Detailed information for compound 1233677

Basic information

Technical information
  • TDR Targets ID: 1233677
  • Name: [(2S,3S)-2-(1,3-benzodioxol-5-yl)-7-methoxy-4 -oxochroman-3-yl] N-(3-bromo-4-methylphenyl)c arbamate
  • MW: 526.333 | Formula: C25H20BrNO7
  • H donors: 1 H acceptors: 2 LogP: 5.15 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc2c(c1)O[C@H]([C@@H](C2=O)OC(=O)Nc1ccc(c(c1)Br)C)c1ccc2c(c1)OCO2
  • InChi: 1S/C25H20BrNO7/c1-13-3-5-15(10-18(13)26)27-25(29)34-24-22(28)17-7-6-16(30-2)11-20(17)33-23(24)14-4-8-19-21(9-14)32-12-31-19/h3-11,23-24H,12H2,1-2H3,(H,27,29)/t23-,24+/m0/s1
  • InChiKey: KVWWZXIMTCPSMS-BJKOFHAPSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [(2S,3S)-2-(1,3-benzodioxol-5-yl)-7-methoxy-4-oxo-chroman-3-yl] N-(3-bromo-4-methyl-phenyl)carbamate
  • N-(3-bromo-4-methylphenyl)carbamic acid [(2S,3S)-2-(1,3-benzodioxol-5-yl)-7-methoxy-4-oxo-3-chromanyl] ester
  • N-(3-bromo-4-methyl-phenyl)carbamic acid [(2S,3S)-2-(1,3-benzodioxol-5-yl)-4-keto-7-methoxy-chroman-3-yl] ester
  • CMLD3_000108
  • CMLDBU00003667

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0036 0.006 0.0296
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0067 0.0067
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0056 0.0252
Onchocerca volvulus 0.0044 0.0081 0.0096
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0065 0.0142 0.0142
Brugia malayi Nuclear hormone receptor-like 1 0.0109 0.0267 0.036
Echinococcus granulosus RUN 0.014 0.0356 0.0356
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Schistosoma mansoni hypothetical protein 0.01 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0131 0.0131
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0044 0.0082 0.0109
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0075
Loa Loa (eye worm) doublecortin family protein 0.014 0.0356 0.0481
Brugia malayi histone deacetylase 11 0.0131 0.0331 0.0446
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0109 0.0267 0.0361
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0036 0.006 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0054 0.0241
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0122 0.0122
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0006 0.0027
Onchocerca volvulus Cathepsin F homolog 0.0051 0.0102 0.0124
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0109 0.0267 0.0267
Brugia malayi jmjC domain containing protein 0.0061 0.0131 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0056 0.0075
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0026 0.0032 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0098 0.0973
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0001 0.0001
Echinococcus multilocularis notch 0.0452 0.1246 0.1246
Schistosoma mansoni tyrosine kinase 0.0078 0.0179 0.0179
Echinococcus multilocularis insulin receptor 0.0047 0.009 0.009
Mycobacterium leprae Conserved hypothetical protein 0.0066 0.0146 0.2999
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0095
Echinococcus granulosus voltage gated potassium channel subunit 0.0045 0.0085 0.0085
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0057 0.0121 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0109 0.0267 0.0361
Onchocerca volvulus 0.0111 0.0275 0.0358
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Brugia malayi histone deacetylase 3 (HD3) 0.0366 0.1001 0.1351
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Echinococcus multilocularis neural cadherin 0.0452 0.1246 0.1246
Echinococcus multilocularis 0.0045 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Schistosoma mansoni histone deacetylase hda2 0.0131 0.0331 0.0331
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0053 0.0287
Brugia malayi prostaglandin transporter 0.0027 0.0035 0.0046
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0176 0.0176
Brugia malayi Inositol-1 0.0039 0.0067 0.009
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0075
Mycobacterium leprae Possible oxidoreductase 0.0045 0.0085 0.0989
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0031 0.0128
Schistosoma mansoni hypothetical protein 0.014 0.0356 0.0356
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0131 0.0178
Brugia malayi Serotonin receptor 0.0065 0.0142 0.0191
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0035 0.0035
Brugia malayi hypothetical protein 0.0051 0.0103 0.0138
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0035
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Echinococcus multilocularis fibropellin Ia 0.0452 0.1246 0.1246
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Schistosoma mansoni hypothetical protein 0.0216 0.0573 0.0573
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0083 0.0447
Echinococcus granulosus 7tm_1 domain containing protein 0.0065 0.0142 0.0142
Loa Loa (eye worm) animal heme peroxidase 0.261 0.7403 1
Echinococcus multilocularis sex peptide receptor 0.0065 0.0142 0.0142
Echinococcus granulosus p2X purinoceptor 4 0.0536 0.1485 0.1485
Leishmania major pyruvate kinase 0.0035 0.0056 0.0302
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0275 0.037
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0001 0.0001
Trypanosoma cruzi aldo-keto reductase 0.0111 0.0275 0.1493
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Entamoeba histolytica cysteine protease, putative 0.0051 0.0102 0.0776
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0031 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0109 0.0267 0.036
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0024 0.0024 0.0024
Brugia malayi hypothetical protein 0.016 0.0414 0.0558
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0658 0.1835 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0065 0.0142 0.0142
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0509 0.277
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0044 0.0082 0.0414
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0119 0.0616
Loa Loa (eye worm) histone deacetylase 11 0.0131 0.0331 0.0447
Schistosoma mansoni aldo-keto reductase 0.0111 0.0275 0.0275
Entamoeba histolytica hypothetical protein 0.0076 0.0174 0.1514
Echinococcus multilocularis fatty acid binding protein FABP2 0.0034 0.0054 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0064 0.0294
Onchocerca volvulus 0.0065 0.0142 0.0179
Schistosoma mansoni tyrosine kinase 0.0079 0.0181 0.0181
Onchocerca volvulus 0.0044 0.0081 0.0096
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0068 0.0676
Onchocerca volvulus 0.0065 0.0142 0.0179
Onchocerca volvulus 0.014 0.0356 0.0468
Echinococcus multilocularis p2X purinoceptor 4 0.0536 0.1485 0.1485
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0036 0.006 0.0296
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0121 0.0162
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Plasmodium vivax flavodoxin domain containing protein 0.0023 0.0023 0.0224
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0045 0.0085 0.0846
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Leishmania major aldo-keto reductase-like protein 0.0111 0.0275 0.1493
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0085 0.04
Brugia malayi GCC2 and GCC3 family protein 0.0452 0.1246 0.1683
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Giardia lamblia High cysteine protein 0.0452 0.1246 1
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0014
Onchocerca volvulus Dual oxidase homolog 0.261 0.7403 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0057 0.0121 0.0163
Echinococcus granulosus sex peptide receptor 0.0065 0.0142 0.0142
Echinococcus granulosus neuropeptide receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) DR-78 0.0051 0.0103 0.0139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Echinococcus granulosus delta-like protein 1 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Schistosoma mansoni cell polarity protein 0.0452 0.1246 0.1246
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0109 0.0267 0.0361
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0036 0.006 0.0296
Echinococcus granulosus histone deacetylase 6 0.0131 0.0331 0.0331
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0177 0.0461 0.2508
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0119 0.0642
Brugia malayi Calcium binding EGF domain containing protein 0.0452 0.1246 0.1683
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0045 0.0085 0.068
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0028 0.011
Schistosoma mansoni retinoic acid receptor RXR 0.0206 0.0543 0.0543
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0057 0.0307
Brugia malayi hypoxia-induced factor 1 0.0148 0.0379 0.0511
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Mycobacterium ulcerans glyoxalase GloA 0.0044 0.0082 0.0414
Echinococcus multilocularis dna polymerase kappa 0.004 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Onchocerca volvulus 0.006 0.0129 0.016
Echinococcus granulosus cpg binding protein 0.0064 0.0139 0.0139
Schistosoma mansoni glutamate receptor AMPA 0.0064 0.014 0.014
Leishmania major DNA polymerase kappa, putative 0.0021 0.0016 0.0082
Leishmania major histone deacetylase, putative 0.0131 0.0331 0.1801
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0006 0.0007
Onchocerca volvulus 0.0051 0.0103 0.0126
Leishmania major cathepsin L-like protease 0.0193 0.0509 0.277
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0082 0.0414
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.0014
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0086 0.0439
Echinococcus multilocularis musashi 0.0114 0.0281 0.0281
Schistosoma mansoni hypothetical protein 0.0065 0.0142 0.0142
Schistosoma mansoni P2X receptor subunit 0.0229 0.0611 0.0611
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Schistosoma mansoni tyrosine kinase 0.0146 0.0375 0.0375
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0068 0.0505
Giardia lamblia Aldose reductase 0.0111 0.0275 0.2167
Onchocerca volvulus Protein ultraspiracle homolog 0.0109 0.0267 0.0347
Onchocerca volvulus 0.0027 0.0035 0.0034
Echinococcus multilocularis lamin 0.0114 0.0281 0.0281
Giardia lamblia Pyruvate kinase 0.0018 0.0008 0.0016
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0006 0.004
Echinococcus granulosus lamin dm0 0.0114 0.0281 0.0281
Brugia malayi AKH receptor 0.0065 0.0142 0.0191
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0056 0.0076
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0095
Leishmania major histone deacetylase, putative 0.0366 0.1001 0.5454
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0024 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Brugia malayi hypothetical protein 0.014 0.0356 0.048
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0509 0.277
Brugia malayi nuclear receptor NHR-88 0.0051 0.0103 0.0138
Schistosoma mansoni lamin 0.0114 0.0281 0.0281
Loa Loa (eye worm) TK/EGFR protein kinase 0.0146 0.0375 0.0506
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0006
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0109 0.0267 0.0267
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0079 0.0079
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0096
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Brugia malayi Cathepsin L-like precursor 0.0034 0.0054 0.0072
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.001 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0174 0.0174
