Detailed information for compound 1407491

Basic information

Technical information
  • TDR Targets ID: 1407491
  • Name: 4-chloro-8-methoxy-2-methyl-3-prop-2-enylquin oline
  • MW: 247.72 | Formula: C14H14ClNO
  • H donors: 0 H acceptors: 1 LogP: 4.26 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCc1c(C)nc2c(c1Cl)cccc2OC
  • InChi: 1S/C14H14ClNO/c1-4-6-10-9(2)16-14-11(13(10)15)7-5-8-12(14)17-3/h4-5,7-8H,1,6H2,2-3H3
  • InChiKey: QRBNWZQTUZHPEF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-Allyl-4-chloro-8-methoxy-2-methyl-quinoline
  • 3-allyl-4-chloro-8-methoxy-2-methylquinoline
  • 4-chloro-8-methoxy-2-methyl-3-prop-2-enyl-quinoline
  • MLS000687666
  • SMR000283445
  • Oprea1_791815
  • ZINC00050685
  • BAS 00333829
  • ChemDiv2_002161
  • A0933/0043708
  • Oprea1_086308

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens chromobox homolog 1 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_129545 All targets in OG5_129545
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Chromobox protein homolog 5, putative Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Heterochromatin protein 1 homolog Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0094 0.0062 0.0059
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0111 0.012 0.0115
Entamoeba histolytica protein kinase, putative 0.0141 0.0226 0.0226
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0327 0.0875 0.0857
Echinococcus multilocularis mitogen activated protein kinase 3 0.0169 0.0323 0.0304
Brugia malayi p70 ribosomal S6 kinase beta 0.0593 0.1803 0.179
Echinococcus granulosus tyrosine protein kinase Src42A 0.0192 0.0401 0.0382
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0108 0.011 0.0596
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0114 0.013 0.0128
Brugia malayi C1-like domain containing protein 0.0382 0.1066 0.1053
Schistosoma mansoni growth factor receptor-bound protein 0.0124 0.0164 0.0161
Entamoeba histolytica PH domain containing protein kinase, putative 0.0202 0.0436 0.0436
Onchocerca volvulus 0.0323 0.086 0.0834
Trypanosoma cruzi cdc2-related kinase 3 0.0246 0.0589 0.0587
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Loa Loa (eye worm) hypothetical protein 0.0124 0.0164 0.0159
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0304 0.0792 0.0774
Echinococcus multilocularis NCK adaptor protein 0.0124 0.0164 0.0145
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0135 0.0204 0.0202
Entamoeba histolytica protein kinase, putative 0.0325 0.0865 0.0865
Onchocerca volvulus Tyrosine kinase homolog 0.1168 0.3809 0.3791
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0114 0.013 0.0128
Onchocerca volvulus 0.0118 0.0144 0.0116
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0164 0.0306 0.0287
Echinococcus multilocularis chromobox protein 1 0.0084 0.0026 0.0006
Giardia lamblia Kinase, CMGC CK2 0.0205 0.0448 0.0445
Plasmodium falciparum serine/threonine protein kinase 0.0111 0.012 0.1344
Trichomonas vaginalis AGC family protein kinase 0.0346 0.0939 0.0937
Echinococcus granulosus fibroblast growth factor receptor 4 0.0507 0.1502 0.1485
Echinococcus granulosus tyrosine protein kinase Srms 0.014 0.0222 0.0203
Schistosoma mansoni tyrosine kinase 0.0776 0.2439 0.2437
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0246 0.0589 0.0587
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0327 0.0875 0.0857
Echinococcus multilocularis 0.0184 0.0374 0.0355
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0327 0.0875 0.0857
Loa Loa (eye worm) hypothetical protein 0.0082 0.0019 0.0014
Brugia malayi Protein kinase domain containing protein 0.0418 0.1191 0.1178
Loa Loa (eye worm) hypothetical protein 0.0165 0.0308 0.0302
Echinococcus multilocularis tyrosine protein kinase Srms 0.0268 0.0667 0.0649
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.049 0.1442 0.1425
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0143 0.0232 0.0227
Plasmodium vivax protein kinase, putative 0.0098 0.0073 0.0804
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0387 0.0384
Echinococcus granulosus protein kinase c epsilon type 0.041 0.1161 0.1144
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.3149 0.3136
Echinococcus granulosus c src tyrosine kinase 0.02 0.043 0.0411
Echinococcus multilocularis cyclin dependent kinase 1 0.0246 0.0589 0.0571
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.1165 0.1163
Schistosoma mansoni tyrosine kinase 0.0951 0.305 0.3049
Echinococcus multilocularis mitogen activated protein kinase 11 0.0333 0.0895 0.0877
Onchocerca volvulus 0.0118 0.0144 0.0116
Echinococcus granulosus titin 0.0106 0.0101 0.0082
Echinococcus granulosus rho-associated protein kinase 1 0.0694 0.2154 0.2139
Echinococcus granulosus tyrosine protein kinase ABL1 0.0591 0.1795 0.1779
Schistosoma mansoni protein kinase 0.0473 0.1383 0.1381
Schistosoma mansoni hypothetical protein 0.0175 0.0344 0.0341
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0188 0.0387 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0496 0.1462 0.146
Toxoplasma gondii AGC kinase 0.0593 0.1803 1
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Plasmodium falciparum serine/threonine protein kinase, putative 0.0304 0.0792 0.9033
Echinococcus multilocularis casein kinase ii subunit alpha 0.0205 0.0448 0.0429
Echinococcus multilocularis tyrosine kinase 0.014 0.0222 0.0203
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0302 0.0787 0.0769
Loa Loa (eye worm) AUR protein kinase 0.0304 0.0792 0.0787
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0164 0.0306 0.0303
Leishmania major protein kinase, putative 0.0304 0.0792 0.0789
Echinococcus multilocularis roundabout 2 0.0086 0.0034 0.0014
Onchocerca volvulus 0.0635 0.1948 0.1925
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0414 0.0411
Onchocerca volvulus 0.0241 0.0573 0.0546
Echinococcus multilocularis raf serine:threonine protein kinase 0.0158 0.0285 0.0266
Echinococcus granulosus protein kinase shaggy 0.0267 0.0664 0.0646
Trichomonas vaginalis AGC family protein kinase 0.0607 0.1852 0.185
Giardia lamblia Kinase, CDC7 0.0118 0.0144 0.0142
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.013 0.0128
Entamoeba histolytica serine/threonine protein kinase, putative 0.0077 0.0003 0.0003
Leishmania major protein kinase, putative 0.0108 0.011 0.0107
Schistosoma mansoni ephrin receptor 0.0215 0.0484 0.0481
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0141 0.0226 0.0206
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0195 0.0414 0.0395
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0171 0.033 0.0328
Echinococcus multilocularis tyrosine protein kinase Blk 0.0268 0.0667 0.0649
Echinococcus granulosus tyrosine protein kinase Fyn 0.0327 0.0875 0.0857
Loa Loa (eye worm) hypothetical protein 0.0085 0.0029 0.0024
Brugia malayi Protein kinase domain containing protein 0.014 0.0222 0.0207
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0327 0.0875 0.0857
Entamoeba histolytica cell division protein kinase 2, putative 0.0246 0.0589 0.0589
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0302 0.0787 0.0769
Schistosoma mansoni protein kinase 0.0184 0.0374 0.0371
Echinococcus multilocularis 0.0377 0.1049 0.1032
Trichomonas vaginalis CMGC family protein kinase 0.0205 0.0448 0.0445
Trichomonas vaginalis CMGC family protein kinase 0.0246 0.0589 0.0587
Echinococcus granulosus Glutaredoxin protein 5 0.0269 0.067 0.0652
Schistosoma mansoni nck2/grb4 0.0124 0.0164 0.0161
Leishmania major protein kinase A catalytic subunit 0.0188 0.0387 0.0384
Loa Loa (eye worm) TK/EGFR protein kinase 0.1304 0.4283 0.428
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Entamoeba histolytica diacylglycerol kinase, putative 0.0082 0.0019 0.0019
Entamoeba histolytica protein kinase domain containing protein 0.0205 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.0312 0.0821 0.0816
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0387 0.0384
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0111 0.012 0.0117
Trypanosoma cruzi cdc2-related kinase 3 0.0246 0.0589 0.0587
Echinococcus multilocularis Glutaredoxin protein 5 0.0269 0.067 0.0652
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0143 0.0232 0.023
Echinococcus granulosus dual specificity 0.0253 0.0615 0.0597
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0327 0.0875 0.0857
Loa Loa (eye worm) hypothetical protein 0.0259 0.0635 0.0629
Brugia malayi Doublecortin family protein 0.0181 0.0366 0.0351
Echinococcus multilocularis Immunoglobulin 0.0164 0.0306 0.0287
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.013 0.0128
Echinococcus multilocularis myosin iiia 0.0171 0.033 0.0311
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.011 0.0107
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0106 0.0103 0.0097
Echinococcus multilocularis Immunoglobulin 0.0164 0.0306 0.0287
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0418 0.1191 0.1186
Loa Loa (eye worm) hypothetical protein 0.0626 0.1917 0.1913
Schistosoma mansoni protein kinase 0.0127 0.0176 0.0174
