Detailed information for compound 1446684

Basic information

Technical information
  • TDR Targets ID: 1446684
  • Name: butyl 3-chloro-4-hydroxy-5-methoxybenzoate
  • MW: 258.698 | Formula: C12H15ClO4
  • H donors: 1 H acceptors: 2 LogP: 3.27 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCOC(=O)c1cc(Cl)c(c(c1)OC)O
  • InChi: 1S/C12H15ClO4/c1-3-4-5-17-12(15)8-6-9(13)11(14)10(7-8)16-2/h6-7,14H,3-5H2,1-2H3
  • InChiKey: DIVMDOLWRYXUNN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • butyl 3-chloro-4-hydroxy-5-methoxy-benzoate
  • 3-chloro-4-hydroxy-5-methoxybenzoic acid butyl ester
  • 3-chloro-4-hydroxy-5-methoxy-benzoic acid butyl ester
  • 5438-56-2
  • NSC16703
  • MLS000737809
  • SMR000528169

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens adrenoceptor beta 2, surface Starlite/ChEMBL No references
Homo sapiens glutaminase Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Mycobacterium ulcerans glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Loa Loa (eye worm) glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Brugia malayi glutaminase DH11.1 Get druggable targets OG5_129245 All targets in OG5_129245
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) glutaminase 2 Get druggable targets OG5_129245 All targets in OG5_129245
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis glutaminase, putative Get druggable targets OG5_129245 All targets in OG5_129245
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis neuroglian 0.0128 0.0246 0.0328
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0179 0.0486 0.0655
Schistosoma mansoni protein kinase 0.0431 0.1655 0.2621
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0342 0.0338
Echinococcus granulosus mitogen activated protein kinase 11 0.0299 0.1041 0.1167
Trichomonas vaginalis AGC family protein kinase 0.0436 0.1679 0.7628
Echinococcus granulosus cyclin dependent kinase 5 0.0219 0.0672 0.0751
Trypanosoma brucei protein kinase, putative 0.0125 0.0233 0.1037
Echinococcus multilocularis mitogen activated protein kinase 11 0.0299 0.1041 0.1411
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0351 0.1586
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0435 0.0683
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0293 0.1012 0.1134
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0465 0.1812 0.2461
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0521 0.2075 0.2305
Echinococcus multilocularis serine:threonine protein kinase 3 0.0491 0.1935 0.2629
Schistosoma mansoni tyrosine kinase 0.0489 0.1925 0.3049
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0179 0.0483 0.0538
Echinococcus granulosus tyrosine protein kinase Fyn 0.0343 0.1247 0.1399
Echinococcus granulosus ephrin type A receptor 4 A 0.02 0.0583 0.0651
Trypanosoma cruzi cdc2-related kinase 1 0.0219 0.0672 0.325
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0166 0.0422 0.0418
Schistosoma mansoni serine/threonine protein kinase 0.0436 0.1679 0.2658
Echinococcus granulosus dual specificity 0.0154 0.0368 0.0409
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0155 0.0372 0.05
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0076 0.0007 0.0002
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0343 0.1247 0.1692
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0168 0.0435 0.2569
Brugia malayi Immunoglobulin I-set domain containing protein 0.0097 0.0104 0.0099
Entamoeba histolytica PH domain containing protein kinase, putative 0.0181 0.0495 0.2248
Toxoplasma gondii AGC kinase 0.0168 0.0435 0.2014
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0299 0.1041 0.5047
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0239 0.0762 0.369
Brugia malayi serine/threonine-protein kinase plk-2 0.0518 0.2058 0.2054
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0271 0.091 0.1233
Echinococcus granulosus nervana 2 0.0243 0.0783 0.0876
Brugia malayi Protein kinase domain 0.0155 0.0372 0.0367
Echinococcus granulosus casein kinase I gamma 0.0227 0.0706 0.0789
Echinococcus granulosus roundabout 2 0.0128 0.0246 0.0271
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0179 0.0483 0.0478
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.0658 0.2989
Entamoeba histolytica protein kinase, putative 0.0548 0.22 1
Giardia lamblia Kinase, CMGC MAPK 0.015 0.0351 0.1218
Echinococcus granulosus casein kinase I delta 0.0162 0.0405 0.045
Plasmodium falciparum cGMP-dependent protein kinase 0.015 0.0349 0.1547
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0145 0.0646
Echinococcus multilocularis casein kinase i 0.0162 0.0405 0.0545
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0125 0.0231 0.1052
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0294 0.1018 0.5802
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0139 0.0299 0.0401
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0672 0.106
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0665 0.2741 0.3081
Loa Loa (eye worm) TK/FER protein kinase 0.0445 0.1721 0.1717
Loa Loa (eye worm) AUR protein kinase 0.0436 0.1679 0.1675
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0085 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0368 0.0577
Schistosoma mansoni ste20-related kinase 0.0389 0.1462 0.2314
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0641 0.2633 0.2629
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0331 0.1492
Entamoeba histolytica protein kinase, putative 0.01 0.0115 0.0521
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Echinococcus granulosus activin receptor type 0.0125 0.0233 0.0256
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0229 0.0716 0.3463
Echinococcus multilocularis growth factor receptor bound protein 2 0.0125 0.0232 0.0309
Echinococcus granulosus dual specificity 0.0154 0.0368 0.0409
Echinococcus multilocularis microtubule associated protein 2 0.143 0.6302 0.8576
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0007 0.0002
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0089 0.0068 0.0063
Echinococcus granulosus defective proboscis extension response 0.0215 0.0651 0.0728
Onchocerca volvulus Netrin receptor homolog 0.0082 0.0033 0.0031
Onchocerca volvulus Serine\/threonine kinase homolog 0.0518 0.2058 0.2286
Loa Loa (eye worm) AUR protein kinase 0.0436 0.1679 0.1675
Trichomonas vaginalis AGC family protein kinase 0.0548 0.22 1
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0219 0.0339
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0299 0.1041 0.1037
Trichomonas vaginalis AGC family protein kinase 0.0548 0.22 1
Echinococcus granulosus tyrosine kinase 0.0149 0.0342 0.038
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0139 0.0299 0.1341
Schistosoma mansoni protein kinase 0.0288 0.099 0.1565
Giardia lamblia Kinase, CMGC CLK 0.0168 0.0435 0.1649
Loa Loa (eye worm) hypothetical protein 0.0215 0.0651 0.0647
Schistosoma mansoni ephrin receptor 0.0092 0.008 0.0119
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0097 0.0104 0.0099
Onchocerca volvulus 0.0326 0.1166 0.1293
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0145 0.0646
Plasmodium falciparum calcium-dependent protein kinase 3 0.0139 0.0299 0.1235
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0331 0.1191 0.1186
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Giardia lamblia Kinase, CK1 Casein kinase 0.0162 0.0405 0.1494
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0521 0.2075 0.2819
Leishmania major protein kinase A catalytic subunit isoform 2 0.0168 0.0435 0.2094
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0631 0.0995
Schistosoma mansoni tyrosine kinase 0.0489 0.1925 0.3049
Schistosoma mansoni tyrosine kinase 0.0563 0.2271 0.3599
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0368 0.1664
Trypanosoma brucei rac serine-threonine kinase, putative 0.0548 0.22 1
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0183 0.0501 0.0496
Echinococcus granulosus tyrosine protein kinase HCK 0.0218 0.0667 0.0746
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0501 0.2268
Schistosoma mansoni serine/threonine protein kinase 0.0478 0.1873 0.2966
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0331 0.1492
Entamoeba histolytica casein kinase, putative 0.0162 0.0405 0.1841
Trypanosoma brucei protein kinase, putative 0.0239 0.0762 0.3451
Brugia malayi Protein kinase domain containing protein 0.0106 0.0145 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0631 0.0995
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0007 0.0004
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0291 0.1005 0.1
Schistosoma mansoni glutaminase 0.033 0.1186 0.1876
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0237 0.0756 0.0845
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.012 0.0209 0.0325
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0239 0.0762 0.1032
Loa Loa (eye worm) hypothetical protein 0.011 0.0163 0.0158
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0342 0.0338
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0154 0.0368 0.0364
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0152 0.036 0.1728
Echinococcus granulosus unc 13 munc13 0.0108 0.0153 0.0167
Mycobacterium ulcerans glutaminase 0.033 0.1186 1
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0146 0.0331 0.0367
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0179 0.0486 0.0764
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.015 0.0351 0.1687
Loa Loa (eye worm) RasGEF domain-containing protein 0.0105 0.0141 0.0137
Echinococcus multilocularis dual specificity protein kinase clk2 0.0168 0.0435 0.0586
Trypanosoma cruzi cdc2-related kinase 3 0.0219 0.0672 0.325
Echinococcus multilocularis lachesin 0.011 0.0163 0.0216
Echinococcus granulosus tyrosine protein kinase ABL1 0.0557 0.224 0.2517
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0137 0.0611
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.0658 0.1037
