Detailed information for compound 179072

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 259.302 | Formula: C11H21N3O4
  • H donors: 3 H acceptors: 4 LogP: 0.03 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=CN(C[C@H](C(=O)NC(=O)[C@@H](N)C)CC(C)C)O
  • InChi: 1S/C11H21N3O4/c1-7(2)4-9(5-14(18)6-15)11(17)13-10(16)8(3)12/h6-9,18H,4-5,12H2,1-3H3,(H,13,16,17)/t8-,9+/m0/s1
  • InChiKey: UZQQSSXSYSWTCT-DTWKUNHWSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bacillus thermoproteolyticus Thermolysin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0017 0.0059 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Mycobacterium ulcerans NAD synthetase 0.0016 0.005 0.0081
Echinococcus multilocularis smad 0.0017 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0041 0.0359 0.0552
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0112 0.018
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.0018 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Brugia malayi prolyl oligopeptidase family protein 0.0173 0.2016 0.3248
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0028 0.0045
Brugia malayi Adenosine kinase-like 0.0174 0.2026 0.3265
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0046 0.0074
Onchocerca volvulus 0.0154 0.1777 0.3239
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0338 0.0538
Loa Loa (eye worm) hypothetical protein 0.003 0.0228 0.0367
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0078 0.0826 0.0822
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0141 0.1609 0.1878
Trypanosoma cruzi nucleobase transporter, putative 0.0014 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Schistosoma mansoni neuropeptide F-like receptor 0.0078 0.0826 0.0954
Echinococcus granulosus sex peptide receptor 0.0078 0.0826 0.0969
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0136 0.1545 0.6449
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0107 0.1189 0.1911
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0232 0.0228
Echinococcus granulosus dro:myosuppressin receptor 0.0078 0.0826 0.0969
Brugia malayi MH2 domain containing protein 0.0017 0.0059 0.0095
Brugia malayi neuropeptide F receptor 0.0078 0.0826 0.1332
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0078 0.0826 0.0954
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0029 0.0047
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0338 0.0538
Loa Loa (eye worm) hypothetical protein 0.0031 0.0232 0.0374
Echinococcus granulosus neuropeptide receptor 0.0078 0.0826 0.0969
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0028 0.0045
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0047 0.0433 0.0553
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0046 0.0046
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0107 0.1189 0.1397
Trypanosoma brucei adenosine kinase, putative 0.0174 0.2026 0.3265
Echinococcus granulosus hypothetical protein 0.0078 0.0826 0.0969
Brugia malayi MH2 domain containing protein 0.0249 0.2971 0.4789
Entamoeba histolytica adenosine deaminase, putative 0.0201 0.2368 0.3798
Echinococcus multilocularis expressed protein 0.0373 0.452 0.4518
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0787 0.1026
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma cruzi GMP synthase [glutamine-hydrolysing] 0.0044 0.0394 0.0635
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0488 0.076
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0086 0.0139
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0014 0.0019 0.0017
Echinococcus multilocularis neuropeptide s receptor 0.0078 0.0826 0.0822
Echinococcus multilocularis prolyl endopeptidase 0.0014 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.0075 0.0787 0.1268
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0059 0.0095
Schistosoma mansoni hypothetical protein 0.0033 0.0265 0.0292
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0086 0.008
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0488 0.0484
Brugia malayi hypoxia-induced factor 1 0.015 0.1731 0.279
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.005 0.0081
Toxoplasma gondii nucleoside transporter protein 0.0014 0.0023 0.0008
Echinococcus granulosus solute carrier family 5 0.0038 0.0326 0.0379
Echinococcus multilocularis serotonin receptor 0.0078 0.0826 0.0822
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Echinococcus granulosus g protein coupled receptor 0.0078 0.0826 0.0969
Echinococcus multilocularis musashi 0.0027 0.0184 0.0179
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0232 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0107 0.1189 0.1911
Schistosoma mansoni nuclear receptor 0.0015 0.0028 0.0012
Loa Loa (eye worm) hypothetical protein 0.0081 0.0865 0.1394
Loa Loa (eye worm) phosphatidylinositol 3 0.0107 0.1189 0.1917
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0066 0.0676 0.1064
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0228 0.0339
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0172 0.0249
Schistosoma mansoni alpha-1 adrenergic receptor 0.0078 0.0826 0.0954
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0096 0.0092
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0232 0.0416
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0038 0.0326 0.0322
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0338 0.0538
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0004 0.0007
Brugia malayi MAP kinase sur-1 0.0051 0.0488 0.0786
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0061 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0066 0.0676 0.109
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0232 0.0253
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0086 0.008
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0019 0.0001
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.006 0.0598 0.0964
Echinococcus multilocularis sodium:nucleoside cotransporter 2 0.0224 0.2652 0.2649
Schistosoma mansoni amine GPCR 0.0078 0.0826 0.0954
Onchocerca volvulus 0.0078 0.0826 0.1502
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0078 0.0826 0.0969
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0058 0.0575 0.0927
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0014 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Echinococcus granulosus sodium:glucose cotransporter 0.0038 0.0326 0.0379
Echinococcus granulosus tm gpcr rhodopsin 0.0078 0.0826 0.0969
Brugia malayi G protein-coupled receptor 0.0078 0.0826 0.1332
Loa Loa (eye worm) hypothetical protein 0.0081 0.0865 0.1394
Schistosoma mansoni inositol transporter 0.0038 0.0326 0.0364
Entamoeba histolytica protein kinase rad3, putative 0.0066 0.0676 0.1064
Loa Loa (eye worm) TYRA-2 protein 0.0078 0.0826 0.1332
Loa Loa (eye worm) G-protein coupled receptor 0.0078 0.0826 0.1332
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0078 0.0826 0.1332
Brugia malayi beta-lactamase family protein 0.0075 0.0787 0.1268
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0026 0.004
Mycobacterium tuberculosis Conserved protein 0.0075 0.0787 0.1026
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0232 0.0253
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.006 0.0598 0.0594
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0078 0.0826 0.0822
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0136 0.1545 0.2468
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0107 0.1189 0.1893
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0066 0.0676 0.0792
Echinococcus granulosus sodium:myo inositol cotransporter 0.0038 0.0326 0.0379
Brugia malayi Serotonin receptor 0.0078 0.0826 0.1332
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0039 0.034 0.052
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0046 0.0042
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0507 0.6205 1
Echinococcus multilocularis sex peptide receptor 0.0078 0.0826 0.0822
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0787 0.1262
Onchocerca volvulus 0.0078 0.0826 0.1502
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0014 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Brugia malayi beta-lactamase family protein 0.0075 0.0787 0.1268
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0136 0.1545 0.1816
Leishmania major phosphatidylinositol 3-kinase, putative 0.0066 0.0676 0.109
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0206 0.0238
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0359 0.0572
Echinococcus multilocularis microtubule associated protein 2 0.0689 0.8487 0.8486
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0042 0.0372 0.06
Brugia malayi PAS domain containing protein 0.0049 0.0455 0.0733
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0058 0.0575 0.0927
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus granulosus serotonin receptor 0.0078 0.0826 0.0969
Trypanosoma brucei glucosidase, putative 0.0039 0.0338 0.0544
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0081 0.0865 0.1014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0139
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0086 0.0082
Trypanosoma brucei nucleoside transporter 1, putative 0.0014 0.0023 0.0037
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0184 0.0296
Echinococcus granulosus Smad4 0.0017 0.0059 0.0064
Onchocerca volvulus 0.0048 0.045 0.0814
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0028 0.0195 0.0314
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0201 0.2368 0.3798
Schistosoma mansoni opsin-like receptor 0.0078 0.0826 0.0954
Onchocerca volvulus 0.0038 0.0326 0.0588
Schistosoma mansoni survival motor neuron protein 0.0048 0.045 0.051
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0019 0.003
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0066 0.0676 0.1064
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0066 0.0676 0.109
Giardia lamblia Rrm3p helicase 0.0028 0.0195 0.1158
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0826 0.0969
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0165 0.0238
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0173 0.2016 0.3675
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0136 0.1545 0.1803
Mycobacterium tuberculosis Probable GMP synthase [glutamine-hydrolyzing] GuaA (glutamine amidotransferase) (GMP synthetase) 0.0022 0.0123 0.014
Mycobacterium tuberculosis Conserved protein 0.0075 0.0787 0.1026
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0116 0.1305 0.1534
Schistosoma mansoni hypothetical protein 0.0014 0.0026 0.001
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0066 0.0676 0.0777
Loa Loa (eye worm) neuropeptide F receptor 0.0078 0.0826 0.1332
Schistosoma mansoni zinc finger protein 0.0015 0.0028 0.0012
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Mycobacterium leprae Probable lipase LipE 0.0075 0.0787 0.1262
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0787 0.0922
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0141 0.1609 0.1892
Echinococcus granulosus cpg binding protein 0.003 0.0226 0.0261
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Echinococcus multilocularis G-protein coupled receptor, putative 0.0078 0.0826 0.0822
Loa Loa (eye worm) hypothetical protein 0.0347 0.4199 0.6767
Onchocerca volvulus 0.0237 0.2821 0.5147
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0014 0.0018 0.0029
Brugia malayi RE15519p 0.0078 0.0826 0.1332