Echinococcus multilocularis nuclear receptor nhr 48 0.0051 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus neuropeptide Y receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0035 0.0056 0.0076
Echinococcus multilocularis epidermal growth factor receptor 0.0079 0.0181 0.0181
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0065 0.0142 0.0191
Schistosoma mansoni glutamate receptor NMDA 0.0152 0.0391 0.0391
Schistosoma mansoni neuropeptide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0209 0.0209
Echinococcus granulosus intermediate filament protein 0.0114 0.0281 0.0281
Plasmodium vivax vivapain-1 0.0026 0.0031 0.0307
Plasmodium falciparum aldehyde reductase, putative 0.0045 0.0085 0.0846
Echinococcus multilocularis neuropeptides capa receptor 0.0065 0.0142 0.0142
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) nuclear receptor NHR-67 0.0051 0.0103 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0031 0.0167
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0057 0.0307
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0452 0.1246 0.1246
Loa Loa (eye worm) intermediate filament protein 0.0114 0.0281 0.0379
Echinococcus multilocularis glutamate receptor NMDA 0.0126 0.0316 0.0316
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0072 0.0332
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0076 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Onchocerca volvulus 0.0102 0.0249 0.0323
Onchocerca volvulus Slit protein homolog 0.0452 0.1246 0.1672
Brugia malayi Phospholipase A2 family protein 0.0185 0.0485 0.0655
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0109 0.0267 0.0267
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0081 0.0109
Leishmania major cysteine peptidase A (CPA) 0.0051 0.0102 0.055
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0097 0.0959
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi Thioredoxin reductase 0.005 0.0098 0.0132
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0109 0.0267 0.0347
Echinococcus multilocularis neurogenic locus protein delta 0.0452 0.1246 0.1246
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.0776 1
Echinococcus multilocularis neuropeptide receptor A26 0.2015 0.5705 0.5705
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0036 0.006 0.0296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Plasmodium vivax aldehyde reductase, putative 0.0045 0.0085 0.0846
Echinococcus granulosus neural cadherin 0.0452 0.1246 0.1246
Onchocerca volvulus 0.0044 0.0081 0.0096
Onchocerca volvulus 0.0051 0.0102 0.0124
Echinococcus multilocularis histone deacetylase 6 0.0131 0.0331 0.0331
Schistosoma mansoni biogenic amine receptor 0.0065 0.0142 0.0142
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0045 0.0085 0.0085
Schistosoma mansoni histamine h1 receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Onchocerca volvulus 0.0027 0.0035 0.0034
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0026 0.0032 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0275 0.135
Loa Loa (eye worm) notch protein 0.0452 0.1246 0.1683
Schistosoma mansoni hypothetical protein 0.0251 0.0672 0.0672
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0036 0.006 0.0296
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.003 0.029
Loa Loa (eye worm) TK/INSR protein kinase 0.0047 0.009 0.0122
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0079 0.0181 0.0181
Echinococcus granulosus glutamate NMDA receptor subunit 0.0152 0.0391 0.0391
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0103 0.0103
Brugia malayi Cadherin domain containing protein 0.0452 0.1246 0.1683
Brugia malayi hypothetical protein 0.014 0.0356 0.048
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0362
Schistosoma mansoni biogenic amine receptor 0.0065 0.0142 0.0142
Onchocerca volvulus Peroxidase homolog 0.261 0.7403 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus aldehyde reductase 0.0066 0.0146 0.0146
Trypanosoma cruzi aldo/keto reductase, putative 0.0111 0.0275 0.1493
Echinococcus multilocularis neuropeptide receptor 0.0065 0.0142 0.0142
Giardia lamblia DINP protein human, muc B family 0.0021 0.0016 0.0081
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0036 0.006 0.0296
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0083 0.0447
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus multilocularis aldo keto reductase 0.0111 0.0275 0.0275
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0026 0.0032 0.0142
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0072 0.0388
Onchocerca volvulus 0.0111 0.0275 0.0358
Trypanosoma brucei histone deacetylase 1 0.0366 0.1001 0.5454
Onchocerca volvulus 0.0027 0.0035 0.0034
Echinococcus multilocularis G protein coupled receptor 139 0.0065 0.0142 0.0142
Plasmodium falciparum nitric oxide synthase, putative 0.0026 0.0032 0.0309
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0102 0.0102
Echinococcus granulosus aldo keto reductase 0.0111 0.0275 0.0275
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.01 0.0242 0.0326
Trypanosoma cruzi p450 reductase, putative 0.0026 0.0032 0.0169
Schistosoma mansoni biogenic amine (5HT) receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus granulosus aldo keto reductase 0.0111 0.0275 0.0275
Echinococcus multilocularis p2X purinoceptor 4 0.0536 0.1485 0.1485
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0031 0.0167
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Echinococcus granulosus geminin 0.0346 0.0945 0.0945
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0359 0.0359
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.068 0.0919
Loa Loa (eye worm) hypothetical protein 0.0216 0.0573 0.0773
Brugia malayi Nuclear hormone receptor E75 0.0051 0.0103 0.0138
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0083 0.0581
Echinococcus multilocularis nmda type glutamate receptor 0.0138 0.0351 0.0351
Giardia lamblia Aldose reductase 0.0111 0.0275 0.2167
Schistosoma mansoni hypothetical protein 0.0427 0.1174 0.1174
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi hypothetical protein 0.0051 0.0103 0.0138
Echinococcus multilocularis pyruvate kinase 0.0018 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0109 0.0267 0.036
Leishmania major histone deacetylase, putative 0.0366 0.1001 0.5454
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0111 0.0275 0.1493
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Plasmodium vivax unspecified product 0.0026 0.0031 0.0307
Echinococcus granulosus allatostatin A receptor 0.0065 0.0142 0.0142
Echinococcus granulosus agrin 0.0019 0.001 0.001
Loa Loa (eye worm) inositol-1 0.0039 0.0067 0.0091
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0119 0.0642
Schistosoma mansoni agrin 0.0019 0.001 0.001
Onchocerca volvulus 0.0044 0.0081 0.0096
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0103 0.0103
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0056 0.0062
Onchocerca volvulus 0.0035 0.0058 0.0064
Echinococcus granulosus histone deacetylase 7 0.0131 0.0331 0.0331
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0102 0.0102
Loa Loa (eye worm) cytochrome P450 family protein 0.0075 0.017 0.023
Brugia malayi Furin-like cysteine rich region family protein 0.0146 0.0375 0.0505
Brugia malayi hypothetical protein 0.0017 0.0004 0.0004
Toxoplasma gondii aldo-keto reductase 0.0045 0.0085 0.068
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0121 0.0162
Echinococcus granulosus cytochrome P450 2K1 0.0036 0.006 0.006
Trypanosoma brucei histone deacetylase 3 0.0131 0.0331 0.1801
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0031 0.0055
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0036 0.006 0.0296
Mycobacterium ulcerans oxidoreductase 0.0111 0.0275 0.1469
Loa Loa (eye worm) hypothetical protein 0.0185 0.0485 0.0656
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0082 0.0381
Loa Loa (eye worm) ctsf protein 0.0051 0.0102 0.0137
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trypanosoma cruzi aldo/keto reductase, putative 0.0045 0.0085 0.0462
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0119 0.0642
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0057 0.0121 0.0121
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Toxoplasma gondii protease inhibitor PI2 0.0019 0.001 0.0075
Schistosoma mansoni RAR-like nuclear receptor 0.0109 0.0267 0.0267
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0109 0.0267 0.036
Echinococcus multilocularis fmrfamide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0109 0.0267 0.0267
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0148 0.0379 0.0379
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0045 0.0085 0.04
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0016 0.0085
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0119 0.0908
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0075
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0231 0.0311
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0036 0.006 0.0296
Loa Loa (eye worm) FAD binding domain-containing protein 0.0016 0.0003 0.0004
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0658 0.1835 1
Entamoeba histolytica histone deacetylase, putative 0.0366 0.1001 1
Brugia malayi SPARC precursor 0.0019 0.001 0.0013
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Echinococcus granulosus 7TM GPCR rhodopsin 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0056 0.0553
Brugia malayi Melatonin receptor type 1A 0.0065 0.0142 0.0191
Onchocerca volvulus 0.0099 0.0241 0.0312
Onchocerca volvulus 0.0065 0.0142 0.0179
Schistosoma mansoni laminin gamma-3 chain 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0095
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Echinococcus granulosus glutamate receptor 2 0.0053 0.0107 0.0107
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0275 0.135
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0629 0.175 0.2364
Schistosoma mansoni cytochrome P450 0.0036 0.006 0.006
Brugia malayi Serotonin receptor 0.0065 0.0142 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0016 0.0082
Onchocerca volvulus 0.0452 0.1246 0.1672
Brugia malayi Protein kinase domain containing protein 0.0047 0.009 0.0121
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi hypothetical protein 0.0044 0.0081 0.0109
Loa Loa (eye worm) cytochrome P450 0.0036 0.006 0.0081
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0109 0.0267 0.036
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0129 0.0174
Echinococcus multilocularis lamin dm0 0.0114 0.0281 0.0281
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.01 0.0242 0.0242
Echinococcus multilocularis histone deacetylase 6 0.0131 0.0331 0.0331
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0152 0.0391 0.0391
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0776 0.7689
Loa Loa (eye worm) hypothetical protein 0.014 0.0356 0.0481
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Brugia malayi orphan nuclear receptor NR2E1 0.0051 0.0103 0.0138
Onchocerca volvulus 0.0051 0.0102 0.0124
Onchocerca volvulus 0.0027 0.0035 0.0034
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0051 0.0399
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0189 0.0496 0.2699
Schistosoma mansoni lipoxygenase 0.0837 0.2345 0.2345