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0326 0.1165 0.1161
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0436 0.1679 0.1885
Plasmodium vivax calcium-dependent protein kinase, putative 0.0139 0.0299 0.1759
Giardia lamblia Kinase, AGC AKT 0.0216 0.0656 0.2787
Schistosoma mansoni netrin receptor unc5 0.0085 0.0045 0.0064
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.015 0.0351 0.1687
Onchocerca volvulus 0.0149 0.0342 0.0376
Echinococcus granulosus myotubularin protein 13 0.0118 0.0201 0.0221
Brugia malayi Protein kinase domain containing protein 0.0575 0.2325 0.2321
Trichomonas vaginalis glutaminase, putative 0.033 0.1186 0.5387
Echinococcus multilocularis NCK adaptor protein 0.0127 0.0241 0.0321
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0292 0.1009 0.1367
Schistosoma mansoni serine/threonine protein kinase 0.0478 0.1873 0.2966
Schistosoma mansoni protein kinase 0.0436 0.1679 0.2658
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0118 0.02 0.022
Echinococcus granulosus tyrosine protein kinase Srms 0.0547 0.2195 0.2466
Trypanosoma cruzi casein kinase, putative 0.0162 0.0405 0.1949
Onchocerca volvulus 0.0126 0.0238 0.0259
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0326 0.1165 0.1161
Schistosoma mansoni hypothetical protein 0.012 0.0209 0.0325
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0168 0.0435 0.196
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0163 0.0158
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0005 0.0009
Echinococcus granulosus contactin 0.0128 0.0246 0.0271
Leishmania major protein kinase, putative 0.0152 0.036 0.1728
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0501 0.2268
Schistosoma mansoni tyrosine kinase 0.0413 0.1572 0.2488
Echinococcus granulosus serine:threonine protein kinase N2 0.0419 0.1598 0.1794
Echinococcus granulosus N chimaerin 0.0179 0.0486 0.0542
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0436 0.1679 0.228
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0145 0.0222
Echinococcus multilocularis myotubularin protein 13 0.0118 0.0201 0.0267
Loa Loa (eye worm) TK protein kinase 0.0293 0.1012 0.1008
Loa Loa (eye worm) hypothetical protein 0.0451 0.1749 0.1745
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0435 0.1966
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0139 0.0299 0.1759
Echinococcus multilocularis tyrosine protein kinase Src42A 0.022 0.0675 0.0913
Echinococcus multilocularis casein kinase I alpha 0.0162 0.0405 0.0545
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0131 0.026 0.0287
Giardia lamblia Kinase, STE STE20 0.0152 0.036 0.1261
Echinococcus granulosus serine:threonine protein kinase MARK2 0.037 0.1374 0.1541
Loa Loa (eye worm) TK/EPH protein kinase 0.0235 0.0744 0.074
Echinococcus multilocularis rac serine:threonine kinase 0.0307 0.1078 0.1461
Brugia malayi Protein kinase domain containing protein 0.0149 0.0342 0.0338
Schistosoma mansoni serine/threonine-protein kinase 0.0307 0.1078 0.1704
Echinococcus multilocularis tyrosine protein kinase 0.0309 0.1087 0.1474
Schistosoma mansoni tyrosine kinase 0.0343 0.1247 0.1973
Echinococcus multilocularis tyrosine protein kinase otk 0.011 0.0163 0.0216
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Loa Loa (eye worm) hypothetical protein 0.0125 0.0232 0.0227
Brugia malayi Immunoglobulin I-set domain containing protein 0.0122 0.0219 0.0214
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.01 0.0115 0.011
Onchocerca volvulus Tyrosine kinase homolog 0.2008 0.8988 1
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0501 0.2268
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0216 0.0658 0.0653
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0457 0.1778 0.1774
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0168 0.0435 0.2094
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0436 0.1679 0.7631
Loa Loa (eye worm) TK/EGFR protein kinase 0.0837 0.3545 0.3542
Toxoplasma gondii CMGC kinase, CK2 family 0.0183 0.0501 0.2324
Loa Loa (eye worm) casein kinase 0.0176 0.0471 0.0466
Echinococcus multilocularis serine threonine protein kinase 0.0372 0.1383 0.1877
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0097 0.0105 0.0469
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0465 0.1812 0.2034
Trypanosoma brucei polo-like protein kinase 0.0518 0.2058 0.9354
Entamoeba histolytica casein kinase, putative 0.0183 0.0501 0.2278
Loa Loa (eye worm) hypothetical protein 0.0105 0.0141 0.0137
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0152 0.036 0.1635
Plasmodium falciparum NIMA related kinase 1 0.0254 0.0831 0.4611
Echinococcus granulosus NDR protein kinase 0.0292 0.1009 0.113
Loa Loa (eye worm) hypothetical protein 0.0237 0.0756 0.0751
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0521 0.2075 0.2071
Trypanosoma cruzi p21-activated kinase 3, putative 0.0093 0.0085 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.1378 0.218
Echinococcus granulosus tumor protein p63 0.0389 0.1458 0.1636
Giardia lamblia Kinase, CAMK CAMKL 0.0128 0.0247 0.0682
Trypanosoma brucei protein kinase, putative 0.015 0.0351 0.1578
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0128 0.0247 0.0273
Brugia malayi Temporarily assigned gene name protein 59 0.012 0.0209 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0247 0.0385
Trichomonas vaginalis STE family protein kinase 0.0155 0.0372 0.168
Trypanosoma brucei aurora B kinase 0.0436 0.1679 0.7626
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0491 0.1935 0.1931
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Echinococcus multilocularis cyclin dependent kinase 1 0.0219 0.0672 0.0909
Echinococcus multilocularis mitogen activated protein kinase 0.015 0.0351 0.0472
Trichomonas vaginalis STE family protein kinase 0.0155 0.0372 0.168
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0168 0.0435 0.2094
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0331 0.1492
Loa Loa (eye worm) hypothetical protein 0.0078 0.0012 0.0007
Onchocerca volvulus 0.0122 0.0219 0.0238
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0501 0.2268
Echinococcus granulosus protein kinase c eta type 0.0105 0.0141 0.0154
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.015 0.0351 0.1578
Brugia malayi Immunoglobulin I-set domain containing protein 0.0518 0.2061 0.2058
Echinococcus granulosus lachesin 0.011 0.0163 0.0178
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0442 0.1709 0.1705
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0125 0.0232 0.0227
Echinococcus granulosus Immunoglobulin 0.0215 0.0651 0.0728
Schistosoma mansoni tyrosine kinase 0.0647 0.2659 0.4215
Brugia malayi hypothetical protein 0.0149 0.0342 0.0338
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0605 0.2464 0.246
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0155 0.0372 0.0413
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0518 0.2058 0.2796
Brugia malayi Fibronectin type III domain containing protein 0.0233 0.0733 0.0729
Onchocerca volvulus 0.0339 0.1226 0.136
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.037 0.1374 0.1864
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0125 0.0232 0.0227
Entamoeba histolytica protein kinase domain containing protein 0.0125 0.0233 0.1057
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0435 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0435 0.0683
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Echinococcus multilocularis calcium activated potassium channel 0.0211 0.0631 0.0853
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.026 0.117
Echinococcus multilocularis cyclin dependent kinase 1 0.0219 0.0672 0.0909
Echinococcus multilocularis aurora kinase A 0.0436 0.1679 0.228
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0294 0.1018 0.138
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0155 0.0372 0.0413
Schistosoma mansoni serine/threonine protein kinase 0.0179 0.0483 0.0759
Brugia malayi Peroxidasin 0.0111 0.0166 0.0161
Echinococcus granulosus tyrosine protein kinase otk 0.011 0.0163 0.0178
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0125 0.0232 0.036
Schistosoma mansoni unc-13 (munc13) 0.0108 0.0153 0.0235
Entamoeba histolytica hypothetical protein 0.0105 0.0141 0.0643
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0567 0.2286 0.2282
Entamoeba histolytica protein kinase domain containing protein 0.0183 0.0501 0.2278
Echinococcus multilocularis myosin iiia 0.0152 0.036 0.0483
Loa Loa (eye worm) hypothetical protein 0.0273 0.0922 0.0917
Leishmania major protein kinase, putative 0.0168 0.0435 0.2095
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0351 0.1586
Echinococcus multilocularis casein kinase ii subunit alpha 0.0183 0.0501 0.0676
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0368 0.1664
Brugia malayi Serine/threonine-protein kinase SULU 0.0236 0.0747 0.0742
Schistosoma mansoni protein kinase 0.0465 0.1813 0.2871
Entamoeba histolytica protein kinase, putative 0.0142 0.0311 0.1413
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.011 0.0163 0.0158
Loa Loa (eye worm) AGC/PKA protein kinase 0.0168 0.0435 0.043
Brugia malayi Protein kinase c protein 2 0.0236 0.0751 0.0746
Brugia malayi Protein kinase domain containing protein 0.0168 0.0435 0.043
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0146 0.0331 0.0326
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0342 0.0338
Brugia malayi Protein kinase domain containing protein 0.0309 0.1087 0.1083
Entamoeba histolytica protein kinase, putative 0.0548 0.22 1
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0254 0.0831 0.4934
Entamoeba histolytica PH domain containing protein kinase, putative 0.0181 0.0495 0.2248
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0405 0.0635
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.1005 0.4558
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0518 0.2058 1
Echinococcus granulosus hypothetical protein 0.0118 0.02 0.022
