Detailed information for compound 1141658

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 300.281 | Formula: C17H13FO4
  • H donors: 0 H acceptors: 1 LogP: 3.64 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(OC)cc2c1C(=O)/C(=C/c1ccc(cc1)F)/O2
  • InChi: 1S/C17H13FO4/c1-20-12-8-13(21-2)16-14(9-12)22-15(17(16)19)7-10-3-5-11(18)6-4-10/h3-9H,1-2H3/b15-7-
  • InChiKey: DEFCYYCAIYFANA-CHHVJCJISA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis smad 0.0028 0.0135 0.0188
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.001 0.0001 0.0027
Loa Loa (eye worm) hypothetical protein 0.014 0.1006 0.2735
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0414 0.3116 0.8211
Schistosoma mansoni tsg101-related 0.0133 0.0947 0.1322
Brugia malayi hypothetical protein 0.001 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0149 0.0406
Echinococcus granulosus muscleblind protein 0.0487 0.3679 0.5139
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0119 1
Echinococcus granulosus axis inhibition protein axin 0.0011 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.014 0.1006 0.2735
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0111 0.0685
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Echinococcus multilocularis Smad4 0.0028 0.0135 0.0188
Echinococcus granulosus regulator of G protein signaling 3 0.0011 0.0007 0.001
Schistosoma mansoni regulator of G protein signaling 0.0031 0.0164 0.0229
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.001 0.0001 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0547 0.0765
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0092 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0309 0.0431
Schistosoma mansoni tsg101-related 0.0108 0.0759 0.106
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0328 0.0459
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.004 0.0056
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0012 0.0016 0.0043
Schistosoma mansoni tsg101-related 0.0133 0.0947 0.1322
Giardia lamblia Kinase, PLK 0.0217 0.1597 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0033
Schistosoma mansoni zinc finger protein 0.0027 0.0129 0.018
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0023 0.0097 0.0264
Brugia malayi mbt repeat family protein 0.0046 0.0279 0.0758
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0547 0.0765
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.001 0.0001 0.0002
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.001 0.0001 0.0002
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.001 0.0001 0.0002
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Echinococcus granulosus expressed protein 0.0038 0.0218 0.0304
Onchocerca volvulus 0.001 0.0002 0.0003
Trichomonas vaginalis rotamase, putative 0.0038 0.0218 0.057
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0309 0.1926
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0002 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0028 0.0135 0.0366
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0317 0.7543
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0033
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0309 0.081
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0018 0.0064 0.0164
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.001 0.0001 0.0002
Schistosoma mansoni bromodomain containing protein 0.0012 0.0015 0.002
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0309 0.1926
Toxoplasma gondii histone lysine methyltransferase SET1 0.0133 0.0952 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0012 0.0016 0.0022
Schistosoma mansoni lamin 0.0029 0.0149 0.0208
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0015 0.0034 0.0048
Loa Loa (eye worm) RasGEF domain-containing protein 0.0017 0.0052 0.0142
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0088 0.0603 0.0842
Entamoeba histolytica type A flavoprotein, putative 0.0018 0.0064 0.039
Brugia malayi hypothetical protein 0.0012 0.0012 0.0033
Brugia malayi PXA domain containing protein 0.0011 0.0007 0.0019
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.004 0.0056
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0019
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.001 0.0001 0.0004
Echinococcus granulosus cpg binding protein 0.0071 0.0474 0.0661
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0032 0.0044
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.001 0.0001 0.0002
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0088 0.0603 0.1585
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Echinococcus multilocularis regulator of G protein signaling 7 0.0031 0.0164 0.0229
Echinococcus multilocularis dnaJ subfamily B 0.0937 0.7159 1
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0092 0.0129
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0137 0.0982 0.1372
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0025 0.0035
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0004
Toxoplasma gondii metallo-beta-lactamase domain-containing protein 0.0018 0.0064 0.0668
Brugia malayi hypothetical protein 0.002 0.0079 0.0216
Brugia malayi nuclear receptor NHR-88 0.001 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0095
Schistosoma mansoni rotamase 0.0038 0.0218 0.0304
Brugia malayi ecdysteroid receptor 0.0022 0.0092 0.0251
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0092 0.0251
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.005 0.0069
Schistosoma mansoni DNA helicase recq1 0.0023 0.0097 0.0136
Echinococcus multilocularis axis inhibition protein axin 0.0011 0.0007 0.001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.001 0.0001 0.0002
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0018 0.0064 0.039
Loa Loa (eye worm) hypothetical protein 0.0487 0.3679 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.042 0.0587
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0086
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.001 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0018 0.0064 0.0089
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0002 0.0007
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.001 0.0001 0.0053
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.001 0.0001 0.0002
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0015 0.0034 0.0086
Brugia malayi Regulator of G protein signaling domain containing protein 0.0011 0.0007 0.0019
Schistosoma mansoni nuclear hormone receptor 0.001 0.0002 0.0003
Echinococcus granulosus mothers against decapentaplegic 6 0.0012 0.0017 0.0024
Giardia lamblia Metallo-beta-lactamase superfamily protein 0.0018 0.0064 0.039
Loa Loa (eye worm) acetyltransferase 0.0168 0.1222 0.3321
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0215 0.1586 0.1532
Onchocerca volvulus 0.0064 0.042 0.1103
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.001 0.0001 0.0002
Loa Loa (eye worm) hydroxyacylglutathione hydrolase 0.0018 0.0064 0.0173
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0018 0.0064 0.0089
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0309 0.1933
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0092 0.0251
Loa Loa (eye worm) nuclear factor I 0.0015 0.004 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0092 0.0251
Brugia malayi DIX domain containing protein 0.0023 0.0097 0.0264
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0309 0.1926
Brugia malayi metallo-beta-lactamase superfamily protein 0.0018 0.0064 0.0173
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0097 0.0253
Plasmodium vivax unspecified product 0.0018 0.0064 0.151
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.001 0.0001 0.0002
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0317 0.3329
