Detailed information for compound 145776

Basic information

Technical information
  • TDR Targets ID: 145776
  • Name: 4-[[(2S)-1-(2,2-dichlorocyclopropyl)oxy-1-oxo -3-phenylpropan-2-yl]amino]-4-oxobutanoic aci d
  • MW: 374.216 | Formula: C16H17Cl2NO5
  • H donors: 2 H acceptors: 4 LogP: 2.24 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N[C@H](C(=O)OC1CC1(Cl)Cl)Cc1ccccc1)CCC(=O)O
  • InChi: 1S/C16H17Cl2NO5/c17-16(18)9-12(16)24-15(23)11(8-10-4-2-1-3-5-10)19-13(20)6-7-14(21)22/h1-5,11-12H,6-9H2,(H,19,20)(H,21,22)/t11-,12?/m0/s1
  • InChiKey: CIRFDBFEOGFGRQ-PXYINDEMSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[[(1S)-1-benzyl-2-(2,2-dichlorocyclopropoxy)-2-oxo-ethyl]amino]-4-oxo-butanoic acid
  • 4-[[(1S)-1-benzyl-2-(2,2-dichlorocyclopropoxy)-2-oxoethyl]amino]-4-oxobutanoic acid
  • 4-[[(2S)-1-(2,2-dichlorocyclopropyl)oxy-1-oxo-3-phenyl-propan-2-yl]amino]-4-oxo-butanoic acid
  • 4-[[(1S)-1-benzyl-2-(2,2-dichlorocyclopropoxy)-2-keto-ethyl]amino]-4-keto-butyric acid
  • 4-[[(1S)-2-(2,2-dichlorocyclopropoxy)-2-oxo-1-(phenylmethyl)ethyl]amino]-4-oxo-butanoic acid
  • 4-[[(1S)-2-(2,2-dichlorocyclopropoxy)-2-oxo-1-(phenylmethyl)ethyl]amino]-4-oxobutanoic acid
  • 4-[[(1S)-1-(benzyl)-2-(2,2-dichlorocyclopropoxy)-2-keto-ethyl]amino]-4-keto-butyric acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii hypothetical protein 0.0015 0.0098 0.0835
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.2468 0.4065
Loa Loa (eye worm) AUR protein kinase 0.0114 0.1169 0.4507
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0082 0.0134
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0014 0.009 0.0715
Schistosoma mansoni thyroid hormone receptor 0.001 0.0049 0.0081
Trypanosoma cruzi aldo/keto reductase, putative 0.0017 0.0129 0.1102
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0125 0.1287 0.1331
Echinococcus multilocularis Glutaredoxin protein 5 0.0012 0.0072 0.0119
Loa Loa (eye worm) hypothetical protein 0.0069 0.0677 0.2611
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Echinococcus granulosus serine/threonine protein kinase 0.0014 0.009 0.0149
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0006 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.0938 1 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0012 0.0075 0.0643
Mycobacterium ulcerans aldehyde dehydrogenase 0.01 0.1009 0.1009
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0031 0.0273 0.1448
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0008 0.0022 0.0022
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Echinococcus multilocularis sodium and chloride dependent glycine 0.0014 0.0091 0.015
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0032 0.0053
Echinococcus multilocularis geminin 0.0169 0.1752 0.2885
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0032 0.0053
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0049 0.0081
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0189
Loa Loa (eye worm) hypothetical protein 0.0014 0.0091 0.035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0075 0.0745 0.2359
Entamoeba histolytica protein kinase, putative 0.002 0.0157 0.0833
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0119 0.1015
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.005 0.0476 0.1836
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0119 0.0629
Loa Loa (eye worm) TAR-binding protein 0.0032 0.0286 0.1102
Echinococcus multilocularis tar DNA binding protein 0.0032 0.0286 0.047
Loa Loa (eye worm) hypothetical protein 0.0082 0.0822 0.3172
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0015 0.0098 0.0161
Treponema pallidum fructose-bisphosphate aldolase 0.0073 0.0725 0.8817
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0017 0.0129 0.1102
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0022 0.0085
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0036 0.0324 0.0324
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0006 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0006 0.0006 0.0009
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.0032 0.0053
Trypanosoma brucei phosphonopyruvate decarboxylase-like protein, putative 0.0013 0.0075 0.0646
Trichomonas vaginalis AGC family protein kinase 0.002 0.0157 0.0498
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0008 0.0032 0.0053
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Echinococcus multilocularis serine:threonine protein kinase N2 0.0008 0.0026 0.0043
Entamoeba histolytica hypothetical protein 0.0015 0.0102 0.0543
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0119 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0129 0.0212
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0072 0.0276
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0119 0.1213 0.1998
Mycobacterium tuberculosis Acetolactate synthase (large subunit) IlvB1 (acetohydroxy-acid synthase) 0.0017 0.0119 0.0123
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0531 0.0875
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0114 0.1169 0.1924
Loa Loa (eye worm) hypothetical protein 0.0032 0.0288 0.1113
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0014 0.0091 0.015
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0081 0.0806 0.2556
Mycobacterium ulcerans hypothetical protein 0.0039 0.0357 0.0357
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0012 0.0075 0.0643
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Brugia malayi larval opioid receptor 0.0008 0.0032 0.0123
Giardia lamblia Pyruvate-flavodoxin oxidoreductase 0.0006 0.0002 0.0009
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0008 0.0022 0.0023
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.1109 0.1109
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0081 0.0806 0.1328
Loa Loa (eye worm) hypothetical protein 0.0018 0.0132 0.0511
Schistosoma mansoni protein farnesyltransferase subunit beta 0.005 0.0476 0.0784
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0453 0.0469
Loa Loa (eye worm) ILVBL protein 0.0023 0.0193 0.0743
Loa Loa (eye worm) oxidoreductase 0.0017 0.0129 0.0497
Echinococcus granulosus dnaJ subfamily B 0.0019 0.0146 0.0241
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0015 0.0098 0.0161
Echinococcus multilocularis serotonin receptor 0.004 0.0374 0.0616
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0119 0.1015
Entamoeba histolytica protein kinase, putative 0.0114 0.1169 0.6196
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0056 0.0544 0.0896
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0014
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0014 0.0086 0.0738
Loa Loa (eye worm) hypothetical protein 0.0019 0.0146 0.0564
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0012 0.0073 0.0121
Treponema pallidum NADH oxidase 0.0017 0.0119 0.1442
Loa Loa (eye worm) hypothetical protein 0.0008 0.0026 0.0101
Echinococcus granulosus neuropeptide receptor A26 0.0008 0.0032 0.0053
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0247 0.2593 1
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0006 0 0.0001
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.0907 0.9668 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0006 0.0009 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0008 0.0022 0.0023
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0049 0.0189
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Giardia lamblia Rab geranylgeranyltransferase 0.0021 0.0169 0.0898
Echinococcus multilocularis nervana 2 0.0012 0.0072 0.0119
Echinococcus multilocularis glutathione S transferase 0.0092 0.0925 0.1523
Leishmania major putative pyruvate/indole-pyruvate carboxylase, putative 0.0022 0.0179 0.1531
Echinococcus granulosus hyperpolarization activated cyclic 0.0006 0 0.0001
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0008 0.0032 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0049 0.0189
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.1109 0.1147
Loa Loa (eye worm) hypothetical protein 0.0013 0.0085 0.0326
Schistosoma mansoni biogenic amine receptor 0.0008 0.0032 0.0053
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0056 0.0544 0.4452
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0056 0.0541 0.1714
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0189
Toxoplasma gondii aldehyde dehydrogenase 0.01 0.1009 0.8632
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0008 0.0026 0.0043
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0053
Brugia malayi G-protein coupled receptor 0.0008 0.0032 0.0123
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0181 0.1886 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0017 0.012 0.1029
Entamoeba histolytica hypothetical protein 0.0115 0.1172 0.6215
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0008 0.0032 0.0123
Giardia lamblia DNA topoisomerase II 0.0027 0.0233 0.1236
Trichomonas vaginalis pyruvate-flavodoxin oxidoreductase, putative 0.0006 0.0002 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0049 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0049 0.0189
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0541 0.4628
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0092 0.0927 0.1526
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0073 0.0725 0.2298
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0014 0.009 0.0149
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0119 0.1015
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0021 0.0169 0.0898
Brugia malayi Protein kinase domain containing protein 0.0008 0.0026 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0049 0.0189
Loa Loa (eye worm) TYRA-2 protein 0.0008 0.0032 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0374 0.1443
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.005 0.0476 0.1508
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0098 0.0835
Echinococcus multilocularis protein kinase c epsilon type 0.0008 0.0026 0.0043
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0081 0.0806 0.1328
Loa Loa (eye worm) hypothetical protein 0.0014 0.0091 0.035
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0055 0.0531 0.2047
Loa Loa (eye worm) voltage-dependent calcium channel 0.0032 0.0288 0.1113
Schistosoma mansoni hypothetical protein 0.002 0.0152 0.025
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0008 0.0032 0.0101
Echinococcus granulosus glutathione S transferase Mu 1 0.0027 0.0229 0.0378
Toxoplasma gondii hypothetical protein 0.0006 0.0009 0.0081
Loa Loa (eye worm) hypothetical protein 0.0105 0.107 0.4125
Echinococcus multilocularis glutathione S transferase 0.0027 0.0229 0.0378
Echinococcus granulosus voltage dependent calcium channel 0.0032 0.0288 0.0475
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0119 0.0923
