Detailed information for compound 1022158

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 361.889 | Formula: C18H20ClN3OS
  • H donors: 3 H acceptors: 0 LogP: 3.72 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: S=C(NC1CC(C)(C)Oc2c1cc(N)cc2)Nc1ccc(cc1)Cl
  • InChi: 1S/C18H20ClN3OS/c1-18(2)10-15(14-9-12(20)5-8-16(14)23-18)22-17(24)21-13-6-3-11(19)4-7-13/h3-9,15H,10,20H2,1-2H3,(H2,21,22,24)
  • InChiKey: ABBPXIQTEGAQTC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.008 0.0571 0.0571
Trichomonas vaginalis tubulin gamma chain, putative 0.0807 0.6944 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0098 0.0731 0.1053
Loa Loa (eye worm) hypoxia-induced factor 1 0.0156 0.1237 0.1237
Schistosoma mansoni microtubule-associated protein tau 0.0807 0.694 0.7444
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0416 0.0446
Trypanosoma cruzi tubulin delta chain 0.0188 0.1519 0.2187
Schistosoma mansoni hypothetical protein 0.1079 0.9323 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0245 0.2019 0.2907
Onchocerca volvulus 0.0203 0.1646 0.3913
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0044 0.0063
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.1341 0.1438
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.005 0.031 0.2042
Schistosoma mansoni nAChR subunit 0.0203 0.1646 0.1765
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0723 0.1041
Trypanosoma brucei beta tubulin 0.0433 0.3668 0.5282
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0356 0.2988 0.4304
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0203 0.1646 0.237
Schistosoma mansoni calcium-activated potassium channel 0.0291 0.2416 0.2592
Loa Loa (eye worm) tubulin beta-1 chain 0.0807 0.6944 0.6944
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0187 0.0269
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0196 0.0282
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0046 0.005
Loa Loa (eye worm) tubulin alpha 2 0.0168 0.1339 0.1339
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.005 0.031 0.0713
Schistosoma mansoni axis inhibition protein axin 0.002 0.0044 0.0047
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.005 0.031 0.2042
Schistosoma mansoni hypothetical protein 0.0038 0.0206 0.0221
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0723 0.1718
Echinococcus multilocularis Tubulin beta 2C chain 0.0807 0.6944 0.7447
Loa Loa (eye worm) hypothetical protein 0.0104 0.0784 0.0784
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0047 0.0282 0.0282
Echinococcus granulosus Tubulin beta 2C chain 0.0807 0.6944 0.7447
Trypanosoma brucei alpha tubulin, putative 0.0245 0.2019 0.2907
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0187 0.0269
Trypanosoma cruzi beta tubulin, putative 0.0807 0.6944 1
Echinococcus granulosus tubulin alpha 3 chain 0.0601 0.5137 0.551
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0044 0.0063
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0239 0.196 0.4507
Brugia malayi hypothetical protein 0.0098 0.0731 0.1053
Plasmodium vivax hypothetical protein, conserved 0.008 0.0571 0.0822
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0203 0.1646 0.1765
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0203 0.1646 0.237
Brugia malayi cytoplasmic intermediate filament protein 0.0047 0.0282 0.0406
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0203 0.1646 0.237
Trypanosoma brucei zeta tubulin 0.0188 0.1519 0.2187
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0044 0.0047
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0044 0.0044
Entamoeba histolytica tubulin alpha chain, putative 0.0601 0.5137 0.7399
Schistosoma mansoni regulator of G protein signaling 0.002 0.0044 0.0047
Echinococcus multilocularis lamin dm0 0.0088 0.0639 0.0686
Loa Loa (eye worm) alpha-tubulin 0.0601 0.5137 0.5137
Leishmania major DNA polymerase eta, putative 0.002 0.0044 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0044
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0043 0.0099
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0571 0.0822
Trypanosoma brucei tubulin gamma chain 0.0433 0.3668 0.5282
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0723 0.1041
Loa Loa (eye worm) tubulin alpha-3 chain 0.0356 0.2988 0.2988
Trichomonas vaginalis bromodomain-containing protein, putative 0.0095 0.0702 0.1011
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0014 0.0021
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0044 0.0101
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0203 0.1646 0.1765
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0187 0.0269
Entamoeba histolytica hypothetical protein 0.0042 0.024 0.0346
Trypanosoma brucei polo-like protein kinase 0.0097 0.0723 0.1041
Schistosoma mansoni hypothetical protein 0.0042 0.024 0.0257
Onchocerca volvulus 0.0088 0.0639 0.152
Loa Loa (eye worm) cytochrome P450 0.005 0.031 0.031
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0041 0.0059
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0723 0.0723
Loa Loa (eye worm) intermediate filament protein 0.0088 0.0639 0.0639
Echinococcus multilocularis lamin 0.0088 0.0639 0.0686
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0045 0.0065
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0311 0.0334
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0196 0.0282
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0203 0.1646 0.237
Schistosoma mansoni nAChR subunit 0.0203 0.1646 0.1765
Schistosoma mansoni nAChR subunit 0.0203 0.1646 0.1765
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.005 0.031 0.0713
Treponema pallidum cell division protein FtsZ 0.0188 0.1519 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0041 0.0044
Brugia malayi Tubulin beta chain 0.0188 0.1519 0.2187
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0044
Trypanosoma brucei PAB1-binding protein , putative 0.0086 0.062 0.0893
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0187 0.0269
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0188 0.1519 0.2187
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0098 0.0731 0.0784
Trypanosoma brucei hypothetical protein, conserved 0.008 0.0571 0.0822
Loa Loa (eye worm) hypothetical protein 0.0363 0.3052 0.3052
Schistosoma mansoni neurotransmitter gated ion channel 0.0098 0.0731 0.0784
Brugia malayi Glycosyl hydrolases family 31 protein 0.0168 0.1341 0.1931
Leishmania major beta tubulin 0.0807 0.6944 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0807 0.6944 0.7447
Schistosoma mansoni lamin 0.0088 0.0639 0.0686
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0044 0.0063
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0203 0.1646 0.1646
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0196 0.0282
Toxoplasma gondii alpha-tubulin I, putative 0.0601 0.5137 0.7399
Schistosoma mansoni tubulin subunit alpha 0.0601 0.5137 0.551
Echinococcus granulosus Tubulin alpha 1 chain 0.0601 0.5137 0.551
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0046 0.0046
Brugia malayi Tubulin alpha-2 chain 0.0601 0.5137 0.7399
Mycobacterium ulcerans esterase/lipase LipP 0.008 0.0571 0.3757
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0187 0.0269
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0043 0.0062
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0723 0.1041
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0044 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0187 0.0269
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.0571 0.0822
Echinococcus granulosus microtubule associated protein 2 0.0807 0.694 0.7444
Giardia lamblia Epsilon tubulin 0.0188 0.1519 0.2187
