Detailed information for compound 235748

Basic information

Technical information
  • TDR Targets ID: 235748
  • Name: (E)-3-(3,4-dihydroxy-2-nitrophenyl)prop-2-eno ic acid
  • MW: 225.155 | Formula: C9H7NO6
  • H donors: 3 H acceptors: 6 LogP: 1.54 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)/C=C/c1ccc(c(c1[N+](=O)[O-])O)O
  • InChi: 1S/C9H7NO6/c11-6-3-1-5(2-4-7(12)13)8(9(6)14)10(15)16/h1-4,11,14H,(H,12,13)/b4-2+
  • InChiKey: YVHYIRDQBLOLCJ-DUXPYHPUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (E)-3-(3,4-dihydroxy-2-nitro-phenyl)prop-2-enoic acid
  • (E)-3-(3,4-dihydroxy-2-nitrophenyl)-2-propenoic acid
  • (E)-3-(3,4-dihydroxy-2-nitro-phenyl)acrylic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0054 0.024 0.0465
Echinococcus multilocularis lamin 0.0058 0.0264 0.0264
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0028 0.009 0.1173
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0163 0.0192
Loa Loa (eye worm) nuclear hormone receptor 0.0429 0.2394 0.4644
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0048 0.0048
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.009 0.015
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0294
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0184 0.0217
Loa Loa (eye worm) hypothetical protein 0.0477 0.267 0.5179
Onchocerca volvulus 0.0054 0.024 0.0465
Echinococcus granulosus GPCR family 2 0.0017 0.0026 0.0031
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.091 0.5155 0.5155
Trypanosoma cruzi Emopamil binding protein, putative 0.0149 0.0786 0.1698
Trypanosoma brucei C-8 sterol isomerase, putative 0.0799 0.4517 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0184 0.0217
Brugia malayi M-phase phosphoprotein, mpp8 0.0109 0.0555 0.1077
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0054 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.008 0.0188
Brugia malayi Cytochrome P450 family protein 0.0019 0.0039 0.0075
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0111 0.0568 0.0668
Onchocerca volvulus 0.0039 0.0151 0.0294
Brugia malayi hypothetical protein 0.0109 0.0556 0.1079
Loa Loa (eye worm) SRC-1 0.0041 0.0163 0.0317
Entamoeba histolytica hypothetical protein 0.0039 0.0151 0.1979
Echinococcus multilocularis g protein coupled receptor 0.0054 0.024 0.024
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0188
Schistosoma mansoni cytochrome P450 0.0019 0.0039 0.0046
Brugia malayi hypothetical protein 0.0477 0.267 0.5179
Echinococcus granulosus g-protein coupled receptor 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0117 0.0117
Onchocerca volvulus 0.0429 0.2394 0.4644
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.002 0.002
Brugia malayi conserved hypotetical protein 0.0429 0.2394 0.4644
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0041 0.0165 0.2556
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0041 0.0165 0.0194
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Brugia malayi Death domain containing protein 0.0016 0.0018 0.0035
Loa Loa (eye worm) hypothetical protein 0.0799 0.4517 0.8763
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.034 0.0706
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0184 0.0358
Echinococcus multilocularis cpg binding protein 0.0066 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0481 0.269 0.5218
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0053 0.0191
Echinococcus multilocularis somatostatin receptor 0.0054 0.024 0.024
Mycobacterium ulcerans endonuclease IV 0.0083 0.0403 0.1445
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0045 0.0184 0.0217
Schistosoma mansoni hypothetical protein 0.0037 0.014 0.0164
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0054 0.024 0.0465
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.024 0.0282
Loa Loa (eye worm) phospholipase D 0.0021 0.005 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0116 0.0274
Echinococcus granulosus allatostatin A receptor 0.0054 0.024 0.0282
Brugia malayi ecdysone receptor 0.0429 0.2394 0.4644
Trypanosoma cruzi cardiolipin synthetase, putative 0.0039 0.0152 0.0288
Trichomonas vaginalis glucosylceramidase, putative 0.0367 0.2033 0.4787
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0111 0.0568 0.2035
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0209 0.0491
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0083 0.0403 0.2051
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0039 0.0197
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0184 0.2407
Loa Loa (eye worm) hypothetical protein 0.091 0.5155 1
Plasmodium falciparum transporter, putative 0.0045 0.0184 0.2919
Brugia malayi Nuclear hormone receptor family member nhr-25 0.091 0.5155 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0054 0.024 0.0282
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.024 0.0282
Brugia malayi hypothetical protein 0.0045 0.0184 0.0358
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0054 0.024 0.0282
Schistosoma mansoni alpha-1 adrenergic receptor 0.0054 0.024 0.0282
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0184 0.2407
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0067 0.01
Brugia malayi putative neuropeptide receptor NPR1 0.0054 0.024 0.0465
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0026 0.0034
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0151 0.0771
Trichomonas vaginalis glucosylceramidase, putative 0.0367 0.2033 0.4787
Brugia malayi SET domain containing protein 0.0015 0.0014 0.0027
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0039 0.0197
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0086 0.0141
Brugia malayi AKH receptor 0.0054 0.024 0.0465
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0227 0.1233 0.2392
Trichomonas vaginalis glucosylceramidase, putative 0.0386 0.2146 0.5054
Brugia malayi cytochrome P450 0.0019 0.0039 0.0075
Schistosoma mansoni sodium/chloride dependent transporter 0.0045 0.0184 0.0217
Trichomonas vaginalis glucosylceramidase, putative 0.0559 0.3136 0.7384
Mycobacterium ulcerans oxidoreductase 0.0024 0.0067 0.0242
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0024 0.0028
Echinococcus multilocularis dro:myosuppressin receptor 0.0054 0.024 0.024
Onchocerca volvulus 0.0046 0.0193 0.0374
Onchocerca volvulus 0.091 0.5155 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0041 0.0163 0.0163
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0151 0.0178
Echinococcus granulosus phospholipase D1 0.0112 0.057 0.067
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.024 0.0282
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0067 0.01
Echinococcus granulosus phospholipase D 0.0099 0.0495 0.0582
Loa Loa (eye worm) hypothetical protein 0.0074 0.0351 0.0681
Echinococcus granulosus biogenic amine 5HT receptor 0.0054 0.024 0.0282
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0683 0.2448
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0018 0.0031 0.0037
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0124 0.0641 0.3263
Onchocerca volvulus 0.0058 0.0264 0.0511
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0151 0.0543
Leishmania major ferredoxin 2fe-2s-like protein 0.0024 0.0067 0.01
Mycobacterium tuberculosis Possible oxygenase 0.0024 0.0067 0.0343
Echinococcus granulosus neuropeptide receptor 0.0054 0.024 0.0282
Echinococcus granulosus nuclear receptor 2DBD gamma 0.091 0.5155 0.6065
Schistosoma mansoni amine GPCR 0.0054 0.024 0.0282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0187
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0184 0.2407
Schistosoma mansoni retinoid-x-receptor (RXR) 0.091 0.5155 0.6065
Brugia malayi Nuclear hormone receptor E75 0.0429 0.2394 0.4644
Loa Loa (eye worm) hypothetical protein 0.0073 0.0346 0.0671
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0683 0.0803
Loa Loa (eye worm) hypothetical protein 0.0481 0.269 0.5218
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Onchocerca volvulus 0.0259 0.1413 0.2741
Loa Loa (eye worm) TK protein kinase 0.0033 0.0117 0.0227
Schistosoma mansoni amine GPCR 0.0414 0.2303 0.271
Leishmania major cytochrome p450-like protein 0.0038 0.0148 0.0278
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0122 0.1463
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Plasmodium falciparum ferredoxin, putative 0.0024 0.0067 0.0759
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0111 0.0568 0.0668
Schistosoma mansoni tyrosine kinase 0.0041 0.0163 0.0192
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0173 0.0203
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0148 0.0303
Schistosoma mansoni cellular tumor antigen P53 0.0107 0.0543 0.0639
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0028 0.009 0.009
Onchocerca volvulus 0.0054 0.024 0.0465
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0054 0.024 0.0282
Brugia malayi Carboxylesterase family protein 0.0074 0.0351 0.0681