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0081 0.0806 0.311
Echinococcus granulosus tar DNA binding protein 0.0032 0.0286 0.047
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0053 0.0515 0.1984
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Onchocerca volvulus 0.0008 0.0032 0.0101
Echinococcus granulosus aurora kinase A 0.0114 0.1169 0.1924
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0073 0.0725 0.2298
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0015 0.0098 0.0835
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0049 0.0081
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0008 0.0022 0.0023
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Trypanosoma cruzi PAB1-binding protein , putative 0.0013 0.0085 0.0723
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.002 0.0157 0.0606
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0014 0.009 0.0772
Loa Loa (eye worm) hypothetical protein 0.002 0.0152 0.0586
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0014 0.0091 0.015
Echinococcus granulosus sex peptide receptor 0.0008 0.0032 0.0053
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0008 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0013 0.0076 0.0294
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0049 0.0189
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0015 0.0098 0.0835
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0119 0.1015
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0119 0.0195
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0049 0.0189
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0119 0.0119
Entamoeba histolytica aldose reductase, putative 0.0017 0.0129 0.0683
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0189
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0018 0.0132 0.0511
Brugia malayi neuropeptide F receptor 0.0008 0.0032 0.0123
Toxoplasma gondii hypothetical protein 0.0014 0.0091 0.0777
Schistosoma mansoni biogenic amine receptor 0.0008 0.0032 0.0053
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0018 0.0132 0.042
Trypanosoma brucei calpain-like protein, putative 0.0012 0.0075 0.0643
Loa Loa (eye worm) thiamine pyrophosphate enzyme 0.0022 0.0179 0.0691
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0008 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Mycobacterium leprae Conserved hypothetical protein 0.0012 0.0074 0.0074
Trypanosoma brucei aurora B kinase 0.0114 0.1169 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0054 0.0526 0.0865
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.1169 0.1924
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0021 0.0163 0.0516
Loa Loa (eye worm) RNA binding protein 0.0032 0.0286 0.1102
Brugia malayi hypothetical protein 0.002 0.0152 0.0586
Plasmodium falciparum plasmepsin VI 0.0018 0.0132 0.1078
Trichomonas vaginalis pyruvate-flavodoxin oxidoreductase, putative 0.0006 0.0002 0.0005
Onchocerca volvulus 0.0017 0.0129 0.0408
Echinococcus granulosus lamin dm0 0.0008 0.0024 0.004
Entamoeba histolytica DNA topoisomerase II, putative 0.0028 0.0247 0.1308
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0053 0.0515 0.1984
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0008 0.0032 0.0053
Brugia malayi glutathione transferase 0.0027 0.0229 0.0885
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0008 0.0022 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0053
Schistosoma mansoni aldehyde dehydrogenase 0.01 0.1009 0.1661
Schistosoma mansoni hypothetical protein 0.0169 0.1752 0.2885
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0008 0.0022 0.0022
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0115 0.1172 0.193
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0008 0.0022 0.0188
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0049 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0049 0.0189
Echinococcus granulosus eukaryotic translation elongation factor 1 0.0006 0.0007 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0032 0.0286 0.047
Entamoeba histolytica protein kinase, putative 0.0114 0.1169 0.6196
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0181 0.1886 0.1886
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0092 0.0927 0.1526
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0119 0.1015
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0119 0.0457
Trypanosoma brucei trypanothione reductase 0.0048 0.0453 0.3877
Echinococcus granulosus RUN 0.002 0.0152 0.025
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0029 0.0248 0.1994
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0012 0.0075 0.0643
Plasmodium vivax SET domain protein, putative 0.0054 0.0526 0.4297
Mycobacterium leprae Conserved hypothetical protein 0.0008 0.0022 0.0022
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0049 0.0081
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Brugia malayi glutathione reductase 0.0048 0.0453 0.1747
Echinococcus multilocularis allatostatin A receptor 0.0008 0.0032 0.0053
Giardia lamblia Aldose reductase 0.0017 0.0129 0.0683
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0008 0.0022 0.0023
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.01 0.1009 0.8632
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0053
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0119 0.1015
Echinococcus granulosus protein farnesyltransferase subunit beta 0.005 0.0476 0.0784
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0049 0.0189
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0026 0.0083
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0049 0.0081
Echinococcus granulosus aldehyde reductase 0.0012 0.0074 0.0123
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0008 0.0026 0.0043
Echinococcus granulosus allatostatin A receptor 0.0008 0.0032 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0053
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0098 0.0835
Mycobacterium tuberculosis Conserved hypothetical protein 0.0031 0.0273 0.0283
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0919 0.1513
Echinococcus granulosus protein kinase C gamma type 0.0008 0.0026 0.0043
Schistosoma mansoni hypothetical protein 0.0048 0.0457 0.0752
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Brugia malayi Serotonin receptor 0.0008 0.0032 0.0123
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0073 0.0725 0.2298
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0049 0.0081
Mycobacterium ulcerans acetolactate synthase 0.0022 0.0179 0.0179
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0152 0.025
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0174 0.1804 0.6959
Echinococcus granulosus glutathione S transferase 0.0021 0.0163 0.0269
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0114 0.1169 0.6196
Echinococcus multilocularis RUN 0.002 0.0152 0.025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0053
Trichomonas vaginalis aldo/keto reductase, putative 0.0017 0.0129 0.0408
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Brugia malayi SET domain containing protein 0.0071 0.0698 0.2694
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0021 0.0169 0.0279
Giardia lamblia Fructose-bisphosphate aldolase 0.0073 0.0725 0.3844
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0056 0.0544 0.1724
Schistosoma mansoni protein kinase 0.0114 0.1169 0.1924
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0032 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0008 0.0022 0.0023
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0032 0.0123
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0129 0.0212
Trypanosoma cruzi Wee1-like protein kinase, putative 0.0014 0.0086 0.0738
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0056 0.0544 0.2099
Echinococcus granulosus glutathione S transferase 0.0006 0.0007 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0026 0.0043
Trypanosoma brucei hypothetical protein 0.0012 0.0075 0.0643
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0032 0.0288 0.2469
Brugia malayi Latrophilin receptor protein 2 0.0055 0.0531 0.2047
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0032 0.0053
Loa Loa (eye worm) cytochrome P450 0.0008 0.0022 0.0085
Schistosoma mansoni tar DNA-binding protein 0.0032 0.0286 0.047
Echinococcus granulosus Glutaredoxin protein 5 0.0012 0.0072 0.0119
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0012 0.0072 0.0119
Trypanosoma cruzi lanosterol synthase, putative 0.0021 0.0169 0.145
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0152 0.1246
Schistosoma mansoni hypothetical protein 0.0055 0.0531 0.0874
Loa Loa (eye worm) hypothetical protein 0.0174 0.1804 0.6959
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0052 0.0504 0.083
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0008 0.0032 0.0053
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0006 0.0009 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0032 0.0053
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0049 0.0081
Echinococcus granulosus 7tm_1 domain containing protein 0.0008 0.0032 0.0053
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0006 0.0009 0.0014
Echinococcus granulosus G protein coupled receptor 139 0.0008 0.0032 0.0053
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0082 0.0822 0.3172
Echinococcus granulosus calcium activated potassium channel 0.0006 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0055 0.0531 0.2047
Onchocerca volvulus 0.0008 0.0032 0.0101
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0018 0.0132 0.0218
Brugia malayi p70 ribosomal S6 kinase beta 0.002 0.0157 0.0606
Brugia malayi latrophilin 2 splice variant baaae 0.0119 0.1215 0.4686
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus multilocularis glutathione S-transferase 0.0027 0.0229 0.0378
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0022 0.0188
Echinococcus granulosus g-protein coupled receptor 0.0008 0.0032 0.0053
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0017 0.012 0.0198
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0012 0.0072 0.0119
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0017 0.0129 0.1102
Echinococcus granulosus voltage gated potassium channel 0.0006 0.0009 0.0014
Plasmodium vivax amine transporter, putative 0.0014 0.0091 0.0693
Echinococcus granulosus lamin 0.0008 0.0024 0.004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0119 1
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0032 0.0053
Brugia malayi ecdysteroid receptor 0.001 0.0049 0.0189
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0049 0.0081
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0017 0.012 0.0198