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Brugia malayi metallo-beta-lactamase superfamily protein 0.0018 0.0064 0.0173
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Onchocerca volvulus 0.002 0.0079 0.0205
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0092 0.0251
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.001 0.0001 0.0002
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0002 0.0007
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0233 0.1452
Echinococcus granulosus dnaJ subfamily B 0.0937 0.7159 1
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Schistosoma mansoni microtubule-associated protein tau 0.079 0.6025 0.8416
Echinococcus multilocularis zinc phosphodiesterase 0.0018 0.0064 0.0089
Echinococcus multilocularis cpg binding protein 0.0071 0.0474 0.0661
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0012 0.0121
Echinococcus multilocularis expressed protein 0.001 0.0001 0.0002
Echinococcus granulosus son of sevenless 1 0.0015 0.0034 0.0048
Trypanosoma cruzi ISWI complex protein 0.0015 0.0037 0.022
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0092 0.0129
Schistosoma mansoni axis inhibition protein axin 0.0011 0.0007 0.001
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.0097 0.364
Echinococcus multilocularis zinc finger protein 0.0027 0.0129 0.018
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0088 0.0603 0.0842
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0182 0.1328 0.1855
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0092 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0037 0.0095
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.001 0.0001 0.0002
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Trypanosoma brucei hydroxyacylglutathione hydrolase, putative 0.0018 0.0064 0.039
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0016 0.0022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0092 0.0129
Schistosoma mansoni hypothetical protein 0.0281 0.2091 0.292
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0095
Loa Loa (eye worm) MH2 domain-containing protein 0.0404 0.3039 0.8261
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0309 0.3243
Onchocerca volvulus 0.0018 0.0064 0.0164
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0093
Loa Loa (eye worm) hypothetical protein 0.0414 0.3116 0.847
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.001 0.0001 0.0002
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0088 0.0603 0.377
Brugia malayi MH2 domain containing protein 0.0028 0.0135 0.0366
Schistosoma mansoni thyroid hormone receptor 0.0159 0.1152 0.161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0092 0.0251
Echinococcus granulosus smad 0.0028 0.0135 0.0188
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0088 0.0603 0.377
Leishmania major cleavage and polyadenylation specificity factor, putative 0.0018 0.0064 0.0398
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0182 0.1328 0.1855
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0111 0.4134
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0097 0.0136
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.001 0.0001 0.0002
Echinococcus granulosus axis inhibition protein axin 0.0011 0.0007 0.001
Onchocerca volvulus Hydroxyacylglutathione hydrolase, mitochondrial homolog 0.0018 0.0064 0.0164
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0092 0.0129
Schistosoma mansoni hypothetical protein 0.0018 0.0064 0.0089
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0119 1
Brugia malayi MH1 domain containing protein 0.0015 0.004 0.0108
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0111 0.263
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0002 0.0003
Echinococcus multilocularis muscleblind protein 1 0.0487 0.3679 0.5139
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0075
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0018 0.0064 0.039
Schistosoma mansoni nuclear receptor 0.001 0.0002 0.0003
Brugia malayi ethe1-prov protein 0.0018 0.0064 0.0173
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0268 0.1669
Schistosoma mansoni peptidase 0.0011 0.001 0.0014
Leishmania major metallo-beta-lactamase family-like protein 0.0018 0.0064 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0015
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0012 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0095
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0092 0.0251
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0018 0.0064 0.039
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Echinococcus granulosus ETHE1 protein 0.0018 0.0064 0.0089
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0051
Entamoeba histolytica hypothetical protein 0.0015 0.0034 0.0206
Loa Loa (eye worm) hypothetical protein 0.0053 0.0328 0.0892
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0002 0.0007
Brugia malayi MH1 domain containing protein 0.0028 0.0135 0.0366
Schistosoma mansoni Smad4 0.0028 0.0135 0.0188
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0015 0.0034 0.0048
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.001 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0388 0.292 0.4079
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0012 0.0012 0.0267
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Echinococcus multilocularis thyroid hormone receptor alpha 0.0159 0.1152 0.161
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0092 0.0129
Loa Loa (eye worm) metallo-beta-lactamase superfamily protein 0.0018 0.0064 0.0173
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0012 0.0012 0.0067
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.002 0.0079 0.0216
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0011 0.0008 0.0186
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0097 0.1024
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0011 0.0007 0.001
Schistosoma mansoni axis inhibition protein axin 0.0011 0.0007 0.001
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0217 0.1597 0.434
Echinococcus multilocularis mothers against decapentaplegic 6 0.0012 0.0017 0.0024
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0018 0.0064 0.0089
Echinococcus multilocularis geminin 0.0388 0.292 0.4079
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0002 0.0003
Echinococcus multilocularis regulator of G protein signaling 7 0.0031 0.0164 0.0229
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Echinococcus granulosus segment polarity protein dishevelled 0.0023 0.0097 0.0136
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0317 0.0443
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0268 0.1669
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0753 0.1981
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0092 0.0251
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0092 0.0129
Echinococcus multilocularis Regulator of G protein signaling 20 0.0011 0.0007 0.001
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.001 0.0001 0.0004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0391 0.0546
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0012 0.0016
Brugia malayi RasGEF domain containing protein 0.0015 0.0034 0.0093
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0233 0.0611
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.012 0.0167
Plasmodium falciparum cytosolic glyoxalase II 0.0018 0.0064 0.2377
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0279 0.039
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0092 0.0129
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0066 0.0093
Schistosoma mansoni zinc finger protein 0.0015 0.0037 0.0051