Echinococcus granulosus Diacylglycerol kinase theta 0.0105 0.0141 0.0154
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0168 0.0433 0.0428
Loa Loa (eye worm) hypothetical protein 0.021 0.0629 0.0625
Loa Loa (eye worm) hypothetical protein 0.0233 0.0733 0.0729
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0139 0.0299 0.0295
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0027 0.0122
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0168 0.0435 0.1959
Entamoeba histolytica protein kinase, putative 0.0112 0.0174 0.0789
Trypanosoma cruzi casein kinase, putative 0.0162 0.0405 0.1949
Brugia malayi Protein kinase domain containing protein 0.0146 0.0331 0.0326
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0128 0.0247 0.118
Echinococcus granulosus mitogen activated protein kinase 14 0.0299 0.1041 0.1167
Onchocerca volvulus 0.0239 0.0762 0.0843
Onchocerca volvulus 0.0162 0.0405 0.0445
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0368 0.1664
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0431 0.1655 0.1858
Onchocerca volvulus 0.0111 0.017 0.0184
Loa Loa (eye worm) hypothetical protein 0.0108 0.0153 0.0148
Brugia malayi serine/threonine-protein kinase PAK 7 0.0442 0.1709 0.1705
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.184 0.8204 0.8204
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0168 0.0435 0.0586
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0465 0.1813 0.2036
Trichomonas vaginalis STE family protein kinase 0.0155 0.0372 0.168
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0299 0.1041 0.5047
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0605 0.2464 0.246
Onchocerca volvulus 0.0575 0.2325 0.2583
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0351 0.1586
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0521 0.2075 0.2331
Schistosoma mansoni vam6/vps39 related 0.012 0.0209 0.0325
Echinococcus granulosus protein kinase c iota type 0.056 0.2257 0.2536
Schistosoma mansoni unc-13 (munc13) 0.0108 0.0153 0.0235
Loa Loa (eye worm) hypothetical protein 0.0183 0.0504 0.05
Trichomonas vaginalis CAMK family protein kinase 0.0518 0.2058 0.9354
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0152 0.036 0.1728
Schistosoma mansoni tyrosine kinase 0.0647 0.2659 0.4215
Echinococcus multilocularis casein kinase I gamma 0.0227 0.0706 0.0955
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.082 0.0816
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0236 0.0747 0.101
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.026 0.117
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0128 0.0247 0.033
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0219 0.0672 0.3125
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.017 0.0444 0.0495
Loa Loa (eye worm) hypothetical protein 0.0176 0.0469 0.0464
Schistosoma mansoni protein kinase C 0.0108 0.0153 0.0235
Echinococcus granulosus mitogen activated protein kinase 3 0.015 0.0351 0.039
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0501 0.2268
Brugia malayi serine/threonine kinase 12 0.0436 0.1679 0.1675
Brugia malayi Protein kinase domain containing protein 0.0149 0.0342 0.0338
Leishmania major protein kinase A catalytic subunit isoform 1 0.0168 0.0435 0.2094
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0672 0.106
Onchocerca volvulus 0.0149 0.0342 0.0376
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0435 0.0683
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0005 0.0009
Giardia lamblia Kinase, AGC PKA 0.0168 0.0435 0.1648
Loa Loa (eye worm) hypothetical protein 0.0105 0.0141 0.0137
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0139 0.0299 0.1379
Loa Loa (eye worm) hypothetical protein 0.0128 0.0246 0.0241
Toxoplasma gondii casein kinase I 0.0162 0.0405 0.1874
Schistosoma mansoni serine/threonine protein kinase 0.1021 0.4396 0.6973
Echinococcus multilocularis neuroglian 0.0269 0.0901 0.122
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.2003 0.3173
Loa Loa (eye worm) hypothetical protein 0.0168 0.0435 0.043
Schistosoma mansoni tyrosine kinase 0.0357 0.1313 0.2077
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0518 0.2058 0.2054
Brugia malayi Protein kinase domain containing protein 0.0227 0.0706 0.0701
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0005 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0292 0.1009 0.4578
Loa Loa (eye worm) hypothetical protein 0.0212 0.0639 0.0635
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0215 0.0651 0.088
Echinococcus multilocularis expressed protein 0.01 0.0115 0.0149
Echinococcus granulosus insulin receptor 0.0647 0.2659 0.2988
Onchocerca volvulus 0.0149 0.0342 0.0376
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0162 0.0405 0.1949
Loa Loa (eye worm) hypothetical protein 0.0078 0.0012 0.0007
Trypanosoma cruzi polo-like protein kinase, putative 0.0518 0.2058 1
Loa Loa (eye worm) transcription factor SMAD2 0.0247 0.0802 0.0798
Brugia malayi protein kinase C II. 0.04 0.151 0.1506
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0139 0.0299 0.0295
Echinococcus granulosus dual specificity 0.0226 0.0704 0.0787
Trichomonas vaginalis CMGC family protein kinase 0.0219 0.0672 0.3046
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0128 0.0247 0.118
Echinococcus granulosus roundabout 2 0.0128 0.0246 0.0271
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0292 0.1009 0.1367
Loa Loa (eye worm) hypothetical protein 0.011 0.0163 0.0158
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0368 0.1664
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0371 0.1378 0.1545
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0152 0.036 0.1635
Onchocerca volvulus 0.0105 0.014 0.0151
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0168 0.0435 0.0586
Schistosoma mansoni serine/threonine kinase 0.0292 0.1009 0.1594
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0139 0.0299 0.1379
Loa Loa (eye worm) CAMK protein kinase 0.0122 0.0219 0.0214
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0381 0.1422 0.193
Schistosoma mansoni protein kinase 0.0112 0.0174 0.0268
Schistosoma mansoni tyrosine kinase 0.0184 0.0509 0.0801
Loa Loa (eye worm) CDC7 protein kinase 0.0106 0.0145 0.014
Trichomonas vaginalis AGC family protein kinase 0.0436 0.1679 0.7628
Loa Loa (eye worm) hypothetical protein 0.0126 0.0238 0.0233
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0246 0.0241
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.021 0.0629 0.0625
Onchocerca volvulus Serine\/threonine kinase homolog 0.0179 0.0483 0.0532
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0163 0.0158
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0343 0.1247 0.1692
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0139 0.0299 0.1379
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.015 0.0351 0.1622
Trypanosoma cruzi aurora B kinase, putative 0.0436 0.1679 0.8153
Plasmodium falciparum calcium-dependent protein kinase 5 0.0139 0.0299 0.1235
Loa Loa (eye worm) hypothetical protein 0.0176 0.0469 0.0464
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0236 0.0747 0.0742
Loa Loa (eye worm) hypothetical protein 0.0273 0.0922 0.0917
Echinococcus multilocularis serine:threonine protein kinase 0.021 0.0629 0.085
Schistosoma mansoni titin 0.0122 0.0219 0.0339
Echinococcus multilocularis rho associated protein kinase 0.0626 0.256 0.348
Echinococcus granulosus casein kinase I delta 0.0162 0.0405 0.045
Loa Loa (eye worm) RNA binding protein 0.0076 0.0007 0.0002
Echinococcus multilocularis tyrosine protein kinase shark 0.0357 0.1313 0.1781
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0168 0.0435 0.0484
Brugia malayi STE20-like kinase MST 0.0491 0.1935 0.1931
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0261 0.0867 0.3932
Leishmania major casein kinase, putative 0.0162 0.0405 0.1949
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0168 0.0435 0.1959
Echinococcus granulosus protein kinase shaggy 0.0239 0.0762 0.0853
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0239 0.0762 0.0758
Echinococcus granulosus titin 0.0122 0.0219 0.0241
Echinococcus multilocularis death associated protein kinase 1 0.1655 0.7348 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.0141 0.0137
Echinococcus multilocularis casein kinase I delta 0.0162 0.0405 0.0545
Echinococcus granulosus serine:threonine kinase SAD 1 0.0128 0.0247 0.0273
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0485 0.1908 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0227 0.0706 0.0701
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0152 0.036 0.1616
Plasmodium vivax protein kinase Crk2 0.0219 0.0672 0.3986
Echinococcus multilocularis tyrosine protein kinase Blk 0.0293 0.1012 0.1372
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.1422 0.2251
Echinococcus multilocularis c src tyrosine kinase 0.0199 0.0578 0.078
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0168 0.0435 0.1959
Echinococcus granulosus serine/threonine protein kinase 0.0307 0.1078 0.1208
Leishmania major protein kinase A catalytic subunit 0.0168 0.0435 0.2094
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0226 0.0704 0.3403
Trichomonas vaginalis STE family protein kinase 0.0112 0.0174 0.0777
Entamoeba histolytica tyrosin kinase, putative 0.0081 0.0027 0.0122
Loa Loa (eye worm) hypothetical protein 0.0128 0.0247 0.0242
Entamoeba histolytica p21-activated kinase 0.0168 0.0432 0.1963
Trichomonas vaginalis CAMK family protein kinase 0.021 0.0629 0.2851
Mycobacterium ulcerans hypothetical protein 0.0099 0.0114 0.092
Onchocerca volvulus Basement membrane proteoglycan homolog 0.011 0.0163 0.0176
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0111 0.017 0.0805
Trichomonas vaginalis CAMK family protein kinase 0.0234 0.0742 0.3362
Schistosoma mansoni rap gtpase-activating protein 0.012 0.0209 0.0325
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0436 0.1679 0.7631