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0026 0.0083
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.1239 0.1281
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0032 0.0123
Echinococcus multilocularis orexin receptor type 2 0.0008 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.0021 0.0163 0.063
Schistosoma mansoni rab6-interacting 0.002 0.0152 0.025
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0026 0.0043
Echinococcus multilocularis protein kinase c iota type 0.0008 0.0026 0.0043
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0049 0.0081
Mycobacterium ulcerans 2-oxoglutarate ferredoxin oxidoreductase subunit beta 0.0006 0.0002 0.0002
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0006 0 0.0001
Schistosoma mansoni neuropeptide f receptor 76f 0.0008 0.0032 0.0053
Brugia malayi serine/threonine protein kinase 6 0.0114 0.1169 0.4507
Loa Loa (eye worm) hypothetical protein 0.0054 0.0526 0.2027
Trypanosoma brucei C-8 sterol isomerase, putative 0.0107 0.1092 0.934
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0008 0.0032 0.0123
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0119 0.0195
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Schistosoma mansoni hypothetical protein 0.0008 0.0022 0.0036
Echinococcus granulosus dro:myosuppressin receptor 0.0008 0.0032 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0123 0.1261 0.2077
Echinococcus granulosus sodium and chloride dependent glycine 0.0014 0.0091 0.015
Schistosoma mansoni alpha-1 adrenergic receptor 0.0008 0.0032 0.0053
Leishmania major aldo-keto reductase-like protein 0.0017 0.0129 0.1102
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0049 0.0081
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0374 0.0616
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0006 0.0008 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0119 0.1015
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0049 0.0081
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0014 0.0091 0.015
Echinococcus granulosus hyperpolarization activated cyclic 0.0006 0 0.0001
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.005 0.0476 0.1508
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0114 0.1169 0.9629
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0102 0.0877
Echinococcus multilocularis aldo keto reductase 0.0017 0.0129 0.0212
Mycobacterium leprae putative cytochrome p450 0.0008 0.0022 0.0022
Schistosoma mansoni DNA topoisomerase II 0.0028 0.0247 0.0406
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0457 0.1762
Entamoeba histolytica protein kinase, putative 0.002 0.0157 0.0833
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0453 0.3877
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0098 0.0835
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0526 0.0865
Loa Loa (eye worm) hypothetical protein 0.0107 0.1092 0.421
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Echinococcus multilocularis serotonin transporter 0.0082 0.0822 0.1354
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0008 0.0022 0.0023
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0031 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0092 0.0927 0.3575
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0374 0.0616
Schistosoma mansoni GST class-mu 0.0027 0.0229 0.0378
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0032 0.0053
Loa Loa (eye worm) latrophilin receptor protein 2 0.0055 0.0531 0.2047
Brugia malayi intermediate filament protein 0.0008 0.0024 0.0094
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0053
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0014 0.0091 0.0777
Echinococcus granulosus prostaglandin H2 D isomerase 0.0119 0.1213 0.1998
Echinococcus multilocularis hyperpolarization activated cyclic 0.0006 0 0.0001
Schistosoma mansoni acetolactate synthase 0.0033 0.0296 0.0488
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0028 0.0247 0.0951
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0012 0.0075 0.0643
Plasmodium vivax ataxin-2 like protein, putative 0.0013 0.0085 0.0641
Mycobacterium leprae PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT) ILVB (ACETOHYDROXY-ACID SYNTHASE) 0.0039 0.0357 0.0357
Echinococcus multilocularis glutathione S transferase 0.0027 0.0229 0.0378
Leishmania major cytochrome p450-like protein 0.0008 0.0022 0.0188
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0008 0.0032 0.0123
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.1239 0.1281
Echinococcus granulosus serotonin receptor 0.0008 0.0032 0.0053
Echinococcus granulosus FTZ F1 alpha 0.001 0.0049 0.0081
Schistosoma mansoni growth factor receptor-bound protein 0.0036 0.0325 0.0536
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0031 0.0273 0.1054
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0152 0.025
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Brugia malayi MH2 domain containing protein 0.0049 0.0472 0.1821
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus 7TM GPCR rhodopsin 0.0008 0.0032 0.0053
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0012 0.0075 0.0643
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.01 0.1009 0.1043
Plasmodium falciparum serine/threonine protein kinase, putative 0.0114 0.1169 1
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0053
Entamoeba histolytica aldose reductase, putative 0.0017 0.0129 0.0683
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0014 0.0091 0.015
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus glutathione S transferase 0.0006 0.0007 0.0012
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0072 0.0276
Leishmania major phosphopantetheinyl transferase-like protein 0.0015 0.0102 0.0877
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0049 0.0189
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0016 0.0108 0.0417
Schistosoma mansoni pol-related 0.0017 0.0129 0.0212
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0081 0.0806 0.1328
Echinococcus multilocularis L aminoadipate semialdehyde 0.0053 0.0515 0.0847
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0017 0.0129 0.0497
Plasmodium vivax geranylgeranyltransferase, putative 0.0021 0.0169 0.1345
Toxoplasma gondii hypothetical protein 0.0042 0.0388 0.3319
Mycobacterium tuberculosis Probable oxalyl-CoA decarboxylase OxcA 0.0039 0.0357 0.0369
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0031 0.0273 0.045
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Echinococcus granulosus protein kinase c epsilon type 0.0008 0.0026 0.0043
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0056 0.0544 0.1724
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0008 0.0032 0.0053
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0181 0.1886 0.5977
Echinococcus granulosus voltage dependent calcium channel 0.0092 0.0927 0.1526
Plasmodium falciparum DNA gyrase subunit B 0.0009 0.0042 0.0297
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0053
Trypanosoma brucei DNA topoisomerase ii 0.0022 0.0181 0.1553
Loa Loa (eye worm) AGC/NDR protein kinase 0.0008 0.0026 0.0101
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0008 0.0032 0.0053
Brugia malayi Glutathione S-transferase 4 0.0021 0.0163 0.063
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0056 0.0544 0.0896
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0006 0 0.0001
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0056 0.0544 0.4624
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0056 0.0541 0.4628
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0026 0.0043
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0119 0.1015
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0031 0.0273 0.2205
Echinococcus granulosus glutathione s transferase mu 0.0027 0.0229 0.0378
Mycobacterium leprae conserved hypothetical protein 0.0015 0.0102 0.0102
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0049 0.0081
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0014 0.0091 0.035
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0008 0.0022 0.0023
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0015 0.0102 0.079
Schistosoma mansoni lipoxygenase 0.0055 0.0531 0.0875
Mycobacterium ulcerans hypothetical protein 0.0013 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0053
Plasmodium falciparum geranylgeranyltransferase, putative 0.0021 0.0169 0.1397
Onchocerca volvulus 0.0017 0.0129 0.0408
Onchocerca volvulus 0.0008 0.0032 0.0101
Mycobacterium ulcerans aldehyde dehydrogenase 0.01 0.1009 0.1009
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0006 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0236 0.2468 0.952
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0119 0.0376
Loa Loa (eye worm) oxidoreductase 0.0017 0.0129 0.0497
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0008 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0056 0.0544 0.2099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0053
Schistosoma mansoni opsin-like receptor 0.0008 0.0032 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Brugia malayi Melatonin receptor type 1A 0.0008 0.0032 0.0123
Mycobacterium ulcerans acetolactate synthase large subunit IlvB 0.0022 0.0179 0.0179
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0015 0.0098 0.0835
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0006 0 0.0001
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0181 0.1886 1
Plasmodium falciparum plasmepsin I 0.0018 0.0132 0.1078
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0026 0.0083
Loa Loa (eye worm) hypothetical protein 0.0014 0.0091 0.035
Onchocerca volvulus 0.0008 0.0032 0.0101
Brugia malayi G-protein coupled receptor 0.0008 0.0032 0.0123
Schistosoma mansoni hypothetical protein 0.0055 0.0531 0.0874
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0032 0.0053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0073 0.0725 0.2298
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0008 0.0022 0.0022
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0008 0.0026 0.0101
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0115 0.1172 0.193
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0055 0.0531 0.0874
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Schistosoma mansoni hypothetical protein 0.0115 0.1172 0.193
Toxoplasma gondii hypothetical protein 0.0014 0.0091 0.0777
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0032 0.0286 0.1102
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Echinococcus granulosus hypothetical protein 0.0017 0.0129 0.0212
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0152 0.12
Trichomonas vaginalis AGC family protein kinase 0.0114 0.1169 0.3703
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0015 0.0098 0.0778
