Detailed information for compound 1509308

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 526.333 | Formula: C25H20BrNO7
  • H donors: 1 H acceptors: 2 LogP: 5.15 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc2c(c1)OC(C(C2=O)OC(=O)Nc1ccc(c(c1)Br)C)c1ccc2c(c1)OCO2
  • InChi: 1S/C25H20BrNO7/c1-13-3-5-15(10-18(13)26)27-25(29)34-24-22(28)17-7-6-16(30-2)11-20(17)33-23(24)14-4-8-19-21(9-14)32-12-31-19/h3-11,23-24H,12H2,1-2H3,(H,27,29)
  • InChiKey: KVWWZXIMTCPSMS-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0055 0.0113 0.0113
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0006 0.0027
Schistosoma mansoni histone deacetylase 0.0366 0.1001 0.1001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0056 0.0076
Brugia malayi Calcium binding EGF domain containing protein 0.0452 0.1246 0.1683
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0044 0.0082 0.011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Onchocerca volvulus 0.0065 0.0142 0.0179
Schistosoma mansoni lipoxygenase 0.0837 0.2345 0.2345
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.001 0.0013
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0109 0.0267 0.0267
Mycobacterium ulcerans glyoxalase GloA 0.0044 0.0082 0.0414
Giardia lamblia GTOR 0.0044 0.0083 0.062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Echinococcus granulosus neuropeptide Y receptor 0.0065 0.0142 0.0142
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.0097 0.077
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0065 0.0142 0.0142
Brugia malayi lactoylglutathione lyase 0.0189 0.0496 0.0669
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0057 0.0121 0.0121
Loa Loa (eye worm) animal heme peroxidase 0.261 0.7403 1
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0031 0.0055
Schistosoma mansoni neuropeptide receptor 0.0065 0.0142 0.0142
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0362
Toxoplasma gondii histone deacetylase HDAC5 0.0131 0.0332 0.2656
Plasmodium falciparum cysteine proteinase falcipain 3 0.0051 0.0102 0.1009
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Plasmodium vivax histone deacetylase 2, putative 0.0131 0.0331 0.3303
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0036 0.006 0.0296
Echinococcus granulosus g protein coupled receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis neuropeptide Y receptor 0.0065 0.0142 0.0142
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.0776 1
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0001 0.0001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0131 0.0131
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0065 0.0142 0.0142
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0103 0.0103
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0083 0.0581
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0036 0.006 0.0296
Schistosoma mansoni glutamate receptor kainate 0.0064 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.0776 0.6207
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Echinococcus granulosus pyruvate kinase 0.0018 0.0008 0.0008
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.001 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0031 0.0129
Schistosoma mansoni glutamate receptor NMDA 0.0152 0.0391 0.0391
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0176 0.0176
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0016 0.0003 0.0003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0079 0.0365
Onchocerca volvulus Slit protein homolog 0.0452 0.1246 0.1672
Trypanosoma cruzi p450 reductase, putative 0.0026 0.0032 0.0169
Echinococcus granulosus glutamate receptor subunit protein glur 0.0024 0.0024 0.0024
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0082 0.0381
Brugia malayi glutathione reductase 0.005 0.0098 0.0132
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0109 0.0267 0.036
Plasmodium falciparum glyoxalase I 0.0044 0.0082 0.0808
Brugia malayi histone deacetylase 3 (HD3) 0.0366 0.1001 0.1351
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.0014
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0036 0.006 0.0296
Schistosoma mansoni fatty acid binding protein 0.0034 0.0054 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0081 0.0109
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.0097 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis protein jagged 1 0.0452 0.1246 0.1246
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Schistosoma mansoni hypothetical protein 0.0024 0.0024 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0036 0.006 0.0296
Brugia malayi larval opioid receptor 0.0065 0.0142 0.0191
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.004
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0057 0.0121 0.0163
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0031 0.0031
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0102 0.0482
Schistosoma mansoni pol-related 0.0111 0.0275 0.0275
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Entamoeba histolytica cysteine protease, putative 0.0051 0.0102 0.0776
Brugia malayi Peroxidasin 0.261 0.7403 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0102 0.0137
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0065 0.0142 0.0192
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0065 0.0142 0.0142
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0109 0.0267 0.0267
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0065 0.0142 0.0191
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Giardia lamblia High cysteine protein 0.0452 0.1246 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0065 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Loa Loa (eye worm) hypothetical protein 0.0185 0.0485 0.0656
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0457 0.2267
Schistosoma mansoni hypothetical protein 0.0251 0.0672 0.0672
Plasmodium vivax histone deacetylase, putative 0.0131 0.0331 0.3303
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0086 0.0116
Onchocerca volvulus 0.261 0.7403 1
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0035 0.0034
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0189 0.0496 0.2699
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0083 0.0447
Mycobacterium tuberculosis Conserved protein 0.0044 0.0082 0.0414
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Trichomonas vaginalis set domain proteins, putative 0.0715 0.1997 1
Leishmania major cytochrome p450-like protein 0.0036 0.006 0.0323
Echinococcus granulosus intermediate filament protein 0.0114 0.0281 0.0281
Brugia malayi Muscle positioning protein 4 0.0452 0.1246 0.1683
Brugia malayi Cytochrome P450 family protein 0.0075 0.017 0.0229
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0076 0.0174 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Echinococcus granulosus pyruvate kinase 0.0018 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0036 0.006 0.0296
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.003 0.0233
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus fatty acid binding protein FABP2 0.0034 0.0054 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Echinococcus multilocularis Polycystic kidney disease protein 0.014 0.0356 0.0356
Brugia malayi Histone deacetylase 1 0.0366 0.1001 0.1351
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0036 0.006 0.0296
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0065 0.0142 0.0191
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0174 0.0454 0.0454
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0001
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0035 0.0034
Onchocerca volvulus 0.0034 0.0054 0.0059
Schistosoma mansoni lamin 0.0114 0.0281 0.0281
Trypanosoma cruzi cruzipain precursor, putative 0.0193 0.0509 0.277
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus granulosus protein jagged 2 0.0452 0.1246 0.1246
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.0005
Brugia malayi Thioredoxin reductase 0.005 0.0098 0.0132
Echinococcus multilocularis neuropeptide receptor A26 0.2015 0.5705 0.5705
Schistosoma mansoni alpha-1 adrenergic receptor 0.0065 0.0142 0.0142
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0035 0.0046
Loa Loa (eye worm) animal heme peroxidase 0.261 0.7403 1
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0095
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0109 0.0267 0.0267
Loa Loa (eye worm) DR-78 0.0051 0.0103 0.0139
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0031 0.0055
Leishmania major histone deacetylase, putative 0.0131 0.0331 0.1801
Schistosoma mansoni polycystin 1-related 0.014 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Onchocerca volvulus Phospholipase A2 homolog 0.0185 0.0485 0.0643
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0109 0.0267 0.0267
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Echinococcus granulosus aldehyde reductase 0.0066 0.0146 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0031 0.0128
Onchocerca volvulus 0.0111 0.0275 0.0358
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Echinococcus multilocularis FTZ F1 alpha 0.0109 0.0267 0.0267
Echinococcus multilocularis histone deacetylase 1 0.0366 0.1001 0.1001
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0109 0.0267 0.0267
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Echinococcus multilocularis neuropeptides capa receptor 0.0065 0.0142 0.0142
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0035 0.0186
Toxoplasma gondii histone deacetylase HDAC4 0.0131 0.0331 0.2653
Echinococcus multilocularis sex peptide receptor 0.0065 0.0142 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0036 0.006 0.0296
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0065 0.0142 0.0142
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0098 0.0133
Plasmodium vivax glyoxalase I, putative 0.0189 0.0496 0.495
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Schistosoma mansoni rab6-interacting 0.014 0.0356 0.0356
Echinococcus multilocularis lipoxygenase domain containing protein 0.014 0.0356 0.0356
Onchocerca volvulus 0.0027 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Schistosoma mansoni zinc finger protein 0.0051 0.0103 0.0103
Echinococcus granulosus protein jagged 1 0.0452 0.1246 0.1246
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Echinococcus granulosus dro:myosuppressin receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0014
Echinococcus granulosus neuropeptide receptor A26 0.2015 0.5705 0.5705
Echinococcus multilocularis epidermal growth factor receptor 0.0146 0.0375 0.0375
Echinococcus multilocularis peroxidasin 0.261 0.7403 0.7403
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0275 0.135
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0776 0.7689
Trypanosoma brucei histone deacetylase 3 0.0131 0.0331 0.1801
Brugia malayi Cytochrome P450 family protein 0.0045 0.0086 0.0115
Brugia malayi Dopamine receptor 0.0065 0.0142 0.0191
Brugia malayi hypothetical protein 0.0057 0.0121 0.0162
Schistosoma mansoni histone deacetylase hda2 0.0131 0.0331 0.0331
Brugia malayi hypothetical protein 0.0017 0.0004 0.0004
Onchocerca volvulus 0.0111 0.0275 0.0358
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Onchocerca volvulus 0.0065 0.0142 0.0179
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0006 0.005
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0083 0.0447
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0065 0.0142 0.0142
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0035 0.0046
Leishmania major cytochrome p450-like protein 0.0045 0.0086 0.0465
Loa Loa (eye worm) hypothetical protein 0.0055 0.0113 0.0153
Brugia malayi Cytochrome P450 family protein 0.0045 0.0086 0.0115