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.012 0.0209 0.0325
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0343 0.1247 0.1692
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0342 0.0338
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0462 0.1798 0.2442
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0216 0.0658 0.0653
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0168 0.0435 0.2095
Echinococcus multilocularis roundabout 2 0.0128 0.0246 0.0328
Brugia malayi casein kinase 1, delta 0.0162 0.0405 0.04
Plasmodium falciparum calcium-dependent protein kinase 1 0.0139 0.0299 0.1235
Trichomonas vaginalis CMGC family protein kinase 0.0168 0.0435 0.1967
Brugia malayi Egg laying defective protein 4 0.015 0.0349 0.0344
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0141 0.0643
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0271 0.0913 0.1022
Loa Loa (eye worm) TK/ROR protein kinase 0.0128 0.0247 0.0242
Schistosoma mansoni tyrosine kinase 0.0199 0.0578 0.0909
Brugia malayi Protein kinase domain containing protein 0.01 0.0115 0.011
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0226 0.0704 0.0699
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0078 0.0015 0.0013
Echinococcus granulosus aurora kinase A 0.0436 0.1679 0.1885
Brugia malayi intracellular kinase 0.0239 0.0762 0.0758
Brugia malayi P38 map kinase family protein 2 0.0299 0.1041 0.1037
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.015 0.0351 0.1687
Loa Loa (eye worm) hypothetical protein 0.023 0.0723 0.0719
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0132 0.0127
Echinococcus granulosus growth factor receptor bound protein 2 0.0127 0.0241 0.0265
Brugia malayi C1-like domain containing protein 0.0376 0.1401 0.1397
Giardia lamblia Kinase, AGC PKA 0.0294 0.1018 0.465
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0168 0.0435 0.2014
Giardia lamblia Kinase, CMGC CDK 0.0219 0.0672 0.2869
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0349 0.0546
Echinococcus granulosus protein kinase C gamma type 0.0372 0.1383 0.1552
Loa Loa (eye worm) hypothetical protein 0.011 0.0163 0.0158
Echinococcus multilocularis netrin receptor unc 5 0.0085 0.0045 0.0055
Echinococcus granulosus tyrosine protein kinase 0.0309 0.1087 0.1219
Plasmodium falciparum glycogen synthase kinase 3 0.0239 0.0762 0.4177
Entamoeba histolytica cell division protein kinase 2, putative 0.0219 0.0672 0.3055
Echinococcus multilocularis casein kinase I alpha 0.0162 0.0405 0.0545
Echinococcus multilocularis protein kinase shaggy 0.0239 0.0762 0.1032
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.1009 0.1594
Schistosoma mansoni kinase 0.0554 0.2227 0.3529
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0246 0.0241
Giardia lamblia Kinase, CAMK CAMKL 0.0128 0.0247 0.0682
Brugia malayi casein kinase I 0.0162 0.0405 0.04
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0163 0.0158
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0343 0.1247 0.1692
Echinococcus granulosus protein tyrosine kinase 0.0569 0.2298 0.2581
Plasmodium vivax glycogen synthase kinase 3, putative 0.0239 0.0762 0.4525
Trichomonas vaginalis CMGC family protein kinase 0.0219 0.0672 0.3046
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0125 0.0233 0.1109
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0294 0.1018 0.4935
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0128 0.0246 0.0328
Entamoeba histolytica protein kinase, putative 0.0125 0.0231 0.1052
Schistosoma mansoni titin 0.011 0.0163 0.0251
Loa Loa (eye worm) hypothetical protein 0.0118 0.0201 0.0196
Echinococcus multilocularis serine:threonine protein kinase 38 0.0292 0.1009 0.1367
Giardia lamblia Kinase, PLK 0.0518 0.2058 1
Echinococcus multilocularis Immunoglobulin 0.0215 0.0651 0.088
Plasmodium vivax serine/threonine kinase-1, putative 0.0168 0.0435 0.257
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0163 0.0158
Trypanosoma cruzi cdc2-related kinase 1 0.0219 0.0672 0.325
Trichomonas vaginalis CK1 family protein kinase 0.0162 0.0405 0.183
Schistosoma mansoni protein kinase 0.0465 0.1813 0.2871
Echinococcus multilocularis protein tyrosine kinase 0.0569 0.2298 0.3122
Brugia malayi protein unc-22 0.0122 0.0219 0.0214
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0141 0.0643
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0139 0.0299 0.0295
Echinococcus granulosus tyrosine protein kinase Blk 0.0293 0.1012 0.1134
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0342 0.0338
Echinococcus granulosus casein kinase ii subunit alpha 0.0183 0.0501 0.0559
Schistosoma mansoni atypical protein kinase C 0.0572 0.2313 0.3665
Schistosoma mansoni adapter molecule crk 0.0125 0.0232 0.036
Giardia lamblia Kinase, CMGC CK2 0.0183 0.0501 0.1989
Trichomonas vaginalis CK1 family protein kinase 0.0162 0.0405 0.183
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0435 0.0683
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0125 0.0233 0.1109
Echinococcus multilocularis cGMP dependent protein kinase 1 0.015 0.0349 0.0468
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0139 0.0299 0.0332
Entamoeba histolytica protein kinase, putative 0.0218 0.0667 0.3034
Echinococcus multilocularis raf serine:threonine protein kinase 0.1021 0.4396 0.598
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0343 0.1247 0.1692
Onchocerca volvulus 0.0106 0.0145 0.0156
Entamoeba histolytica protein kinase, putative 0.0226 0.0704 0.3198
Echinococcus multilocularis mitogen activated protein kinase 14 0.0299 0.1041 0.1411
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0215 0.0651 0.1026
Brugia malayi Pre-SET motif family protein 0.0251 0.082 0.0816
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0271 0.091 0.1019
Schistosoma mansoni protein kinase C mu 0.0376 0.1401 0.2218
Schistosoma mansoni serine/threonine kinase 0.0291 0.1005 0.1587
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0085 0.0127
Trichomonas vaginalis STE family protein kinase 0.0155 0.0372 0.168
Echinococcus granulosus cGMP dependent protein kinase 1 0.015 0.0349 0.0387
Onchocerca volvulus 0.0626 0.256 0.2845
Giardia lamblia Kinase, NEK 0.0254 0.0831 0.3685
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0518 0.2058 0.2312
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.037 0.1374 0.2174
Schistosoma mansoni tyrosine kinase 0.0465 0.1812 0.2869
Schistosoma mansoni hypothetical protein 0.0105 0.0141 0.0217
Plasmodium falciparum casein kinase 2, alpha subunit 0.0183 0.0501 0.2517
Loa Loa (eye worm) hypothetical protein 0.0371 0.1375 0.1371
Echinococcus multilocularis tyrosine protein kinase Abl 0.0355 0.1303 0.1768
Brugia malayi Raf kinase 0.0915 0.3907 0.3904
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0247 0.0385
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0162 0.0405 0.04
Schistosoma mansoni cell adhesion molecule 0.0128 0.0246 0.0382
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0108 0.0153 0.0167
Trichomonas vaginalis AGC family protein kinase 0.0436 0.1679 0.7628
Entamoeba histolytica hypothetical protein 0.0226 0.0704 0.3198
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Brugia malayi Tyrosine-protein kinase abl-1 0.0252 0.0824 0.082
Loa Loa (eye worm) AGC/PKG protein kinase 0.015 0.0349 0.0344
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0318 0.1129 0.1531
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0139 0.0299 0.0401
Brugia malayi TAR-binding protein 0.0076 0.0007 0.0002
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0139 0.0299 0.0401
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0342 0.0338
Echinococcus multilocularis roundabout 2 0.0128 0.0246 0.0328
Echinococcus granulosus Vam6:Vps39 protein 0.012 0.0209 0.023
Echinococcus granulosus serine:threonine protein kinase MARK2 0.037 0.1374 0.1541
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.015 0.0351 0.1687
Loa Loa (eye worm) AGC/PKA protein kinase 0.0168 0.0435 0.043
Trichomonas vaginalis AGC family protein kinase 0.0548 0.22 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0219 0.0672 0.0668
Brugia malayi cell division control protein 2 homolog 0.0219 0.0672 0.0668
Echinococcus granulosus roundabout 2 0.0343 0.1245 0.1396
Plasmodium falciparum protein kinase, putative 0.0125 0.0233 0.081
Toxoplasma gondii aurora kinase 0.0436 0.1679 0.7839
Schistosoma mansoni nephrin 0.0128 0.0246 0.0382
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0139 0.0299 0.0332
Echinococcus granulosus tar DNA binding protein 0.0076 0.0007 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.1129 0.1785
Trichomonas vaginalis AGC family protein kinase 0.0312 0.1102 0.5001
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0502 0.1984 0.2228
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0216 0.0656 0.0652
Trichomonas vaginalis CAMK family protein kinase 0.0518 0.2058 0.9354
Trichomonas vaginalis AGC family protein kinase 0.0548 0.22 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.017 0.0444 0.0598
Trypanosoma brucei cdc2-related kinase 3 0.0219 0.0672 0.304
Echinococcus multilocularis protein kinase c eta type 0.0105 0.0141 0.0186
Loa Loa (eye worm) hypothetical protein 0.0325 0.1163 0.1158
Brugia malayi Protein kinase domain containing protein 0.0149 0.0342 0.0338
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0128 0.0246 0.0382
Brugia malayi map kinase activated protein kinase protein 2 0.0762 0.3192 0.3189
Echinococcus multilocularis tumor protein p63 0.0389 0.1458 0.1979
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0125 0.0233 0.0311
Loa Loa (eye worm) hypothetical protein 0.0605 0.2464 0.246
Trichomonas vaginalis AGC family protein kinase 0.0548 0.22 1
Echinococcus granulosus Rac GTPase activating protein 1 0.0105 0.0141 0.0154
Echinococcus granulosus c-Jun N-terminal kinases 0.0506 0.2003 0.225
Trypanosoma cruzi casein kinase, putative 0.0162 0.0405 0.1949