Brugia malayi hypothetical protein 0.0115 0.1172 0.4521
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0014 0.009 0.0772
Schistosoma mansoni atypical protein kinase C 0.0008 0.0026 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Loa Loa (eye worm) AUR protein kinase 0.0114 0.1169 0.4507
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0181 0.1886 0.5977
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0021 0.0163 0.0516
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0049 0.0189
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0021 0.0169 0.1397
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0008 0.0032 0.0123
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0181 0.1886 0.5977
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0032 0.0053
Brugia malayi Cytochrome P450 family protein 0.0008 0.0022 0.0085
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0049 0.0081
Mycobacterium ulcerans oxidoreductase 0.0017 0.0129 0.0129
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0049 0.0156
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0021 0.0169 0.0654
Echinococcus multilocularis microtubule associated protein 2 0.0572 0.6073 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0014 0.0091 0.015
Leishmania major elongation factor-1 gamma 0.0006 0.0007 0.0062
Trichomonas vaginalis set domain proteins, putative 0.03 0.3156 1
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0032 0.0053
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0049 0.0189
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0055 0.0531 0.0874
Echinococcus granulosus orexin receptor type 2 0.0008 0.0032 0.0053
Schistosoma mansoni opsin-like receptor 0.0008 0.0032 0.0053
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0119 0.1015
Brugia malayi Cytochrome P450 family protein 0.0008 0.0022 0.0085
Brugia malayi cytochrome P450 0.0008 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0014 0.0091 0.035
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0021 0.0169 0.1345
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0049 0.0081
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0032 0.0053
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0012 0.0075 0.0643
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0008 0.0022 0.0023
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0009 0.0042 0.0508
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0006 0 0.0001
Plasmodium falciparum DNA topoisomerase 2 0.0028 0.0247 0.2062
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0012 0.0075 0.0643
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Schistosoma mansoni cathepsin D (A01 family) 0.0053 0.0505 0.0832
Brugia malayi G protein-coupled receptor F59B2.13 0.0008 0.0032 0.0123
Brugia malayi Intermediate filament tail domain containing protein 0.0008 0.0024 0.0094
Trichomonas vaginalis AGC family protein kinase 0.002 0.0157 0.0498
Loa Loa (eye worm) hypothetical protein 0.0013 0.0076 0.0294
Plasmodium falciparum plasmepsin IV 0.0018 0.0132 0.1078
Schistosoma mansoni loxhd1 0.002 0.0152 0.025
Schistosoma mansoni survival motor neuron protein 0.0048 0.0457 0.0752
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0453 0.0746
Onchocerca volvulus 0.0053 0.0515 0.163
Trypanosoma cruzi Wee1-like protein kinase, putative 0.0014 0.0086 0.0738
Echinococcus granulosus alpha 1A adrenergic receptor 0.0008 0.0032 0.0053
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0008 0.0022 0.0022
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0014 0.0091 0.015
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0056 0.0544 0.2099
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0114 0.1169 0.6196
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0008 0.0022 0.0023
Brugia malayi Protein kinase domain containing protein 0.0188 0.1957 0.7549
Echinococcus granulosus GPCR family 2 0.0055 0.0531 0.0874
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0053
Trypanosoma brucei hypothetical protein, conserved 0.0006 0.0007 0.0062
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0152 0.025
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0015 0.0098 0.0161
Onchocerca volvulus 0.001 0.0049 0.0156
Echinococcus granulosus tachykinin peptides receptor 99D 0.0008 0.0032 0.0053
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0017 0.012 0.012
Toxoplasma gondii transporter, cation channel family protein 0.0032 0.0288 0.2469
Giardia lamblia Rab geranylgeranyltransferase 0.0056 0.0544 0.2885
Leishmania major cytochrome p450-like protein 0.0008 0.0022 0.0188
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Toxoplasma gondii aspartyl protease ASP1 0.0018 0.0132 0.1134
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0453 0.1747
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0017 0.0129 0.0408
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0053
Echinococcus multilocularis GPCR, family 2 0.0055 0.0531 0.0874
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0014 0.0091 0.015
Brugia malayi RNA binding protein 0.0032 0.0286 0.1102
Brugia malayi nuclear receptor NHR-88 0.001 0.0049 0.0189
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0056 0.0544 0.2885
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.005 0.0476 0.2523
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0021 0.0169 0.0279
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0014 0.0091 0.0777
Onchocerca volvulus 0.002 0.0152 0.0482
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Mycobacterium leprae Probable Acetolactate synthase IlvG (Acetohydroxy-acid synthase)(ALS) 0.0039 0.0357 0.0357
Leishmania major geranylgeranyltransferase, putative 0.0021 0.0169 0.145
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.01 0.1009 0.1661
Echinococcus multilocularis g-protein coupled receptor 0.0008 0.0032 0.0053
Leishmania major C-8 sterol isomerase-like protein 0.0107 0.1092 0.934
Echinococcus multilocularis G protein coupled receptor 139 0.0008 0.0032 0.0053
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0181 0.1886 0.5977
Schistosoma mansoni cytochrome P450 0.0008 0.0022 0.0036
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0053
Echinococcus granulosus neuropeptide receptor 0.0008 0.0032 0.0053
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0008 0.0032 0.0053
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0119 0.1015
Loa Loa (eye worm) glutathione reductase 0.0048 0.0453 0.1747
Echinococcus multilocularis rac serine:threonine kinase 0.0014 0.009 0.0149
Onchocerca volvulus 0.0008 0.0032 0.0101
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0008 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0092 0.0927 0.3575
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0119 0.1015
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0021 0.0169 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0008 0.0022 0.0023
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.1109 0.1147
Giardia lamblia Prenyltransferase 0.005 0.0476 0.2523
Loa Loa (eye worm) hypothetical protein 0.0011 0.0061 0.0236
Plasmodium vivax farnesyltransferase beta subunit, putative 0.005 0.0476 0.3886
Brugia malayi hypothetical protein 0.0013 0.0085 0.0326
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0008 0.0032 0.0053
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0021 0.0169 0.145
Onchocerca volvulus 0.0008 0.0032 0.0101
Onchocerca volvulus 0.0123 0.1261 0.3997
Echinococcus multilocularis glutathione s transferase mu 0.0027 0.0229 0.0378
Trypanosoma cruzi aldo-keto reductase 0.0017 0.0129 0.1102
Echinococcus granulosus microtubule associated protein 2 0.0572 0.6073 1
Mycobacterium ulcerans acetolactate synthase 1 catalytic subunit 0.0039 0.0357 0.0357
Onchocerca volvulus 0.0014 0.0091 0.0288
Trypanosoma cruzi Protein kinase B 0.0014 0.009 0.0772
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Loa Loa (eye worm) AGC/PKN protein kinase 0.0008 0.0026 0.0101
Onchocerca volvulus 0.0014 0.0091 0.0288
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0008 0.0022 0.0022
Echinococcus granulosus growth factor receptor bound protein 2 0.0036 0.0325 0.0536
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0129 0.0212
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0017 0.0129 0.0497
Entamoeba histolytica protein kinase 2, putative 0.0014 0.009 0.0479
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0008 0.0022 0.0022
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0015 0.0098 0.0835
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0073 0.0725 0.2298
Onchocerca volvulus 0.0014 0.0091 0.0288
Onchocerca volvulus 0.0017 0.0129 0.0408
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0014 0.0091 0.035
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0017 0.012 0.0124
Onchocerca volvulus 0.0008 0.0024 0.0077
Brugia malayi Calcitonin receptor-like protein seb-1 0.0174 0.1804 0.6959
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0026 0.0083
Onchocerca volvulus 0.0008 0.0032 0.0101
Schistosoma mansoni cathepsin D (A01 family) 0.0053 0.0505 0.0832
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0031 0.0273 0.2338
Entamoeba histolytica pyruvate:ferredoxin oxidoreductase 0.0006 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Trypanosoma cruzi DNA topoisomerase II, putative 0.0026 0.0216 0.1848
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0119 0.0959
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0006 0 0.0001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0119 1
Brugia malayi hypothetical protein 0.002 0.0152 0.0586
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0119 0.0123
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0008 0.0022 0.0022
Toxoplasma gondii cytochrome p450 superfamily protein 0.0008 0.0022 0.0188
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0008 0.0022 0.0023
Plasmodium vivax plasmepsin IV, putative 0.0018 0.0132 0.1038
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0049 0.0081
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0018 0.0132 0.1134
Plasmodium vivax DNA topoisomerase II, putative 0.0028 0.0247 0.1985
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0092 0.0927 0.1526
Mycobacterium tuberculosis Probable oxidoreductase (beta subunit) 0.0006 0.0002 0.0002
Schistosoma mansoni sodium-dependent amino acid transporter 0.0014 0.0091 0.015
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0189
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0014 0.0091 0.015
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0014 0.0091 0.6386
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0008 0.0026 0.0101
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0022 0.0188
