Detailed information for compound 1347291

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 409.457 | Formula: C18H23N3O6S
  • H donors: 2 H acceptors: 5 LogP: 2.77 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(COC(=O)CSc1ccc(cc1[N+](=O)[O-])C(=O)N)NCC1CCCCC1
  • InChi: 1S/C18H23N3O6S/c19-18(24)13-6-7-15(14(8-13)21(25)26)28-11-17(23)27-10-16(22)20-9-12-4-2-1-3-5-12/h6-8,12H,1-5,9-11H2,(H2,19,24)(H,20,22)
  • InChiKey: HTYBYJDSHWTWDR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0013 0.0097 0.0256
Leishmania major cytochrome p450-like protein 0.0042 0.0529 0.1453
Schistosoma mansoni vav2 0.0013 0.0097 0.0097
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0013 0.0097 0.0097
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0013 0.0097 0.0256
Loa Loa (eye worm) hypothetical protein 0.0023 0.025 0.0504
Loa Loa (eye worm) cytochrome P450 family protein 0.0042 0.0529 0.1066
Echinococcus multilocularis actin binding protein anillin 0.0013 0.0097 0.0097
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0024 0.027 0.2544
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0113 0.1598 0.1598
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0005 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.025 0.068
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0018 0.0175 0.0343
Brugia malayi Cytochrome P450 family protein 0.0042 0.0529 0.1066
Onchocerca volvulus 0.0013 0.0097 0.2204
Echinococcus multilocularis nervana 2 0.0212 0.3074 0.3074
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0013 0.0097 0.0186
Schistosoma mansoni coup transcription factor 0.0012 0.0086 0.0086
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0086 0.0086
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0247 0.361 1
Loa Loa (eye worm) hypothetical protein 0.0096 0.1344 0.2708
Entamoeba histolytica protein kinase, putative 0.0018 0.0175 0.0343
Onchocerca volvulus Protein melted homolog 0.0013 0.0097 0.2204
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0113 0.1598 0.3221
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0018 0.0175 0.0471
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0022 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0338 0.4963 1
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0086 0.0086
Entamoeba histolytica hypothetical protein, conserved 0.0013 0.0097 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Echinococcus granulosus pleckstrin y domain containing family A 0.0013 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0162 0.0326
Echinococcus granulosus cytohesin 1 0.0013 0.0097 0.0097
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.025 0.0494
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0021 0.0032
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0013 0.0097 0.0097
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0024 0.027 0.3371
Trichomonas vaginalis AGC family protein kinase 0.0126 0.1792 0.3605
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0522 0.1041
Onchocerca volvulus 0.0013 0.0097 0.2204
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0013 0.0097 0.0256
Schistosoma mansoni ferritin 0.001 0.0057 0.0057
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.001
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.1048 0.2188
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0086 0.0174
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0052 0.013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0163 0.0328
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0097 0.0186
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.025 0.3115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0148 0.182
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0013 0.0097 0.0186
Trypanosoma brucei protein kinase, putative 0.0018 0.0175 0.0343
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Schistosoma mansoni cytochrome P450 0.0024 0.027 0.027
Trypanosoma cruzi NIMA-related kinase, putative 0.0018 0.0175 0.0471
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.1048 0.2892
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0086 0.0086
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0064 0.0064
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0247 0.361 0.727
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0018 0.0175 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0247 0.361 0.727
Brugia malayi TBC domain containing protein 0.0013 0.0097 0.0196
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Trichomonas vaginalis AGC family protein kinase 0.0338 0.4963 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0022 0.0045
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0113 0.1598 0.3221
Echinococcus multilocularis muscleblind protein 0.018 0.2607 0.2607
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0163 0.0328
Trypanosoma cruzi hypothetical protein 0.0013 0.0097 0.0256
Schistosoma mansoni growth factor receptor-bound protein 0.0013 0.0097 0.0097
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0013 0.0097 0.0196
Onchocerca volvulus 0.0013 0.0097 0.2204
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0032 0.0032
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0731 0.1473
Trichomonas vaginalis helicase, putative 0.0008 0.0021 0.0032
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0086 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0653 0.6218
Schistosoma mansoni smad1 5 8 and 0.0008 0.0022 0.0022
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0024 0.027 0.2544
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.1598 0.1598
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0005 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0792 1
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0013 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.1048 0.1048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0021 0.0032
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0013 0.0097 0.0097
Schistosoma mansoni smad 0.0008 0.0022 0.0022
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.025 0.0494
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.361 0.361
