Detailed information for compound 177647

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 572.655 | Formula: C26H33FN8O4S
  • H donors: 4 H acceptors: 5 LogP: 0.12 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C([C@@H]1CC[C@@H]2N1C(=O)CN(C2)C(=O)[C@H](Cc1ccc(cc1)F)N)NC(C(=O)c1nccs1)CCCN=C(N)N
  • InChi: 1S/C26H33FN8O4S/c27-16-5-3-15(4-6-16)12-18(28)25(39)34-13-17-7-8-20(35(17)21(36)14-34)23(38)33-19(2-1-9-32-26(29)30)22(37)24-31-10-11-40-24/h3-6,10-11,17-20H,1-2,7-9,12-14,28H2,(H,33,38)(H4,29,30,32)/t17-,18-,19?,20-/m0/s1
  • InChiKey: ZMFLEXYDURICTN-DQTVCYTJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor II (thrombin) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cyclin A, putative 0.0021 0.0013 0.0033
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0038 0.0069 0.0168
Echinococcus granulosus serine:threonine protein kinase haspin 0.0035 0.0059 0.0064
Schistosoma mansoni axis inhibition protein axin 0.0077 0.019 0.0327
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.011 0.0293 0.113
Plasmodium falciparum thioredoxin reductase 0.0061 0.0141 0.0628
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Brugia malayi MH2 domain containing protein 0.0024 0.0025 0.0028
Leishmania major mitochondrial DNA topoisomerase II 0.0038 0.0069 0.0265
Brugia malayi Nuclear hormone receptor family member nhr-19 0.022 0.0639 0.0698
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0044 0.0108
Mycobacterium leprae Probable two-component sensor kinase 0.0038 0.0069 0.0198
Loa Loa (eye worm) jmjC domain-containing protein 0.0046 0.0093 0.0105
Echinococcus multilocularis Smad4 0.0024 0.0025 0.0028
Schistosoma mansoni pyruvate kinase 0.0045 0.0089 0.0153
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0159 0.0446 0.0487
Trypanosoma brucei cyclin 9 0.0021 0.0013 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0015 0.0202
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.022 0.0639 0.0698
Echinococcus multilocularis smad 0.0024 0.0025 0.0028
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0038 0.0069 0.0168
Echinococcus multilocularis RUN 0.0051 0.0108 0.0118
Brugia malayi tailless protein 0.0104 0.0275 0.03
Schistosoma mansoni DNA topoisomerase type I 0.0371 0.111 0.1916
Loa Loa (eye worm) cyclin domain-containing protein 0.0021 0.0013 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0205 0.0354
Leishmania major DNA polymerase eta, putative 0.0073 0.0178 0.0686
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0142 0.0394 0.068
Mycobacterium ulcerans putative regulatory protein 0.0239 0.0697 0.2138
Schistosoma mansoni regulator of G protein signaling 0.0077 0.019 0.0327
Trichomonas vaginalis cyclin B3, putative 0.0021 0.0013 0.0033
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0033 0.0054 0.0208
Brugia malayi Inositol-1 0.0033 0.0051 0.0056
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0073 0.0177 0.02
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0092 0.0238 0.0268
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0021 0.0013 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.002 0.0078
Echinococcus multilocularis regulator of G protein signaling 0.0077 0.019 0.0207
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0038 0.0069 0.0265
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0056 0.0126 0.0307
Schistosoma mansoni hypothetical protein 0.0192 0.0548 0.0946
Schistosoma mansoni g1/s-specific cyclin C 0.0021 0.0013 0.0023
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.002 0.0035
Trichomonas vaginalis endoplasmin, putative 0.0169 0.0479 0.1171
Brugia malayi Latrophilin receptor protein 2 0.0192 0.0548 0.0599
Onchocerca volvulus 0.0083 0.0209 0.0512
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0844 0.2589 0.2828
Schistosoma mansoni hypothetical protein 0.005 0.0107 0.0184
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0031 0.0047 0.0144
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0021 0.0013 0.006
Loa Loa (eye worm) hypothetical protein 0.0116 0.0314 0.0354
Schistosoma mansoni endoplasmin 0.0242 0.0706 0.1218
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0148 0.0455
Trypanosoma cruzi cyclin, putative 0.0164 0.0463 0.1788
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.035 0.1075
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3098 0.9639 0.9639
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0016
Brugia malayi Smad1 0.0024 0.0025 0.0028
Echinococcus granulosus pyruvate kinase 0.0045 0.0089 0.0097
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.022 0.0639 0.0698
Giardia lamblia Heat shock protein HSP 90-alpha 0.0242 0.0706 0.2165
Trypanosoma brucei mitotic cyclin 6 0.0164 0.0463 0.1788
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0061 0.0141 0.0431
Schistosoma mansoni DNA polymerase eta 0.0073 0.0178 0.0307
Loa Loa (eye worm) 6-phosphofructokinase 0.0078 0.0192 0.0217
Mycobacterium ulcerans hypothetical protein 0.0023 0.002 0.0062
Leishmania major 4-coumarate:coa ligase-like protein 0.0217 0.0627 0.2422
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.011 0.0293 0.1307
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0152 0.0426 0.0465
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0167 0.0471 0.0813
Brugia malayi Doublecortin family protein 0.0051 0.0108 0.0118
Entamoeba histolytica cell division protein kinase 2, putative 0.0073 0.0177 0.0685
Onchocerca volvulus Cyclin L homolog 0.0021 0.0013 0.0033
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.035 0.0605
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Brugia malayi Nuclear hormone receptor family member nhr-49 0.022 0.0639 0.0698
Leishmania major DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Brugia malayi Bromodomain containing protein 0.0275 0.0808 0.0883
Plasmodium vivax acyl-CoA synthetase, putative 0.0162 0.0456 0.2036
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0013 0.0015
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.0581
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0064 0.0148 0.0148
Echinococcus granulosus cyclin dependent kinase 9 0.004 0.0074 0.0081
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0075 0.0289
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0046 0.0093 0.0358
Echinococcus multilocularis pyruvate kinase 0.0045 0.0089 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0084 0.0205
Leishmania major ATP-dependent phosphofructokinase 0.0078 0.0192 0.0742
Echinococcus granulosus lysine specific demethylase 6a 0.0046 0.0093 0.0101
Leishmania major 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0331 0.0986 0.2409
Mycobacterium tuberculosis Long conserved protein 0.1058 0.326 0.326
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.005 0.0107 0.0116
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.1062
Plasmodium falciparum glutathione reductase 0.0177 0.0502 0.2241
Plasmodium vivax protein kinase Crk2 0.0073 0.0177 0.0793
Schistosoma mansoni serine/threonine kinase 0.004 0.0074 0.0128
Schistosoma mansoni inositol monophosphatase 0.0033 0.0051 0.0089
Echinococcus multilocularis lysine specific demethylase 5A 0.0172 0.0487 0.0532
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0331 0.0986 0.2409
Trichomonas vaginalis cyclins, putative 0.0164 0.0463 0.1131
Loa Loa (eye worm) twinkle helicase 0.0072 0.0173 0.0196
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0038 0.0069 0.0075
Plasmodium falciparum cyclin 0.0085 0.0215 0.096
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0077 0.019 0.0464
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Echinococcus granulosus cyclin A3 4 0.0021 0.0013 0.0015
Brugia malayi PHD-finger family protein 0.0053 0.0116 0.0127
Schistosoma mansoni importin beta-1 0.0042 0.008 0.0139
Trypanosoma cruzi mitotic cyclin, putative 0.0021 0.0013 0.0051
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0178 0.0686
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0092 0.0238 0.0581
Echinococcus multilocularis cyclins 0.0085 0.0215 0.0235
Echinococcus multilocularis 6 phosphofructokinase 0.0078 0.0192 0.021
Echinococcus multilocularis lipoxygenase domain containing protein 0.0051 0.0108 0.0118
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0192 0.047
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0092 0.0238 0.0581
Leishmania major alpha glucosidase II subunit, putative 0.003 0.0044 0.017
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0021 0.0015 0.0066
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0092 0.0238 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0033
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0104 0.0274 0.0299
Mycobacterium ulcerans transglutaminase family protein 0.1058 0.326 1
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0038 0.0069 0.0075
Echinococcus granulosus peregrin 0.0155 0.0433 0.0473
Brugia malayi Importin beta-1 subunit 0.0042 0.008 0.0088
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0844 0.2589 0.2828
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0092 0.0238 0.0919
Loa Loa (eye worm) hypothetical protein 0.0414 0.1244 0.1403
Trypanosoma cruzi hypothetical protein, conserved 0.0092 0.0238 0.0919
Toxoplasma gondii PHD-finger domain-containing protein 0.0142 0.0394 0.176
Mycobacterium leprae conserved hypothetical protein 0.0031 0.0047 0.0136
Trypanosoma brucei developmentally regulated phosphoprotein 0.0038 0.0069 0.0265
Plasmodium vivax pyruvate kinase, putative 0.0045 0.0089 0.0397
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0038 0.0069 0.0307
Echinococcus granulosus PHD finger protein rhinoceros 0.0142 0.0394 0.043
Brugia malayi MH1 domain containing protein 0.0024 0.0025 0.0028
Echinococcus granulosus beta-adrenergic receptor kinase 0.0082 0.0205 0.0224
Trypanosoma brucei heat shock protein, putative 0.0242 0.0706 0.2726
Echinococcus granulosus X box binding protein 1 0.0187 0.0534 0.0583
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0046 0.0093 0.016
Brugia malayi regulator of G-protein signaling rgs-7 0.0077 0.019 0.0207
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0073 0.0178 0.0686
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0031 0.0047 0.0642
Giardia lamblia Pyruvate kinase 0.0045 0.0089 0.0273
Echinococcus granulosus ankyrin repeat protein 0.0338 0.1007 0.11
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0099 0.0259 0.1159
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0056 0.0126 0.0562
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.0581
Brugia malayi hypothetical protein 0.0051 0.0108 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0002 0.0005
Echinococcus granulosus ecdysone induced protein 78C 0.022 0.0639 0.0698
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0067 0.0163
Trichomonas vaginalis maltase-glucoamylase, putative 0.003 0.0044 0.0108
Echinococcus granulosus lysine specific demethylase 5A 0.0179 0.0509 0.0556
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0053 0.0114 0.0125
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0038 0.0069 0.0075
Onchocerca volvulus 0.0111 0.0297 0.0727
Brugia malayi Nuclear hormone receptor family member nhr-1 0.022 0.0639 0.0698
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.011 0.0293 0.032
Brugia malayi Endoplasmin precursor 0.0242 0.0706 0.0771
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1337 0.4131 0.4512
Schistosoma mansoni terminal deoxycytidyl transferase 0.0073 0.0178 0.0307
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0015 0.0202
Mycobacterium ulcerans hypothetical protein 0.1058 0.326 1
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0092 0.0238 0.026
Echinococcus granulosus retinoic acid receptor rxr beta a 0.022 0.0639 0.0698
Trypanosoma cruzi hypothetical protein, conserved 0.0092 0.0238 0.0919
Leishmania major DNA topoisomerase IB, large subunit 0.0371 0.111 0.4288
Mycobacterium leprae conserved hypothetical protein 0.0239 0.0697 0.2012
Onchocerca volvulus 0.0079 0.0197 0.048
Echinococcus multilocularis thyroid hormone receptor alpha 0.022 0.0639 0.0698
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0075 0.0183
Brugia malayi Nuclear hormone receptor-like 1 0.022 0.0639 0.0698
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trichomonas vaginalis DNA polymerase eta, putative 0.0073 0.0178 0.0434
Entamoeba histolytica serine/threonine protein kinase, putative 0.0844 0.2589 1
Trypanosoma brucei unspecified product 0.0073 0.0178 0.0686
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.0275 0.03
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0064 0.0148 0.0162
Loa Loa (eye worm) hypothetical protein 0.0138 0.0382 0.0431
Trichomonas vaginalis heat shock protein, putative 0.0219 0.0635 0.1551
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0061 0.0141 0.1916
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0104 0.0275 0.03
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0073 0.0178 0.0307
Echinococcus multilocularis neuropeptide s receptor 0.0378 0.1133 0.1237
Loa Loa (eye worm) hypothetical protein 0.0116 0.0314 0.0354
Trypanosoma cruzi pyruvate kinase 2, putative 0.0045 0.0089 0.0343
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0038 0.0069 0.0307
Entamoeba histolytica phosphofructokinase, putative 0.0078 0.0192 0.0742
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0038 0.0069 0.0198
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0141 0.0543
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0159 0.0446 0.0487
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0217 0.0627 0.1924
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0073 0.0178 0.02
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0128 0.035 0.0383
Mycobacterium leprae Conserved hypothetical protein 0.1058 0.326 0.9407
Loa Loa (eye worm) hypothetical protein 0.0092 0.0238 0.0268
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.022 0.0639 0.1561
Trypanosoma brucei protein kinase, putative 0.004 0.0074 0.0286
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0219 0.0636 0.0694
Brugia malayi MH1 domain containing protein 0.0024 0.0025 0.0028
Loa Loa (eye worm) TAR-binding protein 0.0401 0.1202 0.1356
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.003 0.0044 0.005
Schistosoma mansoni tar DNA-binding protein 0.0401 0.1202 0.2075
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Leishmania major 4-coumarate:coa ligase-like protein 0.0217 0.0627 0.2422
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0331 0.0986 0.1701
Giardia lamblia Heat shock protein HSP 90-alpha 0.0204 0.0586 0.1799
Trypanosoma brucei heat shock protein, putative 0.0242 0.0706 0.2726
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0078 0.0192 0.0742
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0013 0.0015
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0038 0.0069 0.0935
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0152 0.0426 0.1644
Brugia malayi SET domain containing protein 0.0019 0.0008 0.0009
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0046 0.0095 0.0365
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Loa Loa (eye worm) heterochromatin protein 1 0.0078 0.0194 0.0219