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0036 0.006 0.0296
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi Pre-SET motif family protein 0.0629 0.175 0.2363
Plasmodium falciparum cysteine proteinase falcipain 3 0.0051 0.0102 0.1009
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3429 0.9739 0.9739
Echinococcus multilocularis histone deacetylase 1 0.0366 0.1001 0.1001
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0056 0.0444
Loa Loa (eye worm) hypothetical protein 0.01 0.0241 0.0326
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0114 0.0281 0.0379
Brugia malayi Peroxidasin 0.261 0.7403 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0085 0.04
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.001 0.0013
Echinococcus granulosus p2X purinoceptor 4 0.0536 0.1485 0.1485
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0045 0.0085 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Schistosoma mansoni histone deacetylase 4 5 0.0131 0.0331 0.0331
Echinococcus granulosus aldo keto reductase 0.0111 0.0275 0.0275
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Echinococcus multilocularis histone deacetylase 0.0131 0.0331 0.0331
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0102 0.0102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0067 0.0422
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Echinococcus granulosus dro:myosuppressin receptor 0.0065 0.0142 0.0142
Brugia malayi nuclear hormone receptor family member odr-7 0.0051 0.0103 0.0138
Schistosoma mansoni opsin-like receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0051 0.0102 0.0124
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Brugia malayi Blistered cuticle protein 3 0.261 0.7403 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0109 0.0267 0.0361
Echinococcus granulosus nuclear receptor nhr 48 0.0051 0.0103 0.0103
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0056 0.0062
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0019 0.0024
Trypanosoma brucei aldo-keto reductase, putative 0.0111 0.0275 0.1493
Brugia malayi hypothetical protein 0.261 0.7403 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0275 0.0371
Schistosoma mansoni alpha-1 adrenergic receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0026 0.0035
Echinococcus multilocularis peroxidasin 0.261 0.7403 0.7403
Brugia malayi intermediate filament protein 0.0114 0.0281 0.0378
Echinococcus multilocularis aldehyde reductase 0.0066 0.0146 0.0146
Loa Loa (eye worm) G-protein coupled receptor 0.0065 0.0142 0.0192
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0026 0.0032 0.0032
Echinococcus multilocularis RUN 0.014 0.0356 0.0356
Echinococcus granulosus neurogenic locus notch protein 0.0452 0.1246 0.1246
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0026 0.0032 0.0032
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0658 0.1835 1
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0054 0.0054
Loa Loa (eye worm) glutathione reductase 0.005 0.0098 0.0133
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0217 0.0217
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0658 0.1835 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0096
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Plasmodium falciparum thioredoxin reductase 0.0017 0.0006 0.005
Brugia malayi CXXC zinc finger family protein 0.006 0.0129 0.0173
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Plasmodium vivax glyoxalase I, putative 0.0189 0.0496 0.495
Echinococcus granulosus p2X purinoceptor 4 0.0536 0.1485 0.1485
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0109 0.0267 0.0267
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Brugia malayi G-protein coupled receptor 0.0065 0.0142 0.0191
Echinococcus multilocularis pyruvate kinase 0.0018 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0036 0.006 0.0296
Echinococcus multilocularis Polycystic kidney disease protein 0.014 0.0356 0.0356
Echinococcus granulosus follistatin 0.0019 0.001 0.001
Echinococcus granulosus cathepsin l1 0.0034 0.0054 0.0054
Schistosoma mansoni loxhd1 0.014 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Mycobacterium ulcerans glyoxalase GloA 0.0044 0.0082 0.0414
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0036 0.006 0.0296
Mycobacterium tuberculosis Probable reductase 0.0113 0.0279 0.1495
Brugia malayi ecdysteroid receptor 0.0109 0.0267 0.036
Schistosoma mansoni cpg binding protein 0.0064 0.0139 0.0139
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0008 0.0056
Entamoeba histolytica hypothetical protein 0.0076 0.0174 0.1514
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0036 0.006 0.0296
Schistosoma mansoni follistatin 0.0019 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0031 0.0128
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0065 0.0142 0.0142
Plasmodium falciparum pyruvate kinase 0.0035 0.0056 0.0553
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0056 0.0075
Echinococcus multilocularis thyroid hormone receptor alpha 0.0359 0.0982 0.0982
Echinococcus granulosus g protein coupled receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) animal heme peroxidase 0.261 0.7403 1
Loa Loa (eye worm) oxidoreductase 0.0044 0.0081 0.011
Loa Loa (eye worm) animal heme peroxidase 0.261 0.7403 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi hypothetical protein 0.0471 0.1299 0.1754
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0051 0.0103 0.0103
Schistosoma mansoni inositol monophosphatase 0.0039 0.0067 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0083 0.0386
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis histone deacetylase 6 0.0131 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0109 0.0267 0.0361
Loa Loa (eye worm) glutamate receptor 2 0.0064 0.014 0.0189
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0837 0.2345 0.2345
Echinococcus granulosus pyruvate kinase 0.0035 0.0056 0.0056
Brugia malayi polk-prov protein 0.0031 0.0044 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0072 0.0361
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0209 0.0209
Leishmania major cytochrome p450-like protein 0.0036 0.006 0.0323
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Entamoeba histolytica aldose reductase, putative 0.0111 0.0275 0.2549
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.0097 1
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0102 0.0124
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0026 0.0032 0.0032
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0079 0.0625
Mycobacterium ulcerans hypothetical protein 0.0045 0.0085 0.0435
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0019 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0362
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0302 0.242
Giardia lamblia Hypothetical protein 0.0023 0.0023 0.014
Giardia lamblia Pyruvate kinase 0.0035 0.0056 0.0405
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.003 0.0158
Brugia malayi hypothetical protein 0.0057 0.0121 0.0162
Brugia malayi nuclear hormone receptor 0.0051 0.0103 0.0138
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Schistosoma mansoni peroxidasin 0.261 0.7403 0.7403
Brugia malayi cathepsin L-like precursor 0.0034 0.0054 0.0072
Brugia malayi Cadherin domain containing protein 0.0452 0.1246 0.1683
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0097 0.0959
Brugia malayi NADH-dependent xylose reductase 0.0045 0.0085 0.0114
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Brugia malayi hypothetical protein 0.0027 0.0035 0.0046
Echinococcus multilocularis nmda type glutamate receptor 0.015 0.0384 0.0384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0031 0.0129
Echinococcus granulosus neurogenic locus notch protein 4 0.0452 0.1246 0.1246
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0036 0.006 0.0296
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Onchocerca volvulus Peroxidasin homolog 0.261 0.7403 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0051 0.0102 0.0137
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0001
Plasmodium falciparum histone deacetylase 1 0.0366 0.1001 1
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0045 0.0085 0.0462
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0083 0.0112
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0047 0.009 0.009
Echinococcus granulosus serotonin receptor 0.0065 0.0142 0.0142
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0027
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0083 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0036 0.006 0.0296
Brugia malayi histone deacetylase 1 (HD1) 0.0366 0.1001 0.1351
Plasmodium vivax vivapain-2 0.0051 0.0102 0.1009
Echinococcus granulosus L aminoadipate semialdehyde 0.0174 0.0454 0.0454
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0031 0.0031
Echinococcus multilocularis neurogenic locus notch protein 0.0452 0.1246 0.1246
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0109 0.0267 0.0267
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0006 0.0027
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0014
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0086 0.0116
Schistosoma mansoni ATP-binding cassette transporter 0.0064 0.014 0.014
Brugia malayi hypothetical protein 0.0076 0.0174 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0055 0.0113 0.0113
Brugia malayi putative neuropeptide receptor NPR1 0.0065 0.0142 0.0191
Schistosoma mansoni opsin-like receptor 0.0065 0.0142 0.0142
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0065 0.0142 0.0142
Echinococcus granulosus neurogenic locus notch protein 0.0452 0.1246 0.1246
Echinococcus granulosus nmda type glutamate receptor 0.015 0.0384 0.0384
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0098 0.0133
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0036 0.006 0.0323
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0109 0.0267 0.0267
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0109 0.0267 0.0347
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.0097 0.0497
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0072 0.0388
Loa Loa (eye worm) hypothetical protein 0.0131 0.0331 0.0447
Entamoeba histolytica hypothetical protein 0.0076 0.0174 0.1514
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Brugia malayi Tachykinin-like peptides receptor 99D 0.0065 0.0142 0.0191
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0001 0.0001
Schistosoma mansoni ap endonuclease 0.0057 0.0119 0.0119
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0031 0.0167
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0035 0.0046
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0095
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.0279 0.1495
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0009 0.0009
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Schistosoma mansoni steroid hormone receptor ad4bp 0.0109 0.0267 0.0267
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0098 0.0098
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0034 0.0054 0.0071
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0081 0.0109
Loa Loa (eye worm) hypothetical protein 0.0053 0.0107 0.0145
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0035 0.0035
Echinococcus multilocularis agrin 0.0019 0.001 0.001