Brugia malayi PH domain containing protein 0.0013 0.0097 0.0196
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0024 0.027 0.2544
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Schistosoma mansoni smad1 5 8 and 0.0008 0.0022 0.0022
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0024 0.027 0.0736
Brugia malayi MH2 domain containing protein 0.0117 0.165 0.3325
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0013 0.0097 0.0196
Schistosoma mansoni Smad4 0.0008 0.0022 0.0022
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.165 0.3325
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0086 0.0086
Schistosoma mansoni oxysterol-binding protein 1 0.0013 0.0097 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0086 0.0174
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.025 0.2351
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.025 0.2351
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Echinococcus granulosus serine/threonine protein kinase 0.023 0.3346 0.3346
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0653 0.0653
Loa Loa (eye worm) hypothetical protein 0.0051 0.0661 0.1331
Loa Loa (eye worm) AGC/PKN protein kinase 0.0113 0.1598 0.3221
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0024 0.027 0.3371
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0086 0.0174
Loa Loa (eye worm) AGC/PKA protein kinase 0.0247 0.361 0.7273
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.025 0.0494
Entamoeba histolytica PH domain containing protein kinase, putative 0.026 0.3804 0.7662
Echinococcus granulosus cytochrome P450 2K1 0.0024 0.027 0.027
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.1344 0.2708
Onchocerca volvulus Putative zinc finger protein 0.0013 0.0097 0.2204
Brugia malayi Variant SH3 domain containing protein 0.0013 0.0097 0.0196
Trichomonas vaginalis AGC family protein kinase 0.0338 0.4963 1
Trypanosoma cruzi hypothetical protein 0.0013 0.0097 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0086 0.0174
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0086 0.0174
Brugia malayi AMP-binding enzyme family protein 0.0023 0.025 0.0504
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Onchocerca volvulus 0.0012 0.0086 0.194
Echinococcus multilocularis protein patched 0.0041 0.0522 0.0522
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0247 0.361 1
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0325 0.4769 0.9609
Echinococcus multilocularis smad 0.0008 0.0022 0.0022
Echinococcus multilocularis cpg binding protein 0.0037 0.0453 0.0453
Schistosoma mansoni atypical protein kinase C 0.0113 0.1598 0.1598
Entamoeba histolytica PH domain containing protein kinase, putative 0.023 0.3346 0.6738
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0005 0.0005
Mycobacterium leprae putative cytochrome p450 0.0024 0.027 0.2544
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0013 0.0097 0.0097
Echinococcus granulosus oxysterol binding protein 1 0.0013 0.0097 0.0097
Loa Loa (eye worm) Plekhf2 protein 0.0013 0.0097 0.0196
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Echinococcus granulosus serine:threonine protein kinase N2 0.0113 0.1598 0.1598
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0212 0.3074 0.3074
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.001 0.0057 0.0495
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0005 0.001
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0247 0.361 0.361
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0086 0.0086
Brugia malayi PH domain containing protein 0.0013 0.0097 0.0196
Entamoeba histolytica hypothetical protein 0.0018 0.0175 0.0343
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0018 0.0175 0.0343
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0024 0.027 0.3371
Echinococcus multilocularis pleckstrin y domain containing family A 0.0013 0.0097 0.0097
Echinococcus multilocularis cytohesin 1 0.0013 0.0097 0.0097
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0018 0.0175 0.0471
Schistosoma mansoni ferritin 0.001 0.0057 0.0057
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0086 0.0086
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0242 0.3532 0.3532
Brugia malayi Cytochrome P450 family protein 0.0042 0.0529 0.1066
Echinococcus multilocularis serine:threonine protein kinase N2 0.0113 0.1598 0.1598
Schistosoma mansoni cpg binding protein 0.0035 0.0423 0.0423
Echinococcus granulosus GRB2 associated binding protein 3 0.0013 0.0097 0.0097
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0086 0.0086
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0148 0.182
Trichomonas vaginalis AGC family protein kinase 0.0113 0.1598 0.3213
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0022 0.0022
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0522 0.0522
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.1048 1
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0163 0.0437
Leishmania major protein kinase A catalytic subunit 0.0247 0.361 1
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0298 0.2805
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0086 0.0174
Echinococcus multilocularis pdz domain containing protein 0.0013 0.0097 0.0097
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0522 0.0522
Echinococcus multilocularis Pleckstrin y 0.0013 0.0097 0.0097
Echinococcus granulosus protein kinase c iota type 0.0113 0.1598 0.1598
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0247 0.361 0.361
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0174
Schistosoma mansoni serine/threonine-protein kinase 0.023 0.3346 0.3346
Brugia malayi PH domain containing protein 0.0013 0.0097 0.0196
Entamoeba histolytica hypothetical protein 0.0018 0.0175 0.0343
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Loa Loa (eye worm) PH domain-containing protein 0.0013 0.0097 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.1598 0.1598
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0086 0.0174
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0113 0.1598 0.1598
Echinococcus granulosus cpg binding protein 0.0037 0.0453 0.0453