Entamoeba histolytica protein kinase 2, putative 0.0294 0.1018 0.4628
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0122 0.0219 0.0214
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0216 0.0658 0.0889
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.0355 0.035
Schistosoma mansoni tyrosine kinase 0.0837 0.3545 0.5622
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0457 0.1775 0.1771
Echinococcus granulosus cyclin dependent kinase 0.0219 0.0672 0.0751
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0465 0.1812 0.2461
Entamoeba histolytica protein kinase domain containing protein 0.0239 0.0762 0.3466
Echinococcus granulosus casein kinase i 0.0162 0.0405 0.045
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0762 0.3192 0.3189
Echinococcus multilocularis CDC7 cell division cycle 7 0.0106 0.0145 0.0191
Echinococcus multilocularis 0.0234 0.0741 0.1002
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0368 0.1664
Entamoeba histolytica protein kinase, putative 0.0292 0.1009 0.4585
Echinococcus granulosus dual specificity 0.0154 0.0368 0.0409
Schistosoma mansoni hypothetical protein 0.0103 0.0132 0.0202
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0376 0.1401 0.1397
Echinococcus granulosus hemicentin 1 0.011 0.0163 0.0178
Toxoplasma gondii AGC kinase 0.0535 0.214 1
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0093 0.0085 0.0374
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0183 0.0501 0.2964
Loa Loa (eye worm) hypothetical protein 0.0233 0.0733 0.0729
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0108 0.0153 0.0202
Echinococcus multilocularis serine:threonine protein kinase 0.021 0.0629 0.085
Schistosoma mansoni protein kinase C mu 0.0105 0.0141 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0233 0.0363
Brugia malayi RhoGEF domain containing protein 0.0105 0.0141 0.0137
Schistosoma mansoni protein kinase 0.0207 0.0613 0.0966
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0146 0.0331 0.0444
Plasmodium falciparum serine/threonine protein kinase KIN 0.0128 0.0247 0.0903
Loa Loa (eye worm) hypothetical protein 0.0169 0.0437 0.0433
Brugia malayi Protein kinase domain containing protein 0.0292 0.1009 0.1004
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0179 0.0486 0.0542
Onchocerca volvulus 0.0106 0.0145 0.0156
Onchocerca volvulus 0.012 0.0209 0.0228
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0502 0.1984 0.2695
Echinococcus multilocularis hypothetical protein 0.016 0.0396 0.0533
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0105 0.0141 0.0137
Echinococcus multilocularis nervana 2 0.0243 0.0783 0.106
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0239 0.0762 0.3548
Onchocerca volvulus 0.0149 0.0342 0.0376
Schistosoma mansoni serine/threonine protein kinase 0.037 0.1374 0.2174
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0388 0.1453 0.1631
Echinococcus multilocularis unc 13 (munc13) 0.0108 0.0153 0.0202
Toxoplasma gondii diacylglycerol kinase, putative 0.0105 0.0141 0.0639
Echinococcus granulosus protein kinase c epsilon type 0.04 0.151 0.1694
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0343 0.1247 0.1692
Loa Loa (eye worm) SRC-1 0.0343 0.1247 0.1243
Plasmodium falciparum protein serine/threonine kinase-1 0.0168 0.0435 0.2097
Loa Loa (eye worm) hypothetical protein 0.022 0.0677 0.0672
Brugia malayi serine/threonine-protein kinase 6 0.0436 0.1679 0.1675
Brugia malayi Protein kinase domain containing protein 0.0457 0.1775 0.1771
Echinococcus multilocularis cyclin dependent kinase 5 0.0219 0.0672 0.0909
Trypanosoma cruzi cdc2-related kinase 3 0.0219 0.0672 0.325
Trichomonas vaginalis STE family protein kinase 0.0254 0.0831 0.3768
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Brugia malayi Protein kinase domain containing protein 0.0207 0.0613 0.0609
Echinococcus multilocularis dual specificity 0.0154 0.0368 0.0495
Loa Loa (eye worm) TK/INSR protein kinase 0.0647 0.2659 0.2655
Brugia malayi Protein kinase domain containing protein 0.039 0.1465 0.1461
Loa Loa (eye worm) hypothetical protein 0.0339 0.1226 0.1222
Echinococcus multilocularis insulin receptor 0.0647 0.2659 0.3614
Schistosoma mansoni cell adhesion molecule 0.011 0.0163 0.0251
Loa Loa (eye worm) hypothetical protein 0.0378 0.1411 0.1407
Schistosoma mansoni tyrosine kinase 0.0136 0.0285 0.0444
Entamoeba histolytica protein kinase, putative 0.01 0.0115 0.0521
Brugia malayi RNA binding protein 0.0076 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.012 0.0209 0.0205
Entamoeba histolytica protein kinase, putative 0.0125 0.0233 0.1061
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0226 0.0704 0.3183
Brugia malayi Protein kinase domain containing protein 0.0179 0.0483 0.0478
Echinococcus granulosus dual specificity protein kinase clk2 0.0168 0.0435 0.0484
Mycobacterium leprae Probable lipase LipE 0.0076 0.0005 0.5
Echinococcus multilocularis 0.0118 0.02 0.0266
Brugia malayi Kinase associated domain 1 family protein 0.016 0.0396 0.0392
Plasmodium vivax serine/threonine protein kinase, putative 0.01 0.0115 0.0655
Brugia malayi protein kinase C3,putative 0.0319 0.1135 0.1131
Echinococcus granulosus cGMP dependent protein kinase 0.015 0.0349 0.0387
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0199 0.0578 0.0909
Brugia malayi Protein kinase domain containing protein 0.021 0.0629 0.0625
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0209 0.0932
Trypanosoma cruzi polo-like protein kinase, putative 0.0518 0.2058 1
Echinococcus multilocularis epidermal growth factor receptor 0.0837 0.3545 0.4821
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0457 0.1778 0.1997
Echinococcus granulosus peroxidasin 0.0111 0.0166 0.0181
Plasmodium vivax unspecified product 0.0183 0.0501 0.2964
Loa Loa (eye worm) AGC/PKN protein kinase 0.0419 0.1598 0.1594
Plasmodium vivax tyrosine kinase-like protein, putative 0.0097 0.0105 0.0598
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0462 0.1798 0.2019
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0136 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.1378 0.218
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0162 0.0405 0.04
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0128 0.0246 0.0328
Trypanosoma brucei Casein kinase II 0.0183 0.0501 0.2261
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.04 0.151 0.1506
Schistosoma mansoni serine/threonine protein kinase 0.0521 0.2075 0.3288
Loa Loa (eye worm) hypothetical protein 0.0565 0.2279 0.2275
Loa Loa (eye worm) hypothetical protein 0.012 0.0209 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.0457 0.1778 0.2816
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0219 0.0672 0.0668
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0762 0.3192 0.434
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0168 0.0435 0.0484
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0168 0.0435 0.043
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0226 0.0704 0.3403
Echinococcus granulosus Protein kinase C brain isozyme 0.0478 0.1873 0.2103
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0381 0.1422 0.1595
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0179 0.0483 0.065
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0563 0.2271 0.2551
Entamoeba histolytica protein kinase domain containing protein 0.0154 0.0368 0.1675
Loa Loa (eye worm) hypothetical protein 0.016 0.0396 0.0392
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Giardia lamblia Kinase, NEK 0.0254 0.0831 0.3685
Entamoeba histolytica protein kinase, putative 0.0146 0.0331 0.1503
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1987 0.8887 1
Schistosoma mansoni cell adhesion molecule 0.0289 0.0995 0.1573
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0178 0.048 0.0476
Echinococcus multilocularis serine:threonine protein kinase N2 0.0127 0.0241 0.0321
Echinococcus granulosus epidermal growth factor receptor 0.0563 0.2271 0.2551
Echinococcus granulosus CDC7 cell division cycle 7 0.0106 0.0145 0.0158
Loa Loa (eye worm) hypothetical protein 0.0078 0.0015 0.001
Echinococcus granulosus tyrosine protein kinase Src42A 0.0343 0.1247 0.1399
Schistosoma mansoni serine/threonine protein kinase 0.0626 0.256 0.4058
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0219 0.0672 0.325
Brugia malayi MAP kinase sur-1 0.015 0.0351 0.0347
Brugia malayi Protein kinase domain containing protein 0.0521 0.2075 0.2071
Echinococcus multilocularis serine:threonine protein kinase N2 0.0419 0.1598 0.2169
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0465 0.1813 0.2462
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0349 0.0546
Trypanosoma cruzi casein kinase II, putative 0.0183 0.0501 0.2417
Brugia malayi serine/threonine protein kinase 6 0.0436 0.1679 0.1675
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0247 0.0385
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0343 0.1247 0.1399
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.011 0.0163 0.0251
Loa Loa (eye worm) hypothetical protein 0.011 0.0163 0.0158
Loa Loa (eye worm) hypothetical protein 0.0149 0.0342 0.0338
Schistosoma mansoni tyrosine kinase 0.0569 0.2298 0.3641
Loa Loa (eye worm) hypothetical protein 0.0234 0.074 0.0736
Trichomonas vaginalis CAMK family protein kinase 0.0518 0.2058 0.9354
Loa Loa (eye worm) hypothetical protein 0.0325 0.1163 0.1158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0246 0.0241
Schistosoma mansoni diacylglycerol kinase theta 0.0105 0.0141 0.0217
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0128 0.0247 0.1104
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0535 0.214 0.2137
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0154 0.0368 0.1702
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Brugia malayi Protein kinase domain containing protein 0.0548 0.22 0.2196
Loa Loa (eye worm) hypothetical protein 0.011 0.0163 0.0158