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Brugia malayi prolyl oligopeptidase family protein 0.0058 0.0575 0.0927
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0136 0.1545 0.249
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0058 0.0575 0.0927
Schistosoma mansoni alpha-glucosidase 0.0152 0.1754 0.205
Toxoplasma gondii FATC domain-containing protein 0.0066 0.0676 0.1064
Brugia malayi Glycosyl hydrolases family 31 protein 0.0177 0.2062 0.3324
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0136 0.1545 0.249
Schistosoma mansoni biogenic amine receptor 0.0078 0.0826 0.0954
Schistosoma mansoni hypothetical protein 0.0039 0.034 0.038
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0028 0.0195 0.0314
Leishmania major phosphatidylinositol 3-kinase, putative 0.0107 0.1189 0.1917
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0297 0.0478
Echinococcus multilocularis fmrfamide receptor 0.0078 0.0826 0.0822
Loa Loa (eye worm) hypothetical protein 0.0089 0.0959 0.1546
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0172 0.0249
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.005 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0826 0.0954
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0107 0.1189 0.1911
Trypanosoma brucei purine nucleoside transporter 0.0014 0.0023 0.0037
Leishmania major adenosine kinase-like protein 0.002 0.0094 0.0152
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0141 0.1609 0.2588
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0232 0.0253
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0826 0.0822
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0232 0.0253
Onchocerca volvulus 0.0449 0.5478 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0066 0.0676 0.109
Echinococcus multilocularis somatostatin receptor 0.0078 0.0826 0.0822
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0028 0.0012
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0107 0.1189 0.1917
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0297 0.0478
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0017 0.0059 0.0055
Brugia malayi hypothetical protein 0.0044 0.0403 0.065
Trichomonas vaginalis adenosine deaminase, putative 0.0201 0.2368 0.3812
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0232 0.0374
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0016 0.005 0.0052
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0086 0.0139
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0089 0.0959 0.1126
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0046 0.0074
Echinococcus multilocularis orexin receptor type 2 0.0078 0.0826 0.0822
Schistosoma mansoni alpha-glucosidase 0.0152 0.1754 0.205
Brugia malayi Smad1 0.0017 0.0059 0.0095
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0028 0.0012
Leishmania major S-adenosylhomocysteine hydrolase 0.0507 0.6205 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0078 0.0826 0.0969
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0066 0.0676 0.109
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0232 0.0228
Loa Loa (eye worm) hypothetical protein 0.0075 0.0787 0.1268
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0141 0.1609 0.2593
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0107 0.1189 0.1917
Brugia malayi Dopamine receptor 0.0078 0.0826 0.1332
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0086 0.0132
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0116 0.1305 0.2081
Brugia malayi sulfakinin receptor protein 0.0078 0.0826 0.1332
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0046 0.0046
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0038 0.0326 0.0322
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0432 0.0488
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0066 0.0676 0.109
Echinococcus granulosus 7TM GPCR rhodopsin 0.0078 0.0826 0.0969
Onchocerca volvulus 0.0078 0.0826 0.1502
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0066 0.0676 0.109
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0449 0.5478 0.6452
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0078 0.0826 0.1502
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0078 0.0826 0.0969
Onchocerca volvulus 0.0075 0.0787 0.1429
Loa Loa (eye worm) hypothetical protein 0.0075 0.0787 0.1268
Echinococcus multilocularis AMP deaminase 2 0.0335 0.4047 0.4044
Schistosoma mansoni growth hormone secretagogue receptor 0.0078 0.0826 0.0954
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0089 0.0958 0.6157
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0086 0.008
Trypanosoma cruzi AMP deaminase, putative 0.0335 0.4047 0.6522
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0009 0.0005
Loa Loa (eye worm) G-protein coupled receptor 0.0078 0.0826 0.1332
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0014 0.0018 0.000000030812
Trypanosoma brucei ribokinase, putative 0.002 0.0094 0.0152
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0023 0.003
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0086 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0676 0.1084
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0112 0.0614
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0335 0.4047 0.6522
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0066 0.0676 0.0792
Brugia malayi Pre-SET motif family protein 0.0208 0.246 0.3964
Schistosoma mansoni high-affinity choline transporter 0.0347 0.4199 0.4936
Schistosoma mansoni AMP deaminase 0.0335 0.4047 0.4757
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0107 0.1189 0.1911
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0338 0.0517
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus multilocularis lamin dm0 0.0027 0.0184 0.0179
Brugia malayi hypothetical protein 0.0016 0.0052 0.0084
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0232 0.0228
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.1037 0.1203
Plasmodium vivax GMP synthetase, putative 0.006 0.0598 0.0938
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0826 0.0954
Loa Loa (eye worm) hypothetical protein 0.0107 0.1189 0.1917
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0078 0.0826 0.0822
Brugia malayi Nucleoside transporter family protein 0.0081 0.0865 0.1394
Trypanosoma cruzi AMP deaminase, putative 0.0335 0.4047 0.6522
Brugia malayi conserved hypotetical protein 0.0015 0.0028 0.0045
Brugia malayi putative neuropeptide receptor NPR1 0.0078 0.0826 0.1332
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0232 0.0374
Onchocerca volvulus 0.0078 0.0826 0.1502
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0488 0.078
Schistosoma mansoni biogenic amine (5HT) receptor 0.0078 0.0826 0.0954
Schistosoma mansoni smad1 5 8 and 0.0017 0.0059 0.0048
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0507 0.6205 1
Loa Loa (eye worm) phosphatidylinositol kinase 0.0449 0.5478 0.8828
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0078 0.0826 0.1332
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0041 0.0359 0.0579
Echinococcus multilocularis cpg binding protein 0.003 0.0226 0.0222
Plasmodium vivax adenosine deaminase, putative 0.0201 0.2368 0.3798
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0107 0.1189 0.1911
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0228 0.0248
Toxoplasma gondii kinase, pfkB family protein 0.0174 0.2026 0.3245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.2062 0.2059
Onchocerca volvulus Huntingtin homolog 0.0122 0.138 0.2514
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0826 0.0969
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0116 0.1305 0.2104
Trypanosoma cruzi nucleoside transporter 1, putative 0.0014 0.0023 0.0037
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0232 0.0228
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0141 0.1609 0.2593
Brugia malayi hypothetical protein 0.0236 0.2807 0.4524
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0028 0.0045
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0107 0.1189 0.1911
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0173 0.2016 0.2359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0826 0.0954
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0014 0.0018 0.0022
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0027 0.0043
Entamoeba histolytica nucleoside transporter, putative 0.0014 0.0023 0.0008
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0107 0.1189 0.1383
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0046 0.0033
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.005 0.0046
Trypanosoma cruzi target of rapamycin kinase 3 0.0066 0.0676 0.109
Entamoeba histolytica hypothetical protein 0.0066 0.0676 0.1064
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0038 0.0326 0.0498
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0297 0.0293
Schistosoma mansoni microtubule-associated protein tau 0.0689 0.8487 1
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.0018 0.0029
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0232 0.0253
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0086 0.008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0232 0.0374
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0116 0.1305 0.2104
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Toxoplasma gondii ABC1 family protein 0.0075 0.0787 0.1242
Toxoplasma gondii 1-phosphatidylinositol 4-kinase 0.005 0.0475 0.0739
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0232 0.0269
Entamoeba histolytica nucleoside transporter, putative 0.0014 0.0023 0.0008
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0116 0.1305 0.2104
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0232 0.0269
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0017 0.0059 0.0055
Trypanosoma brucei prolyl oligopeptidase, putative 0.0014 0.0018 0.0029
Entamoeba histolytica ribokinase, putative 0.002 0.0094 0.0123
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0449 0.5478 0.6452
Giardia lamblia Hypothetical protein 0.0066 0.0676 0.4311
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0787 0.1262
Loa Loa (eye worm) neuropeptide F receptor 0.0078 0.0826 0.1332
Mycobacterium tuberculosis Ribokinase RbsK 0.002 0.0094 0.0102
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.0169 0.1968 0.2302
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0066 0.0676 0.109
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0086 0.0096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0826 0.0954
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0139 0.0217
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0004
Schistosoma mansoni cpg binding protein 0.003 0.0226 0.0246
Trypanosoma brucei unspecified product 0.0014 0.0023 0.0037
Brugia malayi Cyclic-nucleotide gated cation channel 0.0014 0.0019 0.003
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0029 0.004
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0136 0.1545 0.249
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0172 0.0277
Toxoplasma gondii adenosylhomocysteinase, putative 0.0507 0.6205 1
Toxoplasma gondii kinase, pfkB family protein 0.002 0.0094 0.0123
Loa Loa (eye worm) hypothetical protein 0.0062 0.0627 0.1011
Loa Loa (eye worm) hypothetical protein 0.0317 0.3818 0.6154
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0066 0.0676 0.0672
