Detailed information for compound 957689

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 334.325 | Formula: C19H14N2O4
  • H donors: 0 H acceptors: 4 LogP: 3.62 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1c2c(C)cccn2c2c1C(=O)c1ncccc1C2=O
  • InChi: 1S/C19H14N2O4/c1-3-25-19(24)13-12-16(21-9-5-6-10(2)15(13)21)17(22)11-7-4-8-20-14(11)18(12)23/h4-9H,3H2,1-2H3
  • InChiKey: RPESDIWLFSAZET-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0063 0.0121 0.0364
Mycobacterium tuberculosis Possible penicillin-binding protein 0.117 0.3253 0.3243
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0116 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0014 0.005
Plasmodium vivax prefoldin subunit 6, putative 0.0063 0.0121 0.2381
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Trypanosoma cruzi hypothetical protein, conserved 0.0183 0.0462 0.1419
Leishmania major short chain dehydrogenase/reductase, putative 0.0049 0.0083 0.0244
Toxoplasma gondii hypothetical protein 0.0196 0.0497 0.1539
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0026 0.0067
Leishmania major short chain dehydrogenase, putative 0.0049 0.0083 0.0244
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0331 0.1014
Loa Loa (eye worm) proprotein convertase 2 0.0025 0.0014 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Onchocerca volvulus 0.0189 0.0478 0.1481
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0049 0.0228
Schistosoma mansoni carbonyl reductase 0.0049 0.0083 0.0244
Echinococcus multilocularis geminin 0.017 0.0424 0.1302
Trichomonas vaginalis esterase, putative 0.0183 0.0462 0.232
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.1621 0.8196
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.02 0.0608
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Echinococcus multilocularis caspase 2 0.006 0.0114 0.0339
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Brugia malayi Pre-SET motif family protein 0.0091 0.02 0.062
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0116 0.0102
Echinococcus granulosus importin subunit beta 1 0.0029 0.0026 0.0067
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1162 0.323 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0049 0.0083 0.0398
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0183 0.0462 0.1419
Mycobacterium tuberculosis Conserved protein 0.0183 0.0462 0.0449
Loa Loa (eye worm) beta-lactamase 0.0183 0.0462 0.143
Entamoeba histolytica prolyl oligopeptidase family protein 0.0196 0.0497 0.3049
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Mycobacterium ulcerans beta-lactamase 0.0183 0.0462 0.0449
Onchocerca volvulus 0.0049 0.0083 0.0256
Schistosoma mansoni site-1 peptidase (S08 family) 0.0025 0.0014 0.003
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0517 0.1406 0.4346
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0049 0.0083 0.0244
Leishmania major pteridine reductase 1 0.0049 0.0083 0.0244
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0049 0.0083 0.1595
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Onchocerca volvulus 0.0186 0.047 0.1454
Loa Loa (eye worm) hypothetical protein 0.1162 0.323 1
Schistosoma mansoni inositol monophosphatase 0.0037 0.0049 0.0139
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0049 0.0083 0.0244
Loa Loa (eye worm) prolyl oligopeptidase 0.1041 0.2886 0.8934
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0223 0.0574 0.1768
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.1621 0.8196
Mycobacterium ulcerans dehydrogenase/reductase 0.0049 0.0083 0.0069
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0055 0.0159
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0424 0.2128
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0014 0.005
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0026 0.0079
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0152 0.0459
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0026 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Leishmania major short chain dehydrogenase, putative 0.0049 0.0083 0.0244
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0016 0.005
Leishmania major prefoldin subunit, putative 0.0063 0.0121 0.0364
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0024 0.0404
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0041 0.0114
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Onchocerca volvulus 0.0037 0.0049 0.015
Brugia malayi hypothetical protein 0.006 0.0114 0.0351
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Echinococcus multilocularis carbonyl reductase 1 0.0049 0.0083 0.0244
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0593 0.1621 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Leishmania major subtilisin-like serine peptidase 0.0025 0.0014 0.003
Plasmodium vivax steroid dehydrogenase, putative 0.0049 0.0083 0.1595
Mycobacterium tuberculosis Probable lipase LipD 0.0183 0.0462 0.0449
Leishmania major quinonoid dihydropteridine reductase 0.0049 0.0083 0.0244
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0049 0.0083 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0121 0.0595
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0038
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0116 0.0347
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0049 0.0139
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0083 0.0244
Loa Loa (eye worm) oxidoreductase 0.0049 0.0083 0.0256
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0049 0.0083 0.0244
Brugia malayi prolyl oligopeptidase family protein 0.0196 0.0497 0.1539
Plasmodium falciparum phd finger protein, putative 0.0028 0.0024 0.0404
Entamoeba histolytica hypothetical protein 0.0049 0.0083 0.0486
Mycobacterium ulcerans short-chain dehydrogenase 0.0049 0.0083 0.0069
Toxoplasma gondii carbonyl reductase 1, putative 0.0049 0.0083 0.0256
Echinococcus granulosus hypothetical protein 0.0049 0.0083 0.0244
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0049 0.0083 0.0244
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.008 0.0234
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0049 0.0139
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0083 0.0244
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0049 0.0083 0.0256
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Schistosoma mansoni inositol monophosphatase 0.0037 0.0049 0.0139
Leishmania major quinonoid dihydropteridine reductase 0.0049 0.0083 0.0244
