Detailed information for compound 22627

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 247.333 | Formula: C15H21NO2
  • H donors: 1 H acceptors: 1 LogP: 2.59 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)[C@H](c1cccc(c1)C)C1CCCCN1
  • InChi: 1S/C15H21NO2/c1-11-6-5-7-12(10-11)14(15(17)18-2)13-8-3-4-9-16-13/h5-7,10,13-14,16H,3-4,8-9H2,1-2H3/t13?,14-/m1/s1
  • InChiKey: NRBMYZAWNJOHPY-ARLHGKGLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax apical sushi protein, putative 0.0043 0.0136 0.0831
Brugia malayi hypothetical protein 0.0019 0.0014 0.0014
Echinococcus granulosus snurportin 1 0.0342 0.1683 0.1683
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.1291
Onchocerca volvulus 0.0023 0.0034 0.0044
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.0011 0.0011
Brugia malayi Stress-activated protein kinase jnk-1 0.0463 0.2312 0.2312
Brugia malayi Intermediate filament tail domain containing protein 0.0117 0.0522 0.0522
Onchocerca volvulus Peroxidasin homolog 0.013 0.0588 0.1117
Brugia malayi Nuclear hormone receptor E75 0.0057 0.0212 0.0212
Brugia malayi Nuclear hormone receptor-like 1 0.0122 0.0544 0.0544
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0016 0.0005
Onchocerca volvulus 0.0057 0.0212 0.0389
Onchocerca volvulus 0.0043 0.0136 0.0242
Trypanosoma brucei cAMP-specific phosphodiesterase 0.1047 0.5334 0.5333
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1949 1 1
Loa Loa (eye worm) hypothetical protein 0.0949 0.4825 0.4825
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.013 0.0587 0.0587
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0061 0.0231 0.0229
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0057 0.0212 0.0288
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0152 0.0701 0.07
Brugia malayi hypothetical protein 0.0022 0.0031 0.0031
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Treponema pallidum chemotaxis histidine kinase (cheA) 0.003 0.0071 0.0391
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0069 0.027 0.027
Mycobacterium ulcerans beta-lactamase 0.0036 0.0099 0.0503
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Trichomonas vaginalis sucrase-isomaltase, putative 0.013 0.0587 0.1077
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0061 0.0231 0.0231
Brugia malayi photoreceptor-specific nuclear receptor 0.0122 0.0544 0.0544
Schistosoma mansoni hypothetical protein 0.0017 0.0004 0.0006
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0037 0.0037
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0036 0.0099 0.0099
Loa Loa (eye worm) NADH dehydrogenase subunit 1 0.0037 0.0105 0.0105
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0081 0.0169
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0122 0.0544 0.0544
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0016 0.0005
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0012 0.0009
Echinococcus granulosus mitogen activated protein kinase 11 0.1949 1 1
Onchocerca volvulus 0.0022 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0064 0.0247 0.0247
Onchocerca volvulus 0.002 0.0016 0.001
Loa Loa (eye worm) hypothetical protein 0.0109 0.0482 0.0482
Echinococcus multilocularis carboxylesterase 5A 0.0216 0.1033 0.1033
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0056 0.0207 0.0206
Brugia malayi heat shock protein 90 0.003 0.0071 0.0071
Onchocerca volvulus 0.0043 0.0136 0.0242
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0061 0.0231 0.118
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0031 0.0031
Leishmania major importin beta-1 subunit, putative 0.0026 0.0049 0.0048
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0257 0.035
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Leishmania major hypothetical protein, conserved 0.0152 0.0701 0.07
Brugia malayi Pre-SET motif family protein 0.0034 0.009 0.009
Plasmodium falciparum heat shock protein 90 0.003 0.0071 0.0379
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0152 0.0701 0.0701
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Schistosoma mansoni alpha-glucosidase 0.0504 0.2522 0.3431
Loa Loa (eye worm) hypothetical protein 0.0049 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0043 0.0135 0.0135
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.003 0.0071 0.0341
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0099 0.032
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0122 0.0544 0.0544
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0048 0.0165 0.0285
Schistosoma mansoni steroid hormone receptor ad4bp 0.0122 0.0544 0.074
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.0011
Brugia malayi hypothetical protein 0.0474 0.2366 0.2366
Schistosoma mansoni lamin 0.0117 0.0522 0.071
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.0071 0.0068
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.0698
Leishmania major kinesin, putative 0.004 0.0123 0.0122
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0123 0.012
Echinococcus granulosus mitogen activated protein kinase 14 0.1949 1 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0107 0.037
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0257 0.035
Trichomonas vaginalis heat shock protein, putative 0.003 0.0071 0.0108
Echinococcus multilocularis N chimaerin 0.0023 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0004
Trypanosoma brucei calpain-like protein, putative 0.004 0.0123 0.012
Schistosoma mansoni NADH dehydrogenase subunit 1 0.0037 0.0105 0.0142
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.003 0.0071 0.0341
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0016 0.0022
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0016 0.0016
Mycobacterium ulcerans NADH dehydrogenase subunit H 0.0136 0.062 0.3489
Entamoeba histolytica diacylglycerol kinase, putative 0.0023 0.0034 0.0304
Trypanosoma cruzi hypothetical protein, conserved 0.0152 0.0701 0.0698
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0152 0.0701 0.1291
Loa Loa (eye worm) AGC/PKG protein kinase 0.0059 0.022 0.022
Echinococcus multilocularis nuclear receptor nhr 48 0.0057 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0342 0.1686 0.1686
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Plasmodium vivax hypothetical protein, conserved 0.0325 0.1598 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0057 0.0208 0.0208
Brugia malayi diacylglycerol kinase 0.0023 0.0034 0.0034
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Echinococcus multilocularis mitogen activated protein kinase 11 0.1949 1 1
Onchocerca volvulus Bile acid receptor homolog 0.028 0.1362 0.2618
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0011
Echinococcus multilocularis expressed conserved protein 0.0059 0.022 0.022
Trypanosoma cruzi kinesin, putative 0.004 0.0123 0.012
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0152 0.0701 0.4347
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0294 0.0294
Brugia malayi Cathepsin L-like precursor 0.002 0.0016 0.0016
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0264 0.1454
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0599 0.0816
Brugia malayi hypothetical protein 0.0064 0.0247 0.0247
Schistosoma mansoni zinc finger protein 0.0057 0.0212 0.0288
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0152 0.0701 0.0954
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.013 0.1986
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0016 0.0005
Schistosoma mansoni protein kinase C 0.0023 0.0034 0.0046
Toxoplasma gondii hypothetical protein 0.0019 0.0011 0.0016
Onchocerca volvulus 0.0022 0.0031 0.0039
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0231 0.0409
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0105 0.0456 0.0456
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.003 0.0071 0.0108
Loa Loa (eye worm) hypothetical protein 0.0043 0.0136 0.0136
Trypanosoma brucei heat shock protein, putative 0.003 0.0071 0.0068
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Brugia malayi Blistered cuticle protein 3 0.013 0.0588 0.0588
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0099 0.0511
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0152 0.0701 0.1291
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0023 0.0034 0.0034
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.005 0.0218
Schistosoma mansoni endoplasmin 0.003 0.0071 0.0097
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0415 0.0415
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0165 0.0285
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0122 0.0544 0.0544
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.003 0.0071 0.035
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0463 0.2312 0.2312
Loa Loa (eye worm) runx1 0.0127 0.0574 0.0574
Entamoeba histolytica heat shock protein 90, putative 0.003 0.0071 0.0963
Trypanosoma brucei PAB1-binding protein , putative 0.0039 0.0114 0.0111
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0059 0.022 0.0477
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0099 0.0161
Echinococcus granulosus survival motor neuron protein 1 0.0474 0.2366 0.2366
Loa Loa (eye worm) hypothetical protein 0.0122 0.0544 0.0544
Loa Loa (eye worm) hypothetical protein 0.0064 0.0247 0.0247
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0264 0.0264
Trypanosoma cruzi hypothetical protein, conserved 0.0152 0.0701 0.0698
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.003 0.0071 0.0341
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.1047 0.5334 1
Schistosoma mansoni pyruvate dehydrogenase 0.0543 0.2724 0.3706
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0188 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.003 0.0071 0.0068
Trichomonas vaginalis ran, putative 0.0024 0.0037 0.0043
Toxoplasma gondii hypothetical protein 0.0325 0.1598 0.3508
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.019 0.09 0.09
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0068 0.0266 0.0263
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0722 0.3651 0.6837
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0543 0.2724 0.2724
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0105 0.0456 0.0621
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0695 0.0695
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0264 0.0262
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0017 0.0004 0.0004
Brugia malayi exodeoxyribonuclease III family protein 0.0061 0.0231 0.0231
Brugia malayi Animal haem peroxidase family protein 0.013 0.0588 0.0588
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1047 0.5334 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Trypanosoma brucei heat shock protein 90, putative 0.003 0.0071 0.0068
Entamoeba histolytica heat shock protein 90, putative 0.003 0.0071 0.0963
Leishmania major hypothetical protein, conserved 0.0017 0.0003 0.0002
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Onchocerca volvulus 0.0043 0.0136 0.0242
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0036 0.0104 0.0169
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0231 0.1388
Loa Loa (eye worm) animal heme peroxidase 0.013 0.0588 0.0588
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0061 0.0231 0.0231
Loa Loa (eye worm) calpain 5 0.004 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0054 0.0197 0.0197
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0152 0.0701 0.0701
Loa Loa (eye worm) hypothetical protein 0.0115 0.0511 0.0511
Echinococcus multilocularis cysteine protease 0.002 0.0016 0.0016
