Detailed information for compound 14819

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 494.588 | Formula: C29H30N6O2
  • H donors: 1 H acceptors: 4 LogP: 4.63 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)C(OC)C
  • InChi: 1S/C29H30N6O2/c1-4-5-10-27-30-26-16-15-22(19(2)37-3)17-25(26)29(36)35(27)18-20-11-13-21(14-12-20)23-8-6-7-9-24(23)28-31-33-34-32-28/h6-9,11-17,19H,4-5,10,18H2,1-3H3,(H,31,32,33,34)
  • InChiKey: BWEPYZHEFBWAPC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Angiotensin II receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus E3 ubiquitin-protein ligase rpm-1 homolog Angiotensin II receptor   359 aa 352 aa 20.5 %
Schistosoma japonicum Rhodopsin, putative Angiotensin II receptor   359 aa 327 aa 24.2 %
Schistosoma mansoni opsin-like receptor Angiotensin II receptor   359 aa 299 aa 25.1 %
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Angiotensin II receptor   359 aa 303 aa 22.4 %
Echinococcus granulosus allatostatin A receptor Angiotensin II receptor   359 aa 348 aa 25.9 %
Brugia malayi ORL1-like opioid receptor Angiotensin II receptor   359 aa 314 aa 20.1 %
Onchocerca volvulus Angiotensin II receptor   359 aa 314 aa 25.8 %
Echinococcus multilocularis G-protein coupled receptor, putative Angiotensin II receptor   359 aa 308 aa 22.4 %
Echinococcus multilocularis allatostatin A receptor Angiotensin II receptor   359 aa 348 aa 25.9 %
Loa Loa (eye worm) hypothetical protein Angiotensin II receptor   359 aa 335 aa 23.3 %
Onchocerca volvulus Angiotensin II receptor   359 aa 312 aa 19.2 %
Echinococcus granulosus neuropeptide receptor Angiotensin II receptor   359 aa 316 aa 25.0 %
Loa Loa (eye worm) hypothetical protein Angiotensin II receptor   359 aa 330 aa 26.7 %
Schistosoma mansoni peptide (allatostatin)-like receptor Angiotensin II receptor   359 aa 314 aa 26.1 %
Echinococcus multilocularis neuropeptide receptor Angiotensin II receptor   359 aa 316 aa 25.3 %
Loa Loa (eye worm) neuropeptide F receptor Angiotensin II receptor   359 aa 356 aa 24.2 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Angiotensin II receptor   359 aa 336 aa 22.3 %
Onchocerca volvulus Angiotensin II receptor   359 aa 294 aa 23.8 %
Brugia malayi GnHR receptor homolog Angiotensin II receptor   359 aa 364 aa 20.9 %
Onchocerca volvulus Angiotensin II receptor   359 aa 303 aa 25.1 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Angiotensin II receptor   359 aa 334 aa 23.7 %
Echinococcus granulosus pyroglutamylated rfamide peptide receptor Angiotensin II receptor   359 aa 407 aa 19.4 %
Onchocerca volvulus Angiotensin II receptor   359 aa 386 aa 24.9 %
Schistosoma mansoni adenoreceptor Angiotensin II receptor   359 aa 329 aa 24.0 %
Onchocerca volvulus Angiotensin II receptor   359 aa 395 aa 23.0 %
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor Angiotensin II receptor   359 aa 406 aa 20.0 %
Brugia malayi putative neuropeptide receptor NPR1 Angiotensin II receptor   359 aa 295 aa 27.5 %
Echinococcus granulosus tm gpcr rhodopsin Angiotensin II receptor   359 aa 303 aa 22.4 %
Echinococcus granulosus thyrotropin releasing hormone receptor Angiotensin II receptor   359 aa 337 aa 24.0 %
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor Angiotensin II receptor   359 aa 346 aa 18.2 %
Echinococcus granulosus growth hormone secretagogue receptor type 1 Angiotensin II receptor   359 aa 351 aa 21.9 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Angiotensin II receptor   359 aa 311 aa 23.5 %
Echinococcus multilocularis growth hormone secretagogue receptor type 1 Angiotensin II receptor   359 aa 351 aa 21.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0213 0.0569 0.0804
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1239 0.3497 0.3497
Onchocerca volvulus 0.0883 0.2482 1
Trypanosoma brucei calpain-like protein, putative 0.0569 0.1586 0.4629
Trypanosoma cruzi cysteine peptidase, putative 0.1214 0.3426 0.7303
Trypanosoma cruzi major cysteine proteinase, putative 0.02 0.0533 0.1119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0477 0.1323 0.5313
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0062 0.0139 0.05
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Echinococcus multilocularis dro:myosuppressin receptor 0.0213 0.0569 0.0569
Brugia malayi cathepsin B-like cysteine proteinase 0.1657 0.4688 1
Entamoeba histolytica cysteine protease, putative 0.02 0.0533 0.2097
Plasmodium falciparum plasmepsin VIII, putative 0.0045 0.0091 0.0331
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.02 0.0533 0.0752
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0084 0.0202 0.1549
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0213 0.0569 0.0804
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0084
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0018 0.0066
Echinococcus multilocularis calpain 7 (C02 family) 0.0569 0.1586 0.1586
Plasmodium vivax serine-repeat antigen (SERA), putative 0.02 0.0533 0.2135
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0091 0.0124
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Brugia malayi aspartic protease BmAsp-1, identical 0.0045 0.0091 0.0187
Brugia malayi Matrixin family protein 0.0054 0.0116 0.024
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0084 0.0202 0.8864
Trichomonas vaginalis centrin, putative 0.0062 0.0139 0.0525
Brugia malayi calpain 5 0.0296 0.0806 0.1713
Loa Loa (eye worm) papain family cysteine protease containing protein 0.02 0.0533 0.1137
Brugia malayi Cathepsin L-like cysteine proteinase 0.0606 0.1692 0.3603
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0027 0.004 0.0078
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0213 0.0569 0.0804
Schistosoma mansoni mitochondrial solute carrier 0.0062 0.0139 0.0193
Onchocerca volvulus 0.0062 0.0139 0.0547
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0165 0.0333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Schistosoma mansoni thyroid hormone receptor 0.0134 0.0346 0.0487
Trichomonas vaginalis esterase, putative 0.0071 0.0165 0.063
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0204 0.0544 0.1585
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0204 0.0544 0.1585
Loa Loa (eye worm) calpain 5 0.0296 0.0806 0.172
Brugia malayi cathepsin F-like cysteine proteinase 0.0277 0.0753 0.16
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0084 0.0202 0.0588
Schistosoma mansoni ap endonuclease 0.0018 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0014
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.02 0.0533 0.2135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0569 0.1586 0.4615
Brugia malayi Papain family cysteine protease containing protein 0.0883 0.2482 0.529
Entamoeba histolytica hypothetical protein 0.02 0.0533 0.2097
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0084 0.0202 0.1549
Brugia malayi AKH receptor 0.0213 0.0569 0.1208
Entamoeba histolytica calmodulin, putative 0.0062 0.0139 0.05
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0092 0.0227 1
Onchocerca volvulus 0.0065 0.0147 0.058
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0091 0.0124
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0827 0.2322 0.4943
Loa Loa (eye worm) calpain 0.0569 0.1586 0.3384
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0084 0.0202 0.8864
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0084 0.0202 0.1549
Leishmania major hypothetical protein, conserved 0.0071 0.0165 0.0456
Plasmodium falciparum serine repeat antigen 1 0.02 0.0533 0.2117
Mycobacterium tuberculosis Conserved protein 0.0071 0.0165 0.1252
Trypanosoma brucei hypothetical protein, conserved 0.0062 0.0139 0.0404
Brugia malayi Tachykinin-like peptides receptor 99D 0.0213 0.0569 0.1208
Leishmania major cathepsin L-like protease 0.1214 0.3426 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0827 0.2322 0.6777
Mycobacterium leprae Probable lipase LipE 0.0071 0.0165 0.4789
Echinococcus multilocularis calpain 5 0.0569 0.1586 0.1586
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0084 0.0202 0.8864
Brugia malayi Cathepsin L-like precursor 0.0883 0.2482 0.529
Trypanosoma cruzi hypothetical protein, conserved 0.033 0.0904 0.1911
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0165 0.023
Brugia malayi Death domain containing protein 0.0014 0.0004 0.000000020611
Trichomonas vaginalis calmodulin, putative 0.0062 0.0139 0.0525
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0024 0.003 0.0106
Schistosoma mansoni cathepsin B (C01 family) 0.02 0.0533 0.0752
Leishmania major DNA polymerase eta, putative 0.0031 0.0052 0.0124
Trypanosoma brucei trypanothione reductase 0.0047 0.0097 0.0279
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0213 0.0569 0.0804
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0147 0.058
Echinococcus multilocularis calbindin 32 0.0063 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0195
Brugia malayi G-protein coupled receptor 0.0213 0.0569 0.1208
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Echinococcus multilocularis EF hand domain containing family member A2 0.0063 0.0143 0.0143
Brugia malayi follicle stimulating hormone receptor 0.0213 0.0569 0.1208
Trichomonas vaginalis calpain, putative 0.0274 0.0743 0.2969
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Schistosoma mansoni calpain-7 (C02 family) 0.0569 0.1586 0.225
Onchocerca volvulus Cathepsin F homolog 0.0883 0.2482 1
Trypanosoma cruzi conserved protein 0.0486 0.1349 0.2863
Echinococcus granulosus EF hand domain containing family member A2 0.0062 0.0139 0.0139
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0145 0.0201
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.02 0.0533 0.0752
Plasmodium vivax aspartyl protease, putative 0.0045 0.0091 0.0352
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0025
Loa Loa (eye worm) aspartyl protease 6 0.0045 0.0091 0.0195
Leishmania major hypothetical protein, conserved 0.0204 0.0544 0.1564
Leishmania major centrin, putative 0.0062 0.0139 0.038
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0091 0.0124
Loa Loa (eye worm) hypothetical protein 0.02 0.0533 0.1137
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.02 0.0533 0.2117
Loa Loa (eye worm) hypothetical protein 0.0228 0.0615 0.1311
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0009
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.02 0.0533 0.2117
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1657 0.4688 1
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0097 0.0186
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0038
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0062 0.0139 0.0546
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Echinococcus granulosus cytochrome P450 2K1 0.0084 0.0202 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.02 0.0533 0.2117
Onchocerca volvulus 0.0045 0.0091 0.0353
Brugia malayi Cathepsin L-like precursor 0.0277 0.0753 0.16
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0014
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0091 0.0124
Leishmania major protein kinase, putative 0.0062 0.0139 0.038
Loa Loa (eye worm) matrix metalloproteinase 0.0022 0.0027 0.0057
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0165 0.1252
