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0043 0.0038 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0009 0.0009
Trypanosoma cruzi amidase, putative 0.0065 0.0068 0.0068
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.004 0.0034 0.0031
Loa Loa (eye worm) melatonin receptor type 1A 0.0081 0.0092 0.0088
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Schistosoma mansoni cytochrome P450 0.0019 0.0004 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0086 0.1023
Trichomonas vaginalis tubulin, putative 0.0027 0.0016 0.0186
Loa Loa (eye worm) LGC-31 protein 0.0043 0.0038 0.0034
Schistosoma mansoni nAChR subunit 0.0043 0.0038 0.0038
Entamoeba histolytica tubulin family protein 0.0027 0.0016 0.0371
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0057 0.0058 0.0684
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0085 0.0085
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0153 0.0153
Brugia malayi hypothetical protein 0.0019 0.0004 0.0004
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Schistosoma mansoni nAChR subunit 0.002 0.0005 0.0005
Onchocerca volvulus Neuropeptide F receptor homolog 0.0081 0.0092 0.0603
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0127 0.1897
Echinococcus multilocularis dro:myosuppressin receptor 0.0081 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.0524 0.0712 0.0712
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0081 0.0092 0.0092
Brugia malayi amidase 0.0537 0.0731 0.0731
Entamoeba histolytica Flap nuclease, putative 0.003 0.0019 0.0496
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0003 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0212
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0043 0.0038 0.0038
Echinococcus multilocularis 0.0019 0.0004 0.0004
Brugia malayi Tubulin beta-1 chain 0.0027 0.0016 0.0016
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0041 0.0041
Schistosoma mansoni biogenic amine (5HT) receptor 0.0081 0.0092 0.0092
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0003 0.0003
Loa Loa (eye worm) PHD-finger family protein 0.003 0.002 0.0016
Brugia malayi Cytochrome P450 family protein 0.0029 0.0018 0.0018
Schistosoma mansoni cellular tumor antigen P53 0.0108 0.0129 0.0129
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0038 0.0038
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.0011 0.0011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0092 0.0092
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0043 0.0038 0.0038
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0081 0.0092 0.0092
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0107 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.0034
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0049 0.0728
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0007 0.0099
Mycobacterium tuberculosis Possible lysophospholipase 0.0077 0.0085 0.1281
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0143 0.2146
Echinococcus multilocularis serotonin receptor 0.0081 0.0092 0.0092
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0077 0.0085 0.1012
Echinococcus granulosus ankyrin repeat protein 0.0155 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0077 0.0085 0.0082
Echinococcus multilocularis protein patched 0.0048 0.0045 0.0045
Leishmania major DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0081 0.0092 0.0092
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0009 0.0009
Loa Loa (eye worm) ACC-1 protein 0.0043 0.0038 0.0034
Echinococcus granulosus fatty acid amide hydrolase 1 0.0537 0.0731 0.0731
Brugia malayi Cytochrome P450 family protein 0.0029 0.0018 0.0018
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0113 0.0136 0.0136
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0004 0.0067
Echinococcus multilocularis cpg binding protein 0.0035 0.0026 0.0026
Leishmania major hypothetical protein, conserved 0.0065 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0052 0.005 0.0046
Brugia malayi Cation transporter family protein 0.0043 0.0038 0.0038
Trypanosoma brucei fructose-1,6-bisphosphatase 0.714 1 1
Toxoplasma gondii fructose-bisphospatase I 0.2655 0.3705 0.3705
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0195 0.0251 0.2974
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0058 0.0865
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0057 0.0058 0.2159
Schistosoma mansoni hypothetical protein 0.0046 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Plasmodium falciparum lysophospholipase, putative 0.0077 0.0085 0.4696
Loa Loa (eye worm) hypothetical protein 0.0537 0.0731 0.0728
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0081 0.0092 0.0092
Brugia malayi putative neuropeptide receptor NPR1 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0086 0.0086
Onchocerca volvulus 0.0081 0.0092 0.0603
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0057 0.0058 0.0058
Echinococcus granulosus 7tm_1 domain containing protein 0.0081 0.0092 0.0092
Toxoplasma gondii hypothetical protein 0.0103 0.0122 0.0122
Mycobacterium ulcerans acyl-CoA synthetase 0.0195 0.0251 0.2974
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0081 0.0092 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0009 0.0009
Brugia malayi excitatory GABA receptor EXP-1A 0.0043 0.0038 0.0038
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0057 0.0058 0.0058
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0143 0.2146
Brugia malayi PHD-finger family protein 0.0032 0.0022 0.0022
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.0004 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0086 0.0086
Schistosoma mansoni lipoxygenase 0.0191 0.0245 0.0245
Giardia lamblia Kinesin-5 0.0122 0.0149 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0034 0.0034
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.003 0.0358
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.0011 0.0166
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0085 0.101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0009 0.0005
Leishmania major acetyl-CoA synthetase, putative 0.0057 0.0058 0.0058
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0086 0.0086
Leishmania major hypothetical protein, conserved 0.003 0.0019 0.0019
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0065 0.0068 0.2587
Schistosoma mansoni hypothetical protein 0.0444 0.06 0.06
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0038 0.0038
Echinococcus granulosus neuropeptide receptor 0.0081 0.0092 0.0092
Echinococcus granulosus tar DNA binding protein 0.0125 0.0153 0.0153