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Trypanosoma cruzi casein kinase, putative 0.0181 0.0363 0.036
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0267 0.0664 0.0662
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0135 0.0204 0.0202
Plasmodium falciparum calcium-dependent protein kinase 2 0.0108 0.011 0.1228
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0648 0.1994 0.1989
Loa Loa (eye worm) hypothetical protein 0.0194 0.0409 0.0404
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0108 0.011 0.1228
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0246 0.0589 0.0584
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0268 0.0667 0.0649
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0109 0.0113 0.061
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0108 0.011 0.0091
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0086 0.0034 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Echinococcus granulosus roundabout 2 0.0086 0.0034 0.0014
Entamoeba histolytica protein kinase, putative 0.0204 0.0443 0.0443
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0507 0.1502 0.1485
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0267 0.0664 0.0646
Loa Loa (eye worm) AGC/PKA protein kinase 0.0188 0.0387 0.0382
Giardia lamblia Kinase, STE STE20 0.0171 0.033 0.0328
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0235 0.0554 0.0549
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0253 0.0615 0.0613
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0184 0.0376 0.0373
Brugia malayi hypothetical protein 0.0175 0.0342 0.0327
Echinococcus granulosus Vam6:Vps39 protein 0.0128 0.018 0.0161
Schistosoma mansoni tyrosine kinase 0.0776 0.2439 0.2437
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0306 0.0304
Mycobacterium ulcerans hypothetical protein 0.0106 0.0101 0.5
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0325 0.0865 0.0847
Echinococcus multilocularis dual specificity 0.0253 0.0615 0.0597
Echinococcus granulosus cGMP dependent protein kinase 0.0165 0.0307 0.0288
Brugia malayi MAP kinase sur-1 0.0169 0.0323 0.0309
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0473 0.1383 0.1367
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0144 0.0142
Leishmania major protein kinase, putative 0.0184 0.0376 0.0373
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0108 0.011 0.0596
Trypanosoma brucei aurora B kinase 0.0304 0.0792 0.0789
Trichomonas vaginalis STE family protein kinase 0.0127 0.0176 0.0174
Echinococcus multilocularis casein kinase i 0.0181 0.0363 0.0344
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0086 0.0034 0.0028
Brugia malayi SH2 domain containing protein 0.014 0.0222 0.0207
Entamoeba histolytica hypothetical protein 0.0395 0.111 0.111
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0184 0.0376 0.037
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0086 0.0034 0.0031
Schistosoma mansoni diacylglycerol kinase theta 0.0082 0.0019 0.0017
Brugia malayi Protein kinase domain containing protein 0.0346 0.0939 0.0925
Entamoeba histolytica protein kinase domain containing protein 0.0267 0.0664 0.0664
Schistosoma mansoni tyrosine kinase 0.0327 0.0875 0.0872
Brugia malayi Pleckstrin Homology Domain 0.0096 0.0069 0.0054
Echinococcus multilocularis PAK box P21 Rho binding 0.0127 0.0176 0.0157
Schistosoma mansoni protein kinase 0.0312 0.0822 0.0819
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0135 0.0204 0.0202
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0188 0.0387 0.44
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0411 0.1165 0.1148
Loa Loa (eye worm) hypothetical protein 0.0128 0.018 0.0175
Trichomonas vaginalis STE family protein kinase 0.0174 0.0341 0.0338
Plasmodium falciparum calcium-dependent protein kinase 5 0.0108 0.011 0.1228
Brugia malayi Protein kinase domain containing protein 0.0164 0.0306 0.0292
Brugia malayi hypothetical protein 0.014 0.0222 0.0207
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Entamoeba histolytica protein kinase, putative 0.0111 0.012 0.012
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0253 0.0616 0.0598
Giardia lamblia Kinase, CMGC MAPK 0.0169 0.0323 0.0321
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0026 0.0023
Schistosoma mansoni neuroglian 0.0086 0.0034 0.0031
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0184 0.0376 0.0373
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0235 0.0553 0.0535
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Trichomonas vaginalis AGC family protein kinase 0.036 0.0988 0.0986
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Plasmodium vivax glycogen synthase kinase 3, putative 0.0267 0.0664 0.7573
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Echinococcus multilocularis neuroglian 0.0201 0.0433 0.0414
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0174 0.0341 0.0322
Trypanosoma cruzi casein kinase II, putative 0.0205 0.0448 0.0445
Giardia lamblia Kinase, CMGC CLK 0.0184 0.0376 0.0373
Giardia lamblia Kinase, AGC PKA 0.0328 0.0876 0.0874
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0283 0.0721 0.8222
Loa Loa (eye worm) hypothetical protein 0.0175 0.0342 0.0336
Schistosoma mansoni cell adhesion molecule 0.0086 0.0034 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0323 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.012 0.0117
Echinococcus multilocularis titin 0.0106 0.0101 0.0082
Loa Loa (eye worm) hypothetical protein 0.0241 0.0573 0.0568
Echinococcus multilocularis cyclin dependent kinase 0.0246 0.0589 0.0571
Brugia malayi Protein kinase domain 0.0174 0.0341 0.0326
Schistosoma mansoni tyrosine kinase 0.0152 0.0264 0.0261
Echinococcus granulosus dual specificity 0.0114 0.013 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.143 0.4723 0.4722
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Plasmodium falciparum casein kinase 2, alpha subunit 0.0205 0.0448 0.5093
Schistosoma mansoni tyrosine kinase 0.043 0.1234 0.1231
Echinococcus granulosus tyrosine protein kinase shark 0.014 0.0222 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0363 0.036
Loa Loa (eye worm) hypothetical protein 0.0084 0.0026 0.0021
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.014 0.0222 0.0203
Schistosoma mansoni protein kinase 0.0174 0.0341 0.0338
Schistosoma mansoni tyrosine kinase 0.02 0.043 0.0427
Echinococcus granulosus tyrosine protein kinase Lyn 0.0386 0.1081 0.1063
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Echinococcus granulosus mitogen activated protein kinase 0.0169 0.0323 0.0304
Trypanosoma brucei protein kinase, putative 0.0169 0.0323 0.0321
Echinococcus multilocularis serine:threonine protein kinase N2 0.0135 0.0202 0.0183
Entamoeba histolytica protein kinase, putative 0.0111 0.012 0.012
Entamoeba histolytica protein kinase, putative 0.0127 0.0176 0.0176
Echinococcus multilocularis expressed protein 0.0111 0.012 0.0101
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0122 0.0157 0.0154
Brugia malayi Fibronectin type III domain containing protein 0.0175 0.0342 0.0327
Echinococcus granulosus neuroglian 0.0201 0.0433 0.0414
Brugia malayi Kinase associated domain 1 family protein 0.0175 0.0344 0.0329
Schistosoma mansoni serine/threonine protein kinase 0.0496 0.1462 0.146
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Echinococcus multilocularis epidermal growth factor receptor 0.0852 0.2705 0.269
Trypanosoma brucei Casein kinase II 0.0205 0.0448 0.0445
Trypanosoma cruzi cdc2-related kinase 1 0.0246 0.0589 0.0587
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0235 0.0553 0.0548
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0144 0.0236 0.0217
Onchocerca volvulus 0.0694 0.2154 0.2131
Trichomonas vaginalis STE family protein kinase 0.0283 0.0721 0.0718
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Loa Loa (eye worm) hypothetical protein 0.0648 0.1994 0.1989
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0562 0.1692 0.1676
Trichomonas vaginalis AGC family protein kinase 0.0607 0.1852 0.185
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0026 0.002
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0094 0.0062 0.0059
Echinococcus granulosus casein kinase I delta 0.0181 0.0363 0.0344
Entamoeba histolytica protein kinase domain containing protein 0.0114 0.013 0.013
Brugia malayi Protein kinase domain containing protein 0.0118 0.0144 0.0129
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0327 0.0875 0.0857
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0113 0.0125 0.0106
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0267 0.0664 0.0659
Brugia malayi Heterochromatin protein 1 0.0084 0.0026 0.0011
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Echinococcus multilocularis mitogen activated protein kinase 0.0169 0.0323 0.0304
Echinococcus granulosus serine:threonine protein kinase N2 0.0135 0.0202 0.0183
Echinococcus multilocularis expressed conserved protein 0.0165 0.0307 0.0288
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0246 0.0589 0.3259