Brugia malayi hypothetical protein 0.014 0.1006 0.2735
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.1305 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.1597 0.4206
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0097 0.0265
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0037 0.0095
Echinococcus granulosus regulator of G protein signaling 7 0.0031 0.0164 0.0229
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.001 0.0001 0.0002
Onchocerca volvulus 0.0029 0.0149 0.039
Loa Loa (eye worm) RasGEF domain-containing protein 0.0015 0.0034 0.0093
Loa Loa (eye worm) GoLoco domain-containing protein family protein 0.0028 0.0136 0.0368
Echinococcus granulosus hydroxyacylglutathione hydrolase 0.0018 0.0064 0.0089
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0092 0.0251
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0038 0.0218 0.0592
Loa Loa (eye worm) hypothetical protein 0.0487 0.3679 1
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.011 0.0298
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0307 0.0429
Schistosoma mansoni inositol monophosphatase 0.004 0.0233 0.0326
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0011 0.0007 0.001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.001 0.0001 0.0002
Plasmodium falciparum ubiquitin specific protease, putative 0.001 0.0001 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0095
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0037 0.0095
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0092 0.0251
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0016 0.0022
Brugia malayi hypothetical protein 0.0011 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0251
Echinococcus multilocularis muscleblind protein 0.0487 0.3679 0.5139
Brugia malayi hypothetical protein 0.0018 0.0064 0.0173
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0031 0.0164 0.0446
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.1597 0.4206
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0449 0.3388 0.3346
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0002 0.0003
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0088 0.0603 0.0842
Onchocerca volvulus 0.0011 0.0008 0.0018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0066 0.0093
Schistosoma mansoni lamin 0.0029 0.0149 0.0208
Schistosoma mansoni Smad4 0.0012 0.0017 0.0024
Echinococcus granulosus TGF beta signal transducer SmadC 0.0028 0.0135 0.0188
Brugia malayi RasGEF domain containing protein 0.0015 0.0034 0.0093
Entamoeba histolytica hypothetical protein 0.0027 0.0128 0.0793
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0097 0.0265
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0119 0.283
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0002 0.0003
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0547 0.0765
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0088 0.0603 0.377
Brugia malayi Nuclear hormone receptor E75 0.001 0.0002 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0064 0.0164
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.005 0.0069
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0279 0.0758
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.001 0.0001 0.0002
Brugia malayi ubiquitin specific protease 14 0.001 0.0001 0.0004
Schistosoma mansoni smad1 5 8 and 0.0028 0.0135 0.0188
Brugia malayi nuclear hormone receptor 0.001 0.0002 0.0007
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0002 0.0003
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0233 0.0326
Echinococcus granulosus zinc phosphodiesterase 0.0018 0.0064 0.0089
Schistosoma mansoni hypothetical protein 0.0018 0.0064 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0064 0.0164
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0012 0.0016 0.0043
Brugia malayi Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. 0.0018 0.0064 0.0173
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0033
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.001 0.0001 0.0027
Trichomonas vaginalis apoptosis inducing factor, putative 0.0018 0.0064 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0064 0.0164
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0037 0.0095
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0018 0.0064 0.0089
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0119 0.1251
Trichomonas vaginalis ras GTP exchange factor, putative 0.0015 0.0034 0.0086
Schistosoma mansoni regulator of G protein signaling 0.0011 0.0007 0.001
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0111 0.1163
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0016 0.0022
Giardia lamblia Sgs1 DNA helicase, putative 0.0023 0.0097 0.0602
Brugia malayi MH2 domain containing protein 0.0028 0.0135 0.0366
Onchocerca volvulus 0.0029 0.0149 0.039
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0023 0.0097 0.0136
Schistosoma mansoni calpain-7 (C02 family) 0.001 0.0001 0.0002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Loa Loa (eye worm) RecQ helicase 0.0023 0.0097 0.0265
Schistosoma mansoni nuclear hormone receptor 0.001 0.0002 0.0003
Mycobacterium tuberculosis Possible hydrolase 0.0018 0.0064 0.0023
Mycobacterium tuberculosis Beta lactamase like protein 0.0018 0.0064 0.0023
Mycobacterium tuberculosis Conserved protein 0.0018 0.0064 0.0023
Schistosoma mansoni ras GTP exchange factor 0.0015 0.0034 0.0048
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0233 1
Trichomonas vaginalis beta lactamase domain, putative 0.0018 0.0064 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.1597 0.4206
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0128 0.0334
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0092 0.0129
Loa Loa (eye worm) hypothetical protein 0.0346 0.2596 0.7055
Echinococcus granulosus raf serine:threonine protein kinase 0.0099 0.0685 0.0957
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0088 0.0603 0.377
Entamoeba histolytica hypothetical protein 0.0011 0.0007 0.0035
Brugia malayi Raf kinase 0.0099 0.0685 0.1862
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.001 0.0001 0.0002
Trichomonas vaginalis hypothetical protein 0.0078 0.0521 0.1371
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.001 0.0001 0.0002
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.001 0.0001 0.0053
Schistosoma mansoni hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) 0.0018 0.0064 0.0089
Trypanosoma cruzi hypothetical protein 0.0015 0.0034 0.0206
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.004 0.0252
Loa Loa (eye worm) PXA domain-containing protein 0.0011 0.0007 0.0019
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0023 0.0097 0.0136
Echinococcus granulosus histone acetyltransferase KAT2B 0.0161 0.1168 0.1632
Echinococcus granulosus Protein son of sevenless 0.0015 0.0034 0.0048
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.001 0.0001 0.0027
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0097 0.0253
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0004
Schistosoma mansoni dishevelled 0.0023 0.0097 0.0136
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0013 0.0025 0.0266
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0015 0.0034 0.0048
Trichomonas vaginalis A-type flavoprotein 0.0018 0.0064 0.0164
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.001 0.0001 0.0002
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0097 0.061
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.1597 0.4206
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0092 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0095
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0309 0.081
Onchocerca volvulus Huntingtin homolog 0.014 0.1006 0.2649