Schistosoma mansoni transcription factor LCR-F1 0.0115 0.0139 0.0139
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0057 0.0058 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0086 0.1023
Echinococcus granulosus sex peptide receptor 0.0081 0.0092 0.0092
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.0004 0.0053
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0006
Schistosoma mansoni neuropeptide receptor 0.0081 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0004
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.004 0.2192
Echinococcus multilocularis sex peptide receptor 0.0081 0.0092 0.0092
Echinococcus granulosus Niemann Pick C1 protein 0.016 0.0203 0.0203
Echinococcus granulosus tubulin beta 4A class IVa 0.0027 0.0016 0.0016
Trichomonas vaginalis maltase-glucoamylase, putative 0.0078 0.0086 0.1023
Brugia malayi Glycosyl hydrolases family 31 protein 0.035 0.0469 0.0469
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0818 0.1126 0.1126
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.003 0.351
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0007 0.0007
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0038 0.0038
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0029 0.0018 0.0018
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0191 0.0245 0.0245
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0041 0.0041
Onchocerca volvulus 0.0113 0.0136 0.0912
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0113 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Loa Loa (eye worm) beta-tubulin 0.0027 0.0016 0.0012
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.714 1 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0002 0.0002
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.0005 0.0005
Leishmania major 0.714 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0009 0.0009
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.0005 0.0002
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0034 0.0034
Loa Loa (eye worm) MH2 domain-containing protein 0.014 0.0173 0.017
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0037 0.2042
Echinococcus granulosus glycine receptor subunit alpha 1 0.0043 0.0038 0.0038
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trichomonas vaginalis sucrase-isomaltase, putative 0.0078 0.0086 0.1023
Brugia malayi AMP-binding enzyme family protein 0.0195 0.0251 0.0251
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0004 0.0067
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0113 0.0136 0.0136
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0038 0.0038
Onchocerca volvulus 0.0081 0.0092 0.0603
Toxoplasma gondii propionate-CoA ligase 0.0057 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0022 0.0008 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0085 0.101
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0143 0.5622
Echinococcus granulosus g-protein coupled receptor 0.0081 0.0092 0.0092
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0085 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0085 0.1012
Leishmania major glycosyl hydrolase-like protein 0.0029 0.0018 0.0018
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0081 0.0092 0.0092
Giardia lamblia TCP-1 chaperonin subunit beta 0.0024 0.0011 0.0718
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0005 0.0005
Brugia malayi G-protein coupled receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0115 0.0139 0.0139
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0195 0.0251 0.3765
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0065 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0108 0.0129 0.0126
Schistosoma mansoni kinesin eg-5 0.0122 0.0149 0.0149
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0047 0.0698
Echinococcus granulosus g protein coupled receptor 0.0081 0.0092 0.0092
Echinococcus multilocularis neuropeptide s receptor 0.0081 0.0092 0.0092
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Schistosoma mansoni thyroid hormone receptor 0.0164 0.0208 0.0208
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0114 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0146 0.0182 0.0179
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Onchocerca volvulus 0.0057 0.0058 0.0366
Plasmodium falciparum lysophospholipase, putative 0.0077 0.0085 0.4696
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Brugia malayi Dopamine receptor protein 2 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0059 0.006 0.0057
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0005
Schistosoma mansoni biogenic amine receptor 0.0081 0.0092 0.0092
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.003 0.003
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.0004 0.0053
Schistosoma mansoni nAChR subunit 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0113 0.0136 0.0133
Echinococcus granulosus glycine receptor subunit alpha 1 0.0043 0.0038 0.0038
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0077 0.0085 0.3283
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0057 0.0058 0.0865
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Toxoplasma gondii beta-1 tubulin, putative 0.0027 0.0016 0.0016
Loa Loa (eye worm) hydrolase 0.1041 0.1439 0.1436
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0003
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0043 0.0038 0.0038
Mycobacterium tuberculosis Probable reductase 0.0106 0.0127 0.1897
Brugia malayi Phospholipase A2 family protein 0.0091 0.0105 0.0105
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0049 0.0049
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0037 0.0037
Leishmania major hypothetical protein, conserved 0.0077 0.0085 0.0085
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0085 0.1279
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0011 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0138 0.0171 0.256
Giardia lamblia Beta tubulin 0.0027 0.0016 0.1055
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0037 0.2042
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus granulosus peptide allatostatin:somatostatin 0.0081 0.0092 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0009 0.0009
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.035 0.0469 0.0465
Loa Loa (eye worm) tubulin beta chain 0.0027 0.0016 0.0012
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.002 0.0005 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Brugia malayi TAR-binding protein 0.0125 0.0153 0.0153
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0038 0.0038