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0044 0.0047
Trichomonas vaginalis tubulin gamma chain, putative 0.0188 0.1519 0.2187
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0043 0.0062
Brugia malayi Ets-domain containing protein 0.0076 0.0534 0.0769
Trypanosoma cruzi zeta tubulin, putative 0.0188 0.1519 0.2187
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.005 0.031 0.0713
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0088 0.0639 0.0639
Mycobacterium ulcerans beta-lactamase 0.008 0.0571 0.3757
Entamoeba histolytica hypothetical protein 0.002 0.0044 0.0063
Schistosoma mansoni tubulin subunit beta 0.0188 0.1519 0.1629
Echinococcus granulosus tubulin beta 1 chain 0.0807 0.6944 0.7447
Echinococcus multilocularis dna polymerase eta 0.002 0.0044 0.0047
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0098 0.0731 0.1053
Entamoeba histolytica tubulin family protein 0.0807 0.6944 1
Schistosoma mansoni alpha glucosidase 0.0037 0.0196 0.021
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.005 0.031 0.2042
Brugia malayi Cytochrome P450 family protein 0.0175 0.1402 0.2019
Plasmodium falciparum tubulin gamma chain 0.0433 0.3668 0.5282
Loa Loa (eye worm) tubulin beta chain 0.0188 0.1519 0.1519
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0039 0.021 0.021
Schistosoma mansoni hypothetical protein 0.1079 0.9323 1
Echinococcus granulosus lamin 0.0088 0.0639 0.0686
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0043 0.0062
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0187 0.0201
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0015
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.1517 0.2185
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0323 0.27 0.2895
Loa Loa (eye worm) hypothetical protein 0.0042 0.0241 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0188 0.1519 0.2187
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0014 0.0021
Mycobacterium tuberculosis Conserved protein 0.008 0.0571 0.1312
Echinococcus multilocularis beta tubulin 0.0807 0.6944 0.7447
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0098 0.0731 0.1053
Trichomonas vaginalis tubulin beta chain, putative 0.0245 0.2019 0.2907
Schistosoma mansoni regulator of G protein signaling 0.002 0.0044 0.0047
Brugia malayi hypothetical protein 0.002 0.0044 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0187 0.0269
Brugia malayi tubulin alpha chain - mouse 0.0601 0.5137 0.7399
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0203 0.1646 0.1765
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0098 0.0731 0.0784
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0041 0.0059
Entamoeba histolytica tubulin gamma chain 0.0433 0.3668 0.5282
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0285 0.041
Schistosoma mansoni nAChR subunit 0.0203 0.1646 0.1765
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0044 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.2252 0.3243
Schistosoma mansoni hypothetical protein 0.0363 0.3052 0.3274
Giardia lamblia Histone acetyltransferase GCN5 0.0087 0.0632 0.0911
Schistosoma mansoni DNA helicase recq5 0.002 0.0041 0.0044
Loa Loa (eye worm) hypothetical protein 0.0034 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0104 0.0784 0.0784
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.005 0.031 0.2042
Echinococcus granulosus tubulin alpha chain 0.0601 0.5137 0.551
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Echinococcus multilocularis beta tubulin 0.0807 0.6944 0.7447
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0416 0.0446
Plasmodium vivax SET domain protein, putative 0.0062 0.0416 0.0599
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0187 0.0269
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0203 0.1646 0.1765
Schistosoma mansoni ets-related 0.023 0.1887 0.2024
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0292 0.042
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0089 0.0651 0.4284
Leishmania major beta tubulin 0.0807 0.6944 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0014 0.0021
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0196 0.0282
Schistosoma mansoni calcium-activated potassium channel 0.0363 0.3052 0.3274
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0187 0.0269
Trichomonas vaginalis tubulin beta chain, putative 0.0601 0.5137 0.7399
Brugia malayi PXA domain containing protein 0.002 0.0044 0.0063
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0723 0.1041
Trypanosoma brucei epsilon tubulin 0.0433 0.3668 0.5282
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0203 0.1646 0.237
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0044
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0104 0.0784 0.0841
Echinococcus granulosus tubulin alpha chain 0.0601 0.5137 0.551
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.2252 0.3243
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0044 0.0047
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0196 0.0282
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0014 0.0015
Echinococcus granulosus Tubulin beta 2C chain 0.0807 0.6944 0.7447
Loa Loa (eye worm) hypothetical protein 0.0413 0.3488 0.3488
Brugia malayi PAS domain containing protein 0.005 0.0311 0.0448
Onchocerca volvulus 0.0245 0.2019 0.48
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0196 0.0282
Echinococcus multilocularis peroxisome assembly protein 26 0.0601 0.5137 0.551
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0187 0.0269
Trichomonas vaginalis tubulin, putative 0.0807 0.6944 1
Trypanosoma brucei beta tubulin 0.0807 0.6944 1
Plasmodium falciparum alpha tubulin 1 0.0601 0.5137 0.7399
Entamoeba histolytica tubulin family protein 0.0807 0.6944 1
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0571 0.0822
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Echinococcus granulosus tubulin alpha 1C chain 0.0601 0.5137 0.551
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0044 0.0047
Loa Loa (eye worm) hypothetical protein 0.0058 0.0375 0.0375
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Loa Loa (eye worm) BEN-1 protein 0.0807 0.6944 0.6944
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0044 0.0047
Leishmania major beta tubulin 0.0807 0.6944 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0104 0.0784 0.1129
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Leishmania major beta tubulin 0.0807 0.6944 1
Schistosoma mansoni alpha tubulin 0.0601 0.5137 0.551
Echinococcus granulosus tubulin delta chain 0.0188 0.1519 0.1629
Plasmodium vivax tubulin alpha chain, putative 0.0601 0.5137 0.7399
Echinococcus granulosus nAChR subunit 0.0203 0.1646 0.1765
Trypanosoma brucei beta tubulin 0.0807 0.6944 1
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0413 0.3488 0.3488
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.2252 0.3243
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0187 0.0269
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0203 0.1646 0.1765
Echinococcus granulosus tubulin alpha 0.0433 0.3668 0.3934
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Giardia lamblia Alpha-tubulin 0.0601 0.5137 0.7399
Schistosoma mansoni cytochrome P450 0.005 0.031 0.0333
Plasmodium falciparum histone acetyltransferase GCN5 0.0087 0.0632 0.0911
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0044 0.0063
Trichomonas vaginalis tubulin alpha chain, putative 0.0807 0.6944 1
Echinococcus granulosus glycine receptor subunit beta 0.0203 0.1646 0.1765
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0091 0.0132
Leishmania major beta tubulin 0.0807 0.6944 1
Giardia lamblia Beta tubulin 0.0807 0.6944 1