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0047 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Brugia malayi nuclear hormone receptor family member odr-7 0.0051 0.0103 0.0138
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0051 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.0279 0.1495
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0076 0.0174 0.0174
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0056 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.01 0.0241 0.0326
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0006 0.0027
Echinococcus multilocularis lamin 0.0114 0.0281 0.0281
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0065 0.0142 0.0142
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Echinococcus multilocularis RUN 0.014 0.0356 0.0356
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0031 0.0055
Plasmodium vivax histone deacetylase, putative 0.0131 0.0331 0.3303
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0031 0.0041
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0174 0.0454 0.0612
Echinococcus granulosus slit 2 protein 0.0452 0.1246 0.1246
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0275 0.037
Loa Loa (eye worm) animal heme peroxidase 0.261 0.7403 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0057 0.0307
Trypanosoma brucei histone deacetylase 1 0.0366 0.1001 0.5454
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0036 0.006 0.0296
Brugia malayi M-phase phosphoprotein, mpp8 0.0099 0.0241 0.0324
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0026 0.0032 0.0169
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus granulosus cathepsin L cysteine proteinase 0.0051 0.0102 0.0102
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0067 0.0336
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0007 0.0005
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0432 0.057
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis pyruvate kinase 0.0018 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0036 0.006 0.0296
Trypanosoma brucei aldo/keto reductase, putative 0.0045 0.0085 0.0462
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0142 0.0142
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0045 0.0085 0.0085
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0036 0.006 0.0296
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0109 0.0267 0.0267
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0142 0.0142
Brugia malayi Protein kinase domain containing protein 0.0047 0.009 0.0121
Echinococcus granulosus cysteine protease 0.0026 0.0031 0.0031
Echinococcus granulosus neuropeptide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni biogenic amine receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Brugia malayi Nuclear hormone receptor-like 1 0.0109 0.0267 0.036
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Mycobacterium ulcerans oxidoreductase 0.0111 0.0275 0.1469
Brugia malayi Dopamine receptor protein 2 0.0065 0.0142 0.0191
Onchocerca volvulus 0.0065 0.0142 0.0179
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0006 0.005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Loa Loa (eye worm) hypothetical protein 0.0189 0.0496 0.067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0081 0.0109
Loa Loa (eye worm) hypothetical protein 0.0187 0.0491 0.0663
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0217 0.0217
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0058 0.0077
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Brugia malayi nuclear receptor NHR-88 0.0109 0.0267 0.036
Echinococcus multilocularis neurogenic locus protein delta 0.0452 0.1246 0.1246
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0217 0.1738
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Echinococcus granulosus cathepsin l1 0.0051 0.0102 0.0102
Leishmania major cathepsin L-like protease 0.0193 0.0509 0.277
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0065 0.0142 0.0142
Schistosoma mansoni opsin-like receptor 0.0065 0.0142 0.0142
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0056 0.0275
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0083 0.0112
Echinococcus granulosus g-protein coupled receptor 0.0065 0.0142 0.0142
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.0279 0.1495
Brugia malayi hypothetical protein 0.0027 0.0035 0.0046
Brugia malayi AKH receptor 0.0065 0.0142 0.0191
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0371 0.0371
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0008 0.0056
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0056 0.0076
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0051 0.0103 0.0126
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Echinococcus granulosus voltage gated potassium channel subunit 0.0045 0.0085 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0041 0.0178
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.01 0.0242 0.0242
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Echinococcus granulosus insulin receptor 0.0047 0.009 0.009
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0081 0.0646
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0067 0.0308
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0036 0.006 0.0296
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0452 0.1246 0.1672
Brugia malayi Histone deacetylase family protein 0.0131 0.0331 0.0446
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0036 0.006 0.0296
Echinococcus granulosus geminin 0.0346 0.0945 0.0945
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0031 0.0055
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0065 0.0142 0.0142
Brugia malayi GCC2 and GCC3 family protein 0.0452 0.1246 0.1683
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.014 0.0356 0.0481
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.0505 0.0505
Leishmania major protein kinase, putative 0.0016 0.0004 0.0016
Schistosoma mansoni loxhd1 0.014 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus multilocularis follistatin 0.0019 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0016 0.0082
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis G-protein coupled receptor, putative 0.0065 0.0142 0.0142
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0083 0.0447
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0097 0.0959
Leishmania major histone deacetylase, putative 0.0131 0.0331 0.1801
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0036 0.006 0.0296
Brugia malayi PAS domain containing protein 0.0048 0.0093 0.0125
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0006
Mycobacterium tuberculosis Probable reductase 0.0113 0.0279 0.1495
Mycobacterium tuberculosis Conserved protein TB27.3 0.0044 0.0082 0.0414
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus granulosus fibropellin Ia 0.0452 0.1246 0.1246
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0051 0.0102 0.1009
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0065 0.0142 0.0142
Schistosoma mansoni histone deacetylase 0.0366 0.1001 0.1001
Schistosoma mansoni inositol monophosphatase 0.0039 0.0067 0.0067
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Brugia malayi conserved hypotetical protein 0.0051 0.0103 0.0138
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Plasmodium vivax glyoxalase I, putative 0.0044 0.0082 0.0808
Brugia malayi hypothetical protein 0.016 0.0414 0.0558
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0209 0.0209
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0119 0.0566
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0031 0.0031
Brugia malayi Tachykinin-like peptides receptor 99D 0.0065 0.0142 0.0191
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0051 0.0102 0.1009
Brugia malayi steroid hormone receptor 0.0109 0.0267 0.036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0006
Schistosoma mansoni nuclear receptor 0.0051 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0091 0.0217 0.0293
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0509 0.277
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Echinococcus granulosus Nuclear hormone receptor HR96 0.0051 0.0103 0.0103
Schistosoma mansoni neuropeptide f receptor 76f 0.0065 0.0142 0.0142
Echinococcus granulosus dnaJ subfamily B 0.0427 0.1174 0.1174
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0036 0.006 0.0296
Leishmania major aldo-keto reductase-like protein 0.0111 0.0275 0.1493
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0036 0.006 0.0296
Brugia malayi Histone deacetylase family protein 0.0131 0.0331 0.0446
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0056 0.0302
Brugia malayi Cytochrome P450 family protein 0.0036 0.006 0.008
Onchocerca volvulus 0.0111 0.0275 0.0358
Entamoeba histolytica aldose reductase, putative 0.0111 0.0275 0.2549
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Toxoplasma gondii thioredoxin reductase 0.005 0.0098 0.0782
Brugia malayi Cathepsin L-like precursor 0.0034 0.0054 0.0072
Onchocerca volvulus 0.0065 0.0142 0.0179
Schistosoma mansoni biogenic amine receptor 0.0065 0.0142 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0054 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0109 0.0267 0.036
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis fmrfamide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0065 0.0142 0.0191
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0102 0.0124
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus multilocularis aldo keto reductase 0.0111 0.0275 0.0275
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0109 0.0267 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0275 0.037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Mycobacterium leprae Conserved hypothetical protein 0.0036 0.006 0.0145
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0051 0.0103 0.0103
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0102 0.0102
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Echinococcus multilocularis methionine synthase reductase 0.0016 0.0003 0.0003
Echinococcus multilocularis neurogenic locus protein delta 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Onchocerca volvulus Putative cubilin 0.0452 0.1246 0.1672
Mycobacterium tuberculosis Probable oxidoreductase 0.0111 0.0275 0.1469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0095
Brugia malayi photoreceptor-specific nuclear receptor 0.0109 0.0267 0.036
Brugia malayi FAD binding domain containing protein 0.0016 0.0003 0.0003
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0065 0.0142 0.0191
Trypanosoma brucei histone deacetylase 4 0.0131 0.0331 0.1801
Schistosoma mansoni cathepsin s 0.0017 0.0005 0.0005
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0083 0.0083
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0102 0.0102
Onchocerca volvulus 0.0065 0.0142 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0109 0.0267 0.036
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Loa Loa (eye worm) histone deacetylase 11 0.0131 0.0331 0.0447
Schistosoma mansoni glutamate receptor AMPA 0.0064 0.014 0.014
Echinococcus multilocularis G protein coupled receptor 139 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0217 0.0217
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.01 0.0242 0.0326
Echinococcus granulosus ecdysone induced protein 78C 0.0109 0.0267 0.0267
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0316 0.0858 0.1158
Brugia malayi hypothetical protein 0.0051 0.0103 0.0138
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0065 0.0142 0.0142
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0076 0.0174 0.0174