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.003 0.2029
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0009 0.0009
Trypanosoma brucei glycosyl hydrolase-like protein 0.0029 0.0018 0.0018
Plasmodium falciparum phd finger protein, putative 0.003 0.002 0.1077
Trichomonas vaginalis tubulin alpha chain, putative 0.0027 0.0016 0.0186
Brugia malayi Bromodomain containing protein 0.0044 0.004 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0077 0.0085 0.1012
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.001 0.001
Brugia malayi GnHR receptor homolog 0.0081 0.0092 0.0092
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0092 0.0092
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.0011 0.0587
Onchocerca volvulus 0.0081 0.0092 0.0603
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0085 0.1012
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.0004 0.0053
Brugia malayi hypothetical protein 0.0526 0.0716 0.0716
Schistosoma mansoni fatty-acid amide hydrolase 0.0065 0.0068 0.0068
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0212
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0009 0.0009
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0043 0.0043
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0195 0.0251 0.2974
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0009 0.0009
Echinococcus granulosus beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis expressed conserved protein 0.0105 0.0125 0.0125
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0034 0.0034
Schistosoma mansoni biogenic amine receptor 0.0081 0.0092 0.0092
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.003 0.0358
Plasmodium falciparum esterase, putative 0.0077 0.0085 0.4696
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0195 0.0251 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Schistosoma mansoni opsin-like receptor 0.0081 0.0092 0.0092
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus multilocularis zinc finger protein 0.0026 0.0014 0.0014
Brugia malayi Cytochrome P450 family protein 0.0041 0.0035 0.0035
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0146 0.0182 1
Loa Loa (eye worm) hypothetical protein 0.0146 0.0182 0.0179
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0069 0.0069
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0133 0.0164 0.0161
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0014
Mycobacterium ulcerans lipase LipD 0.0077 0.0085 0.101
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0005 0.0005
Onchocerca volvulus 0.0023 0.001 0.0033
Trichomonas vaginalis tubulin epsilon chain, putative 0.0027 0.0016 0.0186
Loa Loa (eye worm) hypothetical protein 0.0146 0.0182 0.0179
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0016 0.0186
Schistosoma mansoni ap endonuclease 0.0038 0.003 0.003
Plasmodium vivax acyl-CoA synthetase, putative 0.0146 0.0182 1
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0142 0.0176 0.0176
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0037 0.0037
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0043 0.0038 0.0034
Brugia malayi putative neuropeptide receptor 0.0081 0.0092 0.0092
Echinococcus granulosus fatty acid amide hydrolase 1 0.0065 0.0068 0.0068
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0057 0.0058 0.0058
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0041 0.0041
Echinococcus multilocularis kinesin family 1 0.094 0.1297 0.1297
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0127 0.1897
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.0004 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0009 0.0009
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0077 0.0085 0.1012
Brugia malayi G-protein coupled receptor 0.0081 0.0092 0.0092
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0007 0.0078
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0303 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0018 0.0212
Schistosoma mansoni neuropeptide F-like receptor 0.0081 0.0092 0.0092
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0015 0.0812
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0009 0.0009
Loa Loa (eye worm) acetylcholine receptor protein 0.002 0.0005 0.0002
Trypanosoma brucei beta tubulin 0.0027 0.0016 0.0016
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.003 0.003
Echinococcus multilocularis neuropeptide FF receptor 2 0.0081 0.0092 0.0092
Echinococcus granulosus neuropeptides capa receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0091 0.0105 0.0101
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0138 0.0171 0.256
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus granulosus G protein coupled receptor 139 0.0081 0.0092 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.003 0.0027
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0081 0.0092 0.0092
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0009 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0058 0.0684
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0009 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0138 0.0171 0.256
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0009 0.0009
Schistosoma mansoni polycystin 1-related 0.0043 0.0037 0.0037
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0057 0.0058 0.0058
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0009 0.0009
Echinococcus granulosus Niemann Pick C1 protein 0.0112 0.0135 0.0135
Echinococcus multilocularis allatostatin A receptor 0.0081 0.0092 0.0092
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0092 0.0092
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0085 0.1279
Echinococcus granulosus tumor protein p63 0.0741 0.1017 0.1017
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0065 0.0068 0.7939
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0153 0.015
Echinococcus multilocularis transient receptor potential cation channel 0.016 0.0201 0.0201
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Echinococcus multilocularis orexin receptor type 2 0.0081 0.0092 0.0092
Echinococcus multilocularis neuropeptides capa receptor 0.0081 0.0092 0.0092
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0005 0.0005
Brugia malayi cytochrome P450 0.0019 0.0004 0.0004
Onchocerca volvulus 0.0043 0.0037 0.0223
Echinococcus multilocularis nAChR subunit 0.0043 0.0038 0.0038
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.0004 0.0053
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0065 0.0068 0.0068