Schistosoma mansoni peroxidasin 0.261 0.7403 0.7403
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0174 0.0174
Loa Loa (eye worm) nuclear hormone receptor 0.0051 0.0103 0.0139
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0065 0.0142 0.0142
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0044 0.0081 0.0096
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0109 0.0267 0.036
Onchocerca volvulus 0.0452 0.1246 0.1672
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Echinococcus granulosus cathepsin l1 0.0051 0.0102 0.0102
Echinococcus multilocularis g-protein coupled receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0043
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0083 0.0447
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0024 0.0024 0.0024
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0658 0.1835 1
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) TYRA-2 protein 0.0065 0.0142 0.0192
Brugia malayi flavodoxin family protein 0.0026 0.0032 0.0042
Schistosoma mansoni lipoxygenase 0.0585 0.1626 0.1626
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0362
Echinococcus granulosus single minded 2 0.0035 0.0058 0.0058
Trypanosoma cruzi major cysteine proteinase, putative 0.0152 0.0391 0.2125
Loa Loa (eye worm) neuropeptide F receptor 0.0065 0.0142 0.0192
Plasmodium vivax histone deacetylase, putative 0.0131 0.0331 0.3303
Onchocerca volvulus 0.0065 0.0142 0.0179
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.0315 0.1691
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Schistosoma mansoni microtubule-associated protein tau 0.352 1 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0068 0.0435
Brugia malayi tailless protein 0.0051 0.0103 0.0138
Echinococcus granulosus histone deacetylase 6 0.0131 0.0331 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0082 0.0381
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0076 0.0174 0.0174
Echinococcus granulosus glutamate receptor NMDA 0.0126 0.0316 0.0316
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0024 0.0024 0.0024
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0275 0.135
Toxoplasma gondii thioredoxin reductase 0.005 0.0098 0.0782
Echinococcus granulosus peptide allatostatin:somatostatin 0.0065 0.0142 0.0142
Echinococcus granulosus nmda type glutamate receptor 0.0138 0.0351 0.0351
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.003 0.0158
Brugia malayi Pre-SET motif family protein 0.0091 0.0217 0.0292
Echinococcus granulosus slit 2 protein 0.0452 0.1246 0.1246
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0001 0.0001
Brugia malayi FAD binding domain containing protein 0.0016 0.0003 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Toxoplasma gondii cathepsin CPL 0.0051 0.0102 0.081
Echinococcus multilocularis FTZ F1 alpha 0.0109 0.0267 0.0267
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0034 0.0054 0.0072
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0051 0.0103 0.0103
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.0097 0.077
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0119 0.0616
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0058 0.0284
Mycobacterium ulcerans epoxide hydrolase EphA 0.0161 0.0415 0.2236
Schistosoma mansoni glutamate receptor kainate 0.0064 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Schistosoma mansoni pol-related 0.0111 0.0275 0.0275
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0051 0.0103 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0109 0.0267 0.0361
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0031 0.0055
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0251 0.0672 0.0672
Echinococcus multilocularis pyruvate kinase 0.0035 0.0056 0.0056
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0192 0.0505 0.0683
Onchocerca volvulus 0.0051 0.0102 0.0124
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Leishmania major p450 reductase, putative 0.0026 0.0032 0.0169
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Plasmodium vivax glutathione reductase, putative 0.005 0.0098 0.0973
Echinococcus granulosus fmrfamide receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0119 0.0566
Entamoeba histolytica alcohol dehydrogenase, putative 0.0045 0.0085 0.0609
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0109 0.0267 0.0267
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0011 0.0011
Trypanosoma cruzi cruzipain precursor, putative 0.0193 0.0509 0.277
Onchocerca volvulus 0.0045 0.0085 0.0102
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0031 0.0167
Echinococcus granulosus g protein coupled receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Schistosoma mansoni tyrosine kinase 0.0079 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus multilocularis aldo keto reductase 0.0111 0.0275 0.0275
Plasmodium falciparum glutathione reductase 0.005 0.0098 0.0973
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0065 0.0142 0.0142
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0251 0.0672 0.0672
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0001 0.0001
Onchocerca volvulus 0.014 0.0356 0.0468
Echinococcus multilocularis neuropeptide Y receptor 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus granulosus cysteine protease 0.0026 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0054 0.0241
Echinococcus granulosus protein jagged 1 0.0452 0.1246 0.1246
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0072 0.0388
Onchocerca volvulus 0.261 0.7403 1
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0035 0.0035
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0058 0.0077
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.1299 0.1299
Onchocerca volvulus 0.0051 0.0102 0.0124
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.003 0.029
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0005 0.0022
Schistosoma mansoni hypothetical protein 0.0346 0.0945 0.0945
Schistosoma mansoni glutamate receptor NMDA 0.0202 0.0533 0.0533
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0142 0.0142
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni P2X receptor subunit 0.0536 0.1485 0.1485
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0001 0.0001
Echinococcus multilocularis neuropeptide Y receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.001 0.0019
Loa Loa (eye worm) animal heme peroxidase 0.261 0.7403 1
Echinococcus granulosus glutamate receptor 2 0.0076 0.0174 0.0174
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0119 0.0159
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0016 0.0082
Brugia malayi Calcium binding EGF domain containing protein 0.0452 0.1246 0.1683
Onchocerca volvulus 0.0452 0.1246 0.1672
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0072 0.0361
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0014
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0044 0.0081 0.0109
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Toxoplasma gondii histone deacetylase HDAC2 0.0366 0.1001 0.8032
Echinococcus multilocularis geminin 0.0346 0.0945 0.0945
Onchocerca volvulus 0.261 0.7403 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0006 0.0027
Loa Loa (eye worm) Notch2 0.0452 0.1246 0.1683
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0371 0.0371
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0056 0.0062
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Onchocerca volvulus 0.0065 0.0142 0.0179
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0075
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0031 0.0055
Echinococcus multilocularis NMDA receptor 0.0024 0.0024 0.0024
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0051 0.0103 0.0103
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.001 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0031 0.0041
Echinococcus multilocularis microtubule associated protein 2 0.352 1 1
Brugia malayi dehydrogenases, short chain protein 2 0.0044 0.0081 0.0109
Leishmania major hypothetical protein, conserved 0.0026 0.003 0.0158
Schistosoma mansoni hypothetical protein 0.0076 0.0174 0.0174
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0095
Plasmodium vivax SET domain protein, putative 0.0091 0.0217 0.2164
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0119 0.1464
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0072 0.0388
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0057 0.0121 0.0121
Toxoplasma gondii cytochrome p450 superfamily protein 0.0036 0.006 0.0476
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.0315 0.1691
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0056 0.0275
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0142 0.0142
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0051 0.0103 0.0103
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.068 0.0918
Echinococcus granulosus peroxidasin 0.261 0.7403 0.7403
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0009 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0109 0.0267 0.036
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Schistosoma mansoni cpg binding protein 0.0064 0.0139 0.0139
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0016 0.0055
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0067 0.0308
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0036 0.006 0.0296
Plasmodium falciparum glutathione reductase 0.0017 0.0006 0.005
Schistosoma mansoni adenoreceptor 0.0065 0.0142 0.0142
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0111 0.0275 0.7268
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0119 0.1177
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Plasmodium vivax unspecified product 0.0017 0.0005 0.0039
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0098 0.0505
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Echinococcus granulosus fibropellin Ia 0.0452 0.1246 0.1246
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0119 0.0642
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0119 0.0119
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0032 0.0169
Schistosoma mansoni neuropeptide f receptor 76f 0.0065 0.0142 0.0142
Brugia malayi M-phase phosphoprotein, mpp8 0.0099 0.0241 0.0324
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0379 0.0512
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0109 0.0267 0.0267
Onchocerca volvulus 0.0065 0.0142 0.0179
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0044 0.0082 0.011
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0067 0.0336
Brugia malayi nuclear hormone receptor 0.0109 0.0267 0.036
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0109 0.0267 0.0267
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0065 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0065 0.0142 0.0142
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0031 0.0167
Mycobacterium ulcerans short chain dehydrogenase 0.0044 0.0081 0.0412
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi N-terminal motif family protein 0.0187 0.0491 0.0662
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0057 0.0121 0.0121
Onchocerca volvulus 0.0111 0.0275 0.0358
Brugia malayi nuclear receptor NHR-88 0.0109 0.0267 0.036
Brugia malayi Cytochrome P450 family protein 0.0045 0.0086 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0056 0.0275
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0073