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0017 0.0059 0.0049
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0184 0.0296
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.005 0.0054
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.0201 0.2368 0.3135
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0488 0.0786
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0096 0.0154
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0232 0.0228
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0028 0.0024
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0232 0.0228
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0014 0.0023 0.0037
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0232 0.0253
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0488 0.057
Brugia malayi Ribokinase 0.002 0.0094 0.0152
Entamoeba histolytica hypothetical protein 0.0019 0.0086 0.011
Brugia malayi hypothetical protein 0.0016 0.005 0.0081
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0078 0.0826 0.0954
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0787 0.1242
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0066 0.0676 0.1064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0029 0.004
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0338 0.0393
Echinococcus granulosus snurportin 1 0.0307 0.37 0.4357
Echinococcus granulosus g protein coupled receptor 0.0078 0.0826 0.0969
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0232 0.0374
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0136 0.1545 0.2485
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0826 0.0822
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.0826 0.0954
Schistosoma mansoni biogenic amine receptor 0.0078 0.0826 0.0954
Schistosoma mansoni amine GPCR 0.0078 0.0826 0.0954
Echinococcus granulosus equilibrative nucleoside transporter 0.0081 0.0865 0.1014
Schistosoma mansoni amine GPCR 0.0078 0.0826 0.0954
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0004 0.0007
Schistosoma mansoni alpha glucosidase 0.0039 0.0338 0.0378
Brugia malayi Death domain containing protein 0.0014 0.0026 0.0042
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0066 0.0676 0.0792
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0112 0.0107
Loa Loa (eye worm) hypothetical protein 0.0031 0.0232 0.0374
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Echinococcus multilocularis neuropeptide Y receptor 0.0078 0.0826 0.0822
Schistosoma mansoni histamine h1 receptor 0.0078 0.0826 0.0954
Leishmania major adenine aminohydrolase 0.0201 0.2368 0.3816
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0019 0.0014
Echinococcus multilocularis neuropeptide receptor 0.0078 0.0826 0.0822
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0107 0.1189 0.1893
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0029
Onchocerca volvulus 0.0031 0.0232 0.0416
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0136 0.1545 0.1816
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0019 0.003
Trypanosoma brucei adenosine transporter, putative 0.0014 0.0023 0.0037
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0078 0.0826 0.0822
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0172 0.0277
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0046 0.0074
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0232 0.0269
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0042 0.0372 0.06
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0019 0.0001
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0195 0.0286
Schistosoma mansoni biogenic amine receptor 0.0078 0.0826 0.0954
Schistosoma mansoni adenosine deaminase-related 0.0201 0.2368 0.2775
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0826 0.0969
Plasmodium vivax adenosine/AMP deaminase, putative 0.0335 0.4047 0.6512
Echinococcus granulosus fmrfamide receptor 0.0078 0.0826 0.0969
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0136 0.1545 0.2468
Brugia malayi GH02984p 0.0347 0.4199 0.6767
Echinococcus multilocularis adenosine kinase 0.0174 0.2026 0.2022
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0023 0.0037
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0136 0.1545 0.2468
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.034 0.0547
Trypanosoma brucei protein kinase, putative 0.0051 0.0488 0.0786
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0086 0.008
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0019 0.0014
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0014 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0228 0.0248
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0141 0.1609 0.2593
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0023 0.003
Trypanosoma brucei NAD+ synthase, putative 0.0016 0.005 0.0081
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0042 0.0372 0.06
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0232 0.0253
Trypanosoma brucei adenosine transporter 2 0.0014 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Entamoeba histolytica DNA repair and recombination protein, putative 0.0028 0.0195 0.0286
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0449 0.5478 0.6447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0232 0.0374
Toxoplasma gondii nucleoside transporter protein 0.0014 0.0023 0.0008
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0023 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0107 0.1189 0.1917
Echinococcus granulosus g-protein coupled receptor 0.0078 0.0826 0.0969
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0029 0.0047
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0028 0.0195 0.0314
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.2971 0.4789
Trypanosoma cruzi nucleoside transporter 1, putative 0.0014 0.0023 0.0037
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0139 0.0217
Loa Loa (eye worm) hypothetical protein 0.0039 0.034 0.0547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Toxoplasma gondii AMP deaminase 0.0335 0.4047 0.6512
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0488 0.3078
Loa Loa (eye worm) phosphatidylinositol 3 0.0449 0.5478 0.8828
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0488 0.0786
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0059 0.0055
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0078 0.0826 0.1332
Echinococcus granulosus neuropeptides capa receptor 0.0078 0.0826 0.0969
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0389 0.0385
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0066 0.0676 0.109
Toxoplasma gondii nucleoside transporter protein 0.0014 0.0023 0.0008
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0019 0.0001
Mycobacterium ulcerans lipase LipD 0.0075 0.0787 0.1268
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0014 0.0019 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus multilocularis solute carrier family 28 0.0343 0.4149 0.4147
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0018 0.0029
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0042 0.0372 0.06
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0066 0.0676 0.109
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0107 0.1189 0.1893
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0787 0.1026
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0086 0.0096
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0232 0.0269
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0028 0.0045
Loa Loa (eye worm) hypothetical protein 0.0174 0.2026 0.3265
Entamoeba histolytica hypothetical protein 0.0107 0.1189 0.1893
Trypanosoma cruzi NAD+ synthase, putative 0.0016 0.005 0.0081
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0207 0.0203
Brugia malayi G-protein coupled receptor 0.0078 0.0826 0.1332
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0338 0.0544
Trypanosoma cruzi nucleobase transporter, putative 0.0014 0.0023 0.0037
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.002 0.0094 0.009
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0078 0.0826 0.1332
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0152
Schistosoma mansoni adenosylhomocysteinase 0.0507 0.6205 0.7305
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0058 0.0575 0.0927
Brugia malayi hypothetical protein 0.0122 0.138 0.2224
Echinococcus granulosus lysosomal alpha glucosidase 0.0177 0.2062 0.2426
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0232 0.0374
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0029 0.0047
Echinococcus granulosus neuropeptide receptor A26 0.0078 0.0826 0.0969
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0479 0.5856 0.7789
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0107 0.1189 0.1893
Schistosoma mansoni hypothetical protein 0.0052 0.0494 0.0562
Echinococcus granulosus neuropeptide receptor 0.0078 0.0826 0.0969
Echinococcus multilocularis G protein coupled receptor 139 0.0078 0.0826 0.0822
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0019 0.0014
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0141 0.1609 0.2593
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0488 0.0786
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0107 0.1189 0.1186
Leishmania major oligopeptidase b 0.0014 0.0018 0.0029
Onchocerca volvulus 0.0078 0.0826 0.1502
Onchocerca volvulus 0.0449 0.5478 1
Brugia malayi nuclear receptor RXR 0.0015 0.0028 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0081
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma brucei adenosine transporter, putative 0.0014 0.0023 0.0037
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0066 0.0676 0.109
Brugia malayi adenosine monophosphate deaminase 0.0335 0.4047 0.6522
Leishmania major putative PfkB family sugar kinase 0.002 0.0094 0.0152
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0107 0.1189 0.1917
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0046 0.0074
Brugia malayi hypothetical protein 0.0081 0.0865 0.1394
Schistosoma mansoni adenosine kinase 0.0174 0.2026 0.2371
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0014 0.0018 0.0029
Echinococcus multilocularis fmrfamide receptor 0.0078 0.0826 0.0822
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0028 0.0044
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0066 0.0676 0.1064
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0086 0.0132
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0086 0.0082
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0787 0.1268
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0014 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0062 0.0627 0.1011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0623 0.0714
Echinococcus multilocularis dro:myosuppressin receptor 0.0078 0.0826 0.0822
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0096 0.0092
Brugia malayi hypothetical protein 0.0016 0.005 0.0081
Leishmania major importin beta-1 subunit, putative 0.0023 0.0139 0.0224
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0066 0.0676 0.109
Schistosoma mansoni adenosylhomocysteinase 0.0314 0.3781 0.4443
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0089 0.0958 0.1544
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0228 0.0263
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0449 0.5478 0.5476
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0029 0.004