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0203 0.1646 0.1765
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0203 0.1646 0.1765
Echinococcus multilocularis microtubule associated protein 2 0.0807 0.694 0.7444
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0044 0.0047
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0203 0.1646 0.1765
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0196 0.0196
Toxoplasma gondii beta-1 tubulin, putative 0.0807 0.6944 1
Trypanosoma brucei glucosidase, putative 0.0037 0.0196 0.0282
Trichomonas vaginalis tubulin alpha chain, putative 0.0245 0.2019 0.2907
Entamoeba histolytica tubulin alpha-1 chain 0.0601 0.5137 0.7399
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0041 0.0059
Onchocerca volvulus 0.0203 0.1646 0.3913
Loa Loa (eye worm) hypothetical protein 0.0609 0.5207 0.5207
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.005 0.031 0.2042
Leishmania major trypanothione reductase 0.0105 0.0786 0.1132
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0489 0.4155 0.4155
Leishmania major beta tubulin 0.0807 0.6944 1
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0707 0.6069 0.874
Entamoeba histolytica hypothetical protein 0.0042 0.024 0.0346
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0234 0.0338
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0601 0.5137 0.7399
Loa Loa (eye worm) LGC-31 protein 0.0203 0.1646 0.1646
Echinococcus granulosus tubulin gamma 1 chain 0.0433 0.3668 0.3934
Trypanosoma brucei tubulin delta chain 0.0188 0.1519 0.2187
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0014 0.0021
Brugia malayi hypothetical protein 0.0276 0.2292 0.3301
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0416 0.0446
Echinococcus granulosus survival motor neuron protein 1 0.0276 0.2292 0.2459
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0043 0.0062
Echinococcus multilocularis tubulin alpha chain 0.0601 0.5137 0.551
Entamoeba histolytica hypothetical protein 0.0042 0.024 0.0346
Leishmania major epsilon tubulin, putative 0.0433 0.3668 0.5282
Brugia malayi intermediate filament protein 0.0088 0.0639 0.0921
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0015
Loa Loa (eye worm) tubulin gamma chain 0.0433 0.3668 0.3668
Onchocerca volvulus Putative nachr subunit 0.0203 0.1646 0.3913
Brugia malayi hypothetical protein 0.002 0.0044 0.0063
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.056 0.4778 0.6881
Giardia lamblia Beta tubulin 0.0807 0.6944 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.021 0.0302
Loa Loa (eye worm) RecQ helicase 0.0047 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.008 0.0571 0.0571
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0239 0.196 0.4507
Echinococcus granulosus tubulin alpha chain 0.0601 0.5137 0.551
Loa Loa (eye worm) hypothetical protein 0.008 0.0571 0.0571
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0095 0.0702 0.1011
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.005 0.031 0.0713
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Brugia malayi Tubulin alpha-2 chain 0.0601 0.5137 0.7399
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.005 0.031 0.2042
Brugia malayi Cation transporter family protein 0.0203 0.1646 0.237
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0038 0.0206 0.0221
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0076 0.0534 0.0534
Leishmania major protein kinase, putative 0.0019 0.0032 0.0046
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0187 0.0976
Echinococcus granulosus tubulin alpha chain 0.0601 0.5137 0.551
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0854 0.735 0.7884
Toxoplasma gondii beta tubulin 0.0807 0.6944 1
Brugia malayi glutathione reductase 0.0105 0.0786 0.1132
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0044 0.0063
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0239 0.196 0.8761
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0723 0.0775
Schistosoma mansoni nAChR subunit 0.0098 0.0731 0.0784
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.005 0.031 0.0713
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0044 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1433 0.2063
Brugia malayi hypothetical protein 0.0055 0.0354 0.051
Loa Loa (eye worm) hypothetical protein 0.0276 0.2292 0.2292
Brugia malayi hypothetical protein 0.0042 0.024 0.0346
Echinococcus granulosus axis inhibition protein axin 0.002 0.0044 0.0047
Mycobacterium tuberculosis Conserved protein 0.008 0.0571 0.1312
Schistosoma mansoni tubulin subunit alpha 0.0188 0.1519 0.1629
Loa Loa (eye worm) glutathione reductase 0.0105 0.0786 0.0786
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Plasmodium falciparum glutathione reductase 0.0036 0.0187 0.0269
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0396 0.0425
Trypanosoma brucei alpha tubulin 0.0601 0.5137 0.7399
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0044 0.0047
Echinococcus multilocularis Tubulin beta 2C chain 0.0807 0.6944 0.7447
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0201 0.0201
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.005 0.031 0.0713
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0723 0.1041
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0187 0.1231
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0046 0.005
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.024 0.0257
Trypanosoma cruzi cytochrome P450, putative 0.0089 0.0651 0.0937
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0044 0.0063
Schistosoma mansoni tubulin subunit beta 0.0807 0.6944 0.7447
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0044 0.0288
Echinococcus granulosus beta tubulin 0.0807 0.6944 0.7447
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0044 0.0044
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Echinococcus granulosus histone acetyltransferase KAT2B 0.0095 0.0702 0.0753
Loa Loa (eye worm) hypothetical protein 0.0104 0.0784 0.0784
Plasmodium falciparum ataxin-2 like protein, putative 0.0086 0.062 0.0893
Leishmania major delta tubulin, putative 0.0188 0.1519 0.2187
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0147 0.0212
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.005 0.031 0.2042
Onchocerca volvulus Glucosylceramidase homolog 0.0178 0.1433 0.3407
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0041 0.0059
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0723 0.1041
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Plasmodium vivax delta tubulin, putative 0.0188 0.1519 0.2187
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0723 0.1041
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0014 0.0021
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0044 0.0047
Brugia malayi Cation transporter family protein 0.0203 0.1646 0.237
Giardia lamblia Kinase, PLK 0.0097 0.0723 0.1041
Loa Loa (eye worm) hypothetical protein 0.0104 0.0784 0.0784
Echinococcus multilocularis geminin 0.1079 0.9323 1
Loa Loa (eye worm) hypothetical protein 0.0356 0.2988 0.2988
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0098 0.0731 0.0784
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0015
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.0103 0.0148
Leishmania major beta tubulin 0.0807 0.6944 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0086 0.062 0.0893
Echinococcus granulosus Tubulin alpha 1 chain 0.0601 0.5137 0.551
Brugia malayi isocitrate dehydrogenase 0.0017 0.0014 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.005 0.031 0.0713
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0196 0.021
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.008 0.0571 0.1312