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0008 0.0022 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0075 0.0745 0.2359
Loa Loa (eye worm) hypothetical protein 0.0119 0.1215 0.4686
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0053
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0014 0.0086 0.0738
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0008 0.0026 0.0101
Schistosoma mansoni rab6-interacting 0.002 0.0152 0.025
Entamoeba histolytica PH domain containing protein kinase, putative 0.0014 0.009 0.0479
Brugia malayi Thiamine pyrophosphate enzyme, central domain containing protein 0.0039 0.0357 0.1375
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0107 0.1092 0.421
Echinococcus granulosus glutathione S transferase 0.0027 0.0229 0.0378
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0119 0.1213 0.1998
Loa Loa (eye worm) hypothetical protein 0.0021 0.0169 0.0654
Echinococcus granulosus sodium and chloride dependent glycine 0.0014 0.0091 0.015
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0129 0.0212
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.0032 0.0053
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0006 0.0009 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0008 0.0022 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0073 0.0725 0.2298
Brugia malayi follicle stimulating hormone receptor 0.0008 0.0032 0.0123
Entamoeba histolytica PH domain containing protein kinase, putative 0.0014 0.009 0.0479
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0008 0.0022 0.0022
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0031 0.0273 0.1054
Loa Loa (eye worm) MH2 domain-containing protein 0.0049 0.0472 0.1821
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0006 0.0006 0.0009
Trichomonas vaginalis AGC family protein kinase 0.002 0.0157 0.0498
Trypanosoma brucei protein farnesyltransferase beta subunit 0.005 0.0476 0.4073
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0152 0.025
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0109 0.0179
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0031 0.0273 0.1448
Loa Loa (eye worm) hypothetical protein 0.0014 0.0091 0.035
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0119 0.0119
Schistosoma mansoni myosin xvIII 0.0008 0.0032 0.0053
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0049 0.0189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0053
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0152 0.025
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Schistosoma mansoni tar DNA-binding protein 0.0032 0.0286 0.047
Trypanosoma brucei wee1-like protein kinase 0.0014 0.0086 0.0738
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0014 0.0091 0.035
Echinococcus multilocularis serine:threonine protein kinase N2 0.0008 0.0026 0.0043
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0129 0.0212
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0081 0.0806 0.311
Echinococcus granulosus aldo keto reductase 0.0017 0.0129 0.0212
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0049 0.0081
Trichomonas vaginalis aldo/keto reductase, putative 0.0017 0.0129 0.0408
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0018 0.0132 0.0218
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0053
Onchocerca volvulus 0.0008 0.0024 0.0077
Echinococcus multilocularis aldehyde reductase 0.0012 0.0074 0.0123
Echinococcus multilocularis aldo keto reductase 0.0017 0.0129 0.0212
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0169 0.145
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0073 0.0725 0.2298
Echinococcus multilocularis dro:myosuppressin receptor 0.0008 0.0032 0.0053
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0008 0.0022 0.0022
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0008 0.0032 0.0123
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.2468 0.4065
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0073 0.0725 0.3844
Echinococcus multilocularis aurora kinase A 0.0114 0.1169 0.1924
Plasmodium falciparum acyl-CoA synthetase 0.0022 0.0179 0.1478
Brugia malayi hypothetical protein 0.0014 0.0091 0.035
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0114 0.1169 0.6196
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus nervana 2 0.0012 0.0072 0.0119
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0032 0.0053
Brugia malayi Dopamine receptor protein 1 0.0008 0.0032 0.0123
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0025
Plasmodium vivax aspartyl proteinase, putative 0.0018 0.0132 0.1038
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0053
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0006 0.0009 0.0014
Toxoplasma gondii AGC kinase 0.002 0.0157 0.1344
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0919 0.3544
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0032 0.0123
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0092 0.0927 0.1526
Mycobacterium tuberculosis Probable reductase 0.0109 0.1109 0.1147
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0008 0.0032 0.0123
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0919 0.1513
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Plasmodium vivax glutathione reductase, putative 0.0048 0.0453 0.3696
Loa Loa (eye worm) solute carrier family 6 member 4 0.0082 0.0822 0.3172
Echinococcus multilocularis sex peptide receptor 0.0008 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0081 0.0806 0.1328
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.0526 0.0865
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0006 0 0.0001
Trichomonas vaginalis pyruvate-flavodoxin oxidoreductase, putative 0.0006 0.0002 0.0005
Echinococcus multilocularis lamin 0.0008 0.0024 0.004
Schistosoma mansoni acetolactate synthase 0.0033 0.0296 0.0488
Loa Loa (eye worm) hypothetical protein 0.0021 0.0169 0.0654
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0054 0.0526 0.4497
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0092 0.0927 0.1526
Brugia malayi RNA recognition motif domain containing protein 0.0032 0.0286 0.1102
Mycobacterium tuberculosis Probable oxidoreductase 0.0017 0.0129 0.0133
Loa Loa (eye worm) hypothetical protein 0.0008 0.0023 0.0088
Loa Loa (eye worm) hypothetical protein 0.0008 0.0024 0.0094
Brugia malayi GnHR receptor homolog 0.0008 0.0032 0.0123
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0008 0.0032 0.0123
Onchocerca volvulus 0.0008 0.0032 0.0101
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0119 0.0376
Schistosoma mansoni microtubule-associated protein tau 0.0572 0.6073 1
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0031 0.0273 0.2338
Echinococcus granulosus fmrfamide receptor 0.0008 0.0032 0.0053
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0008 0.0022 0.0022
Loa Loa (eye worm) doublecortin family protein 0.002 0.0152 0.0586
Loa Loa (eye worm) hypothetical protein 0.0105 0.107 0.4125
Schistosoma mansoni transcription factor LCR-F1 0.0115 0.1172 0.193
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0015 0.0098 0.0376
Treponema pallidum pyruvate oxidoreductase 0.0006 0.0002 0.002
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0022 0.0188
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0014 0.0091 0.035
Brugia malayi hypothetical protein 0.0236 0.2468 0.952
Echinococcus multilocularis serotonin receptor 0.004 0.0374 0.0616
Schistosoma mansoni coup transcription factor 0.001 0.0049 0.0081
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0031 0.0273 0.2338
Schistosoma mansoni thyroid hormone receptor 0.001 0.0049 0.0081
Onchocerca volvulus 0.0008 0.0032 0.0101
Brugia malayi Dopamine receptor protein 2 0.0008 0.0032 0.0123
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0008 0.0022 0.0023
Echinococcus granulosus tm gpcr rhodopsin 0.0216 0.2262 0.3724
Onchocerca volvulus 0.0082 0.0822 0.2606
Schistosoma mansoni serine/threonine-protein kinase 0.0014 0.009 0.0149
Echinococcus granulosus geminin 0.0169 0.1752 0.2885
Trypanosoma brucei rac serine-threonine kinase, putative 0.002 0.0157 0.1344
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0181 0.1886 0.7274
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0014 0.0091 0.015
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0073 0.0725 0.3844
Schistosoma mansoni elongation factor 1-gamma 0.0006 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Treponema pallidum sodium- and chloride- dependent transporter 0.0082 0.0822 1
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0032 0.0053
Loa Loa (eye worm) serotonin transporter b 0.0082 0.0822 0.3172
Brugia malayi Cyclic-nucleotide gated cation channel 0.0006 0 0.0001
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0032 0.0053
Loa Loa (eye worm) CYP4Cod1 0.0008 0.0022 0.0085
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0152 0.025
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0021 0.0169 0.0175
Echinococcus multilocularis aldo keto reductase 0.0017 0.0129 0.0212
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0026 0.0083
Brugia malayi Hr1 repeat family protein 0.0008 0.0026 0.0101
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0017 0.0129 0.0497
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0053
Trichomonas vaginalis DNA topoisomerase II, putative 0.0028 0.0247 0.0782
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0012 0.0075 0.0643
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.005 0.0476 0.4073
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0056 0.0544 0.1724
Loa Loa (eye worm) oxidoreductase 0.0017 0.0129 0.0497
Trypanosoma cruzi Wee1-like protein kinase, putative 0.0014 0.0086 0.0738
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0006 0 0.0001
Brugia malayi serine/threonine kinase 12 0.0114 0.1169 0.4507
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0026 0.0216 0.1848
Toxoplasma gondii elongation factor 1-gamma, putative 0.0006 0.0007 0.0062
Echinococcus multilocularis eukaryotic translation elongation factor 1 0.0006 0.0007 0.0012
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0015 0.0098 0.0835
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Brugia malayi Doublecortin family protein 0.002 0.0152 0.0586
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0119 0.0923
Entamoeba histolytica hypothetical protein 0.0115 0.1172 0.6215
Echinococcus multilocularis calcium activated potassium channel 0.0006 0.0006 0.0011
Schistosoma mansoni hypothetical protein 0.0006 0.0006 0.0009
Mycobacterium ulcerans 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 0.0007 0.0015 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0919 0.1513
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0014 0.0091 0.015
Trypanosoma brucei phosphonopyruvate decarboxylase-like protein, putative 0.0013 0.0075 0.0646