Echinococcus granulosus 7tm_1 domain containing protein 0.0078 0.0826 0.0969
Trypanosoma cruzi nucleoside transporter 1, putative 0.0014 0.0023 0.0037
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0507 0.6205 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0059 0.0064
Echinococcus granulosus somatostatin receptor 0.0078 0.0826 0.0969
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0078 0.0826 0.0822
Leishmania major AMP deaminase, putative 0.0335 0.4047 0.6522
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.2807 0.3304
Trypanosoma cruzi AMP deaminase 2, putative 0.0139 0.1587 0.2557
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0086 0.0082
Echinococcus granulosus solute carrier family 28 0.0343 0.4149 0.4886
Mycobacterium leprae Probable GMP synthase [glutamine-hydrolyzing] GuaA (Glutamine amidotransferase) (GMP synthetase) 0.0022 0.0123 0.0191
Schistosoma mansoni adenosylhomocysteinase 0.0314 0.3781 0.4443
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0028 0.0045
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0136 0.1545 0.249
Brugia malayi MH1 domain containing protein 0.0017 0.0059 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0232 0.0374
Brugia malayi Sodium:solute symporter family protein 0.0038 0.0326 0.0525
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0046 0.0038
Loa Loa (eye worm) hypoxia-induced factor 1 0.015 0.1731 0.279
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0335 0.4047 0.6522
Echinococcus multilocularis allatostatin A receptor 0.0078 0.0826 0.0822
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0033 0.0265 0.0428
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0029 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0029 0.004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0046 0.0042
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0136 0.1545 0.1541
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0028 0.0028
Echinococcus granulosus adenosine kinase 0.0174 0.2026 0.2383
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0139 0.0217
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.1037 0.1033
Loa Loa (eye worm) Smad1 0.0017 0.0059 0.0095
Brugia malayi intermediate filament protein 0.0027 0.0184 0.0296
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0029 0.0047
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0335 0.4047 0.6522
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0028 0.0024
Onchocerca volvulus 0.0078 0.0826 0.1502
Echinococcus multilocularis serotonin receptor 0.0078 0.0826 0.0822
Echinococcus multilocularis 0.0116 0.1305 0.1302
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0507 0.6205 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0078 0.0826 0.0822
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0107 0.1189 0.1397
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0028 0.0012
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0023 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0232 0.0374
Mycobacterium ulcerans GMP synthase 0.006 0.0598 0.0964
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0228 0.0248
Loa Loa (eye worm) hypothetical protein 0.0075 0.0787 0.1268
Leishmania major tagatose-6-phosphate kinase-like protein 0.002 0.0094 0.0152
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0066 0.0676 0.109
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0136 0.1545 0.249
Brugia malayi GnHR receptor homolog 0.0078 0.0826 0.1332
Onchocerca volvulus 0.0078 0.0826 0.1502
Onchocerca volvulus 0.0078 0.0826 0.1502
Brugia malayi Importin beta-1 subunit 0.0029 0.0207 0.0334
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0028 0.0195 0.0314
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0201 0.2368 0.3798
Echinococcus granulosus neuropeptide Y receptor 0.0078 0.0826 0.0969
Echinococcus granulosus lamin dm0 0.0027 0.0184 0.0211
Echinococcus granulosus alpha 1A adrenergic receptor 0.0078 0.0826 0.0969
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0232 0.0253
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0014 0.0019 0.0014
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0066 0.0676 0.109
Brugia malayi MH1 domain containing protein 0.0017 0.0059 0.0095
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0081 0.0865 0.1388
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0028 0.0024
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0136 0.1545 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0826 0.0969
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0232 0.0374
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0136 0.1545 1
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0017 0.0059 0.0065
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0541 0.0845
Schistosoma mansoni adenosylhomocysteinase 0.0314 0.3781 0.4443
Loa Loa (eye worm) DR-78 0.0015 0.0028 0.0045
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0141 0.1609 0.2588
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0207 0.0334
Leishmania major phosphatidylinositol kinase related protein, putative 0.0066 0.0676 0.109
Onchocerca volvulus 0.0078 0.0826 0.1502
Leishmania major hypothetical protein, conserved 0.0025 0.0165 0.0267
Schistosoma mansoni ribokinase 0.002 0.0094 0.009
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0136 0.1545 0.1541
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.1037 0.1203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Loa Loa (eye worm) hypothetical protein 0.0031 0.0232 0.0374
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0019 0.0001
Echinococcus granulosus importin subunit beta 1 0.0029 0.0207 0.0239
Onchocerca volvulus 0.0027 0.0184 0.0328
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0787 0.1262
Plasmodium falciparum AMP deaminase, putative 0.0335 0.4047 0.6512
Trypanosoma cruzi oligopeptidase b 0.0014 0.0018 0.0029
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0136 0.1545 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0165 0.0267
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0228 0.0248
Trichomonas vaginalis set domain proteins, putative 0.0237 0.282 0.4541
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0232 0.0228
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0136 0.1545 0.249
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0338 0.0538
Loa Loa (eye worm) hypothetical protein 0.0449 0.5478 0.8828
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0081 0.0865 0.1388
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0028 0.0195 0.0314
Loa Loa (eye worm) melatonin receptor type 1A 0.0078 0.0826 0.1332
Schistosoma mansoni flap endonuclease-1 0.0024 0.0141 0.0145
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0099
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0107 0.1189 0.1397
Loa Loa (eye worm) hypothetical protein 0.0031 0.0232 0.0374
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0165 0.0267
Loa Loa (eye worm) hypothetical protein 0.0029 0.0207 0.0334
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0826 0.0822
Toxoplasma gondii target of rapamycin (TOR), putative 0.0066 0.0676 0.1064
Leishmania major nucleoside transporter 1, putative 0.0014 0.0023 0.0037
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0107 0.1189 0.1917
Plasmodium falciparum adenosine deaminase 0.0201 0.2368 0.3798
Brugia malayi Pre-SET motif family protein 0.003 0.0228 0.0367
Schistosoma mansoni GMP synthetase 0.006 0.0598 0.0685
Onchocerca volvulus Huntingtin homolog 0.0122 0.138 0.2514
Trypanosoma brucei ribokinase, putative 0.002 0.0094 0.0152
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0826 0.0954
Brugia malayi nuclear hormone receptor 0.0015 0.0028 0.0045
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0389 0.0627
Schistosoma mansoni lamin 0.0027 0.0184 0.0196
Onchocerca volvulus 0.0027 0.0184 0.0328
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0232 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0086 0.0132
Brugia malayi nuclear receptor NHR-88 0.0031 0.0232 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0086 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Onchocerca volvulus Ribokinase homolog 0.002 0.0094 0.0165
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0136 0.1545 0.2468
Schistosoma mansoni adenoreceptor 0.0078 0.0826 0.0954
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0089 0.0958 0.1544
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0136 0.1545 0.249
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0023 0.0037
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0086 0.0096
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0046 0.0042
Loa Loa (eye worm) hypothetical protein 0.0031 0.0232 0.0374
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0096 0.0154
Brugia malayi larval opioid receptor 0.0078 0.0826 0.1332
Schistosoma mansoni importin beta-1 0.0029 0.0207 0.0223
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0165 0.0267
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Entamoeba histolytica NAD synthetase, putative 0.0016 0.005 0.0052
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0078 0.0826 0.0969
Schistosoma mansoni hypothetical protein 0.0169 0.1968 0.2302
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0078 0.0826 0.0954
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0028 0.0045
Brugia malayi nuclear receptor NHR-67 0.0015 0.0028 0.0045
Schistosoma mansoni ran 0.0021 0.0112 0.0111
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.034 0.052
Schistosoma mansoni hypothetical protein 0.0066 0.0676 0.0777
Trypanosoma cruzi nucleoside transporter-like, putative 0.0014 0.0023 0.0037
Trypanosoma brucei purine nucleoside transporter 0.0014 0.0023 0.0037
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0136 0.1545 0.249
Loa Loa (eye worm) hypothetical protein 0.0026 0.0177 0.0286
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.045 0.0725
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0042 0.0372 0.06
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0038 0.0326 0.0379
Schistosoma mansoni hypothetical protein 0.0307 0.37 0.4348
Brugia malayi tailless protein 0.0015 0.0028 0.0045
Loa Loa (eye worm) AMP deaminase 0.0335 0.4047 0.6522
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0787 0.1268
Schistosoma mansoni single-minded 0.0049 0.0455 0.0516
Echinococcus granulosus sodium:glucose cotransporter 2 0.0038 0.0326 0.0379
Echinococcus granulosus Ankyrin 0.0014 0.0028 0.0027
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0086 0.0096
Schistosoma mansoni neuropeptide receptor 0.0078 0.0826 0.0954
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0338 0.0538
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0028 0.0044
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0335 0.4047 0.6522
Schistosoma mansoni adenosylhomocysteinase 0.0314 0.3781 0.4443
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0028 0.0012
Echinococcus granulosus acylamino acid releasing enzyme 0.0014 0.0018 0.0016
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0028 0.0045
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0081 0.0865 0.0861
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0086 0.008
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0136 0.1545 0.2485
Echinococcus granulosus g protein coupled receptor 0.0078 0.0826 0.0969