Brugia malayi hypothetical protein 0.0126 0.0975 0.1404
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0571 0.0822
Schistosoma mansoni tubulin subunit beta 0.0807 0.6944 0.7447
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Brugia malayi Tubulin alpha chain 0.0601 0.5137 0.7399
Loa Loa (eye worm) ACC-1 protein 0.0203 0.1646 0.1646
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0044 0.0063
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0043 0.0046
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.1341 0.1438
Trypanosoma cruzi cytochrome p450-like protein, putative 0.005 0.031 0.0447
Plasmodium vivax thioredoxin reductase, putative 0.0105 0.0786 0.1132
Leishmania major beta tubulin 0.0807 0.6944 1
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.005 0.031 0.2042
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0285 0.041
Mycobacterium tuberculosis Probable esterase LipL 0.008 0.0571 0.1312
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.005 0.031 0.2042
Leishmania major beta tubulin 0.0807 0.6944 1
Trichomonas vaginalis set domain proteins, putative 0.0495 0.4206 0.6057
Loa Loa (eye worm) tubulin beta-2A chain 0.0807 0.6944 0.6944
Echinococcus granulosus nAChR subunit 0.0104 0.0784 0.0841
Leishmania major beta tubulin 0.0807 0.6944 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Trypanosoma cruzi alpha tubulin, putative 0.0601 0.5137 0.7399
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0203 0.1646 0.1765
Echinococcus granulosus glycine receptor subunit alpha 1 0.0203 0.1646 0.1765
Loa Loa (eye worm) tubulin alpha chain 0.0601 0.5137 0.5137
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0188 0.1519 0.2187
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Echinococcus granulosus tubulin beta 4A class IVa 0.0807 0.6944 0.7447
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0571 0.0822
Schistosoma mansoni DNA helicase recq1 0.002 0.0041 0.0044
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0044 0.0047
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0196 0.0283
Trypanosoma brucei trypanothione reductase 0.0105 0.0786 0.1132
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0723 0.0775
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Giardia lamblia DINP protein human, muc B family 0.002 0.0044 0.0063
Brugia malayi beta-lactamase family protein 0.008 0.0571 0.0822
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Loa Loa (eye worm) tubulin beta chain 0.0807 0.6944 0.6944
Leishmania major lanosterol 14-alpha-demethylase, putative 0.005 0.031 0.0447
Loa Loa (eye worm) tubulin alpha 2 0.0413 0.3488 0.3488
Onchocerca volvulus 0.0097 0.0721 0.1713
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0198 0.0212
Loa Loa (eye worm) cytochrome P450 family protein 0.0089 0.0651 0.0651
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0044
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0187 0.0976
Echinococcus granulosus bloom syndrome protein 0.0047 0.0285 0.0306
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0051 0.0318 0.0458
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0723 0.1041
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Echinococcus granulosus GA binding protein alpha chain 0.0076 0.0534 0.0573
Mycobacterium tuberculosis Conserved protein 0.008 0.0571 0.1312
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1433 0.2063
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0203 0.1646 0.1765
Onchocerca volvulus 0.008 0.0571 0.1357
Schistosoma mansoni nAChR subunit 0.0203 0.1646 0.1765
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.005 0.031 0.2042
Trichomonas vaginalis tubulin epsilon chain, putative 0.0807 0.6944 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0044 0.0047
Leishmania major beta tubulin 0.0807 0.6944 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0044 0.0063
Loa Loa (eye worm) acetylcholine receptor protein 0.0098 0.0731 0.0731
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.005 0.031 0.0713
Echinococcus multilocularis thioredoxin glutathione reductase 0.0105 0.0786 0.0843
Trypanosoma cruzi PAB1-binding protein , putative 0.0086 0.062 0.0893
Brugia malayi Ets-domain containing protein 0.0076 0.0534 0.0769
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0196 0.0282
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0196 0.1293
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0196 0.0282
Echinococcus granulosus Tubulin beta 2C chain 0.0807 0.6944 0.7447
Loa Loa (eye worm) hypothetical protein 0.0041 0.0227 0.0227
Echinococcus multilocularis tubulin delta chain 0.0188 0.1519 0.1629
Mycobacterium tuberculosis Probable dehydrogenase 0.0239 0.196 0.4507
Leishmania major beta tubulin 0.0807 0.6944 1
Toxoplasma gondii LsmAD domain-containing protein 0.0086 0.062 0.0893
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0046 0.0046
Giardia lamblia Delta tubulin 0.0188 0.1519 0.2187
Trypanosoma brucei alpha tubulin 0.0601 0.5137 0.7399
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0413 0.3488 0.5024
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0044 0.0047
Echinococcus granulosus lysosomal alpha glucosidase 0.0168 0.1341 0.1438
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0104 0.0784 0.1129
Loa Loa (eye worm) alpha-tubulin 0.0601 0.5137 0.5137
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0046 0.005
Brugia malayi acetyltransferase, GNAT family protein 0.0323 0.27 0.3888
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.005 0.031 0.2042
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.0571 0.0612
Echinococcus multilocularis tubulin alpha 3 chain 0.0601 0.5137 0.551
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0187 0.0269
Loa Loa (eye worm) ACC-1 protein 0.0203 0.1646 0.1646
Brugia malayi hypothetical protein 0.0098 0.0731 0.1053
Echinococcus multilocularis tubulin gamma 1 chain 0.0433 0.3668 0.3934
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0041
Brugia malayi Tubulin gamma chain 0.0433 0.3668 0.5282
Leishmania major gamma-tubulin 0.0433 0.3668 0.5282
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.008 0.0571 0.1312
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.005 0.031 0.2042
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.005 0.031 0.2042
Schistosoma mansoni DNA polymerase eta 0.002 0.0044 0.0047
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0043 0.0062
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0187 0.0269
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0203 0.1646 0.1765
Onchocerca volvulus 0.0098 0.0731 0.1738
Trichomonas vaginalis tubulin beta chain, putative 0.0807 0.6944 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0095 0.0702 0.1011
Onchocerca volvulus 0.0495 0.4206 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0203 0.1646 0.1765
Mycobacterium leprae conserved hypothetical protein 0.008 0.0571 0.1383
Mycobacterium tuberculosis Probable conserved lipoprotein 0.008 0.0571 0.1312
Leishmania major cytochrome p450-like protein 0.005 0.031 0.0447
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.005 0.031 0.2042
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0203 0.1646 0.1765
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0014 0.0021
Loa Loa (eye worm) BEN-1 protein 0.0807 0.6944 0.6944
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0043 0.0062
Loa Loa (eye worm) CYP4Cod1 0.0089 0.0651 0.0651
Brugia malayi Cation transporter family protein 0.0203 0.1646 0.237
Trichomonas vaginalis tubulin beta chain, putative 0.0601 0.5137 0.7399
Echinococcus granulosus histone acetyltransferase KAT2B 0.0314 0.262 0.281