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0041 0.0165 0.0316
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.024 0.0282
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0481 0.269 0.269
Echinococcus granulosus 7tm_1 domain containing protein 0.0054 0.024 0.0282
Leishmania major C-8 sterol isomerase-like protein 0.0799 0.4517 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0026 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0178 0.0418
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0184 0.0358
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0022
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0045 0.0184 0.0217
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.091 0.5155 0.5155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.011 0.026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0151 0.0178
Schistosoma mansoni nuclear receptor 0.0429 0.2394 0.2817
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0024 0.0067 0.0343
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.024 0.0282
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0111 0.0568 0.1336
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0173 0.2703
Trichomonas vaginalis glucosylceramidase, putative 0.0367 0.2033 0.4787
Brugia malayi hypothetical protein 0.0481 0.269 0.5218
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0026 0.0026
Echinococcus multilocularis G-protein coupled receptor, putative 0.0054 0.024 0.024
Trypanosoma brucei electron transfer protein, putative 0.0024 0.0067 0.0125
Echinococcus multilocularis fmrfamide receptor 0.0054 0.024 0.024
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.024 0.024
Trichomonas vaginalis glucosylceramidase, putative 0.0386 0.2146 0.5054
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Onchocerca volvulus 0.0054 0.024 0.0465
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0163 0.0192
Onchocerca volvulus 0.0054 0.024 0.0465
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0061 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0022
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.091 0.5155 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0048 0.0245
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0046 0.0054
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0157 0.0157
Toxoplasma gondii endonuclease IV APN 0.0083 0.0403 0.5738
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0024 0.0067 0.01
Echinococcus granulosus biogenic amine 5HT receptor 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Brugia malayi Nuclear hormone receptor family member nhr-19 0.091 0.5155 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.0039 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Echinococcus multilocularis ecdysone induced protein 78C 0.091 0.5155 0.5155
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.009 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0467 0.0906
Echinococcus multilocularis phospholipase D 0.0099 0.0495 0.0495
Loa Loa (eye worm) acetylcholinesterase 1 0.0074 0.0351 0.0681
Onchocerca volvulus 0.0054 0.024 0.0465
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0022
Loa Loa (eye worm) hypothetical protein 0.0045 0.0184 0.0358
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0018 0.0035
Brugia malayi nuclear hormone receptor family member nhr-6 0.0429 0.2394 0.4644
Loa Loa (eye worm) hypothetical protein 0.091 0.5155 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Trichomonas vaginalis Ferredoxin 7 0.0024 0.0067 0.0159
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0097 0.0485 0.0485
Loa Loa (eye worm) hypothetical protein 0.0109 0.0555 0.1077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.024 0.0282
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0403 0.6958
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0054 0.024 0.0465
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.024 0.0465
Loa Loa (eye worm) hypothetical protein 0.0043 0.0173 0.0335
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0045 0.0184 0.0217
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.014 0.014
Schistosoma mansoni netrin receptor unc5 0.0016 0.0018 0.0021
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0046 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-31 0.091 0.5155 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.024 0.0282
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.002 0.0023
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0116 0.0593 0.1151
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0039 0.0197
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0752 0.4247 1
Schistosoma mansoni hypothetical protein 0.0016 0.0018 0.0021
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0387 0.0456
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0209 0.3079
Schistosoma mansoni hypothetical protein 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0054 0.0237 0.046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0004 0.0009
Echinococcus granulosus nuclear receptor nhr 48 0.0429 0.2394 0.2817
Brugia malayi Melatonin receptor type 1A 0.0054 0.024 0.0465
Leishmania major solanesyl-diphosphate synthase, putative 0.0028 0.009 0.015
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0111 0.0568 0.1213
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.01
Toxoplasma gondii ferredoxin, putative 0.0024 0.0067 0.0625
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0024 0.0067 0.0625
Schistosoma mansoni cpg binding protein 0.0066 0.0306 0.036
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0023 0.0023
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0048 0.0172
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus granulosus RUN 0.0043 0.0173 0.0203
Brugia malayi Tachykinin-like peptides receptor 99D 0.0054 0.024 0.0465
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0163 0.0163
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0054 0.024 0.0465
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0053
Loa Loa (eye worm) hypothetical protein 0.0045 0.0184 0.0358
Onchocerca volvulus 0.0054 0.024 0.0465
Brugia malayi Phospholipase D. Active site motif family protein 0.0021 0.005 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0137 0.0322
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0018 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Brugia malayi CHD4 protein 0.0016 0.002 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0053 0.0104
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0028 0.009 0.0802
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0193 0.0227
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.024 0.0282
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0209 0.0405
Brugia malayi putative neuropeptide receptor 0.0054 0.024 0.0465
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0026 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0094 0.0222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.091 0.5155 1
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0167 0.0167
Echinococcus multilocularis fmrfamide receptor 0.0054 0.024 0.024
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0028 0.009 0.0457
Onchocerca volvulus 0.0043 0.0173 0.0335
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0429 0.2394 0.4644
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0024 0.0067 0.0067
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.009 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0178 0.0344
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.091 0.5155 0.5155
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0054 0.024 0.0465
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0028 0.009 0.0322
Echinococcus granulosus phospholipase d3 0.0021 0.005 0.0058
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0429 0.2394 0.4644
Schistosoma mansoni sodium-dependent amino acid transporter 0.0045 0.0184 0.0217
Trichomonas vaginalis glucosylceramidase, putative 0.0367 0.2033 0.4787
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.024 0.0282
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.014 0.0165
Echinococcus granulosus lamin 0.0058 0.0264 0.031
Echinococcus multilocularis serotonin receptor 0.0054 0.024 0.024
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0151 0.0771
Schistosoma mansoni growth hormone secretagogue receptor 0.0054 0.024 0.0282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0137 0.0322
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0254 0.1387 0.4971
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0041 0.0165 0.032
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0026 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0096 0.0226
Echinococcus granulosus neuropeptide receptor 0.0054 0.024 0.0282
Echinococcus multilocularis FTZ F1 alpha 0.091 0.5155 0.5155
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0429 0.2394 0.2394