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0013 0.0097 0.0196
Brugia malayi PH domain containing protein 0.0013 0.0097 0.0196
Echinococcus multilocularis nervana 2 0.0212 0.3074 0.3074
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.018 0.2607 0.5253
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0013 0.0097 0.0196
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0086 0.0086
Trypanosoma cruzi PH domain containing protein, putative 0.0013 0.0097 0.0256
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0792 0.0792
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.001 0.0057 0.0656
Loa Loa (eye worm) hypothetical protein 0.0023 0.025 0.0504
Brugia malayi nuclear hormone receptor 0.0012 0.0086 0.0174
Loa Loa (eye worm) hypothetical protein 0.0081 0.1112 0.224
Schistosoma mansoni ferritin light chain 0.001 0.0057 0.0057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0021 0.0032
Trichomonas vaginalis kinesin light chain, putative 0.0013 0.0097 0.0186
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0653 0.824
Trichomonas vaginalis rotamase, putative 0.0032 0.0381 0.0757
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0522 0.0522
Entamoeba histolytica protein kinase, putative 0.0325 0.4769 0.9609
Trypanosoma cruzi rac serine-threonine kinase, putative 0.023 0.3346 0.9267
Brugia malayi Cadps2 protein 0.0013 0.0097 0.0196
Brugia malayi cytochrome P450 0.0024 0.027 0.0545
Schistosoma mansoni hypothetical protein 0.0013 0.0097 0.0097
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0018 0.0175 0.0471
Schistosoma mansoni rho gtpase activating protein 0.0013 0.0097 0.0097
Trypanosoma cruzi PH domain containing protein, putative 0.0013 0.0097 0.0256
Trichomonas vaginalis AGC family protein kinase 0.0338 0.4963 1
Brugia malayi protein kinase C II. 0.0113 0.1598 0.3221
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.1344 0.1344
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.025 0.2351
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0024 0.027 0.2544
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.1048 0.2188
Echinococcus multilocularis Smad4 0.0008 0.0022 0.0022
Echinococcus multilocularis rac serine:threonine kinase 0.023 0.3346 0.3346
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0013 0.0097 0.0097
Mycobacterium ulcerans bacterioferritin BfrB 0.001 0.0057 0.0495
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0013 0.0097 0.0186
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0731 0.1473
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0013 0.0097 0.0097
Schistosoma mansoni apoferritin-2 0.001 0.0057 0.0057
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0381 0.1041
Toxoplasma gondii AGC kinase 0.0247 0.361 0.7566
Echinococcus granulosus dynamin 1 0.0013 0.0097 0.0097
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0024 0.027 0.0535
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0013 0.0097 0.0196
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0247 0.361 0.7566
Schistosoma mansoni serine/threonine-protein kinase 0.023 0.3346 0.3346
Brugia malayi Protein kinase domain containing protein 0.0113 0.1598 0.3221
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.027 0.0736
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0792 0.2182
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.1962 0.1962
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0113 0.1598 0.1598
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0522 0.1051
Schistosoma mansoni zinc finger protein 0.0013 0.0097 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0024 0.027 0.3371
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0247 0.361 0.361
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Echinococcus granulosus Pleckstrin y 0.0013 0.0097 0.0097
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0013 0.0097 0.0196
Entamoeba histolytica protein kinase, putative 0.0338 0.4963 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0217 0.3152 0.3152
Echinococcus multilocularis serine:threonine protein kinase N2 0.0113 0.1598 0.1598
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0018 0.0175 0.0471
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0022 0.0022
Toxoplasma gondii AGC kinase 0.0325 0.4769 1
Schistosoma mansoni dynamin 0.0013 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.004 0.0499 0.0499
Brugia malayi Probable ClpP-like protease 0.0076 0.1048 0.2111
Echinococcus granulosus myotubularin protein 13 0.0013 0.0097 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0021 0.0032
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0097 0.0256
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.001 0.0057 0.0049
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.1344 0.1344
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0148 0.182
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0086 0.194
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0174
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Echinococcus granulosus nervana 2 0.0212 0.3074 0.3074
Loa Loa (eye worm) Smad1 0.0008 0.0022 0.0045
Entamoeba histolytica hypothetical protein 0.0013 0.0097 0.0186
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.025 0.068
Echinococcus granulosus beta 1 syntrophin 0.0013 0.0097 0.0097
Echinococcus multilocularis expressed protein 0.0033 0.0392 0.0392
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0212 0.3074 0.3074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0086 0.0174
Toxoplasma gondii hypothetical protein 0.0026 0.0298 0.0614
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.025 0.3115
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0021 0.0032
Echinococcus multilocularis protein kinase c iota type 0.0113 0.1598 0.1598
Loa Loa (eye worm) AGC/AKT protein kinase 0.0338 0.4963 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.004 0.0499 0.0499
Echinococcus multilocularis muscleblind protein 1 0.018 0.2607 0.2607
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0022 0.0022
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0247 0.361 0.361