Echinococcus multilocularis regulator of G protein signaling 7 0.0077 0.019 0.0207
Echinococcus granulosus cyclin 0.0021 0.0013 0.0015
Mycobacterium ulcerans two component regulator - sensor kinase 0.0038 0.0069 0.021
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.022 0.0639 0.0698
Entamoeba histolytica acyl-CoA synthetase, putative 0.0217 0.0627 0.2422
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0141 0.0543
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0064 0.0148 0.0148
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0141 0.0543
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0092 0.0238 0.026
Echinococcus multilocularis cyclin t1 0.0021 0.0013 0.0015
Echinococcus granulosus jumonji domain containing protein 0.0198 0.0568 0.062
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Plasmodium vivax DNA gyrase subunit B, putative 0.0038 0.0069 0.0307
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0078 0.0192 0.0555
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.004 0.0074 0.0181
Trypanosoma brucei PAB1-binding protein , putative 0.0092 0.0238 0.0918
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0044 0.0108
Echinococcus granulosus lipoxygenase domain containing protein 0.0051 0.0108 0.0118
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0002 0.0002
Brugia malayi GSG2 0.0035 0.0059 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Plasmodium falciparum topoisomerase I 0.0496 0.15 0.6701
Echinococcus multilocularis kinase protein 0.0085 0.0214 0.0234
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.002 0.009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0015
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0217 0.0627 0.1924
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0025 0.0028
Entamoeba histolytica hypothetical protein 0.0104 0.0274 0.1057
Echinococcus multilocularis chromobox protein 1 0.0078 0.0194 0.0212
Echinococcus multilocularis zinc finger protein 0.0075 0.0183 0.02
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0064 0.0148 0.0428
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.1062
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.011 0.0293 0.032
Trypanosoma cruzi hypothetical protein, conserved 0.0092 0.0238 0.0919
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0092 0.0238 0.0581
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0092 0.0238 0.026
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Giardia lamblia Cyclin fold protein 1, putative 0.0021 0.0013 0.0041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0141 0.0543
Plasmodium falciparum cyclin 1 0.0021 0.0013 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.022 0.0639 0.0721
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0162 0.0456 0.0456
Echinococcus granulosus cyclin k 0.0021 0.0013 0.0015
Echinococcus granulosus cyclin dependent kinase 5 0.0073 0.0177 0.0194
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.019 0.0464
Schistosoma mansoni regulator of G protein signaling 0.0077 0.019 0.0327
Loa Loa (eye worm) pyruvate kinase 0.0045 0.0089 0.01
Treponema pallidum heat shock protein 90 0.0219 0.0635 0.8652
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.011 0.0293 0.032
Plasmodium falciparum pyruvate kinase 2 0.0023 0.0021 0.0093
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0152 0.0426 0.1644
Onchocerca volvulus 0.0104 0.0275 0.0671
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0092 0.0238 0.026
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0116 0.0314 0.0354
Giardia lamblia Transglutaminase/protease, putative 0.1058 0.326 1
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0038 0.0069 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.002 0.0078
Echinococcus granulosus Cell division cycle 2 protein kinase 0.004 0.0074 0.0081
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0038 0.0069 0.0069
Entamoeba histolytica acyl-CoA synthetase, putative 0.0217 0.0627 0.2422
Brugia malayi AMP-binding enzyme family protein 0.0217 0.0627 0.0685
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0073 0.0177 0.0685
Trypanosoma brucei heat shock protein 90, putative 0.0242 0.0706 0.2726
Loa Loa (eye worm) hypothetical protein 0.0116 0.0314 0.0354
Plasmodium falciparum glutathione reductase 0.0061 0.0141 0.0628
Schistosoma mansoni hypothetical protein 0.1869 0.5795 1
Echinococcus multilocularis isocitrate dehydrogenase 0.011 0.0293 0.032
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0092 0.0238 0.026
Toxoplasma gondii pyruvate kinase PyK1 0.0045 0.0089 0.0397
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0064 0.0148 0.0455
Schistosoma mansoni tar DNA-binding protein 0.0401 0.1202 0.2075
Brugia malayi Bromodomain containing protein 0.0142 0.0394 0.043
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0092 0.0238 0.0919
Loa Loa (eye worm) hypothetical protein 0.0077 0.019 0.0214
Brugia malayi jmjC domain containing protein 0.0046 0.0093 0.0101
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0092 0.0238 0.026
Echinococcus granulosus G1:S specific cyclin D1 0.0021 0.0013 0.0015
Brugia malayi 6-phosphofructokinase 0.0078 0.0192 0.021
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.011 0.0293 0.1307
Toxoplasma gondii thioredoxin reductase 0.0177 0.0502 0.2241
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0033
Trichomonas vaginalis heat shock protein, putative 0.0219 0.0635 0.1551
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0147 0.0408 0.0998
Loa Loa (eye worm) jmjC domain-containing protein 0.0179 0.0509 0.0574
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0086 0.0211
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0338 0.1007 0.1737
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0178 0.0686
Giardia lamblia G2/mitotic-specific cyclin B 0.0164 0.0463 0.142
Loa Loa (eye worm) hypothetical protein 0.0034 0.0057 0.0064
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0073 0.0177 0.0793
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0277 0.0817 0.2505
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0403 0.1209 0.1209
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Trichomonas vaginalis cyclins, putative 0.0021 0.0013 0.0033
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0178 0.0686
Schistosoma mansoni lipoxygenase 0.0156 0.0438 0.0756
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0033 0.0054 0.0059
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.035 0.1075
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0148 0.0162
Brugia malayi ecdysteroid receptor 0.022 0.0639 0.0698
Toxoplasma gondii PHD-finger domain-containing protein 0.0142 0.0394 0.176
Trypanosoma cruzi heat shock protein 90, putative 0.0111 0.0295 0.1141
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Echinococcus granulosus lipoxygenase domain containing protein 0.0051 0.0108 0.0118
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Mycobacterium ulcerans hypothetical protein 0.0217 0.0627 0.1924
Plasmodium vivax cyclin homologue, putative 0.0021 0.0013 0.006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.022 0.0639 0.0698
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.0033 0.0054 0.024
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.002 0.0078
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0097 0.0237
Leishmania major DNA polymerase kappa, putative 0.0023 0.002 0.0078
Echinococcus granulosus axis inhibition protein axin 0.0077 0.019 0.0207
Echinococcus multilocularis microtubule associated protein 2 0.1621 0.5019 0.5482
Onchocerca volvulus 0.0064 0.0148 0.0362
Mycobacterium tuberculosis Hypothetical protein 0.1058 0.326 0.326
Loa Loa (eye worm) hypothetical protein 0.0142 0.0394 0.0444
Echinococcus multilocularis L aminoadipate semialdehyde 0.0111 0.0297 0.0325
Loa Loa (eye worm) DR-78 0.0104 0.0275 0.031
Echinococcus granulosus smad 0.0024 0.0025 0.0028
Schistosoma mansoni cyclins 0.0085 0.0215 0.0371
Schistosoma mansoni axis inhibition protein axin 0.0077 0.019 0.0327
Trichomonas vaginalis peptide N-glycanase, putative 0.1058 0.326 0.7966
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0331 0.0986 0.3808
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.004 0.0074 0.0083
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0192 0.047
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0152 0.0426 0.1644
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0064 0.0148 0.0428
Echinococcus multilocularis pyruvate kinase 0.0045 0.0089 0.0097
Plasmodium vivax SET domain containing protein 0.0019 0.0008 0.0034
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0167 0.0471 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trypanosoma cruzi cyclin, putative 0.0164 0.0463 0.1788
Trypanosoma cruzi trypanothione reductase, putative 0.0061 0.0141 0.0543
Trichomonas vaginalis pyruvate kinase, putative 0.0045 0.0089 0.0217
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0038 0.0069 0.0265
Leishmania major cyclin 0.0164 0.0463 0.1788
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0074 0.0181
Giardia lamblia GTOR 0.005 0.0107 0.0329
Entamoeba histolytica hypothetical protein 0.0104 0.0274 0.1057
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.022 0.0639 0.0698
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0067 0.0163
Echinococcus granulosus jumonji domain containing 1A 0.0046 0.0093 0.0101
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0162 0.0456 0.621
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0085 0.0214 0.0234
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.0581
Echinococcus granulosus nuclear receptor 2DBD gamma 0.022 0.0639 0.0698
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0086 0.0211
Trypanosoma brucei unspecified product 0.005 0.0107 0.0412
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0161 0.0452 0.0494
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0448 0.135 0.135
Trypanosoma cruzi mitotic cyclin, putative 0.0021 0.0013 0.0051
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0038 0.0069 0.0168
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0033 0.0054 0.0208
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0061 0.0141 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0046 0.0113
Plasmodium vivax heat shock protein 90, putative 0.0147 0.0408 0.1824
Toxoplasma gondii DNA topoisomerase 2, putative 0.0038 0.0069 0.0307
Trichomonas vaginalis cyclin D, putative 0.0021 0.0013 0.0033
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0092 0.0238 0.0919
Brugia malayi Pre-SET motif family protein 0.0167 0.0471 0.0515
Plasmodium falciparum importin beta, putative 0.0042 0.008 0.0359
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0448 0.135 0.135
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0013 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0075 0.0183
Brugia malayi Nuclear hormone receptor-like 1 0.0116 0.0314 0.0342
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0038 0.0069 0.0069
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0251 0.0734 0.2118
Loa Loa (eye worm) hypothetical protein 0.0146 0.0404 0.0456
Schistosoma mansoni protein phosphatase-2b 0.0033 0.0054 0.0093
Brugia malayi MH2 domain containing protein 0.0024 0.0025 0.0028
Trypanosoma cruzi importin beta-1 subunit, putative 0.0034 0.0056 0.0215
Trichomonas vaginalis cyclin B, putative 0.0085 0.0215 0.0525
Entamoeba histolytica acyl-coA synthetase, putative 0.0217 0.0627 0.2422
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.011 0.0293 0.113
Loa Loa (eye worm) hypothetical protein 0.022 0.0639 0.0721
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0045 0.0089 0.01
Plasmodium vivax hypothetical protein, conserved 0.0239 0.0697 0.3115
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.002 0.009
Mycobacterium tuberculosis Conserved hypothetical protein 0.1058 0.326 0.326
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.1062
Schistosoma mansoni hypothetical protein 0.0021 0.0016 0.0027
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0605 0.1843 0.2078
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0097 0.0237
Plasmodium falciparum 60S ribosomal protein L19 0.0021 0.0015 0.0065
Loa Loa (eye worm) hypothetical protein 0.0162 0.0456 0.0514
Echinococcus multilocularis kinase protein 0.0085 0.0214 0.0234
Echinococcus multilocularis serine:threonine protein kinase NLK 0.004 0.0074 0.0081
Toxoplasma gondii phosphofructokinase PFKII 0.0021 0.0015 0.0066
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0033 0.0051 0.0126
Entamoeba histolytica deoxycytidyl transferase, putative 0.0073 0.0178 0.0686
Giardia lamblia Kinase, CMGC CDK 0.0073 0.0177 0.0544
Schistosoma mansoni rab6-interacting 0.0051 0.0108 0.0186
Schistosoma mansoni pyruvate kinase 0.0045 0.0089 0.0153
Trichomonas vaginalis cyclins, putative 0.0021 0.0013 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0107 0.0412
Brugia malayi hypothetical protein 0.0104 0.0275 0.03
Echinococcus multilocularis transient receptor potential cation channel 0.0345 0.1028 0.1123
Brugia malayi Protein kinase domain containing protein 0.004 0.0074 0.0081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.022 0.0639 0.0721
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0061 0.0141 0.0543
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0064 0.0148 0.0662
Loa Loa (eye worm) hypothetical protein 0.0077 0.019 0.0214
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0104 0.0275 0.0474
Loa Loa (eye worm) DNA topoisomerase I 0.0496 0.15 0.1691
Leishmania major hypothetical protein, conserved 0.0092 0.0238 0.0919
Loa Loa (eye worm) hypothetical protein 0.0228 0.0664 0.0749
Echinococcus multilocularis cyclins 0.0085 0.0215 0.0235
Schistosoma mansoni nuclear receptor nhr-48 0.0104 0.0275 0.0474
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0038 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.005 0.0107 0.0184
Loa Loa (eye worm) jmjC domain-containing protein 0.0046 0.0093 0.0105
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0033
Plasmodium vivax importin-beta 2, putative 0.0042 0.008 0.0359
Loa Loa (eye worm) hypothetical protein 0.0162 0.0456 0.0514
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0107 0.0412
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0092 0.0238 0.041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Echinococcus granulosus Polycystic kidney disease protein 0.0051 0.0108 0.0118
Loa Loa (eye worm) hypothetical protein 0.022 0.0639 0.0721
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0194 0.0474
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.004 0.0074 0.0081
Echinococcus granulosus cyclins 0.0085 0.0215 0.0235
Loa Loa (eye worm) hypothetical protein 0.0162 0.0456 0.0514
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0015
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.0033 0.0054 0.024
Loa Loa (eye worm) pyruvate kinase 0.0045 0.0089 0.01
Schistosoma mansoni hypothetical protein 0.0051 0.0108 0.0186
Leishmania major hypothetical protein, conserved 0.0055 0.0122 0.0471
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0051 0.0199
Giardia lamblia Kinase, CAMK CAMKL 0.004 0.0074 0.0227