Onchocerca volvulus 0.0045 0.0184 0.0358
Echinococcus granulosus tm gpcr rhodopsin 0.0616 0.3464 0.4076
Entamoeba histolytica hypothetical protein 0.0039 0.0151 0.1979
Brugia malayi ecdysteroid receptor 0.091 0.5155 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.091 0.5155 0.6065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Echinococcus granulosus fmrfamide receptor 0.0054 0.024 0.0282
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.0039 0.0139
Echinococcus granulosus Nuclear hormone receptor HR96 0.0429 0.2394 0.2817
Brugia malayi Nuclear hormone receptor family member nhr-25 0.091 0.5155 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.0039 0.0139
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.024 0.0465
Schistosoma mansoni polycystin 1-related 0.0043 0.0173 0.0203
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0048 0.0082
Treponema pallidum hypothetical protein 0.0122 0.0631 0.4019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.024 0.024
Loa Loa (eye worm) TK protein kinase 0.0037 0.014 0.0272
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0152 0.0312
Brugia malayi protein-tyrosine kinase 0.0037 0.014 0.0272
Echinococcus multilocularis neuropeptide s receptor 0.055 0.3087 0.3087
Loa Loa (eye worm) hypothetical protein 0.0027 0.0086 0.0166
Loa Loa (eye worm) hypothetical protein 0.091 0.5155 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0209 0.0414
Schistosoma mansoni cpg binding protein 0.0066 0.0306 0.036
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0044 0.0086
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0157 0.0185
Brugia malayi hypothetical protein 0.0429 0.2394 0.4644
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0022
Mycobacterium leprae Probable lipase LipE 0.0039 0.0151 0.3095
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0041 0.0165 0.0341
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0086 0.0903
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0429 0.2394 0.4644
Onchocerca volvulus 0.0054 0.024 0.0465
Schistosoma mansoni lamin 0.0058 0.0264 0.031
Brugia malayi Steroid receptor seven-up type 2 0.091 0.5155 1
Mycobacterium ulcerans oxygenase 0.0024 0.0067 0.0242
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.091 0.5155 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0054 0.024 0.0282
Echinococcus granulosus geminin 0.0183 0.0977 0.115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0137 0.0322
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0173 0.0203
Onchocerca volvulus 0.0039 0.0151 0.0294
Loa Loa (eye worm) hypothetical protein 0.0043 0.0178 0.0344
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0144 0.0753 0.3833
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0294
Brugia malayi hypothetical protein 0.0043 0.0173 0.0335
Echinococcus granulosus dnaJ subfamily B 0.0885 0.5009 0.5893
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.091 0.5155 0.6065
Onchocerca volvulus 0.0054 0.024 0.0465
Echinococcus multilocularis 0.0019 0.0039 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0178 0.0209
Schistosoma mansoni hypothetical protein 0.0039 0.0151 0.0178
Brugia malayi steroid hormone receptor 0.091 0.5155 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0124 0.0641 0.2299
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.0039 0.0139
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0148 0.0286
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0149 0.0786 0.1698
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0683 0.2448
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0035
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.014 0.014
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0028 0.009 0.0174
Onchocerca volvulus 0.0262 0.1435 0.2784
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0111 0.0568 0.2889
Leishmania major DNA polymerase eta, putative 0.0021 0.0048 0.0057
Echinococcus multilocularis phospholipase D1 0.0112 0.057 0.057
Brugia malayi Cytochrome P450 family protein 0.0038 0.0148 0.0286
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0041 0.0165 0.032
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.091 0.5155 1
Giardia lamblia [2Fe-2S] ferredoxin 0.0024 0.0067 0.0373
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0429 0.2394 0.2394
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0209 0.0439
Echinococcus granulosus microtubule associated protein 2 0.1493 0.8499 1
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0111 0.0568 0.2035
Brugia malayi nuclear hormone receptor 0.0429 0.2394 0.4644
Schistosoma mansoni amine GPCR 0.0054 0.024 0.0282
Plasmodium vivax SET domain protein, putative 0.0034 0.0122 0.1774
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0054 0.024 0.0282
Trichomonas vaginalis helicase, putative 0.0014 0.0009 0.0022
Echinococcus multilocularis geminin 0.0183 0.0977 0.0977
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0178 0.2483
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0054 0.024 0.0282
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0028 0.009 0.015
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0294
Echinococcus multilocularis g-protein coupled receptor 0.0054 0.024 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0168 0.0395
Onchocerca volvulus 0.0149 0.0786 0.1524
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0209 0.0439
Brugia malayi nuclear receptor RXR 0.0481 0.269 0.5218
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0054 0.024 0.024
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0151 0.0771
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0024 0.0067 0.01
Chlamydia trachomatis ferredoxin 0.0024 0.0067 0.0974
Echinococcus multilocularis neuropeptide FF receptor 2 0.0054 0.024 0.024
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.009 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.024 0.024
Onchocerca volvulus 0.0109 0.0555 0.1077
Loa Loa (eye worm) hypothetical protein 0.091 0.5155 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.091 0.5155 0.6065
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.008 0.0188
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.024 0.024
Trichomonas vaginalis glucosylceramidase, putative 0.0559 0.3136 0.7384
Schistosoma mansoni lipoxygenase 0.011 0.0561 0.066
Echinococcus multilocularis dna polymerase eta 0.0021 0.0048 0.0048
Schistosoma mansoni amine GPCR 0.0054 0.024 0.0282
Echinococcus granulosus carboxylesterase 5A 0.0074 0.0351 0.0413
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0148 0.0529
Leishmania major cytochrome p450-like protein 0.0019 0.0039 0.0036
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0037
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0173 0.0335
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.0039 0.0139
Mycobacterium ulcerans beta-lactamase 0.0039 0.0151 0.0543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0187
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0209 0.0209
Echinococcus granulosus intermediate filament protein 0.0058 0.0264 0.031
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.091 0.5155 0.6065
Schistosoma mansoni phospholipase D 0.0112 0.057 0.067
Loa Loa (eye worm) hypothetical protein 0.0375 0.2082 0.4039
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.014 0.014
Brugia malayi Cytochrome P450 family protein 0.0038 0.0148 0.0286
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0223 0.1209 0.4334
Brugia malayi Phospholipase D. Active site motif family protein 0.0039 0.0152 0.0295
Echinococcus multilocularis lamin dm0 0.0058 0.0264 0.0264
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.091 0.5155 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Treponema pallidum sodium- and chloride- dependent transporter 0.0262 0.1435 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Brugia malayi Dopamine receptor 0.0054 0.024 0.0465
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0045 0.0184 0.4119
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0026 0.0051
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0184 0.2919
Toxoplasma gondii ferodoxin FD 0.0024 0.0067 0.0625
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.091 0.5155 1
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0254 0.1387 0.7058
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0041 0.0165 0.0388
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0184 0.0217
Brugia malayi Nuclear hormone receptor family member nhr-19 0.091 0.5155 1
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0024 0.0067 0.0242
Schistosoma mansoni sodium/chloride dependent transporter 0.0045 0.0184 0.0217
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0151 0.0178
Schistosoma mansoni myosin xvIII 0.0054 0.024 0.0282
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0403 0.6958
Onchocerca volvulus 0.0024 0.0067 0.0131
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0054 0.024 0.0282