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0013 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0023 0.025 0.0504
Brugia malayi CHE-14 protein 0.0041 0.0522 0.1051
Trypanosoma cruzi hypothetical protein 0.0013 0.0097 0.0256
Schistosoma mansoni hypothetical protein 0.0013 0.0097 0.0097
Entamoeba histolytica PH domain containing protein kinase, putative 0.023 0.3346 0.6738
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Loa Loa (eye worm) hypothetical protein 0.018 0.2607 0.5253
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0163 0.151
Loa Loa (eye worm) CYP4Cod1 0.0042 0.0529 0.1066
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.1048 1
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Echinococcus multilocularis DCC interacting protein 13 beta 0.0013 0.0097 0.0097
Trichomonas vaginalis protein transport protein sec7, putative 0.0013 0.0097 0.0186
Onchocerca volvulus outspread protein homolog 0.0013 0.0097 0.2204
Brugia malayi Cytohesin 3 0.0013 0.0097 0.0196
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0024 0.027 0.2544
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.1048 0.2892
Echinococcus granulosus Protein kinase C brain isozyme 0.0113 0.1598 0.1598
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0032 0.0032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0792 0.7546
Loa Loa (eye worm) hypothetical protein 0.0017 0.0163 0.0328
Echinococcus multilocularis Rho GTPase activating protein 24 0.0013 0.0097 0.0097
Brugia malayi MH2 domain containing protein 0.0008 0.0022 0.0045
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0024 0.027 0.2544
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.001
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0013 0.0097 0.0256
Loa Loa (eye worm) rho-GTPase-activating 0.0013 0.0097 0.0196
Echinococcus granulosus nervana 2 0.0212 0.3074 0.3074
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.1962 0.1962
Echinococcus granulosus Pleckstrin y 0.0013 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0017 0.0163 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0731 0.0731
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0086 0.0086
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0013 0.0097 0.0097
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0052 0.013
Brugia malayi Hr1 repeat family protein 0.0113 0.1598 0.3221
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0247 0.361 0.7273
Echinococcus multilocularis dynamin 1 0.0013 0.0097 0.0097
Trypanosoma brucei cytochrome P450, putative 0.0042 0.0529 0.1057
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0024 0.027 0.2544
Echinococcus granulosus calcium dependent secretion activator 1 0.0013 0.0097 0.0097
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0731 0.0731
Toxoplasma gondii AtPH1 family protein 0.0013 0.0097 0.0193
Brugia malayi PH domain containing protein 0.0013 0.0097 0.0196
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0086 0.0086
Trypanosoma cruzi Protein kinase B 0.023 0.3346 0.9267
Toxoplasma gondii hypothetical protein 0.0013 0.0097 0.0193
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0217 0.3152 0.8729
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0013 0.0097 0.0097
Leishmania major serine/threonine-protein kinase a, putative 0.0018 0.0175 0.0471
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0086 0.0086
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0792 0.7546
Schistosoma mansoni myotubularin-related protein 0.0013 0.0097 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Entamoeba histolytica hypothetical protein 0.0013 0.0097 0.0186
Echinococcus multilocularis Pleckstrin y 0.0013 0.0097 0.0097
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0242 0.3532 0.3532
Trichomonas vaginalis centaurin beta, putative 0.0013 0.0097 0.0186
Trypanosoma cruzi hypothetical protein 0.0013 0.0097 0.0256
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0247 0.361 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0032 0.0032
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0113 0.1598 0.3221
Loa Loa (eye worm) hypothetical protein 0.0041 0.0522 0.1051
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0086 0.0086
Echinococcus multilocularis Glutaredoxin protein 5 0.0212 0.3074 0.3074
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0024 0.027 0.2544
Schistosoma mansoni hypothetical protein 0.004 0.0499 0.0499
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0052 0.0094
Brugia malayi ecdysteroid receptor 0.0012 0.0086 0.0174
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0381 0.1041
Brugia malayi Muscleblind-like protein 0.018 0.2607 0.5253
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0024 0.027 0.3371
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0018 0.0175 0.0471
Trichomonas vaginalis AGC family protein kinase 0.0113 0.1598 0.3213
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0032
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0018 0.0175 0.0471
Brugia malayi CXXC zinc finger family protein 0.0035 0.0423 0.0853
Brugia malayi Plekhf2 protein 0.0013 0.0097 0.0196
Echinococcus granulosus protein kinase c epsilon type 0.0113 0.1598 0.1598
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.027 0.2544
Onchocerca volvulus 0.0013 0.0097 0.2204
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.025 0.2351
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0731 0.0731
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0247 0.361 1
Echinococcus multilocularis Oxysterol binding protein 11 0.0013 0.0097 0.0097
Echinococcus multilocularis 0.0024 0.027 0.027
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0086 0.0174
Schistosoma mansoni syntrophin 0.0013 0.0097 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0086 0.0174
Echinococcus multilocularis expressed protein 0.001 0.0057 0.0057
Brugia malayi Smad1 0.0008 0.0022 0.0045
Schistosoma mansoni patched 1 0.0041 0.0522 0.0522
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0013 0.0097 0.0186
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Trypanosoma cruzi NIMA-related kinase, putative 0.0018 0.0175 0.0471