Onchocerca volvulus 0.0037 0.0049 0.015
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Onchocerca volvulus 0.0049 0.0083 0.0256
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0049 0.0138
Leishmania major short chain dehydrogenase/reductase, putative 0.0049 0.0083 0.0244
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0049 0.0083 0.05
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.008 0.0234
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Loa Loa (eye worm) endoprotease bli-4 0.0025 0.0014 0.0043
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0369 0.0987 0.3048
Entamoeba histolytica short chain dehydrogenase family protein 0.0049 0.0083 0.0486
Toxoplasma gondii subtilisin SUB4 0.0025 0.0014 0.0043
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Onchocerca volvulus Sepiapterin reductase homolog 0.0049 0.0083 0.0256
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0719 0.1976 0.6113
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0049 0.0083 0.0244
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0049 0.0083 0.0244
Loa Loa (eye worm) hypothetical protein 0.0055 0.0098 0.0305
Entamoeba histolytica short chain dehydrogenase family protein 0.0049 0.0083 0.0486
Echinococcus granulosus membrane bound transcription factor site 1 0.0025 0.0014 0.003
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Plasmodium vivax importin-beta 2, putative 0.0029 0.0026 0.0437
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.029 0.0763 0.0751
Echinococcus granulosus snurportin 1 0.0308 0.0816 0.2517
Trypanosoma cruzi hypothetical protein, conserved 0.0183 0.0462 0.1419
Brugia malayi Protein kinase domain containing protein 0.0056 0.0103 0.0319
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0049 0.0139
Toxoplasma gondii subtilisin SUB10 0.0025 0.0014 0.0043
Echinococcus granulosus neuroendocrine convertase 2 0.0025 0.0014 0.003
Treponema pallidum fructose-bisphosphate aldolase 0.0593 0.1621 0.5
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Echinococcus granulosus beta LACTamase domain containing family member 0.0183 0.0462 0.1419
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0049 0.0083 0.0256
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0143 0.0432
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.015
Brugia malayi Kringle domain containing protein 0.0056 0.0103 0.0319
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0049 0.0083 0.0244
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0049 0.0083 0.0486
Schistosoma mansoni inhibitor of apoptosis protein 0.0189 0.0478 0.147
Toxoplasma gondii subtilisin SUB8 0.0025 0.0014 0.0043
Loa Loa (eye worm) oxidoreductase 0.0049 0.0083 0.0256
Brugia malayi neuroendocrine convertase 1 precursor 0.0025 0.0014 0.0043
Loa Loa (eye worm) oxidoreductase 0.0049 0.0083 0.0256
Brugia malayi dehydrogenases, short chain protein 2 0.0049 0.0083 0.0256
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Brugia malayi prolyl oligopeptidase family protein 0.1041 0.2886 0.8934
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0049 0.0083 0.0069
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0049 0.0152
Trypanosoma brucei short-chain dehydrogenase, putative 0.0049 0.0083 0.0244
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0049 0.0083 0.0244
Schistosoma mansoni carbonyl reductase 0.0049 0.0083 0.0244
Trichomonas vaginalis set domain proteins, putative 0.0719 0.1977 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Plasmodium falciparum subtilisin-like protease 2 0.0025 0.0014 0.0199
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0189 0.0478 0.147
Loa Loa (eye worm) oxidoreductase 0.0049 0.0083 0.0256
Onchocerca volvulus 0.0049 0.0083 0.0256
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Brugia malayi hypothetical protein 0.0037 0.0049 0.015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0074
Echinococcus multilocularis carbonyl reductase 1 0.0049 0.0083 0.0244
Echinococcus granulosus p2X purinoceptor 4 0.0071 0.0144 0.0435
Echinococcus multilocularis carbonyl reductase 1 0.0049 0.0083 0.0244
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Mycobacterium tuberculosis Probable oxidoreductase 0.0049 0.0083 0.0069
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.008 0.0234
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0196 0.0497 0.3049
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0049 0.0278
Echinococcus multilocularis oxidoreductase 0.0049 0.0083 0.0244
Trypanosoma cruzi prefoldin subunit, putative 0.0063 0.0121 0.0364
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.1621 0.8196
Echinococcus multilocularis prolyl endopeptidase 0.1162 0.323 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0223 0.0574 0.1768
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0049 0.0083 0.0244
Echinococcus granulosus hypothetical protein 0.0049 0.0083 0.0244
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0676 0.3403
Schistosoma mansoni furin-1 (S08 family) 0.0025 0.0014 0.003
Toxoplasma gondii prolyl endopeptidase 0.1162 0.323 1
Echinococcus multilocularis enteropeptidase 0.0037 0.0049 0.0138
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0085 0.0264
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0196 0.0497 0.3049
Leishmania major quinonoid dihydropteridine reductase 0.0049 0.0083 0.0244
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Mycobacterium tuberculosis Possible oxidoreductase 0.0049 0.0083 0.0069
Entamoeba histolytica hypothetical protein 0.0071 0.0143 0.0862
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0676 0.3403
Onchocerca volvulus 0.0037 0.0049 0.015
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0049 0.0083 0.0069
Loa Loa (eye worm) glutaminase 0.0555 0.1513 0.4683
Brugia malayi MH2 domain containing protein 0.0116 0.0273 0.0846
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Loa Loa (eye worm) trypsin family protein 0.0037 0.0049 0.015
Onchocerca volvulus 0.0183 0.0462 0.143
Schistosoma mansoni retinal dehydrogenase 0.0049 0.0083 0.0244
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Echinococcus multilocularis retinol dehydrogenase 11 0.0049 0.0083 0.0244
Echinococcus granulosus peregrin 0.0028 0.0024 0.0062
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0116 0.0347
Schistosoma mansoni hypothetical protein 0.0028 0.0024 0.0062
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0041 0.0126