Loa Loa (eye worm) heat shock protein 90 0.003 0.0071 0.0071
Echinococcus multilocularis heat shock protein 90 0.003 0.0071 0.0071
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0294 0.0294
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0033 0.0087 0.0087
Chlamydia trachomatis DNA gyrase subunit B 0.003 0.0071 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0061 0.0231 0.3769
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0122 0.0544 0.0544
Trypanosoma brucei heat shock protein, putative 0.003 0.0071 0.0068
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0264 0.0264
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Onchocerca volvulus 0.0026 0.005 0.0075
Onchocerca volvulus 0.0043 0.0136 0.0242
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0099 0.0099
Loa Loa (eye worm) beta-lactamase 0.0036 0.0099 0.0099
Brugia malayi hypothetical protein 0.0043 0.0136 0.0136
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0123 0.012
Onchocerca volvulus Dual oxidase homolog 0.013 0.0588 0.1117
Echinococcus granulosus FTZ F1 alpha 0.0122 0.0544 0.0544
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0033 0.0087 0.0087
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0139 0.0636 0.0636
Echinococcus granulosus neuroligin 0.0036 0.0104 0.0104
Loa Loa (eye worm) acetyltransferase 0.0151 0.0695 0.0695
Loa Loa (eye worm) norepinephrine transporter 0.0109 0.0482 0.0482
Echinococcus granulosus calcium activated potassium channel 0.0017 0.0002 0.0002
Echinococcus granulosus neutral alpha glucosidase AB 0.013 0.0587 0.0587
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0257 0.035
Echinococcus multilocularis thyroid hormone receptor alpha 0.0261 0.1265 0.1265
Schistosoma mansoni ferritin 0.0027 0.0054 0.0074
Brugia malayi AMP-binding enzyme family protein 0.0026 0.005 0.005
Brugia malayi Carboxylesterase family protein 0.0216 0.1033 0.1033
Brugia malayi Cathepsin L-like precursor 0.002 0.0016 0.0016
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0152 0.0701 0.0698
Brugia malayi Carboxylesterase family protein 0.0036 0.0104 0.0104
Onchocerca volvulus 0.002 0.0016 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0122 0.0544 0.0544
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.1047 0.5334 0.5334
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1047 0.5334 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0039 0.0114 0.065
Echinococcus granulosus Diacylglycerol kinase theta 0.0023 0.0034 0.0034
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0044 0.0143 0.0243
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0122 0.0544 0.0544
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0013 0.0013
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0056 0.0207 0.0205
Echinococcus multilocularis snurportin 1 0.0342 0.1683 0.1683
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0294 0.04
Echinococcus granulosus cGMP dependent protein kinase 0.0059 0.022 0.022
Onchocerca volvulus 0.0043 0.0136 0.0242
Echinococcus multilocularis mitogen activated protein kinase 14 0.1949 1 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0231 0.1428
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) 0.0136 0.062 0.3495
Plasmodium falciparum phosphodiesterase delta, putative 0.0152 0.0701 0.4347
Chlamydia trachomatis DNA gyrase subunit B 0.003 0.0071 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0122 0.0544 0.0544
Entamoeba histolytica hypothetical protein 0.0023 0.0034 0.0304
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0016 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Schistosoma mansoni calpain C (C02 family) 0.004 0.0123 0.0168
Onchocerca volvulus DNA topoisomerase 2 homolog 0.003 0.0071 0.0116
Toxoplasma gondii MAPEG family protein 0.0123 0.0549 0.12
Onchocerca volvulus 0.0043 0.0136 0.0242
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Echinococcus granulosus protein kinase c iota type 0.0033 0.0087 0.0087
Brugia malayi Cytochrome P450 family protein 0.0019 0.0012 0.0012
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0016 0.0005
Schistosoma mansoni endoplasmin 0.003 0.0071 0.0097
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.003 0.0071 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0122 0.0544 0.0544
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0036 0.0104 0.0141
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0017 0.0004 0.0001
Loa Loa (eye worm) TOPoisomerase family member 0.003 0.0071 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0152 0.0701 0.0698
Trypanosoma cruzi hypothetical protein, conserved 0.013 0.0587 0.0584
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Loa Loa (eye worm) hypothetical protein 0.0109 0.0482 0.0482
Giardia lamblia Heat shock protein HSP 90-alpha 0.003 0.0071 0.0208
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0099 0.0097
Onchocerca volvulus 0.0036 0.0104 0.018
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0036 0.0104 0.0104
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.0011
Leishmania major cysteine peptidase A (CPA) 0.002 0.0016 0.0015
Brugia malayi Carboxylesterase family protein 0.0216 0.1033 0.1033
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0587 0.1077
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1047 0.5334 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0049 0.0067
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0019 0.0011 0.0011
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0477 0.2384 0.2384
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.1291
Brugia malayi Doublecortin family protein 0.0022 0.0031 0.0031
Onchocerca volvulus 0.0043 0.0136 0.0242
Loa Loa (eye worm) hypothetical protein 0.0039 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.0011 0.0011
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Brugia malayi Endoplasmin precursor 0.003 0.0071 0.0071
Brugia malayi hypothetical protein 0.0296 0.1448 0.1448
Mycobacterium ulcerans putative regulatory protein 0.0325 0.1598 0.9103
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0013 0.0017
Brugia malayi RhoGAP domain containing protein 0.0023 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Schistosoma mansoni apoferritin-2 0.0027 0.0054 0.0074
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0057 0.0212 0.0389
Loa Loa (eye worm) hypothetical protein 0.0053 0.0188 0.0188
Echinococcus multilocularis lysosomal alpha glucosidase 0.0585 0.2943 0.2943
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0056 0.0207 0.0205
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0043 0.0136 0.0136
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0099 0.0511
Mycobacterium tuberculosis Probable two component sensor kinase 0.003 0.0071 0.035
Toxoplasma gondii cathepsin CPL 0.002 0.0016 0.0028
Trypanosoma brucei heat shock protein, putative 0.003 0.0071 0.0068
Brugia malayi hypothetical protein 0.0043 0.0136 0.0136
Schistosoma mansoni thyroid hormone receptor 0.0261 0.1265 0.1721
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0099 0.0511
Trypanosoma cruzi PAB1-binding protein , putative 0.0039 0.0114 0.0111
Echinococcus multilocularis lysosomal alpha glucosidase 0.0585 0.2943 0.2943
Echinococcus granulosus acetylcholinesterase 0.0216 0.1033 0.1033
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0016 0.0032
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.004 0.0123 0.0471
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0188 0.0188
Brugia malayi Steroid receptor seven-up type 2 0.0122 0.0544 0.0544
Echinococcus multilocularis cysteine protease 0.002 0.0016 0.0016
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.003 0.0071 0.0391
Schistosoma mansoni ferritin light chain 0.0027 0.0054 0.0074
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0081 0.0081
Loa Loa (eye worm) thymidylate synthase 0.004 0.0123 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0122 0.0544 0.0544
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Echinococcus granulosus carboxylesterase 5A 0.0216 0.1033 0.1033
Brugia malayi Glycosyl hydrolases family 31 protein 0.0048 0.0165 0.0165
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1949 1 1
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0048 0.0165 0.0299
Loa Loa (eye worm) PDE1B protein 0.0152 0.0701 0.0701
Loa Loa (eye worm) hypothetical protein 0.0043 0.0136 0.0136
Brugia malayi beta-lactamase family protein 0.0036 0.0099 0.0099
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0123 0.012
Brugia malayi PHD-finger family protein 0.0033 0.0085 0.0085
Leishmania major cathepsin L-like protease 0.002 0.0016 0.0015
Onchocerca volvulus 0.0036 0.0104 0.018
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0135 0.0615 0.0837
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.009 0.0122
Mycobacterium tuberculosis Two component sensor kinase MprB 0.003 0.0071 0.035
Loa Loa (eye worm) carboxylesterase 0.0216 0.1033 0.1033
Leishmania major hypothetical protein, conserved 0.0039 0.0114 0.0113
Schistosoma mansoni nuclear receptor 0.0057 0.0212 0.0288
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0099 0.0503
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0023 0.0034 0.0046
Loa Loa (eye worm) hypothetical protein 0.0064 0.0247 0.0247
Leishmania major cathepsin L-like protease 0.002 0.0016 0.0015
Onchocerca volvulus Peroxidasin homolog 0.013 0.0588 0.1117
Loa Loa (eye worm) hypothetical protein 0.0122 0.0544 0.0544
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0122 0.0544 0.074
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.4373
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Treponema pallidum sodium- and chloride- dependent transporter 0.0109 0.0482 1
Schistosoma mansoni hypothetical protein 0.0023 0.0033 0.0045
Loa Loa (eye worm) hypothetical protein 0.0036 0.0099 0.0099
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0033 0.0087 0.0087
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0152 0.0701 0.0701
Brugia malayi steroid hormone receptor 0.0122 0.0544 0.0544
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0099 0.0135
Schistosoma mansoni ran 0.0024 0.0037 0.005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1047 0.5334 1
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0266 0.0362
Echinococcus multilocularis mitogen activated protein kinase 0.0068 0.0266 0.0266
Echinococcus multilocularis protein kinase c iota type 0.0033 0.0087 0.0087
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.0011 0.0011
Onchocerca volvulus 0.0122 0.0544 0.1033
Trypanosoma cruzi DNA topoisomerase II, putative 0.003 0.0071 0.0068
Echinococcus granulosus GPCR family 2 0.0069 0.027 0.027
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0023 0.0034 0.0046
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0071
Echinococcus granulosus calpain A 0.0142 0.0651 0.0651
Mycobacterium ulcerans putative regultory protein 0.003 0.0071 0.0341
Echinococcus granulosus geminin 0.0173 0.0811 0.0811
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0087 0.0118
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0031 0.0031
Brugia malayi hypothetical protein 0.0036 0.0104 0.0104
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0035 0.0035
Brugia malayi Animal haem peroxidase family protein 0.013 0.0588 0.0588
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0217 0.1039 0.1039
Onchocerca volvulus 0.1016 0.5172 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0036 0.0104 0.0141
Echinococcus multilocularis GPCR, family 2 0.0069 0.027 0.027