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0538 0.1611 0.1594
Onchocerca volvulus Serine\/threonine kinase homolog 0.0195 0.0414 0.0386
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0333 0.0895 0.0893
Plasmodium vivax unspecified product 0.0205 0.0448 0.5093
Echinococcus granulosus NCK adaptor protein 0.0124 0.0164 0.0145
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0664 0.0662
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0188 0.0387 0.0368
Brugia malayi map kinase activated protein kinase protein 2 0.0844 0.2678 0.2667
Loa Loa (eye worm) AGC/PKA protein kinase 0.0188 0.0387 0.0382
Schistosoma mansoni vesicular amine transporter 0.0164 0.0306 0.0303
Schistosoma mansoni tyrosine kinase 0.1304 0.4283 0.4282
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0253 0.0615 0.061
Schistosoma mansoni serine/threonine protein kinase 0.0325 0.0865 0.0862
Echinococcus granulosus tyrosine protein kinase Btk29A 0.049 0.1442 0.1425
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0323 0.0321
Echinococcus multilocularis ephrin type A receptor 4 A 0.0215 0.0484 0.0465
Brugia malayi serine/threonine-protein kinase PAK 7 0.0492 0.1448 0.1436
Loa Loa (eye worm) hypothetical protein 0.0108 0.011 0.0104
Brugia malayi casein kinase I 0.0181 0.0363 0.0348
Loa Loa (eye worm) hypothetical protein 0.0143 0.0232 0.0227
Loa Loa (eye worm) hypothetical protein 0.0084 0.0026 0.0021
Brugia malayi Protein kinase domain containing protein 0.0608 0.1855 0.1842
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0174 0.0341 0.0322
Brugia malayi Protein kinase domain containing protein 0.0253 0.0615 0.0601
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0113 0.0125 0.0106
Echinococcus granulosus casein kinase I alpha 0.0181 0.0363 0.0344
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0169 0.0323 0.0321
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0169 0.0323 0.0321
Loa Loa (eye worm) hypothetical protein 0.0187 0.0383 0.0378
Onchocerca volvulus 0.0123 0.0161 0.0133
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0268 0.0667 0.0649
Schistosoma mansoni tyrosine kinase 0.0144 0.0236 0.0234
Schistosoma mansoni ephrin receptor 0.0086 0.0034 0.0031
Trichomonas vaginalis CK1 family protein kinase 0.0181 0.0363 0.036
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0188 0.0387 0.0384
Schistosoma mansoni serine/threonine-protein kinase 0.0342 0.0925 0.0923
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0086 0.0034 0.0014
Echinococcus granulosus epidermal growth factor receptor 0.0852 0.2705 0.269
Echinococcus multilocularis rho associated protein kinase 0.0694 0.2154 0.2139
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0236 0.0234
Echinococcus multilocularis tyrosine protein kinase shark 0.014 0.0222 0.0203
Brugia malayi Protein kinase c protein 2 0.023 0.0536 0.0521
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0304 0.0792 0.9033
Schistosoma mansoni serine/threonine kinase 0.0325 0.0865 0.0862
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0103 0.01
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0492 0.1448 0.1444
Brugia malayi Immunoglobulin I-set domain containing protein 0.0106 0.0101 0.0086
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0141 0.0226 0.0206
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0081 0.0015 0.001
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0406 0.115 0.1133
Schistosoma mansoni unc-13 (munc13) 0.0085 0.0029 0.0026
Schistosoma mansoni tyrosine kinase 0.0527 0.1571 0.1569
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0103 0.01
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0188 0.0387 0.0368
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0235 0.0553 0.0539
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0146 0.0243 0.0241
Echinococcus granulosus roundabout 2 0.0086 0.0034 0.0014
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.0925 0.0925
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0406 0.115 0.1145
Entamoeba histolytica tyrosin kinase, putative 0.0083 0.0022 0.0022
Echinococcus multilocularis serine threonine protein kinase 0.0413 0.1175 0.1158
Trichomonas vaginalis CAMK family protein kinase 0.143 0.4723 0.4722
Plasmodium falciparum cGMP-dependent protein kinase 0.0165 0.0307 0.3481
Loa Loa (eye worm) TK protein kinase 0.0543 0.1629 0.1624
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0256 0.0625 0.0623
Leishmania major protein kinase, putative 0.0184 0.0376 0.0373
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0323 0.0321
Schistosoma mansoni protein kinase 0.0174 0.0341 0.0338
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0124 0.0164 0.0159
Brugia malayi Protein kinase domain containing protein 0.0225 0.0518 0.0503
Loa Loa (eye worm) AGC/PKG protein kinase 0.0165 0.0307 0.0301
Schistosoma mansoni cell adhesion molecule 0.0086 0.0034 0.0031
Echinococcus granulosus CDC7 cell division cycle 7 0.0118 0.0144 0.0125
Echinococcus granulosus nervana 2 0.0269 0.067 0.0652
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0129 0.0181 0.0162
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0171 0.033 0.0328
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0128 0.018 0.0178
Loa Loa (eye worm) hypothetical protein 0.0139 0.0218 0.0213
Entamoeba histolytica casein kinase 1, putative 0.0181 0.0363 0.0363
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0164 0.0306 0.0303
Echinococcus granulosus protein tyrosine kinase 0.0602 0.1833 0.1817
Loa Loa (eye worm) hypothetical protein 0.0302 0.0785 0.078
Plasmodium falciparum protein kinase 5 0.0246 0.0589 0.6716
Entamoeba histolytica protein kinase domain containing protein 0.0235 0.0553 0.0553
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0418 0.1191 0.1174
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Schistosoma mansoni hypothetical protein 0.0128 0.018 0.0178
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0085 0.0029 0.001
Echinococcus granulosus serine:threonine protein kinase 0.0235 0.0554 0.0535
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0323 0.0321
Brugia malayi Protein kinase domain containing protein 0.2035 0.6832 0.6827
Echinococcus granulosus casein kinase I alpha 0.0181 0.0363 0.0344
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0188 0.0387 0.0384
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.041 0.1161 0.1157
Echinococcus multilocularis tyrosine protein kinase Abl 0.0372 0.1031 0.1014
Trichomonas vaginalis STE family protein kinase 0.0174 0.0341 0.0338
Echinococcus multilocularis serine:threonine protein kinase 0.0235 0.0554 0.0535
Brugia malayi Protein kinase domain containing protein 0.0325 0.0865 0.0851
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0283 0.0721 0.399
Giardia lamblia Kinase, NEK 0.0283 0.0721 0.0718
Onchocerca volvulus 0.014 0.0222 0.0194
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0106 0.0103 0.0097
Echinococcus granulosus chromobox protein 1 0.0084 0.0026 0.0006
Loa Loa (eye worm) CAMK/PKD protein kinase 0.03 0.0779 0.0774
Loa Loa (eye worm) AGC/NDR protein kinase 0.0325 0.0865 0.086
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0101 0.0098
Brugia malayi intracellular kinase 0.0267 0.0664 0.065
Trichomonas vaginalis CMGC family protein kinase 0.0205 0.0448 0.0445
Echinococcus multilocularis 0.0125 0.017 0.0151
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0323 0.0321
Brugia malayi Protein kinase domain containing protein 0.0406 0.115 0.1137
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0123 0.0162 0.0162
Echinococcus granulosus raf serine:threonine protein kinase 0.0158 0.0285 0.0266
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Plasmodium falciparum casein kinase 1 0.0181 0.0363 0.412
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0181 0.0363 0.0357
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0333 0.0895 0.0893
Onchocerca volvulus 0.0337 0.091 0.0883
Brugia malayi Immunoglobulin I-set domain containing protein 0.0086 0.0034 0.0019
Brugia malayi RhoGAP domain containing protein 0.0082 0.0019 0.0004
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0342 0.0925 0.0923
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0114 0.013 0.0116
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0235 0.023
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0406 0.115 0.1124
Schistosoma mansoni serine/threonine protein kinase 0.0459 0.1335 0.1332
Plasmodium falciparum serine/threonine protein kinase KIN 0.0143 0.0232 0.2629
Leishmania major protein kinase A catalytic subunit isoform 1 0.0188 0.0387 0.0384
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Loa Loa (eye worm) hypothetical protein 0.0096 0.0069 0.0063
Plasmodium vivax casein kinase 1, putative 0.0181 0.0363 0.412
Brugia malayi Temporarily assigned gene name protein 59 0.0128 0.018 0.0165
Giardia lamblia Kinase, STE STE20 0.0174 0.0341 0.0338
Echinococcus granulosus serine:threonine protein kinase 0.0235 0.0554 0.0535
Giardia lamblia Kinase, CMGC GSK 0.0267 0.0664 0.0662