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) histone deacetylase 1 0.0366 0.1001 0.1352
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.01 0.0242 0.0242
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Echinococcus granulosus GPCR family 2 0.01 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0059
Mycobacterium leprae conserved hypothetical protein 0.0049 0.0097 0.1362
Loa Loa (eye worm) TK/INSR protein kinase 0.0047 0.009 0.0122
Echinococcus granulosus RUN 0.014 0.0356 0.0356
Plasmodium vivax vivapain-2 0.0051 0.0102 0.1009
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Schistosoma mansoni tyrosine kinase 0.0078 0.0179 0.0179
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0142 0.0142
Brugia malayi N-terminal motif family protein 0.0187 0.0491 0.0662
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0065 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus granulosus neuropeptides capa receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0073
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0076 0.0174 0.0174
Brugia malayi Steroid receptor seven-up type 2 0.0109 0.0267 0.036
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.0505 0.0505
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0102 0.0137
Loa Loa (eye worm) hypothetical protein 0.0174 0.0454 0.0613
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0008 0.007
Schistosoma mansoni cpg binding protein 0.006 0.0129 0.0129
Toxoplasma gondii cytochrome p450 superfamily protein 0.0036 0.006 0.0476
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Loa Loa (eye worm) melatonin receptor type 1A 0.0065 0.0142 0.0192
Schistosoma mansoni steroid hormone receptor ad4bp 0.0109 0.0267 0.0267
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Schistosoma mansoni hypothetical protein 0.0065 0.0142 0.0142
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0102 0.0776
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0034 0.0054 0.0072
Echinococcus granulosus cpg binding protein 0.0064 0.0139 0.0139
Echinococcus multilocularis dro:myosuppressin receptor 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0065 0.0142 0.0179
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0275 0.135
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0102 0.0776
Echinococcus granulosus glutamate receptor NMDA 0.0126 0.0316 0.0316
Echinococcus granulosus sex peptide receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis 0.0036 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0216 0.0573 0.0773
Loa Loa (eye worm) ctsf protein 0.0051 0.0102 0.0137
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Loa Loa (eye worm) hypothetical protein 0.0099 0.0241 0.0325
Brugia malayi neuropeptide F receptor 0.0065 0.0142 0.0191
Trypanosoma brucei prostaglandin f synthase 0.0111 0.0275 0.1493
Echinococcus granulosus histone deacetylase 3 0.0366 0.1001 0.1001
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0024 0.0024 0.0024
Loa Loa (eye worm) blistered cuticle protein 3 0.261 0.7403 1
Entamoeba histolytica hypothetical protein 0.0076 0.0174 0.1514
Echinococcus granulosus serotonin receptor 0.0065 0.0142 0.0142
Echinococcus granulosus Nuclear hormone receptor HR96 0.0051 0.0103 0.0103
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0027
Echinococcus granulosus histone deacetylase 6 0.0131 0.0331 0.0331
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Entamoeba histolytica hypothetical protein 0.0076 0.0174 0.1514
Schistosoma mansoni pyruvate kinase 0.0018 0.0008 0.0008
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0083 0.0581
Echinococcus granulosus histone deacetylase 1 0.0366 0.1001 0.1001
Echinococcus granulosus cytochrome P450 2K1 0.0036 0.006 0.006
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0035 0.0035
Toxoplasma gondii histone deacetylase HDAC2 0.0366 0.1001 0.8032
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0072 0.0332
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0102 0.0249 0.0323
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0057 0.0121 0.0121
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0031 0.0167
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0054 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0031 0.0167
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.0315 0.1691
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.1299 0.1299
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0051 0.0103 0.0103
Brugia malayi nuclear hormone receptor 0.0051 0.0103 0.0138
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Echinococcus multilocularis fmrfamide receptor 0.0065 0.0142 0.0142
Brugia malayi sulfakinin receptor protein 0.0065 0.0142 0.0191
Mycobacterium ulcerans hypothetical protein 0.0045 0.0085 0.0435
Brugia malayi Pre-SET motif family protein 0.0091 0.0217 0.0292
Giardia lamblia Histone deacetylase 0.0366 0.1001 0.8024
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0082 0.0414
Loa Loa (eye worm) hypothetical protein 0.0366 0.1001 0.1352
Plasmodium vivax unspecified product 0.0026 0.0031 0.0307
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0302 0.242
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0006 0.0027
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Echinococcus granulosus cathepsin l1 0.0034 0.0054 0.0054
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0119 0.0159
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0056 0.0014
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0065 0.0142 0.0191
Echinococcus granulosus lipoxygenase domain containing protein 0.014 0.0356 0.0356
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0231 0.0311
Brugia malayi Phospholipase A2 family protein 0.0185 0.0485 0.0655
Plasmodium falciparum histone deacetylase 1 0.0366 0.1001 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0109 0.0267 0.036
Brugia malayi follicle stimulating hormone receptor 0.0065 0.0142 0.0191
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0658 0.1835 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus granulosus delta-like protein 1 0.0452 0.1246 0.1246
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.003 0.0158
Brugia malayi nuclear receptor RXR 0.0051 0.0103 0.0138
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0065 0.0142 0.0142
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0079 0.0625
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Mycobacterium tuberculosis Conserved protein 0.0044 0.0082 0.0414
Echinococcus multilocularis neuropeptides capa receptor 0.0065 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0109 0.0267 0.036
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0044 0.0082 0.0082
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.0279 0.1495
Brugia malayi Dopamine receptor protein 1 0.0065 0.0142 0.0191
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Loa Loa (eye worm) Notch2 0.0452 0.1246 0.1683
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Brugia malayi RE15519p 0.0065 0.0142 0.0191
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Echinococcus granulosus glutamate receptor 2 0.0053 0.0107 0.0107
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0109 0.0267 0.0267
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Schistosoma mansoni coup transcription factor 0.0109 0.0267 0.0267
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0452 0.1246 0.1246
Toxoplasma gondii EGF family domain-containing protein 0.0452 0.1246 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0027 0.0035 0.0034
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0056 0.0275
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0056 0.0302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Toxoplasma gondii glyoxalase family protein 0.0044 0.0082 0.0649
Onchocerca volvulus Peroxidase homolog 0.261 0.7403 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0122 0.0122
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.0505 0.0505
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0035 0.0034
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0056 0.0273
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0217 0.0217
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0189 0.0496 0.2699
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0065 0.0142 0.0142
Schistosoma mansoni adenoreceptor 0.0065 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0083 0.0083
Echinococcus multilocularis aldo keto reductase 0.0111 0.0275 0.0275
Echinococcus multilocularis protein jagged 2 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0111 0.0275 0.0371
Loa Loa (eye worm) acetyltransferase 0.0145 0.0371 0.0501
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0065 0.0142 0.0192
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.0097 0.077
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.0097 0.0523
Echinococcus multilocularis histone deacetylase 3 0.0366 0.1001 0.1001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0142 0.0142
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0086 0.0439
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0359 0.0359
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.0097 0.0497
Echinococcus granulosus pyruvate kinase 0.0035 0.0056 0.0056
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0005 0.0006
Echinococcus multilocularis histone deacetylase 0.0131 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0026 0.0032 0.0032
Brugia malayi hypothetical protein 0.014 0.0356 0.048
Schistosoma mansoni neuropeptide receptor 0.0065 0.0142 0.0142
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0111 0.0275 0.1493
Onchocerca volvulus 0.0174 0.0454 0.06
Brugia malayi G protein-coupled receptor 0.0065 0.0142 0.0191
Echinococcus granulosus pyruvate kinase 0.0035 0.0056 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0035 0.0047
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.0279 0.1495
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0045 0.0085 0.0114
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Plasmodium vivax vivapain-1 0.0026 0.0031 0.0307
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Brugia malayi NADH-dependent xylose reductase 0.0045 0.0085 0.0114
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0085 0.04
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0142 0.0142
Toxoplasma gondii aldose reductase, putative 0.0111 0.0275 0.2198
Schistosoma mansoni neuropeptide F-like receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0045 0.0085 0.04
Schistosoma mansoni ATP-binding cassette transporter 0.0064 0.014 0.014
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0031 0.0031
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0065 0.0142 0.0142
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0189 0.0496 0.2699
Brugia malayi nuclear hormone receptor family member nhr-6 0.0051 0.0103 0.0138
Onchocerca volvulus 0.0051 0.0102 0.0124
Onchocerca volvulus 0.0051 0.0103 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Echinococcus multilocularis neuropeptide Y receptor 0.0065 0.0142 0.0142
Schistosoma mansoni ap endonuclease 0.0057 0.0119 0.0119
Brugia malayi Latrophilin receptor protein 2 0.01 0.0242 0.0326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Schistosoma mansoni thyroid hormone receptor 0.0359 0.0982 0.0982
Onchocerca volvulus 0.0099 0.0241 0.0312
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0122 0.0122
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0026 0.0032 0.0169
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0036 0.006 0.0296
Loa Loa (eye worm) G-protein coupled receptor 0.0065 0.0142 0.0192
Loa Loa (eye worm) latrophilin receptor protein 2 0.01 0.0242 0.0327