Loa Loa (eye worm) hypothetical protein 0.0046 0.0093 0.0105
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.0581
Trypanosoma cruzi DNA repair protein, putative 0.0042 0.008 0.0308
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.004 0.0074 0.0286
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0021 0.0013 0.006
Brugia malayi nuclear receptor RXR 0.0116 0.0314 0.0342
Echinococcus granulosus dna polymerase eta 0.0073 0.0178 0.0194
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0024 0.0092
Brugia malayi hypothetical protein 0.0092 0.0238 0.026
Schistosoma mansoni zinc finger protein 0.0055 0.0122 0.021
Brugia malayi STAT protein, DNA binding domain containing protein 0.0132 0.0364 0.0397
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.035 0.0605
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0092 0.0238 0.041
Echinococcus granulosus serine:threonine protein kinase haspin 0.0035 0.0059 0.0064
Schistosoma mansoni tar DNA-binding protein 0.0401 0.1202 0.2075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0002 0.0005
Toxoplasma gondii propionate-CoA ligase 0.0064 0.0148 0.0662
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.002 0.0078
Echinococcus granulosus cyclin G2 0.0021 0.0013 0.0015
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.003 0.0044 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0002 0.0005
Schistosoma mansoni methyl-cpg binding protein mbd 0.0062 0.0142 0.0245
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0015 0.0036
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0084
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0045 0.0089 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.0697 0.1703
Brugia malayi nuclear hormone receptor family member odr-7 0.0104 0.0275 0.03
Mycobacterium leprae Conserved hypothetical protein 0.1124 0.3465 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0084
Toxoplasma gondii pyruvate kinase PyKII 0.0023 0.0021 0.0093
Loa Loa (eye worm) hypothetical protein 0.0217 0.0627 0.0707
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0205 0.0354
Leishmania major DNA damage repair protein, putative 0.0023 0.002 0.0078
Schistosoma mansoni retinoid-x-receptor (RXR) 0.022 0.0639 0.1102
Plasmodium vivax heat shock protein 86, putative 0.0242 0.0706 0.3153
Loa Loa (eye worm) cyclin domain-containing protein 0.0021 0.0013 0.0015
Brugia malayi hypothetical protein 0.0077 0.019 0.0207
Onchocerca volvulus 0.0217 0.0627 0.1532
Trypanosoma brucei DNA polymerase eta, putative 0.0073 0.0178 0.0686
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0044 0.0106
Schistosoma mansoni polycystin 1-related 0.0051 0.0108 0.0186
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0038 0.0069 0.021
Echinococcus multilocularis cyclins 0.0085 0.0215 0.0235
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.004 0.0074 0.0286
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0167
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0092 0.0238 0.026
Brugia malayi hypothetical protein 0.0021 0.0013 0.0015
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Loa Loa (eye worm) hypothetical protein 0.0079 0.0197 0.0222
Echinococcus multilocularis cyclin 0.0021 0.0013 0.0015
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0331 0.0986 0.1701
Echinococcus multilocularis tar DNA binding protein 0.0401 0.1202 0.1313
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0092 0.0238 0.026
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0033 0.0054 0.0208
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0152 0.0426 0.0465
Trypanosoma brucei pyruvate kinase 1, putative 0.0045 0.0089 0.0343
Leishmania major acetyl-CoA synthetase, putative 0.0064 0.0148 0.0573
Trichomonas vaginalis antibiotic synthetase, putative 0.0064 0.0148 0.0362
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.005 0.0107 0.0116
Brugia malayi CHD4 protein 0.002 0.0011 0.0012
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0077 0.019 0.0327
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0067 0.0298
Loa Loa (eye worm) hypothetical protein 0.0217 0.0627 0.0707
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Mycobacterium ulcerans acetyl-CoA synthetase 0.0064 0.0148 0.0455
Entamoeba histolytica cyclin, putative 0.0085 0.0215 0.083
Plasmodium vivax thioredoxin reductase, putative 0.0177 0.0502 0.2241
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Loa Loa (eye worm) hypothetical protein 0.0217 0.0627 0.0707
Echinococcus multilocularis ribosomal protein L19 0.0021 0.0015 0.0016
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0038 0.0069 0.0265
Brugia malayi 60S ribosomal protein L19 0.0021 0.0015 0.0016
Chlamydia trachomatis DNA gyrase subunit B 0.0038 0.0069 0.0935
Echinococcus multilocularis cyclin k 0.0021 0.0013 0.0015
Echinococcus granulosus regulator of G protein signaling 7 0.0077 0.019 0.0207
Onchocerca volvulus 0.0051 0.0108 0.0263
Schistosoma mansoni hypothetical protein 0.0414 0.1244 0.2146
Echinococcus granulosus DNA topoisomerase 1 0.0496 0.15 0.1638
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.022 0.0639 0.1102
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Loa Loa (eye worm) hypothetical protein 0.0077 0.019 0.0214
Trypanosoma brucei heat shock protein, putative 0.0242 0.0706 0.2726
Loa Loa (eye worm) hypothetical protein 0.0051 0.0108 0.0121
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0217 0.0627 0.0627
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.2943 0.9155 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0019 0.0008 0.0034
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.2943 0.9155 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Echinococcus granulosus serine:threonine protein kinase haspin 0.0035 0.0059 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2589 0.6326
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0331 0.0986 0.3808
Mycobacterium leprae Probable two component sensor kinase MprB 0.0038 0.0069 0.0198
Schistosoma mansoni phosphatidylserine receptor 0.0046 0.0093 0.016
Trypanosoma brucei importin beta-1 subunit, putative 0.0042 0.008 0.0311
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Leishmania major cyclin 9, putative 0.0021 0.0013 0.0051
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0033 0.0054 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Plasmodium vivax SET domain protein, putative 0.0167 0.0471 0.2106
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0061 0.0141 0.0543
Schistosoma mansoni protein kinase 0.004 0.0074 0.0128
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0043 0.0104
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0136 0.0373 0.1077
Loa Loa (eye worm) pyruvate kinase 0.0045 0.0089 0.01
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0086 0.0386
Mycobacterium ulcerans acyl-CoA synthetase 0.0217 0.0627 0.1924
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.011 0.0293 0.113
Brugia malayi nuclear hormone receptor 0.0104 0.0275 0.03
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0092 0.0238 0.041
Plasmodium falciparum heat shock protein 90, putative 0.0131 0.036 0.1607
Loa Loa (eye worm) haspin protein kinase 0.0035 0.0059 0.0066
Toxoplasma gondii 6-phosphofructokinase 0.0021 0.0015 0.0066
Plasmodium vivax multidomain scavenger receptor, putative 0.0051 0.0108 0.0481
Loa Loa (eye worm) isocitrate dehydrogenase 0.011 0.0293 0.033
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0177 0.0433
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0262 0.077 0.0841
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0148 0.0162
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0077 0.019 0.0327
Trichomonas vaginalis heat shock protein, putative 0.0131 0.036 0.0879
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0344 0.1024 0.1119
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0092 0.0238 0.041
Mycobacterium ulcerans two component sensor kinase MprB 0.0038 0.0069 0.021
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.005 0.0107 0.0414
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0092 0.0238 0.0919
Entamoeba histolytica heat shock protein 90, putative 0.0242 0.0706 0.2726
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Giardia lamblia Kinase, CMGC CDK 0.0073 0.0177 0.0544
Echinococcus granulosus pyruvate kinase 0.0023 0.0021 0.0023
Loa Loa (eye worm) heat shock protein 90 0.0242 0.0706 0.0796
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0061 0.0141 0.0431
Brugia malayi hypothetical protein 0.0051 0.0108 0.0118
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0021 0.0015 0.0202
Entamoeba histolytica cyclin, putative 0.0164 0.0463 0.1788
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0141 0.0543
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0092 0.0238 0.026
Toxoplasma gondii cyclin dependent kinase binding protein 0.0021 0.0013 0.006
Brugia malayi polk-prov protein 0.0023 0.002 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-25 0.022 0.0639 0.0698
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0035 0.0059 0.0064
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0038 0.0069 0.0075
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0401 0.1202 0.1356
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0192 0.0548 0.0599
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0002 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0061 0.0141 0.0154
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.005 0.0107 0.0117
Leishmania major mitotic cyclin, putative 0.0021 0.0013 0.0051
Echinococcus multilocularis pyruvate kinase 0.0023 0.0021 0.0023
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0064 0.0148 0.0428
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Brugia malayi hypothetical protein 0.0035 0.0059 0.0064
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0111 0.0297 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.0697 0.1703
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0011
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0064 0.0148 0.0162
Schistosoma mansoni heat shock protein 0.0242 0.0706 0.1218
Trichomonas vaginalis CAMK family protein kinase 0.0419 0.1259 0.3077
Giardia lamblia Ribosomal protein L19 0.0021 0.0015 0.0045
Trichomonas vaginalis cyclins, putative 0.0085 0.0215 0.0525
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.011 0.0293 0.032
Loa Loa (eye worm) transcription factor SMAD2 0.0358 0.1069 0.1206
Mycobacterium ulcerans acyl-CoA synthetase 0.0217 0.0627 0.1924
Echinococcus multilocularis ankyrin repeat protein 0.0338 0.1007 0.11
Brugia malayi Cyclin, N-terminal domain containing protein 0.0164 0.0463 0.0505
Leishmania major trypanothione reductase 0.0177 0.0502 0.1938
Brugia malayi latrophilin 2 splice variant baaae 0.0414 0.1244 0.1358
Trichomonas vaginalis heat shock protein, putative 0.0204 0.0586 0.1433
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0448 0.135 0.1523
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0083 0.0209 0.0229
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0073 0.0177 0.02
Echinococcus granulosus fetal alzheimer antigen falz 0.0081 0.0204 0.0222
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0448 0.135 0.3896
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0021 0.0013 0.0015
Mycobacterium tuberculosis Possible two component sensor kinase 0.0038 0.0069 0.0069
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0128 0.035 0.1354
Loa Loa (eye worm) hypothetical protein 0.0073 0.0176 0.0199
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0104 0.0275 0.03
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.004 0.0074 0.0286
Loa Loa (eye worm) hypothetical protein 0.0255 0.0748 0.0843
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0152 0.0426 0.048
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0192 0.0548 0.0599
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Echinococcus multilocularis heat shock protein 90 0.0242 0.0706 0.0771
Onchocerca volvulus 0.0164 0.0463 0.1131
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0159 0.0446 0.0487
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0075 0.0183
Trypanosoma cruzi PAB1-binding protein , putative 0.0092 0.0238 0.0918
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0092 0.0238 0.026
Echinococcus multilocularis GPCR, family 2 0.0192 0.0548 0.0599
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0034 0.0056 0.0136
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0153 0.0428 0.0428
Treponema pallidum NADH oxidase 0.0061 0.0141 0.1916
Echinococcus multilocularis lysosomal alpha glucosidase 0.0137 0.0377 0.0412
Schistosoma mansoni cyclin G 0.0021 0.0013 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.019 0.0464
Echinococcus granulosus cyclin y 0.0021 0.0013 0.0015
Trypanosoma cruzi polo-like protein kinase, putative 0.0844 0.2589 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0192 0.0548 0.0599
Schistosoma mansoni chromobox protein 0.0078 0.0194 0.0335
Brugia malayi nuclear hormone receptor 0.022 0.0639 0.0698
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0148 0.0573
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0371 0.111 0.4288
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0137 0.0377 0.0425
Schistosoma mansoni nuclear receptor 0.0104 0.0275 0.0474
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0081 0.0204 0.0351
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0021 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0271 0.0796 0.0898
Loa Loa (eye worm) latrophilin receptor protein 2 0.0192 0.0548 0.0618
Onchocerca volvulus 0.1325 0.4093 1
Schistosoma mansoni glutaminase 0.062 0.1889 0.326
Echinococcus granulosus histone acetyltransferase KAT2B 0.0158 0.0444 0.0485
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0033 0.0054 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0002 0.0005
Trichomonas vaginalis glutathione reductase, putative 0.0061 0.0141 0.0344
Trypanosoma brucei unspecified product 0.005 0.0107 0.0412
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0015 0.0057
Loa Loa (eye worm) phosphofructokinase 0.0078 0.0192 0.0217
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0015 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.0275 0.03
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0092 0.0238 0.041
Loa Loa (eye worm) hypothetical protein 0.0408 0.1225 0.1382
Trichomonas vaginalis serine/threonine kinase, putative 0.004 0.0074 0.0181
Schistosoma mansoni nuclear hormone receptor 0.0104 0.0275 0.0474
Schistosoma mansoni smad1 5 8 and 0.0024 0.0025 0.0044
Entamoeba histolytica cyclin family protein 0.0085 0.0215 0.083
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0147 0.0408 0.1577
Echinococcus granulosus phd:f box containing protein 0.0046 0.0093 0.0101
Trypanosoma brucei importin beta-1 subunit, putative 0.0042 0.008 0.0311
Trichomonas vaginalis CAMK family protein kinase 0.0879 0.2699 0.6594
Echinococcus multilocularis thioredoxin glutathione reductase 0.0177 0.0503 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0086 0.0211
Schistosoma mansoni acetyl-CoA synthetase 0.0064 0.0148 0.0256
Plasmodium falciparum cysteine repeat modular protein 1 0.0021 0.0016 0.007