Loa Loa (eye worm) hypothetical protein 0.0033 0.0265 0.0428
Trypanosoma cruzi NAD+ synthase, putative 0.0016 0.005 0.0081
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0232 0.0253
Loa Loa (eye worm) hypothetical protein 0.0075 0.0787 0.1268
Echinococcus granulosus lamin 0.0027 0.0184 0.0211
Brugia malayi Uncoordinated protein 44 0.0014 0.0026 0.0042
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0066 0.0676 0.1084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0026 0.0042
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0116 0.1305 0.152
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0023 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0022
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0078 0.0826 0.1332
Echinococcus granulosus ribokinase 0.002 0.0094 0.0106
Mycobacterium ulcerans fructokinase, PfkB 0.002 0.0094 0.0152
Loa Loa (eye worm) hypothetical protein 0.0139 0.1587 0.2557
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0038 0.0326 0.0322
Echinococcus multilocularis g protein coupled receptor 0.0078 0.0826 0.0822
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0136 0.1545 0.249
Echinococcus multilocularis serine protein kinase ATM 0.0066 0.0676 0.0672
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0017 0.0061 0.0099
Schistosoma mansoni amine GPCR 0.0078 0.0826 0.0954
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0078 0.0826 0.0954
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0078 0.0826 0.0822
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0173 0.2016 0.2371
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0014 0.0018 0.0029
Plasmodium falciparum flap endonuclease 1 0.0026 0.0172 0.0249
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0787 0.1268
Echinococcus multilocularis neuropeptide Y receptor 0.0078 0.0826 0.0822
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.0826 0.0954
Trypanosoma cruzi AMP deaminase, putative 0.0335 0.4047 0.6522
Entamoeba histolytica hypothetical protein 0.0066 0.0676 0.1064
Onchocerca volvulus 0.0078 0.0826 0.1502
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0028 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0096 0.0092
Echinococcus multilocularis Zinc finger, PHD finger 0.0107 0.1189 0.1186
Brugia malayi steroid hormone receptor 0.0031 0.0232 0.0374
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0004 0.0007
Brugia malayi Adenosylhomocysteinase 0.0507 0.6205 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Onchocerca volvulus 0.0075 0.0787 0.1429
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.034 0.0547
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0061 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0031 0.0232 0.0374
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0078 0.0826 0.1332
Echinococcus multilocularis adenosylhomocysteinase 0.0507 0.6205 0.6203
Loa Loa (eye worm) hypothetical protein 0.0122 0.138 0.2224
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0232 0.0374
Brugia malayi Melatonin receptor type 1A 0.0078 0.0826 0.1332
Echinococcus granulosus tachykinin peptides receptor 99D 0.0078 0.0826 0.0969
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0078 0.0826 0.1332
Trypanosoma cruzi adenosine kinase, putative 0.002 0.0094 0.0152
Echinococcus granulosus orexin receptor type 2 0.0078 0.0826 0.0969
Brugia malayi hypothetical protein 0.002 0.0094 0.0152
Leishmania major phosphatidylinositol kinase, putative 0.0066 0.0676 0.109
Onchocerca volvulus 0.0078 0.0826 0.1502
Loa Loa (eye worm) hypothetical protein 0.0014 0.0026 0.0042
Brugia malayi Tachykinin-like peptides receptor 99D 0.0078 0.0826 0.1332
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0787 0.1262
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0449 0.5478 0.5476
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0139
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0488 0.0786
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0081
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0787 0.1026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0027 0.0043
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0165 0.0238
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0066 0.0676 0.0672
Brugia malayi ecdysone receptor 0.0015 0.0028 0.0045
Echinococcus multilocularis ribokinase 0.002 0.0094 0.009
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0066 0.0676 0.0792
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0488 0.0786
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0136 0.1545 0.2468
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus granulosus neuropeptide s receptor 0.0078 0.0826 0.0969
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0112 0.018
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0107 0.1189 0.1893
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.034 0.0336
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0066 0.0676 0.109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0086 0.0139
Entamoeba histolytica adenosine deaminase, putative 0.0201 0.2368 0.3798
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0232 0.0228
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0488 0.057
Onchocerca volvulus 0.0078 0.0826 0.1502
Entamoeba histolytica hypothetical protein 0.0023 0.0139 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0195 0.0307
Echinococcus multilocularis high affinity choline transporter 1 0.0347 0.4199 0.4196
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.1037 0.1203
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0058 0.0575 0.0901
Schistosoma mansoni cpg binding protein 0.0029 0.0206 0.0222
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0089 0.0959 0.1546
Schistosoma mansoni hypothetical protein 0.0078 0.0826 0.0954
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0107 0.1189 0.1893
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0086 0.008
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0139 0.0224
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0078 0.0826 0.1332
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0066 0.0676 0.109
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0028 0.0024
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0026 0.0026
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0028 0.0195 0.0314
Trypanosoma brucei unspecified product 0.0014 0.0023 0.0037
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0081 0.0865 0.1388
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma cruzi GMP synthase, putative 0.002 0.0094 0.0152
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0014 0.0018 0.0029
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0016 0.005 0.0043
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0078 0.0826 0.0954
Trypanosoma brucei nucleoside transporter 1, putative 0.0014 0.0023 0.0037
Brugia malayi beta-lactamase 0.0075 0.0787 0.1268
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0787 0.1262
Entamoeba histolytica hypothetical protein 0.0019 0.0086 0.011
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0107 0.1189 0.1383
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0058 0.0575 0.0571
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0028 0.0012
Brugia malayi isocitrate dehydrogenase 0.0016 0.0046 0.0074
Loa Loa (eye worm) hypothetical protein 0.0031 0.0232 0.0374
Schistosoma mansoni opsin-like receptor 0.0078 0.0826 0.0954
Leishmania major hypothetical protein, conserved 0.0075 0.0787 0.1268
Brugia malayi PXA domain containing protein 0.0019 0.0086 0.0139
Brugia malayi Serotonin receptor 0.0078 0.0826 0.1332
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0089 0.0958 0.1544
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0107 0.1189 0.1911
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0787 0.1268
Schistosoma mansoni nuclear receptor 0.0015 0.0028 0.0012
Brugia malayi putative neuropeptide receptor 0.0078 0.0826 0.1332
Leishmania major protein kinase, putative 0.0013 0.0014 0.0022
Echinococcus granulosus flap endonuclease 1 0.0026 0.0172 0.0198
Loa Loa (eye worm) phosphatidylinositol 3 0.0066 0.0676 0.109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0086 0.0096
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0172 0.1009
Leishmania major GTP-binding protein, putative 0.0021 0.0112 0.018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0078 0.0826 0.0822
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0139
Loa Loa (eye worm) hypothetical protein 0.0075 0.0787 0.1268
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0066 0.0676 0.1064
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0096 0.0108
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0081 0.0865 0.1572
Echinococcus multilocularis Ankyrin 0.0014 0.0028 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0232 0.0374
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.0018 0.0029
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0141 0.1609 0.2593
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0136 0.1545 0.1803
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0046 0.0046
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0488 0.078
Brugia malayi nuclear receptor RXR 0.0016 0.005 0.0081
Schistosoma mansoni smad1 5 8 and 0.0017 0.0059 0.0048
Echinococcus granulosus neuropeptides capa receptor 0.0078 0.0826 0.0969
Schistosoma mansoni ran 0.0021 0.0112 0.0111
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0112 0.0127
Onchocerca volvulus Neuropeptide F receptor homolog 0.0078 0.0826 0.1502
Giardia lamblia Ribokinase 0.002 0.0094 0.05
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0086 0.008
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0014 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0449 0.5478 0.8828
Echinococcus granulosus high affinity choline transporter 1 0.0347 0.4199 0.4944
Loa Loa (eye worm) hypothetical protein 0.0236 0.2807 0.4524
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0228 0.0223
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0066 0.0676 0.109
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0047 0.0432 0.0696
Brugia malayi hypothetical protein 0.0025 0.0165 0.0267
Brugia malayi PXA domain containing protein 0.0019 0.0086 0.0139
Schistosoma mansoni amine GPCR 0.0078 0.0826 0.0954
Echinococcus granulosus Dipeptidyl peptidase 9 0.0058 0.0575 0.0673
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.1037 0.1033
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0023 0.003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Onchocerca volvulus 0.0075 0.0787 0.1429
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0023 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0826 0.0822
Treponema pallidum adenosine deaminase 0.0201 0.2368 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0046 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus granulosus G protein coupled receptor 139 0.0078 0.0826 0.0969
Loa Loa (eye worm) hypothetical protein 0.0033 0.0265 0.0428
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0089 0.0959 0.1546
Loa Loa (eye worm) hypothetical protein 0.0062 0.0627 0.1011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0826 0.0954
Onchocerca volvulus 0.0015 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.01 0.1096 0.1742
Giardia lamblia NH3-dependent NAD+ synthetase 0.0016 0.005 0.021