Echinococcus multilocularis flap endonuclease 1 0.003 0.0019 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0057 0.0058 0.0684
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0004 0.0067
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0065 0.0061
Echinococcus granulosus glycine receptor subunit alpha 1 0.0043 0.0038 0.0038
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0081 0.0092 0.0092
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.0011 0.0587
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.0004 0.0053
Leishmania major 4-coumarate:coa ligase-like protein 0.0195 0.0251 0.0251
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0155 0.0194 0.0194
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0034 0.0034
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.003 0.1659
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.1041 0.1439 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0018 0.0212
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0007 0.0078
Toxoplasma gondii exonuclease III APE 0.0038 0.003 0.003
Schistosoma mansoni rab6-interacting 0.0043 0.0037 0.0037
Echinococcus granulosus hypothetical protein 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0065 0.0068 0.1024
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0057 0.0058 0.0865
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0035 0.0032
Mycobacterium ulcerans lysophospholipase 0.0077 0.0085 0.1012
Leishmania major 4-coumarate:coa ligase-like protein 0.0195 0.0251 0.0251
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0007 0.0007
Brugia malayi Thioredoxin reductase 0.0047 0.0043 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0034 0.0034
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.009 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0146 0.0182 0.0179
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0058 0.0865
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0005
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0085 0.1279
Schistosoma mansoni histamine h1 receptor 0.0081 0.0092 0.0092
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0009 0.0009
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0019 0.1031
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0048 0.0045 0.0042
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0043 0.0038 0.0038
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0034 0.0034
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.002 0.002
Echinococcus multilocularis beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0034 0.0034
Mycobacterium ulcerans acetyl-CoA synthetase 0.0057 0.0058 0.0684
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0038 0.0038
Giardia lamblia DINP protein human, muc B family 0.0021 0.0007 0.0445
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0009 0.0005
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0009 0.0005
Loa Loa (eye worm) beta-lactamase 0.0077 0.0085 0.0082
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0168 0.0213 0.0213
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.714 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Echinococcus multilocularis lysosomal alpha glucosidase 0.035 0.0469 0.0469
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0034 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0004 0.0067
Echinococcus multilocularis neuropeptide receptor 0.0081 0.0092 0.0092
Brugia malayi AKH receptor 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0004 0.0067
Leishmania major acetyl-CoA synthetase, putative 0.0057 0.0058 0.0058
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0019 0.1031
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0049 0.0581
Brugia malayi neuropeptide F receptor 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0057 0.0058 0.0865
Onchocerca volvulus 0.0043 0.0038 0.0227
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0153 0.0153
Schistosoma mansoni acetylcholine receptor-related 0.002 0.0005 0.0005
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.003 0.003
Trichomonas vaginalis glutaminase, putative 0.0618 0.0844 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0006
Onchocerca volvulus 0.0057 0.0058 0.0366
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0058 0.0684
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0049 0.2697
Brugia malayi beta-lactamase family protein 0.0077 0.0085 0.0085
Mycobacterium ulcerans acyl-CoA synthetase 0.0195 0.0251 0.2974
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Brugia malayi Doublecortin family protein 0.0043 0.0037 0.0037
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.0011 0.0126
Brugia malayi Tachykinin-like peptides receptor 99D 0.0081 0.0092 0.0092
Brugia malayi Melatonin receptor type 1A 0.0081 0.0092 0.0092
Brugia malayi Serotonin receptor 0.0081 0.0092 0.0092
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0081 0.0092 0.0603
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0007 0.0007
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0057 0.0058 0.0865
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0057 0.0058 0.0054
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0085 0.101
Brugia malayi PHD-finger family protein 0.003 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0081 0.0092 0.0092
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0009 0.0009
Onchocerca volvulus 0.0022 0.0009 0.0024
Brugia malayi Amidase family protein 0.0065 0.0068 0.0068
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0058 0.0058
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0057 0.0058 0.2159
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis microtubule associated protein 2 0.1428 0.1982 0.1982
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Brugia malayi beta-tubulin, identical 0.0027 0.0016 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0081 0.0092 0.0092
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0009 0.0009
Mycobacterium ulcerans hypothetical protein 0.0077 0.0085 0.1012
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.064 0.0875 0.0875
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0005
Schistosoma mansoni opsin-like receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0113 0.0136 0.0133
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0003 0.0003
Brugia malayi ORL1-like opioid receptor 0.0081 0.0092 0.0092
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0019 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0007 0.0007
Schistosoma mansoni neuropeptide receptor 0.0081 0.0092 0.0092