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0015 0.0102 0.0106
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0031 0.0273 0.0273
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0119 0.1015
Brugia malayi neuropeptide F receptor 0.0008 0.0032 0.0123
Brugia malayi Probable DNA topoisomerase II 0.0028 0.0247 0.0951
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0008 0.0032 0.0053
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0006 0 0.0001
Plasmodium vivax glutathione S-transferase, putative 0.0119 0.1213 1
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0015 0.0102 0.8642
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0008 0.0032 0.0053
Leishmania major phosphonopyruvate decarboxylase-like protein 0.0013 0.0075 0.0646
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0129 0.0212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0049 0.0189
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0049 0.0081
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0034
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0036 0.0324 0.0335
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0015 0.0098 0.0161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0049 0.0189
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0014 0.0091 0.015
Onchocerca volvulus 0.0048 0.0457 0.1447
Onchocerca volvulus 0.0008 0.0032 0.0101
Brugia malayi Dopamine receptor 0.0008 0.0032 0.0123
Echinococcus granulosus protein kinase c iota type 0.0008 0.0026 0.0043
Plasmodium vivax acyl-CoA synthetase, putative 0.0022 0.0179 0.1423
Onchocerca volvulus 0.0021 0.0163 0.0518
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0022 0.0085
Schistosoma mansoni growth hormone secretagogue receptor 0.0008 0.0032 0.0053
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0049 0.0189
Trypanosoma cruzi aurora B kinase, putative 0.0114 0.1169 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0012 0.0073 0.0121
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0129 0.0497
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0056 0.0544 0.0896
Trypanosoma cruzi DNA topoisomerase II, putative 0.0026 0.0216 0.1848
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0014 0.0091 0.035
Entamoeba histolytica protein kinase, putative 0.002 0.0157 0.0833
Trichomonas vaginalis glutaminyl-tRNA synthetase, putative 0.0021 0.0163 0.0518
Echinococcus granulosus hypothetical protein 0.0008 0.0032 0.0053
Brugia malayi G protein-coupled receptor 0.0008 0.0032 0.0123
Trichomonas vaginalis pyruvate-flavodoxin oxidoreductase, putative 0.0006 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0216 0.2262 0.3724
Echinococcus multilocularis sodium and chloride dependent glycine 0.0014 0.0091 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0049 0.0189
Onchocerca volvulus 0.0015 0.0098 0.0309
Loa Loa (eye worm) hypothetical protein 0.0028 0.0241 0.0931
Trypanosoma cruzi phosphonopyruvate decarboxylase, putative 0.0013 0.0075 0.0646
Schistosoma mansoni hypothetical protein 0.0169 0.1752 0.2885
Echinococcus granulosus serine:threonine protein kinase N2 0.0008 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0006 0 0.0001
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.005 0.0476 0.0784
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0008 0.0024 0.0094
Trypanosoma brucei calpain, putative 0.0012 0.0075 0.0643
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.005 0.0476 0.1508
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0008 0.0032 0.0123
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0031 0.0273 0.0866
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0015 0.0102 0.082
Echinococcus multilocularis hyperpolarization activated cyclic 0.0006 0 0.0001
Trichomonas vaginalis pyruvate-flavodoxin oxidoreductase, putative 0.0006 0.0002 0.0005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0032 0.0053
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0014 0.0091 0.015
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0119 0.0959
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0031 0.0273 0.229
Schistosoma mansoni biogenic amine receptor 0.0008 0.0032 0.0053
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0021 0.0163 0.0516
Brugia malayi Pre-SET motif family protein 0.0054 0.0526 0.2027
Echinococcus multilocularis serine threonine protein kinase 0.0008 0.0026 0.0043
Schistosoma mansoni adenoreceptor 0.0008 0.0032 0.0053
Trypanosoma brucei prostaglandin f synthase 0.0017 0.0129 0.1102
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0014 0.0091 0.015
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0015 0.0102 0.0102
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0031 0.0273 0.0283
Brugia malayi Cytochrome P450 family protein 0.0008 0.0022 0.0085
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0008 0.0026 0.0043
Brugia malayi nuclear hormone receptor 0.001 0.0049 0.0189
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0009 0.0042 0.0357
Brugia malayi protein kinase C II. 0.0008 0.0026 0.0101
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.005 0.0476 0.1508
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0008 0.0032 0.0123
Leishmania major DNA topoisomerase ii 0.0026 0.0216 0.1848
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0006 0 0.0001
Echinococcus granulosus somatostatin receptor 0.0008 0.0032 0.0053
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0022 0.0181 0.1553
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0049 0.0081
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0015 0.0102 0.7904
Echinococcus multilocularis glutathione S transferase 0.0021 0.0163 0.0269
Loa Loa (eye worm) oxidoreductase 0.0017 0.0129 0.0497
Toxoplasma gondii aldose reductase, putative 0.0017 0.0129 0.1102
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0026 0.0043
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0055 0.0531 0.0874
Echinococcus multilocularis aldo keto reductase 0.0017 0.0129 0.0212
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0227 0.2376 0.3912
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0119 0.0195
Loa Loa (eye worm) hypothetical protein 0.0082 0.0822 0.3172
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0053
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0132 0.0218
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0008 0.0026 0.0043
Loa Loa (eye worm) AUR protein kinase 0.0114 0.1169 0.4507
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0017 0.012 0.012
Loa Loa (eye worm) norepinephrine transporter 0.0082 0.0822 0.3172
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0082 0.0134
Schistosoma mansoni hypothetical protein 0.0055 0.0531 0.0874
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0049 0.0189
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0453 0.0746
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0042 0.0388 0.1229
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.01 0.1009 0.1661
Trichomonas vaginalis AGC family protein kinase 0.0114 0.1169 0.3703
Plasmodium falciparum amino acid transporter, putative 0.0014 0.0091 0.072
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0049 0.0081
Trypanosoma cruzi phosphonopyruvate decarboxylase, putative 0.0013 0.0075 0.0646
Loa Loa (eye worm) calcium channel 0.0092 0.0927 0.3575
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0012 0.0073 0.0282
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0032 0.0053
Onchocerca volvulus 0.0008 0.0032 0.0101
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Schistosoma mansoni hypothetical protein 0.0119 0.1215 0.2001
Schistosoma mansoni hypothetical protein 0.0019 0.0146 0.0241
Brugia malayi putative neuropeptide receptor NPR1 0.0008 0.0032 0.0123
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0119 0.1015
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0006 0 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0022 0.0085
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0174 0.1804 0.6959
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0015 0.0098 0.0835
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0009 0.0042 0.0043
Plasmodium falciparum plasmepsin II 0.0018 0.0132 0.1078
Schistosoma mansoni histamine h1 receptor 0.0008 0.0032 0.0053
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0031 0.0273 0.2338
Brugia malayi sulfakinin receptor protein 0.0008 0.0032 0.0123
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0189
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0919 0.1513
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Leishmania major hypothetical protein, conserved 0.0056 0.0541 0.4628
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0012 0.0075 0.0643
Schistosoma mansoni hypothetical protein 0.0055 0.0531 0.0874
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus aldo keto reductase 0.0017 0.0129 0.0212
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0015 0.0098 0.0309
Loa Loa (eye worm) hypothetical protein 0.0065 0.064 0.2467
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0008 0.0032 0.0123
Trypanosoma brucei lanosterol synthase 0.0021 0.0169 0.145
Leishmania major prostaglandin f synthase, putative 0.0017 0.0129 0.1102
Schistosoma mansoni voltage-gated potassium channel 0.0006 0 0.0001
Giardia lamblia Kinase, AGC PKA 0.0014 0.009 0.0479
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0015 0.0098 0.0749
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.005 0.0476 0.1508
Mycobacterium leprae PROBABLE BIFUNCTIONAL MENAQUINONE BIOSYNTHESIS PROTEIN MEND : 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE (SH 0.0007 0.0015 0.0015
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus serotonin transporter 0.0082 0.0822 0.1354
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0169 0.145
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0049 0.0156
Brugia malayi Sex muscle abnormal protein 5 0.0036 0.0325 0.1254
Onchocerca volvulus 0.0181 0.1886 0.5977
Echinococcus multilocularis lamin dm0 0.0008 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0014 0.0091 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0049 0.0189
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0049 0.0081
Brugia malayi Pre-SET motif family protein 0.0247 0.2593 1
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0008 0.0022 0.0188
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0031 0.0273 0.2338
Loa Loa (eye worm) hypothetical protein 0.004 0.0374 0.1443
Entamoeba histolytica hypothetical protein 0.0115 0.1172 0.6215
Echinococcus multilocularis glutathione S transferase 0.0006 0.0007 0.0012
Loa Loa (eye worm) transcription factor SMAD2 0.0049 0.0472 0.1821
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0015 0.0098 0.0517