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0204 0.0544 0.1585
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0165 0.0333
Echinococcus multilocularis cathepsin L 0.0477 0.1323 0.1323
Echinococcus granulosus rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0297 0.0811 0.2367
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0084 0.0202 0.1549
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0008
Plasmodium falciparum serine repeat antigen 3 0.02 0.0533 0.2117
Leishmania major small myristoylated protein-3, putative 0.0297 0.0811 0.2347
Trypanosoma brucei protein I/6 0.0062 0.0139 0.0404
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.0311 0.0663
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.02 0.0533 0.2135
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Echinococcus granulosus programmed cell death protein 0.007 0.0162 0.0162
Loa Loa (eye worm) glutathione reductase 0.0047 0.0097 0.0206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0226 0.0316
Onchocerca volvulus Cathepsin L homolog 0.0883 0.2482 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.02 0.0533 0.2117
Schistosoma mansoni DNA polymerase eta 0.0044 0.0089 0.0122
Trichomonas vaginalis calpain, putative 0.0274 0.0743 0.2969
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.02 0.0533 0.2117
Echinococcus multilocularis rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Schistosoma mansoni hypothetical protein 0.0213 0.0569 0.0804
Echinococcus granulosus hypothetical protein 0.0213 0.0569 0.0569
Schistosoma mansoni biogenic amine (5HT) receptor 0.0213 0.0569 0.0804
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0014
Echinococcus granulosus somatostatin receptor 0.0213 0.0569 0.0569
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0569 0.1586 0.3371
Plasmodium falciparum serine repeat antigen 5 0.02 0.0533 0.2117
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.02 0.0533 0.2117
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0062 0.0139 0.0525
Onchocerca volvulus 0.0015 0.0007 0.0011
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0452 0.1254 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0145 0.031
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0097 0.0097
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.065 0.1818 0.3866
Mycobacterium ulcerans hypothetical protein 0.0071 0.0165 0.7167
Leishmania major calmodulin, putative 0.0062 0.0139 0.038
Schistosoma mansoni neuronal calcium sensor 0.0062 0.0139 0.0193
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0086
Schistosoma mansoni neuropeptide receptor 0.0213 0.0569 0.0804
Toxoplasma gondii cathepsin B 0.065 0.1818 0.7321
Entamoeba histolytica cysteine proteinase, putative 0.0477 0.1323 0.5301
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0258 0.0699 0.2038
Brugia malayi G-protein coupled receptor 0.0213 0.0569 0.1208
Leishmania major cysteine peptidase A (CPA) 0.0883 0.2482 0.7236
Echinococcus multilocularis lamin 0.0027 0.0039 0.0039
Trypanosoma brucei Component of motile flagella 41 0.0062 0.0139 0.0404
Toxoplasma gondii calmodulin CAM1 0.0063 0.0143 0.0564
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0213 0.0569 0.0569
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Brugia malayi Thioredoxin reductase 0.0047 0.0097 0.0198
Trichomonas vaginalis centrin, putative 0.0062 0.0139 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Toxoplasma gondii calcium-dependent protein kinase 0.0063 0.0143 0.0564
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.019 0.0504 0.0504
Onchocerca volvulus 0.0608 0.1698 0.6837
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.046 0.1274 0.3717
Loa Loa (eye worm) matrixin family protein 0.0054 0.0116 0.0248
Brugia malayi Protein kinase domain containing protein 0.0024 0.003 0.0057
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.046 0.1274 0.2703
Entamoeba histolytica hypothetical protein, conserved 0.0063 0.0143 0.0517
Echinococcus multilocularis neuropeptides capa receptor 0.0213 0.0569 0.0569
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.02 0.0533 0.2117
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0827 0.2322 0.4943
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0139 0.0139
Toxoplasma gondii ABC1 family protein 0.0071 0.0165 0.0653
Trichomonas vaginalis calmodulin, putative 0.0062 0.0139 0.0525
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0226 0.0226
Schistosoma mansoni histamine h1 receptor 0.0213 0.0569 0.0804
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0267 0.2071
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0016 0.0016
Onchocerca volvulus 0.0213 0.0569 0.2283
Plasmodium falciparum plasmepsin X 0.0045 0.0091 0.0331
Leishmania major hypothetical protein, conserved 0.0204 0.0544 0.1564
Echinococcus multilocularis sex peptide receptor 0.0213 0.0569 0.0569
Schistosoma mansoni hypothetical protein 0.0051 0.0109 0.015
Plasmodium vivax glutathione reductase, putative 0.0047 0.0097 0.0374
Brugia malayi CXXC zinc finger family protein 0.0028 0.0044 0.0085
Onchocerca volvulus 0.0015 0.0007 0.0011
Echinococcus granulosus serotonin receptor 0.0213 0.0569 0.0569
Onchocerca volvulus 0.0015 0.0007 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0139 0.0193
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0004 0.0008
Loa Loa (eye worm) beta-lactamase 0.0071 0.0165 0.0353
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0165 0.048
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Schistosoma mansoni neuropeptide receptor 0.0213 0.0569 0.0804
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) TYRA-2 protein 0.0213 0.0569 0.1215
Echinococcus granulosus calmodulin 0.0062 0.0139 0.0139
Entamoeba histolytica calmodulin, putative 0.0062 0.0139 0.05
Schistosoma mansoni calpain (C02 family) 0.0569 0.1586 0.225
Trichomonas vaginalis calcium binding proteins, putative 0.0062 0.0139 0.0525
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.1987 0.579
Onchocerca volvulus 0.0027 0.0039 0.0143
Echinococcus granulosus tm gpcr rhodopsin 0.0213 0.0569 0.0569
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0011 0.001
Plasmodium vivax plasmepsin V, putative 0.0045 0.0091 0.0352
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.02 0.0533 0.2117
Onchocerca volvulus 0.0065 0.0147 0.058
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Brugia malayi calpain family protein 1 0.1177 0.3321 0.7082
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0052 0.0196
Plasmodium falciparum plasmepsin V 0.0045 0.0091 0.0331
Entamoeba histolytica papain family cysteine protease domain containing protein 0.02 0.0533 0.2097
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.02 0.0533 0.0752
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0147 0.058
Trypanosoma cruzi centrin-3 0.007 0.0162 0.0326
Onchocerca volvulus 0.0045 0.0091 0.0353
Onchocerca volvulus 0.0015 0.0007 0.0011
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0213 0.0569 0.0804
Onchocerca volvulus 0.0883 0.2482 1
Echinococcus multilocularis g protein coupled receptor 0.0213 0.0569 0.0569
Leishmania major small myristoylated protein-1 0.0351 0.0965 0.2796
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0016 0.0027
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0258 0.0699 0.2038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0477 0.1324 0.281
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0015 0.0007 0.0013
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0062 0.0139 0.0193
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0081 0.0194 0.0194
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1177 0.3321 0.4717
Trypanosoma brucei mitochondrial calcium uptake 1 0.0062 0.0139 0.0404
Onchocerca volvulus 0.0883 0.2482 1
Trichomonas vaginalis calcium binding protein, putative 0.0062 0.0139 0.0525
Schistosoma mansoni cathepsin F (C01 family) 0.0883 0.2482 0.3523
Echinococcus granulosus g protein coupled receptor 0.0213 0.0569 0.0569
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0165 0.1252
Leishmania major cytochrome p450-like protein 0.0092 0.0227 0.0636
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Echinococcus multilocularis rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Leishmania major cathepsin L-like protease 0.0883 0.2482 0.7236
Schistosoma mansoni cathepsin C 0.02 0.0533 0.0752
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Brugia malayi Cathepsin L-like precursor 0.0606 0.1692 0.3603
Giardia lamblia Hypothetical protein 0.02 0.0533 0.2894
Brugia malayi hypothetical protein 0.0025 0.0034 0.0065
Brugia malayi hypothetical protein 0.0228 0.0615 0.1304
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Trypanosoma cruzi cytochrome P450, putative 0.0092 0.0227 0.0465
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0213 0.0569 0.0569
Echinococcus granulosus rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Entamoeba histolytica grainin, putative 0.0063 0.0143 0.0517
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0014
Brugia malayi Hemopexin family protein 0.0031 0.0053 0.0105
Brugia malayi neuropeptide F receptor 0.0213 0.0569 0.1208
Loa Loa (eye worm) neuropeptide F receptor 0.0213 0.0569 0.1215
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0477 0.1324 0.281
Echinococcus granulosus cathepsin b 0.1657 0.4688 0.4688
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Schistosoma mansoni cytochrome P450 0.0084 0.0202 0.0282
Toxoplasma gondii cytochrome p450 superfamily protein 0.0084 0.0202 0.0802
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0084 0.0202 0.8864
Echinococcus granulosus neuronal calcium sensor 0.0062 0.0139 0.0139
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0022 0.0027 0.0032
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0883 0.2482 0.5294
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0016 0.0014
Leishmania major kinesin, putative 0.0296 0.0806 0.2332
Loa Loa (eye worm) G-protein coupled receptor 0.0213 0.0569 0.1215
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.02 0.0533 0.2117
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.065 0.1818 0.5293
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0007 0.0013
Brugia malayi Cathepsin L-like precursor 0.0883 0.2482 0.529
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0018 0.003
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0213 0.0569 0.2283
Schistosoma mansoni reticulocalbin 0.0062 0.0139 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.02 0.0533 0.2117
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0097 0.0097
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0165 0.023
Echinococcus granulosus rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Loa Loa (eye worm) calmodulin-like protein 0.0062 0.0139 0.0297
Echinococcus multilocularis g protein coupled receptor 0.0213 0.0569 0.0569
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0277 0.0753 0.1607
Trypanosoma cruzi cysteine peptidase, putative 0.0883 0.2482 0.5285
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0147 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma brucei hypothetical protein 0.0532 0.1479 0.4316
Plasmodium falciparum serine repeat antigen 9 0.02 0.0533 0.2117