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0026 0.0032 0.0032
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0093 0.0093
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Echinococcus multilocularis thyroid hormone receptor alpha 0.0359 0.0982 0.0982
Schistosoma mansoni rab6-interacting 0.014 0.0356 0.0356
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Mycobacterium ulcerans epoxide hydrolase EphA 0.0161 0.0415 0.2236
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0009 0.0009
Onchocerca volvulus 0.261 0.7403 1
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0109 0.0267 0.0267
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.01 0.0242 0.0242
Brugia malayi Serotonin receptor 0.0065 0.0142 0.0191
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi notch-like transmembrane receptor 0.0452 0.1246 0.1683
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0036 0.006 0.0296
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0102 0.0136
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0056 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0039 0.0165
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0192 0.0505 0.0683
Schistosoma mansoni hypothetical protein 0.0065 0.0142 0.0142
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0121 0.0162
Loa Loa (eye worm) neuropeptide F receptor 0.0065 0.0142 0.0192
Plasmodium falciparum thioredoxin reductase 0.0017 0.0006 0.005
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.003 0.0158
Onchocerca volvulus 0.0051 0.0102 0.0124
Brugia malayi nuclear receptor NHR-88 0.0051 0.0103 0.0138
Schistosoma mansoni hypothetical protein 0.0036 0.006 0.006
Echinococcus multilocularis neuropeptide s receptor 0.2015 0.5705 0.5705
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0067 0.0533
Schistosoma mansoni aldo-keto reductase 0.0111 0.0275 0.0275
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0006 0.005
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0119 0.1177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0054 0.0241
Onchocerca volvulus 0.006 0.0129 0.016
Echinococcus multilocularis notch 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0036 0.006 0.0296
Echinococcus multilocularis serotonin receptor 0.0065 0.0142 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0035 0.0046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.0505 0.0505
Echinococcus multilocularis NMDA receptor 0.0024 0.0024 0.0024
Entamoeba histolytica hypothetical protein 0.0076 0.0174 0.1514
Loa Loa (eye worm) hypothetical protein 0.0316 0.0858 0.1158
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Trypanosoma brucei trypanothione reductase 0.005 0.0098 0.0531
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0509 0.277
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0131 0.0178
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Schistosoma mansoni hypothetical protein 0.01 0.0242 0.0242
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0079 0.0778
Brugia malayi ORL1-like opioid receptor 0.0065 0.0142 0.0191
Plasmodium falciparum glutathione reductase 0.005 0.0098 0.0973
Giardia lamblia Pyruvate kinase 0.0035 0.0056 0.0405
Schistosoma mansoni organic anion transporter 0.0027 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0131 0.0331 0.0447
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0056 0.0252
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0658 0.1835 1
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0026 0.0032 0.0309
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.0505 0.0505
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Onchocerca volvulus Peroxidasin homolog 0.261 0.7403 1
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0036 0.006 0.0296
Echinococcus multilocularis histone deacetylase 6 0.0131 0.0331 0.0331
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Schistosoma mansoni neuropeptide F-like receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis cathepsin L 0.0026 0.0031 0.0031
Leishmania major p450 reductase, putative 0.0026 0.0032 0.0169
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.068 0.0919
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0177 0.0461 0.2508
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0072 0.0388
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0275 0.135
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0083 0.0083
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0103 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0109 0.0267 0.0361
Echinococcus multilocularis somatostatin receptor 0.0065 0.0142 0.0142
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0658 0.1835 1
Plasmodium falciparum aldehyde reductase, putative 0.0045 0.0085 0.0846
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0068 0.0435
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0028 0.011
Schistosoma mansoni opsin-like receptor 0.0065 0.0142 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0036 0.006 0.0296
Echinococcus multilocularis aldo keto reductase 0.0111 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Echinococcus granulosus L aminoadipate semialdehyde 0.0174 0.0454 0.0454
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0036 0.006 0.0296
Echinococcus granulosus pyruvate kinase 0.0018 0.0008 0.0008
Schistosoma mansoni lamin 0.0114 0.0281 0.0281
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0122 0.0122
Brugia malayi prostaglandin transporter 0.0027 0.0035 0.0046
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0005 0.0005
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Brugia malayi Glutamate receptor 2 precursor 0.0064 0.014 0.0187
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0072 0.0388
Entamoeba histolytica histone deacetylase, putative 0.0366 0.1001 1
Onchocerca volvulus Neurogenic locus notch homolog 0.0452 0.1247 0.1672
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0016 0.0055
Echinococcus multilocularis histone deacetylase 6 0.0131 0.0331 0.0331
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Trypanosoma cruzi aldo-keto reductase 0.0111 0.0275 0.1493
Echinococcus granulosus Polycystic kidney disease protein 0.014 0.0356 0.0356
Giardia lamblia Hypothetical protein 0.0023 0.0023 0.014
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Onchocerca volvulus 0.0065 0.0142 0.0179
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0026 0.0032 0.0169
Onchocerca volvulus 0.0452 0.1246 0.1672
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0452 0.1246 0.1672
Schistosoma mansoni hypothetical protein 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0044 0.0081 0.0096
Giardia lamblia Aldose reductase 0.0111 0.0275 0.2167
Schistosoma mansoni tyrosine kinase 0.0047 0.009 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0366 0.1001 0.4998
Echinococcus granulosus neurogenic locus notch protein 4 0.0452 0.1246 0.1246
Echinococcus multilocularis histone deacetylase 6 0.0131 0.0331 0.0331
Echinococcus multilocularis ecdysone induced protein 78C 0.0109 0.0267 0.0267
Brugia malayi hypothetical protein 0.014 0.0356 0.048
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0109 0.0267 0.0267
Brugia malayi cytoplasmic intermediate filament protein 0.0061 0.013 0.0175
Schistosoma mansoni hypothetical protein 0.0346 0.0945 0.0945
Echinococcus granulosus phd:f box containing protein 0.0015 0.0001 0.0001
Echinococcus multilocularis glutamate receptor 2 0.0064 0.014 0.014
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0036 0.006 0.0296
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0001 0.0001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0006 0.0027
Brugia malayi latrophilin 2 splice variant baaae 0.0216 0.0573 0.0772
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0005 0.0022
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0006
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0073
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Brugia malayi jmjC domain containing protein 0.0061 0.0131 0.0176
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Plasmodium vivax vivapain-3 0.0026 0.0031 0.0307
Schistosoma mansoni tyrosine kinase 0.0079 0.0181 0.0181
Echinococcus granulosus histone deacetylase 7 0.0131 0.0331 0.0331
Trypanosoma cruzi aldo/keto reductase, putative 0.0045 0.0085 0.0462
Onchocerca volvulus 0.014 0.0356 0.0468
Echinococcus granulosus histone deacetylase 0.0131 0.0331 0.0331
Echinococcus granulosus histone deacetylase 6 0.0131 0.0331 0.0331
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0035 0.0035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.001 0.0013
Schistosoma mansoni cell polarity protein 0.0452 0.1246 0.1246
Schistosoma mansoni cytochrome P450 reductase 0.0026 0.0032 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0044 0.0235
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Leishmania major cytochrome P450 reductase, putative 0.0023 0.0023 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0095
Echinococcus multilocularis g-protein coupled receptor 0.0065 0.0142 0.0142
Brugia malayi Doublecortin family protein 0.014 0.0356 0.048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0086 0.0465
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.0014
Leishmania major prostaglandin f synthase, putative 0.0111 0.0275 0.1493
Echinococcus multilocularis fibropellin Ia 0.0452 0.1246 0.1246
Onchocerca volvulus 0.0096 0.0231 0.0298
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Schistosoma mansoni glutamate receptor kainate 0.0064 0.014 0.014
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3429 0.9739 0.9739
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0068 0.0505
Trypanosoma brucei histone deacetylase, putative 0.0131 0.0331 0.1801
Schistosoma mansoni biogenic amine (5HT) receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0083 0.0386
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.0315 0.8615
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0174 0.0174
Plasmodium vivax flavodoxin domain containing protein 0.0023 0.0023 0.0224
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0098 0.0973
Echinococcus granulosus orexin receptor type 2 0.0065 0.0142 0.0142
Plasmodium falciparum histone deacetylase 2 0.0131 0.0331 0.3303
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0031 0.0167
Plasmodium vivax SET domain protein, putative 0.0091 0.0217 0.2164
Echinococcus granulosus neurogenic locus notch protein 0.0452 0.1246 0.1246
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0001 0.0001
Echinococcus granulosus methionine synthase reductase 0.0016 0.0003 0.0003
Plasmodium vivax vivapain-2 0.0051 0.0102 0.1009
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0275 0.135
Onchocerca volvulus 0.0109 0.0267 0.0347
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0001 0.0001
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.068 0.0918
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0102 0.0102
Echinococcus multilocularis fatty acid binding protein FABP2 0.0034 0.0054 0.0054
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0119 0.0119
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.0097 0.118
Echinococcus multilocularis pyruvate kinase 0.0035 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.016 0.0414 0.0559
Schistosoma mansoni glutamate receptor kainate 0.0064 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Brugia malayi putative neuropeptide receptor 0.0065 0.0142 0.0191
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0102 0.055
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Onchocerca volvulus 0.0051 0.0102 0.0124
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Schistosoma mansoni P2X receptor subunit 0.0229 0.0611 0.0611