Plasmodium vivax ubiquitin activating enzyme, putative 0.0006 0.0009 0.0018
Brugia malayi Protein kinase domain containing protein 0.002 0.0157 0.0606
Schistosoma mansoni intermediate filament proteins 0.0008 0.0024 0.004
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0012 0.0075 0.0643
Schistosoma mansoni sodium/chloride dependent transporter 0.0014 0.0091 0.015
Echinococcus granulosus intermediate filament protein 0.0008 0.0024 0.004
Trypanosoma brucei cytochrome P450, putative 0.0008 0.0022 0.0188
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0008 0.0032 0.0053
Mycobacterium ulcerans DNA gyrase subunit B 0.0009 0.0042 0.0042
Echinococcus multilocularis neuropeptide FF receptor 2 0.0008 0.0032 0.0053
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0012 0.0075 0.0643
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0008 0.0022 0.0022
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0008 0.0032 0.0053
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0049 0.0081
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0017 0.0129 0.0408
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0107 0.1092 0.934
Echinococcus granulosus peptide allatostatin:somatostatin 0.0008 0.0032 0.0053
Echinococcus multilocularis 0.0008 0.0022 0.0036
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.0526 0.0865
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0092 0.0927 0.1526
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0026 0.0043
Trypanosoma brucei elongation factor 1 gamma, putative 0.0006 0.0007 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0008 0.0022 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0032 0.0286 0.047
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0119 0.1015
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0008 0.0026 0.0043
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0015 0.0098 0.0376
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0032 0.0123
Schistosoma mansoni serine/threonine kinase 0.0008 0.0026 0.0043
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0014 0.009 0.0149
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0032 0.0053
Brugia malayi Thioredoxin reductase 0.0048 0.0453 0.1747
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0181 0.1886 0.5977
Brugia malayi AKH receptor 0.0008 0.0032 0.0123
Echinococcus multilocularis glutathione S transferase 0.0006 0.0007 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0541 0.4628
Echinococcus granulosus L aminoadipate semialdehyde 0.0053 0.0515 0.0847
Mycobacterium ulcerans putative oxalyl-CoA decarboxylase 0.0039 0.0357 0.0357
Trichomonas vaginalis AGC family protein kinase 0.0114 0.1169 0.3703
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0021 0.0169 0.145
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0008 0.0022 0.0023
Trichomonas vaginalis aldo/keto reductase, putative 0.0017 0.0129 0.0408
Brugia malayi ThiF family protein 0.0006 0.0009 0.0036
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0021 0.0169 0.145
Echinococcus granulosus Protein kinase C brain isozyme 0.0008 0.0026 0.0043
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0031 0.0273 0.045
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0008 0.0026 0.0101
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0241 0.0931
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0015 0.0102 0.0877
Giardia lamblia Aldose reductase 0.0017 0.0129 0.0683
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0014 0.0091 0.035
Echinococcus multilocularis dnaJ subfamily B 0.0019 0.0146 0.0241
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0032 0.0053
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0032 0.0053
Brugia malayi Serotonin receptor 0.0008 0.0032 0.0123
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0036 0.0325 0.1254
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0032 0.0053
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Plasmodium falciparum transporter, putative 0.0014 0.0091 0.072
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0026 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.1957 0.3223
Echinococcus granulosus g protein coupled receptor 0.0008 0.0032 0.0053
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0015 0.0102 0.0102
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0014 0.009 0.0688
Echinococcus granulosus serine threonine protein kinase nrc 0.0014 0.009 0.0149
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0119 0.1015
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.1109 0.1147
Echinococcus multilocularis glutathione S transferase 0.0027 0.0229 0.0378
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.005 0.0476 0.1508
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus nervana 2 0.0012 0.0072 0.0119
Plasmodium falciparum glutathione reductase 0.0048 0.0453 0.3838
Leishmania major trypanothione reductase 0.0048 0.0453 0.3877
Schistosoma mansoni sodium/chloride dependent transporter 0.0082 0.0822 0.1354
Loa Loa (eye worm) hypothetical protein 0.0014 0.0091 0.035
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0049 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0114 0.1169 0.3703
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0081 0.0806 0.4276
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0006 0.0009 0.0015
Schistosoma mansoni aldo-keto reductase 0.0017 0.0129 0.0212
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0006 0 0.0001
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0129 0.0212
Chlamydia trachomatis DNA gyrase subunit B 0.0015 0.0107 0.8492
Mycobacterium ulcerans pyruvate or indole-3-pyruvate decarboxylase Pdc 0.0022 0.0179 0.0179
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Leishmania major farnesyltransferase beta subunit 0.005 0.0476 0.4073
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0919 0.1513
Onchocerca volvulus 0.03 0.3156 1
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0017 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0014 0.0091 0.035
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0453 0.3696
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Plasmodium falciparum ataxin-2 like protein, putative 0.0013 0.0085 0.0666
Plasmodium falciparum ataxin-2 like protein, putative 0.0013 0.0085 0.0666
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0129 0.0212
Echinococcus granulosus NDR protein kinase 0.0008 0.0026 0.0043
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0017 0.0129 0.0497
Trichomonas vaginalis AGC family protein kinase 0.002 0.0157 0.0498
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0119 0.1015
Leishmania major hypothetical protein, conserved 0.0013 0.0085 0.0723
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0008 0.0032 0.0053
Plasmodium falciparum protein farnesyltransferase subunit beta 0.005 0.0476 0.4036
Brugia malayi steroid hormone receptor 0.001 0.0049 0.0189
Toxoplasma gondii DNA topoisomerase 2, putative 0.0028 0.0247 0.2111
Echinococcus granulosus neuropeptide s receptor 0.0008 0.0032 0.0053
Trypanosoma cruzi protein farnesyltransferase, putative 0.005 0.0476 0.4073
Trypanosoma brucei aldo-keto reductase, putative 0.0017 0.0129 0.1102
Echinococcus multilocularis voltage gated potassium channel 0.0006 0.0009 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0012 0.0075 0.0643
Onchocerca volvulus 0.0008 0.0032 0.0101
Brugia malayi serine/threonine-protein kinase 6 0.0114 0.1169 0.4507
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0189
Toxoplasma gondii hypothetical protein 0.0028 0.0241 0.2065
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0119 0.1015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0049 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0073 0.0725 0.2298
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0114 0.1169 0.1924
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0008 0.0022 0.0022
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0129 0.0212
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0017 0.012 0.0198
Loa Loa (eye worm) hypothetical protein 0.0019 0.0146 0.0564
Echinococcus multilocularis neuropeptide receptor A26 0.0008 0.0032 0.0053
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0036 0.0324 0.0324
Leishmania major protein kinase, putative 0.0114 0.1169 1
Schistosoma mansoni tar DNA-binding protein 0.0032 0.0286 0.047
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0032 0.0053
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0032 0.0053
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.1109 0.1147
Echinococcus granulosus aldo keto reductase 0.0017 0.0129 0.0212
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0032 0.0053
Leishmania major cytochrome p450-like protein 0.0008 0.0022 0.0188
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0008 0.0026 0.0043
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.1239 0.1239
Schistosoma mansoni opsin-like receptor 0.0008 0.0032 0.0053
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0006 0.0005 0.0008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0008 0.0032 0.0053
Trypanosoma cruzi PAB1-binding protein , putative 0.0013 0.0085 0.0723
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0119 0.0119
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0082 0.0822 0.1354
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0009 0.0042 0.3521
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0015 0.0098 0.0161
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0021 0.0169 0.0537
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0008 0.0022 0.0022
Plasmodium falciparum thioredoxin reductase 0.0017 0.0119 0.0959
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0012 0.0075 0.0643
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0028 0.0247 0.0406
Brugia malayi TAR-binding protein 0.0032 0.0286 0.1102
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.005 0.0476 0.1836
Loa Loa (eye worm) melatonin receptor type 1A 0.0008 0.0032 0.0123
Onchocerca volvulus 0.002 0.0152 0.0482
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.1239 0.1281
Entamoeba histolytica aldose reductase, putative 0.0017 0.0129 0.0683
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0025
Onchocerca volvulus 0.0008 0.0032 0.0101
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0022 0.0181 0.1553
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0031 0.0273 0.045
Onchocerca volvulus 0.0008 0.0032 0.0101
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0022 0.0036
Plasmodium falciparum thioredoxin reductase 0.0048 0.0453 0.3838
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Entamoeba histolytica hypothetical protein 0.0115 0.1172 0.6215