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Echinococcus granulosus intermediate filament protein 0.0027 0.0039 0.0039
Giardia lamblia Cysteine protease 0.02 0.0533 0.2894
Entamoeba histolytica cysteine proteinase, putative 0.0883 0.2482 1
Leishmania major calpain family cysteine protease-like protein 0.0477 0.1324 0.3847
Schistosoma mansoni lamin 0.0027 0.0039 0.005
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.019 0.0504 0.2021
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1239 0.3497 0.4967
Onchocerca volvulus 0.0071 0.0165 0.0652
Onchocerca volvulus 0.0015 0.0007 0.0011
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0016 0.0026
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.02 0.0533 0.2117
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0768 0.2153 0.6275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0084 0.0202 0.1549
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0045 0.0091 0.0195
Giardia lamblia Cathepsin B precursor 0.02 0.0533 0.2894
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0084 0.0202 0.8864
Toxoplasma gondii EF hand domain-containing protein 0.0062 0.0139 0.0548
Entamoeba histolytica cysteine protease, putative 0.02 0.0533 0.2097
Echinococcus granulosus neuropeptides capa receptor 0.0213 0.0569 0.0569
Brugia malayi G protein-coupled receptor 0.0213 0.0569 0.1208
Plasmodium vivax serine-repeat antigen (SERA) 0.02 0.0533 0.2135
Plasmodium falciparum plasmepsin IV 0.019 0.0504 0.2001
Echinococcus multilocularis neurocalcin 0.0062 0.0139 0.0139
Onchocerca volvulus 0.0063 0.0143 0.0563
Trypanosoma brucei cysteine peptidase, putative 0.0477 0.1324 0.3863
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0537 0.1494 0.3174
Loa Loa (eye worm) hypothetical protein 0.1657 0.4688 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0016 0.0014
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0267 0.2071
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0057
Leishmania major cathepsin L-like protease 0.0883 0.2482 0.7236
Brugia malayi intermediate filament protein 0.0027 0.0039 0.0076
Schistosoma mansoni neuronal calcium sensor 0.0062 0.0139 0.0193
Loa Loa (eye worm) fibroinase 0.0883 0.2482 0.5294
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0062 0.0139 0.05
Echinococcus granulosus alpha 1A adrenergic receptor 0.0213 0.0569 0.0569
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0213 0.0569 0.0804
Onchocerca volvulus 0.0015 0.0007 0.0011
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0027 0.004 0.0249
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0213 0.0569 0.1208
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0827 0.2322 0.4943
Loa Loa (eye worm) hypothetical protein 0.02 0.0533 0.1137
Echinococcus multilocularis calpain A 0.1241 0.3501 0.3501
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0018 0.0049
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0084 0.0202 0.0412
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Schistosoma mansoni hypothetical protein 0.0167 0.0441 0.0621
Trypanosoma cruzi calmodulin, putative 0.0062 0.0139 0.0277
Onchocerca volvulus Dual oxidase homolog 0.0065 0.0147 0.058
Brugia malayi Cytochrome P450 family protein 0.0092 0.0227 0.0476
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.02 0.0533 0.2117
Trypanosoma cruzi I/6 autoantigen, putative 0.0062 0.0139 0.0277
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0213 0.0569 0.0569
Plasmodium vivax SET domain protein, putative 0.0062 0.0139 0.0547
Entamoeba histolytica calcium-binding protein, putative 0.0062 0.0139 0.05
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0016 0.0035
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0062 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0904 0.2541 0.542
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Toxoplasma gondii centrin, putative 0.0062 0.0139 0.0548
Schistosoma mansoni hypothetical protein 0.0213 0.0569 0.0804
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0018 0.0049
Trypanosoma brucei conserved protein 0.0212 0.0569 0.1658
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.046 0.1274 0.3701
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0018 0.0018
Echinococcus multilocularis Ankyrin 0.0014 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0139 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0258 0.0699 0.2038
Loa Loa (eye worm) aspartic protease BmAsp-2 0.019 0.0504 0.1076
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0258 0.0699 0.1474
Loa Loa (eye worm) papain family cysteine protease containing protein 0.02 0.0533 0.1137
Mycobacterium tuberculosis Conserved protein 0.0071 0.0165 0.1252
Schistosoma mansoni amine GPCR 0.0213 0.0569 0.0804
Trypanosoma brucei hypothetical protein, conserved 0.033 0.0904 0.2636
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0034 0.0101
Echinococcus multilocularis cathepsin L cysteine protease 0.0883 0.2482 0.2482
Entamoeba histolytica cysteine protease, putative 0.02 0.0533 0.2097
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0064 0.0085
Echinococcus multilocularis lamin dm0 0.0027 0.0039 0.0039
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0016 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0213 0.0569 0.1215
Entamoeba histolytica cysteine proteinase, putative 0.0477 0.1323 0.5301
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.0194
Trypanosoma brucei kinesin, putative 0.0296 0.0806 0.2351
Echinococcus granulosus rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Schistosoma mansoni neuronal calcium sensor 0.0062 0.0139 0.0193
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0018 0.0066
Loa Loa (eye worm) RNA binding protein 0.0064 0.0145 0.031
Onchocerca volvulus 0.0015 0.0007 0.0011
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0062 0.0139 0.0277
Echinococcus multilocularis calmodulin 0.0062 0.0139 0.0139
Echinococcus granulosus sex peptide receptor 0.0213 0.0569 0.0569
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0544 0.1142
Brugia malayi Blistered cuticle protein 3 0.0065 0.0147 0.0307
Echinococcus multilocularis G-protein coupled receptor, putative 0.0213 0.0569 0.0569
Brugia malayi Serotonin receptor 0.0213 0.0569 0.1208
Loa Loa (eye worm) hypothetical protein 0.0274 0.0743 0.1586
Loa Loa (eye worm) hypothetical protein 0.0062 0.0139 0.0297
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0451 0.1249 0.1771
Brugia malayi Papain family cysteine protease containing protein 0.0477 0.1323 0.2816
Loa Loa (eye worm) hypothetical protein 0.019 0.0504 0.1076
Onchocerca volvulus 0.0028 0.0044 0.0161
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0023 0.0056
Plasmodium falciparum glutathione reductase 0.0047 0.0097 0.0352
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0213 0.0569 0.1208
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0213 0.0569 0.0569
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0016 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0018 0.0033
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0131 0.0131
Giardia lamblia Dipeptidyl-peptidase I precursor 0.02 0.0533 0.2894
Leishmania major calcineurin B subunit, putative 0.0062 0.0139 0.038
Brugia malayi programmed cell death protein 6 0.0062 0.0139 0.0289
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0213 0.0569 0.1215
Leishmania major phospholipase c-like protein 0.0062 0.0139 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.02 0.0533 0.2117
Toxoplasma gondii preprocathepsin c precursor, putative 0.02 0.0533 0.2136
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.02 0.0533 0.0752
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0213 0.0569 0.0569
Echinococcus granulosus bloom syndrome protein 0.0021 0.0023 0.0023
Plasmodium falciparum calpain 0.0274 0.0743 0.2969
Plasmodium vivax calpain, putative 0.0569 0.1586 0.6386
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0301 0.2344
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.0194
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0044 0.0093
Plasmodium vivax aspartyl protease, putative 0.0045 0.0091 0.0352
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0007 0.0013
Echinococcus multilocularis programmed cell death protein 0.007 0.0162 0.0162
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0619 0.1727 0.5028
Entamoeba histolytica calpain large subunit domain III containing protein 0.0296 0.0806 0.3205
Onchocerca volvulus 0.0213 0.0569 0.2283
Brugia malayi cathepsin F-like cysteine proteinase 0.02 0.0533 0.1129
Onchocerca volvulus 0.0047 0.0096 0.0373
Echinococcus granulosus centrin 2 0.0062 0.0139 0.0139
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0213 0.0569 0.0569
Trichomonas vaginalis conserved hypothetical protein 0.0274 0.0743 0.2969
Brugia malayi calpain D 0.0274 0.0743 0.1579
Schistosoma mansoni neuropeptide receptor 0.0213 0.0569 0.0804
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0139 0.0193
Schistosoma mansoni neuronal calcium sensor 0.0062 0.0139 0.0193
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0204 0.0544 0.1564
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0743 0.2969
Schistosoma mansoni biogenic amine receptor 0.0213 0.0569 0.0804
Brugia malayi beta-lactamase family protein 0.0071 0.0165 0.0345
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0007 0.0013
Giardia lamblia Cathepsin L-like protease 0.02 0.0533 0.2894
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0062 0.0139 0.0277
Schistosoma mansoni survival motor neuron protein 0.0047 0.0096 0.0131
Leishmania major cathepsin L-like protease 0.1214 0.3426 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0134 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0026 0.0038 0.0081
Onchocerca volvulus 0.0213 0.0569 0.2283
Echinococcus multilocularis neuropeptide Y receptor 0.0213 0.0569 0.0569
Plasmodium vivax unspecified product 0.0477 0.1323 0.5323
Schistosoma mansoni calmodulin 0.0062 0.0139 0.0193
Echinococcus multilocularis geminin 0.0167 0.0441 0.0441
Trypanosoma brucei antigen, putative 0.0569 0.1586 0.4629
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.02 0.0533 0.2894
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0213 0.0569 0.0804
Trichomonas vaginalis conserved hypothetical protein 0.02 0.0533 0.2117
Plasmodium falciparum cysteine repeat modular protein 1 0.0024 0.003 0.0084
Trichomonas vaginalis calcium binding protein, putative 0.0062 0.0139 0.0525
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.02 0.0533 0.2135
Echinococcus granulosus tm gpcr rhodopsin 0.0213 0.0569 0.0569
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.019 0.0504 0.0712
Echinococcus granulosus calbindin 32 0.0063 0.0143 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0477 0.1323 0.386
Plasmodium falciparum cysteine proteinase falcipain 3 0.0883 0.2482 1
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0145 0.0302
Trypanosoma cruzi small myristoylated protein 1-2 0.0351 0.0965 0.2042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0213 0.0569 0.0804
Echinococcus granulosus cathepsin L cysteine protease 0.0477 0.1323 0.1323
Brugia malayi hypothetical protein 0.012 0.0306 0.0646
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0213 0.0569 0.0569