Echinococcus multilocularis musashi 0.0088 0.0639 0.0686
Schistosoma mansoni regulator of G protein signaling 0.002 0.0044 0.0047
Trypanosoma cruzi cytochrome P450, putative 0.0089 0.0651 0.0937
Loa Loa (eye worm) hypothetical protein 0.0169 0.1351 0.1351
Onchocerca volvulus 0.0037 0.0196 0.0467
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0187 0.0269
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0098 0.0731 0.0784
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0041 0.0059
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.008 0.0571 0.3757
Echinococcus multilocularis tubulin alpha 1C chain 0.0601 0.5137 0.551
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0292 0.042
Trypanosoma brucei alpha tubulin 0.0601 0.5137 0.7399
Trichomonas vaginalis tubulin epsilon chain, putative 0.0601 0.5137 0.7399
Mycobacterium leprae Probable lipase LipE 0.008 0.0571 0.1383
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.005 0.031 0.2042
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0044 0.0063
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0196 0.0282
Trypanosoma cruzi zeta tubulin, putative 0.0188 0.1519 0.2187
Plasmodium falciparum tubulin beta chain 0.0807 0.6944 1
Schistosoma mansoni tubulin subunit beta 0.0807 0.6944 0.7447
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.005 0.031 0.0713
Giardia lamblia Gamma tubulin 0.0433 0.3668 0.5282
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.005 0.031 0.2042
Echinococcus multilocularis tubulin subunit TubB 0.0601 0.5137 0.551
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0091 0.0132
Echinococcus granulosus Tubulin beta 2C chain 0.0807 0.6944 0.7447
Brugia malayi Cytochrome P450 family protein 0.005 0.031 0.0447
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.005 0.031 0.0713
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0098 0.0731 0.0784
Plasmodium vivax ataxin-2 like protein, putative 0.0086 0.062 0.0893
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0014 0.0033
Echinococcus granulosus peroxisome assembly protein 26 0.0601 0.5137 0.551
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.005 0.031 0.0713
Echinococcus granulosus thioredoxin glutathione reductase 0.0105 0.0786 0.0843
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0723 0.0775
Echinococcus granulosus small conductance calcium activated potassium 0.0363 0.3052 0.3274
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0203 0.1646 0.1646
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0203 0.1646 0.237
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0196 0.0282
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.008 0.0571 0.0571
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1433 0.2063
Echinococcus granulosus tubulin alpha 1C chain 0.0601 0.5137 0.551
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0044 0.0063
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.0965 0.0965
Brugia malayi tubulin alpha-2 chain 0.0601 0.5137 0.7399
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0095 0.0702 0.1011
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0098 0.0731 0.1053
Loa Loa (eye worm) hypothetical protein 0.0088 0.0639 0.0639
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0187 0.0201
Onchocerca volvulus 0.0098 0.0731 0.1738
Schistosoma mansoni neurotransmitter gated ion channel 0.0104 0.0784 0.0841
Echinococcus granulosus lamin dm0 0.0088 0.0639 0.0686
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0014 0.0014
Loa Loa (eye worm) beta-lactamase 0.008 0.0571 0.0571
Loa Loa (eye worm) hypothetical protein 0.0041 0.0227 0.0227
Onchocerca volvulus 0.0203 0.1646 0.3913
Echinococcus granulosus geminin 0.1079 0.9323 1
Schistosoma mansoni tubulin subunit gamma 0.0433 0.3668 0.3934
Echinococcus multilocularis Tubulin beta 2C chain 0.0807 0.6944 0.7447
Echinococcus granulosus tubulin subunit beta 0.0807 0.6944 0.7447
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0091 0.0132
Schistosoma mansoni nAChR subunit 0.0203 0.1646 0.1765
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0203 0.1646 0.1765
Leishmania major beta tubulin 0.0807 0.6944 1
Echinococcus granulosus beta tubulin 0.0807 0.6944 0.7447
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0043 0.0283
Loa Loa (eye worm) acetyltransferase 0.0323 0.27 0.27
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Echinococcus granulosus Tubulin beta 2C chain 0.0807 0.6944 0.7447
Leishmania major beta tubulin 0.0807 0.6944 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0187 0.1231
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0203 0.1646 0.1646
Schistosoma mansoni alpha-glucosidase 0.0145 0.1136 0.1219
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0098 0.0731 0.0731
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0241 0.0259
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.008 0.0571 0.0822
Onchocerca volvulus 0.0098 0.0731 0.1738
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.021 0.021
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0187 0.043
Onchocerca volvulus 0.0104 0.0784 0.1865
Loa Loa (eye worm) hypothetical protein 0.0104 0.0784 0.0784
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1433 0.2063
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0104 0.0784 0.0841
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.1517 0.2185
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0044 0.0063
Trichomonas vaginalis tubulin beta chain, putative 0.0601 0.5137 0.7399
Plasmodium vivax tubulin gamma chain, putative 0.0433 0.3668 0.5282
Toxoplasma gondii cytochrome p450 superfamily protein 0.005 0.031 0.0447
Echinococcus granulosus expressed protein 0.0387 0.3259 0.3495
Toxoplasma gondii ABC1 family protein 0.008 0.0571 0.0822
Schistosoma mansoni lamin 0.0088 0.0639 0.0686
Loa Loa (eye worm) hypothetical protein 0.008 0.0571 0.0571
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0241 0.0259
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0045 0.0065
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1433 0.2063
Schistosoma mansoni regulator of G protein signaling 0.002 0.0044 0.0047
Plasmodium vivax tubulin alpha chain, putative 0.0601 0.5137 0.7399
Loa Loa (eye worm) cytochrome P450 family protein 0.0089 0.0651 0.0651
Giardia lamblia Alpha-tubulin 0.0601 0.5137 0.7399
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0188 0.1519 0.2187
Toxoplasma gondii exonuclease III APE 0.002 0.0043 0.0062
Echinococcus multilocularis tubulin alpha 0.0433 0.3668 0.3934
Schistosoma mansoni tubulin subunit beta 0.0807 0.6944 0.7447
Entamoeba histolytica hypothetical protein 0.002 0.0044 0.0063
Mycobacterium ulcerans lipase LipD 0.008 0.0571 0.3757
Echinococcus multilocularis hypothetical protein 0.0601 0.5137 0.551
Echinococcus multilocularis small conductance calcium activated potassium 0.0363 0.3052 0.3274
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.0571 0.0612
Trichomonas vaginalis tubulin alpha chain, putative 0.0433 0.3668 0.5282
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0272 0.2252 0.2252
Brugia malayi Tubulin beta chain 0.0245 0.2019 0.2907
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0098 0.0731 0.0731
Schistosoma mansoni kinase 0.0049 0.0303 0.0325
Schistosoma mansoni survival motor neuron protein 0.0056 0.0364 0.039
Echinococcus multilocularis Tubulin alpha 1 chain 0.0601 0.5137 0.551
Trypanosoma brucei alpha tubulin 0.0601 0.5137 0.7399
Mycobacterium tuberculosis Probable reductase 0.0239 0.196 0.4507
Trichomonas vaginalis tubulin epsilon chain, putative 0.0601 0.5137 0.7399
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0196 0.0211