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.013 0.0127
Schistosoma mansoni heat shock protein 0.003 0.0071 0.0097
Mycobacterium tuberculosis Conserved protein 0.0036 0.0099 0.0511
Echinococcus multilocularis microtubule associated protein 2 0.1437 0.735 0.735
Trypanosoma cruzi kinesin, putative 0.004 0.0123 0.012
Brugia malayi NADH dehydrogenase subunit 1 0.0037 0.0105 0.0105
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.005 0.0218
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0294 0.0291
Schistosoma mansoni alpha-glucosidase 0.0504 0.2522 0.3431
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.005 0.0218
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0152 0.0701 0.0698
Brugia malayi Nuclear hormone receptor E75 0.0057 0.0212 0.0212
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0099 0.0161
Schistosoma mansoni RAR-like nuclear receptor 0.0122 0.0544 0.074
Giardia lamblia hypothetical protein 0.0152 0.0701 0.4027
Loa Loa (eye worm) RNA binding protein 0.0132 0.0599 0.0599
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0037 0.0034
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0012 0.0009
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0017 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0169 0.0169
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0722 0.3651 0.3649
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Schistosoma mansoni cellular tumor antigen P53 0.0079 0.0325 0.0442
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0037 0.0162
Plasmodium vivax calpain, putative 0.004 0.0123 0.075
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0599 0.0816
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0011 0.0015
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.0054 0.0031
Loa Loa (eye worm) hypothetical protein 0.0949 0.4825 0.4825
Schistosoma mansoni alpha glucosidase 0.013 0.0587 0.0799
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0152 0.0701 0.0954
Loa Loa (eye worm) hypothetical protein 0.0036 0.0099 0.0099
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.1047 0.5334 1
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0099 0.0161
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0053 0.0053
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0152 0.0701 0.0701
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0243 0.033
Loa Loa (eye worm) serotonin transporter b 0.0109 0.0482 0.0482
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0123 0.0549 0.0549
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0057 0.0208 0.0208
Schistosoma mansoni zinc finger protein 0.0017 0.0003 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0264 0.1446
Trypanosoma brucei DNA topoisomerase II beta, putative 0.003 0.0071 0.0068
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0135 0.0615 0.0615
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0257 0.035
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0033 0.0033
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0154 0.0942
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Echinococcus granulosus mitogen activated protein kinase 0.0068 0.0266 0.0266
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0294 0.0291
Onchocerca volvulus 0.0043 0.0136 0.0242
Echinococcus granulosus importin subunit beta 1 0.0032 0.0081 0.0081
Schistosoma mansoni retinoic acid receptor RXR 0.0122 0.0544 0.074
Echinococcus multilocularis calpain family protein 1, d 0.0095 0.0407 0.0407
Trypanosoma brucei calpain-like protein, putative 0.004 0.0123 0.012
Entamoeba histolytica Ran family GTPase 0.0024 0.0037 0.0361
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0012 0.0009
Onchocerca volvulus 0.002 0.0016 0.001
Leishmania major developmentally regulated phosphoprotein-like protein 0.0543 0.2724 0.2723
Trichomonas vaginalis conserved hypothetical protein 0.0895 0.4548 0.8523
Brugia malayi diacylglycerol kinase 0.0023 0.0034 0.0034
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0049 0.0046
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0037 0.0073
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0104
Onchocerca volvulus 0.0338 0.1667 0.3208
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0294 0.4869
Loa Loa (eye worm) hypothetical protein 0.0292 0.1424 0.1424
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0044 0.0143 0.0195
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0154 0.0263
Schistosoma mansoni ferritin 0.0027 0.0054 0.0074
Loa Loa (eye worm) hypothetical protein 0.0069 0.027 0.027
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0019 0.0011 0.0011
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0016 0.0016
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.0071 0.0068
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0285 0.0285
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0057 0.0212 0.0212
Echinococcus granulosus Nuclear hormone receptor HR96 0.0057 0.0212 0.0212
Onchocerca volvulus 0.0079 0.0325 0.0608
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.003 0.0071 0.0341
Mycobacterium ulcerans formate hydrogenlyase HycD 0.0037 0.0105 0.0533
Mycobacterium tuberculosis Conserved protein 0.0036 0.0099 0.0511
Onchocerca volvulus 0.0029 0.0066 0.0107
Giardia lamblia Kinase, CMGC MAPK 0.0068 0.0266 0.1389
Brugia malayi protein kinase C II. 0.0033 0.0087 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0122 0.0544 0.0544
Toxoplasma gondii exonuclease III APE 0.0061 0.0231 0.0501
Leishmania major cAMP-specific phosphodiesterase, putative 0.0152 0.0701 0.07
Echinococcus granulosus intermediate filament protein 0.0117 0.0522 0.0522
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.003 0.0071 0.035
Entamoeba histolytica calpain large subunit domain III containing protein 0.004 0.0123 0.1875
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0068 0.0267 0.0265
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0095 0.0407 0.0407
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0264 0.1446
Trichomonas vaginalis endoplasmin, putative 0.003 0.0071 0.0108
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase subunit H 0.0136 0.062 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.1047 0.5334 0.5333
Leishmania major C-8 sterol isomerase-like protein 0.0292 0.1424 0.1423
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Loa Loa (eye worm) hypothetical protein 0.0543 0.2724 0.2724
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0099 0.06
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0011 0.0046
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Trichomonas vaginalis DNA topoisomerase II, putative 0.003 0.0071 0.0108
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.003 0.0071 0.0149
Trypanosoma brucei heat shock protein, putative 0.003 0.0071 0.0068
Loa Loa (eye worm) hypothetical protein 0.0043 0.0136 0.0136
Brugia malayi Muscleblind-like protein 0.0949 0.4825 0.4825
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Echinococcus granulosus lysosomal alpha glucosidase 0.0585 0.2943 0.2943
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0105 0.0456 0.0621
Echinococcus granulosus myotubularin protein 13 0.0023 0.0034 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0587 0.1077
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0122 0.0544 0.0544
Loa Loa (eye worm) nuclear hormone receptor 0.0057 0.0212 0.0212
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.004 0.0123 0.012
Brugia malayi nuclear hormone receptor family member odr-7 0.0057 0.0212 0.0212
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0152 0.0701 0.0701
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0695 0.0695
Entamoeba histolytica hypothetical protein 0.0072 0.0289 0.478
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0109 0.0482 0.0482
Brugia malayi sulfakinin receptor protein 0.0081 0.0333 0.0333
Leishmania major cathepsin L-like protease 0.0075 0.0301 0.03
Echinococcus multilocularis geminin 0.0173 0.0811 0.0811
Trichomonas vaginalis conserved hypothetical protein 0.1047 0.5334 1
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0355 0.1754 1
Echinococcus multilocularis muscleblind protein 1 0.0949 0.4825 0.4825
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0048 0.0165 0.0285
Plasmodium falciparum endoplasmin, putative 0.003 0.0071 0.0379
Mycobacterium tuberculosis Probable sensor protein KdpD 0.003 0.0071 0.035
Brugia malayi hypothetical protein 0.013 0.0588 0.0588
Echinococcus granulosus zinc finger protein 0.0027 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0417 0.2074 0.2822
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0152 0.0701 0.0698
Loa Loa (eye worm) raf kinase 0.0654 0.3301 0.3301
Schistosoma mansoni pyruvate dehydrogenase 0.0513 0.2568 0.3494
Schistosoma mansoni c4b-binding protein beta chain 0.0043 0.0136 0.0185
Loa Loa (eye worm) hypothetical protein 0.0043 0.0136 0.0136
Schistosoma mansoni diacylglycerol kinase theta 0.0023 0.0034 0.0046
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0016 0.0022
Schistosoma mansoni unc-13 (munc13) 0.0023 0.0034 0.0046
Echinococcus granulosus heat shock protein 0.003 0.0071 0.0071
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0154 0.033
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0099 0.0511
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0068 0.0266 0.0265
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Schistosoma mansoni acetylcholinesterase 0.0036 0.0104 0.0141
Entamoeba histolytica DNA topoisomerase II, putative 0.003 0.0071 0.0963
Loa Loa (eye worm) hypothetical protein 0.0095 0.0407 0.0407
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0099 0.0503
Brugia malayi AMP-binding enzyme family protein 0.0026 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0325 0.1598 0.2978
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.005 0.0218
Brugia malayi MAP kinase sur-1 0.0068 0.0266 0.0266
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0064 0.0247 0.0247
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.013 0.0277
Onchocerca volvulus 0.0117 0.0522 0.099
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0019 0.0014 0.0011
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0543 0.2724 0.2722
Onchocerca volvulus Cathepsin L homolog 0.002 0.0016 0.001
Brugia malayi nuclear receptor RXR 0.0064 0.0247 0.0247
Schistosoma mansoni hypothetical protein 0.0022 0.0031 0.0043
Onchocerca volvulus 0.0037 0.0105 0.0181
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0152 0.0701 0.1291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0122 0.0544 0.0544
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.009 0.0189
Loa Loa (eye worm) hypothetical protein 0.0064 0.0247 0.0247
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0011 0.0011
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0036 0.0104 0.0104
Trichomonas vaginalis receptor histidine kinase, putative 0.003 0.0071 0.0108
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0122 0.0544 0.0544
Brugia malayi ecdysteroid receptor 0.028 0.1362 0.1362
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0023 0.0034 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0266 0.0474
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0477 0.2384 0.4455
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.013 0.0587 0.1283
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0064 0.0247 0.0336
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.1047 0.5334 0.7258
Schistosoma mansoni inositol monophosphatase 0.0041 0.013 0.0176