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0007 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0706 0.1113
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0168 0.0435 0.2096
Echinococcus granulosus c src tyrosine kinase 0.0199 0.0578 0.0645
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0139 0.0299 0.1759
Echinococcus granulosus twitchin 0.0319 0.1136 0.1273
Brugia malayi Pleckstrin Homology Domain 0.0118 0.0201 0.0196
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0236 0.0747 0.0835
Brugia malayi Protein kinase domain containing protein 0.0381 0.1422 0.1418
Loa Loa (eye worm) hypothetical protein 0.022 0.0677 0.0672
Loa Loa (eye worm) TK protein kinase 0.0518 0.2061 0.2058
Echinococcus granulosus nervana 2 0.0243 0.0783 0.0876
Onchocerca volvulus 0.0149 0.0342 0.0376
Loa Loa (eye worm) hypothetical protein 0.0118 0.02 0.0195
Brugia malayi Protein kinase domain containing protein 0.0149 0.0342 0.0338
Brugia malayi diacylglycerol kinase 0.0105 0.0141 0.0137
Brugia malayi protein-tyrosine kinase 0.0293 0.1012 0.1008
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0436 0.1679 0.7631
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0145 0.0646
Onchocerca volvulus 0.022 0.0677 0.0748
Schistosoma mansoni hypothetical protein 0.016 0.0396 0.0622
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.1012 0.1372
Trichomonas vaginalis CMGC family protein kinase 0.0239 0.0762 0.3457
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0318 0.1129 0.1125
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0445 0.1721 0.1932
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0168 0.0435 0.2095
Loa Loa (eye worm) glutaminase 0.033 0.1186 0.1182
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0243 0.0783 0.106
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0557 0.224 0.3044
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0342 0.0338
Echinococcus multilocularis RNA directed DNA polymerase 0.0078 0.0015 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Schistosoma mansoni roundabout 0.011 0.0163 0.0251
Echinococcus multilocularis twitchin 0.0104 0.0136 0.0179
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0139 0.0299 0.1759
Trichomonas vaginalis CAMK family protein kinase 0.0234 0.0742 0.3362
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0163 0.0158
Schistosoma mansoni protein kinase 0.0162 0.0405 0.0635
Trypanosoma brucei cdc2-related kinase 1 0.0219 0.0672 0.304
Plasmodium falciparum serine/threonine protein kinase, putative 0.0436 0.1679 1
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0118 0.02 0.0266
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0093 0.0085 0.0391
Brugia malayi probable protein kinase 0.0288 0.099 0.0986
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0128 0.0247 0.0242
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0215 0.0651 0.1026
Loa Loa (eye worm) raf kinase 0.0946 0.405 0.4048
Entamoeba histolytica protein kinase domain containing protein 0.0436 0.1679 0.7631
Echinococcus multilocularis mitogen activated protein kinase 14 0.0299 0.1041 0.1411
Schistosoma mansoni protein kinase 0.0125 0.0233 0.0361
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0155 0.0372 0.05
Echinococcus multilocularis mitogen activated protein kinase 11 0.0299 0.1041 0.1411
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0005 0.5
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.01 0.0115 0.0499
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0219 0.0672 0.0668
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0436 0.1679 1
Echinococcus multilocularis hemicentin 1 0.011 0.0163 0.0216
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0501 0.2268
Plasmodium falciparum calcium-dependent protein kinase 4 0.0139 0.0299 0.1235
Loa Loa (eye worm) hypothetical protein 0.0234 0.0741 0.0737
Echinococcus granulosus epidermal growth factor receptor 0.0837 0.3545 0.3986
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0168 0.0435 0.0484
Schistosoma mansoni nephrin 0.0286 0.0983 0.1553
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0239 0.0762 0.369
Brugia malayi Protein kinase domain containing protein 0.0312 0.1102 0.1097
Giardia lamblia Aurora kinase 0.0436 0.1679 0.8049
Trypanosoma brucei SNF1-related protein kinases, putative 0.0128 0.0247 0.1104
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.1904 0.3016
Brugia malayi Protein kinase domain containing protein 0.0291 0.1005 0.1
Plasmodium falciparum serine/threonine protein kinase 0.01 0.0115 0.006
Echinococcus granulosus microtubule associated protein 2 0.143 0.6302 0.709
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0294 0.1018 0.1141
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Trypanosoma cruzi Protein kinase B 0.0307 0.1078 0.5226
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0168 0.0435 0.0586
Brugia malayi Stress-activated protein kinase jnk-1 0.0506 0.2003 0.1999
Echinococcus granulosus serine:threonine protein kinase N2 0.0127 0.0241 0.0266
Plasmodium vivax protein kinase, putative 0.0094 0.0089 0.0504
Entamoeba histolytica protein kinase, putative 0.0139 0.0299 0.1361
Echinococcus granulosus Glutaredoxin protein 5 0.0243 0.0783 0.0876
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0154 0.0368 0.0364
Loa Loa (eye worm) TK/FAK protein kinase 0.0575 0.2325 0.2321
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0388 0.1453 0.1449
Trichomonas vaginalis CAMK family protein kinase 0.0518 0.2058 0.9354
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0131 0.0261 0.0256
Schistosoma mansoni nck2/grb4 0.0125 0.0232 0.036
Schistosoma mansoni tyrosine kinase 0.0483 0.1896 0.3002
Echinococcus granulosus tyrosine protein kinase Lyn 0.0394 0.1482 0.1663
Echinococcus granulosus netrin receptor unc 5 0.0085 0.0045 0.0045
Giardia lamblia Kinase, CMGC CDK 0.0219 0.0672 0.2869
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0007 0.0004
Trypanosoma cruzi casein kinase, putative 0.0162 0.0405 0.1949
Schistosoma mansoni serine/threonine protein kinase 0.0518 0.2058 0.3261
Onchocerca volvulus 0.0149 0.0342 0.0376
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0243 0.0783 0.0876
Echinococcus granulosus casein kinase I alpha 0.0162 0.0405 0.045
Echinococcus multilocularis peroxidasin 0.0111 0.0166 0.0219
Loa Loa (eye worm) hypothetical protein 0.0104 0.0137 0.0132
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Trypanosoma cruzi casein kinase, putative 0.0162 0.0405 0.1949
Brugia malayi Protein kinase domain containing protein 0.0219 0.0672 0.0668
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0128 0.0246 0.0328
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.037 0.1374 0.1864
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0168 0.0435 0.043
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.015 0.0351 0.0347
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.011 0.0163 0.0158
Echinococcus granulosus tyrosine protein kinase Fyn 0.0343 0.1247 0.1399
Entamoeba histolytica protein kinase, putative 0.0535 0.214 0.9729
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0128 0.0247 0.1447
Schistosoma mansoni protein kinase 0.0155 0.0372 0.0583
Loa Loa (eye worm) hypothetical protein 0.0087 0.0056 0.0051
Brugia malayi glutaminase DH11.1 0.033 0.1186 0.1182
Echinococcus granulosus cGMP dependent protein kinase 1 0.015 0.0349 0.0387
Schistosoma mansoni septate junction protein 0.011 0.0163 0.0251
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0209 0.0996
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.0299 0.1349
Echinococcus multilocularis nervana 2 0.0243 0.0783 0.106
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0149 0.0342 0.1556
Loa Loa (eye worm) hypothetical protein 0.0273 0.0922 0.0917
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0168 0.0435 0.2095
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0226 0.0704 0.3403
Echinococcus multilocularis cyclin dependent kinase 0.0219 0.0672 0.0909
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0388 0.1453 0.1973
Trichomonas vaginalis AGC family protein kinase 0.0312 0.1102 0.5001
Echinococcus multilocularis PAK box P21 Rho binding 0.0112 0.0174 0.023
Entamoeba histolytica serine/threonine protein kinase, putative 0.0518 0.2058 0.9355
Brugia malayi Sex muscle abnormal protein 5 0.0125 0.0232 0.0227
Echinococcus multilocularis Rac GTPase activating protein 1 0.0105 0.0141 0.0186
Echinococcus multilocularis tyrosine protein kinase Srms 0.0293 0.1012 0.1372
Brugia malayi ephrin receptor 1 precursor 0.0134 0.0274 0.0269
Echinococcus granulosus serine:threonine protein kinase 0.021 0.0629 0.0703
Brugia malayi Protein kinase domain containing protein 0.0605 0.2464 0.246
Trichomonas vaginalis CMGC family protein kinase 0.0239 0.0762 0.3457
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0128 0.0247 0.033
Echinococcus multilocularis casein kinase I alpha 0.0162 0.0405 0.0545
Echinococcus multilocularis serine:threonine protein kinase N2 0.0292 0.1009 0.1367
Leishmania major protein kinase, putative 0.0168 0.0435 0.2095
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0239 0.0762 0.0853
Echinococcus multilocularis dual specificity 0.0154 0.0368 0.0495
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.01 0.0115 0.0513
Loa Loa (eye worm) hypothetical protein 0.0151 0.0355 0.035
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.052 0.0818
Echinococcus granulosus protein kinase 0.0168 0.0433 0.0482
Entamoeba histolytica protein kinase domain containing protein 0.0239 0.0762 0.3466
Schistosoma mansoni protein kinase 0.0168 0.0433 0.068
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0125 0.0233 0.0311
Echinococcus multilocularis epidermal growth factor receptor 0.0563 0.2271 0.3086
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0376 0.1401 0.1397
Schistosoma mansoni protein kinase 0.0431 0.1655 0.2621
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.012 0.0209 0.0996