Schistosoma mansoni histone deacetylase hda2 0.0131 0.0331 0.0331
Giardia lamblia Nitric oxide synthase, inducible 0.0023 0.0023 0.014
Echinococcus granulosus pyruvate kinase 0.0018 0.0008 0.0008
Plasmodium vivax histone deacetylase, putative 0.0131 0.0331 0.3303
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.0505 0.0505
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0174 0.0174
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0032 0.0132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Brugia malayi Cytochrome P450 family protein 0.0036 0.006 0.008
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0056 0.0076
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0097 0.0523
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0452 0.1246 0.1683
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Echinococcus granulosus ecdysone induced protein 78C 0.0109 0.0267 0.0267
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Echinococcus multilocularis expressed protein 0.0019 0.001 0.001
Schistosoma mansoni lamin 0.0114 0.0281 0.0281
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0217 0.0217
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Trypanosoma brucei aldo/keto reductase, putative 0.0045 0.0085 0.0462
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0217 0.0217
Echinococcus multilocularis G-protein coupled receptor, putative 0.0065 0.0142 0.0142
Trypanosoma brucei trypanothione reductase 0.005 0.0098 0.0531
Echinococcus granulosus histone deacetylase 6 0.0131 0.0331 0.0331
Schistosoma mansoni P2X receptor subunit 0.0536 0.1485 0.1485
Onchocerca volvulus 0.0065 0.0142 0.0179
Schistosoma mansoni hypothetical protein 0.01 0.0242 0.0242
Schistosoma mansoni hypothetical protein 0.01 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0006
Echinococcus multilocularis histone deacetylase 7 0.0131 0.0331 0.0331
Brugia malayi Doublecortin family protein 0.014 0.0356 0.048
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0026 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0051 0.0103 0.0138
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.0279 0.1495
Brugia malayi GnHR receptor homolog 0.0065 0.0142 0.0191
Loa Loa (eye worm) hypothetical protein 0.0174 0.0454 0.0613
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0056 0.0302
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0102 0.0776
Echinococcus granulosus biogenic amine 5HT receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0086 0.0465
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Onchocerca volvulus 0.0114 0.0281 0.0366
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.003 0.0233
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0031 0.0055
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0045 0.0085 0.0114
Entamoeba histolytica alcohol dehydrogenase, putative 0.0045 0.0085 0.0609
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0275 0.037
Echinococcus multilocularis neuropeptide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni biogenic amine receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0085 0.04
Plasmodium vivax vivapain-3 0.0026 0.0031 0.0307
Brugia malayi Glutamate receptor 2 precursor 0.0064 0.014 0.0187
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0189 0.0496 0.2699
Echinococcus granulosus neuropeptides capa receptor 0.0065 0.0142 0.0142
Brugia malayi conserved hypotetical protein 0.0051 0.0103 0.0138
Onchocerca volvulus 0.0051 0.0103 0.0126
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0051 0.0103 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0065 0.0142 0.0142
Toxoplasma gondii exonuclease III APE 0.0057 0.0119 0.0945
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0241 0.0325
Echinococcus multilocularis histone deacetylase 3 0.0366 0.1001 0.1001
Brugia malayi jmjC domain containing protein 0.0058 0.0122 0.0163
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0032 0.0169
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0036 0.006 0.0296
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus GPCR family 2 0.01 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis cathepsin L 0.0026 0.0031 0.0031
Brugia malayi PAS domain containing protein 0.0048 0.0093 0.0125
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Schistosoma mansoni thyroid hormone receptor 0.0359 0.0982 0.0982
Schistosoma mansoni polycystin 1-related 0.014 0.0356 0.0356
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0432 0.057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0051 0.0102 0.1009
Echinococcus granulosus alpha 1A adrenergic receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0007 0.0005
Onchocerca volvulus Peroxidasin homolog 0.261 0.7403 1
Echinococcus granulosus G protein coupled receptor 139 0.0065 0.0142 0.0142
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0109 0.0267 0.0267
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Loa Loa (eye worm) hypothetical protein 0.01 0.0242 0.0327
Schistosoma mansoni tyrosine kinase 0.0078 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi Delta serrate ligand family protein 0.0452 0.1246 0.1683
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0036 0.006 0.0296
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0056 0.0302
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0059
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0119 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0065 0.0142 0.0192
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0006
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0032 0.0169
Onchocerca volvulus 0.0051 0.0102 0.0124
Brugia malayi Nuclear hormone receptor E75 0.0051 0.0103 0.0138
Mycobacterium leprae Conserved hypothetical protein 0.0036 0.006 0.0145
Schistosoma mansoni aldo-keto reductase 0.0111 0.0275 0.0275
Echinococcus granulosus neuropeptide s receptor 0.2015 0.5705 0.5705
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0067 0.545
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0054 0.0285
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0122 0.0122
Echinococcus multilocularis pyruvate kinase 0.0018 0.0008 0.0008
Schistosoma mansoni cpg binding protein 0.006 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0014
Echinococcus multilocularis protein jagged 2 0.0452 0.1246 0.1246
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0036 0.006 0.0296
Echinococcus multilocularis allatostatin A receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0079 0.0365
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0039 0.0165
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.0505 0.0505
Echinococcus granulosus glutamate receptor subunit protein glur 0.0024 0.0024 0.0024
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0076 0.0174 0.0174
Brugia malayi Calcitonin receptor-like protein seb-1 0.0316 0.0858 0.1157
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Plasmodium falciparum thioredoxin reductase 0.005 0.0098 0.0973
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0131 0.0131
Leishmania major cathepsin L-like protease 0.0193 0.0509 0.277
Loa Loa (eye worm) melatonin receptor type 1A 0.0065 0.0142 0.0192
Brugia malayi hypothetical protein 0.01 0.0241 0.0324
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0065 0.0142 0.0191
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0079 0.0625
Brugia malayi G-protein coupled receptor 0.0065 0.0142 0.0191
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0035 0.0274
Onchocerca volvulus 0.0051 0.0102 0.0124
Echinococcus granulosus pyruvate kinase 0.0035 0.0056 0.0056
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0056 0.0252
Trypanosoma brucei histone deacetylase, putative 0.0131 0.0331 0.1801
Onchocerca volvulus 0.0715 0.1998 0.2688
Brugia malayi FAD binding domain containing protein 0.0026 0.0032 0.0042
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.0505 0.0505
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Onchocerca volvulus Chorion peroxidase homolog 0.261 0.7403 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0036 0.006 0.0296
Loa Loa (eye worm) histone deacetylase 7A 0.0131 0.0331 0.0447
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.004
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.003 0.0158
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Onchocerca volvulus Phospholipase A2 homolog 0.0185 0.0485 0.0643
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0065 0.0142 0.0192
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0079 0.0365
Echinococcus multilocularis L aminoadipate semialdehyde 0.0174 0.0454 0.0454
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0044 0.0082 0.0082
Echinococcus granulosus Nuclear hormone receptor HR96 0.0051 0.0103 0.0103
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0109 0.0267 0.0361
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0142 0.0142
Trichomonas vaginalis set domain proteins, putative 0.0715 0.1997 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0047 0.009 0.009
Schistosoma mansoni inositol monophosphatase 0.0039 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0036 0.006 0.0296
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0174 0.0454 0.0612
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Schistosoma mansoni pyruvate kinase 0.0018 0.0008 0.0008
Brugia malayi Intermediate filament tail domain containing protein 0.0114 0.0281 0.0378
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0122 0.0122
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0035 0.0046
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Onchocerca volvulus Neuropeptide F receptor homolog 0.0065 0.0142 0.0179
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0072 0.0388
Echinococcus granulosus histone deacetylase 1 0.0366 0.1001 0.1001
Echinococcus multilocularis neurogenic locus notch protein 0.0452 0.1246 0.1246
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0019 0.0026
Loa Loa (eye worm) histone deacetylase 0.0131 0.0331 0.0447
Leishmania major prostaglandin f synthase, putative 0.0111 0.0275 0.1493
Schistosoma mansoni rab6-interacting 0.014 0.0356 0.0356
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0206 0.0543 0.0543
Leishmania major cytochrome P450 reductase, putative 0.0023 0.0023 0.0122
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Onchocerca volvulus 0.0065 0.0142 0.0179
Schistosoma mansoni opsin-like receptor 0.0065 0.0142 0.0142
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0026 0.0032 0.0169
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0452 0.1246 0.1672
Onchocerca volvulus Neurogenic locus notch homolog 0.0452 0.1247 0.1672
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0044 0.0081 0.0096
Entamoeba histolytica aldose reductase, putative 0.0111 0.0275 0.2549
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0093 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0366 0.1001 0.4998
Echinococcus multilocularis histone deacetylase 8 0.0131 0.0331 0.0331
Echinococcus granulosus neurogenic locus protein delta 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0109 0.0267 0.0267
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0357 0.1919
Echinococcus multilocularis glutamate receptor 2 0.0064 0.014 0.014
Schistosoma mansoni thyroid hormone receptor 0.0359 0.0982 0.0982
Loa Loa (eye worm) glutamate receptor 1 0.0064 0.014 0.0189