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0071 0.0068
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0036 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0016 0.0005
Brugia malayi DNA topoisomerase II, alpha isozyme 0.003 0.0071 0.0071
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0142 0.0651 0.0885
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0043 0.0136 0.0136
Echinococcus granulosus Nuclear hormone receptor HR96 0.0057 0.0212 0.0212
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0122 0.0544 0.0544
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0023 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0122 0.0544 0.0544
Echinococcus granulosus protein kinase c eta type 0.0023 0.0034 0.0034
Brugia malayi hypothetical protein 0.0057 0.0212 0.0212
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0013 0.0013
Brugia malayi Raf kinase 0.0635 0.3199 0.3199
Schistosoma mansoni DNA topoisomerase II 0.003 0.0071 0.0097
Echinococcus multilocularis lamin 0.0117 0.0522 0.0522
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.003 0.0071 0.0071
Plasmodium vivax heat shock protein 86, putative 0.003 0.0071 0.0423
Brugia malayi RNA, U transporter 1 0.0091 0.0386 0.0386
Onchocerca volvulus 0.013 0.0588 0.1117
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0599 0.0816
Toxoplasma gondii diacylglycerol kinase, putative 0.0023 0.0034 0.0066
Echinococcus multilocularis myotubularin protein 13 0.0023 0.0034 0.0034
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0152 0.0701 0.0698
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0016 0.0016
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.013 0.1329
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0294 0.0294
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0049 0.0067
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.0301 0.0298
Echinococcus multilocularis mitogen activated protein kinase 11 0.1949 1 1
Loa Loa (eye worm) hypothetical protein 0.0216 0.1033 0.1033
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Onchocerca volvulus Cathepsin L homolog 0.002 0.0016 0.001
Loa Loa (eye worm) hypothetical protein 0.0079 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0289 0.0393
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0031 0.0031
Schistosoma mansoni nuclear receptor 0.0057 0.0212 0.0288
Onchocerca volvulus 0.0036 0.0104 0.018
Schistosoma mansoni protein kinase C mu 0.0023 0.0034 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.005 0.0218
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.003 0.0071 0.0108
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0036 0.0104 0.0537
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.004 0.0123 0.012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0104
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0037 0.0208
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Schistosoma mansoni serine/threonine protein kinase 0.0463 0.2312 0.3146
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0023 0.0034 0.0034
Onchocerca volvulus 0.0095 0.0407 0.0767
Onchocerca volvulus Chorion peroxidase homolog 0.013 0.0588 0.1117
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.0011 0.0011
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0036 0.0099 0.0099
Schistosoma mansoni rab6-interacting 0.0022 0.0031 0.0043
Toxoplasma gondii rhoptry neck protein RON9 0.0043 0.0136 0.0291
Schistosoma mansoni ran 0.0024 0.0037 0.005
Brugia malayi nuclear hormone receptor 0.0057 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.013 0.0218
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0122 0.0544 0.0544
Loa Loa (eye worm) hypothetical protein 0.0117 0.0522 0.0522
Schistosoma mansoni neuroligin 3 (S09 family) 0.0036 0.0104 0.0141
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0068 0.0266 0.0263
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0016 0.0075
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0342 0.1686 0.1686
Mycobacterium ulcerans hypothetical protein 0.0036 0.0099 0.0503
Brugia malayi nuclear hormone receptor family member nhr-6 0.0057 0.0212 0.0212
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.013 0.0587 1
Entamoeba histolytica hypothetical protein 0.0072 0.0289 0.478
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.0016
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Schistosoma mansoni bromodomain containing protein 0.0076 0.0306 0.0416
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.019 0.0897 0.1966
Brugia malayi hypothetical protein 0.0064 0.0247 0.0247
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.066 0.066
Echinococcus granulosus dnaJ subfamily B 0.0417 0.2074 0.2074
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Schistosoma mansoni hypothetical protein 0.0342 0.1683 0.229
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0122 0.0544 0.0544
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.013 0.0128
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1949 1 1
Plasmodium vivax vivapain-2 0.002 0.0016 0.0079
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0292 0.1424 0.1422
Mycobacterium tuberculosis Conserved protein 0.003 0.0071 0.035
Schistosoma mansoni importin beta-1 0.0032 0.0081 0.011
Plasmodium falciparum GAF domain-related protein, putative 0.0325 0.1598 1
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0152 0.0701 0.0701
Loa Loa (eye worm) animal heme peroxidase 0.013 0.0588 0.0588
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0107 0.0556
Echinococcus multilocularis lamin dm0 0.0117 0.0522 0.0522
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Onchocerca volvulus 0.013 0.0588 0.1117
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0264 0.0572
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0012 0.0012
Loa Loa (eye worm) calpain 0.004 0.0123 0.0123
Leishmania major hypothetical protein, conserved 0.003 0.0071 0.007
Onchocerca volvulus 0.002 0.0016 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1047 0.5334 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1799 0.9226 0.9226
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Loa Loa (eye worm) animal heme peroxidase 0.013 0.0588 0.0588
Trypanosoma brucei DNA topoisomerase ii 0.003 0.0071 0.0068
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0031 0.0031
Mycobacterium ulcerans lipase LipD 0.0036 0.0099 0.0503
Trypanosoma brucei C-8 sterol isomerase, putative 0.0292 0.1424 0.1422
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0071
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0057 0.0212 0.0288
Leishmania major cytochrome p450-like protein 0.0019 0.0012 0.001
Brugia malayi hypothetical protein 0.0081 0.0333 0.0333
Schistosoma mansoni microtubule-associated protein tau 0.1437 0.735 1
Brugia malayi beta-lactamase 0.0036 0.0099 0.0099
Echinococcus multilocularis calpain 0.004 0.0123 0.0123
Mycobacterium ulcerans hypothetical protein 0.0049 0.0167 0.0894
Schistosoma mansoni thyroid hormone receptor 0.0261 0.1265 0.1721
Brugia malayi hypothetical protein 0.0043 0.0136 0.0136
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.1047 0.5334 0.5333
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.003 0.0071 0.0341
Loa Loa (eye worm) fibroinase 0.002 0.0016 0.0016
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0064 0.0087
Schistosoma mansoni lozenge 0.0127 0.0574 0.0781
Schistosoma mansoni vav2 0.0023 0.0034 0.0046
Brugia malayi Pre-SET motif family protein 0.0232 0.1114 0.1114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0069 0.027 0.027
Brugia malayi orphan nuclear receptor NR2E1 0.0057 0.0212 0.0212
Echinococcus multilocularis neutral alpha glucosidase AB 0.013 0.0587 0.0587
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.013 0.0218
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0099 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.009 0.0122
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0011 0.0015
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0142 0.0651 0.0651
Plasmodium vivax DNA topoisomerase II, putative 0.003 0.0071 0.0423
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0019 0.0011 0.0011
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0152 0.0701 0.0698
Echinococcus granulosus cpg binding protein 0.0033 0.0086 0.0086
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0068 0.0266 0.0266
Leishmania major hypothetical protein, conserved 0.0152 0.0701 0.07
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.019 0.0897 0.0894
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.003 0.0071 0.035
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0122 0.0544 0.074
Trypanosoma cruzi DNA topoisomerase II, putative 0.003 0.0071 0.0068
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0057 0.0212 0.0212
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0016 0.0032
Schistosoma mansoni hypothetical protein 0.0069 0.027 0.0368
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0122 0.0544 0.0544
Echinococcus multilocularis zinc finger protein 0.0027 0.0055 0.0055
Trichomonas vaginalis maltase-glucoamylase, putative 0.0048 0.0165 0.0285
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0031 0.0031
Trypanosoma brucei heat shock protein, putative 0.003 0.0071 0.0068
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.013 0.013
Brugia malayi hypothetical protein 0.0043 0.0136 0.0136
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0071 0.0068
Trypanosoma cruzi calpain cysteine peptidase, putative 0.004 0.0123 0.012
Brugia malayi Calcitonin receptor-like protein seb-1 0.0217 0.1039 0.1039
Schistosoma mansoni cpg binding protein 0.0029 0.0066 0.009
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0152 0.0701 0.0954
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.005 0.0227
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0071 0.0068
Mycobacterium ulcerans hypothetical protein 0.0026 0.005 0.0218
Schistosoma mansoni diacylglycerol kinase theta 0.0023 0.0034 0.0046
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Echinococcus granulosus c-Jun N-terminal kinases 0.0463 0.2312 0.2312
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.003 0.0071 0.0071
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0117 0.0522 0.0522
Brugia malayi nuclear receptor RXR 0.0057 0.0212 0.0212
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0154 0.0263
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0056 0.0207 0.0448
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Brugia malayi calpain 7 0.004 0.0123 0.0123
Brugia malayi hypothetical protein 0.0025 0.0044 0.0044
Schistosoma mansoni atypical protein kinase C 0.0033 0.0087 0.0118
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0142 0.0651 0.0885
Echinococcus multilocularis FTZ F1 alpha 0.0122 0.0544 0.0544
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Schistosoma mansoni calpain-7 (C02 family) 0.004 0.0123 0.0168
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0285 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0895 0.4548 0.8523
Schistosoma mansoni hypothetical protein 0.0173 0.0811 0.1103
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Onchocerca volvulus 0.0057 0.0212 0.0389
Loa Loa (eye worm) hypothetical protein 0.1016 0.5172 0.5172
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0049 0.0067
Loa Loa (eye worm) intermediate filament protein 0.0117 0.0522 0.0522
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0016 0.0005
Plasmodium vivax DNA gyrase subunit B, putative 0.003 0.0071 0.0423