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0196 0.0497 0.1539
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0049 0.0138
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0206 0.0626
Plasmodium falciparum subtilisin-like protease 1 0.0025 0.0014 0.0199
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0049 0.0083 0.0244
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0049 0.0083 0.0069
Mycobacterium tuberculosis Conserved protein 0.0183 0.0462 0.0449
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0183 0.0462 0.0449
Mycobacterium ulcerans ketoacyl reductase 0.0049 0.0083 0.0069
Mycobacterium tuberculosis Probable oxidoreductase 0.0049 0.0083 0.0069
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0109 0.0338
Trypanosoma brucei prefoldin subunit, putative 0.0063 0.0121 0.0364
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0517 0.1406 0.4346
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0801 0.2208 0.6831
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0103 0.0307
Schistosoma mansoni P2X receptor subunit 0.0071 0.0144 0.0435
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0424 0.2128
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.1041 0.2886 0.8933
Schistosoma mansoni glutaminase 0.0555 0.1513 0.4677
Brugia malayi jmjC domain containing protein 0.0034 0.0041 0.0126
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0676 0.3403
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0025 0.0014 0.003
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0116 0.0102
Loa Loa (eye worm) oxidoreductase 0.0049 0.0083 0.0256
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0517 0.1406 0.4346
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0676 0.3403
Trichomonas vaginalis penicillin-binding protein, putative 0.0183 0.0462 0.232
Toxoplasma gondii subtilisin SUB11 0.0025 0.0014 0.0043
Mycobacterium ulcerans hypothetical protein 0.0037 0.0049 0.0035
Onchocerca volvulus 0.0049 0.0083 0.0256
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.02 0.0608
Echinococcus multilocularis Mastin 0.0037 0.0049 0.0138
Loa Loa (eye worm) hypothetical protein 0.0183 0.0462 0.143
Onchocerca volvulus 0.0049 0.0083 0.0256
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0049 0.0083 0.0244
Toxoplasma gondii subtilisin SUB5 0.0025 0.0014 0.0043
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.03 0.0792 0.2441
Onchocerca volvulus Cell death protein 3 homolog 0.006 0.0114 0.0351
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0049 0.0083 0.0398
Brugia malayi prolyl oligopeptidase family protein 0.0196 0.0497 0.1539
Echinococcus multilocularis tissue type plasminogen activator 0.0056 0.0103 0.0307
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0517 0.1406 0.4346
Brugia malayi mbt repeat family protein 0.0048 0.008 0.0246
Echinococcus granulosus carbonyl reductase 1 0.0049 0.0083 0.0244
Onchocerca volvulus 0.0183 0.0462 0.143
Plasmodium vivax SET domain protein, putative 0.0091 0.02 0.3978
Schistosoma mansoni P2X receptor subunit 0.0071 0.0144 0.0435
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Toxoplasma gondii subtilisin SUB7 0.0025 0.0014 0.0043
Leishmania major dehydrogenase-like protein 0.0049 0.0083 0.0244
Toxoplasma gondii kringle domain-containing protein 0.0056 0.0103 0.0319
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.008 0.0234
Echinococcus multilocularis peregrin 0.0028 0.0024 0.0062
Leishmania major oxidoreductase-like protein 0.0049 0.0083 0.0244
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.1041 0.2886 0.8933
Trypanosoma brucei oligopeptidase b 0.0512 0.1391 0.4299
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0049 0.0083 0.0398
Loa Loa (eye worm) hypothetical protein 0.005 0.0085 0.0264
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0098 0.0293
Loa Loa (eye worm) dehydrogenase 0.0049 0.0083 0.0256
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0206 0.0626
Mycobacterium ulcerans short-chain type oxidoreductase 0.0049 0.0083 0.0069
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.015
Schistosoma mansoni hypothetical protein 0.017 0.0424 0.1302
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0049 0.0083 0.05
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0004 0.0012
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0049 0.0083 0.0244
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0079
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0049 0.0138
Echinococcus granulosus prefoldin subunit 6 0.0063 0.0121 0.0364
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0369 0.0987 0.3048
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0083 0.0486
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0024 0.0062
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0049 0.0083 0.0244
Loa Loa (eye worm) hypothetical protein 0.0267 0.0699 0.2164
Brugia malayi KE2 family protein 0.0063 0.0121 0.0376
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0049 0.0083 0.0256
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.03 0.0792 0.2441
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0043
Schistosoma mansoni P2X receptor subunit 0.0071 0.0144 0.0435
Plasmodium falciparum prefoldin subunit 6, putative 0.0063 0.0121 0.2381
Toxoplasma gondii subtilisin SUB2 0.0025 0.0014 0.0043
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.008 0.0234
Trypanosoma brucei C-8 sterol isomerase, putative 0.0719 0.1976 0.6113
Brugia malayi Trypsin family protein 0.0037 0.0049 0.015
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0049 0.0083 0.0069
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.029 0.0763 0.5442
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.02 0.0608
Schistosoma mansoni importin beta-1 0.0029 0.0026 0.0067
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Leishmania major oligopeptidase b 0.0512 0.1391 0.4299
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0183 0.0462 0.143
Echinococcus granulosus p2X purinoceptor 4 0.0071 0.0144 0.0435
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0331 0.1014
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0038 0.0024
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.004 0.0125
Brugia malayi proprotein convertase 2 0.0025 0.0014 0.0043
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0632 0.1731 0.5357
Echinococcus granulosus WW domain containing oxidoreductase 0.0049 0.0083 0.0244