Trypanosoma cruzi calmodulin, putative 0.0062 0.0139 0.0277
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0544 0.1142
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0084 0.0202 0.8864
Entamoeba histolytica cysteine protease, putative 0.02 0.0533 0.2097
Onchocerca volvulus 0.0883 0.2482 1
Echinococcus multilocularis EF hand domain containing family member A2 0.0062 0.0139 0.0139
Schistosoma mansoni peroxidasin 0.0065 0.0147 0.0204
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0477 0.1324 0.3847
Toxoplasma gondii hypothetical protein 0.0015 0.0007 0.0013
Toxoplasma gondii microneme protein MIC17B 0.0015 0.0007 0.0013
Giardia lamblia Cathepsin L precursor 0.02 0.0533 0.2894
Trypanosoma cruzi cruzipain precursor, putative 0.0277 0.0753 0.159
Toxoplasma gondii subtilisin SUB12 0.0015 0.0007 0.0013
Echinococcus granulosus g protein coupled receptor 0.0213 0.0569 0.0569
Brugia malayi Eukaryotic aspartyl protease family protein 0.0045 0.0091 0.0187
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0084 0.0202 0.1549
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0587 0.1637 0.348
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.02 0.0533 0.2117
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0004 0.0009
Schistosoma mansoni cathepsin s 0.0277 0.0753 0.1066
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0062 0.0139 0.0525
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0139 0.0139
Entamoeba histolytica cysteine proteinase, putative 0.0606 0.1692 0.6796
Schistosoma mansoni cathepsin F (C01 family) 0.0883 0.2482 0.3523
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.02 0.0533 0.0752
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0213 0.0569 0.0569
Echinococcus multilocularis tissue type plasminogen activator 0.0024 0.003 0.003
Trypanosoma brucei centrin, putative 0.0062 0.0139 0.0404
Echinococcus multilocularis g protein coupled receptor 0.0213 0.0569 0.0569
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.0615 0.0615
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Brugia malayi G protein-coupled receptor F59B2.13 0.0213 0.0569 0.1208
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0768 0.2153 0.6275
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0016 0.0016
Brugia malayi Dopamine receptor protein 2 0.0213 0.0569 0.1208
Giardia lamblia Cathepsin L precursor 0.02 0.0533 0.2894
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0532 0.1479 0.4316
Echinococcus granulosus dna polymerase eta 0.0044 0.0089 0.0089
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0009
Entamoeba histolytica grainin 2 0.007 0.0162 0.0593
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Loa Loa (eye worm) hypothetical protein 0.0277 0.0753 0.1607
Plasmodium falciparum serine repeat antigen 8 0.02 0.0533 0.2117
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0204 0.0544 0.1585
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0084 0.0202 0.0412
Schistosoma mansoni hypothetical protein 0.0062 0.0139 0.0193
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0165 0.063
Echinococcus granulosus cathepsin b 0.1657 0.4688 0.4688
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.1987 0.579
Trichomonas vaginalis calcineurin B subunit, putative 0.0062 0.0139 0.0525
Echinococcus multilocularis 0.0084 0.0202 0.0202
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0213 0.0569 0.0569
Brugia malayi fibroinase precursor 0.02 0.0533 0.1129
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0009 0.0012
Toxoplasma gondii EFHC1, putative 0.0062 0.0139 0.0548
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0084 0.0202 0.8864
Trichomonas vaginalis calpain, putative 0.0274 0.0743 0.2969
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.248 0.7036 1
Trypanosoma cruzi unspecified product 0.0351 0.0965 0.2042
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) programmed cell death protein 6 0.0063 0.0143 0.0306
Onchocerca volvulus 0.0213 0.0569 0.2283
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0606 0.1692 0.6804
Toxoplasma gondii cathepsin CPC2 0.02 0.0533 0.2136
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0213 0.0569 0.0804
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0064 0.0064
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0477 0.1324 0.281
Loa Loa (eye worm) neuropeptide F receptor 0.0213 0.0569 0.1215
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0743 0.2969
Toxoplasma gondii troponin c, isotype gamma, putative 0.0062 0.0139 0.0548
Echinococcus granulosus tm gpcr rhodopsin 0.0213 0.0569 0.0569
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0165 0.0165
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0084 0.0202 0.1549
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0062 0.0139 0.0297
Loa Loa (eye worm) CYP4Cod1 0.0092 0.0227 0.0484
Plasmodium vivax serine-repeat antigen (SERA) 0.02 0.0533 0.2135
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1239 0.3497 0.3497
Echinococcus multilocularis neuropeptide s receptor 0.0213 0.0569 0.0569
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0827 0.2322 0.6769
Brugia malayi cathepsin Z-like cysteine proteinase 0.02 0.0533 0.1129
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0226 0.0482
Onchocerca volvulus Peroxidase homolog 0.0065 0.0147 0.058
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0267 0.2071
Brugia malayi calpain family protein 1 0.1177 0.3321 0.7082
Brugia malayi calpain 7 0.0569 0.1586 0.3379
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0018 0.0033
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0204 0.0544 0.1585
Giardia lamblia Encystation-specific protease 0.02 0.0533 0.2894
Loa Loa (eye worm) hypothetical protein 0.0883 0.2482 0.5294
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0226 0.0316
Echinococcus multilocularis calpain family protein 1, d 0.0882 0.2478 0.2478
Echinococcus granulosus peptide allatostatin:somatostatin 0.0213 0.0569 0.0569
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0007 0.0014
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.0194
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Leishmania major hypothetical protein, conserved 0.0062 0.0139 0.038
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Trypanosoma brucei calpain, putative 0.0532 0.1479 0.4316
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0145 0.031
Onchocerca volvulus 0.0065 0.0147 0.058
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.02 0.0533 0.2135
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0139 0.0549
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0165 0.063
Onchocerca volvulus 0.0213 0.0569 0.2283
Brugia malayi Calmodulin-like protein 0.0062 0.0139 0.0289
Schistosoma mansoni amine GPCR 0.0213 0.0569 0.0804
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Trichomonas vaginalis calmodulin, putative 0.0062 0.0139 0.0525
Leishmania major hypothetical protein, conserved 0.0025 0.0034 0.0073
Brugia malayi beta-lactamase family protein 0.0071 0.0165 0.0345
Entamoeba histolytica cysteine proteinase 1, putative 0.0477 0.1323 0.5301
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0039 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0034 0.0101
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0008
Onchocerca volvulus 0.0486 0.1349 0.543
Brugia malayi Papain family cysteine protease containing protein 0.02 0.0533 0.1129
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0569 0.1586 0.3371
Leishmania major hypothetical protein, unknown function 0.0274 0.0743 0.2148
Schistosoma mansoni cathepsin F (C01 family) 0.0606 0.1692 0.24
Trypanosoma brucei Calpain-like protein 2 0.0601 0.1677 0.4895
Giardia lamblia Cathepsin B precursor 0.02 0.0533 0.2894
Brugia malayi hypothetical protein 0.0045 0.0091 0.0187
Onchocerca volvulus 0.0213 0.0569 0.2283
Leishmania major calpain protease-like protein 0.0274 0.0743 0.2148
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0097 0.0206
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0297 0.0811 0.1714
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0165 0.063
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.02 0.0533 0.1137
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0165 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.02 0.0533 0.2117
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0213 0.0569 0.0569
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1657 0.4688 0.666
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0477 0.1324 0.281
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0301 0.2344
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0811 0.2275 0.6639
Plasmodium vivax aspartyl protease, putative 0.0045 0.0091 0.0352
Loa Loa (eye worm) hypothetical protein 0.0044 0.0089 0.0191
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0768 0.2153 0.6275
Brugia malayi sulfakinin receptor protein 0.0213 0.0569 0.1208
Toxoplasma gondii cathepsin CPL 0.0883 0.2482 1
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0084 0.0202 0.1549
Onchocerca volvulus Cathepsin L homolog 0.0883 0.2482 1
Leishmania major hypothetical protein, conserved 0.033 0.0904 0.2617
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0544 0.1142
Onchocerca volvulus 0.0213 0.0569 0.2283
Brugia malayi Dopamine receptor 0.0213 0.0569 0.1208
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0204 0.0544 0.1142
Onchocerca volvulus 0.0213 0.0569 0.2283
Plasmodium vivax unspecified product 0.0277 0.0753 0.3025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1657 0.4688 0.666
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0274 0.0743 0.2168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.02 0.0533 0.2117
Onchocerca volvulus Matrilysin homolog 0.0022 0.0027 0.0092
Trypanosoma brucei cysteine peptidase C (CPC) 0.065 0.1818 0.5305
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Echinococcus granulosus g-protein coupled receptor 0.0213 0.0569 0.0569
Leishmania major cathepsin L-like protease 0.0883 0.2482 0.7236
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0084 0.0202 0.8864
Echinococcus multilocularis programmed cell death protein 0.007 0.0162 0.0162
Toxoplasma gondii aspartyl protease ASP3 0.0045 0.0091 0.0354
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.02 0.0533 0.0752
Giardia lamblia Cathepsin B precursor 0.02 0.0533 0.2894
Brugia malayi Papain family cysteine protease containing protein 0.0477 0.1323 0.2816
Brugia malayi putative neuropeptide receptor NPR1 0.0213 0.0569 0.1208
Onchocerca volvulus 0.0213 0.0569 0.2283
Brugia malayi RNA binding protein 0.0064 0.0145 0.0302
Echinococcus granulosus EF hand domain containing family member A2 0.0063 0.0143 0.0143
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0267 0.8699
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0009
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0213 0.0569 0.1208
Entamoeba histolytica cysteine proteinase 2 0.0477 0.1323 0.5301
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0477 0.1324 0.281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0213 0.0569 0.0804
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.1541 0.3274
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0062 0.0139 0.0139