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0048 0.0165 0.0162
Echinococcus granulosus calpain 7 C02 family 0.004 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0325 0.1598 0.1598
Schistosoma mansoni pyruvate dehydrogenase 0.0513 0.2568 0.3494
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Echinococcus granulosus thymidylate synthase 0.004 0.0123 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0122 0.0544 0.0544
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0105 0.0456 0.0456
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0033 0.0087 0.0087
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0216 0.1033 0.1405
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0105 0.0456 0.0456
Brugia malayi RNA binding protein 0.0132 0.0599 0.0599
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Echinococcus multilocularis calcium activated potassium channel 0.0017 0.0002 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.0212 0.0212
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0105 0.0456 0.0456
Schistosoma mansoni nuclear hormone receptor 0.0057 0.0212 0.0288
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0033 0.0087 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0122 0.0544 0.0544
Onchocerca volvulus 0.0036 0.0099 0.0171
Leishmania major glycosyl hydrolase-like protein 0.0048 0.0165 0.0164
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0264 0.0359
Schistosoma mansoni ap endonuclease 0.0061 0.0231 0.0315
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.003 0.0071 0.035
Plasmodium vivax importin-beta 2, putative 0.0032 0.0081 0.0482
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Plasmodium vivax phosphodiesterase gamma, putative 0.0152 0.0701 0.4373
Brugia malayi hypothetical protein 0.0019 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0122 0.0544 0.0544
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0061 0.0231 0.1268
Mycobacterium ulcerans DNA gyrase subunit B 0.003 0.0071 0.0341
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0122 0.0544 0.0544
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0134 0.0134
Schistosoma mansoni Mername-AA248 (C02 family) 0.004 0.0123 0.0168
Brugia malayi RhoGAP domain containing protein 0.0023 0.0034 0.0034
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0105 0.0456 0.0456
Echinococcus multilocularis calpain A 0.0142 0.0651 0.0651
Echinococcus multilocularis musashi 0.0117 0.0522 0.0522
Echinococcus granulosus acetylcholinesterase 0.0216 0.1033 0.1033
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.003 0.0071 0.0068
Leishmania major hypothetical protein, conserved 0.0036 0.0099 0.0098
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0033 0.0087 0.0087
Brugia malayi kinase, mitochondrial precursor 0.0543 0.2724 0.2724
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0152 0.0701 0.0954
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.013 0.0127
Trypanosoma brucei glucosidase, putative 0.013 0.0587 0.0584
Mycobacterium tuberculosis Carboxylesterase LipT 0.0036 0.0104 0.0537
Schistosoma mansoni apoferritin-2 0.0027 0.0054 0.0074
Plasmodium falciparum phosphodiesterase gamma, putative 0.0152 0.0701 0.4347
Echinococcus granulosus cathepsin l1 0.002 0.0016 0.0016
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0294 0.0293
Mycobacterium leprae Probable lipase LipE 0.0036 0.0099 0.032
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0016 0.0016
Schistosoma mansoni ferritin 0.0027 0.0054 0.0074
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0069 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0079 0.0325 0.0325
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1949 1 1
Brugia malayi hypothetical protein 0.0022 0.0031 0.0031
Echinococcus granulosus nuclear receptor nhr 48 0.0057 0.0212 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0122 0.0544 0.0544
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.0011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.004 0.0123 0.0122
Leishmania major cathepsin L-like protease 0.002 0.0016 0.0015
Echinococcus granulosus raf serine:threonine protein kinase 0.0658 0.3317 0.3317
Onchocerca volvulus Huntingtin homolog 0.0296 0.1448 0.2784
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.003 0.0071 0.0379
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0036 0.0104 0.0537
Loa Loa (eye worm) cysteine protease 0.002 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Echinococcus multilocularis unc 13 (munc13) 0.0023 0.0034 0.0034
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0063 0.0241 0.0241
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.013 0.0677
Brugia malayi Importin beta-1 subunit 0.0032 0.0081 0.0081
Loa Loa (eye worm) solute carrier family 6 member 4 0.0109 0.0482 0.0482
Toxoplasma gondii GAF domain-containing protein 0.0325 0.1598 0.3508
Onchocerca volvulus 0.0023 0.0034 0.0044
Trichomonas vaginalis set domain proteins, putative 0.0264 0.1279 0.2378
Brugia malayi GCC2 and GCC3 family protein 0.0049 0.0169 0.0169
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Schistosoma mansoni polycystin 1-related 0.0022 0.0031 0.0043
Echinococcus granulosus calpain 0.004 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0136 0.062 0.0843
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Trypanosoma brucei antigen, putative 0.004 0.0123 0.012
Toxoplasma gondii hypothetical protein 0.0325 0.1598 0.3508
Loa Loa (eye worm) hypothetical protein 0.0477 0.2384 0.2384
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0057 0.0212 0.0212
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0012 0.0012
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0053 0.0053
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0165 0.0285
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0011
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0068 0.0266 0.0263
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0053 0.0072
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0152 0.0701 0.0698
Plasmodium falciparum DNA topoisomerase 2 0.003 0.0071 0.0379
Onchocerca volvulus 0.0043 0.0136 0.0242
Echinococcus granulosus tumor protein p63 0.0542 0.2717 0.2717
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0152 0.0701 0.1291
Schistosoma mansoni rac gtpase activating protein 0.0023 0.0034 0.0046
Brugia malayi hypothetical protein 0.0043 0.0136 0.0136
Echinococcus granulosus thyroid hormone receptor alpha 0.0057 0.0212 0.0212
Onchocerca volvulus 0.002 0.0016 0.001
Schistosoma mansoni rab6-interacting 0.0022 0.0031 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Loa Loa (eye worm) hypothetical protein 0.0152 0.0701 0.0701
Schistosoma mansoni hypothetical protein 0.0023 0.0034 0.0046
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Onchocerca volvulus 0.002 0.0016 0.001
Mycobacterium ulcerans carboxylesterase, LipT 0.0036 0.0104 0.0528
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0069 0.027 0.027
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Schistosoma mansoni calpain-7 (C02 family) 0.004 0.0123 0.0168
Trypanosoma brucei calpain-like protein, putative 0.004 0.0123 0.012
Schistosoma mansoni inositol monophosphatase 0.0041 0.013 0.0176
Onchocerca volvulus Protein ultraspiracle homolog 0.0122 0.0544 0.1033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0011
Schistosoma mansoni protein kinase C mu 0.0033 0.0087 0.0118
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.1047 0.5334 1
Trypanosoma brucei kinesin, putative 0.004 0.0123 0.012
Brugia malayi calpain family protein 1 0.0135 0.0615 0.0615
Onchocerca volvulus 0.0036 0.0104 0.018
Giardia lamblia Pms1-like protein 0.003 0.0071 0.0208
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0105 0.0456 0.0456
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0722 0.3651 0.6837
Schistosoma mansoni coup transcription factor 0.0122 0.0544 0.074
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.004 0.0123 0.0122
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.4347
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.0054 0.0246
Trypanosoma cruzi major cysteine proteinase, putative 0.0059 0.0218 0.0216
Schistosoma mansoni hypothetical protein 0.0069 0.027 0.0368
Echinococcus granulosus mitogen activated protein kinase 3 0.0068 0.0266 0.0266
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0063 0.024 0.024
Echinococcus granulosus N chimaerin 0.0023 0.0034 0.0034
Plasmodium falciparum cGMP-dependent protein kinase 0.0059 0.022 0.1319
Schistosoma mansoni peroxidasin 0.013 0.0588 0.0799
Schistosoma mansoni nuclear receptor nhr-48 0.0057 0.0212 0.0288
Brugia malayi hypothetical protein 0.1016 0.5172 0.5172
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0056 0.0207 0.1277
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0099 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0122 0.0544 0.0544
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.003 0.0071 0.035
Loa Loa (eye worm) hypothetical protein 0.0032 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0054 0.0197 0.0197
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0152 0.0701 0.0954
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0099 0.0097
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0048 0.0165 0.2611
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.013 0.013
Onchocerca volvulus 0.0036 0.0099 0.0171
Trypanosoma brucei calpain-like protein, putative 0.004 0.0123 0.012
Leishmania major GTP-binding protein, putative 0.0024 0.0037 0.0036
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0037 0.0034
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.003 0.0071 0.0139
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0033 0.0087 0.0087
Trichomonas vaginalis ferritin, putative 0.0027 0.0054 0.0077
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0342 0.1686 0.1686
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0017 0.0004 0.0001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0011 0.0015
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0342 0.1686 0.1686
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0064 0.0247 0.0247
Schistosoma mansoni cpg binding protein 0.0033 0.0086 0.0117
Loa Loa (eye worm) hypothetical protein 0.0043 0.0136 0.0136
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0081 0.0078
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0059 0.022 0.022
Brugia malayi calpain 5 0.004 0.0123 0.0123
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.1047 0.5334 1
Brugia malayi Bromodomain containing protein 0.0046 0.0154 0.0154
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.013 0.0587 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0109 0.0482 0.0655
Loa Loa (eye worm) calpain family protein 1 0.0135 0.0615 0.0615
Loa Loa (eye worm) carboxylesterase 0.0036 0.0104 0.0104
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.1291
Echinococcus multilocularis thymidylate synthase 0.004 0.0123 0.0123
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0134 0.0134
Trypanosoma cruzi hypothetical protein, conserved 0.0152 0.0701 0.0698
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0037 0.0037
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.005 0.0587
Trypanosoma cruzi Heat shock protein 83, putative 0.003 0.0071 0.0068
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.0054 0.0246
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0056 0.0207 0.1236
Giardia lamblia Hypothetical protein 0.0152 0.0701 0.4027
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.004 0.0123 0.0645