Echinococcus granulosus serine:threonine protein kinase 3 0.0546 0.1636 0.162
Loa Loa (eye worm) SRC-1 0.0327 0.0875 0.087
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.013 0.0128
Entamoeba histolytica protein kinase, putative 0.0141 0.0226 0.0226
Echinococcus multilocularis mitogen activated protein kinase 11 0.0333 0.0895 0.0877
Echinococcus granulosus dual specificity 0.0114 0.013 0.0111
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Brugia malayi Immunoglobulin I-set domain containing protein 0.0543 0.1629 0.1616
Brugia malayi casein kinase 1, delta 0.0181 0.0363 0.0348
Echinococcus granulosus protein kinase C gamma type 0.0413 0.1175 0.1158
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Echinococcus granulosus roundabout 2 0.0251 0.0607 0.0589
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0961 0.3086 0.3073
Echinococcus granulosus tyrosine protein kinase Fyn 0.0327 0.0875 0.0857
Trypanosoma cruzi casein kinase, putative 0.0181 0.0363 0.036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0175 0.0342 0.0327
Plasmodium vivax serine/threonine protein kinase, putative 0.0111 0.012 0.1344
Loa Loa (eye worm) hypothetical protein 0.0164 0.0306 0.0301
Giardia lamblia Kinase, CMGC CDK 0.0246 0.0589 0.0587
Schistosoma mansoni rap gtpase-activating protein 0.0128 0.018 0.0178
Schistosoma mansoni serine/threonine protein kinase 0.0424 0.1211 0.1209
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0188 0.0387 0.0368
Brugia malayi Ras association domain family 1 isoform A 0.0082 0.0019 0.0004
Brugia malayi hypothetical protein 0.0256 0.0624 0.061
Echinococcus granulosus aurora kinase A 0.0304 0.0792 0.0774
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0553 0.0551
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0174 0.0341 0.0322
Trypanosoma brucei rac serine-threonine kinase, putative 0.0607 0.1852 0.185
Loa Loa (eye worm) AGC/PKN protein kinase 0.0459 0.1335 0.133
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0188 0.0387 0.0368
Leishmania major protein kinase A catalytic subunit isoform 2 0.0188 0.0387 0.0384
Echinococcus granulosus casein kinase i 0.0181 0.0363 0.0344
Echinococcus granulosus casein kinase I alpha 0.0181 0.0363 0.0344
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Loa Loa (eye worm) AGC/AKT protein kinase 0.0607 0.1852 0.1847
Loa Loa (eye worm) hypothetical protein 0.0128 0.018 0.0175
Brugia malayi Protein kinase domain containing protein 0.0111 0.012 0.0105
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0164 0.0306 0.0301
Schistosoma mansoni protein kinase 0.0304 0.0792 0.0789
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0546 0.1636 0.1631
Echinococcus granulosus mitogen activated protein kinase 3 0.0169 0.0323 0.0304
Entamoeba histolytica p21-activated kinase 0.0188 0.039 0.039
Loa Loa (eye worm) hypothetical protein 0.0128 0.018 0.0175
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0256 0.0624 0.0606
Schistosoma mansoni protein kinase C mu 0.0082 0.0019 0.0017
Entamoeba histolytica protein kinase, putative 0.0304 0.0792 0.0792
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0165 0.0307 0.0288
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0108 0.011 0.0596
Echinococcus granulosus neuroglian 0.0086 0.0034 0.0014
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0304 0.0792 0.0792
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Loa Loa (eye worm) hypothetical protein 0.0175 0.0342 0.0336
Echinococcus granulosus dual specificity 0.0114 0.013 0.0111
Brugia malayi Protein kinase domain containing protein 0.0648 0.1994 0.1982
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0108 0.011 0.0095
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0304 0.0792 0.0774
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0424 0.1211 0.1193
Schistosoma mansoni protein kinase C mu 0.0382 0.1066 0.1064
Onchocerca volvulus 0.0267 0.0664 0.0637
Brugia malayi Protein kinase domain containing protein 0.059 0.1792 0.178
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.008 0.0012 0.001
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0188 0.0387 0.0373
Entamoeba histolytica protein kinase, putative 0.0304 0.0792 0.0792
Schistosoma mansoni chromobox protein 0.0084 0.0026 0.0023
Trichomonas vaginalis AGC family protein kinase 0.0607 0.1852 0.185
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.1041 0.1038
Echinococcus granulosus hypothetical protein 0.0125 0.017 0.0151
Toxoplasma gondii AGC kinase 0.0188 0.0387 0.2135
Brugia malayi Fes/CIP4 homology domain containing protein 0.0134 0.02 0.0186
Brugia malayi Protein kinase domain containing protein 0.014 0.0222 0.0207
Leishmania major protein kinase, putative 0.0135 0.0204 0.0202
Brugia malayi Protein kinase domain containing protein 0.0235 0.0554 0.054
Brugia malayi hypothetical protein 0.0084 0.0026 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Echinococcus multilocularis chromobox protein 1 0.0084 0.0026 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0128 0.018 0.0178
Trichomonas vaginalis CK1 family protein kinase 0.0181 0.0363 0.036
Entamoeba histolytica protein kinase domain containing protein 0.0304 0.0792 0.0792
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Entamoeba histolytica protein kinase, putative 0.0141 0.0225 0.0225
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0165 0.0307 0.1689
Loa Loa (eye worm) TK protein kinase 0.0204 0.0443 0.0438
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.032 0.0847 0.0842
Trichomonas vaginalis STE family protein kinase 0.0171 0.033 0.0328
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0171 0.033 0.033
Brugia malayi Temporarily assigned gene name protein 59 0.028 0.0711 0.0697
Echinococcus granulosus casein kinase I delta 0.0181 0.0363 0.0344
Trichomonas vaginalis CMGC family protein kinase 0.0246 0.0589 0.0587
Entamoeba histolytica protein kinase, putative 0.0253 0.0615 0.0615
Schistosoma mansoni tyrosine kinase 0.0507 0.1502 0.15
Entamoeba histolytica protein kinase, putative 0.0114 0.013 0.013
Schistosoma mansoni nephrin 0.0211 0.0469 0.0466
Echinococcus multilocularis N chimaerin 0.0146 0.0243 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0589 0.0587
Echinococcus multilocularis tyrosine protein kinase HCK 0.0204 0.0443 0.0424
Plasmodium vivax serine/threonine kinase-1, putative 0.0184 0.0376 0.4271
Echinococcus granulosus cGMP dependent protein kinase 1 0.0165 0.0307 0.0288
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0382 0.1066 0.1061
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0232 0.023
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0143 0.0232 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.1165 0.1163
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0169 0.0323 0.0321
Trypanosoma brucei protein kinase, putative 0.0267 0.0664 0.0662
Echinococcus multilocularis serine:threonine protein kinase 3 0.0546 0.1636 0.162
Echinococcus multilocularis serine:threonine protein kinase N2 0.0459 0.1335 0.1318
Echinococcus multilocularis serine:threonine protein kinase N2 0.0325 0.0865 0.0847
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0181 0.0363 0.0357
Echinococcus granulosus serine:threonine protein kinase N2 0.0459 0.1335 0.1318
Plasmodium falciparum protein kinase, putative 0.0135 0.0204 0.2308
Echinococcus multilocularis casein kinase I delta 0.0181 0.0363 0.0344
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0109 0.0113 0.1257
Schistosoma mansoni serine/threonine-protein kinase 0.0342 0.0925 0.0923
Echinococcus multilocularis c src tyrosine kinase 0.02 0.043 0.0411
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0108 0.011 0.1228
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0353 0.0963 0.0946
Echinococcus granulosus nervana 2 0.0269 0.067 0.0652
Echinococcus multilocularis nervana 2 0.0269 0.067 0.0652
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Brugia malayi Furin-like cysteine rich region family protein 0.1304 0.4283 0.4275
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0232 0.023
Loa Loa (eye worm) CAMK protein kinase 0.0106 0.0101 0.0095
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0593 0.1803 0.1798
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0188 0.0387 0.0368
Brugia malayi Protein kinase domain containing protein 0.0491 0.1445 0.1432
Trypanosoma cruzi Protein kinase B 0.0342 0.0925 0.0923
Schistosoma mansoni atypical protein kinase C 0.06 0.1827 0.1825
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0269 0.067 0.0652
Onchocerca volvulus 0.014 0.0222 0.0194
Echinococcus multilocularis mitogen activated protein kinase 14 0.0333 0.0895 0.0877
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0844 0.2678 0.2674
Brugia malayi hypothetical protein 0.0128 0.018 0.0165
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0106 0.0103 0.01
Echinococcus granulosus ephrin type A receptor 4 A 0.0215 0.0484 0.0465
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0108 0.011 0.0104
Schistosoma mansoni tyrosine kinase 0.0852 0.2705 0.2703