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.002 0.0079 0.0111
Entamoeba histolytica hypothetical protein 0.0011 0.0007 0.0035
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.1305 1 1
Trichomonas vaginalis beta lactamase domain, putative 0.0018 0.0064 0.0164
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0097 0.0136
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.001 0.0001 0.0002
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0012 0.0017 0.0041
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0019
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0031
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0233 0.0171
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0002 0.0003
Echinococcus granulosus segment polarity protein dishevelled 0.0023 0.0097 0.0136
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.001 0.0001 0.0002
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0328 0.0892
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0023 0.0097 0.0136
Brugia malayi MH2 domain containing protein 0.0404 0.3039 0.8261
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0066 0.0093
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.005 0.0069
Schistosoma mansoni z-protein (S1r protein) 0.0031 0.0164 0.0229
Loa Loa (eye worm) RGS-3 protein 0.0011 0.0007 0.0019
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0088 0.0603 0.1585
Plasmodium vivax hypothetical protein, conserved 0.001 0.0001 0.0027
Brugia malayi Smad1 0.0028 0.0135 0.0366
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.0819
Mycobacterium tuberculosis Conserved protein 0.0018 0.0064 0.0023
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.001 0.0001 0.0002
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0002 0.0003
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0037 0.0211 0.1312
Echinococcus granulosus mothers against decapentaplegic 2 0.0012 0.0017 0.0024
Echinococcus multilocularis musashi 0.0029 0.0149 0.0208
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0233 0.1452
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0173
Schistosoma mansoni bromodomain containing protein 0.0069 0.0456 0.0637
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.004 0.0056
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.001 0.0001 0.0002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0251
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Trypanosoma cruzi glyoxalase II 0.0018 0.0064 0.039
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0128 0.0793
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Schistosoma mansoni hypothetical protein 0.0388 0.292 0.4079
Schistosoma mansoni Smad4 0.0012 0.0017 0.0024
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0018 0.0064 0.039
Echinococcus granulosus lamin dm0 0.0029 0.0149 0.0208
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Echinococcus granulosus Regulator of G protein signaling 20 0.0011 0.0007 0.001
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0233 0.2449
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0002 0.0003
Echinococcus multilocularis regulator of G protein signaling 0.0011 0.0007 0.001
Echinococcus multilocularis microtubule associated protein 2 0.079 0.6025 0.8416
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.001 0.0001 0.0002
Schistosoma mansoni zinc phosphodiesterase 0.0018 0.0064 0.0089
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0309 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0603 0.1585
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0092 0.0129
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0023 0.0097 0.364
Schistosoma mansoni nuclear receptor 0.001 0.0002 0.0003
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.001 0.0001 0.0015
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0037 0.0211 0.1312
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0309 0.1933
Loa Loa (eye worm) hypothetical protein 0.0044 0.0258 0.0702
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0032 0.0044
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0008 0.0042
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0191 0.0267
Echinococcus granulosus regulator of G protein signaling 3 0.0011 0.0007 0.001
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0002 0.0007
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0168 0.1222 0.1707
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0328 0.0459
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0142 0.1018 0.1422
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0007 0.0009
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0217 0.1597 0.2231
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0309 0.1926
Onchocerca volvulus Putative hydrolase PNKD 0.0018 0.0064 0.0164
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Schistosoma mansoni hypothetical protein 0.0137 0.0982 0.1372
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0108 0.0759 0.4749
Trichomonas vaginalis set domain proteins, putative 0.0502 0.3795 1
Brugia malayi Nuclear hormone receptor E75 0.001 0.0002 0.0007
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0449 0.3388 0.3361
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Echinococcus multilocularis raf serine:threonine protein kinase 0.0099 0.0685 0.0957
Trichomonas vaginalis helicase, putative 0.0015 0.0037 0.0095
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0092 0.0251
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0119 0.4447
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.001 0.0001 0.0002
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0097 0.0602
Loa Loa (eye worm) CXXC zinc finger family protein 0.0066 0.043 0.1169
Trypanosoma cruzi polo-like protein kinase, putative 0.0217 0.1597 1
Echinococcus granulosus ubiquitin specific protease 41 0.0088 0.0603 0.0842
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0015
Schistosoma mansoni smad1 5 8 and 0.0028 0.0135 0.0188
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0309 0.081
Trypanosoma brucei glyoxalase II 0.0018 0.0064 0.039
Echinococcus multilocularis expressed protein 0.0038 0.0218 0.0304
Echinococcus granulosus mothers against decapentaplegic 5 0.0028 0.0135 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.1597 0.2231
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0233 0.1452
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0173
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0015 0.0034 0.0048
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0081 0.0547 0.1488
Loa Loa (eye worm) DR-78 0.001 0.0002 0.0007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0233 0.0611
Echinococcus multilocularis ubiquitin specific protease 41 0.0088 0.0603 0.0842
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0088 0.0603 0.3775
Trypanosoma cruzi polo-like protein kinase, putative 0.0217 0.1597 1
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0018 0.0064 0.0089
Schistosoma mansoni cpg binding protein 0.0071 0.0474 0.0661
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0019
Brugia malayi Bromodomain containing protein 0.008 0.0543 0.1477
Echinococcus multilocularis segment polarity protein dishevelled 0.0023 0.0097 0.0136
Onchocerca volvulus Serine\/threonine kinase homolog 0.0217 0.1597 0.4206
Trypanosoma brucei polo-like protein kinase 0.0217 0.1597 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Schistosoma mansoni dep domain containing protein 0.002 0.0079 0.0111
Echinococcus multilocularis lamin 0.0029 0.0149 0.0208
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0011 0.0007 0.001
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0014 0.0029 0.004