Schistosoma mansoni calpain (C02 family) 0.004 0.0123 0.0168
Brugia malayi Cathepsin L-like precursor 0.002 0.0016 0.0016
Echinococcus granulosus protein kinase c epsilon type 0.0033 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0152 0.0701 0.1291
Schistosoma mansoni BC026374 protein (S09 family) 0.0036 0.0104 0.0141
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0294 0.0291
Brugia malayi Carboxylesterase family protein 0.0036 0.0104 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Schistosoma mansoni ferritin 0.0027 0.0054 0.0074
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0232 0.1114 0.1114
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0122 0.0544 0.074
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0535 0.2682 0.365
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.1093 0.6208
Loa Loa (eye worm) hypothetical protein 0.0043 0.0136 0.0136
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0061 0.0231 0.0231
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0152 0.0701 0.0701
Brugia malayi Nuclear hormone receptor-like 1 0.0064 0.0247 0.0247
Echinococcus granulosus para nitrobenzyl esterase 0.0036 0.0104 0.0104
Onchocerca volvulus Cathepsin F homolog 0.002 0.0016 0.001
Schistosoma mansoni ap endonuclease 0.0061 0.0231 0.0315
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0064 0.0247 0.0247
Brugia malayi hypothetical protein 0.0043 0.0136 0.0136
Echinococcus multilocularis para nitrobenzyl esterase 0.0036 0.0104 0.0104
Echinococcus granulosus lamin dm0 0.0117 0.0522 0.0522
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0123 0.012
Echinococcus multilocularis serotonin transporter 0.0109 0.0482 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0895 0.4548 0.8523
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.004 0.0123 0.0167
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0152 0.0701 0.0954
Schistosoma mansoni cpg binding protein 0.0033 0.0086 0.0117
Loa Loa (eye worm) hypothetical protein 0.0296 0.1448 0.1448
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0059 0.022 0.022
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0121 0.0121
Brugia malayi MH2 domain containing protein 0.0241 0.1164 0.1164
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.0301 0.0298
Trypanosoma cruzi cruzipain precursor, putative 0.0075 0.0301 0.0298
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0087 0.0118
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.004 0.0123 0.012
Echinococcus multilocularis cpg binding protein 0.0033 0.0086 0.0086
Brugia malayi Glycosyl hydrolases family 31 protein 0.0585 0.2943 0.2943
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0023 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0016 0.0005
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0122 0.0544 0.0544
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0104
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.003 0.0071 0.0068
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0099 0.0161
Brugia malayi Latrophilin receptor protein 2 0.0069 0.027 0.027
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0599 0.0816
Schistosoma mansoni microsomal glutathione s-transferase 0.0123 0.0549 0.0747
Echinococcus granulosus microsomal glutathione S transferase 3 0.0123 0.0549 0.0549
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0016 0.0005
Schistosoma mansoni intermediate filament proteins 0.0117 0.0522 0.071
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0068 0.0266 0.0577
Mycobacterium tuberculosis Possible formate hydrogenlyase HycD (FHL) 0.0037 0.0105 0.0542
Entamoeba histolytica hypothetical protein 0.0072 0.0289 0.478
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.1291
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.022 0.03
Loa Loa (eye worm) hypothetical protein 0.0064 0.0247 0.0247
Echinococcus multilocularis RUN 0.0022 0.0031 0.0031
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0099 0.0099
Onchocerca volvulus 0.0034 0.009 0.0152
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0057 0.0212 0.0212
Echinococcus multilocularis expressed protein 0.0027 0.0054 0.0054
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.003 0.0071 0.035
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.009 0.009
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0585 0.2943 0.2943
Echinococcus multilocularis mitogen activated protein kinase 3 0.0068 0.0266 0.0266
Plasmodium vivax vivapain-2 0.002 0.0016 0.0079
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Onchocerca volvulus 0.0264 0.128 0.2459
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.019 0.09 0.09
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0036 0.0104 0.0141
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0068 0.0266 0.0263
Loa Loa (eye worm) steroid hormone receptor 0.0122 0.0544 0.0544
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.003 0.0071 0.0295
Brugia malayi NADH dehydrogenase subunit 1, identical 0.0037 0.0105 0.0105
Brugia malayi beta-lactamase family protein 0.0036 0.0099 0.0099
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0061 0.0231 0.0229
Schistosoma mansoni hypothetical protein 0.0072 0.0289 0.0393
Leishmania major DNA topoisomerase ii 0.003 0.0071 0.007
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.003 0.0071 0.0341
Echinococcus multilocularis heat shock protein 0.003 0.0071 0.0071
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0061 0.0231 0.0229
Schistosoma mansoni hypothetical protein 0.0148 0.0683 0.0929
Brugia malayi Carboxylesterase family protein 0.0036 0.0104 0.0104
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0266 0.0474
Toxoplasma gondii heat shock protein 90, putative 0.003 0.0071 0.0149
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Plasmodium falciparum ataxin-2 like protein, putative 0.0039 0.0114 0.065
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0587 0.1077
Loa Loa (eye worm) hypothetical protein 0.0122 0.0544 0.0544
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0105 0.0456 0.0621
Brugia malayi hypothetical protein 0.0057 0.0212 0.0212
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0016 0.0032
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0023 0.0034 0.0034
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.004 0.0123 0.012
Echinococcus multilocularis mitogen activated protein kinase 14 0.1949 1 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0016 0.0023
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0477 0.2384 0.3243
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0132 0.0599 0.0599
Plasmodium falciparum apical sushi protein 0.0043 0.0136 0.0788
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0158 0.0735 0.1608
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.003 0.0071 1
Brugia malayi Egg laying defective protein 4 0.0059 0.022 0.022
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.019 0.09 0.09
Brugia malayi nuclear receptor NHR-67 0.0057 0.0212 0.0212
Loa Loa (eye worm) inositol-1 0.0041 0.013 0.013
Echinococcus multilocularis acetylcholinesterase 0.0216 0.1033 0.1033
Loa Loa (eye worm) hypothetical protein 0.0048 0.0161 0.0161
Plasmodium vivax amine transporter, putative 0.0019 0.0011 0.0046
Schistosoma mansoni hypothetical protein 0.0173 0.0811 0.1103
Brugia malayi Protein kinase domain containing protein 0.0033 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0104
Schistosoma mansoni gliotactin 0.0036 0.0104 0.0141
Loa Loa (eye worm) hypothetical protein 0.0149 0.0686 0.0686
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.0016
Echinococcus multilocularis ferritin 0.0027 0.0054 0.0054
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.013 0.0218
Echinococcus granulosus RUN 0.0022 0.0031 0.0031
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0037 0.0037
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0127 0.0127
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0122 0.0544 0.074
Loa Loa (eye worm) endoplasmin 0.003 0.0071 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0087 0.0118
Mycobacterium ulcerans putative regulatory protein 0.0325 0.1598 0.9103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0016 0.0013
Brugia malayi hypothetical protein 0.0037 0.0105 0.0105
Trypanosoma cruzi cysteine peptidase, putative 0.0075 0.0301 0.0298
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0474 0.2366 0.2366
Mycobacterium tuberculosis Hypothetical protein 0.0019 0.0014 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0001 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0087 0.0118
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0068 0.0266 0.0263
Brugia malayi hypothetical protein 0.0043 0.0136 0.0136
Loa Loa (eye worm) transcription factor SMAD2 0.0241 0.1164 0.1164
Echinococcus multilocularis ecdysone induced protein 78C 0.0122 0.0544 0.0544
Brugia malayi RhoGEF domain containing protein 0.0023 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0104
Schistosoma mansoni hypothetical protein 0.0069 0.027 0.0368
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0011 0.0015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0217 0.1039 0.1039
Trypanosoma brucei heat shock protein 90, putative 0.003 0.0071 0.0068
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0165 0.0285
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0061 0.0231 0.1261
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0477 0.2384 0.2384
Loa Loa (eye worm) hypothetical protein 0.0081 0.0333 0.0333
Plasmodium vivax hypothetical protein, conserved 0.003 0.0071 0.0423
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Mycobacterium ulcerans thymidylate synthase 0.004 0.0123 0.0636
Echinococcus granulosus ecdysone induced protein 78C 0.0122 0.0544 0.0544
Echinococcus granulosus cGMP dependent protein kinase 1 0.0059 0.022 0.022
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0154 0.033
Loa Loa (eye worm) DR-78 0.0057 0.0212 0.0212
Schistosoma mansoni heat shock protein 0.003 0.0071 0.0097
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0152 0.0701 0.0701
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Schistosoma mansoni zinc finger protein 0.0027 0.0055 0.0074
Brugia malayi Bromodomain containing protein 0.0089 0.0373 0.0373
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.0054 0.0254
Schistosoma mansoni sodium-dependent amino acid transporter 0.0019 0.0011 0.0015
Echinococcus granulosus c4b binding protein beta chain 0.0043 0.0136 0.0136
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0152 0.0701 0.0954
Plasmodium vivax endoplasmin, putative 0.003 0.0071 0.0423
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Onchocerca volvulus 0.004 0.0123 0.0216
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0012 0.0012
Brugia malayi hypothetical protein 0.0072 0.0289 0.0289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0016
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Treponema pallidum exodeoxyribonuclease (exoA) 0.0061 0.0231 0.4141
Toxoplasma gondii ABC1 family protein 0.0036 0.0099 0.021
Entamoeba histolytica diacylglycerol kinase, putative 0.0023 0.0034 0.0304
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0017 0.0004 0.0001
Trichomonas vaginalis receptor histidine kinase, putative 0.003 0.0071 0.0108
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0264 0.1446
Schistosoma mansoni lamin 0.0117 0.0522 0.071
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Echinococcus multilocularis calpain 5 0.004 0.0123 0.0123