Brugia malayi G-protein coupled receptor 0.0054 0.024 0.0465
Echinococcus granulosus serotonin transporter 0.0262 0.1435 0.1689
Brugia malayi follicle stimulating hormone receptor 0.0054 0.024 0.0465
Mycobacterium tuberculosis Conserved protein 0.0039 0.0151 0.0771
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0048 0.0082
Onchocerca volvulus 0.0054 0.024 0.0465
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0054 0.024 0.0465
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0054 0.024 0.0465
Brugia malayi GnHR receptor homolog 0.0054 0.024 0.0465
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0151 0.0151
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0209 0.0245
Mycobacterium ulcerans lipase LipD 0.0039 0.0151 0.0543
Brugia malayi larval opioid receptor 0.0054 0.024 0.0465
Onchocerca volvulus 0.0062 0.0285 0.0553
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0023 0.0027
Schistosoma mansoni biogenic amine (5HT) receptor 0.0054 0.024 0.0282
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0024 0.0024
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0124 0.0641 0.0641
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0429 0.2394 0.2817
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0024 0.0067 0.0131
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0023 0.0026
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0045 0.0184 0.0184
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.009 0.015
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0028 0.009 0.0106
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0799 0.4517 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0237 0.046
Loa Loa (eye worm) hypothetical protein 0.0037 0.014 0.0271
Echinococcus granulosus G protein coupled receptor 139 0.0054 0.024 0.0282
Brugia malayi Cytochrome P450 family protein 0.0061 0.0277 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0137 0.0322
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0048 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.024 0.0282
Onchocerca volvulus Putative phospholipase D 0.0021 0.005 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0039 0.0197
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.008 0.0188
Leishmania major polyprenyl synthase, putative 0.0028 0.009 0.015
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0018 0.0021
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0028 0.009 0.0457
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.008 0.0188
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0048 0.0057
Brugia malayi hypothetical protein 0.0018 0.003 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0559 0.3136 0.7384
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0041 0.0163 0.0192
Brugia malayi hypothetical protein 0.0039 0.0151 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0053
Echinococcus multilocularis RUN 0.0043 0.0173 0.0173
Trypanosoma brucei cardiolipin synthetase, putative 0.0039 0.0152 0.0313
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0137 0.1683
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0148 0.0286
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0111 0.0568 0.1336
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0481 0.269 0.3165
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0178 0.0418
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0097 0.0485 0.057
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0151 0.0771
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0026 0.0034
Echinococcus multilocularis serotonin receptor 0.0054 0.024 0.024
Echinococcus granulosus sex peptide receptor 0.0054 0.024 0.0282
Brugia malayi Nuclear hormone receptor family member nhr-49 0.091 0.5155 1
Echinococcus granulosus death domain containing protein 0.0016 0.0018 0.0021
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0683 0.0803
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0022
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0048 0.0057
Loa Loa (eye worm) TYRA-2 protein 0.0054 0.024 0.0465
Brugia malayi beta-lactamase family protein 0.0039 0.0151 0.0294
Loa Loa (eye worm) hypothetical protein 0.0028 0.009 0.0175
Echinococcus granulosus dna polymerase eta 0.0021 0.0048 0.0057
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0024 0.0067 0.0759
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0054 0.024 0.024
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.091 0.5155 0.6065
Brugia malayi neuropeptide F receptor 0.0054 0.024 0.0465
Schistosoma mansoni nuclear receptor nhr-48 0.0429 0.2394 0.2817
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0151 0.0357
Mycobacterium ulcerans hypothetical protein 0.0022 0.0053 0.0191
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0124 0.0641 0.0754
Schistosoma mansoni glutathione synthetase 0.0028 0.009 0.0106
Brugia malayi Nuclear hormone receptor-like 1 0.0481 0.269 0.5218
Chlamydia trachomatis endonuclease IV 0.0083 0.0403 1
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0094 0.0467 0.0906
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0122 0.0144
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0151 0.0357
Schistosoma mansoni neuropeptide receptor 0.0054 0.024 0.0282
Brugia malayi Polyprenyl synthetase family protein 0.0111 0.0568 0.1101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0096 0.0226
Schistosoma mansoni neuropeptide f receptor 76f 0.0054 0.024 0.0282
Brugia malayi Doublecortin family protein 0.0043 0.0173 0.0335
Loa Loa (eye worm) hypothetical protein 0.091 0.5155 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0022
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0053
Brugia malayi nuclear receptor NHR-88 0.091 0.5155 1
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0028 0.009 0.0802
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0151 0.0287
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.0039 0.0139
Echinococcus granulosus thyroid hormone receptor alpha 0.0429 0.2394 0.2817
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0041 0.0165 0.0165
Loa Loa (eye worm) serotonin transporter b 0.0262 0.1435 0.2784
Schistosoma mansoni neuropeptide receptor 0.0054 0.024 0.0282
Schistosoma mansoni amine GPCR 0.0054 0.024 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0022
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0023 0.0044
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0148 0.0286
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.024 0.0465
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.091 0.5155 1
Loa Loa (eye worm) hypothetical protein 0.0477 0.267 0.5179
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0054 0.024 0.0282
Echinococcus granulosus nuclear receptor 2DBD gamma 0.091 0.5155 0.6065
Echinococcus multilocularis tumor protein p63 0.0731 0.4125 0.4125
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0122 0.0122
Loa Loa (eye worm) cytochrome P450 0.0019 0.0039 0.0075
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0355 0.1965 1
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0019 0.0022
Schistosoma mansoni thyroid hormone receptor 0.091 0.5155 0.6065
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0048 0.0082
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0616 0.3464 0.3464
Onchocerca volvulus Bile acid receptor homolog 0.091 0.5155 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0184 0.0358
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0086 0.1095
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0028 0.009 0.0106
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0178 0.037
Plasmodium vivax cardiolipin synthetase, putative 0.0018 0.0031 0.0089
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0163 0.0192
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus granulosus alpha 1A adrenergic receptor 0.0054 0.024 0.0282
Trypanosoma brucei cardiolipin synthetase 0.0039 0.0152 0.0313
Schistosoma mansoni hypothetical protein 0.0056 0.0251 0.0295
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0024 0.0024
Brugia malayi Serotonin receptor 0.0054 0.024 0.0465
Brugia malayi G-protein coupled receptor 0.0054 0.024 0.0465
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.009 0.015
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0209 0.0414
Schistosoma mansoni nuclear hormone receptor 0.0429 0.2394 0.2817
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0151 0.0356
Echinococcus granulosus orexin receptor type 2 0.0054 0.024 0.0282
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0209 0.0414
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.024 0.0282
Loa Loa (eye worm) carboxylesterase 0.0074 0.0351 0.0681
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0026 0.0134
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Onchocerca volvulus 0.0477 0.267 0.5179
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0054 0.024 0.024