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0058 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.0505 0.0505
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0102 0.0124
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0031 0.0167
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0098 0.0098
Echinococcus granulosus tachykinin peptides receptor 99D 0.0065 0.0142 0.0142
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0119 0.016
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0085 0.04
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0109 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Echinococcus granulosus agrin 0.0019 0.001 0.001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0192 0.0505 0.0682
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0044 0.0082 0.0414
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0032 0.0169
Echinococcus granulosus hypothetical protein 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Echinococcus granulosus epidermal growth factor receptor 0.0079 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0098 0.0505
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Schistosoma mansoni P2X receptor subunit 0.0229 0.0611 0.0611
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0065 0.0142 0.0142
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0001 0.0001
Echinococcus granulosus nmda type glutamate receptor 0.0138 0.0351 0.0351
Echinococcus multilocularis neuropeptide FF receptor 2 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0065 0.0142 0.0179
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0053 0.0287
Echinococcus granulosus cathepsin L 0.0026 0.0031 0.0031
Echinococcus granulosus notch 0.0452 0.1246 0.1246
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0001 0.0001
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0072 0.0332
Onchocerca volvulus Peroxidasin homolog 0.261 0.7403 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0056 0.0075
Onchocerca volvulus 0.0051 0.0102 0.0124
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.1299 0.1299
Plasmodium falciparum nitric oxide synthase, putative 0.0026 0.0032 0.0309
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Echinococcus multilocularis geminin 0.0346 0.0945 0.0945
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Echinococcus granulosus biogenic amine 5HT receptor 0.0065 0.0142 0.0142
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0142 0.0142
Echinococcus granulosus p2X purinoceptor 4 0.0536 0.1485 0.1485
Echinococcus multilocularis neuropeptide receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0076 0.0174 0.0174
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0119 0.1177
Giardia lamblia DINP protein human, muc B family 0.0021 0.0016 0.0081
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Echinococcus multilocularis dna polymerase kappa 0.004 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0427 0.1174 0.1174
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0014
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Plasmodium vivax histone deacetylase 1, putative 0.0366 0.1001 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0083 0.0111
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Onchocerca volvulus Peroxidase homolog 0.261 0.7403 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0316 0.0858 0.1157
Loa Loa (eye worm) notch protein 0.0452 0.1246 0.1683
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Plasmodium falciparum LCCL domain-containing protein 0.014 0.0356 0.3551
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0056 0.0062
Leishmania major cysteine peptidase A (CPA) 0.0051 0.0102 0.055
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0065 0.0142 0.0179
Schistosoma mansoni agrin 0.0019 0.001 0.001
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0031 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0096
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0102 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0014
Brugia malayi flavodoxin family protein 0.0026 0.0032 0.0042
Brugia malayi hypothetical protein 0.261 0.7403 1
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0044 0.0082 0.0109
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0031 0.0167
Echinococcus granulosus glutamate receptor 2 0.0076 0.0174 0.0174
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0072 0.0361
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0217 0.0217
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0119 0.0908
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0119 0.0948
Schistosoma mansoni cytochrome P450 0.0036 0.006 0.006
Brugia malayi intermediate filament protein 0.0114 0.0281 0.0378
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0056 0.0062
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Echinococcus granulosus cathepsin l cysteine peptidase 0.0051 0.0102 0.0102
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Loa Loa (eye worm) animal heme peroxidase 0.261 0.7403 1
Echinococcus multilocularis pyruvate kinase 0.0018 0.0008 0.0008
Brugia malayi nuclear hormone receptor 0.0109 0.0267 0.036
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Schistosoma mansoni cpg binding protein 0.0064 0.0139 0.0139
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0065 0.0142 0.0192
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0016 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Loa Loa (eye worm) inositol-1 0.0039 0.0067 0.0091
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0036 0.006 0.0296
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0006 0.0292
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Schistosoma mansoni aldo-keto reductase 0.0111 0.0275 0.0275
Onchocerca volvulus 0.0111 0.0275 0.0358
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0119 0.0642
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Plasmodium falciparum glutathione reductase 0.0017 0.0006 0.005
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Leishmania major trypanothione reductase 0.005 0.0098 0.0531
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0119 0.0642
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0065 0.0142 0.0142
Echinococcus granulosus neural cadherin 0.0452 0.1246 0.1246
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.003 0.0158
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0119 0.1464
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0099 0.0241 0.0312
Brugia malayi Furin-like cysteine rich region family protein 0.0146 0.0375 0.0505
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0109 0.0267 0.0267
Onchocerca volvulus 0.0065 0.0142 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0064 0.0294
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0044 0.0082 0.0414
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0109 0.0267 0.036
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0051 0.0103 0.0138
Echinococcus granulosus FTZ F1 alpha 0.0109 0.0267 0.0267
Schistosoma mansoni neuropeptide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0065 0.0142 0.0142
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0026 0.0032 0.0169
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0187 0.0491 0.065
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0055 0.0113 0.0113
Mycobacterium ulcerans glyoxalase GloA 0.0044 0.0082 0.0414
Brugia malayi ecdysteroid receptor 0.0109 0.0267 0.036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0109 0.0267 0.036
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0045 0.0085 0.068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Echinococcus multilocularis pyruvate kinase 0.0035 0.0056 0.0056
Echinococcus multilocularis allatostatin A receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis fatty acid binding protein FABP2 0.0034 0.0054 0.0054
Schistosoma mansoni histone deacetylase 1 2 3 0.0131 0.0331 0.0331
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0019 0.0024
Giardia lamblia Pyruvate kinase 0.0018 0.0008 0.0016
Schistosoma mansoni histone deacetylase 4 5 0.0131 0.0331 0.0331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Plasmodium falciparum glyoxalase I 0.0189 0.0496 0.495
Loa Loa (eye worm) cytochrome P450 family protein 0.0075 0.017 0.023
Echinococcus granulosus 7tm_1 domain containing protein 0.0065 0.0142 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0032 0.0132
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0065 0.0142 0.0142
Mycobacterium leprae putative cytochrome p450 0.0036 0.006 0.0145
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0056 0.0076
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.0097 0.8064
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0452 0.1246 0.1683
Echinococcus multilocularis neuropeptide receptor 0.0065 0.0142 0.0142
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0109 0.0267 0.0267
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0008 0.007
Echinococcus granulosus lamin 0.0114 0.0281 0.0281
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0217 0.0217
Loa Loa (eye worm) fibroinase 0.0051 0.0102 0.0137
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0006 0.0007
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0209 0.0209
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0142 0.0142
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0045 0.0085 0.0462
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0098 0.0531
Echinococcus granulosus histone deacetylase 6 0.0131 0.0331 0.0331
Echinococcus granulosus p2X purinoceptor 4 0.0536 0.1485 0.1485
Onchocerca volvulus 0.0065 0.0142 0.0179
Schistosoma mansoni hypothetical protein 0.01 0.0242 0.0242
Schistosoma mansoni hypothetical protein 0.01 0.0242 0.0242
Schistosoma mansoni growth hormone secretagogue receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Onchocerca volvulus 0.0051 0.0102 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0109 0.0267 0.0361
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Brugia malayi polk-prov protein 0.0031 0.0044 0.0058
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0051 0.0103 0.0103
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0019 0.0026
Onchocerca volvulus 0.0035 0.0058 0.0064
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0275 0.037
Brugia malayi Blistered cuticle protein 3 0.261 0.7403 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0275 0.0371
Schistosoma mansoni myosin xvIII 0.0065 0.0142 0.0142
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0024 0.0024 0.0024
Onchocerca volvulus 0.261 0.7403 1
Schistosoma mansoni intermediate filament proteins 0.0114 0.0281 0.0281
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0065 0.0142 0.0192
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Onchocerca volvulus 0.014 0.0356 0.0468
Echinococcus granulosus neurogenic locus protein delta 0.0452 0.1246 0.1246
Brugia malayi Pre-SET motif family protein 0.0629 0.175 0.2363
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Echinococcus granulosus fatty acid binding protein FABP2 0.0034 0.0054 0.0054
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0098 0.0098
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0209 0.0209
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0629 0.175 0.2364
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0096
Schistosoma mansoni laminin gamma-3 chain 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0006
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0129 0.0174
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0189 0.0496 0.0657
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus multilocularis p2X purinoceptor 4 0.0536 0.1485 0.1485