Brugia malayi hypothetical protein 0.0021 0.0013 0.0015
Echinococcus granulosus chromobox protein 1 0.0078 0.0194 0.0212
Treponema pallidum replicative DNA helicase (dnaB) 0.0251 0.0734 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0061 0.0141 0.0141
Brugia malayi Pyruvate kinase, muscle isozyme 0.0045 0.0089 0.0097
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0064 0.0148 0.0167
Trichomonas vaginalis cyclin D, putative 0.0085 0.0215 0.0525
Trypanosoma cruzi heat shock protein 85, putative 0.0242 0.0706 0.2726
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.022 0.0639 0.1102
Schistosoma mansoni hypothetical protein 0.1058 0.326 0.5626
Echinococcus granulosus cyclins 0.0085 0.0215 0.0235
Brugia malayi 6-phosphofructokinase 0.0078 0.0192 0.021
Loa Loa (eye worm) jmjC domain-containing protein 0.0046 0.0093 0.0105
Trypanosoma cruzi ISWI complex protein 0.0055 0.0122 0.0471
Entamoeba histolytica phosphofructokinase, putative 0.0078 0.0192 0.0742
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0064 0.0148 0.0455
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0141 0.0543
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0031 0.0047 0.021
Echinococcus granulosus cyclin y 0.0021 0.0013 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.019 0.0464
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0104 0.0275 0.03
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Trypanosoma brucei protein phosphatase 2B, putative 0.0033 0.0054 0.0208
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0016 0.0061
Toxoplasma gondii heat shock protein 75, putative 0.0147 0.0408 0.1824
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Treponema pallidum recombinase A 0.0136 0.0373 0.5087
Echinococcus multilocularis ribosomal protein L19 0.0021 0.0015 0.0016
Trichomonas vaginalis antibiotic synthetase, putative 0.0064 0.0148 0.0362
Plasmodium vivax hypothetical protein, conserved 0.0142 0.0394 0.176
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0153 0.0428 0.0428
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0064 0.0148 0.0455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0052 0.0126
Leishmania major developmentally regulated phosphoprotein-like protein 0.0038 0.0069 0.0265
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.022 0.0639 0.0721
Toxoplasma gondii hypothetical protein 0.0239 0.0697 0.3115
Echinococcus granulosus heat shock protein 0.0242 0.0706 0.0771
Entamoeba histolytica hypothetical protein 0.0104 0.0274 0.1057
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0038 0.0069 0.0069
Echinococcus granulosus thioredoxin glutathione reductase 0.0177 0.0503 0.0549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0002 0.0005
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0082 0.0205 0.0231
Schistosoma mansoni cyclin l 0.0021 0.0013 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.0056 0.0126 0.0307
Brugia malayi Nuclear hormone receptor family member nhr-3 0.022 0.0639 0.0698
Loa Loa (eye worm) hypothetical protein 0.0164 0.0463 0.0522
Brugia malayi ecdysone receptor 0.0104 0.0275 0.03
Echinococcus granulosus methyl CpG binding domain protein 2 0.0062 0.0142 0.0155
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0148 0.0148
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0051 0.0199
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Toxoplasma gondii cyclin 4, putative 0.0021 0.0013 0.006
Entamoeba histolytica hypothetical protein 0.0031 0.0047 0.0182
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0159 0.0446 0.0769
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0148 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2589 0.6326
Schistosoma mansoni 60S ribosomal protein L19 0.0021 0.0015 0.0025
Trypanosoma brucei cyclin 3 0.0021 0.0013 0.0051
Giardia lamblia Grp94/Hsp90 0.0219 0.0635 0.1948
Giardia lamblia DINP protein human, muc B family 0.0073 0.0178 0.0545
Schistosoma mansoni serine/threonine protein kinase 0.0844 0.2589 0.4468
Echinococcus multilocularis pyruvate kinase 0.0023 0.0021 0.0023
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0086 0.0334
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0148 0.0573
Loa Loa (eye worm) hypothetical protein 0.0092 0.0238 0.0268
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0025 0.0028
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0192 0.0548 0.0599
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0038 0.0069 0.0168
Echinococcus granulosus nuclear receptor nhr 48 0.0104 0.0275 0.03
Leishmania major serine/threonine protein phosphatase, putative 0.0033 0.0054 0.0208
Brugia malayi PHD-finger family protein 0.0142 0.0394 0.043
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0081 0.0204 0.0222
Plasmodium vivax 60S ribosomal protein L19, putative 0.0021 0.0015 0.0065
Brugia malayi RNA binding protein 0.0401 0.1202 0.1313
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0044 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Leishmania major hypothetical protein, conserved 0.0092 0.0238 0.0919
Trypanosoma brucei heat shock protein, putative 0.0242 0.0706 0.2726
Echinococcus multilocularis pyruvate kinase 0.0023 0.0021 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.002 0.0078
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0002 0.0008
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0217 0.0627 0.0627
Toxoplasma gondii GAF domain-containing protein 0.0239 0.0697 0.3115
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.0919
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.005 0.0107 0.0117
Mycobacterium tuberculosis Probable reductase 0.0403 0.1209 0.1209
Giardia lamblia Kinase, CAMK CAMKL 0.004 0.0074 0.0227
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0331 0.0986 0.3808
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Loa Loa (eye worm) RGS-3 protein 0.0077 0.019 0.0214
Mycobacterium tuberculosis Probable oxidoreductase 0.0448 0.135 0.135
Echinococcus multilocularis snurportin 1 0.0448 0.135 0.1475
Entamoeba histolytica hypothetical protein 0.0077 0.019 0.0733
Toxoplasma gondii cell-cycle-associated protein kinase, putative 0.0501 0.1515 0.677
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0038 0.0069 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0331 0.0986 0.2409
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0013 0.0015
Brugia malayi regulator of G-protein signaling egl-10 0.0077 0.019 0.0207
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.022 0.0639 0.1102
Toxoplasma gondii DNA topoisomerase I, putative 0.0496 0.15 0.6701
Loa Loa (eye worm) hypothetical protein 0.0042 0.008 0.0091
Trichomonas vaginalis cyclins, putative 0.0164 0.0463 0.1131
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0038 0.0069 0.0168
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.002 0.0011 0.0012
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0219 0.0636 0.0694
Loa Loa (eye worm) hypothetical protein 0.0077 0.019 0.0214
Echinococcus granulosus pyruvate kinase 0.0023 0.0021 0.0023
Schistosoma mansoni heat shock protein 0.0147 0.0408 0.0704
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0021 0.0015 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Loa Loa (eye worm) cyclin domain-containing protein 0.0021 0.0013 0.0015
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0038 0.0069 0.0935
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.011 0.0293 0.032
Toxoplasma gondii aldehyde dehydrogenase 0.0128 0.035 0.1566
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.022 0.0639 0.0721
Brugia malayi Nuclear hormone receptor family member nhr-14 0.022 0.0639 0.0698
Schistosoma mansoni nuclear hormone receptor 0.022 0.0639 0.1102
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0038 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0192 0.0548 0.0946
Echinococcus multilocularis cyclin B 0.0164 0.0463 0.0505
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0104 0.0275 0.03
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0021 0.0015 0.0036
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.005 0.0107 0.0116
Trichomonas vaginalis mercuric reductase, putative 0.0061 0.0141 0.0344
Echinococcus granulosus 6 phosphofructokinase 0.0078 0.0192 0.021
Plasmodium falciparum heat shock protein 90 0.0242 0.0706 0.3153
Mycobacterium ulcerans acyl-CoA synthetase 0.0217 0.0627 0.1924
Echinococcus granulosus Regulator of G protein signaling 20 0.0077 0.019 0.0207
Brugia malayi nuclear receptor NHR-88 0.022 0.0639 0.0698
Trichomonas vaginalis AGC family protein kinase 0.004 0.0074 0.0181
Echinococcus granulosus cyclins 0.0085 0.0215 0.0235
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Onchocerca volvulus Cyclin L homolog 0.0021 0.0013 0.0033
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Trypanosoma cruzi PAB1-binding protein , putative 0.0092 0.0238 0.0918
Schistosoma mansoni zinc finger protein 0.0075 0.0183 0.0315
Brugia malayi cell division control protein 2 homolog 0.0073 0.0177 0.0194
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0331 0.0986 0.3808
Schistosoma mansoni hypothetical protein 0.0192 0.0548 0.0946
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0031 0.0047 0.0047
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0092 0.0238 0.0581
Echinococcus multilocularis hypothetical protein 0.0035 0.0059 0.0064
Brugia malayi TAR-binding protein 0.0401 0.1202 0.1313
Loa Loa (eye worm) cyclin C 0.0021 0.0013 0.0015
Schistosoma mansoni regulator of G protein signaling 0.0077 0.019 0.0327
Trypanosoma brucei isocitrate dehydrogenase, putative 0.011 0.0293 0.113
Loa Loa (eye worm) inositol-1 0.0033 0.0051 0.0058
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0331 0.0986 0.1077
Schistosoma mansoni z-protein (S1r protein) 0.0077 0.019 0.0327
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0038 0.0069 0.0935
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Giardia lamblia Pyruvate kinase 0.0023 0.0021 0.0064
Schistosoma mansoni kinase 0.043 0.1294 0.2233
Echinococcus multilocularis jumonji domain containing protein 0.0198 0.0568 0.062
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0062 0.0142 0.0155
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0403 0.1209 0.1209
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Brugia malayi jmjC domain containing protein 0.0046 0.0093 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0092 0.0238 0.041
Brugia malayi Nuclear hormone receptor family member nhr-19 0.022 0.0639 0.0698
Entamoeba histolytica hypothetical protein 0.0104 0.0274 0.1057
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Brugia malayi cyclin fold protein 1 variant b 0.0021 0.0013 0.0015
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0064 0.0148 0.0455
Plasmodium falciparum thioredoxin reductase 0.0177 0.0502 0.2241
Toxoplasma gondii PHD-finger domain-containing protein 0.0046 0.0095 0.0422
Loa Loa (eye worm) hypothetical protein 0.0068 0.0162 0.0183
Trypanosoma brucei heat shock protein 84, putative 0.0147 0.0408 0.1577
Brugia malayi Glycosyl hydrolases family 31 protein 0.003 0.0044 0.0048
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0083 0.0209 0.0236
Onchocerca volvulus Protein CNPPD1 homolog 0.0021 0.0013 0.0033
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0061 0.0141 0.0628
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.022 0.0639 0.1102
Schistosoma mansoni jumonji domain containing protein 0.037 0.1106 0.1909
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0038 0.0069 0.0935
Echinococcus multilocularis lysosomal alpha glucosidase 0.0137 0.0377 0.0412
Brugia malayi hypothetical protein 0.0077 0.019 0.0207
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0104 0.0275 0.0474
Onchocerca volvulus Protein ultraspiracle homolog 0.022 0.0639 0.1561
Mycobacterium ulcerans DNA polymerase IV 0.0073 0.0178 0.0545
Mycobacterium tuberculosis Conserved protein 0.1058 0.326 0.326
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0078 0.0192 0.0742
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.022 0.0639 0.0698
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0148 0.0455
Trypanosoma cruzi heat shock protein 90, putative 0.0242 0.0706 0.2726
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0073 0.0177 0.0194
Schistosoma mansoni hypothetical protein 0.0192 0.0548 0.0946
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0002 0.0002
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0038 0.0069 0.021
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0038 0.0069 0.0935
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Brugia malayi hypothetical protein 0.0116 0.0314 0.0342
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0033 0.0051 0.0199
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0277 0.0817 0.0817
Echinococcus multilocularis Transglutaminase 0.1058 0.326 0.3561
Echinococcus multilocularis lipoxygenase domain containing protein 0.0051 0.0108 0.0118
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0116 0.0314 0.0342
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Leishmania major pyruvate kinase 0.0045 0.0089 0.0343
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Schistosoma mansoni inositol monophosphatase 0.0033 0.0051 0.0089
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0031 0.0047 0.021
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Echinococcus multilocularis dna polymerase eta 0.0073 0.0178 0.0194
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0104 0.0275 0.03
Brugia malayi nuclear receptor RXR 0.0104 0.0275 0.03
Echinococcus granulosus histone lysine methyltransferase setb 0.0228 0.0664 0.0725
Trypanosoma brucei DNA topoisomerase ii 0.0038 0.0069 0.0265
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Loa Loa (eye worm) hypothetical protein 0.2612 0.8119 0.9156
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0085 0.0214 0.0234
Brugia malayi AMP-binding enzyme family protein 0.0217 0.0627 0.0685
Trypanosoma cruzi cdc2-related kinase 3 0.0073 0.0177 0.0685
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0038 0.0069 0.021
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0162 0.0456 0.1398
Echinococcus granulosus cyclin B3 1 0.0085 0.0215 0.0235
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0015 0.0066
Trichomonas vaginalis cyclin B3, putative 0.0021 0.0013 0.0033
Echinococcus granulosus neuropeptide s receptor 0.0378 0.1133 0.1237
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0064 0.0148 0.0573
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.005 0.0107 0.0414
Trichomonas vaginalis AGC family protein kinase 0.004 0.0074 0.0181
Echinococcus multilocularis cyclin y 0.0021 0.0013 0.0015
Schistosoma mansoni smad1 5 8 and 0.0024 0.0025 0.0044
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.0125 0.0339 0.1309
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0215 0.0525
Plasmodium falciparum ataxin-2 like protein, putative 0.0092 0.0238 0.1062
Loa Loa (eye worm) hypothetical protein 0.0077 0.019 0.0214
Brugia malayi hypothetical protein 0.0112 0.0299 0.0327
Echinococcus multilocularis neutral alpha glucosidase AB 0.003 0.0044 0.0048