Brugia malayi beta-lactamase family protein 0.0183 0.0462 0.143
Loa Loa (eye worm) hypothetical protein 0.0189 0.0478 0.1481
Echinococcus multilocularis snurportin 1 0.0308 0.0816 0.2517
Mycobacterium tuberculosis Probable peptidase 0.0512 0.1391 0.1379
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0424 0.2128
Echinococcus granulosus glycoprotein Antigen 5 0.0037 0.0049 0.0138
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0025 0.0014 0.003
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0049 0.0083 0.0244
Schistosoma mansoni hypothetical protein 0.0071 0.0143 0.0432
Onchocerca volvulus 0.0049 0.0083 0.0256
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0049 0.0083 0.0244
Brugia malayi Trypsin family protein 0.0037 0.0049 0.015
Toxoplasma gondii subtilisin SUB1 0.0025 0.0014 0.0043
Loa Loa (eye worm) oxidoreductase 0.0049 0.0083 0.0256
Brugia malayi glutaminase DH11.1 0.0555 0.1513 0.4683
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0049 0.0083 0.0256
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0196 0.0497 0.2499
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0037 0.0049 0.0138
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.1041 0.2886 0.8934
Mycobacterium tuberculosis Probable hydrolase 0.0183 0.0462 0.0449
Mycobacterium ulcerans dehydrogenase 0.0049 0.0083 0.0069
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0049 0.0083 0.0398
Echinococcus granulosus carbonyl reductase 1 0.0049 0.0083 0.0244
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0049 0.0083 0.0244
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Onchocerca volvulus 0.0049 0.0083 0.0256
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.1041 0.2886 0.8933
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0125
Trichomonas vaginalis D-aminoacylase, putative 0.0183 0.0462 0.232
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Brugia malayi Pre-SET motif family protein 0.0632 0.1731 0.5357
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0273 0.0846
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0004 0.0012
Echinococcus granulosus oxidoreductase 0.0049 0.0083 0.0244
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0116 0.0347
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0049 0.0083 0.0069
Mycobacterium ulcerans short chain dehydrogenase 0.3556 1 1
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0049 0.0083 0.0244
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0049 0.0083 0.0244
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0025 0.0014 0.003
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0369 0.0987 0.3048
Echinococcus granulosus Mastin 0.0037 0.0049 0.0138
Trypanosoma cruzi oligopeptidase b 0.0512 0.1391 0.4299
Giardia lamblia Alanyl dipeptidyl peptidase 0.0196 0.0497 0.3049
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0331 0.1014
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Echinococcus multilocularis retinol dehydrogenase 13 0.0049 0.0083 0.0244
Onchocerca volvulus 0.0049 0.0083 0.0256
Brugia malayi jmjC domain containing protein 0.0093 0.0206 0.0638
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0331 0.1014
Echinococcus granulosus enteropeptidase 0.0037 0.0049 0.0138
Trypanosoma brucei oxidoreductase-like protein 0.0049 0.0083 0.0244
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0049 0.0083 0.0398
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0137 0.0331 0.1025
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0024 0.0074
Echinococcus multilocularis conserved hypothetical protein 0.0049 0.0083 0.0244
Onchocerca volvulus 0.0719 0.1977 0.6121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.1621 0.8196
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0004 0.0012
Giardia lamblia Alanyl dipeptidyl peptidase 0.0196 0.0497 0.3049
Plasmodium vivax hypothetical protein, conserved 0.0049 0.0083 0.1595
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0049 0.0083 0.0244
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0116 0.0359
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0049 0.0138
Plasmodium vivax subtilisin-like protease 1 0.0025 0.0014 0.0199
Loa Loa (eye worm) oxidoreductase 0.0049 0.0083 0.0256
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0025 0.0014 0.003
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0049 0.0083 0.0244
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0512 0.1391 0.4299
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0018 0.0056
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.008 0.0246
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.02 0.062
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0083 0.0244
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0049 0.0083 0.0486
Leishmania major quinonoid dihydropteridine reductase 0.0049 0.0083 0.0244
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0189 0.0478 0.1481
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Echinococcus granulosus apoptotic protease activating factor 1 0.006 0.0114 0.0339
Schistosoma mansoni P2X receptor subunit 0.0071 0.0144 0.0435
Leishmania major C-8 sterol isomerase-like protein 0.0719 0.1976 0.6113
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.0816 0.2526
Echinococcus multilocularis Furin 1 0.0025 0.0014 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0191 0.0579
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.045 0.2259
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0049 0.0083 0.0244
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Plasmodium falciparum cysteine repeat modular protein 1 0.0056 0.0103 0.2011
Mycobacterium tuberculosis Probable esterase LipL 0.0183 0.0462 0.0449
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0049 0.0083 0.0486
Mycobacterium ulcerans lipase LipD 0.0183 0.0462 0.0449
Echinococcus granulosus tissue type plasminogen activator 0.0056 0.0103 0.0307
Toxoplasma gondii subtilisin SUB12 0.0045 0.007 0.0216
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0049 0.0083 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.045 0.2259
Loa Loa (eye worm) hypothetical protein 0.0183 0.0462 0.143
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0049 0.0083 0.0244
Brugia malayi hypothetical protein 0.0071 0.0143 0.0444
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0517 0.1406 0.4346
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0719 0.1976 0.6117
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0049 0.0139