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0163 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0188
Trichomonas vaginalis Ferredoxin 2 0.0024 0.0067 0.0159
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.024 0.0282
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0026 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0188
Echinococcus granulosus g protein coupled receptor 0.0054 0.024 0.0282
Echinococcus granulosus ecdysone induced protein 78C 0.091 0.5155 0.6065
Echinococcus multilocularis sodium and chloride dependent glycine 0.0045 0.0184 0.0184
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0083 0.0403 0.0782
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0134 0.0157
Onchocerca volvulus 0.0054 0.024 0.0465
Brugia malayi Nuclear hormone receptor family member nhr-40 0.091 0.5155 1
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0028 0.009 0.0322
Echinococcus granulosus peptide allatostatin:somatostatin 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0045 0.0184 0.0358
Onchocerca volvulus 0.0054 0.024 0.0465
Brugia malayi Nuclear hormone receptor family member nhr-41 0.091 0.5155 1
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0026 0.0009
Schistosoma mansoni cpg binding protein 0.0062 0.0285 0.0336
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus multilocularis conserved hypothetical protein 0.0749 0.4228 0.4228
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.0039 0.0139
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0262 0.1435 0.2784
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.024 0.0282
Mycobacterium tuberculosis Conserved protein 0.0039 0.0151 0.0771
Echinococcus granulosus tyrosine protein kinase Src64B 0.0041 0.0163 0.0192
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0209 0.0245
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Brugia malayi Nuclear hormone receptor-like 1 0.091 0.5155 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0151 0.0178
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0026 0.0051
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.0039 0.0139
Schistosoma mansoni opsin-like receptor 0.0054 0.024 0.0282
Brugia malayi Dopamine receptor protein 1 0.0054 0.024 0.0465
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0026 0.0051
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.0039 0.0139
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0237 0.046
Leishmania major ferredoxin, 2fe-2s-like protein 0.0024 0.0067 0.01
Toxoplasma gondii ABC1 family protein 0.0039 0.0151 0.1905
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0111 0.0568 0.1235
Loa Loa (eye worm) hypothetical protein 0.0027 0.0084 0.0163
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0173 0.0173
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.0039 0.0139
Echinococcus multilocularis thyroid hormone receptor alpha 0.091 0.5155 0.5155
Loa Loa (eye worm) hypothetical protein 0.0074 0.0351 0.0681
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0018 0.0018
Echinococcus multilocularis G protein coupled receptor 139 0.0054 0.024 0.024
Echinococcus multilocularis Protein lozenge 0.006 0.0273 0.0273
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0054 0.024 0.024
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0151 0.0151
Echinococcus granulosus tumor protein p63 0.0731 0.4125 0.4854
Schistosoma mansoni lozenge 0.006 0.0273 0.0321
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.034 0.034
Schistosoma mansoni nuclear hormone receptor 0.0429 0.2394 0.2817
Echinococcus multilocularis sex peptide receptor 0.0054 0.024 0.024
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0178 0.0345
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.024 0.0282
Onchocerca volvulus 0.0054 0.024 0.0465
Schistosoma mansoni lamin 0.0058 0.0264 0.031
Schistosoma mansoni Tr4/Tr2 (homologue) 0.091 0.5155 0.6065
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0124 0.0641 0.1244
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0953 0.5399 0.5399
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0151 0.0287
Onchocerca volvulus 0.0054 0.024 0.0465
Echinococcus granulosus hypothetical protein 0.0803 0.4539 0.5341
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0264 0.0511
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Brugia malayi beta-lactamase 0.0039 0.0151 0.0294
Onchocerca volvulus 0.0054 0.024 0.0465
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0151 0.0312
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Schistosoma mansoni hypothetical protein 0.0017 0.0026 0.0031
Toxoplasma gondii hypothetical protein 0.0045 0.0184 0.2407
Schistosoma mansoni hypothetical protein 0.0017 0.0026 0.0031
Schistosoma mansoni retinoic acid receptor RXR 0.1017 0.5765 0.6783
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0048 0.0057
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0061
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.024 0.0465
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0387 0.0387
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0122 0.0144
Toxoplasma gondii histone lysine methyltransferase SET1 0.0119 0.0611 0.891
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.034 0.0706
Onchocerca volvulus Protein ultraspiracle homolog 0.091 0.5155 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0264 0.0511
Leishmania major hypothetical protein, conserved 0.0039 0.0151 0.0287
Echinococcus multilocularis dnaJ subfamily B 0.0885 0.5009 0.5009
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0045 0.0184 0.0358
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0039 0.0197
Loa Loa (eye worm) hypothetical protein 0.0262 0.1435 0.2784
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0048 0.0057
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0045 0.0184 0.0217
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0041 0.0163 0.0163
Schistosoma mansoni hypothetical protein 0.0054 0.024 0.0282
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0039 0.0197
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0054 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0054 0.024 0.0465
Onchocerca volvulus 0.0058 0.0264 0.0511
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0041 0.0165 0.0388
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0536 0.3004 0.3004
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0018 0.0035
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0157 0.0304
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0039 0.0046
Onchocerca volvulus 0.0054 0.024 0.0465
Schistosoma mansoni hypothetical protein 0.0183 0.0977 0.115
Schistosoma mansoni thyroid hormone receptor 0.091 0.5155 0.6065
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0178 0.0209
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0178 0.0209
Entamoeba histolytica hypothetical protein 0.0039 0.0151 0.1979
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.024 0.024
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0375 0.2082 0.4039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.091 0.5155 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0683 0.3475
Echinococcus granulosus neuropeptide FF receptor 2 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0058 0.0264 0.0511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0137 0.0322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0096 0.0226
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0051
Schistosoma mansoni nuclear receptor 0.0429 0.2394 0.2817
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0045 0.0184 0.0184
Trichomonas vaginalis esterase, putative 0.0039 0.0151 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0094 0.0222
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0144 0.0753 0.27
Brugia malayi tailless protein 0.0429 0.2394 0.4644
Loa Loa (eye worm) hypothetical protein 0.0375 0.2082 0.4039
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0074 0.0351 0.0413
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0173 0.0173
Schistosoma mansoni hypothetical protein 0.0054 0.024 0.0282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0151 0.0356
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0093
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0184 0.0217
Echinococcus granulosus Ankyrin 0.0016 0.0019 0.0022
Schistosoma mansoni hypothetical protein 0.0017 0.0026 0.0031
Brugia malayi Carboxylesterase family protein 0.0074 0.0351 0.0681
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0039 0.0062
Echinococcus granulosus lamin dm0 0.0058 0.0264 0.031
Brugia malayi hypothetical protein 0.0043 0.0173 0.0335
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.034 0.0659
Echinococcus multilocularis orexin receptor type 2 0.0054 0.024 0.024
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0173 0.2703
Mycobacterium ulcerans electron transfer protein 0.0024 0.0067 0.0242