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0001 0.0001
Echinococcus multilocularis 0.0036 0.006 0.006
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0006 0.005
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0001 0.0001
Schistosoma mansoni P2X receptor subunit 0.0229 0.0611 0.0611
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Schistosoma mansoni cathepsin s 0.0017 0.0005 0.0005
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0023 0.0023 0.0087
Trypanosoma brucei unspecified product 0.0034 0.0053 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis cpg binding protein 0.0064 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0026 0.0032 0.0309
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0204 0.0204
Echinococcus granulosus histone deacetylase 8 0.0131 0.0331 0.0331
Echinococcus multilocularis lipoxygenase domain containing protein 0.014 0.0356 0.0356
Leishmania major cytochrome p450-like protein 0.0045 0.0086 0.0465
Echinococcus granulosus histone deacetylase 0.0131 0.0331 0.0331
Schistosoma mansoni histone deacetylase 1 2 3 0.0131 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Echinococcus multilocularis orexin receptor type 2 0.0065 0.0142 0.0142
Schistosoma mansoni neuropeptide F-like receptor 0.0065 0.0142 0.0142
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.001 0.0013
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.003 0.029
Schistosoma mansoni notch 0.0452 0.1247 0.1247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0102 0.0137
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis neuropeptides capa receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0096
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0024 0.0024 0.0024
Plasmodium falciparum LCCL domain-containing protein 0.014 0.0356 0.3551
Schistosoma mansoni biogenic amine (5HT) receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Plasmodium falciparum aldo-keto reductase, putative 0.0045 0.0085 0.0846
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0016 0.0003 0.0003
Echinococcus multilocularis protein jagged 1 0.0452 0.1246 0.1246
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0111 0.0275 0.1493
Schistosoma mansoni hypothetical protein 0.0096 0.0231 0.0231
Brugia malayi Glutamate receptor 1 precursor 0.0064 0.014 0.0187
Brugia malayi neuropeptide F receptor 0.0065 0.0142 0.0191
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0065 0.0142 0.0142
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0081 0.0646
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0006 0.005
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus multilocularis cysteine protease 0.0051 0.0102 0.0102
Brugia malayi steroid hormone receptor 0.0109 0.0267 0.036
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Plasmodium falciparum histone deacetylase, putative 0.0131 0.0331 0.3303
Giardia lamblia Histone deacetylase 0.0366 0.1001 0.8024
Schistosoma mansoni glutamate receptor kainate 0.0064 0.014 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0142 0.0142
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0217 0.0217
Brugia malayi Latrophilin receptor protein 2 0.01 0.0242 0.0326
Echinococcus granulosus FTZ F1 alpha 0.0109 0.0267 0.0267
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0316 0.0858 0.1157
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0102 0.0136
Echinococcus multilocularis aldo keto reductase 0.0111 0.0275 0.0275
Schistosoma mansoni slit 0.0452 0.1246 0.1246
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0076 0.0174 0.0174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) histone deacetylase 3 0.0366 0.1001 0.1352
Schistosoma mansoni hypothetical protein 0.01 0.0242 0.0242
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.01 0.0242 0.0242
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.0097 0.0523
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0044 0.0235
Echinococcus granulosus insulin receptor 0.0047 0.009 0.009
Echinococcus granulosus Polycystic kidney disease protein 0.014 0.0356 0.0356
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0366 0.1001 0.4998
Echinococcus granulosus epidermal growth factor receptor 0.0079 0.0181 0.0181
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0189 0.0496 0.067
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus granulosus neuropeptide FF receptor 2 0.0065 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0109 0.0267 0.036
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0076 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0073
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0192 0.0505 0.0682
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0174 0.0454 0.0454
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0008 0.007
Brugia malayi nuclear hormone receptor family member nhr-6 0.0051 0.0103 0.0138
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0061 0.013 0.0176
Mycobacterium leprae putative cytochrome p450 0.0036 0.006 0.0145
Echinococcus multilocularis follistatin 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Brugia malayi Steroid receptor seven-up type 2 0.0109 0.0267 0.036
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0035 0.0035
Schistosoma mansoni neuropeptide F-like receptor 0.0065 0.0142 0.0142
Echinococcus granulosus cathepsin L cysteine proteinase 0.0051 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0073
Schistosoma mansoni glutamate receptor kainate 0.0064 0.014 0.014
Echinococcus multilocularis somatostatin receptor 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0065 0.0142 0.0179
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0102 0.0776
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0275 0.135
Onchocerca volvulus Histone deacetylase 10 homolog 0.0131 0.0331 0.0434
Echinococcus granulosus g-protein coupled receptor 0.0065 0.0142 0.0142
Brugia malayi latrophilin 2 splice variant baaae 0.0216 0.0573 0.0772
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0036 0.006 0.0296
Loa Loa (eye worm) fibroinase 0.0051 0.0102 0.0137
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0051 0.0103 0.0139
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Echinococcus multilocularis GPCR, family 2 0.01 0.0242 0.0242
Schistosoma mansoni histone deacetylase 0.0366 0.1001 0.1001
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.0279 0.7421
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0024 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0065 0.0142 0.0142
Entamoeba histolytica hypothetical protein 0.0076 0.0174 0.1514
Echinococcus granulosus cathepsin l cysteine peptidase 0.0051 0.0102 0.0102
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0006 0.005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0331 0.0331
Brugia malayi sulfakinin receptor protein 0.0065 0.0142 0.0191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0076 0.0174 0.0174
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0008 0.007
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0083 0.0083
Schistosoma mansoni histone deacetylase 0.0366 0.1001 0.1001
Schistosoma mansoni hypothetical protein 0.0036 0.006 0.006
Schistosoma mansoni organic anion transporter 0.0027 0.0035 0.0035
Brugia malayi Histone deacetylase 1 0.0366 0.1001 0.1351
Echinococcus granulosus dna polymerase kappa 0.004 0.0072 0.0072
Loa Loa (eye worm) neuropeptide F receptor 0.0065 0.0142 0.0192
Schistosoma mansoni ap endonuclease 0.0057 0.0119 0.0119
Onchocerca volvulus Bile acid receptor homolog 0.0109 0.0267 0.0347
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0031 0.0129
Brugia malayi Cathepsin L-like precursor 0.0034 0.0054 0.0072
Trichomonas vaginalis sulfite reductase, putative 0.0026 0.0032 0.013
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.0315 0.8615
Echinococcus multilocularis p2X purinoceptor 4 0.0536 0.1485 0.1485
Schistosoma mansoni nuclear receptor 0.0051 0.0103 0.0103
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0065 0.0142 0.0191
Brugia malayi nuclear receptor RXR 0.0051 0.0103 0.0138
Echinococcus multilocularis serotonin receptor 0.0065 0.0142 0.0142
Brugia malayi G protein-coupled receptor F59B2.13 0.0065 0.0142 0.0191
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0086 0.0116
Schistosoma mansoni survival motor neuron protein 0.0096 0.0231 0.0231
Echinococcus granulosus histone deacetylase 3 0.0366 0.1001 0.1001
Mycobacterium tuberculosis Conserved protein 0.0044 0.0082 0.0414
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0366 0.1001 0.4998
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0031 0.0031
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.0315 0.1691
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0006 0.0027
Toxoplasma gondii EGF family domain-containing protein 0.0452 0.1246 1
Schistosoma mansoni fatty acid binding protein 0.0034 0.0054 0.0054
Brugia malayi nuclear receptor RXR 0.0057 0.0121 0.0162
Echinococcus granulosus lipoxygenase domain containing protein 0.014 0.0356 0.0356
Echinococcus multilocularis pyruvate kinase 0.0035 0.0056 0.0056
Brugia malayi ORL1-like opioid receptor 0.0065 0.0142 0.0191
Onchocerca volvulus 0.0099 0.0241 0.0312
Loa Loa (eye worm) hypothetical protein 0.0187 0.0491 0.0663
Echinococcus granulosus dnaJ subfamily B 0.0427 0.1174 0.1174
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0109 0.0267 0.036
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0658 0.1835 1
Brugia malayi RE15519p 0.0065 0.0142 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus granulosus notch 0.0452 0.1246 0.1246
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0032 0.0169
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0065 0.0142 0.0142
Brugia malayi ecdysone receptor 0.0051 0.0103 0.0138
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Onchocerca volvulus Putative protein 0.0044 0.0082 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0044 0.0082 0.0414
Echinococcus multilocularis dro:myosuppressin receptor 0.0065 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0109 0.0267 0.036
Onchocerca volvulus 0.0114 0.0281 0.0366
Plasmodium vivax glyoxalase I, putative 0.0044 0.0082 0.0808
Brugia malayi Dopamine receptor 0.0065 0.0142 0.0191
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Brugia malayi neuropeptide F receptor 0.0065 0.0142 0.0191
Brugia malayi putative neuropeptide receptor 0.0065 0.0142 0.0191
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0001 0.0001
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0109 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0055 0.0113 0.0153
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0109 0.0267 0.0267
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Brugia malayi Calcium binding EGF domain containing protein 0.0452 0.1246 0.1683
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0035 0.0034
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0065 0.0142 0.0142
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0056 0.0076
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0057 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0081 0.0109
Onchocerca volvulus 0.261 0.7403 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0122 0.0122
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.0505 0.0505
Echinococcus multilocularis pyruvate kinase 0.0027 0.0035 0.0035