Plasmodium vivax hypothetical protein, conserved 0.0183 0.0462 0.9284
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Loa Loa (eye worm) hypothetical protein 0.0183 0.0462 0.143
Onchocerca volvulus Prolyl endopeptidase homolog 0.1162 0.323 1
Entamoeba histolytica hypothetical protein 0.0071 0.0143 0.0862
Schistosoma mansoni site-1 peptidase (S08 family) 0.0025 0.0014 0.003
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0049 0.0083 0.05
Leishmania major hypothetical protein, conserved 0.0049 0.0083 0.0244
Echinococcus multilocularis acylamino acid releasing enzyme 0.0196 0.0497 0.1528
Entamoeba histolytica prolyl oligopeptidase family protein 0.0196 0.0497 0.3049
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0183 0.0462 0.1419
Trypanosoma cruzi short chain dehydrogenase, putative 0.0049 0.0083 0.0244
Trichomonas vaginalis D-aminoacylase, putative 0.0183 0.0462 0.232
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0512 0.1391 0.4299
Echinococcus granulosus carbonyl reductase 1 0.0049 0.0083 0.0244
Leishmania major quinonoid dihydropteridine reductase 0.0049 0.0083 0.0244
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Brugia malayi mbt repeat family protein 0.0048 0.008 0.0246
Brugia malayi Inositol-1 0.0037 0.0049 0.0152
Echinococcus multilocularis membrane bound transcription factor site 1 0.0025 0.0014 0.003
Giardia lamblia PHD finger protein 15 0.0028 0.0024 0.0123
Brugia malayi Trypsin family protein 0.0037 0.0049 0.015
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0049 0.0083 0.0244
Leishmania major short chain dehydrogenase-like protein 0.0049 0.0083 0.0244
Onchocerca volvulus Deterin homolog 0.0189 0.0478 0.1481
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0049 0.0083 0.0398
Loa Loa (eye worm) hypothetical protein 0.0049 0.0081 0.0251
Mycobacterium ulcerans oxidoreductase 0.0049 0.0083 0.0069
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0193 0.0489 0.1504
Schistosoma mansoni hypothetical protein 0.0037 0.0049 0.0138
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0049 0.0083 0.0069
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0083 0.0244
Brugia malayi prolyl oligopeptidase family protein 0.0517 0.1406 0.4353
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0049 0.0083 0.0069
Trypanosoma brucei hypothetical protein, conserved 0.0183 0.0462 0.1419
Onchocerca volvulus 0.0037 0.0049 0.015
Loa Loa (eye worm) oxidoreductase 0.0049 0.0083 0.0256
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0037 0.0049 0.0138
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0049 0.0083 0.0486
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0025 0.0014 0.0043
Brugia malayi Cell death protein 3 precursor 0.006 0.0114 0.0351
Loa Loa (eye worm) hypothetical protein 0.006 0.0114 0.0351
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.1621 0.8196
Onchocerca volvulus Alhambra homolog 0.0028 0.0024 0.0074
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Plasmodium vivax subtilisin-like protease 2, putative 0.0025 0.0014 0.0199
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0016 0.0038
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0025 0.0014 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0196 0.0497 0.1528
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0016 0.0038
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0183 0.0462 0.0449
Echinococcus multilocularis steroid dehydrogenase 0.0049 0.0083 0.0244
Loa Loa (eye worm) hypothetical protein 0.0183 0.0462 0.143
Leishmania major quinonoid dihydropteridine reductase 0.0049 0.0083 0.0244
Mycobacterium tuberculosis Probable dehydrogenase 0.0049 0.0083 0.0069
Echinococcus multilocularis beta LACTamase domain containing family member 0.0183 0.0462 0.1419
Brugia malayi beta-lactamase 0.0183 0.0462 0.143
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Echinococcus granulosus transmembrane protease serine 3 0.0037 0.0049 0.0138
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Brugia malayi endoprotease bli-4 precursor 0.0025 0.0014 0.0043
Entamoeba histolytica prefoldin subunit 6, putative 0.0063 0.0121 0.0726
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0049 0.0083 0.0244
Leishmania major hypothetical protein, conserved 0.0183 0.0462 0.1419
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.0041 0.0114
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0043
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0049 0.0035
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0193 0.0489 0.1504
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0038 0.0175
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Echinococcus granulosus inhibitor of apoptosis protein 0.0189 0.0478 0.147
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0517 0.1406 0.4346
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0049 0.0083 0.0486
Echinococcus granulosus Dipeptidyl peptidase 9 0.0517 0.1406 0.4346
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0024 0.0062
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0049 0.0083 0.0244
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0331 0.1014
Giardia lamblia Reductase, putative 0.0049 0.0083 0.0486
Trichomonas vaginalis D-aminoacylase, putative 0.0183 0.0462 0.232
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.02 0.0608
Schistosoma mansoni hypothetical protein 0.006 0.0114 0.0339
Echinococcus multilocularis carbonyl reductase 1 0.0049 0.0083 0.0244
Toxoplasma gondii subtilisin SUB9 0.0025 0.0014 0.0043
Echinococcus granulosus caspase 2 0.006 0.0114 0.0339
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0196 0.0497 0.1528
Mycobacterium ulcerans short-chain dehydrogenase 0.0049 0.0083 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0091 0.02 0.0608
Brugia malayi dehydrogenases, short chain protein 9 0.0049 0.0083 0.0256
Schistosoma mansoni hypothetical protein 0.0034 0.004 0.0113
Echinococcus multilocularis apoptotic protease activating factor 1 0.006 0.0114 0.0339
Brugia malayi Subtilase family protein 0.0801 0.2208 0.6835
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0056 0.0103 0.2011
Brugia malayi PHD-finger family protein 0.0028 0.0024 0.0074
Mycobacterium tuberculosis Probable oxidoreductase 0.0049 0.0083 0.0069
Leishmania major hypothetical protein, conserved 0.0049 0.0083 0.0244
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0049 0.0083 0.0256
Echinococcus granulosus Furin 1 0.0025 0.0014 0.003