Schistosoma mansoni steroid hormone receptor ad4bp 0.091 0.5155 0.6065
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus multilocularis neuropeptide receptor A26 0.055 0.3087 0.3087
Loa Loa (eye worm) hypothetical protein 0.0262 0.1435 0.2784
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.024 0.024
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.002 0.0023
Trichomonas vaginalis Ferredoxin 3 0.0024 0.0067 0.0159
Trichomonas vaginalis glucosylceramidase, putative 0.0367 0.2033 0.4787
Loa Loa (eye worm) DR-78 0.0429 0.2394 0.4644
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0187 0.1 0.1177
Echinococcus multilocularis g protein coupled receptor 0.0054 0.024 0.024
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0039 0.0188
Schistosoma mansoni intermediate filament proteins 0.0058 0.0264 0.031
Echinococcus multilocularis serotonin transporter 0.0262 0.1435 0.1435
Trichomonas vaginalis set domain proteins, putative 0.0258 0.1412 0.3325
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0148 0.0278
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0028 0.009 0.1577
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0111 0.0568 0.0568
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0026 0.0031
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0048 0.0048
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0024 0.0067 0.0125
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0048 0.0245
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0048 0.0093
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0026 0.0031
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0026 0.0026
Schistosoma mansoni biogenic amine receptor 0.0054 0.024 0.0282
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Mycobacterium ulcerans epimerase 0.0022 0.0053 0.0191
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0752 0.4247 1
Schistosoma mansoni tyrosine kinase 0.0041 0.0163 0.0192
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0151 0.0357
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.002 0.0038
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0111 0.0568 0.1336
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0163 0.0163
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0149 0.0786 0.1698
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0209 0.0414
Onchocerca volvulus 0.0045 0.0184 0.0358
Brugia malayi Pre-SET motif family protein 0.0034 0.0122 0.0237
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0124 0.0641 0.0754
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0086 0.1095
Brugia malayi isocitrate dehydrogenase 0.0017 0.0026 0.0051
Leishmania major hypothetical protein, conserved 0.0149 0.0786 0.1698
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0045 0.0075
Loa Loa (eye worm) hypothetical protein 0.0034 0.0122 0.0237
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0028 0.009 0.009
Brugia malayi Nuclear hormone receptor family member nhr-3 0.091 0.5155 1
Treponema pallidum quinoline 2-oxidoreductase 0.0119 0.0614 0.3898
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0054 0.024 0.0282
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0683 0.2448
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.008 0.0188
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.034 0.0706
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0152 0.0287
Trichomonas vaginalis glucosylceramidase, putative 0.0559 0.3136 0.7384
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0184 0.0358
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0142 0.0334
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0041 0.0165 0.032
Loa Loa (eye worm) hypothetical protein 0.0408 0.2274 0.4411
Brugia malayi hypothetical protein 0.0481 0.269 0.5218
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.091 0.5155 1
Brugia malayi hypothetical protein 0.0027 0.0086 0.0166
Loa Loa (eye worm) hypothetical protein 0.0045 0.0184 0.0358
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0054 0.024 0.0465
Mycobacterium ulcerans hypothetical protein 0.0039 0.0151 0.0543
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0151 0.3095
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0024 0.0067 0.0131
Echinococcus multilocularis acetylcholinesterase 0.0074 0.0351 0.0351
Brugia malayi Protein K4 0.0018 0.0031 0.0061
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0122 0.0144
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.024 0.0282
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0039 0.0197
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0048 0.0057
Schistosoma mansoni trans-prenyltransferase 0.0028 0.009 0.0106
Loa Loa (eye worm) norepinephrine transporter 0.0262 0.1435 0.2784
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0026 0.0051
Treponema pallidum hypothetical protein 0.0101 0.0507 0.3099
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0018 0.0031 0.0089
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0039 0.0036
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0799 0.4517 0.8763
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0026 0.0009
Trypanosoma cruzi Emopamil binding protein, putative 0.0149 0.0786 0.1698
Schistosoma mansoni nuclear hormone receptor 0.091 0.5155 0.6065
Brugia malayi sulfakinin receptor protein 0.0054 0.024 0.0465
Loa Loa (eye worm) hypothetical protein 0.0083 0.0403 0.0782
Brugia malayi intermediate filament protein 0.0058 0.0264 0.0511
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0039 0.0197
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0151 0.0357
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0041 0.0163 0.0163
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0048 0.0093
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Trypanosoma brucei Emopamil binding protein, putative 0.0149 0.0786 0.1719
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0067 0.01
Schistosoma mansoni microtubule-associated protein tau 0.1493 0.8499 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0294
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0178 0.0345
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0122 0.0122
Schistosoma mansoni biogenic amine receptor 0.0054 0.024 0.0282
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.0039 0.0139
Onchocerca volvulus 0.0039 0.0151 0.0294
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0067 0.0343
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0028 0.009 0.0802
Trichomonas vaginalis aldehyde oxidase, putative 0.0752 0.4247 1
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0111 0.0568 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0041 0.0163 0.0163
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.008 0.0188
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0039 0.0197
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0054 0.024 0.024
Schistosoma mansoni histamine h1 receptor 0.0054 0.024 0.0282
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.0039 0.0139
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0151 0.0178
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0023 0.0027
Brugia malayi ORL1-like opioid receptor 0.0054 0.024 0.0465
Loa Loa (eye worm) hypothetical protein 0.091 0.5155 1
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0039 0.0197
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0054 0.024 0.024
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0151 0.0543
Brugia malayi Pre-SET motif family protein 0.0227 0.1233 0.2392
Entamoeba histolytica protein kinase, putative 0.0033 0.0117 0.132
Echinococcus multilocularis sodium and chloride dependent glycine 0.0045 0.0184 0.0184
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0163 0.0163
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0028 0.009 0.1173
Echinococcus granulosus retinoic acid receptor rxr beta a 0.1017 0.5765 0.6783
Schistosoma mansoni sodium/chloride dependent transporter 0.0262 0.1435 0.1689
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0429 0.2394 0.2817
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0184 0.0217
Echinococcus multilocularis musashi 0.0058 0.0264 0.0264
Leishmania major hypothetical protein, conserved 0.0024 0.0067 0.01
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0028 0.009 0.0175
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Mycobacterium ulcerans electron transfer protein FdxB 0.0024 0.0067 0.0242
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0028 0.009 0.0967
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0163 0.0192
Onchocerca volvulus 0.0429 0.2394 0.4644
Brugia malayi nuclear hormone receptor family member odr-7 0.0429 0.2394 0.4644
Brugia malayi G protein-coupled receptor 0.0054 0.024 0.0465
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0053 0.0104
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0355 0.1965 0.7044
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0178 0.0209