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0068 0.0266 0.0265
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0061 0.0231 0.023
Mycobacterium leprae Probable two component sensor kinase MprB 0.003 0.0071 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0016 0.0016
Onchocerca volvulus Peroxidase homolog 0.013 0.0588 0.1117
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0066 0.0257 0.0257
Echinococcus granulosus muscleblind protein 0.0949 0.4825 0.4825
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0011
Toxoplasma gondii LsmAD domain-containing protein 0.0039 0.0114 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0152 0.0701 0.1291
Trypanosoma brucei Heat shock protein 83, putative 0.003 0.0071 0.0068
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0031 0.0127
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0048 0.0165 0.0162
Brugia malayi nuclear receptor NHR-88 0.0057 0.0212 0.0212
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0016 0.0758
Loa Loa (eye worm) hypothetical protein 0.0122 0.0544 0.0544
Brugia malayi Variant SH3 domain containing protein 0.0023 0.0034 0.0034
Trypanosoma brucei cAMP-specific phosphodiesterase 0.1047 0.5334 0.5333
Brugia malayi pregnancy-associated plasma protein-A 0.0043 0.0136 0.0136
Onchocerca volvulus DNA topoisomerase 2 homolog 0.003 0.0071 0.0116
Brugia malayi thymidylate synthase 0.004 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0044 0.0143 0.0143
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0122 0.0544 0.074
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0099 0.0099
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.0054 0.0254
Trypanosoma brucei heat shock protein, putative 0.003 0.0071 0.0068
Trypanosoma cruzi PAB1-binding protein , putative 0.0039 0.0114 0.0111
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0057 0.0212 0.0212
Brugia malayi C1-like domain containing protein 0.0033 0.0087 0.0087
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.022 0.1053 0.231
Loa Loa (eye worm) hypothetical protein 0.0296 0.1448 0.1448
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0019 0.0011 0.0015
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Leishmania major mitochondrial DNA topoisomerase II 0.003 0.0071 0.007
Trypanosoma brucei hypothetical protein, conserved 0.0152 0.0701 0.0698
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0152 0.0701 0.0701
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0477 0.2384 0.2384
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0122 0.0544 0.0544
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0188 0.0255
Schistosoma mansoni survival motor neuron protein 0.0097 0.0415 0.0564
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0121 0.1845
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.003 0.0071 0.0108
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.4347
Onchocerca volvulus 0.0097 0.0415 0.0782
Brugia malayi cytoplasmic intermediate filament protein 0.0063 0.024 0.024
Brugia malayi Cytochrome P450 family protein 0.0041 0.0127 0.0127
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0044 0.0143 0.0195
Brugia malayi Carboxylesterase family protein 0.0036 0.0104 0.0104
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0122 0.0544 0.0544
Trichomonas vaginalis maltase-glucoamylase, putative 0.013 0.0587 0.1077
Schistosoma mansoni sodium/chloride dependent transporter 0.0109 0.0482 0.0655
Brugia malayi nuclear receptor NHR-88 0.0122 0.0544 0.0544
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0152 0.0701 0.1291
Loa Loa (eye worm) hypothetical protein 0.0152 0.0701 0.0701
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.003 0.0071 0.0341
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0373 0.1844 0.1844
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0292 0.1424 0.1424
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.019 0.09 0.09
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0139 0.0636 0.0636
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Brugia malayi Cytochrome P450 family protein 0.0019 0.0012 0.0012
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0543 0.2724 0.2724
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0152 0.0701 0.1291
Mycobacterium leprae conserved hypothetical protein 0.0325 0.1598 1
Onchocerca volvulus 0.0036 0.0104 0.018
Echinococcus granulosus peroxidasin 0.013 0.0588 0.0588
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0016 0.0005
Echinococcus multilocularis protein kinase c epsilon type 0.0033 0.0087 0.0087
Brugia malayi Inositol-1 0.0041 0.013 0.013
Schistosoma mansoni nuclear hormone receptor 0.0122 0.0544 0.074
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0066 0.0257 0.0257
Onchocerca volvulus 0.0037 0.0105 0.0181
Brugia malayi Cathepsin L-like precursor 0.002 0.0016 0.0016
Echinococcus multilocularis Diacylglycerol kinase theta 0.0023 0.0034 0.0034
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0122 0.0544 0.0544
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0152 0.0701 0.0701
Loa Loa (eye worm) hypothetical protein 0.0148 0.0683 0.0683
Trypanosoma brucei glycosyl hydrolase-like protein 0.0048 0.0165 0.0162
Schistosoma mansoni hypothetical protein 0.0139 0.0636 0.0865
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.005 0.0218
Plasmodium falciparum importin beta, putative 0.0032 0.0081 0.0438
Mycobacterium ulcerans two component sensor kinase MprB 0.003 0.0071 0.0341
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.004 0.0123 0.012
Brugia malayi nuclear hormone receptor 0.0122 0.0544 0.0544
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0241 0.0522
Schistosoma mansoni unc-13 (munc13) 0.0023 0.0034 0.0046
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0057 0.0208 0.0208
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.0698
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0266 0.0474
Brugia malayi Animal haem peroxidase family protein 0.013 0.0588 0.0588
Echinococcus granulosus DNA topoisomerase 2 alpha 0.003 0.0071 0.0071
Loa Loa (eye worm) acetylcholinesterase 1 0.0216 0.1033 0.1033
Echinococcus multilocularis neuroligin 0.0036 0.0104 0.0104
Loa Loa (eye worm) RasGEF domain-containing protein 0.0023 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0053 0.0187 0.0187
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0543 0.2724 0.2724
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.005 0.0587
Echinococcus granulosus BC026374 protein S09 family 0.0036 0.0104 0.0104
Plasmodium vivax SET domain protein, putative 0.0034 0.009 0.0539
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0031 0.0031
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.003 0.0071 0.0068
Brugia malayi Melibiase family protein 0.0044 0.0143 0.0143
Echinococcus multilocularis BC026374 protein (S09 family) 0.0036 0.0104 0.0104
Onchocerca volvulus 0.0109 0.0482 0.0912
Echinococcus granulosus heat shock protein 90 0.003 0.0071 0.0071
Brugia malayi Peroxidasin 0.013 0.0588 0.0588
Trichomonas vaginalis spcc417.12 protein, putative 0.0036 0.0104 0.0169
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Plasmodium falciparum DNA gyrase subunit B 0.003 0.0071 0.0379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Loa Loa (eye worm) TAR-binding protein 0.0132 0.0599 0.0599
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0355 0.1754 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Brugia malayi protein kinase C3,putative 0.0033 0.0087 0.0087
Trichomonas vaginalis esterase, putative 0.0036 0.0099 0.0161
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.0011
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0037 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0016 0.0005
Echinococcus granulosus NADH dehydrogenase subunit 1 0.0136 0.062 0.062
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0342 0.1686 0.1686
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0087 0.0118
Echinococcus granulosus lamin 0.0117 0.0522 0.0522
Echinococcus multilocularis hypothetical protein 0.004 0.0123 0.0123
Brugia malayi ecdysone receptor 0.0057 0.0212 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0122 0.0544 0.0544
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0477 0.2384 0.4455
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.013 0.0587 0.1077
Brugia malayi Glycosyl hydrolases family 31 protein 0.013 0.0587 0.0587
Trypanosoma brucei protein kinase, putative 0.0068 0.0266 0.0263
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.005 0.0218
Loa Loa (eye worm) hypothetical protein 0.0135 0.0615 0.0615
Echinococcus granulosus C type lectin domian containing protein 0.0043 0.0136 0.0136
Schistosoma mansoni lipoxygenase 0.0022 0.0031 0.0043
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0587 0.1077
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0031 0.0031
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.003 0.0071 0.0295
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0057 0.0212 0.0389
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0122 0.0544 0.0544
Brugia malayi Animal haem peroxidase family protein 0.013 0.0588 0.0588
Brugia malayi intermediate filament protein 0.0117 0.0522 0.0522
Onchocerca volvulus 0.013 0.0588 0.1117
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0122 0.0544 0.0544
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0121 0.0121
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0342 0.1683 0.1683
Echinococcus granulosus cGMP dependent protein kinase 1 0.0059 0.022 0.022
Entamoeba histolytica protein kinase, putative 0.0051 0.0176 0.2804
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.005 0.0049
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0121 0.0514
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0064 0.0247 0.0336
Loa Loa (eye worm) animal heme peroxidase 0.013 0.0588 0.0588
Leishmania major cathepsin L-like protease 0.0075 0.0301 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0658 0.3317 0.4514
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0019 0.0011 0.0015
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.005 0.0049
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0063 0.0241 0.0241
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0016 0.0005
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.4373
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Loa Loa (eye worm) blistered cuticle protein 3 0.013 0.0588 0.0588
Leishmania major alpha glucosidase II subunit, putative 0.013 0.0587 0.0586
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.013 0.0127
Trypanosoma cruzi hypothetical protein, conserved 0.013 0.0587 0.0584
Trichomonas vaginalis CMGC family protein kinase 0.0068 0.0266 0.0474
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0142 0.0651 0.0651
Echinococcus multilocularis protein kinase c eta type 0.0023 0.0034 0.0034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0122 0.0544 0.0544
Echinococcus granulosus tar DNA binding protein 0.0132 0.0599 0.0599
Echinococcus multilocularis Rac GTPase activating protein 1 0.0023 0.0034 0.0034
Echinococcus granulosus unc 13 munc13 0.0023 0.0034 0.0034
Echinococcus multilocularis C type lectin domian containing protein 0.0043 0.0136 0.0136
Echinococcus multilocularis acetylcholinesterase 0.0216 0.1033 0.1033
Brugia malayi RNA recognition motif domain containing protein 0.0132 0.0599 0.0599
Mycobacterium leprae Probable two-component sensor kinase 0.003 0.0071 0.0139
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0061 0.0231 0.3129