Entamoeba histolytica acyl-coA synthetase, putative 0.0195 0.0251 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.0005 0.0005
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0086 0.4727
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0086 0.4727
Plasmodium vivax glutathione reductase, putative 0.0047 0.0043 0.2349
Echinococcus granulosus glycine receptor subunit beta 0.0043 0.0038 0.0038
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0081 0.0092 0.0092
Toxoplasma gondii beta tubulin 0.0027 0.0016 0.0016
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0009 0.0024
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0004 0.0067
Mycobacterium tuberculosis Conserved protein 0.0077 0.0085 0.1279
Brugia malayi RE15519p 0.0081 0.0092 0.0092
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.003 0.002 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0041 0.0041
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0023 0.001 0.001
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0043 0.0043
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0086 1
Trypanosoma brucei monoglyceride lipase, putative 0.0077 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0046 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0078 0.0086 0.326
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0004 0.0067
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0086 0.4727
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0057 0.0058 0.0058
Echinococcus granulosus fructose 16 bisphosphatase 1 0.714 1 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0049 0.1788
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0086 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Brugia malayi neuropeptide F receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0133 0.0164 0.0161
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0092 0.0092
Brugia malayi CHE-14 protein 0.0048 0.0045 0.0045
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0153 0.0153
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0037 0.0034
Loa Loa (eye worm) kinesin-like protein KLP2 0.0122 0.0149 0.0145
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0002 0.0002
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0195 0.0251 0.0248
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0153 0.0153
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0036 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0004 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0009 0.0005
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0043 0.2349
Loa Loa (eye worm) hypothetical protein 0.0074 0.0082 0.0078
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0009 0.0009
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0057 0.0058 0.0865
Trichomonas vaginalis tubulin epsilon chain, putative 0.0027 0.0016 0.0186
Echinococcus granulosus tubulin beta 1 chain 0.0027 0.0016 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0195 0.0251 0.2974
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0077 0.0085 0.1012
Echinococcus granulosus survival motor neuron protein 1 0.0526 0.0716 0.0716
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0034 0.0034
Echinococcus multilocularis tubulin subunit beta 0.0027 0.0016 0.0016
Trypanosoma brucei beta tubulin 0.0027 0.0016 0.0016
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0085 0.3277
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0086 0.0086
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0007 0.0078
Onchocerca volvulus 0.0081 0.0092 0.0603
Schistosoma mansoni opsin-like receptor 0.0081 0.0092 0.0092
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0092 0.0092
Mycobacterium ulcerans hypothetical protein 0.0337 0.045 0.5334
Echinococcus granulosus dna polymerase eta 0.0021 0.0007 0.0007
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0303 0.0402 0.0402
Plasmodium falciparum tubulin beta chain 0.0027 0.0016 0.0862
Echinococcus multilocularis neutral alpha glucosidase AB 0.0078 0.0086 0.0086
Echinococcus granulosus neuropeptide receptor A26 0.0081 0.0092 0.0092
Echinococcus multilocularis glycine receptor subunit beta 0.0043 0.0038 0.0038
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0043 0.0038 0.0038
Brugia malayi Cation transporter family protein 0.0113 0.0136 0.0136
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0195 0.0251 0.3765
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0009 0.0009
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0065 0.0068 0.1024
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0004 0.0067
Brugia malayi beta-lactamase family protein 0.0077 0.0085 0.0085
Echinococcus granulosus lysosomal alpha glucosidase 0.035 0.0469 0.0469
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.001 0.001
Echinococcus multilocularis neuropeptide Y receptor 0.0081 0.0092 0.0092
Brugia malayi hypothetical protein 0.0133 0.0164 0.0164
Plasmodium falciparum glutathione reductase 0.0047 0.0043 0.2349
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0004 0.0067
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0004 0.0067
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0065 0.0068 0.0809
Brugia malayi glutathione reductase 0.0047 0.0043 0.0043
Brugia malayi G protein-coupled receptor F59B2.13 0.0081 0.0092 0.0092
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0043 0.0038 0.0038
Onchocerca volvulus 0.0113 0.0136 0.0912
Brugia malayi Amidase family protein 0.0065 0.0068 0.0068
Trichomonas vaginalis antibiotic synthetase, putative 0.0057 0.0058 0.0684
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0002 0.0002
Mycobacterium ulcerans hypothetical protein 0.0077 0.0085 0.101
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0303 0.0402 0.0402
Brugia malayi nuclear receptor NHR-88 0.0022 0.0009 0.0009
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0065 0.0068 0.0068
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.003 0.0964
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0085 0.0085
Schistosoma mansoni zinc finger protein 0.0026 0.0014 0.0014
Echinococcus granulosus neuropeptide Y receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0077 0.0085 0.0082
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0009 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0018 0.0015
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0153 0.0153
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0009 0.0005
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0004 0.0004
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0013 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0153 0.0153