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0187 0.0269
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0044 0.0047
Echinococcus granulosus glycine receptor subunit alpha 1 0.0203 0.1646 0.1765
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Echinococcus granulosus alpha tubulin 0.0601 0.5137 0.551
Trypanosoma brucei unspecified product 0.002 0.0044 0.0063
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0416 0.0446
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0203 0.1646 0.1646
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0416 0.0446
Plasmodium falciparum tubulin epsilon chain, putative 0.0433 0.3668 0.5282
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0203 0.1646 0.1765
Brugia malayi hypothetical protein 0.0098 0.0731 0.1053
Echinococcus granulosus beta LACTamase domain containing family member 0.008 0.0571 0.0612
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0723 0.1041
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0044 0.0063
Schistosoma mansoni acetylcholine receptor-related 0.0098 0.0731 0.0784
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0014 0.0015
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0203 0.1646 0.1765
Brugia malayi alpha-tubulin 0.0601 0.5137 0.7399
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0104 0.0784 0.0784
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0043 0.0062
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0203 0.1646 0.1765
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.005 0.031 0.2042
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0241 0.0259
Echinococcus multilocularis tubulin subunit beta 0.0807 0.6944 0.7447
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0187 0.0269
Schistosoma mansoni hypothetical protein 0.0056 0.0364 0.039
Echinococcus granulosus tubulin alpha 3 chain 0.0601 0.5137 0.551
Leishmania major cytochrome p450-like protein 0.0089 0.0651 0.0937
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0203 0.1646 0.1765
Onchocerca volvulus 0.0178 0.1426 0.3391
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.008 0.0571 0.0571
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0196 0.0282
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.021 0.0225
Brugia malayi PXA domain containing protein 0.002 0.0044 0.0063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0098 0.0731 0.1053
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0043 0.0062
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0041 0.0044
Echinococcus multilocularis survival motor neuron protein 1 0.0276 0.2292 0.2459
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Brugia malayi hypothetical protein 0.0098 0.0731 0.1053
Echinococcus granulosus dna polymerase eta 0.002 0.0044 0.0047
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.024 0.0257
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0187 0.0269
Trypanosoma brucei cytochrome P450, putative 0.0089 0.0651 0.0937
Brugia malayi follicle stimulating hormone receptor 0.0489 0.4155 0.5984
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0046 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0723 0.1041
Brugia malayi hypothetical protein 0.0098 0.0731 0.1053
Loa Loa (eye worm) tubulin beta-4 chain 0.0807 0.6944 0.6944
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0188 0.1519 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0187 0.0269
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0511 0.4348 1
Schistosoma mansoni tubulin subunit epsilon 0.0433 0.3668 0.3934
Plasmodium falciparum thioredoxin reductase 0.0105 0.0786 0.1132
Schistosoma mansoni single-minded 0.005 0.0311 0.0334
Mycobacterium tuberculosis Probable lipase LipE 0.008 0.0571 0.1312
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.2252 0.3243
Loa Loa (eye worm) tubulin alpha 2 0.0413 0.3488 0.3488
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0265 0.2193 0.5044
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0203 0.1646 0.237
Entamoeba histolytica hypothetical protein 0.0042 0.024 0.0346
Loa Loa (eye worm) tubulin alpha chain 0.0601 0.5137 0.5137
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0265 0.2193 1
Echinococcus multilocularis tubulin alpha 1C chain 0.0601 0.5137 0.551
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Brugia malayi Tubulin beta-1 chain 0.0807 0.6944 1
Mycobacterium tuberculosis Cell division protein FtsZ 0.0188 0.1519 0.3492
Onchocerca volvulus 0.0056 0.0364 0.0865
Trichomonas vaginalis tubulin, putative 0.0188 0.1519 0.2187
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.005 0.031 0.0713
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0043 0.0062
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0051 0.0318 0.0458
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0187 0.0269
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0196 0.021
Loa Loa (eye worm) tubulin alpha-2 chain 0.0601 0.5137 0.5137
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0435 0.3679 0.3679
Plasmodium falciparum glutathione reductase 0.0105 0.0786 0.1132
Schistosoma mansoni nAChR subunit 0.0098 0.0731 0.0784
Trypanosoma cruzi epsilon tubulin, putative 0.0433 0.3668 0.5282
Brugia malayi Cytochrome P450 family protein 0.0089 0.0651 0.0937
Brugia malayi hypothetical protein 0.0169 0.1351 0.1946
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0104 0.0784 0.1129
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0091 0.0132
Schistosoma mansoni tubulin subunit beta 0.0807 0.6944 0.7447
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Trypanosoma cruzi tubulin delta chain 0.0188 0.1519 0.2187
Leishmania major zeta tubulin, putative 0.0188 0.1519 0.2187
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0041 0.0044
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0044 0.0063
Brugia malayi beta-lactamase family protein 0.008 0.0571 0.0822
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0044 0.0047
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.005 0.031 0.2042
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0203 0.1646 0.1646
Trypanosoma brucei epsilon tubulin 0.0433 0.3668 0.5282
Trypanosoma brucei epsilon tubulin 0.0433 0.3668 0.5282
Loa Loa (eye worm) hypothetical protein 0.0601 0.5137 0.5137
Plasmodium falciparum ataxin-2 like protein, putative 0.0086 0.062 0.0893
Echinococcus multilocularis Tubulin beta 2C chain 0.0807 0.6944 0.7447
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0323 0.27 0.2895
Echinococcus granulosus tubulin alpha chain 0.0601 0.5137 0.551
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0021
Trichomonas vaginalis tubulin beta chain, putative 0.0601 0.5137 0.7399
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0187 0.0269
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0014 0.0021
Echinococcus granulosus glycine receptor subunit beta 0.0203 0.1646 0.1765
Brugia malayi Pre-SET motif family protein 0.0062 0.0416 0.0599
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0196 0.0282
Echinococcus multilocularis tubulin alpha chain 0.0601 0.5137 0.551
Trypanosoma brucei zeta tubulin, putative 0.0188 0.1519 0.2187
Leishmania major beta tubulin 0.0807 0.6944 1
Toxoplasma gondii beta-tubulin, putative 0.0807 0.6944 1
Echinococcus multilocularis tubulin beta 1 chain 0.0807 0.6944 0.7447
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.005 0.031 0.0447
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.005 0.031 0.0713
Brugia malayi excitatory GABA receptor EXP-1A 0.0203 0.1646 0.237
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0104 0.0784 0.1129
Plasmodium vivax tubulin beta chain, putative 0.0807 0.6944 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0265 0.2193 0.5044