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0056 0.0014
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0217 0.1738
Plasmodium falciparum glyoxalase I 0.0189 0.0496 0.495
Schistosoma mansoni neuropeptide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis aldo keto reductase 0.0111 0.0275 0.0275
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Echinococcus multilocularis slit 2 protein 0.0452 0.1246 0.1246
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0371 0.05
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Mycobacterium leprae conserved hypothetical protein 0.0049 0.0097 0.1362
Brugia malayi Dopamine receptor protein 1 0.0065 0.0142 0.0191
Schistosoma mansoni septate junction protein 0.0452 0.1246 0.1246
Loa Loa (eye worm) histone deacetylase 1 0.0366 0.1001 0.1352
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.0097 0.0497
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0065 0.0142 0.0142
Echinococcus granulosus hypothetical protein 0.0111 0.0275 0.0275
Loa Loa (eye worm) acetyltransferase 0.0145 0.0371 0.0501
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0086 0.0116
Entamoeba histolytica hypothetical protein 0.0049 0.0097 0.0724
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0044 0.0081 0.0412
Schistosoma mansoni pyruvate kinase 0.0035 0.0056 0.0056
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0086 0.0465
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0086 0.0465
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0119 0.0119
Schistosoma mansoni tyrosine kinase 0.0047 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0275 0.135
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0119 0.016
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0065 0.0142 0.0192
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Echinococcus multilocularis cysteine protease 0.0051 0.0102 0.0102
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0035 0.0047
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.0279 0.1495
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0076 0.0174 0.0174
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0056 0.0273
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0142 0.0142
Echinococcus multilocularis epidermal growth factor receptor 0.0146 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0114 0.0281 0.0379
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0006 0.0027
Echinococcus granulosus neuropeptides capa receptor 0.0065 0.0142 0.0142
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.01 0.0242 0.0242
Echinococcus multilocularis lipoxygenase domain containing protein 0.014 0.0356 0.0356
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) hypothetical protein 0.0111 0.0275 0.0371
Toxoplasma gondii histone deacetylase HDAC4 0.0131 0.0331 0.2653
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Brugia malayi hypothetical protein 0.0026 0.003 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0457 0.2267
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0275 0.037
Leishmania major pyruvate kinase 0.0035 0.0056 0.0302
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus multilocularis dnaJ subfamily B 0.0427 0.1174 0.1174
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0036 0.006 0.0296
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0031 0.0307
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.01 0.0242 0.0242
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus granulosus thyroid hormone receptor alpha 0.0051 0.0103 0.0103
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0067 0.0308
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0009 0.0009
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0036 0.006 0.0296
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0065 0.0142 0.0142
Mycobacterium tuberculosis Conserved protein 0.0045 0.0085 0.0435
Schistosoma mansoni potassium channel beta 0.0045 0.0085 0.0085
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0036 0.006 0.0296
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0109 0.0267 0.0267
Echinococcus multilocularis fmrfamide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni single-minded 0.0048 0.0093 0.0093
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0031 0.0031
Echinococcus granulosus somatostatin receptor 0.0065 0.0142 0.0142
Schistosoma mansoni myosin xvIII 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0109 0.0267 0.036
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Brugia malayi larval opioid receptor 0.0065 0.0142 0.0191
Onchocerca volvulus 0.0065 0.0142 0.0179
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0006 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0006
Toxoplasma gondii glyoxalase I, putative 0.0189 0.0496 0.3975
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0083 0.0111
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0189 0.0496 0.0657
Loa Loa (eye worm) hypothetical protein 0.0091 0.0217 0.0293
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0056 0.0302
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Brugia malayi photoreceptor-specific nuclear receptor 0.0109 0.0267 0.036
Echinococcus multilocularis protein jagged 1 0.0452 0.1246 0.1246
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0209 0.0209
Onchocerca volvulus 0.0096 0.0231 0.0298
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0102 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Echinococcus granulosus neuropeptide receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0083 0.0386
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0142 0.0142
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.0279 0.1495
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Brugia malayi hypothetical protein 0.0027 0.0035 0.0046
Brugia malayi G protein-coupled receptor 0.0065 0.0142 0.0191
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0371 0.0371
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0011 0.0011
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0056 0.0302
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0275 0.135
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0051 0.0103 0.0103
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0045 0.0085 0.068
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0065 0.0142 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0044 0.0235
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0072 0.0388
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Loa Loa (eye worm) latrophilin receptor protein 2 0.01 0.0242 0.0327
Schistosoma mansoni tyrosine kinase 0.0047 0.009 0.009
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0006 0.0027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Mycobacterium leprae conserved hypothetical protein 0.0044 0.0082 0.0861
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0036 0.006 0.0296
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0067 0.0308
Brugia malayi Histone deacetylase family protein 0.0131 0.0331 0.0446
Echinococcus multilocularis neurogenic locus notch protein 4 0.0452 0.1246 0.1246
Schistosoma mansoni hypothetical protein 0.0346 0.0945 0.0945
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0036 0.006 0.0296
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0031 0.0055
Brugia malayi Muscle positioning protein 4 0.0452 0.1246 0.1683
Echinococcus granulosus g protein coupled receptor 0.0065 0.0142 0.0142
Schistosoma mansoni organic anion transporter 0.0027 0.0035 0.0035
Echinococcus granulosus lipoxygenase domain containing protein 0.014 0.0356 0.0356
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.0505 0.0505
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0005 0.0006
Schistosoma mansoni rab6-interacting 0.014 0.0356 0.0356
Loa Loa (eye worm) blistered cuticle protein 3 0.261 0.7403 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0014
Loa Loa (eye worm) G-protein coupled receptor 0.0065 0.0142 0.0192
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.1299 0.1299
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0083 0.0447
Trypanosoma brucei histone deacetylase 2 0.0131 0.0331 0.1801
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.0097 0.077
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0028 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0036 0.006 0.0296
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.0097 0.0497
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0006 0.005
Mycobacterium tuberculosis Conserved protein 0.0044 0.0082 0.0414
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.0279 0.1495
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Onchocerca volvulus 0.0174 0.0454 0.06
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus granulosus protein jagged 1 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0053 0.0107 0.0145
Schistosoma mansoni neuropeptide receptor 0.0065 0.0142 0.0142
Toxoplasma gondii histone deacetylase HDAC3 0.0366 0.1001 0.8032
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0067 0.0533
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Brugia malayi nuclear receptor NHR-67 0.0051 0.0103 0.0138
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Toxoplasma gondii glyoxalase family protein 0.0044 0.0082 0.0649
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0161 0.0415 0.2236
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0209 0.0209
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0119 0.0948
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus granulosus cathepsin L 0.0026 0.0031 0.0031
Brugia malayi Dopamine receptor protein 2 0.0065 0.0142 0.0191
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0051 0.0102 0.1009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0109 0.0267 0.036
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0006 0.0292
Schistosoma mansoni nuclear receptor nhr-48 0.0051 0.0103 0.0103
Leishmania major cathepsin L-like protease 0.0193 0.0509 0.277
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0217 0.0217
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Schistosoma mansoni zinc finger protein 0.0051 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.0065 0.0142 0.0142
Onchocerca volvulus Putative cubilin 0.0452 0.1246 0.1672
Brugia malayi notch-like transmembrane receptor 0.0452 0.1246 0.1683
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0036 0.006 0.0296
Trypanosoma brucei prostaglandin f synthase 0.0111 0.0275 0.1493
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0036 0.006 0.0296
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Schistosoma mansoni pyruvate kinase 0.0035 0.0056 0.0056
Leishmania major cytochrome p450-like protein 0.0036 0.006 0.0323
Onchocerca volvulus 0.0111 0.0275 0.0358
Entamoeba histolytica aldose reductase, putative 0.0111 0.0275 0.2549
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0065 0.0142 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Brugia malayi glutathione reductase 0.005 0.0098 0.0132
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0054 0.0072
Echinococcus multilocularis neuropeptide FF receptor 2 0.0065 0.0142 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0065 0.0142 0.0142
Echinococcus granulosus fatty acid binding protein FABP2 0.0034 0.0054 0.0054
Onchocerca volvulus 0.0111 0.0275 0.0358