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0004 0.0067
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.002 0.0005 0.0002
Trypanosoma brucei beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Loa Loa (eye worm) oxidoreductase 0.0057 0.0058 0.0054
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0113 0.0136 0.0136
Loa Loa (eye worm) BEN-1 protein 0.0027 0.0016 0.0012
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0019 0.0019
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.0004 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Loa Loa (eye worm) neuropeptide F receptor 0.0081 0.0092 0.0088
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Trichomonas vaginalis chaperonin, putative 0.0024 0.0011 0.0126
Schistosoma mansoni microtubule-associated protein tau 0.1428 0.1982 0.1982
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0045 0.0045
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0007 0.0007
Plasmodium falciparum flap endonuclease 1 0.003 0.0019 0.1031
Echinococcus multilocularis nAChR subunit 0.0023 0.001 0.001
Trichomonas vaginalis tubulin gamma chain, putative 0.0027 0.0016 0.0186
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0081 0.0092 0.0092
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0081 0.0092 0.0088
Brugia malayi follicle stimulating hormone receptor 0.0312 0.0416 0.0416
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0019 0.1261
Schistosoma mansoni loxhd1 0.0043 0.0037 0.0037
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0038 0.0038
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0009 0.0009
Schistosoma mansoni biogenic amine (5HT) receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0043 0.0038 0.0034
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.0004 0.0053
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0057 0.0058 0.0865
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0058 0.0684
Schistosoma mansoni amine GPCR 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0085 0.1279
Echinococcus granulosus serotonin receptor 0.0081 0.0092 0.0092
Echinococcus granulosus tm gpcr rhodopsin 0.0081 0.0092 0.0092
Brugia malayi CXXC zinc finger family protein 0.0031 0.0021 0.0021
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0524 0.0712 0.0712
Onchocerca volvulus Alhambra homolog 0.003 0.002 0.01
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0057 0.0058 0.3173
Toxoplasma gondii thioredoxin reductase 0.0047 0.0043 0.0043
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0009 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0085 0.4688
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0043 0.0038 0.0038
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0043 0.0038 0.0038
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0057 0.0058 0.0058
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0029 0.0018 0.0219
Brugia malayi Probable ClpP-like protease 0.0077 0.0086 0.0086
Mycobacterium ulcerans beta-lactamase 0.0077 0.0085 0.101
Echinococcus multilocularis serotonin receptor 0.0081 0.0092 0.0092
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0086 0.3306
Loa Loa (eye worm) RNA binding protein 0.0125 0.0153 0.015
Echinococcus granulosus expressed conserved protein 0.0105 0.0125 0.0125
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.2655 0.3705 0.3705
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0065 0.0068 0.1024
Onchocerca volvulus 0.0081 0.0092 0.0603
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0007 0.0007
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0015 0.0812
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0057 0.0058 0.0058
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0049 0.0049
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0081 0.0092 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.003 0.003
Schistosoma mansoni nAChR subunit 0.0043 0.0038 0.0038
Echinococcus granulosus cpg binding protein 0.0035 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0004 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0019 0.1031
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0034 0.0034
Brugia malayi larval opioid receptor 0.0081 0.0092 0.0092
Schistosoma mansoni ap endonuclease 0.0038 0.003 0.003
Giardia lamblia Beta tubulin 0.0027 0.0016 0.1055
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Mycobacterium ulcerans amidase 0.0065 0.0068 0.0809
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0004 0.0067
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.0004 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0018 0.0212
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.0116 0.0116
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0081 0.0092 0.0092
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0057 0.0058 0.0684
Brugia malayi Glycosyl hydrolases family 31 protein 0.0078 0.0086 0.0086
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0086 0.1023
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0009 0.0024
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0058 0.0058
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0043 0.0043
Echinococcus granulosus alpha 1A adrenergic receptor 0.0081 0.0092 0.0092
Schistosoma mansoni amidase 0.0537 0.0731 0.0731
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0009 0.0009
Brugia malayi Dopamine receptor protein 1 0.0081 0.0092 0.0092
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.0004 0.0053
Schistosoma mansoni nAChR subunit 0.0043 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0006
Echinococcus granulosus neuropeptide Y receptor 0.0081 0.0092 0.0092
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0136
Loa Loa (eye worm) neuropeptide F receptor 0.0081 0.0092 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0004 0.0067
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0078 0.0086 0.1023
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis peregrin 0.0037 0.0029 0.0029
Echinococcus granulosus fmrfamide receptor 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0065 0.0068 0.1024
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0036 0.0036
Loa Loa (eye worm) glutaminase 2 0.0618 0.0844 0.0841
Onchocerca volvulus 0.0081 0.0092 0.0603
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0043 0.0038 0.0038
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0007 0.0007
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0113 0.0136 0.0133
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0153 0.0153
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0007 0.0007