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0044 0.0047
Echinococcus granulosus intermediate filament protein 0.0088 0.0639 0.0686
Loa Loa (eye worm) RGS-3 protein 0.002 0.0044 0.0044
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0098 0.0731 0.1053
Loa Loa (eye worm) hypothetical protein 0.0707 0.6069 0.6069
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0203 0.1646 0.1765
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0091 0.0132
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0203 0.1646 0.1765
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.2252 0.3243
Schistosoma mansoni nAChR subunit 0.0203 0.1646 0.1765
Brugia malayi cytochrome P450 0.005 0.031 0.0447
Schistosoma mansoni tubulin subunit delta 0.0188 0.1519 0.1629
Brugia malayi hypothetical protein 0.0178 0.1426 0.2054
Onchocerca volvulus 0.0203 0.1646 0.3913
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0043 0.0062
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0044 0.0047
Mycobacterium ulcerans cell division protein FtsZ 0.0188 0.1519 1
Schistosoma mansoni hypothetical protein 0.005 0.031 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0046 0.005
Schistosoma mansoni regulator of G protein signaling 0.002 0.0044 0.0047
Loa Loa (eye worm) hypothetical protein 0.0086 0.062 0.062
Schistosoma mansoni neurotransmitter gated ion channel 0.0098 0.0731 0.0784
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0038 0.0206 0.0221
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.0103 0.0148
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0044 0.0063
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0571 0.0822
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.0965 0.0965
Trichomonas vaginalis tubulin, putative 0.0245 0.2019 0.2907
Echinococcus multilocularis nAChR subunit 0.0203 0.1646 0.1765
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0105 0.0786 0.1807
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Loa Loa (eye worm) hypothetical protein 0.0178 0.1426 0.1426
Echinococcus multilocularis tubulin epsilon chain 0.0433 0.3668 0.3934
Echinococcus multilocularis Tubulin alpha 1 chain 0.0601 0.5137 0.551
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0203 0.1646 0.237
Trichomonas vaginalis glucosylceramidase, putative 0.0272 0.2252 0.3243
Brugia malayi MH2 domain containing protein 0.0125 0.0965 0.139
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0196 0.0282
Entamoeba histolytica hypothetical protein 0.0104 0.0784 0.1129
Trichomonas vaginalis tubulin gamma chain, putative 0.0433 0.3668 0.5282
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0044 0.0063
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0239 0.196 0.4507
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0168 0.1341 0.1341
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0044 0.0063
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.0571 0.0822
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0203 0.1646 0.237
Onchocerca volvulus 0.008 0.0571 0.1357
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0203 0.1646 0.237
Brugia malayi Pre-SET motif family protein 0.0435 0.3679 0.5299
Entamoeba histolytica acetyltransferase, GNAT family 0.0087 0.0632 0.0911
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1433 0.2063
Brugia malayi Fli-1 protein 0.023 0.1887 0.2718
Toxoplasma gondii alpha tubulin TUBA1 0.0601 0.5137 0.7399
Echinococcus granulosus tubulin epsilon chain 0.0433 0.3668 0.3934
Loa Loa (eye worm) hypothetical protein 0.0098 0.0731 0.0731
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.005 0.031 0.0447
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.021 0.0225
Schistosoma mansoni tubulin subunit alpha 0.0601 0.5137 0.551
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0285 0.0306
Echinococcus multilocularis Tubulin alpha 1 chain 0.0601 0.5137 0.551
Loa Loa (eye worm) hypothetical protein 0.0153 0.1212 0.1212
Leishmania major beta tubulin 0.0807 0.6944 1
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0044
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0416 0.0599
Mycobacterium tuberculosis Probable hydrolase 0.008 0.0571 0.1312
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0272 0.2252 0.3243
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0044 0.0047
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0203 0.1646 0.1646
Leishmania major DNA polymerase kappa, putative 0.002 0.0044 0.0063
Trypanosoma cruzi tubulin gamma chain 0.0433 0.3668 0.5282
Brugia malayi hypoxia-induced factor 1 0.0156 0.1237 0.1781
Plasmodium falciparum alpha tubulin 2 0.0601 0.5137 0.7399
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0046 0.005
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.005 0.031 0.0713
Schistosoma mansoni gabp alpha 0.0076 0.0534 0.0573
Echinococcus granulosus axis inhibition protein axin 0.002 0.0044 0.0047
Schistosoma mansoni alpha-glucosidase 0.0145 0.1136 0.1219
Brugia malayi Cell division protein ftsZ 0.0188 0.1519 0.2187
Mycobacterium leprae cell division protein FtsZ 0.0188 0.1519 0.6418
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0203 0.1646 0.237
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0241 0.0259
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0416 0.0446
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.005 0.031 0.2042
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0203 0.1646 0.237
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0187 0.0269
Plasmodium falciparum tubulin delta chain, putative 0.0188 0.1519 0.2187
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0187 0.1231
Echinococcus multilocularis GA binding protein alpha chain 0.0076 0.0534 0.0573
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0187 0.0269
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0187 0.0201
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0044 0.0063
Trypanosoma brucei beta tubulin 0.0807 0.6944 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.005 0.031 0.0713
Leishmania major hypothetical protein, conserved 0.008 0.0571 0.0822
Echinococcus multilocularis tubulin alpha chain 0.0601 0.5137 0.551
Echinococcus multilocularis beta LACTamase domain containing family member 0.008 0.0571 0.0612
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Brugia malayi Intermediate filament tail domain containing protein 0.0088 0.0639 0.0921
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0203 0.1646 0.1765
Trypanosoma cruzi trypanothione reductase, putative 0.0105 0.0786 0.1132
Loa Loa (eye worm) cytochrome P450 family protein 0.0175 0.1402 0.1402
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0014 0.0015
Trichomonas vaginalis tubulin beta chain, putative 0.0601 0.5137 0.7399
Echinococcus multilocularis 0.005 0.031 0.0333
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.005 0.031 0.0713
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0187 0.0269
Loa Loa (eye worm) hypothetical protein 0.0137 0.1074 0.1074
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.024 0.0257
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0203 0.1646 0.237
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0433 0.3668 0.5282
Schistosoma mansoni alpha tubulin 0.0601 0.5137 0.551
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0044 0.0044
Echinococcus multilocularis dna polymerase kappa 0.002 0.0044 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0723 0.1041
Plasmodium vivax glutathione reductase, putative 0.0105 0.0786 0.1132
Loa Loa (eye worm) hypothetical protein 0.0086 0.0625 0.0625
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0187 0.0269