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.046 0.1274 0.3701
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Echinococcus multilocularis cysteine protease 0.0883 0.2482 0.2482
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0084 0.0202 0.0412
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0883 0.2482 0.2482
Entamoeba histolytica calcium binding family protein 0.0062 0.0139 0.05
Onchocerca volvulus 0.0071 0.0165 0.0652
Loa Loa (eye worm) hypothetical protein 0.0071 0.0165 0.0353
Brugia malayi Pre-SET motif family protein 0.0427 0.1181 0.2513
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Leishmania major cytochrome p450-like protein 0.0084 0.0202 0.0564
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0097 0.0374
Loa Loa (eye worm) hypothetical protein 0.02 0.0533 0.1137
Loa Loa (eye worm) hypothetical protein 0.0606 0.1692 0.3609
Onchocerca volvulus Cathepsin L homolog 0.02 0.0533 0.2135
Toxoplasma gondii centrin 0.0062 0.0139 0.0548
Leishmania major calmodulin, putative 0.0062 0.0139 0.038
Onchocerca volvulus 0.0071 0.0165 0.0652
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0743 0.2969
Echinococcus multilocularis neuropeptide Y receptor 0.0213 0.0569 0.0569
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Schistosoma mansoni hypothetical protein 0.0062 0.0139 0.0193
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0213 0.0569 0.0569
Plasmodium falciparum plasmepsin VII 0.0045 0.0091 0.0331
Echinococcus granulosus cathepsin L 0.0477 0.1323 0.1323
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0097 0.07
Echinococcus granulosus Ankyrin 0.0014 0.0004 0.0004
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.02 0.0533 0.2135
Entamoeba histolytica papain family cysteine protease domain containing protein 0.02 0.0533 0.2097
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0007 0.0014
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0277 0.0753 0.16
Trichomonas vaginalis calmodulin, putative 0.0062 0.0139 0.0525
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0009 0.0022
Trichomonas vaginalis calcium binding protein, putative 0.0062 0.0139 0.0525
Trypanosoma cruzi cysteine peptidase, putative 0.0277 0.0753 0.159
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0084 0.0202 0.0564
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0811 0.2275 0.663
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Schistosoma mansoni cpg binding protein 0.003 0.0048 0.0063
Echinococcus granulosus tar DNA binding protein 0.0064 0.0145 0.0145
Schistosoma mansoni adenoreceptor 0.0213 0.0569 0.0804
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Brugia malayi hypothetical protein 0.0065 0.0147 0.0307
Brugia malayi Kringle domain containing protein 0.0024 0.003 0.0057
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0532 0.1479 0.4302
Loa Loa (eye worm) hypothetical protein 0.0882 0.2478 0.5287
Echinococcus granulosus calpain A 0.1241 0.3501 0.3501
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.019 0.0504 0.2001
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0213 0.0569 0.0569
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0009 0.0025
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Trypanosoma cruzi cruzipain precursor, putative 0.1214 0.3426 0.7303
Echinococcus multilocularis serotonin receptor 0.0213 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) cathepsin B 0.065 0.1818 0.3878
Schistosoma mansoni thyroid hormone receptor 0.0134 0.0346 0.0487
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0213 0.0569 0.0804
Schistosoma mansoni hypothetical protein 0.0167 0.0441 0.0621
Echinococcus granulosus rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Onchocerca volvulus 0.0015 0.0007 0.0011
Echinococcus granulosus 7tm_1 domain containing protein 0.0213 0.0569 0.0569
Loa Loa (eye worm) TK/ROR protein kinase 0.0024 0.003 0.0065
Echinococcus multilocularis musashi 0.0027 0.0039 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Leishmania major small myristoylated protein-2 0.064 0.1788 0.5205
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0004 0.0004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0064 0.0064
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0084 0.0202 0.1549
Mycobacterium ulcerans beta-lactamase 0.0071 0.0165 0.7167
Leishmania major cytochrome p450-like protein 0.0084 0.0202 0.0564
Echinococcus granulosus geminin 0.0167 0.0441 0.0441
Onchocerca volvulus 0.0062 0.0139 0.0546
Trypanosoma cruzi cysteine protease, putative 0.0477 0.1323 0.2808
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0063 0.0143 0.0286
Schistosoma mansoni growth hormone secretagogue receptor 0.0213 0.0569 0.0804
Brugia malayi Matrixin family protein 0.0022 0.0027 0.0049
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0165 0.0345
Toxoplasma gondii hypothetical protein 0.0015 0.0007 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Giardia lamblia Cysteine protease 0.02 0.0533 0.2894
Echinococcus granulosus fmrfamide receptor 0.0213 0.0569 0.0569
Schistosoma mansoni reticulocalbin 0.0063 0.0143 0.0198
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0213 0.0569 0.0804
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0226 0.0226
Schistosoma mansoni neuropeptide F-like receptor 0.0213 0.0569 0.0804
Leishmania major hypothetical protein, conserved 0.0204 0.0544 0.1564
Brugia malayi hypothetical protein 0.0035 0.0064 0.0128
Schistosoma mansoni hypothetical protein 0.0124 0.0318 0.0447
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0018 0.0038
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0084 0.0202 0.8864
Echinococcus granulosus cathepsin L cysteine proteinase 0.0883 0.2482 0.2482
Giardia lamblia Cysteine protease 0.02 0.0533 0.2894
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0301 0.2344
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0009 0.0024
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0062 0.0139 0.0277
Echinococcus granulosus rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Onchocerca volvulus Neuropeptide F receptor homolog 0.0213 0.0569 0.2283
Trypanosoma brucei centrin-3 0.007 0.0162 0.0471
Onchocerca volvulus Matrix metalloproteinase homolog 0.0049 0.0104 0.0403
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0213 0.0569 0.0569
Echinococcus granulosus dna polymerase kappa 0.0019 0.0018 0.0018
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0477 0.1323 0.1876
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Leishmania major cathepsin L-like protease 0.0883 0.2482 0.7236
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0084 0.0202 0.1549
Leishmania major hypothetical protein, conserved 0.0204 0.0544 0.1564
Toxoplasma gondii microneme protein MIC17A 0.0015 0.0007 0.0013
Onchocerca volvulus 0.0213 0.0569 0.2283
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0007 0.0014
Onchocerca volvulus 0.0015 0.0007 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.02 0.0533 0.2117
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0883 0.2482 0.5294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0213 0.0569 0.0804
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0147 0.0307
Schistosoma mansoni hypothetical protein 0.0274 0.0743 0.1052
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Echinococcus granulosus cysteine protease 0.0477 0.1323 0.1323
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0143 0.0562
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0084 0.0202 0.1549
Onchocerca volvulus 0.0031 0.0053 0.0199
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0165 0.1252
Schistosoma mansoni calpain C (C02 family) 0.0569 0.1586 0.225
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Toxoplasma gondii exonuclease III APE 0.0018 0.0016 0.005
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0062 0.0139 0.0404
Echinococcus granulosus calpain 0.0569 0.1586 0.1586
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.1177 0.3321 0.7085
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0811 0.2275 0.4842
Loa Loa (eye worm) hypothetical protein 0.0277 0.0753 0.1607
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0213 0.0569 0.1208
Echinococcus multilocularis cysteine protease 0.0883 0.2482 0.2482
Schistosoma mansoni myosin xvIII 0.0213 0.0569 0.0804
Entamoeba histolytica cysteine proteinase, putative 0.0883 0.2482 1
Schistosoma mansoni amine GPCR 0.0213 0.0569 0.0804
Echinococcus granulosus calpain 7 C02 family 0.0569 0.1586 0.1586
Loa Loa (eye worm) hypothetical protein 0.02 0.0533 0.1137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Echinococcus multilocularis cathepsin b 0.1657 0.4688 0.4688
Schistosoma mansoni calmodulin related calcium binding protein 0.0062 0.0139 0.0193
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0007 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Onchocerca volvulus 0.0606 0.1692 0.6811
Leishmania major programmed cell death 6 protein-like protein 0.0062 0.0139 0.038
Brugia malayi neuropeptide F receptor 0.0213 0.0569 0.1208
Trypanosoma cruzi caltractin, putative 0.0062 0.0139 0.0277
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Schistosoma mansoni ef hand domain family member A2 0.0062 0.0139 0.0193
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Schistosoma mansoni peroxidasin 0.0065 0.0147 0.0204
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0018 0.0018
Echinococcus multilocularis calumenin 0.0063 0.0143 0.0143
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0039 0.0084
Onchocerca volvulus 0.0883 0.2482 1
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0318 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.02 0.0533 0.2117
Schistosoma mansoni memapsin-2 (A01 family) 0.0045 0.0091 0.0124
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0213 0.0569 0.0804
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0165 0.063
Echinococcus multilocularis calpain 0.0569 0.1586 0.1586
Giardia lamblia Cathepsin L-like protease 0.02 0.0533 0.2894
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0883 0.2482 1
Mycobacterium leprae Conserved hypothetical protein 0.0084 0.0202 0.6204
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.014 0.0194
Plasmodium falciparum thioredoxin reductase 0.0047 0.0097 0.0352
Echinococcus granulosus cpg binding protein 0.003 0.0048 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Giardia lamblia Dipeptidyl-peptidase I precursor 0.02 0.0533 0.2894
Brugia malayi cathepsin L precursor 0.02 0.0533 0.1129
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0071 0.0165 0.0353
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.0311 0.0663
Brugia malayi Cytochrome P450 family protein 0.0084 0.0202 0.0423
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.02 0.0533 0.2135
Toxoplasma gondii microneme protein MIC17C 0.0015 0.0007 0.0013
Schistosoma mansoni centrin-related 0.0062 0.0139 0.0193
Schistosoma mansoni amine GPCR 0.0213 0.0569 0.0804
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Loa Loa (eye worm) hypothetical protein 0.0313 0.0857 0.1828
Giardia lamblia Hypothetical protein 0.02 0.0533 0.2894
Schistosoma mansoni opsin-like receptor 0.0213 0.0569 0.0804