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0406 0.115 0.1133
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0346 0.0939 0.0934
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0232 0.023
Toxoplasma gondii AGC kinase 0.0188 0.0387 0.2135
Entamoeba histolytica SH2-protein kinase domain containing protein 0.014 0.0222 0.0222
Echinococcus multilocularis protein tyrosine kinase 0.0602 0.1833 0.1817
Echinococcus multilocularis casein kinase I alpha 0.0181 0.0363 0.0344
Brugia malayi Variant SH3 domain containing protein 0.0146 0.0243 0.0229
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0164 0.0306 0.0301
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0141 0.0226 0.0207
Schistosoma mansoni hypothetical protein 0.0082 0.0019 0.0017
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0106 0.0103 0.01
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0124 0.0164 0.0159
Brugia malayi protein-tyrosine kinase 0.0268 0.0667 0.0653
Schistosoma mansoni tyrosine kinase 0.02 0.043 0.0427
Brugia malayi Protein kinase domain containing protein 0.0184 0.0376 0.0361
Trichomonas vaginalis AGC family protein kinase 0.0607 0.1852 0.185
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0242 0.0576 0.0562
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0085 0.0029 0.001
Loa Loa (eye worm) hypothetical protein 0.0188 0.0387 0.0382
Brugia malayi cell division control protein 2 homolog 0.0246 0.0589 0.0575
Echinococcus granulosus tyrosine kinase 0.0268 0.0667 0.0649
Loa Loa (eye worm) hypothetical protein 0.0452 0.1311 0.1306
Brugia malayi SRC-1 0.0327 0.0875 0.0861
Schistosoma mansoni vav2 0.0161 0.0293 0.029
Echinococcus granulosus NDR protein kinase 0.0325 0.0865 0.0847
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0164 0.0306 0.0287
Entamoeba histolytica protein kinase , putative 0.0304 0.0792 0.0792
Plasmodium falciparum NIMA related kinase 1 0.0283 0.0721 0.8222
Plasmodium vivax calcium-dependent protein kinase, putative 0.0108 0.011 0.1228
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0353 0.0963 0.0958
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0128 0.018 0.0178
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0129 0.0181 0.0162
Echinococcus granulosus c-Jun N-terminal kinases 0.0562 0.1692 0.1676
Brugia malayi Protein kinase domain containing protein 0.0607 0.1852 0.184
Entamoeba histolytica casein kinase, putative 0.0181 0.0363 0.0363
Loa Loa (eye worm) TK/ALK protein kinase 0.059 0.1792 0.1787
Echinococcus multilocularis death associated protein kinase 1 0.1831 0.6122 0.6114
Trichomonas vaginalis CK1 family protein kinase 0.0181 0.0363 0.036
Loa Loa (eye worm) hypothetical protein 0.0253 0.0616 0.0611
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0108 0.011 0.0091
Brugia malayi Tyrosine-protein kinase abl-1 0.0278 0.0704 0.069
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0328 0.0876 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0108 0.011 0.0091
Giardia lamblia Kinase, CMGC GSK 0.0267 0.0664 0.0662
Echinococcus granulosus activin receptor type 0.0135 0.0204 0.0185
Echinococcus granulosus Protein kinase C brain isozyme 0.0496 0.1462 0.1446
Brugia malayi STE20-like kinase MST 0.0546 0.1636 0.1623
Trichomonas vaginalis CAMK family protein kinase 0.0235 0.0554 0.0551
Echinococcus granulosus N chimaerin 0.0146 0.0243 0.0224
Brugia malayi Protein kinase domain containing protein 0.032 0.0847 0.0834
Echinococcus multilocularis roundabout 2 0.0251 0.0607 0.0589
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0267 0.0664 0.0659
Onchocerca volvulus 0.014 0.0222 0.0194
Schistosoma mansoni protein kinase 0.0473 0.1383 0.1381
Loa Loa (eye worm) hypothetical protein 0.0086 0.0034 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.0376 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.0694 0.2154 0.2152
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0353 0.0963 0.095
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Schistosoma mansoni protein kinase 0.0108 0.011 0.0107
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0387 0.0385
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.1041 0.1038
Trypanosoma brucei SNF1-related protein kinases, putative 0.0143 0.0232 0.023
Brugia malayi Protein kinase domain containing protein 0.04 0.1128 0.1114
Brugia malayi Variant SH3 domain containing protein 0.0124 0.0164 0.0149
Echinococcus multilocularis RNA directed DNA polymerase 0.0086 0.0033 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0236 0.0234
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0253 0.0615 0.0613
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0327 0.0875 0.0857
Trichomonas vaginalis STE family protein kinase 0.0174 0.0341 0.0338
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0188 0.0387 0.0384
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0188 0.0387 0.0368
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0406 0.115 0.1137
Loa Loa (eye worm) hypothetical protein 0.0249 0.06 0.0595
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0108 0.011 0.0104
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Loa Loa (eye worm) TK/ROR protein kinase 0.0113 0.0125 0.012
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0106 0.0103 0.0088
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0108 0.011 0.0091
Schistosoma mansoni tyrosine kinase 0.0852 0.2705 0.2703
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0507 0.1503 0.1486
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0306 0.0304
Brugia malayi putative serine/threonine kinase SADA gamma 0.0143 0.0232 0.0218
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.013 0.0128
Brugia malayi protein kinase C3,putative 0.0321 0.0854 0.084
Echinococcus granulosus tyrosine protein kinase Fyn 0.0327 0.0875 0.0857
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0287 0.0733 0.0731
Entamoeba histolytica hypothetical protein 0.0253 0.0615 0.0615
Schistosoma mansoni protein kinase 0.0108 0.011 0.0107
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0143 0.0232 0.023
Loa Loa (eye worm) TK/ABL protein kinase 0.0591 0.1795 0.1791
Brugia malayi Protein kinase domain containing protein 0.0246 0.0589 0.0575
Echinococcus granulosus Immunoglobulin 0.0164 0.0306 0.0287
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0267 0.0664 0.0662
Brugia malayi Protein kinase domain containing protein 0.014 0.0222 0.0207
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0204 0.0445 0.0426
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0145 0.024 0.0234
Loa Loa (eye worm) CDC7 protein kinase 0.0118 0.0144 0.0139
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0225 0.0518 0.0513
Schistosoma mansoni protein kinase 0.0418 0.1191 0.1189
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Echinococcus granulosus myotubularin protein 13 0.0096 0.0069 0.0049
Echinococcus multilocularis hypothetical protein 0.0175 0.0344 0.0325
Schistosoma mansoni titin 0.0106 0.0101 0.0098
Trypanosoma brucei cdc2-related kinase 1 0.0246 0.0589 0.0587
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0418 0.1191 0.1174
Echinococcus multilocularis casein kinase I delta 0.0181 0.0363 0.0344
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.013 0.0128
Echinococcus granulosus epidermal growth factor receptor 0.1304 0.4283 0.4272
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0507 0.1503 0.1498
Trypanosoma cruzi casein kinase, putative 0.0181 0.0363 0.036
Giardia lamblia Kinase, CAMK CAMKL 0.0143 0.0232 0.023
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0333 0.0895 0.0893
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0256 0.0624 0.0619
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0171 0.033 0.033
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0171 0.033 0.0328
Plasmodium falciparum calcium-dependent protein kinase 3 0.0108 0.011 0.1228
Entamoeba histolytica protein kinase, putative 0.0267 0.0664 0.0664
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0615 0.0613
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0246 0.0589 0.0584
Loa Loa (eye worm) AUR protein kinase 0.0304 0.0792 0.0787
Brugia malayi Immunoglobulin I-set domain containing protein 0.1336 0.4394 0.4386
Onchocerca volvulus 0.014 0.0222 0.0194
Entamoeba histolytica serine/threonine protein kinase, putative 0.0143 0.0232 0.0232
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0188 0.0387 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0307 0.0304
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0143 0.0232 0.0213
Trichomonas vaginalis CMGC family protein kinase 0.0205 0.0448 0.0445
Schistosoma mansoni protein kinase 0.0205 0.0448 0.0445
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0205 0.0448 0.5093
Entamoeba histolytica protein kinase, putative 0.0141 0.0225 0.0225
Brugia malayi serine/threonine protein kinase 6 0.0304 0.0792 0.0778
Brugia malayi serine/threonine-protein kinase 6 0.0304 0.0792 0.0778
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.0925 0.0925
Echinococcus multilocularis casein kinase I gamma 0.0121 0.0156 0.0137