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0049 0.0189
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0919 0.1513
Trichomonas vaginalis AGC family protein kinase 0.002 0.0157 0.0498
Echinococcus multilocularis somatostatin receptor 0.0008 0.0032 0.0053
Brugia malayi hypothetical protein 0.0008 0.0032 0.0123
Echinococcus granulosus neuropeptide receptor 0.0008 0.0032 0.0053
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0053
Brugia malayi Tachykinin-like peptides receptor 99D 0.0008 0.0032 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0049 0.0189
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0008 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0055 0.0529 0.2041
Loa Loa (eye worm) oxidoreductase 0.0017 0.0129 0.0497
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0049 0.0081
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0526 0.0865
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0014 0.0091 0.015
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0017 0.012 0.0464
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0092 0.0927 0.1526
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0053
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0012 0.0075 0.0643
Schistosoma mansoni aldo-keto reductase 0.0017 0.0129 0.0212
Schistosoma mansoni serine/threonine-protein kinase 0.0014 0.009 0.0149
Echinococcus multilocularis G-protein coupled receptor, putative 0.0008 0.0032 0.0053
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0006 0.0007 0.0062
Echinococcus granulosus g protein coupled receptor 0.0008 0.0032 0.0053
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0188 0.1957 0.7549
Brugia malayi Cytochrome P450 family protein 0.0008 0.0022 0.0085
Schistosoma mansoni voltage-gated cation channel 0.0092 0.0927 0.1526
Trypanosoma brucei elongation factor 1 gamma, putative 0.0006 0.0007 0.0062
Echinococcus multilocularis voltage dependent calcium channel 0.0092 0.0927 0.1526
Brugia malayi Protein kinase domain containing protein 0.0008 0.0026 0.0101
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0049 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0049 0.0189
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0189
Onchocerca volvulus 0.0008 0.0032 0.0101
Trypanosoma cruzi protein farnesyltransferase, putative 0.005 0.0476 0.4073
Onchocerca volvulus 0.0017 0.0129 0.0408
Giardia lamblia Rab geranylgeranyltransferase 0.0015 0.0098 0.0517
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0092 0.0927 0.1526
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0092 0.0927 0.1526
Echinococcus multilocularis growth factor receptor bound protein 2 0.0036 0.0325 0.0536
Echinococcus multilocularis musashi 0.0008 0.0024 0.004
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0049 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0026 0.0083
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0008 0.0022 0.0023
Trypanosoma cruzi lanosterol synthase, putative 0.0021 0.0169 0.145
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0012 0.0073 0.0282
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0919 0.1513
Onchocerca volvulus 0.0008 0.0032 0.0101
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0017 0.0129 0.0408
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0008 0.0032 0.0053
Echinococcus granulosus g protein coupled receptor 0.0008 0.0032 0.0053
Echinococcus granulosus glutathione S transferase 0.0092 0.0925 0.1523
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0008 0.0022 0.0022
Loa Loa (eye worm) intermediate filament protein 0.0008 0.0024 0.0094
Toxoplasma gondii LsmAD domain-containing protein 0.0013 0.0085 0.0723
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.1109 0.1147
Plasmodium vivax DNA gyrase subunit B, putative 0.0009 0.0042 0.0286
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0008 0.0026 0.0043
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0055 0.0531 0.0874
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0119 0.1015
Giardia lamblia Aurora kinase 0.0114 0.1169 0.6196
Mycobacterium tuberculosis Probable acetolactate synthase IlvG (acetohydroxy-acid synthase)(ALS) 0.0039 0.0357 0.0369
Brugia malayi RE15519p 0.0008 0.0032 0.0123
Onchocerca volvulus 0.0017 0.0129 0.0408
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0008 0.0032 0.0053
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0008 0.0032 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0189
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0056 0.0541 0.1714
Schistosoma mansoni growth factor receptor-bound protein 0.0036 0.0325 0.0536
Echinococcus multilocularis glutathione S transferase 0.0021 0.0163 0.0269
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0885
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0119 0.1015
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0919 0.3544
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0021 0.0169 0.145
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0008 0.0022 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0091 0.0693
Trichomonas vaginalis AGC family protein kinase 0.002 0.0157 0.0498
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0008 0.0022 0.0022
Brugia malayi putative neuropeptide receptor 0.0008 0.0032 0.0123
Loa Loa (eye worm) TOPoisomerase family member 0.0028 0.0247 0.0951
Echinococcus multilocularis serine:threonine protein kinase 38 0.0008 0.0026 0.0043
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0049 0.0189
Echinococcus multilocularis voltage dependent calcium channel 0.0092 0.0927 0.1526
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0015 0.0102 0.1246
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0008 0.0022 0.0022
Echinococcus granulosus neuropeptide FF receptor 2 0.0008 0.0032 0.0053
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0008 0.0022 0.0188
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0032 0.0053
Leishmania major hypothetical protein, conserved 0.0006 0.0007 0.0062
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0028 0.0247 0.0951
Loa Loa (eye worm) hypothetical protein 0.002 0.0152 0.0586
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0526 0.0865
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0181 0.1886 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0012 0.0075 0.0643
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0053 0.0515 0.0847
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0032 0.0053
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0026 0.0216 0.1848
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0036
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0531 0.0875
Plasmodium falciparum glutathione reductase 0.0017 0.0119 0.0959
Toxoplasma gondii aurora kinase 0.0114 0.1169 1
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0053
Leishmania major mitochondrial DNA topoisomerase II 0.0022 0.0181 0.1553
Toxoplasma gondii thioredoxin reductase 0.0048 0.0453 0.3877
Echinococcus multilocularis nervana 2 0.0012 0.0072 0.0119
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0028 0.0247 0.0406
Onchocerca volvulus 0.0008 0.0032 0.0101
Schistosoma mansoni lamin 0.0008 0.0024 0.004
Brugia malayi ORL1-like opioid receptor 0.0008 0.0032 0.0123
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0008 0.0022 0.0023
Trichomonas vaginalis aldo-keto reductase, putative 0.0017 0.0129 0.0408
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0015 0.0102 0.0877
Entamoeba histolytica protein kinase domain containing protein 0.0114 0.1169 0.6196
Trypanosoma brucei PAB1-binding protein , putative 0.0013 0.0085 0.0723
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0008 0.0032 0.0053
Schistosoma mansoni lipoxygenase 0.002 0.0152 0.025
Echinococcus multilocularis neuropeptide s receptor 0.0008 0.0032 0.0053
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0006 0.0009 0.0015
Schistosoma mansoni nuclear hormone receptor 0.001 0.0049 0.0081
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0015 0.0098 0.0835
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0123
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0032 0.0288 0.2469
Entamoeba histolytica protein kinase , putative 0.0114 0.1169 0.6196
Trichomonas vaginalis pyruvate-flavodoxin oxidoreductase, putative 0.0006 0.0002 0.0005
Brugia malayi hypothetical protein 0.0009 0.0034 0.013
Mycobacterium ulcerans aldehyde dehydrogenase 0.01 0.1009 0.1009
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0022 0.0188
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0181 0.1886 0.7274
Onchocerca volvulus Neuropeptide F receptor homolog 0.0008 0.0032 0.0101
Entamoeba histolytica protein kinase, putative 0.0008 0.0026 0.0138
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0049 0.0156
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0006 0 0.0001
Onchocerca volvulus 0.0017 0.0129 0.0408
Schistosoma mansoni lamin 0.0008 0.0024 0.004
Schistosoma mansoni polycystin 1-related 0.002 0.0152 0.025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0025
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0049 0.0081
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0014 0.0091 0.0777
Plasmodium falciparum glutathione S-transferase 0.0027 0.0229 0.1913
Loa Loa (eye worm) hypothetical protein 0.0082 0.0822 0.3172
Schistosoma mansoni aldehyde dehydrogenase 0.01 0.1009 0.1661
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0181 0.1886 0.5977
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0129 0.0212
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0032 0.0053
Schistosoma mansoni glutathione-S-transferase 0.0027 0.0229 0.0378
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0008 0.0032 0.0053
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0031 0.0273 0.1448
Leishmania major elongation factor 1-gamma, putative 0.0006 0.0007 0.0062
Loa Loa (eye worm) AGC/AKT protein kinase 0.002 0.0157 0.0606
Trichomonas vaginalis AGC family protein kinase 0.002 0.0157 0.0498
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0032 0.0053

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) < 1 mM Irreversible inhibitory activity against alpha-chymotrypsin; No inhibition ChEMBL. No reference
Activity (binding) < 1 mM Irreversible inhibitory activity against alpha-chymotrypsin; No inhibition ChEMBL. No reference
K obs / 1 (binding) = 0.054 M-1 s-1 Compound was evaluated for inhibitory activity against alpha-chymotrypsin at a concentration of 6.0 x 10e-3 ChEMBL. No reference
K obs / 1 (binding) = 0.054 M-1 s-1 Compound was evaluated for inhibitory activity against alpha-chymotrypsin at a concentration of 6.0 x 10e-3 ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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