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0024 0.027 0.3371
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0024 0.027 0.3371
Echinococcus granulosus Smad4 0.0008 0.0022 0.0022
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0086 0.0086
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.025 0.2351
Leishmania major cytochrome p450-like protein 0.0024 0.027 0.0736
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0013 0.0097 0.0186
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0024 0.027 0.2544
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0086 0.0086
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0247 0.361 0.361
Brugia malayi MH1 domain containing protein 0.0008 0.0022 0.0045
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0024 0.027 0.2544
Schistosoma mansoni hypothetical protein 0.0024 0.027 0.027
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0013 0.0097 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0086 0.0174
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0086 0.0086
Echinococcus granulosus protein kinase C gamma type 0.0113 0.1598 0.1598
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.001
Mycobacterium tuberculosis Bacterioferritin BfrB 0.001 0.0057 0.0656
Brugia malayi PH domain containing protein 0.0013 0.0097 0.0196
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0005 0.001
Entamoeba histolytica protein kinase, putative 0.0018 0.0175 0.0343
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0097 0.0186
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.001
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.1048 1
Trichomonas vaginalis hypothetical protein 0.0013 0.0097 0.0186
Brugia malayi MAX-1A 0.0013 0.0097 0.0196
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Schistosoma mansoni centaurin alpha 0.0013 0.0097 0.0097
Onchocerca volvulus 0.0013 0.0097 0.2204
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Schistosoma mansoni ferritin light chain 0.001 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0174
Trichomonas vaginalis centaurin/arf, putative 0.0013 0.0097 0.0186
Toxoplasma gondii hypothetical protein 0.0013 0.0097 0.0193
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0013 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Leishmania major protein kinase A catalytic subunit isoform 1 0.0247 0.361 1
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0013 0.0097 0.0097
Leishmania major protein kinase, putative 0.0018 0.0175 0.0471
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Leishmania major protein kinase, putative 0.0018 0.0175 0.0471
Plasmodium falciparum PH domain-containing protein, putative 0.0013 0.0097 0.0256
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0013 0.0097 0.0256
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0013 0.0097 0.2204
Echinococcus granulosus serine threonine protein kinase nrc 0.0217 0.3152 0.3152
Brugia malayi Oxysterol binding protein 0.0013 0.0097 0.0196
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0086 0.0086
Trichomonas vaginalis ferritin, putative 0.001 0.0057 0.0104
Loa Loa (eye worm) hypothetical protein 0.0017 0.0163 0.0328
Schistosoma mansoni zinc finger protein 0.0013 0.0097 0.0097
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0018 0.0175 0.0343
Echinococcus granulosus expressed conserved protein 0.009 0.1256 0.1256
Giardia lamblia Kinase, AGC PKA 0.0247 0.361 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.025 0.2351
Loa Loa (eye worm) oxidoreductase 0.0007 0.0005 0.001
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0018 0.0175 0.0343
Schistosoma mansoni cpg binding protein 0.0037 0.0453 0.0453
Brugia malayi Protein kinase domain containing protein 0.0113 0.1598 0.3221
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0024 0.027 0.2544
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.027 0.0736
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.165 0.3325
Brugia malayi Protein kinase domain containing protein 0.0338 0.4963 1
Loa Loa (eye worm) cytohesin 3 0.0013 0.0097 0.0196
Loa Loa (eye worm) hypothetical protein 0.0113 0.1598 0.3221
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.361 0.361
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Echinococcus multilocularis ferritin 0.001 0.0057 0.0057
Brugia malayi Dynamin 0.0013 0.0097 0.0196
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0086 0.0086
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.1344 0.27
Echinococcus granulosus expressed protein 0.001 0.0057 0.0057
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0013 0.0097 0.0097
Echinococcus granulosus expressed protein 0.0033 0.0392 0.0392
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.1598 0.1598
Loa Loa (eye worm) syntrophin-1 0.0013 0.0097 0.0196
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0064 0.0064
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0013 0.0097 0.0097
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.025 0.2351
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0731 0.0731
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0013 0.0097 0.0097
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0018 0.0175 0.0471
Trichomonas vaginalis centaurin alpha, putative 0.0013 0.0097 0.0186
Brugia malayi Oxysterol-binding protein 0.0013 0.0097 0.0196
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0032 0.0032
Brugia malayi Cytochrome P450 family protein 0.0024 0.027 0.0545
Loa Loa (eye worm) cytochrome P450 family protein 0.0042 0.0529 0.1066
Loa Loa (eye worm) uncoordinated protein 104 0.0013 0.0097 0.0196
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.025 0.2351
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0792 0.0792
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.1048 1
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0097 0.0256
Brugia malayi Cytochrome P450 family protein 0.0062 0.0839 0.169
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Entamoeba histolytica PH domain containing protein 0.0013 0.0097 0.0186
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0052 0.013
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0839 0.169