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0065 0.0142 0.0192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0102 0.0124
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0065 0.0142 0.0191
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Loa Loa (eye worm) steroid hormone receptor 0.0109 0.0267 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0275 0.037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Brugia malayi cytochrome P450 0.0036 0.006 0.008
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0103 0.0103
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0102 0.0102
Echinococcus granulosus phd:f box containing protein 0.0015 0.0001 0.0001
Plasmodium vivax vivapain-2 0.0051 0.0102 0.1009
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.0014
Echinococcus multilocularis fat cadherin tumor suppressor 0.0452 0.1246 0.1246
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0119 0.0566
Onchocerca volvulus 0.0452 0.1246 0.1672
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Leishmania major protein kinase, putative 0.0016 0.0004 0.0016
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0109 0.0267 0.036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0096
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Plasmodium falciparum histone deacetylase 2 0.0131 0.0331 0.3303
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0109 0.0267 0.0267
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0055 0.0113 0.0113
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0027
Plasmodium vivax histone deacetylase 1, putative 0.0366 0.1001 1
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Chlamydia trachomatis pyruvate kinase 0.0035 0.0056 0.5663
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0083 0.0386
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus multilocularis neuropeptide s receptor 0.2015 0.5705 0.5705
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.001 0.0013
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Schistosoma mansoni coup transcription factor 0.0109 0.0267 0.0267
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0083 0.0581
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0119 0.1177
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0189 0.0496 0.2699
Echinococcus granulosus hypothetical protein 0.0065 0.0142 0.0142
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0065 0.0142 0.0142
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.0097 0.8064
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0031 0.0055
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0065 0.0142 0.0142
Brugia malayi Histone deacetylase family protein 0.0131 0.0331 0.0446
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0362
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus multilocularis glutamate receptor 2 0.0053 0.0107 0.0107
Toxoplasma gondii histone deacetylase HDAC5 0.0131 0.0332 0.2656
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0036 0.006 0.0296
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0065 0.0142 0.0142
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0316 0.0858 0.1158
Echinococcus multilocularis methionine synthase reductase 0.0016 0.0003 0.0003
Brugia malayi cytoplasmic intermediate filament protein 0.0061 0.013 0.0175
Schistosoma mansoni nuclear receptor 0.0051 0.0103 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0036 0.006 0.0296
Schistosoma mansoni gynecophoral canal protein 0.0044 0.0082 0.0082
Schistosoma mansoni glutamate receptor AMPA 0.0064 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0102 0.055
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0776 0.7689
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0065 0.0142 0.0142
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0009 0.0009
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.001 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0032 0.0132
Loa Loa (eye worm) hypothetical protein 0.016 0.0414 0.0559
Schistosoma mansoni tyrosine kinase 0.0078 0.0179 0.0179
Brugia malayi SET domain containing protein 0.0016 0.0002 0.0002
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0079 0.0778
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0031 0.0167
Onchocerca volvulus 0.0452 0.1246 0.1672
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0024 0.0024 0.0024
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Leishmania major trypanothione reductase 0.005 0.0098 0.0531
Giardia lamblia GTOR 0.0044 0.0083 0.062
Trypanosoma cruzi histone deacetylase 1, putative 0.0366 0.1001 0.5454
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0109 0.0267 0.036
Echinococcus multilocularis voltage gated potassium channel subunit 0.0045 0.0085 0.0085
Echinococcus granulosus methionine synthase reductase 0.0016 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0036 0.006 0.0296
Schistosoma mansoni fatty acid binding protein 0.0034 0.0054 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0083 0.0447
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.0097 0.118
Echinococcus granulosus neuropeptide Y receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis neurogenic locus protein delta 0.0452 0.1246 0.1246
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0036 0.006 0.0296
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Loa Loa (eye worm) FAD binding domain-containing protein 0.0026 0.0032 0.0043
Schistosoma mansoni cytochrome P450 reductase 0.0026 0.0032 0.0032
Echinococcus granulosus pyruvate kinase 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Toxoplasma gondii aldose reductase, putative 0.0111 0.0275 0.2198
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Echinococcus granulosus Nuclear hormone receptor HR96 0.0051 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0051 0.0102 0.0137
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0142 0.0142
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Echinococcus multilocularis ecdysone induced protein 78C 0.0109 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Brugia malayi follicle stimulating hormone receptor 0.0065 0.0142 0.0191
Echinococcus granulosus protein jagged 2 0.0452 0.1246 0.1246
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0102 0.0482
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0187 0.0491 0.065
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Onchocerca volvulus Phospholipase A2 homolog 0.0185 0.0485 0.0643
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0001 0.0001
Plasmodium vivax histone deacetylase 2, putative 0.0131 0.0331 0.3303
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0085 0.04
Onchocerca volvulus Peroxidase homolog 0.261 0.7403 1
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0035 0.0034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.0505 0.0505
Mycobacterium tuberculosis Conserved protein TB27.3 0.0044 0.0082 0.0414
Plasmodium falciparum glyoxalase I 0.0044 0.0082 0.0808
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0837 0.2345 0.2345
Leishmania major histone deacetylase, putative 0.0131 0.0331 0.1801
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0036 0.006 0.0296
Echinococcus granulosus lamin 0.0114 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0471 0.1299 0.1755
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0076 0.0174 0.0174
Echinococcus multilocularis glutamate receptor 2 0.0076 0.0174 0.0174
Onchocerca volvulus 0.0034 0.0054 0.0059
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0036 0.006 0.0296
Echinococcus granulosus pyruvate kinase 0.0018 0.0008 0.0008
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus fatty acid binding protein FABP2 0.0034 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.014 0.0356 0.0481
Trypanosoma cruzi histone deacetylase 1, putative 0.0366 0.1001 0.5454
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.0776 0.6207
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0036 0.006 0.0296
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0065 0.0142 0.0191
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0457 0.2267
Onchocerca volvulus 0.0027 0.0035 0.0034
Schistosoma mansoni intermediate filament proteins 0.0114 0.0281 0.0281
Echinococcus multilocularis fatty acid binding protein FABP2 0.0034 0.0054 0.0054
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0509 0.277
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0005 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0098 0.0531
Echinococcus granulosus neuropeptide receptor A26 0.2015 0.5705 0.5705
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0035 0.0046
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0026 0.0032 0.0169
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0072 0.0332
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0109 0.0267 0.0267
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Trypanosoma brucei histone deacetylase 4 0.0131 0.0331 0.1801
Plasmodium vivax multidomain scavenger receptor, putative 0.014 0.0356 0.3551
Loa Loa (eye worm) cysteine protease 0.0051 0.0102 0.0137
Loa Loa (eye worm) hypothetical protein 0.0185 0.0485 0.0656
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0109 0.0267 0.0267
Brugia malayi Cytochrome P450 family protein 0.0075 0.017 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0032 0.0132
Mycobacterium tuberculosis Probable oxidoreductase 0.0111 0.0275 0.1469
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0109 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0366 0.1001 0.1352
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis serotonin receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0006 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0041 0.0178
Toxoplasma gondii histone deacetylase HDAC1 0.0131 0.0331 0.2653
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0036 0.006 0.0296
Schistosoma mansoni neuropeptide receptor 0.0065 0.0142 0.0142
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0098 0.0098
Brugia malayi lactoylglutathione lyase 0.0189 0.0496 0.0669
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0357 1
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0357 0.1919
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0051 0.0103 0.0103
Echinococcus granulosus protein jagged 2 0.0452 0.1246 0.1246
Echinococcus granulosus orexin receptor type 2 0.0065 0.0142 0.0142
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.001 0.0014
Echinococcus granulosus Solute carrier family 22 5 0.2033 0.5758 0.5758
Echinococcus granulosus epidermal growth factor receptor 0.0146 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0031 0.0031
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Loa Loa (eye worm) hypothetical protein 0.0316 0.0858 0.1158
Brugia malayi Cytochrome P450 family protein 0.0045 0.0086 0.0115
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Brugia malayi hypothetical protein 0.0057 0.0121 0.0162
Schistosoma mansoni histone deacetylase 4 5 0.0131 0.0331 0.0331
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0065 0.0142 0.0179
Onchocerca volvulus 0.0111 0.0275 0.0358
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0009 0.0009
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0083 0.0447
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0035 0.0186

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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