Onchocerca volvulus Huntingtin homolog 0.014 0.1006 0.2649
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0093
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0217 0.1597 0.2231
Echinococcus granulosus zinc finger protein 0.0027 0.0129 0.018
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0092 0.0129
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0173
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0201 0.0161
Toxoplasma gondii ubiquitin-specific protease USP4 0.001 0.0001 0.0015
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Echinococcus granulosus Smad4 0.0028 0.0135 0.0188
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0038 0.0218 0.0592
Echinococcus granulosus G protein signaling modulator 2 0.0028 0.0136 0.0189
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0004
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0076 0.0208
Echinococcus multilocularis G protein signaling modulator 2 0.0028 0.0136 0.0189
Schistosoma mansoni kinase 0.011 0.0775 0.1083
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0092 0.0251
Loa Loa (eye worm) DIX domain-containing protein 0.0023 0.0097 0.0264
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0012 0.0033
Loa Loa (eye worm) MH1 domain-containing protein 0.0028 0.0135 0.0366
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.004 0.0056
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0004
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0064 0.0023
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.001 0.0001 0.0002
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.001 0.0001 0.0002
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0097 0.0265
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Brugia malayi conserved hypotetical protein 0.001 0.0002 0.0007
Trypanosoma cruzi glyoxalase II 0.0018 0.0064 0.039
Brugia malayi hypothetical protein 0.0011 0.0007 0.0019
Schistosoma mansoni hypothetical protein 0.002 0.0076 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0092 0.0251
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0044 0.0119
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0092 0.0129
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0191 0.0267
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0251
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0119 0.0056
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0092 0.0129
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0307 0.0835
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.001 0.0001 0.0002
Schistosoma mansoni coup transcription factor 0.0022 0.0092 0.0129
Entamoeba histolytica hypothetical protein 0.0027 0.0128 0.0793
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0008 0.0085
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0037 0.0211 0.1312
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0279 0.039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0317 0.0831
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0092 0.0251
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0149 0.0406
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0119 0.1251
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0307 0.0429
Loa Loa (eye worm) hydroxyacylglutathione hydrolase cytoplasmic 0.0018 0.0064 0.0173
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0088 0.0603 0.0842
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0092 0.0251
Echinococcus granulosus lamin 0.0029 0.0149 0.0208
Onchocerca volvulus 0.0018 0.0064 0.0164
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0002 0.0003
Brugia malayi RasGEF domain containing protein 0.0017 0.0052 0.0142
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0119 0.0745
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0309 0.0431
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0012 0.0017
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0317 0.0831
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.0013 0.0018
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0309 0.1926
Toxoplasma gondii hypothetical protein 0.002 0.0079 0.0834
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0012 0.0067
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0092 0.0129
Brugia malayi hypothetical protein 0.0346 0.2596 0.7055
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.001 0.0001 0.0002
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.001 0.0001 0.0002
Trichomonas vaginalis ras GTP exchange factor, putative 0.0015 0.0034 0.0086
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0028 0.0135 0.0188
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.005 0.0069
Toxoplasma gondii peptidylprolyl isomerase 0.0037 0.0211 0.2214
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.001 0.0001 0.0002
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0092 0.0129
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0268 1
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0128 0.0334
Onchocerca volvulus 0.0091 0.0622 0.1636
Echinococcus granulosus ras GTP exchange factor 0.0015 0.0034 0.0048
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0002
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0092 0.0129
Toxoplasma gondii hypothetical protein 0.001 0.0001 0.0015
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0012 0.0012 0.0126
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0301
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.004 0.011
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0023 0.0097 0.0265
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0265
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0012 0.0033
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0097 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0075
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.001 0.0001 0.0002
Echinococcus granulosus geminin 0.0388 0.292 0.4079
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.001 0.0001 0.0053
Echinococcus multilocularis regulator of G protein signaling 3 0.0011 0.0007 0.001
Trypanosoma brucei ISWI complex protein 0.0015 0.0037 0.022
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0309 0.1926
Schistosoma mansoni smad 0.0028 0.0135 0.0188
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0051 0.0316 0.1969
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0251
Trichomonas vaginalis beta lactamase domain, putative 0.0018 0.0064 0.0164
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.004 0.0954
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.001 0.0001 0.0002
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0092 0.0129
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0119 0.0737
Loa Loa (eye worm) MH1 domain-containing protein 0.0012 0.0017 0.0046
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.001 0.0001 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0092 0.0251
Schistosoma mansoni cpg binding protein 0.0071 0.0474 0.0661
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0037 0.0095
Plasmodium falciparum ubiquitin specific protease, putative 0.001 0.0001 0.0053
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0279 0.039
Loa Loa (eye worm) hypothetical protein 0.0091 0.0622 0.1691
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.001 0.0001 0.0002
Wolbachia endosymbiont of Brugia malayi metallo-beta-lactamase superfamily hydrolase 0.0018 0.0064 0.2334
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0092 0.0129
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.001 0.0001 0.0002
Echinococcus granulosus bloom syndrome protein 0.0023 0.0097 0.0136
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0012 0.0075
Loa Loa (eye worm) hypothetical protein 0.0028 0.0136 0.0368