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0041 0.0037
Schistosoma mansoni survival motor neuron protein 0.0107 0.0128 0.0128
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0113 0.0136 0.0136
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0057 0.0058 0.0058
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0077 0.0085 0.3223
Onchocerca volvulus 0.0081 0.0092 0.0603
Brugia malayi Flap endonuclease-1 0.003 0.0019 0.0019
Leishmania major cytochrome p450-like protein 0.0019 0.0004 0.0004
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0078 0.0086 0.326
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.001 0.001
Onchocerca volvulus 0.0077 0.0085 0.0558
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0153 0.015
Loa Loa (eye worm) hypothetical protein 0.0195 0.0251 0.0248
Echinococcus granulosus transient receptor potential cation channel 0.0159 0.0201 0.0201
Onchocerca volvulus 0.0108 0.0129 0.0867
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0081 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.0046 0.0043 0.0043
Schistosoma mansoni nAChR subunit 0.0043 0.0038 0.0038
Schistosoma mansoni alpha-1 adrenergic receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0047 0.0043 0.004
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0037 0.0037
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0057 0.0058 0.2159
Loa Loa (eye worm) hypothetical protein 0.0195 0.0251 0.0248
Echinococcus multilocularis geminin 0.0524 0.0712 0.0712
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0019 0.0222
Brugia malayi hypothetical protein 0.0043 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0142 0.0176 0.0176
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.002 0.0005 0.0005
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0023 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0037 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0057 0.0058 0.0684
Loa Loa (eye worm) hypothetical protein 0.0051 0.0048 0.0045
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0057 0.0058 0.0684
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0034 0.003
Echinococcus granulosus nAChR subunit 0.0023 0.001 0.001
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0019 0.1031
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0034 0.0034
Onchocerca volvulus 0.0081 0.0092 0.0603
Trypanosoma brucei monoglyceride lipase, putative 0.0077 0.0085 0.0085
Echinococcus multilocularis neuropeptides capa receptor 0.0081 0.0092 0.0092
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0009 0.0009
Schistosoma mansoni jumonji domain containing protein 0.0078 0.0087 0.0087
Onchocerca volvulus 0.0081 0.0092 0.0603
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Echinococcus granulosus g protein coupled receptor 0.0081 0.0092 0.0092
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0146 0.0182 0.2155
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Loa Loa (eye worm) glutaminase 0.0618 0.0844 0.0841
Echinococcus multilocularis dna polymerase eta 0.0021 0.0007 0.0007
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0081 0.0092 0.0092
Echinococcus multilocularis tubulin beta 1 chain 0.0027 0.0016 0.0016
Brugia malayi ecdysteroid receptor 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Echinococcus granulosus tachykinin peptides receptor 99D 0.0081 0.0092 0.0092
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.0004 0.0053
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.0004 0.0053
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0078 0.0086 0.0086
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0009 0.0009
Mycobacterium ulcerans amidase 0.0065 0.0068 0.0809
Schistosoma mansoni lipoxygenase 0.0114 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0057 0.0058 0.0054
Schistosoma mansoni alpha glucosidase 0.0078 0.0086 0.0086
Leishmania major trypanothione reductase 0.0047 0.0043 0.0043
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0065 0.0068 0.0068
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0049 0.0728
Echinococcus granulosus dna polymerase kappa 0.0021 0.0007 0.0007
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0085 0.0085
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0077 0.0085 0.3223
Plasmodium vivax kinesin-5 0.0122 0.0149 0.8178
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0085 0.0082
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0037 0.0037
Echinococcus granulosus tm gpcr rhodopsin 0.0081 0.0092 0.0092
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Echinococcus multilocularis g-protein coupled receptor 0.0081 0.0092 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0004 0.0067
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.002 0.0005 0.0005
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0065 0.0068 0.3753
Echinococcus granulosus orexin receptor type 2 0.0081 0.0092 0.0092
Echinococcus multilocularis g protein coupled receptor 0.0081 0.0092 0.0092
Brugia malayi hypothetical protein 0.0081 0.0092 0.0092
Echinococcus multilocularis G-protein coupled receptor, putative 0.0081 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0057 0.0058 0.0058
Schistosoma mansoni amine GPCR 0.0081 0.0092 0.0092
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0018 0.0018
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0045 0.0045
Onchocerca volvulus 0.0077 0.0085 0.0558
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0037 0.0037
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0029 0.0018 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0081 0.0092 0.0092
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0085 0.0085
Onchocerca volvulus 0.0057 0.0058 0.0366
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0004 0.0067
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0034 0.0408
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0113 0.0136 0.0136
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.003 0.003
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0009 0.0009
Echinococcus multilocularis beta tubulin 0.0027 0.0016 0.0016
Brugia malayi hypothetical protein 0.0115 0.0139 0.0139
Trypanosoma cruzi amidase, putative 0.0065 0.0068 0.0068
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0491 0.0667 1
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0057 0.0058 0.0058
Leishmania major beta tubulin 0.0027 0.0016 0.0016
Echinococcus multilocularis G protein coupled receptor 139 0.0081 0.0092 0.0092
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0049 0.0049