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0017 0.0059 0.0055
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0014 0.0019 0.0014
Echinococcus granulosus adenosine deaminase 0.0201 0.2368 0.2786
Trichomonas vaginalis ribokinase, putative 0.002 0.0094 0.0145
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0232 0.0269
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.034 0.0547
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.1037 0.1671
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0232 0.0416
Schistosoma mansoni adenosine deaminase 0.0201 0.2368 0.2775
Echinococcus granulosus neuropeptide FF receptor 2 0.0078 0.0826 0.0969
Brugia malayi STAT protein, DNA binding domain containing protein 0.0131 0.1493 0.2406
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0086 0.008
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0136 0.1545 0.249
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0139
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.006 0.0598 0.0964
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0338 0.0544
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0232 0.0253
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0089 0.0958 0.1544
Loa Loa (eye worm) adenosylhomocysteinase 0.0507 0.6205 1
Onchocerca volvulus 0.0102 0.1128 0.2053
Trypanosoma cruzi ribokinase, putative 0.002 0.0094 0.0152
Brugia malayi Dopamine receptor protein 1 0.0078 0.0826 0.1332
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0232 0.0269
Onchocerca volvulus 0.0078 0.0826 0.1502
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.006 0.0598 0.07
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0004
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0112 0.0152
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0172 0.0168
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0023 0.003
Schistosoma mansoni equilibrative nucleoside transporter 0.0014 0.0023 0.0006
Entamoeba histolytica hypothetical protein 0.0066 0.0676 0.1064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0107 0.1189 0.1893
Entamoeba histolytica hypothetical protein 0.0019 0.0086 0.011
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0062 0.0627 0.1011
Echinococcus multilocularis g protein coupled receptor 0.0078 0.0826 0.0822
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0066 0.0676 0.1084
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0232 0.0374
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0787 0.1262
Brugia malayi follicle stimulating hormone receptor 0.0078 0.0826 0.1332
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0029
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0086 0.0139
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0081 0.0865 0.1388
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0232 0.0374
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0086 0.0082
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0787 0.1026
Leishmania major hypothetical protein, conserved 0.0139 0.1587 0.2557
Brugia malayi G protein-coupled receptor F59B2.13 0.0078 0.0826 0.1332
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0136 0.1545 0.2468
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0136 0.1545 0.249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0042 0.0372 0.06
Echinococcus multilocularis adenosine deaminase 0.0201 0.2368 0.2365
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0089 0.0959 0.0955
Leishmania major hypothetical protein, unknown function 0.0066 0.0676 0.109
Mycobacterium ulcerans beta-lactamase 0.0075 0.0787 0.1268
Schistosoma mansoni Smad4 0.0017 0.0059 0.0048
Echinococcus multilocularis Smad4 0.0017 0.0059 0.0055
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0173 0.2016 0.2012
Trypanosoma cruzi AMP deaminase, putative 0.0335 0.4047 0.6522
Schistosoma mansoni neuropeptide receptor 0.0078 0.0826 0.0954
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0488 0.078
Schistosoma mansoni adenosine kinase 0.0174 0.2026 0.2371
Loa Loa (eye worm) phosphatidylinositol 3 0.0116 0.1305 0.2104
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0507 0.6205 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0066 0.0676 0.109
Schistosoma mansoni protein kinase 0.0015 0.0033 0.0017
Brugia malayi hypothetical protein 0.0163 0.189 0.3045
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Schistosoma mansoni hypothetical protein 0.0078 0.0826 0.0954
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0787 0.1268
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Leishmania major hypothetical protein, conserved 0.0066 0.0676 0.109
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0507 0.6205 0.8255
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0107 0.1189 0.1917
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0107 0.1189 0.7671
Schistosoma mansoni myosin xvIII 0.0078 0.0826 0.0954
Mycobacterium ulcerans hypothetical protein 0.0075 0.0787 0.1268
Plasmodium vivax importin-beta 2, putative 0.0029 0.0207 0.0306
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0028 0.0195 0.0191
Toxoplasma gondii phosphatidylinositol 4-kinase 0.005 0.0475 0.0739
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0014 0.0023 0.0037
Trypanosoma cruzi prolyl endopeptidase 0.0014 0.0018 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0107 0.1189 0.1383
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0078 0.0826 0.0954
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Schistosoma mansoni hypothetical protein 0.0078 0.0826 0.0954
Echinococcus granulosus Na+ dependent nucleoside transporter 0.0343 0.4149 0.4886
Schistosoma mansoni inositol transporter 0.0038 0.0326 0.0364
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0232 0.0374
Brugia malayi MH2 domain containing protein 0.0017 0.0059 0.0095
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0066 0.0676 0.4311
Brugia malayi Adenosine/AMP deaminase family protein 0.0201 0.2368 0.3816
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0768 0.09
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0136 0.1545 0.2468
Echinococcus granulosus dnaJ subfamily B 0.0409 0.4968 0.5851
Loa Loa (eye worm) hypothetical protein 0.0015 0.0029 0.0047
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0488 0.0484
Plasmodium vivax SET domain protein, putative 0.003 0.0228 0.0339
Echinococcus multilocularis neuropeptide receptor A26 0.0078 0.0826 0.0822
Loa Loa (eye worm) hypothetical protein 0.0122 0.138 0.2224
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0026 0.001
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0016 0.005 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0826 0.0822
Leishmania major protein kinase, putative 0.0025 0.0156 0.0252
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0432 0.0488
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0177 0.2062 0.3324
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0232 0.0374
Trichomonas vaginalis esterase, putative 0.0075 0.0787 0.1262
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0112 0.0152
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0826 0.0969
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0078 0.0826 0.0822
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0112 0.0152
Schistosoma mansoni neuropeptide f receptor 76f 0.0078 0.0826 0.0954
Brugia malayi CXXC zinc finger family protein 0.0029 0.0206 0.0331
Onchocerca volvulus 0.0029 0.0206 0.0368
Schistosoma mansoni fkbp-rapamycin associated protein 0.0066 0.0676 0.0777
Plasmodium vivax hypothetical protein 0.0066 0.0676 0.1064
Leishmania major phosphatidylinositol 4-kinase, putative 0.0116 0.1305 0.2104
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0029 0.004
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0107 0.1189 0.1186
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0046 0.0046
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0787 0.1026
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0081
Trypanosoma cruzi oligopeptidase b 0.0014 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0081
Brugia malayi nuclear hormone receptor 0.0031 0.0232 0.0374
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0096 0.0154
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0112 0.018
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0338 0.0538
Brugia malayi Dopamine receptor protein 2 0.0078 0.0826 0.1332
Leishmania major nucleoside transporter 1, putative 0.0014 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0066 0.0676 0.109
Echinococcus multilocularis geminin 0.0169 0.1968 0.1964
Mycobacterium tuberculosis Adenosine kinase 0.002 0.0094 0.0102
Loa Loa (eye worm) hypothetical protein 0.0038 0.0326 0.0525
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0107 0.1189 0.1917
Echinococcus multilocularis neuropeptide receptor 0.0078 0.0826 0.0822
Onchocerca volvulus 0.0139 0.1587 0.2891
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0059 0.0055
Echinococcus granulosus peptide allatostatin:somatostatin 0.0078 0.0826 0.0969
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0066 0.0676 0.0777
Loa Loa (eye worm) beta-lactamase 0.0075 0.0787 0.1268
Echinococcus granulosus intermediate filament protein 0.0027 0.0184 0.0211
Echinococcus granulosus microtubule associated protein 2 0.0689 0.8487 1
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0089 0.0959 0.154
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0078 0.0826 0.0822
Brugia malayi hypothetical protein 0.0019 0.0086 0.0139
Loa Loa (eye worm) hypothetical protein 0.0044 0.0403 0.065
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0028 0.0024
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0232 0.0269
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.034 0.052
Trypanosoma cruzi nucleoside transporter-like, putative 0.0014 0.0023 0.0037
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0112 0.018
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0389 0.0627
Onchocerca volvulus 0.003 0.0228 0.0408
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0026 0.0042
Trypanosoma brucei adenosine kinase, putative 0.0174 0.2026 0.3265
Plasmodium vivax hypothetical protein, conserved 0.0066 0.0676 0.1064
Trypanosoma cruzi nucleobase transporter, putative 0.0014 0.0023 0.0037
Mycobacterium tuberculosis Conserved protein 0.0075 0.0787 0.1026
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0066 0.0676 0.1064
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0507 0.6205 1
Onchocerca volvulus 0.0078 0.0826 0.1502
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0078 0.0826 0.0969
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0028 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0078 0.0826 0.0969
Loa Loa (eye worm) hypothetical protein 0.0066 0.0676 0.109
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0061 0.0057
Brugia malayi hypothetical protein 0.0078 0.0826 0.1332
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0139
Loa Loa (eye worm) hypothetical protein 0.0031 0.0232 0.0374
Schistosoma mansoni cpg binding protein 0.003 0.0226 0.0246
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0047 0.0432 0.0689
Loa Loa (eye worm) hypothetical protein 0.0201 0.2368 0.3816
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0066 0.0676 0.0672
Echinococcus granulosus death domain containing protein 0.0014 0.0026 0.0026