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0109 0.0267 0.0267
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0072 0.0388
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0009 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0036 0.006 0.0296
Echinococcus multilocularis lipoxygenase domain containing protein 0.014 0.0356 0.0356
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.001 0.0019
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0054 0.0285
Schistosoma mansoni hypothetical protein 0.014 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0095
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0072 0.0388
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0036 0.006 0.0296
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.0279 0.1495
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0109 0.0267 0.036
Schistosoma mansoni glutamate receptor AMPA 0.0064 0.014 0.014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0009 0.0009
Echinococcus multilocularis glutamate receptor 2 0.0076 0.0174 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0036 0.006 0.0296
Echinococcus granulosus follistatin 0.0019 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0031 0.0128
Echinococcus multilocularis orexin receptor type 2 0.0065 0.0142 0.0142
Leishmania major pyruvate kinase 0.0035 0.0056 0.0302
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0056 0.0553
Schistosoma mansoni hypothetical protein 0.0346 0.0945 0.0945
Echinococcus granulosus neuropeptide receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0044 0.0081 0.0412
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus multilocularis cysteine protease 0.0051 0.0102 0.0102
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0471 0.1299 0.1755
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0067 0.0067
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0083 0.0386
Echinococcus multilocularis histone deacetylase 8 0.0131 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Echinococcus multilocularis cpg binding protein 0.0064 0.0139 0.0139
Echinococcus granulosus single minded 2 0.0035 0.0058 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0044 0.0235
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0068 0.0676
Onchocerca volvulus 0.0715 0.1998 0.2688
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0036 0.006 0.0323
Schistosoma mansoni tyrosine kinase 0.0079 0.0181 0.0181
Schistosoma mansoni gynecophoral canal protein 0.0044 0.0082 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0109 0.0267 0.0361
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.0097 0.0497
Giardia lamblia Aldose reductase 0.0111 0.0275 0.2167
Onchocerca volvulus Cathepsin F homolog 0.0051 0.0102 0.0124
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0028 0.011
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0079 0.0079
Echinococcus multilocularis voltage gated potassium channel subunit 0.0045 0.0085 0.0085
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Brugia malayi Calcium binding EGF domain containing protein 0.0452 0.1246 0.1683
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Brugia malayi Inositol-1 0.0039 0.0067 0.009
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0072 0.0388
Brugia malayi Intermediate filament tail domain containing protein 0.0114 0.0281 0.0378
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0023 0.0023 0.0087
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0031 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0121 0.0162
Brugia malayi Nuclear hormone receptor E75 0.0051 0.0103 0.0138
Loa Loa (eye worm) TYRA-2 protein 0.0065 0.0142 0.0192
Echinococcus granulosus peroxidasin 0.261 0.7403 0.7403
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0034 0.0054 0.0071
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0097 0.0523
Brugia malayi Calcium binding EGF domain containing protein 0.0452 0.1246 0.1683
Mycobacterium leprae Possible oxidoreductase 0.0045 0.0085 0.0989
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0035 0.0274
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0379 0.0512
Trichomonas vaginalis sulfite reductase, putative 0.0026 0.0032 0.013
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0036 0.006 0.0296
Echinococcus granulosus protein jagged 2 0.0452 0.1246 0.1246
Echinococcus granulosus neuropeptide s receptor 0.2015 0.5705 0.5705
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Leishmania major histone deacetylase, putative 0.0366 0.1001 0.5454
Loa Loa (eye worm) oxidoreductase 0.0044 0.0081 0.011
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0086 0.0465
Brugia malayi Cadherin domain containing protein 0.0452 0.1246 0.1683
Echinococcus multilocularis protein jagged 1 0.0452 0.1246 0.1246
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0047 0.009 0.009
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0065 0.0142 0.0142
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0006 0.0027
Onchocerca volvulus 0.0044 0.0081 0.0096
Onchocerca volvulus 0.0065 0.0142 0.0179
Leishmania major cytochrome p450-like protein 0.0036 0.006 0.0323
Toxoplasma gondii histone deacetylase HDAC3 0.0366 0.1001 0.8032
Echinococcus multilocularis L aminoadipate semialdehyde 0.0174 0.0454 0.0454
Schistosoma mansoni nuclear receptor nhr-48 0.0051 0.0103 0.0103
Echinococcus multilocularis neurogenic locus notch protein 4 0.0452 0.1246 0.1246
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0031 0.0031
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0005 0.0022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0109 0.0267 0.0267
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0006 0.004
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0014
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0086 0.0116
Schistosoma mansoni cpg binding protein 0.0064 0.0139 0.0139
Schistosoma mansoni hypothetical protein 0.0076 0.0174 0.0174
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Loa Loa (eye worm) hypothetical protein 0.0053 0.0107 0.0145
Schistosoma mansoni histamine h1 receptor 0.0065 0.0142 0.0142
Brugia malayi Serotonin receptor 0.0065 0.0142 0.0191
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Echinococcus granulosus neurogenic locus notch protein 0.0452 0.1246 0.1246
Brugia malayi hypoxia-induced factor 1 0.0148 0.0379 0.0511
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0097 0.0959
Brugia malayi cytochrome P450 0.0036 0.006 0.008
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0109 0.0267 0.0347
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0142 0.0142
Schistosoma mansoni single-minded 0.0048 0.0093 0.0093
Onchocerca volvulus Protein ultraspiracle homolog 0.0109 0.0267 0.0347
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0072 0.0388
Entamoeba histolytica hypothetical protein 0.0076 0.0174 0.1514
Loa Loa (eye worm) histone deacetylase 7A 0.0131 0.0331 0.0447
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Brugia malayi GnHR receptor homolog 0.0065 0.0142 0.0191
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0057 0.0121 0.0121
Loa Loa (eye worm) FAD binding domain-containing protein 0.0026 0.0032 0.0043
Brugia malayi hypothetical protein 0.0027 0.0035 0.0046
Plasmodium vivax unspecified product 0.0017 0.0005 0.0039
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0026 0.0035
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.0279 0.7421
Brugia malayi Cadherin domain containing protein 0.0452 0.1246 0.1683
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0009 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0109 0.0267 0.0267
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.0097 0.0497
Brugia malayi dehydrogenases, short chain protein 2 0.0044 0.0081 0.0109
Schistosoma mansoni fatty acid binding protein 0.0034 0.0054 0.0054
Echinococcus multilocularis glutamate receptor 2 0.0053 0.0107 0.0107
Echinococcus multilocularis expressed protein 0.0019 0.001 0.001
Echinococcus multilocularis pyruvate kinase 0.0027 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0076 0.0174 0.0174
Loa Loa (eye worm) cysteine protease 0.0051 0.0102 0.0137
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0044 0.0081 0.0096
Brugia malayi Cathepsin L-like precursor 0.0051 0.0102 0.0136
Echinococcus granulosus G protein coupled receptor 139 0.0065 0.0142 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0109 0.0267 0.036
Onchocerca volvulus 0.0452 0.1246 0.1672
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0024 0.0024 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Echinococcus granulosus nuclear receptor nhr 48 0.0051 0.0103 0.0103
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0026 0.0032 0.0142
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0083 0.0447
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0024 0.0024 0.0024
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0658 0.1835 1
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Schistosoma mansoni P2X receptor subunit 0.0536 0.1485 0.1485
Brugia malayi FAD binding domain containing protein 0.0026 0.0032 0.0042
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0362
Echinococcus granulosus glutamate NMDA receptor subunit 0.0152 0.0391 0.0391
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0057 0.0257
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Schistosoma mansoni histone deacetylase 4 5 0.0131 0.0331 0.0331
Onchocerca volvulus Neuropeptide F receptor homolog 0.0065 0.0142 0.0179
Echinococcus multilocularis glutamate receptor NMDA 0.0126 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Onchocerca volvulus Bile acid receptor homolog 0.0109 0.0267 0.0347
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0776 0.7689
Echinococcus multilocularis neurogenic locus notch protein 0.0452 0.1246 0.1246
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0837 0.2345 0.2345
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0036 0.006 0.0296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0045 0.0085 0.068
Onchocerca volvulus Putative protein 0.0044 0.0082 0.0097
Onchocerca volvulus 0.0051 0.0102 0.0124
Echinococcus multilocularis histone deacetylase 7 0.0131 0.0331 0.0331
Schistosoma mansoni biogenic amine (5HT) receptor 0.0065 0.0142 0.0142
Entamoeba histolytica alcohol dehydrogenase, putative 0.0045 0.0085 0.0609
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Leishmania major cathepsin L-like protease 0.0193 0.0509 0.277
Onchocerca volvulus 0.0027 0.0035 0.0034
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0032 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0275 0.135
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0251 0.0672 0.0672
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0036 0.006 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0032 0.0132
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Echinococcus granulosus nmda type glutamate receptor 0.015 0.0384 0.0384
Echinococcus multilocularis epidermal growth factor receptor 0.0079 0.0181 0.0181
Echinococcus multilocularis insulin receptor 0.0047 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Echinococcus granulosus thyroid hormone receptor alpha 0.0051 0.0103 0.0103
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0067 0.545
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0357 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0065 0.0142 0.0142
Echinococcus granulosus Solute carrier family 22 5 0.2033 0.5758 0.5758
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0103 0.0103
Mycobacterium leprae Conserved hypothetical protein 0.0066 0.0146 0.2999
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0275 0.037