Echinococcus multilocularis roundabout 2 0.0086 0.0034 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0144 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0387 0.0384
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.0315
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0235 0.0553 0.0535
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0852 0.2705 0.269
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0205 0.0448 0.0442
Brugia malayi RhoGAP domain containing protein 0.0146 0.0243 0.0229
Entamoeba histolytica protein kinase, putative 0.0164 0.0306 0.0306
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.0376 0.0373
Schistosoma mansoni tyrosine kinase 0.0776 0.2439 0.2437
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0108 0.011 0.0091
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0325 0.0865 0.0847
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.013 0.0128
Loa Loa (eye worm) TK/FER protein kinase 0.014 0.0222 0.0217
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0144 0.0142
Schistosoma mansoni tyrosine kinase 0.014 0.0222 0.022
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0591 0.1795 0.1779
Onchocerca volvulus 0.1056 0.3416 0.3397
Loa Loa (eye worm) hypothetical protein 0.0194 0.0409 0.0404
Schistosoma mansoni protein kinase 0.0108 0.011 0.0107
Echinococcus granulosus cGMP dependent protein kinase 1 0.0165 0.0307 0.0288
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0306 0.0304
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0187 0.0386 0.0367
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.2188 0.7366 0.736
Giardia lamblia Kinase, NEK 0.0283 0.0721 0.0718
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0328 0.0876 0.0874
Echinococcus granulosus calcium activated potassium channel 0.0234 0.055 0.0531
Giardia lamblia Kinase, NEK 0.0283 0.0721 0.0718
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Plasmodium falciparum calcium-dependent protein kinase 1 0.0108 0.011 0.1228
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0304 0.0792 0.0792
Echinococcus multilocularis cyclin dependent kinase 1 0.0246 0.0589 0.0571
Entamoeba histolytica protein kinase, putative 0.0108 0.011 0.011
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0325 0.0865 0.0847
Brugia malayi Egg laying defective protein 4 0.0165 0.0307 0.0292
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0141 0.0226 0.0207
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0479 0.1405 0.14
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0108 0.011 0.1228
Toxoplasma gondii casein kinase I 0.0181 0.0363 0.1999
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0181 0.0366 0.036
Schistosoma mansoni tyrosine kinase 0.0951 0.305 0.3049
Trichomonas vaginalis AGC family protein kinase 0.0346 0.0939 0.0937
Onchocerca volvulus 0.0128 0.018 0.0152
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0082 0.0019 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0135 0.0132
Brugia malayi serine/threonine kinase 12 0.0304 0.0792 0.0778
Trichomonas vaginalis AGC family protein kinase 0.0283 0.0721 0.0718
Giardia lamblia Kinase, AGC PKA 0.0188 0.0387 0.0384
Brugia malayi Sex muscle abnormal protein 5 0.0124 0.0164 0.0149
Echinococcus multilocularis calcium activated potassium channel 0.0234 0.055 0.0531
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0128 0.018 0.0161
Brugia malayi Hr1 repeat family protein 0.0459 0.1335 0.1322
Echinococcus granulosus insulin receptor 0.0951 0.305 0.3037
Giardia lamblia Kinase, AGC AKT 0.0242 0.0576 0.0574
Loa Loa (eye worm) hypothetical protein 0.0115 0.0135 0.0129
Echinococcus multilocularis dual specificity 0.0114 0.013 0.0111
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0205 0.0448 0.0445
Brugia malayi Protein kinase domain containing protein 0.0195 0.0414 0.0399
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0424 0.1211 0.1193
Loa Loa (eye worm) RasGEF domain-containing protein 0.0082 0.0019 0.0014
Schistosoma mansoni protein kinase 0.0135 0.0204 0.0202
Trypanosoma cruzi p21-activated kinase 3, putative 0.0106 0.0103 0.01
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0111 0.012 0.0117
Loa Loa (eye worm) AUR protein kinase 0.0304 0.0792 0.0787
Trichomonas vaginalis AGC family protein kinase 0.0607 0.1852 0.185
Giardia lamblia Kinase, CMGC DYRK 0.0114 0.013 0.0128
Schistosoma mansoni kinase 0.1815 0.6064 0.6063
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0106 0.0101 0.0095
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0184 0.0376 0.2073
Echinococcus granulosus contactin 0.0086 0.0034 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0325 0.0865 0.0863
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0406 0.115 0.1145
Echinococcus granulosus mitogen activated protein kinase 11 0.0333 0.0895 0.0877
Echinococcus granulosus cyclin dependent kinase 0.0246 0.0589 0.0571
Echinococcus multilocularis protein kinase c epsilon type 0.041 0.1161 0.1144
Brugia malayi Protein kinase domain containing protein 0.0121 0.0156 0.0141
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.02 0.043 0.0427
Brugia malayi probable protein kinase 0.0312 0.0822 0.0808
Loa Loa (eye worm) raf kinase 0.0082 0.0019 0.0014
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0143 0.0232 0.023
Giardia lamblia Kinase, CAMK CAMKL 0.0143 0.0232 0.023
Echinococcus granulosus expressed protein 0.0111 0.012 0.0101
Entamoeba histolytica protein kinase, putative 0.0593 0.1803 0.1803
Loa Loa (eye worm) hypothetical protein 0.0241 0.0572 0.0566
Schistosoma mansoni vam6/vps39 related 0.0128 0.018 0.0178
Entamoeba histolytica protein kinase domain containing protein 0.0253 0.0615 0.0615
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0327 0.0875 0.0857
Echinococcus multilocularis dual specificity 0.0114 0.013 0.0111
Trichomonas vaginalis STE family protein kinase 0.0174 0.0341 0.0338
Echinococcus granulosus casein kinase ii subunit alpha 0.0205 0.0448 0.0429
Entamoeba histolytica protein kinase domain containing protein 0.0267 0.0664 0.0664
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0327 0.0875 0.0857
Loa Loa (eye worm) hypothetical protein 0.0302 0.0785 0.078
Giardia lamblia Aurora kinase 0.0304 0.0792 0.0789
Loa Loa (eye worm) hypothetical protein 0.0323 0.086 0.0855
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Echinococcus multilocularis casein kinase I alpha 0.0181 0.0363 0.0344
Brugia malayi ephrin receptor 1 precursor 0.0142 0.0227 0.0212
Echinococcus granulosus chromobox protein 1 0.0084 0.0026 0.0006
Schistosoma mansoni adapter molecule crk 0.0124 0.0164 0.0161
Echinococcus granulosus tyrosine protein kinase Src42A 0.0327 0.0875 0.0857
Echinococcus granulosus serine/threonine protein kinase 0.0342 0.0925 0.0908
Echinococcus multilocularis twitchin 0.0095 0.0065 0.0046
Loa Loa (eye worm) TK protein kinase 0.0268 0.0667 0.0662
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Entamoeba histolytica protein kinase, putative 0.0253 0.0615 0.0615
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0253 0.0615 0.0613
Plasmodium falciparum protein serine/threonine kinase-1 0.0184 0.0376 0.4271
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0181 0.0363 0.036
Brugia malayi Tyrosine-protein kinase abl-1 0.0372 0.1031 0.1018
Loa Loa (eye worm) hypothetical protein 0.0164 0.0306 0.0301
Loa Loa (eye worm) hypothetical protein 0.0337 0.091 0.0905
Entamoeba histolytica casein kinase, putative 0.0205 0.0448 0.0448
Echinococcus granulosus growth factor receptor bound protein 2 0.0124 0.0164 0.0145
Loa Loa (eye worm) TK/EPH protein kinase 0.0254 0.0617 0.0612
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0174 0.0341 0.0322
Toxoplasma gondii diacylglycerol kinase, putative 0.0082 0.0019 0.0093
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0188 0.0387 0.2135
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0082 0.0019 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0184 0.0376 0.0373
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0114 0.013 0.0128
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0246 0.0589 0.0587
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Trypanosoma brucei casein kinase I, isoform 2 0.0181 0.0363 0.036
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0195 0.0414 0.0395
Echinococcus multilocularis rac serine:threonine kinase 0.0342 0.0925 0.0908
Onchocerca volvulus 0.0302 0.0785 0.0758
Brugia malayi Protein kinase domain containing protein 0.014 0.0222 0.0207
Schistosoma mansoni chromobox protein 0.0084 0.0026 0.0023
Echinococcus multilocularis dual specificity 0.0114 0.013 0.0111
Loa Loa (eye worm) hypothetical protein 0.0082 0.0019 0.0014
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0235 0.023
Onchocerca volvulus 0.0139 0.0218 0.0189
Brugia malayi diacylglycerol kinase 0.0082 0.0019 0.0004
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0144 0.0236 0.0217
Onchocerca volvulus 0.0106 0.0101 0.0072
Echinococcus multilocularis CDC7 cell division cycle 7 0.0118 0.0144 0.0125