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0092 0.0238 0.0581
Loa Loa (eye worm) haspin protein kinase 0.0035 0.0059 0.0066
Leishmania major 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0055 0.0135
Trypanosoma brucei heat shock protein, putative 0.0242 0.0706 0.2726
Echinococcus granulosus 3'partial|mitogen activated protein kinase kinase kinase 0.0085 0.0214 0.0234
Loa Loa (eye worm) hypothetical protein 0.0164 0.0463 0.0522
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0177 0.0306
Schistosoma mansoni RAR-like nuclear receptor 0.022 0.0639 0.1102
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0033 0.0054 0.0059
Leishmania major hypothetical protein, conserved 0.0038 0.0069 0.0265
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0177 0.0306
Echinococcus multilocularis cyclin dependent kinase 1 0.0073 0.0177 0.0194
Brugia malayi Isocitrate dehydrogenase 0.011 0.0293 0.032
Echinococcus multilocularis peregrin 0.0155 0.0433 0.0473
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0025 0.0028
Echinococcus multilocularis tissue type plasminogen activator 0.0021 0.0016 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0148 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0107 0.0262
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0097 0.0237
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0099 0.0259 0.1159
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0046 0.0095 0.0422
Brugia malayi RNA recognition motif domain containing protein 0.0401 0.1202 0.1313
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0128 0.035 0.0383
Echinococcus multilocularis heat shock protein 0.0242 0.0706 0.0771
Echinococcus granulosus cyclins 0.0085 0.0215 0.0235
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0064 0.0148 0.0148
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0031 0.0047 0.021
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.0033 0.0054 0.024
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0038 0.0069 0.0075
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0092 0.0238 0.0919
Schistosoma mansoni protein phosphatase-2b 0.0033 0.0054 0.0093
Loa Loa (eye worm) PHD-finger family protein 0.0142 0.0394 0.0444
Schistosoma mansoni regulator of G protein signaling 0.0077 0.019 0.0327
Schistosoma mansoni chromodomain helicase DNA binding protein 0.002 0.0011 0.0019
Brugia malayi Hsp90 protein 0.0147 0.0408 0.0446
Plasmodium falciparum pyruvate kinase 0.0045 0.0089 0.0397
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0064 0.0148 0.0662
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0148 0.0573
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0021 0.0016 0.007
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0228 0.0664 0.0725
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0056 0.0126 0.0562
Echinococcus multilocularis PHD finger protein rhinoceros 0.0142 0.0394 0.043
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Loa Loa (eye worm) hypothetical protein 0.022 0.0639 0.0721
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0064 0.0148 0.0162
Echinococcus granulosus GPCR family 2 0.0192 0.0548 0.0599
Toxoplasma gondii NADPH-glutathione reductase 0.0061 0.0141 0.0628
Toxoplasma gondii hypothetical protein 0.0239 0.0697 0.3115
Loa Loa (eye worm) hypothetical protein 0.0038 0.0069 0.0077
Toxoplasma gondii HEAT repeat-containing protein 0.0042 0.008 0.0359
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0092 0.0238 0.026
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0141 0.0543
Brugia malayi acetyltransferase, GNAT family protein 0.0171 0.0485 0.053
Schistosoma mansoni jumonji/arid domain-containing protein 0.0179 0.0509 0.0878
Loa Loa (eye worm) TK/ROR protein kinase 0.0025 0.0026 0.0029
Schistosoma mansoni smad1 5 8 and 0.0024 0.0025 0.0044
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0041 0.0079 0.0086
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0219 0.0635 0.1832
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0025 0.0029
Mycobacterium ulcerans glutaminase 0.062 0.1889 0.5795
Schistosoma mansoni hypothetical protein 0.0187 0.0534 0.0922
Schistosoma mansoni hypothetical protein 0.0142 0.0394 0.068
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.005 0.0107 0.0414
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0038 0.0069 0.0265
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0021 0.0013 0.006
Echinococcus granulosus L aminoadipate semialdehyde 0.0111 0.0297 0.0325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0044 0.0106
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0044 0.0108
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0013 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0084
Echinococcus multilocularis cyclins 0.0085 0.0215 0.0235
Brugia malayi hypothetical protein 0.0104 0.0274 0.0299
Brugia malayi Nuclear hormone receptor E75 0.0104 0.0275 0.03
Echinococcus granulosus survival motor neuron protein 1 0.0408 0.1225 0.1338
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0238 0.0581
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Loa Loa (eye worm) hypothetical protein 0.0073 0.0178 0.02
Loa Loa (eye worm) cyclin domain-containing protein 0.0021 0.0013 0.0015
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0029 0.0041 0.0118
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.003 0.0044 0.017
Schistosoma mansoni hypothetical protein 0.0104 0.0274 0.0472
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.005 0.0107 0.0414
Trypanosoma cruzi hypothetical protein, conserved 0.0092 0.0238 0.0919
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0148 0.0455
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0219 0.0635 0.2453
Echinococcus granulosus RUN 0.0051 0.0108 0.0118
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.022 0.0639 0.0698
Brugia malayi Protein kinase domain containing protein 0.0083 0.0209 0.0229
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0083 0.0209 0.0229
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0167 0.0471 0.2106
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0073 0.0178 0.0434
Giardia lamblia PHD finger protein 15 0.0142 0.0394 0.1208
Brugia malayi Regulator of G protein signaling domain containing protein 0.0077 0.019 0.0207
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0035 0.0059 0.0064
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0159 0.0446 0.0487
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0061 0.0141 0.0431
Trypanosoma brucei hypothetical protein, conserved 0.0092 0.0238 0.0919
Schistosoma mansoni phd/f-box containing protein 0.0046 0.0093 0.016
Leishmania major hypothetical protein, conserved 0.0021 0.0016 0.0061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0159 0.0446 0.0487
Mycobacterium ulcerans hypothetical protein 0.1058 0.326 1
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0092 0.0238 0.026
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0092 0.0238 0.0581
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0033 0.0054 0.0208
Echinococcus granulosus pyruvate kinase 0.0045 0.0089 0.0097
Entamoeba histolytica hypothetical protein 0.0021 0.0013 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.022 0.0639 0.0721
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.004 0.0074 0.0083
Leishmania major DNA topoisomerase ii 0.0038 0.0069 0.0265
Brugia malayi jmjC domain containing protein 0.0466 0.1406 0.1535
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Trypanosoma cruzi heat shock protein 85, putative 0.0242 0.0706 0.2726
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Loa Loa (eye worm) cyclin domain-containing protein 0.0262 0.077 0.0869
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.002 0.0078
Loa Loa (eye worm) glutathione reductase 0.0177 0.0502 0.0566
Schistosoma mansoni 6-phosphofructokinase 0.0078 0.0192 0.0332
Loa Loa (eye worm) apoptosis regulator protein 0.005 0.0107 0.012
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0277 0.0817 0.0817
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.1062
Giardia lamblia Kinase, PLK 0.0844 0.2589 0.7941
Mycobacterium tuberculosis Conserved hypothetical protein 0.0073 0.0178 0.0178
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0064 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0044 0.0086 0.0097
Trypanosoma cruzi trypanothione reductase, putative 0.0177 0.0502 0.1938
Echinococcus granulosus cyclin dependent kinase 1 0.0073 0.0177 0.0194
Trypanosoma cruzi pyruvate kinase 2, putative 0.0045 0.0089 0.0343
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.002 0.0078
Loa Loa (eye worm) hypothetical protein 0.0111 0.0297 0.0335
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0061 0.0141 0.0154
Schistosoma mansoni jumonji domain containing protein 0.0046 0.0093 0.016
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.005 0.0107 0.0184
Brugia malayi nuclear receptor NHR-67 0.0104 0.0275 0.03
Echinococcus multilocularis phd:f box containing protein 0.0046 0.0093 0.0101
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0013 0.0015
Entamoeba histolytica cyclin, domain containing protein 0.0021 0.0013 0.0051
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0015 0.0066
Echinococcus multilocularis jumonji domain containing 1A 0.0046 0.0093 0.0101
Leishmania major acetyl-CoA synthetase, putative 0.0064 0.0148 0.0573
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0064 0.0148 0.0167
Trypanosoma brucei polo-like protein kinase 0.0844 0.2589 1
Brugia malayi DNA topoisomerase I 0.0496 0.15 0.1638
Echinococcus multilocularis nuclear receptor nhr 48 0.0104 0.0275 0.03
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0038 0.0069 0.021
Schistosoma mansoni thyroid hormone receptor 0.022 0.0639 0.1102
Trypanosoma brucei heat shock protein, putative 0.0242 0.0706 0.2726
Entamoeba histolytica cyclin family protein 0.0085 0.0215 0.083
Plasmodium vivax phosphodiesterase gamma, putative 0.0092 0.0238 0.1062
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0159 0.0446 0.0503
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0152 0.0426 0.1644
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2589 0.6326
Echinococcus granulosus heat shock protein 90 0.0204 0.0586 0.064
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0033 0.0051 0.0702
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0107 0.0262
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0247 0.0723 0.079
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0107 0.0262
Loa Loa (eye worm) Smad1 0.0024 0.0025 0.0029
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0038 0.0069 0.0307
Schistosoma mansoni Tr4/Tr2 (homologue) 0.022 0.0639 0.1102
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Plasmodium falciparum JmjC domain-containing protein, putative 0.0046 0.0093 0.0414
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0075 0.0289
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0092 0.0238 0.0581
Giardia lamblia Kinase, CAMK CAMKL 0.004 0.0074 0.0227
Echinococcus multilocularis cyclin dependent kinase 0.0073 0.0177 0.0194
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0104 0.0274 0.0299
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0331 0.0986 0.2409
Echinococcus granulosus Cyclin L1 0.0021 0.0013 0.0015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0114 0.0196
Loa Loa (eye worm) hypothetical protein 0.022 0.0639 0.0721
Brugia malayi Nuclear hormone receptor family member nhr-25 0.022 0.0639 0.0698
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.002 0.009
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0141 0.1916
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0061 0.0141 0.0628
Schistosoma mansoni alpha-glucosidase 0.0118 0.0317 0.0548
Trichomonas vaginalis cyclin D, putative 0.0085 0.0215 0.0525
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0064 0.0148 0.0573
Trichomonas vaginalis DNA topoisomerase II, putative 0.0038 0.0069 0.0168
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0061 0.0141 0.0154
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0371 0.111 0.4288
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0844 0.2589 0.292
Brugia malayi AMP-binding enzyme family protein 0.0217 0.0627 0.0685
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Brugia malayi nuclear receptor NHR-88 0.0104 0.0275 0.03
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0082 0.0205 0.0224
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0044 0.017
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0217 0.0627 0.181
Trichomonas vaginalis cyclin B, putative 0.0021 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0051 0.0108 0.0121
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.002 0.0078
Brugia malayi kinase, mitochondrial precursor 0.0038 0.0069 0.0075
Loa Loa (eye worm) hypothetical protein 0.0116 0.0314 0.0354
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Loa Loa (eye worm) hypothetical protein 0.0112 0.0299 0.0337
Schistosoma mansoni hypothetical protein 0.0074 0.0182 0.0314
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0104 0.0275 0.031
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.004 0.0074 0.0286
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0092 0.0238 0.1062
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0331 0.0986 0.3808
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Echinococcus multilocularis Polycystic kidney disease protein 0.0051 0.0108 0.0118
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Plasmodium falciparum LCCL domain-containing protein 0.0051 0.0108 0.0481
Brugia malayi PXA domain containing protein 0.0077 0.019 0.0207
Brugia malayi orphan nuclear receptor NR2E1 0.0104 0.0275 0.03
Echinococcus multilocularis pyruvate kinase 0.0035 0.0059 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0074 0.0181
Toxoplasma gondii heat shock protein 90, putative 0.0242 0.0706 0.3153
Loa Loa (eye worm) jmjC domain-containing protein 0.0294 0.0867 0.0978
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0033 0.0051 0.0126
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.013 0.0355 0.0388
Giardia lamblia Cyclin A 0.0085 0.0215 0.0659
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0044 0.0108
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1164 0.359 0.4048
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0125 0.0341 0.0589
Brugia malayi Nuclear hormone receptor-like 1 0.0116 0.0314 0.0342
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0073 0.0178 0.0194
Trichomonas vaginalis cyclins, putative 0.0164 0.0463 0.1131
Echinococcus multilocularis survival motor neuron protein 1 0.0408 0.1225 0.1338
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0023
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0064 0.0148 0.0455
Entamoeba histolytica hypothetical protein 0.0035 0.0059 0.0227
Echinococcus granulosus geminin 0.1869 0.5795 0.6329
Echinococcus granulosus regulator of G protein signaling 3 0.0077 0.019 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0013 0.0033
Trichomonas vaginalis cyclin B, putative 0.0164 0.0463 0.1131
Loa Loa (eye worm) hypothetical protein 0.0092 0.0238 0.0268