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0037 0.0086
Giardia lamblia GTOR 0.0049 0.0209 0.3091
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0039 0.0197
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0429 0.2394 0.4644
Loa Loa (eye worm) runx1 0.006 0.0273 0.0529
Brugia malayi Serotonin receptor 0.0553 0.3106 0.6025
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0024 0.0067 0.6178
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.091 0.5155 0.5155
Brugia malayi photoreceptor-specific nuclear receptor 0.091 0.5155 1
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0039 0.0197
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.024 0.024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0481 0.269 0.5218
Loa Loa (eye worm) hypothetical protein 0.0021 0.005 0.0096
Loa Loa (eye worm) polyprenyl synthetase 0.0111 0.0568 0.1101
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0039 0.0197
Loa Loa (eye worm) steroid hormone receptor 0.091 0.5155 1
Trichomonas vaginalis glucosylceramidase, putative 0.0559 0.3136 0.7384
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0184 0.0217
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0163 0.0163
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0024 0.0067 0.0974
Trichomonas vaginalis glucosylceramidase, putative 0.0559 0.3136 0.7384
Echinococcus granulosus tyrosine kinase 0.0037 0.014 0.0165
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0178 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.024 0.0282
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.024 0.024
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.009 0.015
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.024 0.0282
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0054 0.024 0.0282
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0026 0.0026
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.024 0.024
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0054 0.024 0.0465
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0057 0.0257 0.0499
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Schistosoma mansoni rab6-interacting 0.0043 0.0173 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0022
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0053 0.0272
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0021 0.005 0.006
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0134 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0151 0.0356
Mycobacterium ulcerans oxidoreductase 0.0024 0.0067 0.0242
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0039 0.0197
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.024 0.0282
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0024 0.0067 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0367 0.2033 0.4787
Entamoeba histolytica phospholipase D, putative 0.0112 0.057 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.034 0.04
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0054 0.024 0.024
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0082
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0108 0.021
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0041 0.0165 0.0194
Loa Loa (eye worm) hypothetical protein 0.0027 0.0084 0.0163
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0178 0.0209
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.024 0.024
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0481 0.269 0.3165
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0054 0.024 0.0282
Trichomonas vaginalis Ferredoxin 6 0.0024 0.0067 0.0159
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0039 0.0036
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0024 0.0067 0.0343
Echinococcus multilocularis g protein coupled receptor 0.0054 0.024 0.024
Onchocerca volvulus 0.0107 0.0543 0.1053
Schistosoma mansoni DNA polymerase eta 0.0021 0.0048 0.0057
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0178 0.2492
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0148 0.0278
Schistosoma mansoni adenoreceptor 0.0054 0.024 0.0282
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0039 0.0197
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0167 0.0196
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Brugia malayi Protein kinase domain containing protein 0.0016 0.0018 0.0035
Loa Loa (eye worm) hypothetical protein 0.0109 0.0556 0.1079
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0137 0.0322
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.0039 0.0139
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0039 0.0197
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0054 0.024 0.0465
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0151 0.0294
Echinococcus granulosus sodium and chloride dependent glycine 0.0045 0.0184 0.0217
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.034 0.073
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0048 0.0113
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0151 0.0771
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.024 0.024
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0039 0.0152 0.1916
Onchocerca volvulus Neuropeptide F receptor homolog 0.0054 0.024 0.0465
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0024 0.0067 0.0131
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.024 0.024
Echinococcus granulosus dna polymerase kappa 0.0021 0.0048 0.0057
Schistosoma mansoni hypothetical protein 0.0017 0.0026 0.0031
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0481 0.269 0.5218
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0028 0.009 0.0174
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0054 0.024 0.0282
Plasmodium falciparum amino acid transporter, putative 0.0045 0.0184 0.2919
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0041 0.0165 0.032
Loa Loa (eye worm) hypothetical protein 0.0043 0.0173 0.0335
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.0039 0.0139
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0683 0.1469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0151 0.0356
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0073 0.0346 0.0671
Giardia lamblia Farnesyl diphosphate synthase 0.0111 0.0568 1
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0041 0.0165 0.0316
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0187 0.1 0.1
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.014 0.0165
Leishmania major hypothetical protein, conserved 0.0027 0.0086 0.0141
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.034 0.04
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.024 0.0282
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.091 0.5155 0.6065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0122 0.0144
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.008 0.0188
Loa Loa (eye worm) hypothetical protein 0.0262 0.1435 0.2784
Plasmodium vivax ferredoxin, putative 0.0024 0.0067 0.0759
Trichomonas vaginalis Ferredoxin 4 0.0024 0.0067 0.0159
Loa Loa (eye worm) solute carrier family 6 member 4 0.0262 0.1435 0.2784
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0178 0.0209
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0048 0.0113
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0254 0.1387 0.4971
Brugia malayi Nuclear hormone receptor family member nhr-14 0.091 0.5155 1
Mycobacterium tuberculosis Conserved protein 0.0039 0.0151 0.0771
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0683 0.0683
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.0039 0.0139
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0151 0.0357
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0041 0.0165 0.2237
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0026 0.0026
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0048 0.0057
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0041 0.0165 0.2556
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0028 0.009 0.1404
Schistosoma mansoni hypothetical protein 0.0054 0.024 0.0282
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0028 0.009 0.0106
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0026 0.0026
Leishmania major DNA polymerase kappa, putative 0.0021 0.0048 0.0057
Onchocerca volvulus 0.0109 0.0555 0.1077
Brugia malayi Nuclear hormone receptor family member nhr-1 0.091 0.5155 1
Schistosoma mansoni hypothetical protein 0.0183 0.0977 0.115
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0111 0.0568 0.8246
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0018 0.0031 0.0089
Echinococcus granulosus neuropeptide s receptor 0.055 0.3087 0.3632
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.091 0.5155 0.5155
Brugia malayi beta-lactamase family protein 0.0039 0.0151 0.0294
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0237 0.046
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.034 0.0659
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0151 0.2311