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0026 0.0067
Mycobacterium tuberculosis Probable oxidoreductase 0.0049 0.0083 0.0069
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.008 0.0234
Brugia malayi hypothetical protein 0.0049 0.0083 0.0256
Plasmodium falciparum importin beta, putative 0.0029 0.0026 0.0437
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0049 0.0083 0.0244
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0037 0.0049 0.0138
Echinococcus granulosus geminin 0.017 0.0424 0.1302
Mycobacterium tuberculosis Probable oxidoreductase 0.0049 0.0083 0.0069
Trypanosoma brucei short-chain dehydrogenase, putative 0.0049 0.0083 0.0244
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0424 0.2128
Loa Loa (eye worm) hypothetical protein 0.0056 0.0103 0.0319
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0967 0.2677 0.2667
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0049 0.0083 0.0069
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0049 0.0083 0.0069
Plasmodium falciparum subtilisin-like protease 3 0.0025 0.0014 0.0199
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0676 0.3403
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0049 0.0083 0.0398
Entamoeba histolytica prolyl oligopeptidase family protein 0.0196 0.0497 0.3049
Mycobacterium ulcerans esterase/lipase LipP 0.0183 0.0462 0.0449
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0143 0.0432
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0593 0.1621 1
Mycobacterium leprae Probable oxidoreductase 0.0049 0.0083 0.05
Leishmania major hypothetical protein, conserved 0.0049 0.0083 0.0244
Echinococcus granulosus acylamino acid releasing enzyme 0.0196 0.0497 0.1528
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Plasmodium falciparum peptidase, putative 0.0196 0.0497 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0049 0.0083 0.0398
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0098 0.0305
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0049 0.0083 0.0398
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0049 0.0083 0.0069
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0517 0.1406 0.4346
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0463 0.1252 0.3877
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0116 0.0347
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0424 0.2128
Loa Loa (eye worm) hypothetical protein 0.025 0.0651 0.2015
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0025 0.0014 0.003
Onchocerca volvulus 0.0049 0.0083 0.0256
Echinococcus multilocularis p2X purinoceptor 4 0.0071 0.0144 0.0435
Schistosoma mansoni hypothetical protein 0.0056 0.0103 0.0307
Toxoplasma gondii oxidoreductase, putative 0.0049 0.0083 0.0256
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0083 0.0486
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0083 0.0244
Echinococcus granulosus p2X purinoceptor 4 0.0071 0.0144 0.0435
Brugia malayi Dehydrogenases, short chain protein 2 0.0049 0.0083 0.0256
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Brugia malayi hypothetical protein 0.0049 0.0083 0.0256
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0025 0.0014 0.003
Trypanosoma brucei prolyl endopeptidase 0.1162 0.323 1
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0196 0.0497 0.1528
Mycobacterium ulcerans hypothetical protein 0.0183 0.0462 0.0449
Loa Loa (eye worm) hypothetical protein 0.0223 0.0574 0.1778
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0024 0.0074
Loa Loa (eye worm) subtilase 0.0801 0.2208 0.6835
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0512 0.1391 0.4299
Loa Loa (eye worm) hypothetical protein 0.0719 0.1976 0.6117
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0016 0.0247
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0049 0.0083 0.0069
Brugia malayi Bromodomain containing protein 0.0028 0.0024 0.0074
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Toxoplasma gondii PAN domain-containing protein 0.0308 0.0816 0.2525
Echinococcus multilocularis p2X purinoceptor 4 0.0071 0.0144 0.0435
Loa Loa (eye worm) glutaminase 2 0.0555 0.1513 0.4683
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0273 0.0846
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0098 0.0293
Loa Loa (eye worm) hypothetical protein 0.0183 0.0462 0.143
Onchocerca volvulus 0.0049 0.0083 0.0256
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0512 0.1391 0.4299
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0249 0.0649 0.1998
Schistosoma mansoni hypothetical protein 0.0308 0.0816 0.2517
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0249 0.0649 0.1998
Brugia malayi oxidoreductase 0.0049 0.0083 0.0256
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0025 0.0014 0.003
Brugia malayi Trypsin family protein 0.0223 0.0574 0.1778
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0025 0.0014 0.003
Trypanosoma brucei short-chain dehydrogenase, putative 0.0049 0.0083 0.0244
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0049 0.0083 0.0256
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0049 0.0083 0.0398
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0049 0.0228
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0049 0.0083 0.0256
Loa Loa (eye worm) dehydrogenase 0.0049 0.0083 0.0256
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.1621 0.8196
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0189 0.0478 0.1481
Echinococcus multilocularis 0.0025 0.0014 0.003
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0512 0.1391 0.1379
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0189 0.0478 0.147
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0049 0.0138
Schistosoma mansoni steroid dehydrogenase 0.0049 0.0083 0.0244
Onchocerca volvulus 0.0037 0.0049 0.015
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0049 0.0083 0.1595
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0049 0.0083 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0014 0.005
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0037 0.0049 0.015
Trypanosoma cruzi hypothetical protein, conserved 0.0196 0.0497 0.1528
Brugia malayi hypothetical protein 0.0026 0.0016 0.005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.001 0.0031
Leishmania major 3-keto-dihydrosphingosine reductase 0.0049 0.0083 0.0244
Loa Loa (eye worm) hypothetical protein 0.0091 0.02 0.062
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0016 0.0247