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.002 0.009
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0128 0.035 0.035
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0152 0.0426 0.0465
Schistosoma mansoni DNA topoisomerase type I 0.0496 0.15 0.2588
Brugia malayi Thioredoxin family protein 0.1058 0.326 0.3561
Toxoplasma gondii hypothetical protein 0.0239 0.0697 0.3115
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0092 0.0238 0.0919
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0159 0.0446 0.0769
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0104 0.0275 0.0671
Plasmodium falciparum heat shock protein 90, putative 0.0732 0.2238 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0046 0.0093 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2589 0.6326
Brugia malayi Nuclear hormone receptor E75 0.0104 0.0275 0.03
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0092 0.0238 0.026
Echinococcus multilocularis ecdysone induced protein 78C 0.022 0.0639 0.0698
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.0919
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0002 0.0008
Trichomonas vaginalis cyclin B, putative 0.0164 0.0463 0.1131
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0046 0.0093 0.0358
Trypanosoma cruzi ISWI complex protein 0.0055 0.0122 0.0471
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 7 0.0085 0.0214 0.0234
Loa Loa (eye worm) hypothetical protein 0.022 0.0639 0.0721
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0074 0.0181
Brugia malayi serine/threonine-protein kinase plk-2 0.0844 0.2589 0.2828
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0095 0.0422
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0038 0.0069 0.0307
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0466 0.1406 0.1535
Loa Loa (eye worm) hypothetical protein 0.0162 0.0456 0.0514
Brugia malayi Probable DNA topoisomerase II 0.0038 0.0069 0.0075
Entamoeba histolytica hypothetical protein 0.0034 0.0056 0.0215
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.0125 0.0339 0.1309
Brugia malayi glutathione reductase 0.0177 0.0502 0.0548
Loa Loa (eye worm) endoplasmin 0.0242 0.0706 0.0796
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0077 0.019 0.0207
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0038 0.0069 0.0168
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0251 0.0734 1
Schistosoma mansoni cyclin B3 0.0262 0.077 0.1329
Onchocerca volvulus 0.0064 0.0148 0.0362
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0262 0.077 0.0841
Schistosoma mansoni hypothetical protein 0.0035 0.0059 0.0102
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0077 0.019 0.0214
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0025 0.0029
Chlamydia trachomatis replicative DNA helicase 0.0251 0.0734 1
Echinococcus multilocularis chromobox protein 1 0.0078 0.0194 0.0212
Loa Loa (eye worm) TOPoisomerase family member 0.0038 0.0069 0.0077
Schistosoma mansoni hypothetical protein 0.1869 0.5795 1
Echinococcus granulosus 5'partial|3'partial|mitogen activated protein kinase kinase kinase 0.0085 0.0214 0.0234
Trypanosoma brucei heat shock protein, putative 0.0242 0.0706 0.2726
Echinococcus granulosus cyclin B 0.0164 0.0463 0.0505
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Schistosoma mansoni loxhd1 0.0051 0.0108 0.0186
Entamoeba histolytica hypothetical protein 0.0077 0.019 0.0733
Loa Loa (eye worm) hypothetical protein 0.0151 0.0422 0.0475
Echinococcus granulosus pyruvate kinase 0.0023 0.0021 0.0023
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0092 0.0238 0.0919
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.002 0.0078
Schistosoma mansoni chromobox protein 0.0078 0.0194 0.0335
Echinococcus multilocularis cyclins 0.0085 0.0215 0.0235
Schistosoma mansoni coup transcription factor 0.022 0.0639 0.1102
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Echinococcus multilocularis neuropeptide receptor A26 0.0378 0.1133 0.1237
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0192 0.0548 0.0599
Brugia malayi RNA, U transporter 1 0.0119 0.0322 0.0352
Echinococcus granulosus expressed protein 0.1498 0.4633 0.5061
Schistosoma mansoni smad 0.0024 0.0025 0.0044
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0038 0.0069 0.0069
Plasmodium vivax pyruvate kinase 2, putative 0.0023 0.0021 0.0093
Schistosoma mansoni retinoic acid receptor RXR 0.022 0.0639 0.1102
Loa Loa (eye worm) nuclear hormone receptor 0.0104 0.0275 0.031
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.0044 0.0108
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0033 0.0051 0.023
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0167
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.005 0.0107 0.0414
Echinococcus multilocularis FTZ F1 alpha 0.022 0.0639 0.0698
Loa Loa (eye worm) hypothetical protein 0.0046 0.0093 0.0105
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.035 0.1075
Plasmodium falciparum MO15-related protein kinase 0.0536 0.1625 0.726
Loa Loa (eye worm) STAT protein 0.0132 0.0364 0.041
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0152 0.0426 0.1644
Leishmania major DNA polymerase eta, putative 0.0023 0.002 0.0078
Echinococcus granulosus histone acetyltransferase KAT2B 0.0056 0.0126 0.0137
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0092 0.0238 0.026
Brugia malayi F/Y-rich N-terminus family protein 0.006 0.0135 0.0148
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0466 0.1406 0.1535
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0136 0.0373 0.5087
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0044 0.0106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0228 0.0664 0.1146
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Schistosoma mansoni hypothetical protein 0.0055 0.0122 0.021
Trypanosoma cruzi cyclin 6, putative 0.0164 0.0463 0.1788
Loa Loa (eye worm) hypothetical protein 0.2851 0.8867 1
Mycobacterium ulcerans 6-phosphofructokinase 0.0078 0.0192 0.0589
Loa Loa (eye worm) hypothetical protein 0.022 0.0639 0.0721
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0045 0.009 0.0098
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0013 0.0015
Onchocerca volvulus 0.0104 0.0275 0.0671
Schistosoma mansoni 6-phosphofructokinase 0.0078 0.0192 0.0332
Brugia malayi Bromodomain containing protein 0.0155 0.0433 0.0473
Echinococcus multilocularis cyclin A3 4 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.022 0.0639 0.0721
Mycobacterium tuberculosis Conserved hypothetical protein 0.1058 0.326 0.326
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Trichomonas vaginalis inositol monophosphatase, putative 0.0033 0.0051 0.0126
Brugia malayi cyclin-dependent kinase 7 homolog 0.004 0.0074 0.0081
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0038 0.0069 0.0069
Loa Loa (eye worm) 6-phosphofructokinase 0.0078 0.0192 0.0217
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.004 0.0074 0.0331
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.022 0.0639 0.0698
Onchocerca volvulus 0.0034 0.0057 0.0139
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0219 0.0635 0.0635
Onchocerca volvulus 0.018 0.0511 0.125
Echinococcus multilocularis cyclin dependent kinase 1 0.0073 0.0177 0.0194
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0116 0.0314 0.0541
Schistosoma mansoni hypothetical protein 0.0021 0.0013 0.0023
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.002 0.0078
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.013 0.0355 0.0388
Schistosoma mansoni thyroid hormone receptor 0.022 0.0639 0.1102
Trypanosoma cruzi DNA polymerase eta, putative 0.0073 0.0178 0.0686
Echinococcus granulosus cyclin G2 0.0021 0.0013 0.0015
Brugia malayi Cyclin C 0.0021 0.0013 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trypanosoma cruzi cdc2-related kinase 3 0.0073 0.0177 0.0685
Schistosoma mansoni cyclin B 0.0164 0.0463 0.0799
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0064 0.0148 0.0162
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0025 0.0028
Mycobacterium tuberculosis Probable dehydrogenase 0.0403 0.1209 0.1209
Echinococcus granulosus zinc finger protein 0.0075 0.0183 0.02
Brugia malayi photoreceptor-specific nuclear receptor 0.022 0.0639 0.0698
Echinococcus granulosus Smad4 0.0024 0.0025 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0092 0.0238 0.0919
Echinococcus granulosus importin subunit beta 1 0.0042 0.008 0.0088
Loa Loa (eye worm) oxidoreductase 0.0064 0.0148 0.0167
Echinococcus granulosus microtubule associated protein 2 0.1621 0.5019 0.5482
Brugia malayi Protein kinase domain containing protein 0.0073 0.0177 0.0194
Echinococcus granulosus endoplasmin 0.0219 0.0635 0.0694
Onchocerca volvulus 0.0021 0.0016 0.0038
Brugia malayi A-kinase anchor protein 10, precursor 0.0077 0.019 0.0207
Trypanosoma brucei Heat shock protein 83, putative 0.0242 0.0706 0.2726
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0092 0.0238 0.0729
Brugia malayi Cell division protein kinase 2 0.004 0.0074 0.0081
Echinococcus multilocularis cyclin dependent kinase 9 0.004 0.0074 0.0081
Echinococcus granulosus Transglutaminase 0.1058 0.326 0.3561
Trypanosoma cruzi cyclin 9, putative 0.0021 0.0013 0.0051
Echinococcus granulosus neutral alpha glucosidase AB 0.003 0.0044 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.005 0.0107 0.0414
Schistosoma mansoni transcription factor LCR-F1 0.0104 0.0274 0.0472
Trichomonas vaginalis cyclin B, putative 0.0164 0.0463 0.1131
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0164 0.0463 0.1788
Leishmania major hypothetical protein, conserved 0.0092 0.0238 0.0918
Loa Loa (eye worm) cyclin domain-containing protein 0.0021 0.0013 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.018 0.0511 0.0883
Onchocerca volvulus 0.0064 0.0148 0.0362
Leishmania major mitotic cyclin, putative 0.0021 0.0013 0.0051
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0251 0.0734 0.2251
Echinococcus multilocularis cyclins 0.0085 0.0215 0.0235
Trichomonas vaginalis set domain proteins, putative 0.1325 0.4093 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0247 0.0723 0.079
Echinococcus granulosus thyroid hormone receptor alpha 0.0104 0.0275 0.03
Leishmania major cAMP-specific phosphodiesterase, putative 0.0092 0.0238 0.0919
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.005 0.0107 0.0185
Echinococcus granulosus cyclins 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0092 0.0238 0.0268
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0031 0.0047 0.0642
Trichomonas vaginalis cyclin A, putative 0.0164 0.0463 0.1131
Loa Loa (eye worm) hypothetical protein 0.0244 0.0712 0.0803
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0021 0.0013 0.0015
Brugia malayi glutaminase DH11.1 0.062 0.1889 0.2064
Loa Loa (eye worm) haspin protein kinase 0.004 0.0074 0.0083
Plasmodium vivax endoplasmin, putative 0.0242 0.0706 0.3153
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0092 0.0238 0.041
Loa Loa (eye worm) hypothetical protein 0.0076 0.0188 0.0212
Brugia malayi nuclear hormone receptor family member nhr-6 0.0104 0.0275 0.03
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0015 0.0066
Entamoeba histolytica heat shock protein 90, putative 0.0242 0.0706 0.2726
Trichomonas vaginalis cyclins, putative 0.0164 0.0463 0.1131
Schistosoma mansoni Replicative DNA helicase 0.0251 0.0734 0.1266
Schistosoma mansoni hypothetical protein 0.0046 0.0095 0.0163
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0086 0.0265
Schistosoma mansoni nuclear hormone receptor 0.0104 0.0275 0.0474
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Echinococcus granulosus regulator of G protein signaling 7 0.0077 0.019 0.0207
Loa Loa (eye worm) pyruvate kinase-PB 0.0031 0.0047 0.0053
Mycobacterium tuberculosis Probable two component sensor kinase 0.0038 0.0069 0.0069
Echinococcus granulosus FTZ F1 alpha 0.022 0.0639 0.0698
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0051 0.0199
Brugia malayi heat shock protein 90 0.0242 0.0706 0.0771
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0217 0.0627 0.181
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0002 0.0008
Onchocerca volvulus Serine\/threonine kinase homolog 0.0844 0.2589 0.6326
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0064 0.0148 0.0455
Trypanosoma cruzi CYC2-like cyclin, putative 0.0164 0.0463 0.1788
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0038 0.0069 0.021
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.022 0.0639 0.0698
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0033 0.0054 0.0059
Chlamydia trachomatis DNA gyrase subunit B 0.0038 0.0069 0.0935
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0073 0.0178 0.0178
Onchocerca volvulus 0.0112 0.0299 0.0731
Echinococcus multilocularis geminin 0.1869 0.5795 0.6329
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0034 0.0056 0.0136
Echinococcus granulosus Nuclear hormone receptor HR96 0.0104 0.0275 0.03
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0536 0.1625 0.726
Echinococcus granulosus Pfam-B_8186 domain containing protein 0.0035 0.0059 0.0064
Trichomonas vaginalis receptor histidine kinase, putative 0.0038 0.0069 0.0168
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0038 0.0069 0.0198
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Echinococcus multilocularis G1:S specific cyclin D1 0.0021 0.0013 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2589 0.6326
Loa Loa (eye worm) PHD-finger family protein 0.0074 0.0182 0.0205
Brugia malayi AF-10 protein 0.0046 0.0095 0.0103
Brugia malayi PHD-finger family protein 0.0094 0.0243 0.0265
Trypanosoma cruzi DNA repair protein, putative 0.0042 0.008 0.0308
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.011 0.0293 0.113
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0046 0.0095 0.0365
Echinococcus multilocularis dna polymerase kappa 0.0073 0.0178 0.0194
Echinococcus granulosus JmjC domain containing protein 4 0.0046 0.0093 0.0101
Onchocerca volvulus Alhambra homolog 0.0142 0.0394 0.0962
Giardia lamblia Hypothetical protein 0.0021 0.0013 0.0041
Brugia malayi isocitrate dehydrogenase 0.011 0.0293 0.032
Echinococcus granulosus tissue type plasminogen activator 0.0021 0.0016 0.0017
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0116 0.0314 0.0541
Onchocerca volvulus 0.1058 0.326 0.7966
Loa Loa (eye worm) glutaminase 2 0.062 0.1889 0.2131
Loa Loa (eye worm) CYL-1 protein 0.0021 0.0013 0.0015
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.011 0.0293 0.0293
Trichomonas vaginalis AGC family protein kinase 0.004 0.0074 0.0181
Echinococcus multilocularis X box binding protein 1 0.0187 0.0534 0.0583
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0002 0.0002
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0021 0.0013 0.006
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0033 0.0054 0.0208
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0148 0.0148
Plasmodium vivax cyclin 4, putative 0.0021 0.0013 0.006
Loa Loa (eye worm) CHromoDomain protein family member 0.002 0.0011 0.0012
Echinococcus multilocularis cyclin dependent kinase 5 0.0073 0.0177 0.0194
Echinococcus multilocularis Regulator of G protein signaling 20 0.0077 0.019 0.0207