Schistosoma mansoni axis inhibition protein axin 0.002 0.0044 0.0047
Loa Loa (eye worm) hypothetical protein 0.0329 0.275 0.275
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.005 0.031 0.0713
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Brugia malayi Tubulin alpha chain 0.0188 0.1519 0.2187
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0203 0.1646 0.1765
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0187 0.5
Brugia malayi Thioredoxin reductase 0.0105 0.0786 0.1132
Echinococcus multilocularis glycine receptor subunit beta 0.0203 0.1646 0.1765
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0203 0.1646 0.1765
Trichomonas vaginalis tubulin beta chain, putative 0.0601 0.5137 0.7399
Loa Loa (eye worm) beta-tubulin 0.0807 0.6944 0.6944
Brugia malayi beta-lactamase 0.008 0.0571 0.0822
Leishmania major cytochrome p450-like protein 0.005 0.031 0.0447
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0044 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.1433 0.2063
Brugia malayi Cytochrome P450 family protein 0.0089 0.0651 0.0937
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0044 0.0063
Schistosoma mansoni tubulin subunit alpha 0.0601 0.5137 0.551
Treponema pallidum NADH oxidase 0.0036 0.0187 0.0976
Onchocerca volvulus 0.0203 0.1646 0.3913
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0416 0.0446
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0285 0.041
Schistosoma mansoni ap endonuclease 0.002 0.0043 0.0046
Loa Loa (eye worm) hypothetical protein 0.0104 0.0784 0.0784
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0044 0.0063
Schistosoma mansoni intermediate filament proteins 0.0088 0.0639 0.0686
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0044 0.0047
Plasmodium vivax tubulin epsilon chain, putative 0.0433 0.3668 0.5282
Echinococcus multilocularis nAChR subunit 0.0104 0.0784 0.0841
Mycobacterium ulcerans hypothetical protein 0.008 0.0571 0.3757
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0044 0.0063
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0044 0.0047
Echinococcus multilocularis tubulin alpha chain 0.0601 0.5137 0.551
Brugia malayi hypothetical protein 0.0086 0.062 0.0893
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0044 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0723 0.1041
Trichomonas vaginalis tubulin gamma chain, putative 0.0433 0.3668 0.5282
Onchocerca volvulus 0.008 0.0571 0.1357
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0044 0.0288
Echinococcus granulosus Tubulin alpha 1 chain 0.0601 0.5137 0.551
Brugia malayi beta-tubulin, identical 0.0807 0.6944 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0043 0.0062
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0043 0.0043
Trichomonas vaginalis esterase, putative 0.008 0.0571 0.0822
Trichomonas vaginalis tubulin, putative 0.0245 0.2019 0.2907
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0044 0.0047
Echinococcus granulosus cytochrome P450 2K1 0.005 0.031 0.0333
Onchocerca volvulus 0.0088 0.0639 0.152
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.005 0.031 0.0713
Loa Loa (eye worm) hypothetical protein 0.008 0.0571 0.0571
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0187 0.0269
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0203 0.1646 0.1765
Leishmania major beta tubulin 0.0807 0.6944 1
Plasmodium falciparum thioredoxin reductase 0.0036 0.0187 0.0269
Onchocerca volvulus 0.0062 0.0416 0.0989
Trichomonas vaginalis tubulin epsilon chain, putative 0.0188 0.1519 0.2187
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0203 0.1646 0.237
Trypanosoma cruzi epsilon tubulin, putative 0.0433 0.3668 0.5282
Echinococcus granulosus single minded 2 0.0041 0.0228 0.0244
Schistosoma mansoni alpha tubulin 0.0601 0.5137 0.551
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0203 0.1646 0.1765
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0245 0.2019 0.2907
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Schistosoma mansoni acetylcholine receptor subunit beta 0.0098 0.0731 0.0784
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0196 0.0282
Trichomonas vaginalis tubulin alpha chain, putative 0.0245 0.2019 0.2907
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0044 0.0047
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0807 0.6944 0.7447
Loa Loa (eye worm) hypothetical protein 0.0062 0.0416 0.0416
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.005 0.031 0.0713
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0044
Echinococcus multilocularis tubulin alpha 3 chain 0.0601 0.5137 0.551
Leishmania major hypothetical protein, conserved 0.0086 0.062 0.0893
Toxoplasma gondii thioredoxin reductase 0.0105 0.0786 0.1132
Giardia lamblia Beta tubulin 0.0807 0.6944 1
Loa Loa (eye worm) GABA receptor subunit 0.0104 0.0784 0.0784
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0044 0.0101
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0044
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0044 0.0063
Trypanosoma brucei beta tubulin 0.0807 0.6944 1
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0196 0.0282
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0196 0.0282
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.005 0.031 0.2042
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0043 0.0046
Echinococcus multilocularis glycine receptor subunit beta 0.0203 0.1646 0.1765
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0265 0.2193 0.5044
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.005 0.031 0.0713
Onchocerca volvulus 0.0104 0.0784 0.1865
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0041 0.0044
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0188 0.1519 0.2187
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0044 0.0047
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0187 0.0269
Echinococcus multilocularis tubulin alpha chain 0.0601 0.5137 0.551
Loa Loa (eye worm) fli-1 protein 0.023 0.1887 0.1887
Schistosoma mansoni tubulin subunit beta 0.0807 0.6944 0.7447
Echinococcus granulosus dna polymerase kappa 0.002 0.0044 0.0047
Leishmania major beta tubulin 0.0807 0.6944 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0784 0.0784
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0203 0.1646 0.237
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0044 0.0063
Leishmania major alpha tubulin 0.0601 0.5137 0.7399
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0095 0.0702 0.1011
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.015 0.0217
Loa Loa (eye worm) thioredoxin reductase 0.0105 0.0786 0.0786
Echinococcus granulosus tubulin subunit TubB 0.0601 0.5137 0.551
Mycobacterium tuberculosis Probable lipase LipD 0.008 0.0571 0.1312
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0187 0.0269
Schistosoma mansoni ap endonuclease 0.002 0.0043 0.0046
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0239 0.196 0.4507
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0041 0.0059
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.005 0.031 0.0447
Trichomonas vaginalis tubulin epsilon chain, putative 0.0807 0.6944 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.1646 0.1646
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0364 0.0524
Echinococcus multilocularis expressed protein 0.0387 0.3259 0.3495
Onchocerca volvulus 0.0203 0.1646 0.3913
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0044 0.0063
Entamoeba histolytica hypothetical protein 0.002 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0065 0.0438 0.0438

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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