Schistosoma mansoni serine/threonine kinase 0.032 0.0847 0.0845
Echinococcus multilocularis protein kinase c iota type 0.0587 0.1781 0.1765
Brugia malayi MH2 domain containing protein 0.0144 0.0235 0.0221
Echinococcus granulosus tyrosine kinase 0.014 0.0222 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.0792 0.0789
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0086 0.0034 0.0014
Echinococcus granulosus cyclin dependent kinase 1 0.0246 0.0589 0.0571
Echinococcus multilocularis activin receptor type 0.0135 0.0204 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.1503 0.15
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0164 0.0306 0.0287
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Echinococcus granulosus RNA directed DNA polymerase 0.0086 0.0033 0.0014
Brugia malayi phosphoinositide-dependent protein kinase I 0.0164 0.0306 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.0325 0.0865 0.0862
Schistosoma mansoni protein kinase C 0.0085 0.0029 0.0026
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0169 0.0323 0.0318
Loa Loa (eye worm) hypothetical protein 0.014 0.0222 0.0217
Entamoeba histolytica PH domain containing protein kinase, putative 0.0202 0.0436 0.0436
Plasmodium vivax tyrosine kinase-like protein, putative 0.0109 0.0113 0.1257
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0108 0.011 0.0091
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0333 0.0895 0.089
Brugia malayi Protein kinase domain containing protein 0.0424 0.1211 0.1198
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0195 0.0414 0.0408
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0165 0.0307 0.0288
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0491 0.1445 0.144
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0307 0.0304
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0108 0.011 0.0107
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0111 0.012 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.029 0.0743 0.0741
Schistosoma mansoni growth factor receptor-bound protein 0.0124 0.0164 0.0161
Toxoplasma gondii histone kinase SNF1, putative 0.0143 0.0232 0.1276
Plasmodium vivax protein kinase Crk2 0.0246 0.0589 0.6716
Onchocerca volvulus 0.0122 0.0157 0.0128
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0507 0.1502 0.1485
Brugia malayi Protein kinase domain containing protein 0.0648 0.1994 0.1982
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0328 0.0876 0.0858
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0184 0.0374 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0226 0.0223
Echinococcus multilocularis cyclin dependent kinase 5 0.0246 0.0589 0.0571
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0169 0.0323 0.0321
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0169 0.0323 0.0321
Echinococcus granulosus titin 0.0106 0.0101 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0607 0.1852 0.185
Giardia lamblia Kinase, CMGC SRPK 0.0111 0.012 0.0117
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0148 0.0249 0.0243
Echinococcus multilocularis protein kinase shaggy 0.0267 0.0664 0.0646
Entamoeba histolytica protein kinase, putative 0.0174 0.0341 0.0341
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0246 0.0589 0.0584
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Schistosoma mansoni nephrin 0.0086 0.0034 0.0031
Echinococcus granulosus serine threonine protein kinase nrc 0.0328 0.0876 0.0858
Loa Loa (eye worm) hypothetical protein 0.0302 0.0785 0.078
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0507 0.1503 0.1486
Entamoeba histolytica protein kinase, putative 0.0123 0.0162 0.0162
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0108 0.011 0.0091
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0267 0.0664 0.3675
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.008 0.0012 0.001
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.071 0.2211 0.2206
Loa Loa (eye worm) hypothetical protein 0.0241 0.0573 0.0568
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0184 0.0376 0.0373
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0124 0.0164 0.0161
Entamoeba histolytica cell division protein kinase 2, putative 0.0246 0.0589 0.0589
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0065 0.0062
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0174 0.0341 0.0322
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0253 0.0615 0.0613
Onchocerca volvulus 0.014 0.0222 0.0194
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0188 0.0387 0.0384
Brugia malayi Casein kinase II, alpha chain 0.0205 0.0448 0.0433
Schistosoma mansoni serine/threonine protein kinase 0.0406 0.115 0.1148
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0174 0.0341 0.0322
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0304 0.0792 0.0792
Trichomonas vaginalis AGC family protein kinase 0.0304 0.0792 0.0789
Echinococcus granulosus cyclin dependent kinase 5 0.0246 0.0589 0.0571
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0135 0.0204 0.112
Trichomonas vaginalis AGC family protein kinase 0.0607 0.1852 0.185
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0086 0.0034 0.0014
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0375 0.1041 0.1023
Plasmodium falciparum glycogen synthase kinase 3 0.0267 0.0664 0.7573
Loa Loa (eye worm) hypothetical protein 0.0082 0.0019 0.0014
Schistosoma mansoni diacylglycerol kinase theta 0.0082 0.0019 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0205 0.0448 0.0445
Loa Loa (eye worm) hypothetical protein 0.0241 0.0572 0.0566
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0267 0.0664 0.0662
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0146 0.0243 0.0224
Loa Loa (eye worm) hypothetical protein 0.0175 0.0344 0.0338
Loa Loa (eye worm) hypothetical protein 0.0125 0.017 0.0164
Echinococcus granulosus protein kinase 0.0184 0.0374 0.0355
Trichomonas vaginalis AGC family protein kinase 0.0304 0.0792 0.0789
Trichomonas vaginalis CMGC family protein kinase 0.0205 0.0448 0.0445
Entamoeba histolytica protein kinase 2, putative 0.0328 0.0876 0.0876
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0496 0.1462 0.1446
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Loa Loa (eye worm) hypothetical protein 0.0235 0.0554 0.0549
Brugia malayi Protein kinase domain containing protein 0.0089 0.0043 0.0028
Onchocerca volvulus 0.014 0.0222 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0589 0.0587
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0204 0.0204
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0144 0.0142
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0507 0.1502 0.1485
Trichomonas vaginalis AGC family protein kinase 0.0304 0.0792 0.0789
Loa Loa (eye worm) hypothetical protein 0.0082 0.0019 0.0014
Echinococcus granulosus casein kinase I gamma 0.0121 0.0156 0.0137
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0111 0.012 0.0652
Brugia malayi Stress-activated protein kinase jnk-1 0.0562 0.1692 0.168
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0143 0.0232 0.2629
Schistosoma mansoni cell adhesion molecule 0.0214 0.048 0.0478
Echinococcus granulosus unc 13 munc13 0.0085 0.0029 0.001
Schistosoma mansoni tyrosine kinase 0.0602 0.1833 0.1831
Echinococcus multilocularis aurora kinase A 0.0304 0.0792 0.0774
Schistosoma mansoni ste20-related kinase 0.0433 0.1244 0.1242
Echinococcus granulosus twitchin 0.026 0.0639 0.062
Schistosoma mansoni serine/threonine protein kinase 0.0353 0.0963 0.0961
Loa Loa (eye worm) protein kinase domain-containing protein 0.0121 0.0156 0.0151
Echinococcus granulosus tyrosine protein kinase Blk 0.0268 0.0667 0.0649
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1336 0.4394 0.4391
Schistosoma mansoni protein kinase 0.0181 0.0363 0.036
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0128 0.018 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.055 0.0547
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0169 0.0323 0.0321
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0961 0.3086 0.3073
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0256 0.0624 0.0606
Giardia lamblia Kinase, CMGC CDK 0.0246 0.0589 0.0587
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0108 0.011 0.0091
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0375 0.1041 0.1023
Echinococcus multilocularis epidermal growth factor receptor 0.1304 0.4283 0.4272
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0188 0.0387 0.0368
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0269 0.067 0.0652
Echinococcus multilocularis nervana 2 0.0269 0.067 0.0652
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0143 0.0232 0.023
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0026 0.0023
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0382 0.1066 0.1053
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0188 0.0387 0.44
Brugia malayi Variant SH3 domain containing protein 0.0124 0.0164 0.0149
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Echinococcus granulosus defective proboscis extension response 0.0164 0.0306 0.0287