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.005 0.0107 0.0116
Echinococcus granulosus tar DNA binding protein 0.0401 0.1202 0.1313
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0033 0.0054 0.0208
Loa Loa (eye worm) hypothetical protein 0.005 0.0107 0.012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0061
Loa Loa (eye worm) hypothetical protein 0.0331 0.0986 0.1112
Entamoeba histolytica pyruvate kinase, putative 0.0031 0.0047 0.018
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0029 0.0041 0.0041
Schistosoma mansoni microtubule-associated protein tau 0.1621 0.5019 0.8662
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0092 0.0238 0.041
Mycobacterium ulcerans putative regulatory protein 0.0239 0.0697 0.2138
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0033 0.0054 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0205 0.0354
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0171 0.0485 0.0837
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0082 0.0205 0.0231
Schistosoma mansoni hypothetical protein 0.0021 0.0013 0.0023
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0038 0.0069 0.0069
Loa Loa (eye worm) heat shock protein 75 0.0147 0.0408 0.046
Brugia malayi Steroid receptor seven-up type 2 0.022 0.0639 0.0698
Entamoeba histolytica cyclin, domain containing protein 0.0021 0.0013 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Brugia malayi chromobox protein homolog 3 0.0044 0.0086 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0084
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0073 0.0177 0.02
Leishmania major pyruvate kinase 0.0045 0.0089 0.0343
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0045 0.009 0.0098
Entamoeba histolytica phosphofructokinase, putative 0.0078 0.0192 0.0742
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0147 0.0408 0.0446
Plasmodium vivax topoisomerase I, putative 0.0496 0.15 0.6701
Brugia malayi Pyruvate kinase, M2 isozyme 0.0045 0.0089 0.0097
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0033 0.0054 0.0208
Loa Loa (eye worm) hypothetical protein 0.0033 0.0052 0.0059
Schistosoma mansoni hypothetical protein 0.0041 0.0079 0.0136
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0104 0.0275 0.0671
Echinococcus multilocularis importin subunit beta 1 0.0042 0.008 0.0088
Brugia malayi jmjC domain containing protein 0.0046 0.0093 0.0101
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0064 0.0148 0.0573
Schistosoma mansoni alpha glucosidase 0.003 0.0044 0.0076
Trypanosoma cruzi DNA topoisomerase II, putative 0.0038 0.0069 0.0265
Giardia lamblia NADH oxidase lateral transfer candidate 0.0061 0.0141 0.0431
Mycobacterium ulcerans pyruvate kinase 0.0045 0.0089 0.0273
Brugia malayi Calcitonin receptor-like protein seb-1 0.0605 0.1843 0.2013
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0056 0.0126 0.0562
Echinococcus granulosus Nuclear hormone receptor HR96 0.0104 0.0275 0.03
Entamoeba histolytica cell division protein kinase 2, putative 0.0108 0.0287 0.1109
Mycobacterium ulcerans putative transglutaminase-like protein 0.1058 0.326 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.022 0.0639 0.0698
Schistosoma mansoni protein phosphatase 2C 0.0047 0.0095 0.0164
Plasmodium falciparum endoplasmin, putative 0.0169 0.0479 0.214
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Plasmodium falciparum phosphodiesterase gamma, putative 0.0092 0.0238 0.1062
Trichomonas vaginalis cyclin B3, putative 0.0085 0.0215 0.0525
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0002 0.0008
Echinococcus multilocularis transcription factor Dp 1 0.0088 0.0225 0.0246
Echinococcus granulosus chromobox protein 1 0.0078 0.0194 0.0212
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0055 0.0121 0.0121
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0403 0.1209 0.1209
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0061 0.0141 0.0543
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0021 0.0015 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0067 0.0163
Echinococcus granulosus cyclins 0.0085 0.0215 0.0235
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0038 0.0069 0.0168
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0178 0.0194
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0015 0.0066
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0331 0.0986 0.1077
Toxoplasma gondii hypothetical protein 0.0064 0.0151 0.0674
Echinococcus multilocularis heat shock protein 90 0.0204 0.0586 0.064
Plasmodium falciparum DNA gyrase subunit B 0.0038 0.0069 0.0307
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0219 0.0635 0.8652
Leishmania major 4-coumarate:coa ligase-like protein 0.0217 0.0627 0.2422
Loa Loa (eye worm) PXA domain-containing protein 0.0077 0.019 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0075 0.0183
Echinococcus multilocularis axis inhibition protein axin 0.0077 0.019 0.0207
Echinococcus granulosus lysosomal alpha glucosidase 0.0137 0.0377 0.0412
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0141 0.0543
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0605 0.1843 0.2013
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0116 0.0314 0.0342
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0077 0.019 0.0327
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0046 0.0093 0.0414
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0159 0.0446 0.0769
Brugia malayi MH2 domain containing protein 0.0358 0.1069 0.1168
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0038 0.0069 0.0935
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0844 0.2589 1
Echinococcus granulosus serine:threonine protein kinase NLK 0.004 0.0074 0.0081
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0038 0.0069 0.021
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0092 0.0238 0.0581
Leishmania major phosphopantetheinyl transferase-like protein 0.0031 0.0047 0.0182
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0064 0.0148 0.0455
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0075 0.0183
Plasmodium vivax DNA topoisomerase II, putative 0.0038 0.0069 0.0307
Schistosoma mansoni steroid hormone receptor ad4bp 0.022 0.0639 0.1102
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0141 0.0543
Schistosoma mansoni hypothetical protein 0.005 0.0107 0.0184
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0064 0.0148 0.0662
Trypanosoma cruzi polo-like protein kinase, putative 0.0844 0.2589 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0082 0.0205 0.0224
Trypanosoma cruzi DNA topoisomerase II, putative 0.0038 0.0069 0.0265
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0084
Brugia malayi hypothetical protein 0.0408 0.1225 0.1338
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0013 0.0015
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0178 0.0194
Trichomonas vaginalis heat shock protein, putative 0.0242 0.0706 0.1724
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0064 0.0148 0.0573
Loa Loa (eye worm) cyclin domain-containing protein 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0162 0.0456 0.0514
Echinococcus granulosus cyclin b3 0.0085 0.0215 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0067 0.0163
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Echinococcus granulosus dna polymerase kappa 0.0073 0.0178 0.0194
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Plasmodium vivax glutathione reductase, putative 0.0177 0.0502 0.2241
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0078 0.0192 0.2618
Brugia malayi Glycosyl hydrolases family 31 protein 0.0137 0.0377 0.0412
Trichomonas vaginalis receptor histidine kinase, putative 0.0038 0.0069 0.0168
Leishmania major hypothetical protein, conserved 0.0046 0.0093 0.0358
Echinococcus granulosus ribosomal protein L19 0.0021 0.0015 0.0016
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.022 0.0639 0.0721
Loa Loa (eye worm) hypothetical protein 0.0116 0.0314 0.0354
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.0044 0.0108
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0104 0.0275 0.03
Mycobacterium leprae Probable pyruvate kinase PykA 0.0045 0.0089 0.0256
Echinococcus granulosus transient receptor potential cation channel 0.0345 0.1028 0.1123
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0064 0.0148 0.0455
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0077 0.019 0.0207
Trypanosoma cruzi cdc2-related kinase 1 0.0073 0.0177 0.0685
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0015 0.0036
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0002 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0153 0.0428 0.0428
Echinococcus granulosus axis inhibition protein axin 0.0077 0.019 0.0207
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0051 0.0199
Toxoplasma gondii kringle domain-containing protein 0.0021 0.0016 0.007
Brugia malayi hypothetical protein 0.0104 0.0275 0.03
Schistosoma mansoni cyclin d 0.0021 0.0013 0.0023
Trichomonas vaginalis AGC family protein kinase 0.004 0.0074 0.0181
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.022 0.0639 0.0698
Schistosoma mansoni endoplasmin 0.0242 0.0706 0.1218
Brugia malayi Nuclear hormone receptor family member nhr-40 0.022 0.0639 0.0698
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0085 0.0214 0.0234
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0092 0.0238 0.1062
Echinococcus granulosus neuropeptide receptor A26 0.0378 0.1133 0.1237
Toxoplasma gondii LsmAD domain-containing protein 0.0092 0.0238 0.1062
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.005 0.0107 0.0117
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0083 0.0209 0.0229
Trypanosoma brucei mitotic cyclin 0.0021 0.0013 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0015 0.0036
Brugia malayi hypothetical protein 0.006 0.0135 0.0148
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0038 0.0069 0.0265
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0021 0.0013 0.0015
Echinococcus multilocularis DNA topoisomerase 1 0.0496 0.15 0.1638
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.002 0.0078
Trichomonas vaginalis AGC family protein kinase 0.004 0.0074 0.0181
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0078 0.0192 0.0192
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0021 0.0013 0.0015
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0033 0.0051 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.019 0.0464
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0228 0.0664 0.1146
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0002 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0013 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.022 0.0639 0.0698
Leishmania major DNA topoisomerase type IB small subunit 0.0125 0.0339 0.1309
Trichomonas vaginalis pyruvate kinase, putative 0.0045 0.0089 0.0217
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0038 0.0069 0.0075
Mycobacterium ulcerans heat shock protein 90 0.0219 0.0635 0.1948
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0064 0.0148 0.0148
Entamoeba histolytica protein kinase domain containing protein 0.004 0.0074 0.0286
Brugia malayi AMP-binding enzyme family protein 0.0064 0.0148 0.0162
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0046 0.0095 0.0422
Chlamydia trachomatis recombinase RecA 0.0136 0.0373 0.5087
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0153 0.0428 0.0428
Trypanosoma cruzi heat shock protein, putative 0.0147 0.0408 0.1577
Echinococcus granulosus mitogen activated protein kinase 15 0.004 0.0074 0.0081
Brugia malayi phosphofructokinase 0.0078 0.0192 0.021
Leishmania major serine/threonine kinase-like protein, putative 0.004 0.0074 0.0286
Schistosoma mansoni Cyclin fold protein 0.0021 0.0013 0.0023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0141 0.0543
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0031 0.0047 0.0642
Trichomonas vaginalis AGC family protein kinase 0.004 0.0074 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0092 0.0238 0.0919
Trichomonas vaginalis sucrase-isomaltase, putative 0.003 0.0044 0.0108
Echinococcus granulosus cyclin dependent kinase 0.0073 0.0177 0.0194
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0073 0.0178 0.0194
Plasmodium falciparum phosphodiesterase delta, putative 0.0092 0.0238 0.1062
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0148 0.0455
Leishmania major importin beta-1 subunit, putative 0.0034 0.0056 0.0215
Brugia malayi conserved hypotetical protein 0.0104 0.0275 0.03
Loa Loa (eye worm) hypothetical protein 0.0192 0.0548 0.0618
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Toxoplasma gondii Hsp90 domain-containing protein 0.0732 0.2238 1
Toxoplasma gondii hypothetical protein 0.0021 0.0013 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0043 0.0104
Chlamydia trachomatis pyruvate kinase 0.0045 0.0089 0.1211
Echinococcus granulosus transcription factor Dp 1 0.0088 0.0225 0.0246
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0061 0.0141 0.0543
Mycobacterium ulcerans putative regultory protein 0.0038 0.0069 0.021
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0171 0.0485 0.053
Schistosoma mansoni zinc finger protein 0.0104 0.0275 0.0474
Brugia malayi PXA domain containing protein 0.0077 0.019 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.019 0.0464
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0021 0.0015 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.0697 0.1703
Echinococcus granulosus heat shock protein 90 0.0242 0.0706 0.0771
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.011 0.0293 0.0505
Schistosoma mansoni DNA topoisomerase type I 0.0371 0.111 0.1916
Plasmodium vivax ataxin-2 like protein, putative 0.0092 0.0238 0.1062
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0331 0.0986 0.1077
Loa Loa (eye worm) doublecortin family protein 0.0051 0.0108 0.0121
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0177 0.0433
Trichomonas vaginalis cyclin B, putative 0.0164 0.0463 0.1131
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.0697 0.1703
Echinococcus granulosus cyclin t1 0.0021 0.0013 0.0015
Onchocerca volvulus 0.0051 0.0108 0.0263
Schistosoma mansoni bromodomain containing protein 0.0019 0.001 0.0017
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0194 0.0474
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.019 0.0464
Trichomonas vaginalis cyclin B, putative 0.0021 0.0013 0.0033
Plasmodium falciparum GAF domain-related protein, putative 0.0239 0.0697 0.3115
Brugia malayi Kringle domain containing protein 0.0021 0.0016 0.0017
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.003 0.0044 0.0197
Echinococcus multilocularis cyclin b3 0.0085 0.0215 0.0235
Echinococcus multilocularis lysine specific demethylase 6a 0.0046 0.0093 0.0101
Echinococcus multilocularis cyclins 0.0085 0.0215 0.0235
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0141 0.1916
Echinococcus multilocularis cyclin G2 0.0021 0.0013 0.0015
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Schistosoma mansoni cyclin G2 0.0021 0.0013 0.0023
Trichomonas vaginalis cyclins, putative 0.01 0.0261 0.0638