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0189 0.0478 0.147
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0024 0.0062
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0098 0.0293
Brugia malayi Cytochrome P450 family protein 0.0026 0.0018 0.0056
Loa Loa (eye worm) prolyl oligopeptidase 0.0196 0.0497 0.1539
Brugia malayi celfurPC protein 0.0025 0.0014 0.0043
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0049 0.0083 0.0244
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0196 0.0497 0.1528
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0676 0.3403
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0137 0.0331 0.1025
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.001 0.0031
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1162 0.323 1
Leishmania major hypothetical protein, conserved 0.0026 0.0016 0.0038
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.015
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0331 0.1014
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0049 0.0083 0.0244
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0049 0.0083 0.05
Brugia malayi prolyl oligopeptidase family protein 0.1162 0.323 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0512 0.1391 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0098 0.0293
Entamoeba histolytica hypothetical protein 0.0071 0.0143 0.0862
Leishmania major hypothetical protein, conserved 0.0049 0.0083 0.0244
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0049 0.0083 0.0244
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1162 0.323 1
Echinococcus multilocularis steroid dehydrogenase 0.0049 0.0083 0.0244
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0049 0.0083 0.0244
Leishmania major hypothetical protein, conserved 0.0056 0.0103 0.0307
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0259 0.0676 0.2091
Toxoplasma gondii PAN domain-containing protein 0.0308 0.0816 0.2525
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0116 0.0347
Entamoeba histolytica hypothetical protein, conserved 0.0196 0.0497 0.3049
Loa Loa (eye worm) hypothetical protein 0.0223 0.0574 0.1778
Mycobacterium ulcerans ketoacyl reductase 0.0049 0.0083 0.0069
Trypanosoma brucei prolyl oligopeptidase, putative 0.0512 0.1391 0.4299
Loa Loa (eye worm) inositol-1 0.0037 0.0049 0.0152
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0085 0.0264
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Brugia malayi RNA, U transporter 1 0.0082 0.0176 0.0546
Onchocerca volvulus 0.0049 0.0083 0.0256
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Onchocerca volvulus 0.0049 0.0083 0.0256
Loa Loa (eye worm) hypothetical protein 0.0367 0.0983 0.3042
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.02 0.0608
Echinococcus granulosus steroid dehydrogenase 0.0049 0.0083 0.0244
Giardia lamblia Fructose-bisphosphate aldolase 0.0593 0.1621 1
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0249 0.0649 0.1998
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Mycobacterium tuberculosis Probable lipase LipE 0.0183 0.0462 0.0449
Trichomonas vaginalis steroid dehydrogenase, putative 0.0049 0.0083 0.0398
Brugia malayi hypothetical protein 0.0267 0.0699 0.2164
Brugia malayi Trypsin-like protease protein 5 0.0037 0.0049 0.015
Echinococcus multilocularis transmembrane protease serine 3 0.0037 0.0049 0.0138
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0183 0.0462 0.0449
Mycobacterium leprae Probable lipase LipE 0.0183 0.0462 0.3253
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0016 0.0247
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0049 0.0083 0.0398
Trypanosoma cruzi subtilisin peptidase 0.0025 0.0014 0.003
Trypanosoma cruzi prolyl endopeptidase 0.1162 0.323 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0041 0.0114
Brugia malayi Dehydrogenases, short chain protein 30 0.0049 0.0083 0.0256
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0049 0.0083 0.0069
Mycobacterium tuberculosis Possible oxidoreductase 0.0049 0.0083 0.0069
Trichomonas vaginalis penicillin-binding protein, putative 0.0183 0.0462 0.232
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0816 0.2251 0.6965
Brugia malayi Importin beta-1 subunit 0.0029 0.0026 0.0079
Brugia malayi Retinol dehydrogenase 12 0.0049 0.0083 0.0256
Echinococcus granulosus retinol dehydrogenase 11 0.0049 0.0083 0.0244
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0183 0.0462 0.143
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.0424 0.1313
Schistosoma mansoni hypothetical protein 0.0037 0.0049 0.0138
Plasmodium vivax subtilisin-like serine protease, putative 0.0025 0.0014 0.0199
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0016 0.0038
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0025 0.0014 0.0043
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Trypanosoma brucei short-chain dehydrogenase, putative 0.0049 0.0083 0.0244
Onchocerca volvulus 0.0223 0.0574 0.1778
Onchocerca volvulus 0.0049 0.0083 0.0256
Loa Loa (eye worm) hypothetical protein 0.0189 0.0478 0.1481
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0049 0.0139
Schistosoma mansoni caspase-7 (C14 family) 0.006 0.0114 0.0339
Mycobacterium ulcerans short-chain dehydrogenase 0.0049 0.0083 0.0069
Schistosoma mansoni carbonyl reductase 0.0049 0.0083 0.0244
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0183 0.0462 0.143
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0116 0.0102
Trypanosoma cruzi short chain dehydrogenase, putative 0.0049 0.0083 0.0244
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0143 0.0432
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.1621 0.8196
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0512 0.1391 0.1379
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0098 0.0293
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0055 0.0159
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Mycobacterium tuberculosis Conserved protein 0.0183 0.0462 0.0449
Echinococcus granulosus retinol dehydrogenase 11 0.0049 0.0083 0.0244
Echinococcus multilocularis glycoprotein Antigen 5 0.0037 0.0049 0.0138
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0049 0.0083 0.0244
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0024 0.0074
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.005
Mycobacterium ulcerans short-chain dehydrogenase 0.0049 0.0083 0.0069