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Echinococcus granulosus neuropeptide FF receptor 2 0.0213 0.0569 0.0569
Brugia malayi larval opioid receptor 0.0213 0.0569 0.1208
Trypanosoma brucei unspecified product 0.0019 0.0018 0.0049
Echinococcus granulosus tissue type plasminogen activator 0.0024 0.003 0.003
Plasmodium vivax centrin-1, putative 0.0062 0.0139 0.0546
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0018 0.0008
Schistosoma mansoni hypothetical protein 0.0213 0.0569 0.0804
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0755 0.2117 0.4504
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Mycobacterium ulcerans hydrolase 0.0027 0.004 0.1425
Leishmania major calmodulin-like protein 0.0062 0.0139 0.038
Brugia malayi GnHR receptor homolog 0.0213 0.0569 0.1208
Loa Loa (eye worm) cytochrome P450 family protein 0.0084 0.0202 0.0431
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0016 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0883 0.2482 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma brucei cytochrome P450, putative 0.0092 0.0227 0.066
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0084 0.0202 0.8864
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0122 0.0479
Brugia malayi Uncoordinated protein 44 0.0014 0.0004 0.000000020611
Toxoplasma gondii cathepsin CPC1 0.02 0.0533 0.2136
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0601 0.1677 0.4882
Leishmania major i/6 autoantigen-like protein 0.0062 0.0139 0.038
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0016 0.0034
Trypanosoma cruzi cytochrome P450, putative 0.0092 0.0227 0.0465
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0084 0.0202 0.1549
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0084 0.0202 0.8864
Brugia malayi cytochrome P450 0.0084 0.0202 0.0423
Onchocerca volvulus 0.0062 0.0139 0.0546
Echinococcus multilocularis hypothetical protein 0.0569 0.1586 0.1586
Onchocerca volvulus 0.0015 0.0007 0.0011
Entamoeba histolytica protein kinase, putative 0.0296 0.0806 0.3205
Brugia malayi Matrixin family protein 0.0022 0.0027 0.0049
Onchocerca volvulus 0.0022 0.0027 0.0092
Brugia malayi Cathepsin L-like precursor 0.0883 0.2482 0.529
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Onchocerca volvulus 0.0213 0.0569 0.2283
Trichomonas vaginalis calmodulin, putative 0.0063 0.0143 0.0541
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0165 0.0353
Schistosoma mansoni cpg binding protein 0.003 0.0048 0.0063
Schistosoma mansoni neuropeptide f receptor 76f 0.0213 0.0569 0.0804
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0165 0.1252
Trypanosoma brucei calpain-like protein, putative 0.0569 0.1586 0.4629
Trypanosoma cruzi I/6 autoantigen, putative 0.0062 0.0139 0.0277
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0147 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0883 0.2482 1
Echinococcus multilocularis neuropeptide receptor A26 0.0213 0.0569 0.0569
Leishmania major cathepsin L-like protease 0.0883 0.2482 0.7236
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Giardia lamblia Cathepsin B precursor 0.02 0.0533 0.2894
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0147 0.0307
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0145 0.0201
Trypanosoma brucei I/6 autoantigen 0.0062 0.0139 0.0404
Leishmania major calmodulin-like protein 0.0062 0.0139 0.038
Echinococcus granulosus neurocalcin 0.0062 0.0139 0.0139
Schistosoma mansoni cathepsin D (A01 family) 0.0559 0.1558 0.221
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0477 0.1323 0.386
Loa Loa (eye worm) blistered cuticle protein 3 0.0065 0.0147 0.0315
Onchocerca volvulus 0.02 0.0533 0.2135
Leishmania major hypothetical protein, conserved 0.0486 0.1349 0.392
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.0615 0.0615
Trichomonas vaginalis calmodulin, putative 0.0062 0.0139 0.0525
Onchocerca volvulus 0.0024 0.003 0.0107
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0226 0.0226
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0477 0.1323 0.2808
Loa Loa (eye worm) cysteine protease 0.0883 0.2482 0.5294
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0089 0.0171
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0477 0.1323 0.1876
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0145 0.0201
Leishmania major centrin, putative 0.0062 0.0139 0.038
Trypanosoma cruzi centrin, putative 0.007 0.0162 0.0326
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Brugia malayi cahepsin L-like non-peptiedase homolog 0.02 0.0533 0.1129
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0009 0.0025
Echinococcus granulosus peroxidasin 0.0065 0.0147 0.0147
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0587 0.1637 0.4765
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0084 0.0202 0.8864
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0297 0.0811 0.1714
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0145 0.0145
Echinococcus granulosus neuropeptide receptor 0.0213 0.0569 0.0569
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0062 0.0139 0.0277
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0427 0.1181 0.2519
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0587 0.1637 0.348
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0096 0.0197
Trichomonas vaginalis myosin light chain 1, putative 0.0062 0.0139 0.0525
Giardia lamblia Cysteine protease 0.02 0.0533 0.2894
Echinococcus granulosus calpain 5 0.0569 0.1586 0.1586
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Leishmania major trypanothione reductase 0.0047 0.0097 0.0255
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0165 0.4789
Giardia lamblia Hypothetical protein 0.0063 0.0143 0.074
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0147 0.0307
Trypanosoma brucei calmodulin, putative 0.0062 0.0139 0.0404
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0147 0.0307
Trichomonas vaginalis calmodulin-2, putative 0.0062 0.0139 0.0525
Brugia malayi TAR-binding protein 0.0064 0.0145 0.0302
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0274 0.0743 0.2986
Echinococcus granulosus rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0073
Loa Loa (eye worm) matrixin family protein 0.0049 0.0104 0.0221
Toxoplasma gondii PAN/Apple domain-containing protein 0.0015 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Leishmania major hypothetical protein, conserved 0.0024 0.003 0.0061
Brugia malayi Cathepsin L-like precursor 0.0883 0.2482 0.529
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0016 0.0051
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0213 0.0569 0.0569
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0062 0.0139 0.0404
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.046 0.1274 0.2703
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0089 0.0259
Echinococcus granulosus calcium uptake protein 1 0.0063 0.0143 0.0143
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0811 0.2275 0.663
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0147 0.0315
Onchocerca volvulus 0.0213 0.0569 0.2283
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0139 0.0193
Leishmania major receptor-type adenylate cyclase a-like protein 0.0204 0.0544 0.1564
Loa Loa (eye worm) hypothetical protein 0.0606 0.1692 0.3609
Trichomonas vaginalis calcium binding protein, putative 0.007 0.0162 0.0617
Plasmodium falciparum plasmepsin I 0.019 0.0504 0.2001
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Loa Loa (eye worm) RecQ helicase 0.0021 0.0023 0.005
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0477 0.1323 0.1876
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0004 0.0004
Trypanosoma cruzi cysteine proteinase, putative 0.0477 0.1323 0.2808
Trypanosoma brucei calmodulin, putative 0.0063 0.0143 0.0416
Loa Loa (eye worm) ctsf protein 0.0883 0.2482 0.5294
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0213 0.0569 0.0804
Trichomonas vaginalis calcineurin B subunit, putative 0.0063 0.0143 0.0541
Schistosoma mansoni opsin-like receptor 0.0213 0.0569 0.0804
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0165 0.7167
Onchocerca volvulus Peroxidase homolog 0.0065 0.0147 0.058
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0743 0.2969
Echinococcus multilocularis fmrfamide receptor 0.0213 0.0569 0.0569
Echinococcus multilocularis neuropeptide receptor 0.0213 0.0569 0.0569
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0145 0.0201
Brugia malayi Cathepsin L-like precursor 0.0606 0.1692 0.3603
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0018 0.0378
Echinococcus multilocularis allatostatin A receptor 0.0213 0.0569 0.0569
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0204 0.0544 0.1142
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0195
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.019 0.0504 0.0504
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0569 0.1586 0.3371
Schistosoma mansoni biogenic amine receptor 0.0213 0.0569 0.0804
Trypanosoma brucei caltractin, putative 0.007 0.0162 0.0471
Trypanosoma brucei calpain-like protein, putative 0.0569 0.1586 0.4629
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0297 0.0811 0.1714
Plasmodium falciparum serine repeat antigen 2 0.02 0.0533 0.2117
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0045 0.0091 0.0354
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0018 0.0378
Toxoplasma gondii thioredoxin reductase 0.0047 0.0097 0.0375
Onchocerca volvulus 0.0213 0.0569 0.2283
Plasmodium falciparum plasmepsin IX 0.0045 0.0091 0.0331
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0016 0.0048
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.02 0.0533 0.1137
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0811 0.2275 0.663
Loa Loa (eye worm) melatonin receptor type 1A 0.0213 0.0569 0.1215
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0016 0.0019
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.02 0.0533 0.0752
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0477 0.1324 0.281
Trichomonas vaginalis conserved hypothetical protein 0.033 0.0904 0.3617
Schistosoma mansoni hypothetical protein 0.0031 0.0053 0.007
Loa Loa (eye worm) hypothetical protein 0.0277 0.0753 0.1607
Leishmania major hypothetical protein, conserved 0.0204 0.0544 0.1564
Echinococcus granulosus cathepsin l cysteine peptidase 0.0883 0.2482 0.2482
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0139 0.0525
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0204 0.0544 0.1142
Trypanosoma cruzi calmodulin, putative 0.0062 0.0139 0.0277
Schistosoma mansoni cpg binding protein 0.0028 0.0044 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.02 0.0533 0.2117
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Echinococcus granulosus EF HAND 1 calcium binding site 0.0062 0.0139 0.0139
Schistosoma mansoni cathepsin D (A01 family) 0.0559 0.1558 0.221
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0883 0.2482 1
Brugia malayi Cathepsin L-like precursor 0.0883 0.2482 0.529
Echinococcus granulosus cathepsin l1 0.0606 0.1692 0.1692
Brugia malayi aspartic protease BmAsp-2, identical 0.0045 0.0091 0.0187
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0883 0.2482 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Brugia malayi EF hand family protein 0.0062 0.0139 0.0289