Echinococcus granulosus ferritin 0.0027 0.0054 0.0054
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0355 0.1754 1
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0152 0.0701 0.0701
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0099 0.0511
Onchocerca volvulus 0.002 0.0016 0.001
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.003 0.0071 0.0108
Schistosoma mansoni hypothetical protein 0.0097 0.0415 0.0564
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0122 0.0544 0.0544
Onchocerca volvulus 0.0023 0.0034 0.0044
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0031 0.0173
Trichomonas vaginalis sensor histidine kinase, putative 0.003 0.0071 0.0108
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0477 0.2384 0.4455
Leishmania major cathepsin L-like protease 0.002 0.0016 0.0015
Leishmania major protein kinase, putative 0.0017 0.0004 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0599 0.0816
Brugia malayi CXXC zinc finger family protein 0.0029 0.0066 0.0066
Brugia malayi Animal haem peroxidase family protein 0.013 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0011
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0081 0.0078
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0231 0.0409
Onchocerca volvulus 0.0043 0.0136 0.0242
Onchocerca volvulus 0.0117 0.0522 0.099
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0349 0.172 0.3776
Loa Loa (eye worm) hypothetical protein 0.0122 0.0544 0.0544
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0099 0.0161
Echinococcus multilocularis muscleblind protein 0.0949 0.4825 0.4825
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1949 1 1
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.003 0.0071 0.0108
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Brugia malayi latrophilin 2 splice variant baaae 0.0148 0.0683 0.0683
Trypanosoma brucei heat shock protein, putative 0.003 0.0071 0.0068
Echinococcus granulosus Rac GTPase activating protein 1 0.0023 0.0034 0.0034
Mycobacterium ulcerans two component regulator - sensor kinase 0.003 0.0071 0.0341
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.005 0.0587
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0016 0.0032
Brugia malayi Ras association domain family 1 isoform A 0.0023 0.0034 0.0034
Toxoplasma gondii melibiase subfamily protein 0.0066 0.0257 0.0557
Brugia malayi tailless protein 0.0057 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0122 0.0544 0.0544
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0013 0.0017
Echinococcus granulosus Protein kinase C brain isozyme 0.0033 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0152 0.0701 0.1534
Echinococcus granulosus calpain A 0.004 0.0123 0.0123
Echinococcus granulosus microtubule associated protein 2 0.1437 0.735 0.735
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0057 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0069 0.027 0.0368
Toxoplasma gondii rhoptry neck protein RON1 0.0043 0.0136 0.0291
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.1047 0.5334 1
Brugia malayi Cathepsin L-like precursor 0.002 0.0016 0.0016
Brugia malayi Protein kinase c protein 2 0.0033 0.0087 0.0087
Echinococcus multilocularis raf serine:threonine protein kinase 0.0658 0.3317 0.3317
Loa Loa (eye worm) MH2 domain-containing protein 0.0241 0.1164 0.1164
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0069 0.027 0.027
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.005 0.0227
Toxoplasma gondii hypothetical protein 0.0019 0.0011 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0057 0.0212 0.0288
Echinococcus multilocularis tar DNA binding protein 0.0132 0.0599 0.0599
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0019 0.0011 0.0011
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.1047 0.5334 0.5333
Brugia malayi conserved hypotetical protein 0.0057 0.0212 0.0212
Brugia malayi Cathepsin L-like precursor 0.002 0.0016 0.0016
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.008 0.008
Loa Loa (eye worm) ctsf protein 0.002 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Entamoeba histolytica hypothetical protein 0.0072 0.0289 0.478
Schistosoma mansoni peroxidasin 0.013 0.0588 0.0799
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0188 0.0255
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0342 0.1686 0.2294
Entamoeba histolytica hypothetical protein 0.0026 0.0049 0.0578
Brugia malayi Sushi domain 0.0043 0.0136 0.0136
Echinococcus multilocularis dnaJ subfamily B 0.0417 0.2074 0.2074
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0152 0.0701 0.4347
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Echinococcus multilocularis tumor protein p63 0.0542 0.2717 0.2717
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0165 0.0285
Echinococcus multilocularis survival motor neuron protein 1 0.0474 0.2366 0.2366
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0152 0.0701 0.0954
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0695 0.0945
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.028 0.1362 0.1362
Brugia malayi AMP-binding enzyme family protein 0.0026 0.005 0.005
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0463 0.2312 0.2312
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.004 0.0123 0.012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0075 0.0301 0.0298
Echinococcus granulosus calpain 5 0.004 0.0123 0.0123
Brugia malayi TAR-binding protein 0.0132 0.0599 0.0599
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.019 0.0897 0.0894
Brugia malayi Nuclear hormone receptor-like 1 0.0064 0.0247 0.0247
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0152 0.0701 0.0701
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0165 0.0285
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.019 0.0897 0.0896
Brugia malayi calpain family protein 1 0.0135 0.0615 0.0615
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0121 0.0696
Loa Loa (eye worm) hypothetical protein 0.0036 0.0099 0.0099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0122 0.0544 0.0544
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.022 0.03
Loa Loa (eye worm) hypothetical protein 0.0109 0.0482 0.0482
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.004 0.0123 0.012
Loa Loa (eye worm) carboxylesterase 0.0036 0.0104 0.0104
Loa Loa (eye worm) calpain family protein 1 0.0095 0.0407 0.0407
Schistosoma mansoni lipoxygenase 0.0063 0.0241 0.0328
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0264 0.0359
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.003 0.0071 0.0149
Echinococcus multilocularis calpain 7 (C02 family) 0.004 0.0123 0.0123
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0016 0.0016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0099 0.0135
Trypanosoma cruzi hypothetical protein, conserved 0.0152 0.0701 0.0698
Loa Loa (eye worm) hypothetical protein 0.1016 0.5172 0.5172
Trypanosoma brucei developmentally regulated phosphoprotein 0.0543 0.2724 0.2722
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0099 0.0511
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0016 0.0016
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.1047 0.5334 0.5334
Loa Loa (eye worm) hypothetical protein 0.0022 0.0031 0.0031
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.003 0.0071 0.035
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0019 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Echinococcus multilocularis c4b binding protein beta chain 0.0043 0.0136 0.0136
Plasmodium vivax ataxin-2 like protein, putative 0.0039 0.0114 0.0693
Echinococcus multilocularis Protein lozenge 0.0127 0.0574 0.0574
Leishmania major cathepsin L-like protease 0.0075 0.0301 0.03
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.003 0.0071 0.0295
Trypanosoma brucei heat shock protein, putative 0.003 0.0071 0.0068
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0019 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0216 0.1033 0.1033
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.003 0.0071 0.0116
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.0212 0.0212
Echinococcus granulosus serotonin transporter 0.0109 0.0482 0.0482
Leishmania major heat shock protein 83-1 0.003 0.0071 0.007
Schistosoma mansoni loxhd1 0.0022 0.0031 0.0043
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0122 0.0544 0.074
Onchocerca volvulus 0.0036 0.0099 0.0171
Schistosoma mansoni ferritin light chain 0.0027 0.0054 0.0074
Leishmania major cathepsin L-like protease 0.002 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0011
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0152 0.0701 0.4373
Trichomonas vaginalis heat shock protein, putative 0.003 0.0071 0.0108
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0023 0.0034 0.0034
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0477 0.2384 0.2384
Brugia malayi hypothetical protein 0.0039 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0016 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.013 0.0587 0.1077
Loa Loa (eye worm) hypothetical protein 0.0036 0.0104 0.0104
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0122 0.0544 0.1033
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0057 0.0212 0.0212
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.003 0.0071 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.0152 0.0701 0.0698
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0342 0.1686 1
Mycobacterium tuberculosis Possible two component sensor kinase 0.003 0.0071 0.035
Loa Loa (eye worm) hypothetical protein 0.0217 0.1039 0.1039
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1047 0.5334 1
Brugia malayi Probable DNA topoisomerase II 0.003 0.0071 0.0071
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0587 0.1077
Toxoplasma gondii DNA topoisomerase 2, putative 0.003 0.0071 0.0149
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.004 0.0123 0.0122
Mycobacterium tuberculosis Conserved protein 0.0036 0.0099 0.0511
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0016 0.0029
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.1047 0.5334 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0057 0.0212 0.0212
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0066 0.0257 0.0257
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0152 0.0701 0.0701
Echinococcus granulosus expressed protein 0.0027 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.013 0.0588 0.0588
Onchocerca volvulus Huntingtin homolog 0.0296 0.1448 0.2784
Onchocerca volvulus Peroxidase homolog 0.013 0.0588 0.1117
Brugia malayi Pleckstrin Homology Domain 0.0023 0.0034 0.0034
Echinococcus multilocularis peroxidasin 0.013 0.0588 0.0588
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0099 0.0511
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0019 0.0011 0.0011
Loa Loa (eye worm) latrophilin receptor protein 2 0.0069 0.027 0.027
Toxoplasma gondii hypothetical protein 0.0895 0.4548 1
Toxoplasma gondii heat shock protein HSP90 0.003 0.0071 0.0149

Activities

Activity type Activity value Assay description Source Reference
Hill coefficient (binding) = 1.01 Hill coefficient of the compound was determined ChEMBL. No reference
IC50 (binding) = 21.4 nM The compound was tested for its affinity at the rat striatal dopamine transporter by the displacement of [3H]-WIN- 35,428 ChEMBL. No reference
Ratio (binding) = 5 Ratio of inhibitory concentration of compound 5c to 6c ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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