Loa Loa (eye worm) hypothetical protein 0.0053 0.0116 0.0131
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.002 0.0078
Loa Loa (eye worm) thioredoxin reductase 0.0177 0.0502 0.0566
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0038 0.0069 0.021
Loa Loa (eye worm) hypothetical protein 0.0077 0.019 0.0214
Trichomonas vaginalis heat shock protein, putative 0.0169 0.0479 0.1171
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0031 0.0047 0.0144
Loa Loa (eye worm) hypothetical protein 0.0104 0.0275 0.031
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0148 0.0455
Trichomonas vaginalis CMGC family protein kinase 0.0073 0.0177 0.0433
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0075 0.0289
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0092 0.0238 0.026
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0061 0.0141 0.0628
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Brugia malayi Nuclear hormone receptor family member nhr-41 0.022 0.0639 0.0698
Trichomonas vaginalis CAMK family protein kinase 0.0419 0.1259 0.3077
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0148 0.0455
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0074 0.0181
Echinococcus multilocularis regulator of G protein signaling 3 0.0077 0.019 0.0207
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0038 0.0069 0.0265
Echinococcus multilocularis cyclin G2 0.0021 0.0013 0.0015
Trypanosoma brucei cdc2-related kinase 1 0.0073 0.0177 0.0685
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0046 0.0113
Schistosoma mansoni apoptosis regulator bax 0.005 0.0107 0.0184
Trypanosoma cruzi heat shock protein 85, putative 0.0204 0.0586 0.2265
Loa Loa (eye worm) nuclear receptor NHR-67 0.0104 0.0275 0.031
Brugia malayi jmjC domain containing protein 0.0046 0.0093 0.0101
Mycobacterium leprae Conserved hypothetical protein 0.1058 0.326 0.9407
Brugia malayi jmjC domain containing protein 0.0179 0.0509 0.0556
Brugia malayi Cyclin, N-terminal domain containing protein 0.0164 0.0463 0.0505
Plasmodium vivax JmjC domain containing protein 0.0046 0.0093 0.0414
Schistosoma mansoni tar DNA-binding protein 0.0401 0.1202 0.2075
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0141 0.0543
Giardia lamblia Hypothetical protein 0.0092 0.0238 0.0729
Echinococcus multilocularis cyclin y 0.0021 0.0013 0.0015
Brugia malayi Cyclin, N-terminal domain containing protein 0.0262 0.077 0.0841
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0021 0.0015 0.0036
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0152 0.0426 0.0734
Trypanosoma brucei glucosidase, putative 0.003 0.0044 0.017
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0061 0.0141 0.0628
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0053 0.0114 0.0125
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0064 0.0148 0.0573
Trypanosoma cruzi Heat shock protein 83, putative 0.0242 0.0706 0.2726
Loa Loa (eye worm) MH2 domain-containing protein 0.0358 0.1069 0.1206
Schistosoma mansoni pyruvate kinase 0.0023 0.0021 0.0036
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0033 0.0054 0.0208
Onchocerca volvulus Pyruvate kinase homolog 0.0045 0.0089 0.0217
Loa Loa (eye worm) hypothetical protein 0.0038 0.0069 0.0077
Loa Loa (eye worm) hypothetical protein 0.0605 0.1843 0.2078
Trypanosoma cruzi cdc2-related kinase 1 0.0073 0.0177 0.0685
Loa Loa (eye worm) bromodomain containing protein 0.0068 0.0161 0.0182
Plasmodium vivax heat shock protein, putative 0.0732 0.2238 1
Echinococcus granulosus regulator of G protein signaling 3 0.0077 0.019 0.0207
Loa Loa (eye worm) steroid hormone receptor 0.022 0.0639 0.0721
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0092 0.0238 0.026
Trichomonas vaginalis glutaminase, putative 0.062 0.1889 0.4616
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0047 0.0182
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.005 0.0107 0.0414
Brugia malayi Protein kinase domain containing protein 0.0025 0.0026 0.0028
Echinococcus granulosus snurportin 1 0.0448 0.135 0.1475
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0141 0.0543
Echinococcus granulosus nuclear receptor 2DBD gamma 0.022 0.0639 0.0698
Brugia malayi hypothetical protein 0.0137 0.0377 0.0412
Mycobacterium tuberculosis Conserved protein 0.0038 0.0069 0.0069
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0178 0.0686
Trichomonas vaginalis protein kinase atmrk1, putative 0.004 0.0074 0.0181
Plasmodium falciparum DNA topoisomerase 2 0.0038 0.0069 0.0307
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.2943 0.9155 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0179 0.0509 0.0878
Brugia malayi hypothetical protein 0.0116 0.0314 0.0342
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Plasmodium falciparum ataxin-2 like protein, putative 0.0092 0.0238 0.1062
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.005 0.0107 0.0116
Trypanosoma brucei trypanothione reductase 0.0177 0.0502 0.1938
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Giardia lamblia Pms1-like protein 0.0038 0.0069 0.021
Trypanosoma brucei ISWI complex protein 0.0055 0.0122 0.0471
Mycobacterium ulcerans DNA gyrase subunit B 0.0038 0.0069 0.021
Giardia lamblia Hypothetical protein 0.1058 0.326 1
Trichomonas vaginalis CAMK family protein kinase 0.0844 0.2589 0.6326
Trypanosoma brucei cdc2-related kinase 3 0.0073 0.0177 0.0685
Trypanosoma cruzi heat shock protein 85, putative 0.0242 0.0706 0.2726
Plasmodium falciparum protein kinase 5 0.0073 0.0177 0.0793
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0031 0.0047 0.021
Onchocerca volvulus Pyruvate kinase homolog 0.0045 0.0089 0.0217
Onchocerca volvulus 0.0021 0.0013 0.0033
Trypanosoma brucei heat shock protein, putative 0.0242 0.0706 0.2726
Leishmania major heat shock protein 83-1 0.0242 0.0706 0.2726
Loa Loa (eye worm) phosphatidylinositol 3 0.005 0.0107 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0067 0.0163
Schistosoma mansoni lipoxygenase 0.0247 0.0723 0.1248
Trypanosoma brucei pyruvate kinase 1 0.0045 0.0089 0.0343
Schistosoma mansoni methyl-cpg binding protein mbd 0.0062 0.0142 0.0245
Brugia malayi Thioredoxin reductase 0.0177 0.0502 0.0548
Trypanosoma cruzi serine/threonine protein kinase, putative 0.004 0.0074 0.0286
Trichomonas vaginalis sensor histidine kinase, putative 0.0038 0.0069 0.0168
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.022 0.0639 0.0698
Leishmania major heat shock protein, putative 0.0147 0.0408 0.1577
Schistosoma mansoni heat shock protein 0.0242 0.0706 0.1218
Echinococcus multilocularis JmjC domain containing protein 4 0.0046 0.0093 0.0101
Echinococcus multilocularis axis inhibition protein axin 0.0077 0.019 0.0207
Schistosoma mansoni hypothetical protein 0.0083 0.0209 0.0361
Schistosoma mansoni DNA topoisomerase II 0.0038 0.0069 0.0118
Onchocerca volvulus 0.0064 0.0148 0.0362
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0023 0.002 0.009
Entamoeba histolytica DNA topoisomerase II, putative 0.0038 0.0069 0.0265
Trichomonas vaginalis AGC family protein kinase 0.004 0.0074 0.0181
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Mycobacterium ulcerans DNA polymerase IV 0.0073 0.0178 0.0545
Echinococcus multilocularis cyclin B3 1 0.0085 0.0215 0.0235
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0015 0.0036
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0021 0.0015 0.0036
Schistosoma mansoni nuclear receptor 0.0104 0.0275 0.0474
Trichomonas vaginalis importin beta-1, putative 0.0034 0.0056 0.0136
Schistosoma mansoni alpha-glucosidase 0.0118 0.0317 0.0548
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0044 0.017
Schistosoma mansoni pyruvate dehydrogenase 0.0038 0.0069 0.0118
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0403 0.1209 0.349
Schistosoma mansoni rab6-interacting 0.0051 0.0108 0.0186
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0061 0.0141 0.0628
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0403 0.1209 0.1209
Loa Loa (eye worm) acetyltransferase 0.0171 0.0485 0.0547
Schistosoma mansoni tar DNA-binding protein 0.0401 0.1202 0.2075
Giardia lamblia Hypothetical protein 0.0085 0.0215 0.0659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0067 0.0163
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0042 0.008 0.0308
Loa Loa (eye worm) hypothetical protein 0.0158 0.0443 0.05
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0217 0.0627 0.1924
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0111 0.0297 0.0513
Brugia malayi Regulator of G protein signaling domain containing protein 0.0077 0.019 0.0207
Giardia lamblia Hypothetical protein 0.0021 0.0013 0.0041
Onchocerca volvulus Pyruvate kinase homolog 0.0045 0.0089 0.0217
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Brugia malayi steroid hormone receptor 0.022 0.0639 0.0698
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.002 0.0011 0.0012
Echinococcus multilocularis inositol monophosphatase 1 0.0033 0.0051 0.0056
Schistosoma mansoni regulator of G protein signaling 0.0077 0.019 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0238 0.0581
Schistosoma mansoni cyclin k 0.0021 0.0013 0.0023
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0041 0.0079 0.0086
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0204 0.0586 0.064
Echinococcus multilocularis regulator of G protein signaling 7 0.0077 0.019 0.0207
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0038 0.0069 0.0265
Echinococcus granulosus ribosomal protein L19 0.0021 0.0015 0.0016
Schistosoma mansoni hypothetical protein 0.0035 0.0059 0.0102
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0217 0.0627 0.1924
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0064 0.0148 0.0148
Giardia lamblia hypothetical protein 0.0092 0.0238 0.0729
Toxoplasma gondii isocitrate dehydrogenase 0.011 0.0293 0.1307
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.022 0.0639 0.0721
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0107 0.0412
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0021 0.0015 0.0056
Echinococcus multilocularis endoplasmin 0.0219 0.0635 0.0694
Entamoeba histolytica hypothetical protein 0.0077 0.019 0.0733
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0148 0.0455
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0074 0.0128
Echinococcus multilocularis Cyclin L1 0.0021 0.0013 0.0015
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0177 0.0502 0.0502
Brugia malayi Heterochromatin protein 1 0.0078 0.0194 0.0212
Toxoplasma gondii isocitrate dehydrogenase 0.011 0.0293 0.1307
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.005 0.0107 0.0414
Trypanosoma brucei heat shock protein 90, putative 0.0242 0.0706 0.2726
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0069 0.0307
Brugia malayi Pre-SET motif family protein 0.1164 0.359 0.3921
Plasmodium vivax acetyl-CoA synthetase, putative 0.0064 0.0148 0.0662
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0192 0.047
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0148 0.0455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0084
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0092 0.0238 0.0919
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0147 0.0408 0.0446
Echinococcus granulosus inositol monophosphatase 1 0.0033 0.0051 0.0056
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0038 0.0069 0.0168
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0092 0.0238 0.1062
Schistosoma mansoni Smad4 0.0024 0.0025 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0067 0.0163
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0025 0.0044
Onchocerca volvulus Bile acid receptor homolog 0.022 0.0639 0.1561
Loa Loa (eye worm) glutaminase 0.062 0.1889 0.2131
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0015 0.0036
Schistosoma mansoni survival motor neuron protein 0.0083 0.0209 0.0361
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0073 0.0177 0.0685
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Onchocerca volvulus 0.022 0.0639 0.1561
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Toxoplasma gondii ribosomal protein RPL19 0.0021 0.0015 0.0065
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0331 0.0986 0.2409
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0064 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0053
Plasmodium falciparum phd finger protein, putative 0.0142 0.0394 0.176
Schistosoma mansoni hypothetical protein 0.0448 0.135 0.233
Loa Loa (eye worm) hypothetical protein 0.0356 0.1064 0.12
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.0033 0.0054 0.0059
Toxoplasma gondii heat shock protein HSP90 0.0242 0.0706 0.3153
Mycobacterium ulcerans recombinase A 0.0136 0.0373 0.1145
Giardia lamblia DNA damage repair protein 0.0023 0.002 0.0062
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0192 0.047
Schistosoma mansoni bromodomain containing protein 0.0232 0.0676 0.1167
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0074 0.0181
Echinococcus multilocularis expressed protein 0.1498 0.4633 0.5061
Plasmodium falciparum acyl-CoA synthetase 0.0162 0.0456 0.2036
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0046 0.0093 0.0414
Echinococcus multilocularis regulator of G protein signaling 3 0.0077 0.019 0.0207
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0021 0.0013 0.0051
Loa Loa (eye worm) RNA binding protein 0.0401 0.1202 0.1356
Giardia lamblia Cyclin B-like protein 0.0021 0.0013 0.0041
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0092 0.0238 0.1062
Loa Loa (eye worm) hypothetical protein 0.022 0.0639 0.0721
Loa Loa (eye worm) hypothetical protein 0.0038 0.0069 0.0077
Loa Loa (eye worm) PDE1B protein 0.0092 0.0238 0.0268
Entamoeba histolytica cyclin C, putative 0.0021 0.0013 0.0051
Trypanosoma cruzi heat shock protein 90, putative 0.0204 0.0586 0.2265

Activities

Activity type Activity value Assay description Source Reference
APTT (functional) = 44.2 s Compound was tested for the antithrombic effect in rat arterial thrombosis model and expressed as activated partial thromboplastin time(PTT) ChEMBL. 9873701
APTT (functional) = 44.2 s Compound was tested for the antithrombic effect in rat arterial thrombosis model and expressed as activated partial thromboplastin time(PTT) ChEMBL. 9873701
Ki (binding) = 3 nM Binding affinity of the compound against thrombin ChEMBL. 9873701
Ki (binding) = 3 nM Binding affinity of the compound against thrombin ChEMBL. 9873701
MOT (functional) = 47.7 min Compound was tested for the antithrombic effect in rat arterial thrombosis model and expressed as mean occlusion time(MOT) ChEMBL. 9873701
MOT (functional) = 47.7 min Compound was tested for the antithrombic effect in rat arterial thrombosis model and expressed as mean occlusion time(MOT) ChEMBL. 9873701
TT (functional) = 556.9 s Compound was tested for the antithrombic effect in rat arterial thrombosis model and expressed as thrombin time(TT) ChEMBL. 9873701
TT (functional) = 556.9 s Compound was tested for the antithrombic effect in rat arterial thrombosis model and expressed as thrombin time(TT) ChEMBL. 9873701

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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