Onchocerca volvulus Putative pyridoxal kinase 0.002 0.0094 0.0165
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0028 0.0195 0.0314
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0094 0.1019 0.1642
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0066 0.0676 0.109
Mycobacterium tuberculosis Conserved hypothetical protein 0.0066 0.0676 0.0878
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0136 0.1545 0.249
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0172 0.0271
Leishmania major ribokinase, putative 0.002 0.0094 0.0152
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0159 0.1842 0.2964
Schistosoma mansoni coup transcription factor 0.0031 0.0232 0.0253
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0086 0.0139
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0449 0.5478 0.8828
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0086 0.0132
Mycobacterium ulcerans carbohydrate kinase CbhK 0.002 0.0094 0.0152
Schistosoma mansoni hypothetical protein 0.0028 0.0195 0.0209
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0028 0.0028
Echinococcus multilocularis concentrative Na+ nucleoside cotransporter 0.0343 0.4149 0.4147
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0172 0.0277
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0016 0.005 0.0074
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0028 0.0195 0.0225
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0787 0.1268
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0078 0.0826 0.0954
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.005 0.0038
Echinococcus granulosus tm gpcr rhodopsin 0.0078 0.0826 0.0969
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0157 0.1819 0.291
Schistosoma mansoni opsin-like receptor 0.0078 0.0826 0.0954
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0107 0.1189 0.1911
Mycobacterium leprae conserved hypothetical protein 0.0066 0.0676 0.1084
Schistosoma mansoni neuropeptide receptor 0.0078 0.0826 0.0954
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0014 0.0018 0.0022
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0066 0.0676 0.109
Mycobacterium tuberculosis Possible exported protein 0.0612 0.7513 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0066 0.0676 0.109
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0165 0.0267
Schistosoma mansoni smad 0.0017 0.0059 0.0048
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.006 0.0598 0.0938
Leishmania major nucleobase transporter 0.0014 0.0023 0.0037
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0061 0.0067
Schistosoma mansoni smad1 5 8 and 0.0017 0.0059 0.0048
Brugia malayi ORL1-like opioid receptor 0.0078 0.0826 0.1332
Echinococcus multilocularis neuropeptides capa receptor 0.0078 0.0826 0.0822
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0066 0.0676 0.0672
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0017 0.0059 0.0065
Entamoeba histolytica Ran family GTPase 0.0021 0.0112 0.0152
Brugia malayi nuclear receptor NHR-88 0.0015 0.0028 0.0045
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0338 0.0538
Schistosoma mansoni biogenic amine (5HT) receptor 0.0078 0.0826 0.0954
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0086 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0232 0.0374
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0165 0.0238
Brugia malayi hypothetical protein 0.0033 0.0265 0.0428
Brugia malayi hypothetical protein 0.0015 0.0028 0.0045
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0768 0.0764
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0019 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0037
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0059 0.0048
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0004 0.0007
Leishmania major nucleobase transporter 0.0014 0.0023 0.0037
Giardia lamblia Hypothetical protein 0.0081 0.0865 0.5546
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0488 0.0555
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0172 0.0277
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0066 0.0676 0.0777
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0066 0.0676 0.109
Loa Loa (eye worm) phosphatidylinositol 3 0.0041 0.0359 0.0579
Entamoeba histolytica nucleoside transporter, putative 0.0081 0.0865 0.1369
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0078 0.0826 0.0822
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0014 0.0023 0.003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.1037 0.1217
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma cruzi adenosine kinase, putative 0.0174 0.2026 0.3265
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0059 0.0064
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0136 0.1545 0.2485
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0338 0.0334
Entamoeba histolytica fructokinase, putative 0.002 0.0094 0.0123
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0207 0.0334
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0389 0.0454
Brugia malayi hypothetical protein 0.0036 0.0292 0.047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.0826 0.0954
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0136 0.1545 0.2485
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.2062 0.2059
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0232 0.0374
Brugia malayi Flap endonuclease-1 0.0026 0.0172 0.0277
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0826 0.0954
Loa Loa (eye worm) phosphatidylinositol 3 0.0449 0.5478 0.8828
Echinococcus multilocularis solute carrier family 5 0.0038 0.0326 0.0322
Brugia malayi ecdysteroid receptor 0.0031 0.0232 0.0374
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0066 0.0676 0.109
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0232 0.0269
Echinococcus granulosus neuropeptide Y receptor 0.0078 0.0826 0.0969
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0046 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0086 0.0132
Plasmodium falciparum importin beta, putative 0.0029 0.0207 0.0306
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0096 0.0091
Echinococcus granulosus prolyl endopeptidase 0.0014 0.0018 0.0016
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0028 0.0045
Giardia lamblia GTOR 0.0066 0.0676 0.4311
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0338 0.0544
Trypanosoma brucei AMP deaminase, putative 0.0335 0.4047 0.6522
Brugia malayi RNA, U transporter 1 0.0082 0.0873 0.1407
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0232 0.0374
Trypanosoma brucei adenosine transporter 2, putative 0.0014 0.0023 0.0037
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0206 0.0331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0029 0.0018
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0136 0.1545 0.1803
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0116 0.1305 0.2081
Onchocerca volvulus Adenosine deaminase homolog 0.0201 0.2368 0.4318
Entamoeba histolytica kinase, PfkB family 0.002 0.0094 0.0123
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0078 0.0826 0.1332
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0014 0.0022
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0184 0.0296
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0078 0.0826 0.0954
Brugia malayi AKH receptor 0.0078 0.0826 0.1332
Loa Loa (eye worm) hypothetical protein 0.0027 0.0184 0.0296
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0061 0.0067
Schistosoma mansoni hypothetical protein 0.0078 0.0826 0.0954
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0078 0.0826 0.0969
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0046 0.0049
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0028 0.0028
Trichomonas vaginalis ribokinase, putative 0.002 0.0094 0.0145
Echinococcus multilocularis neuropeptides capa receptor 0.0078 0.0826 0.0822
Plasmodium falciparum adenosylhomocysteinase 0.0507 0.6205 1
Onchocerca volvulus 0.0078 0.0826 0.1502
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0086 0.0082
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0338 0.0544
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0066 0.0676 0.1064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0136 0.1545 0.249
Mycobacterium ulcerans adenosine deaminase 0.0201 0.2368 0.3816
Schistosoma mansoni hypothetical protein 0.0409 0.4968 0.5845
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0066 0.0676 0.109
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.1037 0.1671
Loa Loa (eye worm) hypothetical protein 0.0014 0.0019 0.003
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0507 0.6205 1
Schistosoma mansoni sodium/solute symporter 0.0038 0.0326 0.0364
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0152
Trypanosoma brucei adenosine transporter 2 0.0014 0.0023 0.0037
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0086 0.0082
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0086 0.0096
Echinococcus granulosus smad 0.0017 0.0059 0.0064
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0136 0.1545 0.2485
Echinococcus granulosus serine protein kinase ATM 0.0066 0.0676 0.0792
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0232 0.0374
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0067 0.0688 0.0684
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0232 0.0374
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0307 0.37 0.5964
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0488 0.0786
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0141 0.1609 0.2593
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0016 0.005 0.0074
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.002 0.0094 0.0102
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0086 0.008
Echinococcus granulosus allatostatin A receptor 0.0078 0.0826 0.0969
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0081 0.0865 0.0861
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.006 0.0598 0.0938
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0136 0.1545 0.249
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0335 0.4047 0.6522
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0019 0.0001
Echinococcus multilocularis snurportin 1 0.0307 0.37 0.3698
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0066 0.0676 0.0777
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0066 0.0676 0.109
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0081 0.0865 0.1572
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0338 0.0544
Brugia malayi G-protein coupled receptor 0.0078 0.0826 0.1332
Trypanosoma brucei prolyl endopeptidase 0.0014 0.0018 0.0029
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0086 0.008
Echinococcus multilocularis lamin 0.0027 0.0184 0.0179
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0116 0.1305 0.2104
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0066 0.0676 0.1064
Loa Loa (eye worm) hypothetical protein 0.006 0.0598 0.0964
Loa Loa (eye worm) prolyl oligopeptidase 0.0014 0.0018 0.0029
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0338 0.0538
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0112 0.018
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0078 0.0826 0.0954
Entamoeba histolytica AMP deaminase, putative 0.0335 0.4047 0.6512
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0017 0.0059 0.0065
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0359 0.0572