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0022 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0086 0.0174
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0113 0.1598 0.1598
Echinococcus multilocularis Ras associated and pleckstrin y 0.0013 0.0097 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0086 0.0174
Schistosoma mansoni goodpasture antigen-binding protein 0.0013 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0024 0.027 0.3371
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.1048 0.1048
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0086 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.1598 0.1598
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0247 0.361 0.361
Toxoplasma gondii phosphatidylinositol transfer protein 0.0013 0.0097 0.0193
Echinococcus granulosus Oxysterol binding protein 11 0.0013 0.0097 0.0097
Schistosoma mansoni dynamin 0.0013 0.0097 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Toxoplasma gondii cytochrome p450 superfamily protein 0.0024 0.027 0.0557
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.1598 0.1598
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0032
Echinococcus multilocularis oxysterol binding protein 3 0.0013 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0032
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0653 0.824
Brugia malayi hypothetical protein 0.0013 0.0097 0.0196
Onchocerca volvulus 0.0023 0.025 0.5862
Loa Loa (eye worm) hypothetical protein 0.0247 0.361 0.7273
Trichomonas vaginalis AGC family protein kinase 0.0247 0.361 0.727
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.1598 0.1598
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0086 0.0174
Trichomonas vaginalis AGC family protein kinase 0.0113 0.1598 0.3213
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0163 0.2
Trichomonas vaginalis AGC family protein kinase 0.0338 0.4963 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Brugia malayi MH2 domain containing protein 0.0008 0.0022 0.0045
Trichomonas vaginalis centaurin gamma, putative 0.0013 0.0097 0.0186
Echinococcus granulosus ferritin 0.001 0.0057 0.0057
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0024 0.027 0.2544
Trypanosoma cruzi cytochrome P450, putative 0.0042 0.0529 0.1453
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0081 0.1112 0.2232
Schistosoma mansoni rotamase 0.0033 0.0392 0.0392
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0097 0.0186
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0013 0.0097 0.0097
Brugia malayi PH domain containing protein 0.0013 0.0097 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0086 0.0174
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Entamoeba histolytica ARF GTPase activating protein, putative 0.0013 0.0097 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0032 0.0032
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0086 0.0086
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0381 0.1041
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0792 0.0792
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0174
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0174
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Trypanosoma brucei PH domain containing protein, putative 0.0013 0.0097 0.0186
Brugia malayi Pleckstrin Homology Domain 0.0013 0.0097 0.0196
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0024 0.027 0.3371
Entamoeba histolytica protein kinase, putative 0.0018 0.0175 0.0343
Brugia malayi MH1 domain containing protein 0.0008 0.0022 0.0045
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0013 0.0097 0.0256
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0013 0.0097 0.0186
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.1006 0.1006
Trypanosoma cruzi hypothetical protein 0.0013 0.0097 0.0256
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0042 0.0529 0.5025
Entamoeba histolytica PH domain containing protein 0.0013 0.0097 0.0186
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0005 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Trypanosoma cruzi cytochrome P450, putative 0.0042 0.0529 0.1453
Onchocerca volvulus 0.0013 0.0097 0.2204
Brugia malayi steroid hormone receptor 0.0012 0.0086 0.0174
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0013 0.0097 0.0256
Brugia malayi p70 ribosomal S6 kinase beta 0.0325 0.4769 0.9609
Brugia malayi AMP-binding enzyme family protein 0.0023 0.025 0.0504
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.025 0.2351
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Echinococcus multilocularis calcium dependent secretion activator 1 0.0013 0.0097 0.0097
Schistosoma mansoni oxysterol-binding protein 1 0.0013 0.0097 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0021 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Loa Loa (eye worm) oxysterol binding protein 0.0013 0.0097 0.0196
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0021 0.0032
Entamoeba histolytica hypothetical protein 0.0013 0.0097 0.0186
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0018 0.0175 0.0471
Echinococcus multilocularis protein kinase c epsilon type 0.0113 0.1598 0.1598
Brugia malayi Syntrophin-1 0.0013 0.0097 0.0196
Leishmania major cytochrome p450-like protein 0.0024 0.027 0.0736
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0013 0.0097 0.0196
Echinococcus multilocularis Pleckstrin y 0.0013 0.0097 0.0097
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0024 0.027 0.2544
Entamoeba histolytica protein kinase, putative 0.0018 0.0175 0.0343
Brugia malayi probable spectrin beta chain 0.0013 0.0097 0.0196
Brugia malayi AMP-binding enzyme family protein 0.0023 0.025 0.0504
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0013 0.0097 0.0186
Trichomonas vaginalis protein transport protein sec7, putative 0.0013 0.0097 0.0186
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0018 0.0175 0.0343
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Schistosoma mansoni hypothetical protein 0.0013 0.0097 0.0097
Entamoeba histolytica PH domain containing protein 0.0013 0.0097 0.0186