Onchocerca volvulus 0.0065 0.0142 0.0179
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0036 0.006 0.0296
Brugia malayi SPARC precursor 0.0019 0.001 0.0013
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0083 0.0447
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0057 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0026 0.0032 0.0032
Onchocerca volvulus 0.0111 0.0275 0.0358
Echinococcus granulosus dna polymerase kappa 0.004 0.0072 0.0072
Leishmania major histone deacetylase, putative 0.0366 0.1001 0.5454
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0065 0.0142 0.0142
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0031 0.0307
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0032 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus multilocularis cysteine protease 0.0051 0.0102 0.0102
Echinococcus multilocularis serotonin receptor 0.0065 0.0142 0.0142
Entamoeba histolytica aldose reductase, putative 0.0111 0.0275 0.2549
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Brugia malayi hypothetical protein 0.0026 0.003 0.0039
Schistosoma mansoni hypothetical protein 0.01 0.0242 0.0242
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Entamoeba histolytica aldose reductase, putative 0.0111 0.0275 0.2549
Brugia malayi hypothetical protein 0.0471 0.1299 0.1754
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0032 0.0169
Schistosoma mansoni hypothetical protein 0.0065 0.0142 0.0142
Schistosoma mansoni septate junction protein 0.0452 0.1246 0.1246
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0206 0.0543 0.0543
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0251 0.0672 0.0672
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0357 0.1919
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0316 0.0858 0.1157
Brugia malayi orphan nuclear receptor NR2E1 0.0051 0.0103 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0082 0.0381
Brugia malayi tailless protein 0.0051 0.0103 0.0138
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus multilocularis pyruvate kinase 0.0018 0.0008 0.0008
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Trypanosoma brucei histone deacetylase 2 0.0131 0.0331 0.1801
Echinococcus multilocularis dnaJ subfamily B 0.0427 0.1174 0.1174
Schistosoma mansoni nuclear hormone receptor 0.0109 0.0267 0.0267
Schistosoma mansoni hypothetical protein 0.0452 0.1246 0.1246
Trypanosoma cruzi histone deacetylase 1, putative 0.0366 0.1001 0.5454
Loa Loa (eye worm) histone deacetylase 3 0.0366 0.1001 0.1352
Trypanosoma cruzi aldo/keto reductase, putative 0.0111 0.0275 0.1493
Echinococcus multilocularis aldo keto reductase 0.0111 0.0275 0.0275
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0026 0.0032 0.0032
Echinococcus granulosus somatostatin receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0067 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.001 0.0019
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0119 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0011 0.0011
Schistosoma mansoni nuclear receptor 0.0051 0.0103 0.0103
Onchocerca volvulus 0.0044 0.0081 0.0096
Brugia malayi cathepsin L-like precursor 0.0034 0.0054 0.0072
Brugia malayi Cathepsin L-like precursor 0.0034 0.0054 0.0072
Plasmodium falciparum histone deacetylase, putative 0.0131 0.0331 0.3303
Onchocerca volvulus 0.0051 0.0102 0.0124
Echinococcus granulosus epidermal growth factor receptor 0.0146 0.0375 0.0375
Echinococcus multilocularis aldehyde reductase 0.0066 0.0146 0.0146
Brugia malayi nuclear receptor RXR 0.0057 0.0121 0.0162
Plasmodium vivax aldehyde reductase, putative 0.0045 0.0085 0.0846
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0036 0.006 0.0296
Brugia malayi histone deacetylase 11 0.0131 0.0331 0.0446
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0065 0.0142 0.0192
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0024 0.0024 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0032 0.0132
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0036 0.006 0.0296
Onchocerca volvulus Phospholipase A2 homolog 0.0185 0.0485 0.0643
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0275 0.0275
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0051 0.0103 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0083 0.0386
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0086 0.0465
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0119 0.0642
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0119 0.0119
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0075
Echinococcus granulosus fmrfamide receptor 0.0065 0.0142 0.0142
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0109 0.0267 0.0267
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.068 0.3388
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0109 0.0267 0.036
Schistosoma mansoni RAR-like nuclear receptor 0.0109 0.0267 0.0267
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0045 0.0085 0.0115
Schistosoma mansoni tyrosine kinase 0.0146 0.0375 0.0375
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0119 0.0566
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.001 0.0013
Schistosoma mansoni survival motor neuron protein 0.0096 0.0231 0.0231
Toxoplasma gondii protease inhibitor PI2 0.0019 0.001 0.0075
Brugia malayi Melatonin receptor type 1A 0.0065 0.0142 0.0191
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0036 0.006 0.0296
Brugia malayi Nuclear hormone receptor E75 0.0051 0.0103 0.0138
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0001 0.0001
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0658 0.1835 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.001 0.0013
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0366 0.1001 0.4998
Loa Loa (eye worm) nuclear hormone receptor 0.0051 0.0103 0.0139
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0142 0.0142
Schistosoma mansoni pyruvate kinase 0.0035 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0096 0.0231 0.0231
Brugia malayi putative neuropeptide receptor NPR1 0.0065 0.0142 0.0191
Onchocerca volvulus 0.0065 0.0142 0.0179
Schistosoma mansoni slit 0.0452 0.1246 0.1246
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0161 0.0415 0.2236
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0096
Loa Loa (eye worm) nuclear receptor NHR-67 0.0051 0.0103 0.0139
Loa Loa (eye worm) hypothetical protein 0.0053 0.0107 0.0145
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0109 0.0267 0.0361
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0001 0.0001
Schistosoma mansoni P2X receptor subunit 0.0536 0.1485 0.1485
Loa Loa (eye worm) G-protein coupled receptor 0.0065 0.0142 0.0192
Loa Loa (eye worm) cytochrome P450 0.0036 0.006 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0142 0.0142
Leishmania major DNA polymerase kappa, putative 0.0021 0.0016 0.0082
Onchocerca volvulus 0.0452 0.1246 0.1672
Schistosoma mansoni tyrosine kinase 0.0047 0.009 0.009
Mycobacterium leprae conserved hypothetical protein 0.0044 0.0082 0.0861
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0036 0.006 0.0296
Echinococcus granulosus aldo keto reductase 0.0111 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0109 0.0267 0.036
Echinococcus multilocularis musashi 0.0114 0.0281 0.0281
Brugia malayi jmjC domain containing protein 0.0058 0.0122 0.0163
Echinococcus multilocularis GPCR, family 2 0.01 0.0242 0.0242
Onchocerca volvulus Histone deacetylase 10 homolog 0.0131 0.0331 0.0434
Echinococcus multilocularis nmda type glutamate receptor 0.015 0.0384 0.0384
Echinococcus granulosus peptide allatostatin:somatostatin 0.0065 0.0142 0.0142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0357 0.1919
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0051 0.0103 0.0126
Onchocerca volvulus 0.0027 0.0035 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Brugia malayi hypothetical protein 0.0051 0.0103 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0051 0.0224
Toxoplasma gondii glyoxalase I, putative 0.0189 0.0496 0.3975
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0837 0.2345 0.2345
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0036 0.006 0.0296
Brugia malayi SET domain containing protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Schistosoma mansoni lipoxygenase 0.0585 0.1626 0.1626
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Brugia malayi Animal haem peroxidase family protein 0.261 0.7403 1
Schistosoma mansoni thyroid hormone receptor 0.0359 0.0982 0.0982
Onchocerca volvulus Dual oxidase homolog 0.261 0.7403 1
Schistosoma mansoni pyruvate kinase 0.0035 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.01 0.0242 0.0327
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0114 0.0281 0.0379
Schistosoma mansoni peroxidasin 0.261 0.7403 0.7403
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0085 0.04
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0086 0.0116
Echinococcus granulosus p2X purinoceptor 4 0.0536 0.1485 0.1485
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Schistosoma mansoni histone deacetylase hda2 0.0131 0.0331 0.0331
Echinococcus granulosus aldo keto reductase 0.0111 0.0275 0.0275
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.0315 0.1691
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0067 0.0308
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0051 0.0103 0.0103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0102 0.0482
Echinococcus granulosus aldo keto reductase 0.0111 0.0275 0.0275
Echinococcus granulosus biogenic amine 5HT receptor 0.0065 0.0142 0.0142
Brugia malayi nuclear receptor NHR-67 0.0051 0.0103 0.0138
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0057 0.0307
Chlamydia trachomatis pyruvate kinase 0.0035 0.0056 0.5663
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0067 0.0422
Onchocerca volvulus 0.0044 0.0081 0.0096
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0065 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0109 0.0267 0.036
Loa Loa (eye worm) doublecortin family protein 0.014 0.0356 0.0481
Schistosoma mansoni peroxidasin 0.261 0.7403 0.7403
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.01 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0061 0.013 0.0176
Brugia malayi hypothetical protein 0.0044 0.0081 0.0109
Toxoplasma gondii histone deacetylase HDAC1 0.0131 0.0331 0.2653
Loa Loa (eye worm) hypothetical protein 0.014 0.0356 0.0481
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Schistosoma mansoni follistatin 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Onchocerca volvulus 0.0044 0.0081 0.0096
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0036 0.006 0.0296
Trypanosoma brucei unspecified product 0.0034 0.0053 0.0287
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0119 0.0616
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0027
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0109 0.0267 0.0361
Onchocerca volvulus 0.0051 0.0103 0.0126
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0131 0.0131
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0056 0.0444
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Leishmania major hypothetical protein, conserved 0.0026 0.003 0.0158
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0035 0.0035
Loa Loa (eye worm) glutathione reductase 0.005 0.0098 0.0133
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0001 0.0001
Echinococcus multilocularis neural cadherin 0.0452 0.1246 0.1246
Schistosoma mansoni tyrosine kinase 0.0078 0.0179 0.0179
Plasmodium falciparum aldo-keto reductase, putative 0.0045 0.0085 0.0846
Brugia malayi G-protein coupled receptor 0.0065 0.0142 0.0191
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0072 0.0361