Echinococcus granulosus concentrative Na nucleoside cotransporter 0.0343 0.4149 0.4886
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0046 0.0074
Trypanosoma cruzi adenosine kinase, putative 0.002 0.0094 0.0152
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0488 0.078
Brugia malayi Protein kinase domain containing protein 0.0015 0.0036 0.0057
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.2971 0.4789
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0507 0.6205 1
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0015 0.0029 0.0045
Loa Loa (eye worm) STAT protein 0.0131 0.1493 0.2406
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0019 0.0017
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0107 0.1189 0.1911
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0826 0.0969
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.0201 0.2368 0.3812
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.002 0.0094 0.0123
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0165 0.0238
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0338 0.0517
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0488 0.0786
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0078 0.0826 0.0822
Schistosoma mansoni neuropeptide receptor 0.0078 0.0826 0.0954
Leishmania major adenosine kinase, putative 0.0174 0.2026 0.3265
Brugia malayi GMP synthase 0.006 0.0598 0.0964
Echinococcus granulosus adenosylhomocysteinase 0.0507 0.6205 0.731
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0028 0.0028
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.005 0.0081
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.002 0.0094 0.0123
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.246 0.3964
Brugia malayi hypothetical protein 0.0015 0.0028 0.0045
Onchocerca volvulus 0.0015 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0081 0.0865 0.1394
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0338 0.0538
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0338 0.0517
Echinococcus granulosus single minded 2 0.0039 0.0339 0.0395
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0826 0.0822
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0078 0.0826 0.0954
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0107 0.1189 0.1893
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0507 0.6205 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0066 0.0676 0.109
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0787 0.1268
Leishmania major tagatose-6-phosphate kinase-like protein 0.002 0.0094 0.0152
Loa Loa (eye worm) hypothetical protein 0.0163 0.189 0.3045
Brugia malayi hypothetical protein 0.0014 0.0023 0.0037
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0335 0.4047 0.6522
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0078 0.0826 0.0822
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0078 0.0826 0.0822
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0066 0.0676 0.109
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0019 0.0023
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0232 0.0228
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.2807 0.2804
Brugia malayi hypothetical protein 0.0122 0.137 0.2208
Brugia malayi hypothetical protein 0.0019 0.0086 0.0139
Brugia malayi neuropeptide F receptor 0.0078 0.0826 0.1332
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0787 0.1026
Trypanosoma brucei AMP deaminase, putative 0.0335 0.4047 0.6522
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0086 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0232 0.0374
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0019 0.0017
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0028 0.0024
Loa Loa (eye worm) prolyl oligopeptidase 0.0173 0.2016 0.3248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0016 0.005 0.0052
Giardia lamblia Phosphatidylinositol 4-kinase 0.0116 0.1305 0.8432
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0009 0.0005
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0058 0.0575 0.0927
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0232 0.0269
Entamoeba histolytica adenosylhomocysteinase, putative 0.0507 0.6205 1
Echinococcus granulosus AMP deaminase 2 0.0335 0.4047 0.4765
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0078 0.0826 0.0822
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0016 0.005 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0029 0.004
Entamoeba histolytica AMP deaminase, putative 0.0335 0.4047 0.6512
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0207 0.0306
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0232 0.0374
Entamoeba histolytica hypothetical protein 0.0066 0.0676 0.1064
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0059 0.0095
Onchocerca volvulus Prolyl endopeptidase homolog 0.0014 0.0018 0.0025
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0086 0.0082
Leishmania major NAD synthase, putative 0.0016 0.005 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0228 0.0223
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.4968 0.4966
Echinococcus multilocularis g-protein coupled receptor 0.0078 0.0826 0.0822
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0026 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0061 0.0051
Loa Loa (eye worm) hypothetical protein 0.0066 0.0676 0.109
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0014 0.0018 0.0022
Leishmania major adenosine kinase-like protein 0.002 0.0094 0.0152
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0028 0.0028
Onchocerca volvulus AMP deaminase 2 homolog 0.0335 0.4047 0.7386
Schistosoma mansoni neuropeptide F-like receptor 0.0078 0.0826 0.0954
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0107 0.1189 0.1893
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0019 0.0017
Echinococcus granulosus tm gpcr rhodopsin 0.0078 0.0826 0.0969
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0089 0.0959 0.154
Onchocerca volvulus 0.0078 0.0826 0.1502
Loa Loa (eye worm) hypothetical protein 0.0196 0.2306 0.3717
Onchocerca volvulus 0.0036 0.0297 0.0534
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0455 0.0516
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0078 0.0826 0.1332
Trypanosoma brucei AMP deaminase, putative 0.0335 0.4047 0.6522
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0787 0.1026
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0066 0.0676 0.1064
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Trypanosoma cruzi AMP deaminase, putative 0.0335 0.4047 0.6522
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0172 0.0249
Trichomonas vaginalis adenosine deaminase, putative 0.0201 0.2368 0.3812
Echinococcus granulosus expressed protein 0.0373 0.452 0.5323
Onchocerca volvulus 0.002 0.0094 0.0165
Echinococcus multilocularis g protein coupled receptor 0.0078 0.0826 0.0822
Brugia malayi hypothetical protein 0.0036 0.0292 0.047
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0046 0.0074
Schistosoma mansoni netrin receptor unc5 0.0014 0.0026 0.001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0787 0.0908
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Schistosoma mansoni intermediate filament proteins 0.0027 0.0184 0.0196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0826 0.0954
Schistosoma mansoni hypothetical protein 0.0048 0.045 0.051
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0045
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0141 0.1609 0.1605
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0232 0.0416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0676 0.1084
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0046 0.0042
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0488 0.0786
Trypanosoma brucei oligopeptidase b 0.0014 0.0018 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0232 0.0374
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0047 0.0433 0.0691
Mycobacterium leprae Probable adenosine kinase adk 0.002 0.0094 0.0145
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0826 0.0969
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0094 0.1019 0.1642
Schistosoma mansoni lamin 0.0027 0.0184 0.0196
Onchocerca volvulus 0.0078 0.0826 0.1502
Trypanosoma cruzi adenosine kinase, putative 0.0174 0.2026 0.3265
Loa Loa (eye worm) phosphatidylinositol 3 0.0066 0.0676 0.109
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0086 0.0139
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0058 0.0575 0.0658
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0141 0.1609 0.2571
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.1037 0.1217
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0086 0.0096
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0029 0.0047
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0026 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.005 0.0081
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0019 0.0017
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Echinococcus multilocularis acylamino acid releasing enzyme 0.0014 0.0018 0.0014
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0787 0.0908
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0086 0.0096
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0139
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0787 0.0783
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0086 0.0082
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0066 0.0676 0.1064
Echinococcus granulosus biogenic amine 5HT receptor 0.0078 0.0826 0.0969
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0826 0.0822
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0826 0.0822
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.002 0.0094 0.0106
Loa Loa (eye worm) hypothetical protein 0.0032 0.0247 0.0398
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0826 0.0954
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0029
Trichomonas vaginalis ran, putative 0.0021 0.0112 0.0173
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0019 0.0023
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0232 0.0253
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0029 0.004
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0026 0.0026
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0014 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0081
Loa Loa (eye worm) hypothetical protein 0.0078 0.0826 0.1332
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0136 0.1545 0.1803
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0094 0.0145
Echinococcus granulosus geminin 0.0169 0.1968 0.2315
Trichomonas vaginalis ribokinase, putative 0.002 0.0094 0.0145

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 2.49 uM Inhibitory activity against thermolysin using N-[3-(2-furyl)acryloyl]-Gly-l-leucineamide (FA-Gly-l-Leu-NH2) as substrate ChEMBL. 12951085
Ki (binding) = 2.49 uM Inhibitory activity against thermolysin using N-[3-(2-furyl)acryloyl]-Gly-l-leucineamide (FA-Gly-l-Leu-NH2) as substrate ChEMBL. 12951085
Ki (binding) = 10.6 uM Inhibitory activity against thermolysin ChEMBL. 12951085
Ki (binding) = 10.6 uM Inhibitory activity against thermolysin ChEMBL. 12951085
Km/Kcat (binding) = 13.6 uM s-1 Ratio of Km to that of Kcat against thermolysin ChEMBL. 12951085

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.