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0111 0.0685
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0233 0.0611
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0064 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0015
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0119 0.484
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0429 0.0599
Leishmania major hypothetical protein, conserved 0.0024 0.0111 0.0693
Trypanosoma cruzi ISWI complex protein 0.0015 0.0037 0.022
Onchocerca volvulus 0.0502 0.3795 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0012 0.0017
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0092 0.0129
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Brugia malayi nuclear hormone receptor 0.0022 0.0092 0.0251
Entamoeba histolytica alkyl sulfatase, putative 0.0018 0.0064 0.039
Echinococcus granulosus beta-adrenergic receptor kinase 0.0012 0.0016 0.0022
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.001 0.0001 0.0002
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0328 0.0459
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0019
Brugia malayi GoLoco motif family protein 0.0028 0.0136 0.0368
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0251
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0064 0.0164
Trypanosoma cruzi hypothetical protein 0.0015 0.0034 0.0206
Brugia malayi nuclear receptor NHR-67 0.001 0.0002 0.0007
Plasmodium vivax SET domain protein, putative 0.0064 0.042 1
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0002 0.0007
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0279 0.0731
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0092 0.0129
Onchocerca volvulus 0.0046 0.0279 0.0731
Brugia malayi N-terminal motif family protein 0.0015 0.0034 0.0093
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0088 0.0603 0.0842
Echinococcus multilocularis hydroxyacylglutathione hydrolase 0.0018 0.0064 0.0089
Brugia malayi ecdysone receptor 0.001 0.0002 0.0007
Toxoplasma gondii hydroxyacylglutathione hydrolase 0.0018 0.0064 0.0668
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.004 0.1506
Brugia malayi Pre-SET motif family protein 0.0441 0.3326 0.904
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Loa Loa (eye worm) RasGEF domain-containing protein 0.0015 0.0034 0.0093
Schistosoma mansoni calpain-7 (C02 family) 0.001 0.0001 0.0002
Brugia malayi PHD-finger family protein 0.0032 0.0169 0.0459
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Trichomonas vaginalis beta lactamase domain, putative 0.0018 0.0064 0.0164
Brugia malayi isocitrate dehydrogenase 0.0015 0.004 0.011
Brugia malayi MH2 domain containing protein 0.0012 0.0017 0.0046
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0011 0.0007 0.001
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.001 0.0001 0.0002
Echinococcus multilocularis regulator of G protein signaling 3 0.0011 0.0007 0.001
Brugia malayi serine/threonine-protein kinase plk-2 0.0217 0.1597 0.434
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0119 0.0056
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Loa Loa (eye worm) histone methyltransferase 0.0023 0.0097 0.0264
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Entamoeba histolytica hypothetical protein 0.0025 0.0119 0.0737
Loa Loa (eye worm) hypothetical protein 0.0031 0.0164 0.0446
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0307 0.0429
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0051 0.0316 0.1969
Loa Loa (eye worm) MH2 domain-containing protein 0.0012 0.0017 0.0046
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0317 0.3329
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0011 0.0007 0.001
Trypanosoma brucei cleavage and polyadenylation specificity factor subunit, putative 0.0018 0.0064 0.039
Brugia malayi regulator of G-protein signaling egl-10 0.0031 0.0164 0.0446
Brugia malayi nuclear receptor RXR 0.001 0.0002 0.0007
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0137 0.0982 0.1372
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0012 0.0033
Echinococcus granulosus ubiquitin specific peptidase c family 0.001 0.0001 0.0002
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0173
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0251
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0002 0.0003
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.042 0.4412
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.001 0.0001 0.0002
Schistosoma mansoni thyroid hormone receptor 0.0159 0.1152 0.161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0092 0.0251
Schistosoma mansoni hypothetical protein 0.0011 0.0007 0.0009
Brugia malayi Regulator of G protein signaling domain containing protein 0.0011 0.0007 0.0019
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.001 0.0001 0.0004
Loa Loa (eye worm) transcription factor SMAD2 0.0404 0.3039 0.8261
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0037 0.0209 0.0568
Echinococcus multilocularis lamin dm0 0.0029 0.0149 0.0208
Brugia malayi nuclear receptor RXR 0.0012 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0023 0.0097 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0095
Brugia malayi hypothetical protein 0.001 0.0002 0.0007
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0092 0.0129
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0002 0.0007
Mycobacterium ulcerans lipoprotein LpqF 0.0215 0.1586 0.1532
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Loa Loa (eye worm) MBCTL1 0.0053 0.0328 0.0892
Entamoeba histolytica hypothetical protein 0.0011 0.0007 0.0035
Echinococcus granulosus intermediate filament protein 0.0029 0.0149 0.0208
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.042 0.0587
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.001 0.0001 0.0002
Treponema pallidum ribonuclease Z 0.0018 0.0064 0.4847
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.1597 0.4206
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0251
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0092 0.0251
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.001 0.0001 0.0053
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.004 0.0244
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0328 0.0459
Brugia malayi hypothetical protein 0.0012 0.0012 0.0033
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0002 0.0007
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0002 0.0003
Schistosoma mansoni intermediate filament proteins 0.0029 0.0149 0.0208
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0149 0.0406
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.001 0.0001 0.0002
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.001 0.0001 0.0002
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0097 0.0602
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0159 0.1152 0.161
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0095
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0233 0.1452
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0307 0.0429
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0279 0.039
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0004
Echinococcus multilocularis ras GTP exchange factor 0.0015 0.0034 0.0048
Toxoplasma gondii UBA/TS-N domain-containing protein 0.001 0.0001 0.0015
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.004 0.0056
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0015 0.0034 0.0048
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0028 0.0135 0.0188
Leishmania major hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative 0.0018 0.0064 0.0398
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0159 0.1152 0.161
Entamoeba histolytica alkyl sulfatase, putative 0.0018 0.0064 0.039