Entamoeba histolytica alcohol dehydrogenase, putative 0.0045 0.0085 0.0609
Schistosoma mansoni ap endonuclease 0.0057 0.0119 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0109 0.0267 0.0361
Onchocerca volvulus 0.0111 0.0275 0.0358
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Brugia malayi histone deacetylase 1 (HD1) 0.0366 0.1001 0.1351
Echinococcus multilocularis fat cadherin tumor suppressor 0.0452 0.1246 0.1246
Schistosoma mansoni neuropeptide receptor 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0045 0.0085 0.0102
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0047
Schistosoma mansoni organic anion transporter 0.0027 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0073
Brugia malayi hypothetical protein 0.0076 0.0174 0.0234
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0075
Schistosoma mansoni inositol monophosphatase 0.0039 0.0067 0.0067
Toxoplasma gondii aldo-keto reductase 0.0045 0.0085 0.068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0031 0.0129
Echinococcus granulosus lipoxygenase domain containing protein 0.014 0.0356 0.0356
Brugia malayi CXXC zinc finger family protein 0.006 0.0129 0.0173
Schistosoma mansoni amine GPCR 0.0065 0.0142 0.0142
Onchocerca volvulus 0.0027 0.0035 0.0034
Toxoplasma gondii cathepsin CPL 0.0051 0.0102 0.081
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.003 0.029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0509 0.277
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0024 0.0024 0.0024
Loa Loa (eye worm) oxidoreductase 0.0111 0.0275 0.0371
Echinococcus multilocularis neurogenic locus notch protein 0.0452 0.1246 0.1246
Echinococcus granulosus g protein coupled receptor 0.0065 0.0142 0.0142
Loa Loa (eye worm) neuropeptide F receptor 0.0065 0.0142 0.0192
Schistosoma mansoni retinoic acid receptor RXR 0.0206 0.0543 0.0543
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0006 0.0027
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0081 0.0109
Schistosoma mansoni opsin-like receptor 0.0065 0.0142 0.0142
Echinococcus granulosus 7TM GPCR rhodopsin 0.0065 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0065 0.0142 0.0142
Echinococcus multilocularis p2X purinoceptor 4 0.0536 0.1485 0.1485
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0057 0.0307
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0111 0.0275 0.7268
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0001 0.0001
Loa Loa (eye worm) steroid hormone receptor 0.0109 0.0267 0.0361
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0056 0.0302
Trypanosoma brucei aldo-keto reductase, putative 0.0111 0.0275 0.1493
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0102 0.0482
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0031 0.0167
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0024 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0109 0.0267 0.036
Brugia malayi Glutamate receptor 1 precursor 0.0064 0.014 0.0187
Trypanosoma cruzi major cysteine proteinase, putative 0.0152 0.0391 0.2125
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0658 0.1835 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.0505 0.0505
Echinococcus granulosus neuropeptide Y receptor 0.0065 0.0142 0.0142
Mycobacterium ulcerans short chain dehydrogenase 0.0044 0.0081 0.0412
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0119 0.0642
Loa Loa (eye worm) histone deacetylase 0.0131 0.0331 0.0447
Echinococcus granulosus hypothetical protein 0.0111 0.0275 0.0275
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0076 0.0174 0.0174
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0051 0.0399
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0003 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0036 0.006 0.0296
Onchocerca volvulus 0.0065 0.0142 0.0179
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0362
Onchocerca volvulus 0.0065 0.0142 0.0179
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0079 0.0181 0.0181
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0079 0.0625
Echinococcus multilocularis p2X purinoceptor 4 0.0536 0.1485 0.1485
Echinococcus multilocularis nmda type glutamate receptor 0.0138 0.0351 0.0351
Plasmodium falciparum pyruvate kinase 0.0035 0.0056 0.0553
Toxoplasma gondii exonuclease III APE 0.0057 0.0119 0.0945
Giardia lamblia Nitric oxide synthase, inducible 0.0023 0.0023 0.014
Schistosoma mansoni potassium channel beta 0.0045 0.0085 0.0085
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Echinococcus multilocularis slit 2 protein 0.0452 0.1246 0.1246
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0111 0.0275 0.1493
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0085 0.04
Brugia malayi Delta serrate ligand family protein 0.0452 0.1246 0.1683
Echinococcus multilocularis agrin 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0452 0.1246 0.1683
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0051 0.0103 0.0139
Onchocerca volvulus Chorion peroxidase homolog 0.261 0.7403 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0275 0.135
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Echinococcus granulosus g protein coupled receptor 0.0065 0.0142 0.0142
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0142 0.0142
Echinococcus multilocularis nuclear receptor nhr 48 0.0051 0.0103 0.0103
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0776 0.3866
Echinococcus granulosus protein jagged 1 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0163
Schistosoma mansoni notch 0.0452 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0036 0.006 0.0296
Echinococcus granulosus histone deacetylase 8 0.0131 0.0331 0.0331
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0457 0.2267
Brugia malayi hypothetical protein 0.0057 0.0121 0.0162
Brugia malayi EGF-like domain containing protein 0.0452 0.1246 0.1683
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0045 0.0085 0.0846
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0006 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0028 0.011
Schistosoma mansoni glutamate receptor NMDA 0.0202 0.0533 0.0533
Leishmania major pyruvate kinase 0.0035 0.0056 0.0302
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0148 0.0379 0.0379
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0275 0.0275
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0067 0.0362
Mycobacterium ulcerans hypothetical protein 0.0044 0.0082 0.0414
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi G protein-coupled receptor F59B2.13 0.0065 0.0142 0.0191
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Loa Loa (eye worm) glutamate receptor 1 0.0064 0.014 0.0189
Loa Loa (eye worm) glutamate receptor 2 0.0064 0.014 0.0189
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0016 0.0085
Trypanosoma cruzi histone deacetylase, putative 0.0131 0.0331 0.1801
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0006 0.004
Plasmodium falciparum thioredoxin reductase 0.005 0.0098 0.0973
Leishmania major cathepsin L-like protease 0.0193 0.0509 0.277
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0083 0.0447
Loa Loa (eye worm) FAD binding domain-containing protein 0.0016 0.0003 0.0004
Echinococcus multilocularis 0.0045 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0216 0.0573 0.0573
Onchocerca volvulus 0.0114 0.0281 0.0366
Echinococcus granulosus neuropeptides capa receptor 0.0065 0.0142 0.0142
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0366 0.1001 0.4998
Loa Loa (eye worm) TK/EGFR protein kinase 0.0146 0.0375 0.0506
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0067 0.0308
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0275 0.135
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0249 0.0249
Onchocerca volvulus 0.0114 0.0281 0.0366
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.003 0.029
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0006 0.005
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0009 0.0046
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0114 0.0281 0.0379
Brugia malayi hypothetical protein 0.0065 0.0142 0.0191
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0058 0.0284
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0095
Trypanosoma cruzi histone deacetylase 1, putative 0.0366 0.1001 0.5454
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0361
Plasmodium vivax multidomain scavenger receptor, putative 0.014 0.0356 0.3551
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0096
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0509 0.277
Brugia malayi ecdysone receptor 0.0051 0.0103 0.0138
Echinococcus granulosus lamin dm0 0.0114 0.0281 0.0281
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0371 0.05
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0006
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0079 0.0365
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0109 0.0267 0.0267
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0432 0.2138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0025 0.0095
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0051 0.0102 0.0137
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.001 0.0075
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0054 0.0054
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0056 0.0252
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0174 0.0174
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Echinococcus granulosus allatostatin A receptor 0.0065 0.0142 0.0142
Schistosoma mansoni tyrosine kinase 0.0078 0.0179 0.0179
Brugia malayi G-protein coupled receptor 0.0065 0.0142 0.0191
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0056 0.0076
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0152 0.0391 0.0391
Schistosoma mansoni biogenic amine receptor 0.0065 0.0142 0.0142
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0209 0.0209
Loa Loa (eye worm) intermediate filament protein 0.0114 0.0281 0.0379
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.003 0.029
Mycobacterium tuberculosis Conserved protein 0.0045 0.0085 0.0435
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0065 0.0142 0.0142
Entamoeba histolytica cysteine protease, putative 0.0026 0.0031 0.0055
Loa Loa (eye worm) hypothetical protein 0.0051 0.0103 0.0139
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0043
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0056 0.0302
Trichomonas vaginalis histone deacetylase, putative 0.0366 0.1001 0.4998
Schistosoma mansoni notch 0.0452 0.1247 0.1247
Echinococcus multilocularis lamin dm0 0.0114 0.0281 0.0281
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.0315 0.1691
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0072 0.0388
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0119 0.0616
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0076 0.0174 0.0174
Brugia malayi neuropeptide F receptor 0.0065 0.0142 0.0191
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Brugia malayi hypothetical protein 0.01 0.0241 0.0324
Onchocerca volvulus 0.0452 0.1246 0.1672
Loa Loa (eye worm) hypothetical protein 0.0185 0.0485 0.0656
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0109 0.0267 0.0267
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0044 0.0081 0.0109
Leishmania major cathepsin L-like protease 0.0051 0.0102 0.055
Loa Loa (eye worm) hypothetical protein 0.261 0.7403 1
Entamoeba histolytica hypothetical protein 0.0049 0.0097 0.0724
Loa Loa (eye worm) hypothetical protein 0.0065 0.0142 0.0192
Plasmodium vivax glutathione reductase, putative 0.005 0.0098 0.0973

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.3759 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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