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0081 0.0092 0.0092
Brugia malayi steroid hormone receptor 0.0022 0.0009 0.0009
Echinococcus granulosus geminin 0.0524 0.0712 0.0712
Loa Loa (eye worm) acetyltransferase 0.0168 0.0213 0.0209
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0081 0.0092 0.0088
Loa Loa (eye worm) hypothetical protein 0.0077 0.0085 0.0082
Schistosoma mansoni growth hormone secretagogue receptor 0.0081 0.0092 0.0092
Onchocerca volvulus Huntingtin homolog 0.0133 0.0164 0.1107
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0009 0.0009
Plasmodium falciparum kinesin-5 0.0122 0.0149 0.8178
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0007 0.0007
Trypanosoma brucei DNA polymerase beta thumb, putative 0.009 0.0104 0.0104
Echinococcus multilocularis Tubulin beta 2C chain 0.0027 0.0016 0.0016
Entamoeba histolytica kinesin, putative 0.0122 0.0149 0.5814
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.0004 0.0053
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.0004 0.0053
Echinococcus granulosus Tubulin beta 2C chain 0.0027 0.0016 0.0016
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0019 0.0019
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.0004 0.0053
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0003 0.0003
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0081 0.0092 0.0092
Onchocerca volvulus 0.0081 0.0092 0.0603
Onchocerca volvulus 0.0195 0.0251 0.1716
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0002
Brugia malayi RNA binding protein 0.0125 0.0153 0.0153
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0138 0.0171 0.256
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0009 0.0009
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0057 0.0058 0.0054
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0195 0.0251 0.2974
Schistosoma mansoni hypothetical protein 0.0115 0.0139 0.0139
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.2655 0.3705 0.3705
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0011 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0195 0.0251 0.0251
Brugia malayi Cation transporter family protein 0.0043 0.0038 0.0038
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Brugia malayi hypothetical protein 0.0043 0.0037 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0086 0.0086
Trypanosoma brucei beta tubulin 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0081 0.0092 0.0088
Entamoeba histolytica hypothetical protein 0.0115 0.0139 0.5398
Schistosoma mansoni bromodomain containing protein 0.0072 0.0079 0.0079
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0009 0.0009
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0034 0.2314
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2607 0.3637 0.3637
Toxoplasma gondii kinesin motor domain-containing protein 0.0122 0.0149 0.0149
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0057 0.0058 0.0865
Echinococcus multilocularis somatostatin receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0045 0.0042
Brugia malayi glutaminase DH11.1 0.0618 0.0844 0.0844
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0115 0.0139 0.0139
Echinococcus granulosus fatty acid amide hydrolase 1 0.0537 0.0731 0.0731
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.2655 0.3705 0.3705
Schistosoma mansoni patched 1 0.0048 0.0045 0.0045
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.003 0.0453
Loa Loa (eye worm) hypothetical protein 0.0043 0.0038 0.0034
Echinococcus granulosus g protein coupled receptor 0.0081 0.0092 0.0092
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0043 0.0038 0.0034
Schistosoma mansoni neuropeptide F-like receptor 0.0081 0.0092 0.0092
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0007 0.0007
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0021 0.0018
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0081 0.0092 0.0092
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0081 0.0092 0.0092
Schistosoma mansoni tubulin subunit beta 0.0027 0.0016 0.0016
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0009 0.0009
Echinococcus multilocularis dnaJ subfamily B 0.0444 0.06 0.06
Schistosoma mansoni thyroid hormone receptor 0.0164 0.0208 0.0208
Loa Loa (eye worm) cytochrome P450 0.0019 0.0004 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0057 0.0058 0.0058
Echinococcus multilocularis fmrfamide receptor 0.0081 0.0092 0.0092
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0086 0.1019
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0081 0.0092 0.0092
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0007 0.0007
Brugia malayi MH2 domain containing protein 0.014 0.0173 0.0173
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0081 0.0092 0.0092
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0065 0.0068 0.2587
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.0006
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.0116 0.0116
Echinococcus granulosus peregrin 0.0037 0.0029 0.0029
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0009 0.0009
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0019 0.0019
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.714 1 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0007 0.0099
Loa Loa (eye worm) hypothetical protein 0.0077 0.0085 0.0082

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 1.7 nM Agonist activity at human MC4R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay ChEMBL. 18771254
EC50 (functional) = 50 nM Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay ChEMBL. 18771254
EC50 (functional) = 51 nM Agonist activity at human MC3R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay ChEMBL. 18771254
Emax (functional) = 78 % Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay relative to NDP-MSH ChEMBL. 18771254
Emax (functional) = 92 % Agonist activity at human MC4R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay relative to NDP-MSH ChEMBL. 18771254
Emax (functional) = 93 % Agonist activity at human MC3R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay relative to NDP-MSH ChEMBL. 18771254
Ki (binding) = 6 nM Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells ChEMBL. 18771254
Ki (binding) = 101 nM Displacement of europium-labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cells ChEMBL. 18771254
Ki (binding) = 207 nM Displacement of europium-labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cells ChEMBL. 18771254

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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