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0097 0.0186
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0086 0.0086
Mycobacterium ulcerans hypothetical protein 0.0023 0.025 0.2351
Echinococcus granulosus muscleblind protein 0.018 0.2607 0.2607
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0163 0.0437
Trichomonas vaginalis AGC family protein kinase 0.0338 0.4963 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0024 0.027 0.3371
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0018 0.0175 0.0471
Trypanosoma cruzi PH domain containing protein, putative 0.0013 0.0097 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Schistosoma mansoni ferritin 0.001 0.0057 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.361 0.361
Entamoeba histolytica hypothetical protein 0.0013 0.0097 0.0186
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.1048 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Brugia malayi Dynamin 0.0013 0.0097 0.0196
Echinococcus granulosus DCC interacting protein 13 beta 0.0013 0.0097 0.0097
Loa Loa (eye worm) cytochrome P450 0.0024 0.027 0.0545
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0086 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0247 0.361 1
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0064 0.0129
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0018 0.0175 0.0343
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0086 0.0086
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0217 0.3152 0.8729
Schistosoma mansoni goodpasture antigen-binding protein 0.0013 0.0097 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0024 0.027 0.3371
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0018 0.0175 0.0356
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0298 0.243
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0013 0.0097 0.0186
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0298 0.0811
Entamoeba histolytica p21-activated kinase 0.0018 0.0175 0.0343
Echinococcus granulosus Rho GTPase activating protein 24 0.0013 0.0097 0.0097
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0653 0.0653
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0792 0.1651
Trichomonas vaginalis rotamase, putative 0.0033 0.0392 0.078
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0062 0.0125
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0731 0.0731
Echinococcus granulosus smad 0.0008 0.0022 0.0022
Echinococcus multilocularis oxysterol binding protein 1 0.0013 0.0097 0.0097
Trypanosoma cruzi hypothetical protein 0.0013 0.0097 0.0256
Entamoeba histolytica protein kinase, putative 0.0338 0.4963 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Schistosoma mansoni apoferritin-2 0.001 0.0057 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0086 0.0086
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.025 0.068
Entamoeba histolytica PH domain containing protein kinase, putative 0.0018 0.0175 0.0343
Loa Loa (eye worm) hypothetical protein 0.0076 0.1048 0.2111
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0005 0.0005
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.1366 0.1366
Trypanosoma brucei rac serine-threonine kinase, putative 0.0338 0.4963 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0381 0.0757
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0086 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0024 0.027 0.3371
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0113 0.1598 0.3221
Echinococcus granulosus oxysterol binding protein 9 0.0013 0.0097 0.0097
Brugia malayi nuclear receptor NHR-88 0.0012 0.0086 0.0174
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0217 0.3152 0.8729
Plasmodium falciparum calcium-dependent protein kinase 7 0.0018 0.0175 0.0471
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0081 0.1112 0.2232
Brugia malayi Variant SH3 domain containing protein 0.0013 0.0097 0.0196
Entamoeba histolytica protein kinase, putative 0.0018 0.0175 0.0343
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0381 0.0757
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Schistosoma mansoni smad1 5 8 and 0.0008 0.0022 0.0022
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0247 0.361 0.727
Schistosoma mansoni ferritin 0.001 0.0057 0.0057
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0024 0.027 0.2544
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0013 0.0097 0.0097
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.1048 1
Plasmodium falciparum oxysterol-binding protein, putative 0.0013 0.0097 0.0256
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0013 0.0097 0.0097
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0113 0.1598 0.1598
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0174
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0086 0.194
Echinococcus multilocularis oxysterol binding protein 9 0.0013 0.0097 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0024 0.027 0.3371
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0024 0.027 0.3371
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0024 0.027 0.2544
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0113 0.1598 0.1598
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0024 0.027 0.3371
Echinococcus granulosus oxysterol binding protein 3 0.0013 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Schistosoma mansoni hypothetical protein 0.004 0.0499 0.0499
Toxoplasma gondii protein kinase domain-containing protein 0.0018 0.0175 0.0356
Leishmania major folate/biopterin transporter, putative 0.0018 0.0175 0.0471
Echinococcus multilocularis serine threonine protein kinase 0.0113 0.1598 0.1598
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0731 0.0731
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0381 0.0788
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0792 0.0792
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0024 0.027 0.3371
Echinococcus multilocularis GRB2 associated binding protein 3 0.0013 0.0097 0.0097
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0247 0.361 1
Trypanosoma cruzi PH domain containing protein, putative 0.0013 0.0097 0.0256