Brugia malayi Matrixin family protein 0.0022 0.0027 0.0049
Schistosoma mansoni neuropeptide receptor 0.0213 0.0569 0.0804
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0009 0.0022
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0091 0.0124
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1657 0.4688 0.666
Schistosoma mansoni amine GPCR 0.0213 0.0569 0.0804
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0398 0.1097 0.2325
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0018 0.0024
Trypanosoma cruzi cysteine peptidase, putative 0.1214 0.3426 0.7303
Leishmania major DNA polymerase kappa, putative 0.0019 0.0018 0.0024
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0165 0.1252
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0034 0.0123
Leishmania major small myristoylated protein 4, putative 0.0553 0.1541 0.4484
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0018 0.0049
Brugia malayi Cathepsin L-like precursor 0.0883 0.2482 0.529
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.065 0.1818 0.7315
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.0194
Brugia malayi Pepsin A precursor 0.0045 0.0091 0.0187
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0165 0.063
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0084 0.0202 0.8864
Brugia malayi EF hand family protein 0.0063 0.0143 0.0298
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0226 0.0474
Echinococcus multilocularis cathepsin L cysteine protease 0.0883 0.2482 0.2482
Brugia malayi Dopamine receptor protein 1 0.0213 0.0569 0.1208
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0297 0.0811 0.2367
Schistosoma mansoni hypothetical protein 0.0047 0.0096 0.0131
Plasmodium falciparum plasmepsin III 0.0045 0.0091 0.0331
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0091 0.0124
Echinococcus granulosus calumenin 0.0063 0.0143 0.0143
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0016 0.0026
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0267 0.2071
Toxoplasma gondii aspartyl protease ASP1 0.019 0.0504 0.2021
Giardia lamblia Cathepsin L precursor 0.02 0.0533 0.2894
Schistosoma mansoni neuropeptide F-like receptor 0.0213 0.0569 0.0804
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0084 0.0202 0.1549
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0084 0.0202 0.1549
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1672 0.4732 0.4732
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0084 0.0202 0.1549
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0007 0.0014
Schistosoma mansoni Mername-AA248 (C02 family) 0.0569 0.1586 0.225
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0062 0.0139 0.0277
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0755 0.2117 0.6177
Brugia malayi calcium-binding protein 0.0062 0.0139 0.0289
Onchocerca volvulus 0.0213 0.0569 0.2283
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0477 0.1324 0.3847
Brugia malayi cathepsin L-like cysteine proteinase 0.02 0.0533 0.1129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0213 0.0569 0.0804
Leishmania major hypothetical protein, conserved 0.0204 0.0544 0.1564
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0063 0.0143 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0084 0.0202 0.1549
Brugia malayi Cytochrome P450 family protein 0.0092 0.0227 0.0476
Loa Loa (eye worm) hypothetical protein 0.0608 0.1698 0.3622
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Echinococcus multilocularis g-protein coupled receptor 0.0213 0.0569 0.0569
Echinococcus multilocularis orexin receptor type 2 0.0213 0.0569 0.0569
Giardia lamblia Cathepsin L precursor 0.02 0.0533 0.2894
Echinococcus granulosus G protein coupled receptor 139 0.0213 0.0569 0.0569
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0023 0.0023
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.02 0.0533 0.2135
Echinococcus granulosus neuropeptides capa receptor 0.0213 0.0569 0.0569
Brugia malayi Papain family cysteine protease containing protein 0.02 0.0533 0.1129
Loa Loa (eye worm) calpain family protein 1 0.0882 0.2478 0.5287
Giardia lamblia Cathepsin B precursor 0.065 0.1818 1
Echinococcus granulosus allatostatin A receptor 0.0213 0.0569 0.0569
Plasmodium vivax plasmepsin IV, putative 0.019 0.0504 0.2019
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0569 0.1586 0.3371
Plasmodium vivax aspartyl proteinase, putative 0.019 0.0504 0.2019
Echinococcus granulosus neuropeptide receptor A26 0.0213 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0883 0.2482 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0009 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0743 0.2168
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0743 0.2969
Schistosoma mansoni biogenic amine (5HT) receptor 0.0213 0.0569 0.0804
Plasmodium falciparum plasmepsin VI 0.019 0.0504 0.2001
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0009 0.0024
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0084 0.0202 0.8864
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0213 0.0569 0.0804
Echinococcus granulosus biogenic amine 5HT receptor 0.0213 0.0569 0.0569
Brugia malayi ORL1-like opioid receptor 0.0213 0.0569 0.1208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0213 0.0569 0.0569
Echinococcus multilocularis calmodulin 0.0062 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.02 0.0533 0.1137
Loa Loa (eye worm) PAN domain-containing protein 0.0015 0.0007 0.0014
Echinococcus multilocularis G protein coupled receptor 139 0.0213 0.0569 0.0569
Toxoplasma gondii hypothetical protein 0.0274 0.0743 0.2986
Echinococcus multilocularis serotonin receptor 0.0213 0.0569 0.0569
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0084 0.0202 0.8864
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.02 0.0533 0.0752
Echinococcus granulosus neuropeptide Y receptor 0.0213 0.0569 0.0569
Echinococcus granulosus biogenic amine 5HT receptor 0.0213 0.0569 0.0569
Trypanosoma cruzi kinesin, putative 0.0296 0.0806 0.1703
Loa Loa (eye worm) calpain D 0.0274 0.0743 0.1586
Plasmodium vivax serine-repeat antigen (SERA), putative 0.02 0.0533 0.2135
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0084 0.0202 0.8864
Brugia malayi Cytochrome P450 family protein 0.0084 0.0202 0.0423
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0606 0.1692 0.6804
Trypanosoma cruzi cysteine proteinase, putative 0.0477 0.1323 0.2808
Echinococcus granulosus orexin receptor type 2 0.0213 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Mycobacterium ulcerans lipase LipD 0.0071 0.0165 0.7167
Plasmodium falciparum plasmepsin II 0.019 0.0504 0.2001
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0018 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Schistosoma mansoni calpain-7 (C02 family) 0.0569 0.1586 0.225
Echinococcus multilocularis neuropeptides capa receptor 0.0213 0.0569 0.0569
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0544 0.1142
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0145 0.0201
Echinococcus multilocularis neuropeptide FF receptor 2 0.0213 0.0569 0.0569
Brugia malayi hypothetical protein 0.0016 0.0009 0.0011
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0213 0.0569 0.0569
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1239 0.3497 0.4967
Loa Loa (eye worm) G-protein coupled receptor 0.0213 0.0569 0.1215
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0034 0.0053
Onchocerca volvulus 0.0027 0.0039 0.0143
Toxoplasma gondii PAN domain-containing protein 0.0015 0.0007 0.0013
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0084 0.0202 0.8864
Mycobacterium tuberculosis Conserved protein 0.0071 0.0165 0.1252
Echinococcus multilocularis neuronal calcium sensor 0.0062 0.0139 0.0139
Giardia lamblia Cathepsin B precursor 0.065 0.1818 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0267 0.2071
Onchocerca volvulus 0.0213 0.0569 0.2283
Leishmania major DNA polymerase eta, putative 0.0044 0.0089 0.0234
Onchocerca volvulus 0.0015 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0071 0.0165 0.0353
Entamoeba histolytica cysteine protease, putative 0.02 0.0533 0.2097
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0213 0.0569 0.0804
Plasmodium falciparum centrin-1 0.0062 0.0139 0.0525
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Trypanosoma brucei centrin, putative 0.0062 0.0139 0.0404
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0213 0.0569 0.0569
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0213 0.0569 0.1208
Schistosoma mansoni rab 0.0062 0.0139 0.0193
Brugia malayi cathepsin Z-like cysteine proteinase 0.02 0.0533 0.1129
Trypanosoma cruzi kinesin, putative 0.0296 0.0806 0.1703
Entamoeba histolytica cysteine proteinase, putative 0.0477 0.1323 0.5301
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0023 0.0042
Plasmodium falciparum serine repeat antigen 4 0.02 0.0533 0.2117
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0165 0.7167
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0318 0.0318
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0091 0.0124
Giardia lamblia Cathepsin B precursor 0.02 0.0533 0.2894
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0084 0.0202 0.1549
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0018 0.002
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0084 0.0202 0.8864
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0827 0.2322 0.4943
Echinococcus granulosus 7TM GPCR rhodopsin 0.0213 0.0569 0.0569
Brugia malayi Pre-SET motif family protein 0.0062 0.0139 0.029
Toxoplasma gondii microneme protein MIC4 0.0015 0.0007 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.02 0.0533 0.2117
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0811 0.2275 0.4842
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0213 0.0569 0.0569
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0084 0.0202 0.1549
Echinococcus multilocularis dna polymerase eta 0.0044 0.0089 0.0089
Plasmodium vivax aspartyl proteinase, putative 0.0045 0.0091 0.0352
Giardia lamblia Cathepsin L precursor 0.02 0.0533 0.2894
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0034 0.0053
Echinococcus granulosus calpain A 0.0569 0.1586 0.1586
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Brugia malayi Peroxidasin 0.0065 0.0147 0.0307
Schistosoma mansoni biogenic amine receptor 0.0213 0.0569 0.0804
Echinococcus granulosus g protein coupled receptor 0.0213 0.0569 0.0569
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0213 0.0569 0.0804
Brugia malayi putative neuropeptide receptor 0.0213 0.0569 0.1208
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0084 0.0202 0.8864
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Echinococcus multilocularis peroxidasin 0.0065 0.0147 0.0147
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0619 0.1727 0.3672
Brugia malayi PAN domain containing protein 0.0015 0.0007 0.0006
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0034 0.0098
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.065 0.1818 0.2579
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0226 0.0226
Schistosoma mansoni lamin 0.0027 0.0039 0.005