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.001 0.0001 0.0002
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.004 0.0424
Brugia malayi Isocitrate dehydrogenase 0.0015 0.004 0.011
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0012 0.0063
Schistosoma mansoni smad1 5 8 and 0.0028 0.0135 0.0188
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0307 0.0835
Entamoeba histolytica hypothetical protein 0.0027 0.0128 0.0793
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0018 0.0064 0.039
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Echinococcus granulosus microtubule associated protein 2 0.079 0.6025 0.8416
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0108
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0111 0.0685
Brugia malayi steroid hormone receptor 0.0022 0.0092 0.0251
Schistosoma mansoni regulator of G protein signaling 0.0011 0.0007 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0064 0.0164
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0233 0.0326
Loa Loa (eye worm) raf kinase 0.0099 0.0685 0.1862
Brugia malayi tailless protein 0.001 0.0002 0.0007
Entamoeba histolytica metallo-beta-lactamase family protein 0.0018 0.0064 0.039
Brugia malayi Pre-SET motif family protein 0.0064 0.042 0.1141
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.004 0.0056
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Echinococcus multilocularis axis inhibition protein axin 0.0011 0.0007 0.001
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.001 0.0001 0.0015
Mycobacterium tuberculosis Conserved protein 0.0018 0.0064 0.0023
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0012 0.0017
Onchocerca volvulus 0.001 0.0002 0.0003
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0088 0.0603 0.377
Brugia malayi mothers against decapentaplegic homolog 3 0.0012 0.0017 0.0046
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.004 0.0424
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0088 0.0603 0.1639
Trypanosoma brucei beta lactamase 0.0215 0.1586 0.9931
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.004 0.0056
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0215 0.1586 0.1552
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0307 0.0429
Schistosoma mansoni regulator of G protein signaling 0.0011 0.0007 0.001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0097 0.1024
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0168 0.1222 0.1707
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0012 0.0016 0.0043
Trypanosoma brucei protein kinase, putative 0.005 0.0309 0.1926
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0002 0.0003
Echinococcus multilocularis son of sevenless 1 0.0015 0.0034 0.0048
Echinococcus multilocularis Protein son of sevenless 0.0015 0.0034 0.0048
Mycobacterium tuberculosis Possible hydrolase 0.0018 0.0064 0.0023
Echinococcus multilocularis ETHE1 protein 0.0018 0.0064 0.0089
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0012 0.0067
Schistosoma mansoni cpg binding protein 0.0066 0.043 0.0601
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Schistosoma mansoni zinc phosphodiesterase 0.0018 0.0064 0.0089
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0092 0.0129
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0007 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0128 0.0793
Schistosoma mansoni inositol monophosphatase 0.004 0.0233 0.0326
Brugia malayi hypothetical protein 0.0024 0.0111 0.0301
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0685 0.0957
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Brugia malayi MH1 domain containing protein 0.0015 0.004 0.0108
Brugia malayi nuclear receptor NHR-88 0.0022 0.0092 0.0251
Entamoeba histolytica metallo-beta-lactamase family protein 0.0018 0.0064 0.039
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0092 0.0129
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0091 0.0622 0.0869
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.001 0.0001 0.0002
Trichomonas vaginalis beta lactamase domain, putative 0.0018 0.0064 0.0164
Echinococcus granulosus Pleckstrin G protein interacting region 0.002 0.0079 0.0111
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0092 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0064 0.0164
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0018 0.0064 0.039
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.001 0.0001 0.0053
Schistosoma mansoni hypothetical protein 0.0937 0.7159 1
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0279 0.039
Onchocerca volvulus 0.0346 0.2596 0.6839
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0015 0.0034 0.0048
Brugia malayi GoLoco motif family protein 0.0028 0.0136 0.0368
Echinococcus multilocularis mothers against decapentaplegic 2 0.0012 0.0017 0.0024
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Brugia malayi acetyltransferase, GNAT family protein 0.0168 0.1222 0.3321
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.001 0.0001 0.0002
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0217 0.1597 1
Brugia malayi MH1 domain containing protein 0.0028 0.0135 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.1597 0.4206
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0149 0.0406
Echinococcus multilocularis mothers against decapentaplegic 5 0.0028 0.0135 0.0188
Loa Loa (eye worm) inositol-1 0.004 0.0233 0.0634
Brugia malayi hypothetical protein 0.0159 0.1152 0.3132
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0092 0.0129
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.012 0.0167
Brugia malayi Muscleblind-like protein 0.0487 0.3679 1
Echinococcus multilocularis expressed protein 0.0011 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0031
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0328 0.0459
Trypanosoma brucei metallo-beta-lactamase-like protein, putative 0.0018 0.0064 0.039
Brugia malayi A-kinase anchor protein 10, precursor 0.0011 0.0007 0.0019
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0018 0.0064 0.039
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0015 0.0034 0.0206
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0002 0.0003
Onchocerca volvulus 0.0022 0.0092 0.024
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0092 0.0251
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0092 0.0129
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.012 0.0167
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0092 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0015
Plasmodium vivax ubiquitin specific protease, putative 0.001 0.0001 0.0027
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0097 0.0253
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0092 0.024
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0012 0.0063
Echinococcus granulosus L aminoadipate semialdehyde 0.0091 0.0622 0.0869
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0279 0.039
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.004 0.0244
Trichomonas vaginalis beta lactamase domain, putative 0.0018 0.0064 0.0164
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0233 0.146
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0092 0.0251
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.001 0.0001 0.0027
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0015 0.0034 0.0048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0068 0.0451 0.1226
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0018 0.0064 0.039
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0023 0.0097 0.0136
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.001 0.0001 0.0027
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0309 0.0431