Trichomonas vaginalis esterase, putative 0.0076 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0105 0.0141 0.0137
Echinococcus granulosus serine threonine protein kinase nrc 0.0294 0.1018 0.1141
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0179 0.0486 0.0481
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.0355 0.035
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0007 0.0004
Plasmodium falciparum calcium-dependent protein kinase 2 0.0139 0.0299 0.1235
Echinococcus multilocularis hemicentin 1 0.011 0.0163 0.0216
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.1009 0.1594
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0168 0.0435 0.2094
Entamoeba histolytica protein kinase, putative 0.0226 0.0704 0.3198
Trichomonas vaginalis AGC family protein kinase 0.0325 0.1161 0.5273
Loa Loa (eye worm) TK protein kinase 0.0371 0.1376 0.1372
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0312 0.1102 0.1097
Brugia malayi Protein kinase domain containing protein 0.0079 0.0018 0.0013
Echinococcus granulosus tyrosine protein kinase Src64B 0.0343 0.1247 0.1399
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.012 0.0209 0.023
Loa Loa (eye worm) hypothetical protein 0.0105 0.0141 0.0137
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0154 0.0368 0.1656
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0083 0.0039 0.0166
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0368 0.1664
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0246 0.0241
Trichomonas vaginalis AGC family protein kinase 0.0548 0.22 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0239 0.0762 0.0758
Loa Loa (eye worm) hypothetical protein 0.0271 0.0913 0.0909
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0371 0.1378 0.1869
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0146 0.0331 0.0326
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Brugia malayi RhoGAP domain containing protein 0.0105 0.0141 0.0137
Giardia lamblia Kinase, STE STE20 0.0155 0.0372 0.1325
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0155 0.0372 0.0413
Onchocerca volvulus 0.0108 0.0153 0.0165
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0342 0.0338
Echinococcus granulosus titin 0.0122 0.0219 0.0241
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.012 0.0209 0.0205
Leishmania major casein kinase II, putative 0.0183 0.0501 0.2417
Loa Loa (eye worm) TK protein kinase 0.0309 0.1087 0.1083
Brugia malayi Hr1 repeat family protein 0.0419 0.1598 0.1594
Entamoeba histolytica cell division protein kinase 2, putative 0.0219 0.0672 0.3055
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.011 0.0163 0.0216
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.01 0.0115 0.0534
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.015 0.0349 0.1609
Loa Loa (eye worm) hypothetical protein 0.0139 0.0299 0.0295
Trichomonas vaginalis set domain proteins, putative 0.0286 0.0982 0.4454
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0168 0.0435 0.2095
Giardia lamblia Kinase, CDC7 0.0106 0.0145 0.0156
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0216 0.0658 0.0735
Brugia malayi Ras association domain family 1 isoform A 0.0105 0.0141 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0254 0.0831 0.3768
Schistosoma mansoni vav2 0.0192 0.0546 0.0859
Schistosoma mansoni neuroglian 0.0128 0.0246 0.0382
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0271 0.0912 0.0907
Echinococcus granulosus calcium dependent protein kinase 0.0089 0.0064 0.0067
Echinococcus granulosus serine:threonine protein kinase 0.021 0.0629 0.0703
Schistosoma mansoni protein kinase 0.0183 0.0501 0.0788
Schistosoma mansoni tyrosine kinase 0.0283 0.0968 0.1529
Entamoeba histolytica casein kinase 1, putative 0.0162 0.0405 0.1841
Entamoeba histolytica protein kinase, putative 0.0436 0.1679 0.7631
Schistosoma mansoni serine/threonine protein kinase 0.0419 0.1598 0.253
Entamoeba histolytica protein kinase domain containing protein 0.0226 0.0704 0.3198
Echinococcus multilocularis calcium dependent protein kinase 0.0089 0.0064 0.0081
Schistosoma mansoni cell adhesion molecule 0.0128 0.0246 0.0382
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0343 0.1247 0.1692
Brugia malayi hypothetical protein 0.0233 0.0733 0.0729
Loa Loa (eye worm) hypothetical protein 0.0215 0.0654 0.0649
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0139 0.0299 0.0332
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0299 0.1041 0.472
Leishmania major protein kinase, putative 0.0139 0.0299 0.1434
Brugia malayi hypothetical protein 0.0078 0.0012 0.0007
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0506 0.2003 0.1999
Leishmania major protein kinase, putative 0.0125 0.0233 0.1109
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0501 0.2268
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0179 0.0486 0.0764
Schistosoma mansoni serine/threonine protein kinase 0.0762 0.3192 0.5061
Loa Loa (eye worm) AUR protein kinase 0.0436 0.1679 0.1675
Brugia malayi Cam kinase protein 1 0.0139 0.0299 0.0295
Schistosoma mansoni diacylglycerol kinase theta 0.0105 0.0141 0.0217
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0093 0.0085 0.008
Entamoeba histolytica protein kinase, putative 0.0239 0.0762 0.3466
Loa Loa (eye worm) hypothetical protein 0.0326 0.1166 0.1162
Schistosoma mansoni growth factor receptor-bound protein 0.0125 0.0232 0.036
Echinococcus granulosus tyrosine protein kinase shark 0.0357 0.1313 0.1472
Echinococcus multilocularis Diacylglycerol kinase theta 0.0105 0.0141 0.0186
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.015 0.0351 0.1687
Echinococcus multilocularis 0.0168 0.0433 0.0583
Trichomonas vaginalis CMGC family protein kinase 0.0219 0.0672 0.3046
Brugia malayi Furin-like cysteine rich region family protein 0.0837 0.3545 0.3542
Trypanosoma brucei casein kinase I, isoform 2 0.0162 0.0405 0.1823
Brugia malayi Fes/CIP4 homology domain containing protein 0.0125 0.0232 0.0227
Brugia malayi Immunoglobulin I-set domain containing protein 0.0233 0.0733 0.0729
Echinococcus granulosus casein kinase I alpha 0.0162 0.0405 0.045
Echinococcus granulosus calcium activated potassium channel 0.0211 0.0631 0.0705
Entamoeba histolytica PH domain containing protein kinase, putative 0.0307 0.1078 0.49
Schistosoma mansoni protein kinase 0.0388 0.1453 0.23
Loa Loa (eye worm) TK/KIN16 protein kinase 0.2226 1 1
Brugia malayi hypothetical protein 0.012 0.0209 0.0205
Entamoeba histolytica PH domain containing protein kinase, putative 0.0307 0.1078 0.49
Trichomonas vaginalis STE family protein kinase 0.0152 0.036 0.1624
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0128 0.0246 0.0328
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0093 0.0085 0.008
Echinococcus granulosus cyclin dependent kinase 1 0.0219 0.0672 0.0751
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0131 0.026 0.0347
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0343 0.1247 0.1692
Schistosoma mansoni rac gtpase activating protein 0.0105 0.0141 0.0217
Loa Loa (eye worm) hypothetical protein 0.0111 0.0166 0.0161
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0445 0.1721 0.2337
Brugia malayi SRC-1 0.0343 0.1247 0.1243
Echinococcus multilocularis Glutaredoxin protein 5 0.0243 0.0783 0.106
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0457 0.1778 0.2415
Echinococcus granulosus RNA directed DNA polymerase 0.0078 0.0015 0.0011
Echinococcus multilocularis protein kinase c epsilon type 0.04 0.151 0.205
Brugia malayi diacylglycerol kinase 0.0105 0.0141 0.0137
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0342 0.0338
Entamoeba histolytica protein kinase, putative 0.0125 0.0233 0.1061
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0478 0.1873 0.2544
Echinococcus multilocularis protein kinase c iota type 0.056 0.2257 0.3067
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0318 0.1129 0.1266
Echinococcus multilocularis activin receptor type 0.0125 0.0233 0.031
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.012 0.0209 0.0278
Echinococcus granulosus neuroglian 0.0128 0.0246 0.0271
Brugia malayi Protein kinase domain containing protein 0.184 0.8204 0.8204
Schistosoma mansoni ephrin receptor 0.02 0.0583 0.0919
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0007 0.0004
Echinococcus granulosus serine:threonine protein kinase 3 0.0491 0.1935 0.2173
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0762 0.3192 0.3588
Giardia lamblia Kinase, CMGC GSK 0.0239 0.0762 0.3334
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0247 0.0385
Loa Loa (eye worm) hypothetical protein 0.0105 0.0141 0.0137
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0219 0.0672 0.0751
Echinococcus multilocularis dual specificity 0.0226 0.0704 0.0952
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0239 0.0762 0.1203
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0292 0.1009 0.113
Onchocerca volvulus 0.0273 0.0922 0.1021
Schistosoma mansoni microtubule-associated protein tau 0.143 0.6302 1
Brugia malayi Protein kinase domain containing protein 0.0149 0.0342 0.0338
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0318 0.1129 0.1125
Brugia malayi Doublecortin family protein 0.0166 0.0422 0.0418
Entamoeba histolytica protein kinase, putative 0.0154 0.0368 0.1675
Loa Loa (eye worm) TK protein kinase 0.0218 0.0667 0.0663
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.0355 0.035
Giardia lamblia Kinase, CMGC DYRK 0.0154 0.0368 0.1306
Brugia malayi Casein kinase II, alpha chain 0.0183 0.0501 0.0496
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0168 0.0435 0.2014
Schistosoma mansoni serine/threonine protein kinase 0.04 0.151 0.239
Brugia malayi Protein kinase domain containing protein 0.0287 0.0985 0.0981
Toxoplasma gondii AGC kinase 0.0168 0.0435 0.2014
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0115 0.0174
Schistosoma mansoni growth factor receptor-bound protein 0.0127 0.0241 0.0374