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0049 0.0083 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0041 0.0114
Trypanosoma cruzi prefoldin subunit, putative 0.0063 0.0121 0.0364
Onchocerca volvulus 0.0025 0.0014 0.0043
Leishmania major importin beta-1 subunit, putative 0.0023 0.001 0.0019
Plasmodium vivax hypothetical protein, conserved 0.0196 0.0497 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Echinococcus granulosus furin 0.0025 0.0014 0.003
Mycobacterium ulcerans glutaminase 0.0555 0.1513 0.1501
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0049 0.0083 0.0256
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.02 0.0608
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.008 0.0246
Schistosoma mansoni hypothetical protein 0.0189 0.0478 0.147
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.015
Loa Loa (eye worm) hypothetical protein 0.0048 0.008 0.0246
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Onchocerca volvulus 0.0056 0.0103 0.0319
Onchocerca volvulus 0.006 0.0114 0.0351
Echinococcus multilocularis transient receptor potential cation channel 0.0049 0.0083 0.0244
Brugia malayi beta-lactamase family protein 0.0183 0.0462 0.143
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0331 0.1014
Leishmania major quinonoid dihydropteridine reductase 0.0049 0.0083 0.0244
Loa Loa (eye worm) hypothetical protein 0.0063 0.0121 0.0376
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0049 0.0083 0.0486
Trichomonas vaginalis glutaminase, putative 0.0555 0.1513 0.7646
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0049 0.0083 0.0256
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0085 0.0264
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0424 0.2128
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0424 0.2128
Echinococcus multilocularis prefoldin subunit 6 0.0063 0.0121 0.0364
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.006 0.0114 0.0351
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Toxoplasma gondii prefoldin subunit 6, putative 0.0063 0.0121 0.0376
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0049 0.0228
Toxoplasma gondii subtilisin SUB6 0.0025 0.0014 0.0043
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0049 0.0139
Onchocerca volvulus 0.0183 0.0462 0.143
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0049 0.0083 0.0244
Toxoplasma gondii oxidoreductase, putative 0.0049 0.0083 0.0256
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Mycobacterium ulcerans carveol-like dehydrogenase 0.0049 0.0083 0.0069
Plasmodium falciparum steroid dehydrogenase, putative 0.0049 0.0083 0.1595
Leishmania major hypothetical protein, conserved 0.0049 0.0083 0.0244
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0083 0.0069
Onchocerca volvulus 0.0091 0.02 0.062
Mycobacterium ulcerans oxidoreductase 0.0049 0.0083 0.0069
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.001 0.0019
Schistosoma mansoni hypothetical protein 0.0296 0.078 0.2404
Echinococcus multilocularis neuroendocrine convertase 2 0.0025 0.0014 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0083 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0196 0.0497 0.2499
Trypanosoma cruzi oligopeptidase b 0.0512 0.1391 0.4299
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0049 0.0138
Giardia lamblia Hypothetical protein 0.0049 0.0083 0.0486
Mycobacterium leprae conserved hypothetical protein 0.0183 0.0462 0.3253
Loa Loa (eye worm) TK/ROR protein kinase 0.0056 0.0103 0.0319
Schistosoma mansoni hypothetical protein 0.017 0.0424 0.1302
Echinococcus multilocularis p2X purinoceptor 4 0.0071 0.0144 0.0435
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0183 0.0462 0.0449
Echinococcus granulosus prolyl endopeptidase 0.1162 0.323 1
Giardia lamblia Short-chain dehydrogenase, putative 0.0049 0.0083 0.0486
Trichomonas vaginalis importin beta-1, putative 0.0023 0.001 0.0031
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0049 0.0083 0.0069
Entamoeba histolytica hypothetical protein 0.0071 0.0143 0.0862
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0049 0.0083 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0014 0.005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Loa Loa (eye worm) MBCTL1 0.0055 0.0098 0.0305
Echinococcus granulosus carbonyl reductase 1 0.0049 0.0083 0.0244
Echinococcus multilocularis retinol dehydrogenase 11 0.0049 0.0083 0.0244
Giardia lamblia Hypothetical protein 0.0063 0.0121 0.0726
Trypanosoma brucei subtilisin peptidase 0.0025 0.0014 0.003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0083 0.0256
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.008 0.0234
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0037 0.0049 0.0138
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0049 0.0083 0.0256
Echinococcus multilocularis inhibitor of apoptosis protein 0.0189 0.0478 0.147
Trypanosoma brucei short-chain dehydrogenase, putative 0.0049 0.0083 0.0244
Onchocerca volvulus 0.0048 0.008 0.0246
Loa Loa (eye worm) oxidoreductase 0.0049 0.0083 0.0256
Schistosoma mansoni short chain dehydrogenase 0.0049 0.0083 0.0244
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0196 0.0497 0.1539
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0256
Toxoplasma gondii ABC1 family protein 0.0183 0.0462 0.143
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0196 0.0497 0.2499
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.1621 0.8196
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0083 0.0069
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0025 0.0014 0.005
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0259 0.0676 0.2091
Mycobacterium ulcerans ketoacyl reductase 0.0049 0.0083 0.0069
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0049 0.0083 0.0244
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.015
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0049 0.0138
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0049 0.0083 0.0244
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.029 0.0763 0.0751

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 11.65 uM Cytotoxicity against human HL60 cells after 2 days by MTT assay ChEMBL. 18296054
IC50 (functional) > 25 uM Cytotoxicity against human MCF7 cells after 2 days by MTT assay ChEMBL. 18296054

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 18296054

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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