Entamoeba histolytica calpain family cysteine protease, putative 0.0274 0.0743 0.2951
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.003 0.0045
Loa Loa (eye worm) cytochrome P450 0.0084 0.0202 0.0431
Trypanosoma cruzi centrin, putative 0.007 0.0162 0.0326
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0213 0.0569 0.0804
Brugia malayi Matrixin family protein 0.0022 0.0027 0.0049
Toxoplasma gondii aspartyl protease 0.0045 0.0091 0.0354
Loa Loa (eye worm) EF hand family protein 0.0062 0.0139 0.0297
Brugia malayi MH2 domain containing protein 0.0122 0.0311 0.0656
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0274 0.0743 0.2969
Loa Loa (eye worm) cytochrome P450 family protein 0.0092 0.0227 0.0484
Onchocerca volvulus 0.0883 0.2482 1
Loa Loa (eye worm) calpain family protein 1 0.1177 0.3321 0.7085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Plasmodium vivax vivapain-3 0.0477 0.1323 0.5323
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0827 0.2322 0.6769
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0213 0.0569 0.0804
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0883 0.2482 1
Plasmodium vivax vivapain-1 0.0477 0.1323 0.5323
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0004 0.000000013728
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0039 0.0084
Brugia malayi Serotonin receptor 0.0213 0.0569 0.1208
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0004 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0477 0.1323 0.5301
Giardia lamblia Dipeptidyl-peptidase I precursor 0.02 0.0533 0.2894
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0811 0.2275 0.4842
Toxoplasma gondii kringle domain-containing protein 0.0024 0.003 0.0108
Schistosoma mansoni calpain-2 (C02 family) 0.0274 0.0743 0.1052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0213 0.0569 0.0569
Echinococcus multilocularis tachykinin peptides receptor 99D 0.352 1 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0165 0.0353
Toxoplasma gondii microneme protein, putative 0.0015 0.0007 0.0013
Echinococcus multilocularis centrin 2 0.0062 0.0139 0.0139
Brugia malayi beta-lactamase 0.0071 0.0165 0.0345
Trichomonas vaginalis set domain proteins, putative 0.0486 0.1349 0.5418
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.02 0.0533 0.0752
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0084 0.0202 0.8864
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0171 0.0171
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0034 0.0124
Trypanosoma brucei unspecified product 0.0204 0.0544 0.1585
Schistosoma mansoni ap endonuclease 0.0018 0.0016 0.0017
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0089 0.0183
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0062 0.0139 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Brugia malayi Protein kinase domain containing protein 0.0014 0.0004 0.000000020611
Plasmodium falciparum cysteine proteinase falcipain 1 0.0477 0.1323 0.5313
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0165 0.1252
Mycobacterium tuberculosis Probable reductase 0.0107 0.0267 0.2071
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0165 0.1252
Plasmodium falciparum serine repeat antigen 6 0.02 0.0533 0.2117
Onchocerca volvulus Matrilysin homolog 0.0049 0.0104 0.0403
Trichomonas vaginalis calmodulin, putative 0.0062 0.0139 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0049
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0755 0.2117 0.4504
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Schistosoma mansoni cathepsin S (C01 family) 0.02 0.0533 0.0752
Echinococcus multilocularis neuropeptide receptor 0.0213 0.0569 0.0569
Entamoeba histolytica cysteine protease, putative 0.02 0.0533 0.2097
Echinococcus multilocularis calcium uptake protein 1 0.0063 0.0143 0.0143
Echinococcus multilocularis cpg binding protein 0.003 0.0048 0.0048
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Schistosoma mansoni hypothetical protein 0.0084 0.0202 0.0282
Entamoeba histolytica cysteine protease, putative 0.0883 0.2482 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0937 0.2636 0.5614
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0883 0.2482 1
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.02 0.0533 0.2135
Plasmodium vivax vivapain-2 0.0883 0.2482 1
Schistosoma mansoni centrin 0.0062 0.0139 0.0193
Echinococcus multilocularis somatostatin receptor 0.0213 0.0569 0.0569
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0045 0.0091 0.0124
Brugia malayi Melatonin receptor type 1A 0.0213 0.0569 0.1208
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0301 1
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0165 0.0651
Trypanosoma cruzi hypothetical protein, conserved 0.033 0.0904 0.1911
Echinococcus granulosus cathepsin l1 0.0883 0.2482 0.2482
Trypanosoma brucei calpain, putative 0.0274 0.0743 0.2168
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0477 0.1323 0.5313
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Echinococcus multilocularis cathepsin L 0.02 0.0533 0.0533
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0258 0.0699 0.2038
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Trypanosoma brucei calpain-like protein, putative 0.0827 0.2322 0.6777
Trypanosoma brucei Calpain-like protein 1.1 0.0811 0.2275 0.6639
Plasmodium vivax unspecified product 0.02 0.0533 0.2135
Trypanosoma cruzi major cysteine proteinase, putative 0.0531 0.1477 0.3137
Schistosoma mansoni alpha-1 adrenergic receptor 0.0213 0.0569 0.0804
Echinococcus granulosus cathepsin L 0.02 0.0533 0.0533
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0315
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0084 0.0202 0.1549
Onchocerca volvulus Chorion peroxidase homolog 0.0065 0.0147 0.058
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0883 0.2482 0.2482
Echinococcus multilocularis cathepsin b 0.1657 0.4688 0.4688
Leishmania major cathepsin L-like protease 0.1214 0.3426 1
Echinococcus granulosus neuropeptide Y receptor 0.0213 0.0569 0.0569
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0619 0.1727 0.3672
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0477 0.1324 0.3863
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0009 0.5
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0147 0.0315
Brugia malayi glutathione reductase 0.0047 0.0097 0.0198
Trypanosoma brucei Calpain-like protein CALP1.3 0.0477 0.1324 0.3863
Trypanosoma cruzi cysteine peptidase, putative 0.0477 0.1323 0.2808
Trichomonas vaginalis hypothetical protein 0.0274 0.0743 0.2969
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0147 0.0315
Onchocerca volvulus 0.0213 0.0569 0.2283
Trypanosoma brucei Calpain-like protein 1.2 0.0619 0.1727 0.5041
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1657 0.4688 0.666
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0213 0.0569 0.0804
Plasmodium falciparum serine repeat antigen 7 0.02 0.0533 0.2117
Brugia malayi Papain family cysteine protease containing protein 0.02 0.0533 0.1129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0226 0.0316
Brugia malayi calpain 5 0.0274 0.0743 0.1579
Echinococcus granulosus lamin 0.0027 0.0039 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0084 0.0202 0.1549
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0883 0.2482 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0258 0.0699 0.2038
Trypanosoma brucei small myristoylated protein 1-2 0.0351 0.0965 0.2814
Giardia lamblia DINP protein human, muc B family 0.0019 0.0018 0.0045
Onchocerca volvulus 0.0213 0.0569 0.2283
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0213 0.0569 0.0569
Schistosoma mansoni opsin-like receptor 0.0213 0.0569 0.0804
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0204 0.0544 0.1585
Echinococcus multilocularis fmrfamide receptor 0.0213 0.0569 0.0569
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0213 0.0569 0.0804
Leishmania major META domain containing protein 0.0204 0.0544 0.1564
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1214 0.3426 1
Giardia lamblia Cathepsin L precursor 0.02 0.0533 0.2894
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0014
Echinococcus granulosus death domain containing protein 0.0014 0.0004 0.0004
Schistosoma mansoni calmodulin 0.0062 0.0139 0.0193
Loa Loa (eye worm) hypothetical protein 0.0062 0.0139 0.0298
Plasmodium vivax vivapain-2 0.0883 0.2482 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0139 0.0139
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Trypanosoma cruzi small myristoylated protein 1-1 0.0351 0.0965 0.2042
Echinococcus granulosus lamin dm0 0.0027 0.0039 0.0039
Leishmania major centrin, putative,caltractin, putative 0.0062 0.0139 0.038
Brugia malayi hypothetical protein 0.0213 0.0569 0.1208
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0606 0.1692 0.3609
Brugia malayi RE15519p 0.0213 0.0569 0.1208
Mycobacterium leprae putative cytochrome p450 0.0084 0.0202 0.6204
Leishmania major hypothetical protein, conserved 0.0063 0.0143 0.0392
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0477 0.1324 0.281
Echinococcus granulosus neuropeptide s receptor 0.0213 0.0569 0.0569
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0071 0.0165 0.0353
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0139 0.0193
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0016 0.0026
Brugia malayi cathepsin L-like precursor 0.0606 0.1692 0.3603
Loa Loa (eye worm) hypothetical protein 0.0071 0.0165 0.0353
Entamoeba histolytica cysteine protease, putative 0.0477 0.1323 0.5301
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0081 0.0194 0.0194
Echinococcus granulosus dro:myosuppressin receptor 0.0213 0.0569 0.0569
Loa Loa (eye worm) cytochrome P450 family protein 0.0092 0.0227 0.0484
Schistosoma mansoni hypothetical protein 0.0035 0.0064 0.0085
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0477 0.1324 0.281
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0057
Trypanosoma cruzi cysteine peptidase, putative 0.1214 0.3426 0.7303
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.02 0.0533 0.2117
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0023 0.0056
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0052 0.0091
Loa Loa (eye worm) hypothetical protein 0.0213 0.0569 0.1215
Brugia malayi hypothetical protein 0.0045 0.0091 0.0187
Giardia lamblia Cathepsin B precursor 0.065 0.1818 1
Schistosoma mansoni intermediate filament proteins 0.0027 0.0039 0.005
Trichomonas vaginalis calmodulin, putative 0.0062 0.0139 0.0525
Trypanosoma brucei small myristoylated protein 1-1 0.0351 0.0965 0.2814
Onchocerca volvulus 0.0883 0.2482 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0016 0.0292
Echinococcus granulosus neuropeptide receptor 0.0213 0.0569 0.0569
Trichomonas vaginalis calmodulin, putative 0.007 0.0162 0.0617

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 7 uM Concentration required for 50% inhibition of binding against Angiotensin II receptor in the rat adrenal cortex tissue ChEMBL. No reference
IC50 (binding) = 7 uM Concentration required for 50% inhibition of binding against Angiotensin II receptor in the rat adrenal cortex tissue ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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