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0168 0.0435 0.196
Giardia lamblia Kinase, NEK 0.0254 0.0831 0.3685
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0007 0.0002
Loa Loa (eye worm) thyroid receptor interactor 0.0125 0.0232 0.0227
Brugia malayi Variant SH3 domain containing protein 0.0089 0.0068 0.0063
Echinococcus multilocularis N chimaerin 0.0179 0.0486 0.0655
Echinococcus granulosus raf serine:threonine protein kinase 0.1021 0.4396 0.4944
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Echinococcus granulosus fibroblast growth factor receptor 4 0.0465 0.1812 0.2034
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0007 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0518 0.2058 0.9354
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0219 0.0672 0.325
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0351 0.055
Schistosoma mansoni protein kinase 0.0465 0.1813 0.2871
Toxoplasma gondii histone kinase SNF1, putative 0.0128 0.0247 0.1134
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0233 0.0733 0.0729
Schistosoma mansoni protein kinase 0.0155 0.0372 0.0583
Echinococcus multilocularis titin 0.0122 0.0219 0.0291
Echinococcus multilocularis cGMP dependent protein kinase 1 0.015 0.0349 0.0468
Loa Loa (eye worm) hypothetical protein 0.0077 0.001 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0085 0.0045 0.004
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0076 0.0007 0.0002
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0128 0.0246 0.0271
Echinococcus granulosus NCK adaptor protein 0.0125 0.0232 0.0255
Schistosoma mansoni tyrosine kinase 0.0343 0.1247 0.1973
Echinococcus multilocularis mitogen activated protein kinase 3 0.015 0.0351 0.0472
Brugia malayi putative serine/threonine kinase SADA gamma 0.0128 0.0247 0.0242
Echinococcus granulosus mitogen activated protein kinase 0.015 0.0351 0.039
Loa Loa (eye worm) AGC/AKT protein kinase 0.0548 0.22 0.2196
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0351 0.1586
Plasmodium falciparum protein kinase 5 0.0219 0.0672 0.3603
Echinococcus multilocularis casein kinase I delta 0.0162 0.0405 0.0545
Echinococcus granulosus casein kinase I alpha 0.0162 0.0405 0.045
Echinococcus multilocularis ephrin type A receptor 4 A 0.02 0.0583 0.0788
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0083 0.0039 0.0166
Echinococcus granulosus rho-associated protein kinase 1 0.0626 0.256 0.2877
Echinococcus multilocularis roundabout 2 0.0343 0.1245 0.1689
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0343 0.1247 0.1692
Schistosoma mansoni septate junction protein 0.011 0.0163 0.0251
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0431 0.1655 0.2248
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0128 0.0247 0.118
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0128 0.0247 0.118
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0093 0.0085 0.008
Schistosoma mansoni vesicular amine transporter 0.0215 0.0651 0.1026
Brugia malayi hypothetical protein 0.0236 0.0747 0.0742
Brugia malayi Protein kinase domain containing protein 0.0647 0.2659 0.2655
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0168 0.0435 0.0586
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Echinococcus granulosus tyrosine protein kinase Src42A 0.022 0.0675 0.0755
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0704 0.111
Brugia malayi Protein kinase domain containing protein 0.0226 0.0704 0.0699
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0007 0.0002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.015 0.0351 0.1687
Loa Loa (eye worm) AGC/NDR protein kinase 0.0292 0.1009 0.1004
Brugia malayi Temporarily assigned gene name protein 59 0.0254 0.0832 0.0828
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Brugia malayi SH2 domain containing protein 0.0149 0.0342 0.0338
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0506 0.2003 0.2721
Brugia malayi Prion-like- 0.011 0.0163 0.0158
Echinococcus multilocularis dual specificity 0.0154 0.0368 0.0495
Loa Loa (eye worm) hypothetical protein 0.0215 0.0651 0.0647
Brugia malayi Variant SH3 domain containing protein 0.0125 0.0232 0.0227
Schistosoma mansoni tyrosine kinase 0.0199 0.0578 0.0909
Brugia malayi Protein kinase domain containing protein 0.0605 0.2464 0.246
Entamoeba histolytica protein kinase, putative 0.0436 0.1679 0.7631
Entamoeba histolytica protein kinase, putative 0.0125 0.0233 0.1061
Echinococcus multilocularis tyrosine kinase 0.0149 0.0342 0.0459
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0292 0.1009 0.113
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0299 0.1041 0.5047
Brugia malayi Protein kinase domain containing protein 0.0388 0.1453 0.1449
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0521 0.2075 0.2071
Trichomonas vaginalis CAMK family protein kinase 0.0518 0.2058 0.9354
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0747 0.1178
Schistosoma mansoni hypothetical protein 0.016 0.0396 0.0622
Echinococcus granulosus tyrosine protein kinase Fyn 0.0343 0.1247 0.1399
Schistosoma mansoni serine/threonine-protein kinase 0.0307 0.1078 0.1704
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0039 0.0166
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0125 0.0233 0.1037
Trichomonas vaginalis AGC family protein kinase 0.0436 0.1679 0.7628
Schistosoma mansoni tyrosine kinase 0.0563 0.2271 0.3599
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0331 0.0517
Brugia malayi phosphoinositide-dependent protein kinase I 0.0146 0.0331 0.0326
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0521 0.2075 0.2071
Onchocerca volvulus 0.188 0.8393 0.9337
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.0896 0.1415
Brugia malayi Variant SH3 domain containing protein 0.0179 0.0486 0.0481
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0125 0.0233 0.0257
Brugia malayi p70 ribosomal S6 kinase beta 0.0535 0.214 0.2137
Brugia malayi RhoGAP domain containing protein 0.0179 0.0486 0.0481
Giardia lamblia Kinase, CMGC GSK 0.0239 0.0762 0.3334
Loa Loa (eye worm) TK/ABL protein kinase 0.0557 0.224 0.2236
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0207 0.0613 0.0609
Echinococcus multilocularis Immunoglobulin 0.0215 0.0651 0.088
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0294 0.1018 0.6053
Brugia malayi MH2 domain containing protein 0.0247 0.0802 0.0798
Loa Loa (eye worm) hypothetical protein 0.011 0.0163 0.0158
Brugia malayi Tyrosine-protein kinase abl-1 0.0355 0.1303 0.1299
Trichomonas vaginalis CK1 family protein kinase 0.0162 0.0405 0.183
Loa Loa (eye worm) glutaminase 2 0.033 0.1186 0.1182
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0381 0.1422 0.1418
Schistosoma mansoni tyrosine kinase 0.0489 0.1925 0.3049
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0162 0.0405 0.04
Echinococcus granulosus neuroglian 0.0269 0.0901 0.1009
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.01 0.0115 0.0534
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0307 0.1078 0.5226
Brugia malayi Variant SH3 domain containing protein 0.0125 0.0232 0.0227
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0154 0.0368 0.177
Trichomonas vaginalis AGC family protein kinase 0.0548 0.22 1
Plasmodium falciparum casein kinase 1 0.0162 0.0405 0.1906
Echinococcus granulosus tyrosine kinase 0.0293 0.1012 0.1134
Loa Loa (eye worm) MH2 domain-containing protein 0.0247 0.0802 0.0798
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0343 0.1247 0.1399
Entamoeba histolytica hypothetical protein 0.0372 0.1379 0.6268
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0105 0.0141 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0247 0.1112
Echinococcus granulosus expressed protein 0.01 0.0115 0.0123
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0125 0.0233 0.0257
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0254 0.0831 0.3868
Brugia malayi SH2 domain containing protein 0.0445 0.1721 0.1717
Echinococcus multilocularis expressed conserved protein 0.015 0.0349 0.0468
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0665 0.2741 0.3726
Trichomonas vaginalis CAMK family protein kinase 0.0518 0.2058 0.9354
Entamoeba histolytica protein kinase, putative 0.0125 0.0233 0.1061
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0125 0.0233 0.1066
Loa Loa (eye worm) hypothetical protein 0.0103 0.0132 0.0127
Entamoeba histolytica serine/threonine protein kinase, putative 0.0128 0.0247 0.1123
Plasmodium vivax casein kinase 1, putative 0.0162 0.0405 0.239
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0154 0.0368 0.177
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0155 0.0372 0.05
Entamoeba histolytica protein kinase , putative 0.0436 0.1679 0.7631
Schistosoma mansoni serine/threonine protein kinase 0.0139 0.0299 0.0468
Leishmania major protein kinase, putative 0.0436 0.1679 0.8153
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0163 0.0158
Echinococcus multilocularis tyrosine protein kinase HCK 0.0218 0.0667 0.0902
Entamoeba histolytica protein kinase, putative 0.0155 0.0372 0.1691
Loa Loa (eye worm) hypothetical protein 0.0371 0.1375 0.1371
Onchocerca volvulus 0.0286 0.0982 0.1087
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0168 0.0435 0.2094
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0631 0.0995

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.6573 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 1.8526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 1.9953 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 6.3096 uM PUBCHEM_BIOASSAY: qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485366, AID485386, AID504448, AID504454, AID504459] ChEMBL. No reference
Potency (functional) 6.3096 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.081 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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