Echinococcus multilocularis serine:threonine protein kinase 0.0235 0.0554 0.0535
Loa Loa (eye worm) hypothetical protein 0.0086 0.0033 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.0624 0.0622
Entamoeba histolytica protein kinase, putative 0.0111 0.012 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0444 0.0441
Brugia malayi Immunoglobulin I-set domain containing protein 0.0086 0.0034 0.0019
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0353 0.0963 0.0946
Toxoplasma gondii CMGC kinase, CK2 family 0.0205 0.0448 0.2472
Leishmania major protein kinase, putative 0.0171 0.033 0.0328
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0424 0.1211 0.1206
Echinococcus multilocularis casein kinase I alpha 0.0181 0.0363 0.0344
Entamoeba histolytica protein kinase, putative 0.0607 0.1852 0.1852
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0328 0.0876 0.0858
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0146 0.0243 0.0238
Echinococcus granulosus serine:threonine kinase SAD 1 0.0143 0.0232 0.0213
Loa Loa (eye worm) TK/FAK protein kinase 0.0608 0.1855 0.185
Brugia malayi protein kinase C II. 0.041 0.1161 0.1148
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0169 0.0323 0.1782
Echinococcus multilocularis insulin receptor 0.0951 0.305 0.3037
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0192 0.0401 0.0382
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0327 0.0875 0.0857
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.008 0.0012 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0285 0.0283
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0411 0.1165 0.1148
Echinococcus granulosus mitogen activated protein kinase 14 0.0333 0.0895 0.0877
Echinococcus multilocularis dual specificity protein kinase clk2 0.0184 0.0376 0.0357
Plasmodium falciparum calcium-dependent protein kinase 4 0.0108 0.011 0.1228
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0562 0.1692 0.1688
Brugia malayi Protein kinase domain containing protein 0.0951 0.305 0.304
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0086 0.0034 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.041 0.1161 0.1159
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0335 0.09 0.0895
Trypanosoma cruzi casein kinase, putative 0.0181 0.0363 0.036
Echinococcus multilocularis unc 13 (munc13) 0.0085 0.0029 0.001
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0325 0.0865 0.0847
Echinococcus multilocularis neuroglian 0.0086 0.0034 0.0014
Trypanosoma brucei protein kinase, putative 0.0135 0.0204 0.0202
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0648 0.1994 0.1989
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.055 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0562 0.1692 0.169
Brugia malayi Protein kinase domain containing protein 0.014 0.0222 0.0207
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0333 0.0895 0.0893
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0411 0.1165 0.1148
Brugia malayi Protein kinase domain containing protein 0.0388 0.1087 0.1074
Leishmania major casein kinase, putative 0.0181 0.0363 0.036
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0114 0.013 0.071
Brugia malayi SH2 domain containing protein 0.014 0.0222 0.0207
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0844 0.2678 0.2664
Echinococcus granulosus tyrosine protein kinase HCK 0.0204 0.0443 0.0424
Trypanosoma brucei cdc2-related kinase 3 0.0246 0.0589 0.0587
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0114 0.013 0.0125
Onchocerca volvulus 0.0181 0.0363 0.0334
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2035 0.6832 0.683
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0128 0.018 0.0178
Brugia malayi Serine/threonine-protein kinase SULU 0.0256 0.0624 0.061
Brugia malayi Cam kinase protein 1 0.0108 0.011 0.0095
Echinococcus multilocularis serine:threonine protein kinase 38 0.0325 0.0865 0.0847
Brugia malayi diacylglycerol kinase 0.0082 0.0019 0.0004
Entamoeba histolytica protein kinase, putative 0.0607 0.1852 0.1852
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.011 0.0107
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0184 0.0376 0.0373
Entamoeba histolytica diacylglycerol kinase, putative 0.0082 0.0019 0.0019
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0267 0.0664 0.0646
Schistosoma mansoni hypothetical protein 0.0175 0.0344 0.0341
Entamoeba histolytica hypothetical protein 0.0082 0.0019 0.0019
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0181 0.0363 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0156 0.0153
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0128 0.018 0.0178
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0473 0.1383 0.1367
Trypanosoma cruzi casein kinase, putative 0.0181 0.0363 0.036
Schistosoma mansoni protein kinase 0.0225 0.0518 0.0515
Entamoeba histolytica protein kinase domain containing protein 0.0083 0.0022 0.0022
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0184 0.0376 0.0373
Loa Loa (eye worm) hypothetical protein 0.0082 0.0019 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0232 0.023
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0664 0.0662
Echinococcus granulosus tyrosine protein kinase Src64B 0.0327 0.0875 0.0857
Schistosoma mansoni unc-13 (munc13) 0.0085 0.0029 0.0026
Echinococcus granulosus protein kinase c iota type 0.0587 0.1781 0.1765
Loa Loa (eye worm) TK/INSR protein kinase 0.0951 0.305 0.3047
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0306 0.0304
Schistosoma mansoni rac gtpase activating protein 0.0082 0.0019 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.055 0.0547
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0062 0.0059
Brugia malayi protein unc-22 0.0106 0.0101 0.0086
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0169 0.0323 0.0321
Brugia malayi Immunoglobulin I-set domain containing protein 0.0086 0.0034 0.0019
Leishmania major casein kinase II, putative 0.0205 0.0448 0.0445
Giardia lamblia Kinase, CK1 Casein kinase 0.0181 0.0363 0.036
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0146 0.0243 0.0241
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0187 0.0386 0.0367
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0538 0.1611 0.1594
Echinococcus multilocularis myotubularin protein 13 0.0096 0.0069 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0304 0.0792 0.0789
Echinococcus granulosus tyrosine protein kinase Fps85D 0.014 0.0222 0.0203
Echinococcus granulosus dual specificity protein kinase clk2 0.0184 0.0376 0.0357
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0086 0.0033 0.0014
Schistosoma mansoni tyrosine kinase 0.0327 0.0875 0.0872
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0844 0.2678 0.2664
Echinococcus multilocularis growth factor receptor bound protein 2 0.0124 0.0164 0.0145
Loa Loa (eye worm) hypothetical protein 0.0384 0.1072 0.1067
Loa Loa (eye worm) hypothetical protein 0.0175 0.0342 0.0336
Trichomonas vaginalis CMGC family protein kinase 0.0205 0.0448 0.0445
Trypanosoma cruzi cdc2-related kinase 1 0.0246 0.0589 0.0587
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0188 0.0387 0.0384
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0411 0.1165 0.1148
Loa Loa (eye worm) hypothetical protein 0.0204 0.0445 0.0439
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.013 0.0128
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0184 0.0376 0.0373
Toxoplasma gondii aurora kinase 0.0304 0.0792 0.4383
Echinococcus multilocularis mitogen activated protein kinase 14 0.0333 0.0895 0.0877
Trichomonas vaginalis CAMK family protein kinase 0.0143 0.0232 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0844 0.2678 0.2676
Trichomonas vaginalis CMGC family protein kinase 0.0246 0.0589 0.0587
Loa Loa (eye worm) thyroid receptor interactor 0.0134 0.02 0.0195
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0327 0.0875 0.0857
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0146 0.0243 0.0224
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0246 0.0589 0.0571
Trichomonas vaginalis AGC family protein kinase 0.008 0.0012 0.001
Brugia malayi RhoGEF domain containing protein 0.0082 0.0019 0.0004
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0328 0.0876 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0019 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.032 0.0847 0.0845
Trypanosoma cruzi aurora B kinase, putative 0.0304 0.0792 0.0789
Brugia malayi P38 map kinase family protein 2 0.0333 0.0895 0.0881

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0029 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 5.0119 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of GLP-1 Receptor Agonists. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 13.4591 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3489 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 56.2341 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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