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0024 0.027 0.3371
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0731 0.0731
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0032
Toxoplasma gondii AGC kinase 0.0247 0.361 0.7566
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0013 0.0097 0.0097
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0392 0.079
Brugia malayi PH domain containing protein 0.0013 0.0097 0.0196
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.1048 0.1048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0086 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0086 0.0174
Entamoeba histolytica PH domain containing protein kinase, putative 0.026 0.3804 0.7662
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0086 0.0174
Echinococcus granulosus Pleckstrin y 0.0013 0.0097 0.0097
Toxoplasma gondii Oxysterol-binding protein 0.0013 0.0097 0.0193
Echinococcus granulosus NDR protein kinase 0.0113 0.1598 0.1598
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0086 0.0086
Trichomonas vaginalis alpha chimerin, putative 0.0013 0.0097 0.0186
Echinococcus multilocularis beta 1 syntrophin 0.0013 0.0097 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0086 0.0174
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.1048 1
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0024 0.027 0.2544
Entamoeba histolytica PH domain containing protein kinase, putative 0.0018 0.0175 0.0343
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0024 0.027 0.3371
Echinococcus multilocularis expressed conserved protein 0.009 0.1256 0.1256
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0052 0.0098
Echinococcus multilocularis microtubule associated protein 2 0.0674 1 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0423 0.0853
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0013 0.0097 0.0256
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0024 0.027 0.2544
Entamoeba histolytica hypothetical protein 0.0013 0.0097 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Schistosoma mansoni microtubule-associated protein tau 0.0674 1 1
Schistosoma mansoni hypothetical protein 0.0013 0.0097 0.0097
Leishmania major hypothetical protein, conserved 0.0013 0.0097 0.0256
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0298 0.0811
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0086 0.0086
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0086 0.194
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0174
Onchocerca volvulus 0.0013 0.0097 0.2204
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0792 0.7546
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0086 0.0086
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0018 0.0175 0.0471
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0024 0.027 0.0736
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0113 0.1598 0.1598
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0086 0.0086
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0108 0.1521 0.3057
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0086 0.0086
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0013 0.0097 0.2204
Onchocerca volvulus 0.0035 0.0423 1
Leishmania major protein kinase A catalytic subunit isoform 2 0.0247 0.361 1
Trichomonas vaginalis AGC family protein kinase 0.0338 0.4963 1
Echinococcus multilocularis myotubularin protein 13 0.0013 0.0097 0.0097
Trichomonas vaginalis centaurin/arf, putative 0.0013 0.0097 0.0186
Schistosoma mansoni hypothetical protein 0.0013 0.0097 0.0097
Entamoeba histolytica protein kinase, putative 0.0113 0.1598 0.3213
Loa Loa (eye worm) hypothetical protein 0.0013 0.0097 0.0196
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0888 0.1854
Schistosoma mansoni serine/threonine kinase 0.0113 0.1598 0.1598
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0392 0.079
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0086 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0392 0.078
Brugia malayi Uncoordinated protein 104 0.0013 0.0097 0.0196
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0024 0.027 0.2544
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0024 0.027 0.3371
Loa Loa (eye worm) AGC/PKA protein kinase 0.0247 0.361 0.7273
Echinococcus multilocularis protein dispatched 1 0.0047 0.0609 0.0609
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0174
Echinococcus multilocularis serine:threonine protein kinase 38 0.0113 0.1598 0.1598
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0217 0.3152 0.3152
Echinococcus granulosus Glutaredoxin protein 5 0.0212 0.3074 0.3074
Echinococcus granulosus pdz domain containing protein 0.0013 0.0097 0.0097
Loa Loa (eye worm) AGC/NDR protein kinase 0.0113 0.1598 0.3221
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0086 0.0086
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0247 0.361 0.361
Mycobacterium ulcerans bacterioferritin BfrA 0.001 0.0057 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0097 0.0186
Brugia malayi PH domain containing protein 0.0013 0.0097 0.0196
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0148 0.182
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0005 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.1598 0.1598
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0024 0.027 0.2544
Trypanosoma cruzi hypothetical protein 0.0013 0.0097 0.0256
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0024 0.027 0.3371
Schistosoma mansoni cpg binding protein 0.0037 0.0453 0.0453
Leishmania major hypothetical protein, conserved 0.0013 0.0097 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0021 0.0032
Plasmodium vivax PH domain containing protein 0.0013 0.0097 0.0256
Entamoeba histolytica protein kinase 2, putative 0.0217 0.3152 0.6347
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0024 0.027 0.2544
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0175 0.0343

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 64.548 uM PUBCHEM_BIOASSAY: TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 56.2341 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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