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0547 0.0765
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.001 0.0001 0.0002
Brugia malayi hypothetical protein 0.0016 0.0044 0.0119
Leishmania major hypothetical protein, conserved 0.0051 0.0316 0.1977
Brugia malayi Inositol-1 0.004 0.0233 0.0634
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.1597 0.4206
Schistosoma mansoni zinc finger protein 0.001 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0279 0.0758
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.004 0.0244
Echinococcus granulosus regulator of G protein signaling 7 0.0031 0.0164 0.0229
Schistosoma mansoni smad 0.0012 0.0017 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0037 0.0095
Onchocerca volvulus 0.0066 0.043 0.1131
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0064 0.0023
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0037 0.0211 0.132
Brugia malayi CXXC zinc finger family protein 0.0066 0.043 0.1169
Brugia malayi intermediate filament protein 0.0029 0.0149 0.0406
Trypanosoma cruzi glyoxalase II 0.0018 0.0064 0.039
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0088 0.0603 0.1639
Brugia malayi regulator of G-protein signaling rgs-7 0.0011 0.0007 0.0019
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0088 0.0603 0.0842
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.001 0.0001 0.0027
Schistosoma mansoni hypothetical protein 0.0028 0.0136 0.0189
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0011 0.0007 0.0015
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0128 0.0793
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Brugia malayi mbt repeat family protein 0.0046 0.0279 0.0758
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0015 0.0034 0.0206
Echinococcus granulosus mixed lineage leukemia protein mll 0.0019 0.0066 0.0093
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0111 0.4134
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0018 0.0064 0.039
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.004 0.0244
Leishmania major metallo-beta-lactamase family protein-like protein 0.0018 0.0064 0.0398
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0002 0.0003
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.001 0.0001 0.0002
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.001 0.0001 0.0002
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0429 0.0599
Loa Loa (eye worm) Smad1 0.0028 0.0135 0.0366
Loa Loa (eye worm) hypothetical protein 0.0029 0.0145 0.0394
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0.0001 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0095
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0092 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0037 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0753 0.1981
Entamoeba histolytica hypothetical protein, conserved 0.0018 0.0064 0.039
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0119 0.0056
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0046
Entamoeba histolytica serine/threonine protein kinase, putative 0.0217 0.1597 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.001 0.0001 0.0002
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0086 0.0233
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0015
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.001 0.0001 0.0002
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0019 0.0066 0.0093
Loa Loa (eye worm) hypothetical protein 0.002 0.0079 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0218 0.057
Leishmania major hypothetical protein, conserved 0.0015 0.0037 0.0229
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0092 0.0251
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0008 0.0011
Brugia malayi PXA domain containing protein 0.0011 0.0007 0.0019
Entamoeba histolytica recQ family DNA helicase 0.0012 0.0012 0.0063
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.001 0.0001 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0307 0.0429
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.001 0.0001 0.0027
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.001 0.0001 0.0053
Entamoeba histolytica type A flavoprotein, putative 0.0018 0.0064 0.039
Plasmodium vivax hydroxyacyl glutathione hydrolase, putative 0.0018 0.0064 0.151
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0092 0.0129
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0309 0.0839
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0097 0.0602
Brugia malayi N-terminal motif family protein 0.0414 0.3116 0.847
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Brugia malayi MAP kinase sur-1 0.005 0.0309 0.0839
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.002 0.0079 0.0111
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0033
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0091 0.0622 0.1691
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0037 0.0211 0.1312
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0201 0.0138
Brugia malayi N-terminal motif family protein 0.0015 0.0034 0.0093
Brugia malayi Bromodomain containing protein 0.0041 0.024 0.0652
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0119 0.0079
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0015 0.0034 0.0048
Trichomonas vaginalis rotamase, putative 0.0037 0.0211 0.0552
Loa Loa (eye worm) hypothetical protein 0.0159 0.1152 0.3132
Brugia malayi hypothetical protein 0.002 0.0079 0.0216
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.042 0.0587
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0015 0.0034 0.0086
Echinococcus multilocularis segment polarity protein dishevelled 0.0023 0.0097 0.0136
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0264
Onchocerca volvulus 0.0015 0.0034 0.0086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0037 0.0095
Echinococcus granulosus expressed protein 0.0011 0.0007 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0015
Entamoeba histolytica metallo-beta-lactamase family protein 0.0018 0.0064 0.039
Echinococcus multilocularis L aminoadipate semialdehyde 0.0091 0.0622 0.0869
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0307 0.0429
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0279 0.039
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0251
Leishmania major hypothetical protein, conserved 0.0018 0.0064 0.0398
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0092 0.0251
Schistosoma mansoni DNA helicase recq5 0.0023 0.0097 0.0136
Schistosoma mansoni dishevelled 0.0023 0.0097 0.0136
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0092 0.0129
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.001 0.0001 0.0009
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0018 0.0064 0.039
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0441 0.3326 0.904
Brugia malayi hypothetical protein 0.001 0.0002 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0037 0.0095
Entamoeba histolytica hypothetical protein 0.0027 0.0128 0.0793
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0044 0.0119
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0309 0.081
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0309 0.0431

Activities

Activity type Activity value Assay description Source Reference
CD (binding) = 0.68 uM Induction of human NQO1 activity in mouse Hepa-1c1c7 cells assessed as concentration require for 2 fold induction after 48 hrs ChEMBL. 20392544
IC50 (functional) = 86.7 uM Antiplasmodial activity against Plasmodium falciparum FcB1/columbia infected in human erythrocytes ChEMBL. 20630767

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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