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0041 0.0165 0.0316
Echinococcus granulosus g protein coupled receptor 0.0054 0.024 0.0282
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0048 0.0172
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0124 0.0641 0.1376
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0178 0.0418
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0294
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0028 0.009 0.009
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0086 0.1095
Brugia malayi orphan nuclear receptor NR2E1 0.0429 0.2394 0.4644
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0173 0.0173
Brugia malayi RE15519p 0.0054 0.024 0.0465
Schistosoma mansoni opsin-like receptor 0.0054 0.024 0.0282
Schistosoma mansoni hypothetical protein 0.0885 0.5009 0.5893
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.024 0.0282
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0039 0.0036
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0375 0.2082 0.245
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0041 0.0163 0.0163
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0018 0.0031 0.0089
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0429 0.2394 0.2394
Onchocerca volvulus Glucosylceramidase homolog 0.0367 0.2033 0.3944
Schistosoma mansoni neuropeptide receptor 0.0054 0.024 0.0282
Leishmania major farnesyl pyrophosphate synthase 0.0111 0.0568 0.1213
Brugia malayi hypothetical protein 0.0429 0.2394 0.4644
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.091 0.5155 0.6065
Echinococcus granulosus Nuclear hormone receptor HR96 0.0429 0.2394 0.2817
Mycobacterium ulcerans hypothetical protein 0.0122 0.0631 0.2261
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0045 0.0184 0.0358
Echinococcus granulosus acetylcholinesterase 0.0074 0.0351 0.0413
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.091 0.5155 0.5155
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Loa Loa (eye worm) hypothetical protein 0.0039 0.0151 0.0294
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0108 0.021
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.0039 0.0139
Schistosoma mansoni adrenodoxin 0.0024 0.0067 0.0079
Loa Loa (eye worm) hypothetical protein 0.091 0.5155 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0048 0.0057
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0108 0.0127
Leishmania major cytochrome p450-like protein 0.0019 0.0039 0.0036
Brugia malayi nuclear hormone receptor 0.091 0.5155 1
Schistosoma mansoni zinc finger protein 0.0429 0.2394 0.2817
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.008 0.0188
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0028 0.009 0.0106
Loa Loa (eye worm) melatonin receptor type 1A 0.0054 0.024 0.0465
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0209 0.0491
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.024 0.0282
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0018 0.0018
Brugia malayi Dopamine receptor protein 2 0.0054 0.024 0.0465
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0692 0.0814
Schistosoma mansoni rab6-interacting 0.0043 0.0173 0.0203
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0264 0.0511
Echinococcus multilocularis neuropeptide receptor 0.0054 0.024 0.024
Schistosoma mansoni adrenodoxin 0.0024 0.0067 0.0079
Brugia malayi nuclear receptor NHR-67 0.0429 0.2394 0.4644
Echinococcus granulosus FTZ F1 alpha 0.091 0.5155 0.6065
Echinococcus multilocularis ferredoxin adrenodoxin 0.0024 0.0067 0.0067
Brugia malayi neuropeptide F receptor 0.0054 0.024 0.0465
Trichomonas vaginalis Ferredoxin 1 0.0024 0.0067 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0151 0.0356
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0039 0.0036
Loa Loa (eye worm) hypothetical protein 0.0045 0.0184 0.0358
Brugia malayi Phospholipase d protein 1 0.0112 0.057 0.1105
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.091 0.5155 0.6065
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0018 0.0021
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.0039 0.0139
Loa Loa (eye worm) polyprenyl synthetase 0.0028 0.009 0.0174
Loa Loa (eye worm) beta-lactamase 0.0039 0.0151 0.0294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0209 0.0405
Echinococcus multilocularis acetylcholinesterase 0.0074 0.0351 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0022
Brugia malayi Nuclear hormone receptor E75 0.0429 0.2394 0.4644
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0045 0.0184 0.0358
Brugia malayi hypothetical protein 0.0018 0.0031 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0187
Echinococcus granulosus g protein coupled receptor 0.0054 0.024 0.0282
Brugia malayi Nuclear hormone receptor-like 1 0.0481 0.269 0.5218
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0429 0.2394 0.2817
Schistosoma mansoni hypothetical protein 0.0019 0.0039 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0039 0.0197
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0117 0.0138
Echinococcus multilocularis GPCR, family 2 0.0017 0.0026 0.0026
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0481 0.269 0.3165
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0053 0.0402
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0111 0.0568 1
Loa Loa (eye worm) hypothetical protein 0.091 0.5155 1
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0028 0.009 0.0457
Echinococcus granulosus tm gpcr rhodopsin 0.0953 0.5399 0.6353
Echinococcus multilocularis allatostatin A receptor 0.0054 0.024 0.024
Echinococcus granulosus acetylcholinesterase 0.0074 0.0351 0.0413
Brugia malayi nuclear receptor NHR-88 0.0429 0.2394 0.4644
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0048 0.0093
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.014 0.0271
Trypanosoma brucei unspecified product 0.0021 0.0048 0.0082
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0045 0.0184 0.0184
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0683 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0043 0.01
Schistosoma mansoni lipoxygenase 0.0187 0.1 0.1177
Loa Loa (eye worm) hypothetical protein 0.0107 0.0543 0.1053
Brugia malayi Polyprenyl synthetase family protein 0.0028 0.009 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0188
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.024 0.0282
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0149 0.0786 0.1698
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0097 0.0485 0.057
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0083 0.0403 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0559 0.3136 0.6084
Loa Loa (eye worm) histone methyltransferase 0.002 0.0046 0.0089
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0248 0.1352 0.6883
Schistosoma mansoni biogenic amine receptor 0.0054 0.024 0.0282
Entamoeba histolytica phospholipase D, putative 0.0112 0.057 1
Echinococcus granulosus ferredoxin 0.0024 0.0067 0.0079
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0023 0.0026
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0355 0.1965 0.7044
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0151 0.0771
Brugia malayi nuclear receptor RXR 0.0429 0.2394 0.4644
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0124 0.0641 0.2299
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0067 0.01
Echinococcus granulosus cpg binding protein 0.0066 0.0306 0.036
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0429 0.2394 0.2394
Brugia malayi hypothetical protein 0.0054 0.024 0.0465
Brugia malayi Uncoordinated protein 44 0.0016 0.0018 0.0035
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0039 0.0197
Echinococcus multilocularis Ankyrin 0.0016 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0429 0.2394 0.4644
Schistosoma mansoni RAR-like nuclear receptor 0.091 0.5155 0.6065
Loa Loa (eye worm) nuclear receptor NHR-67 0.0429 0.2394 0.4644
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus granulosus serotonin receptor 0.0054 0.024 0.0282
Onchocerca volvulus 0.0045 0.0184 0.0358
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.0039 0.0139
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0429 0.2394 0.2817
Toxoplasma gondii hypothetical protein 0.0045 0.0184 0.2407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0209 0.0491
Echinococcus multilocularis microtubule associated protein 2 0.1493 0.8499 0.8499
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.0039 0.0139
Schistosoma mansoni loxhd1 0.0043 0.0173 0.0203
Echinococcus multilocularis carboxylesterase 5A 0.0074 0.0351 0.0351
Echinococcus granulosus neuropeptide receptor A26 0.055 0.3087 0.3632
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.0039 0.0139
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Echinococcus multilocularis neuropeptide receptor 0.0054 0.024 0.024
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0262 0.1435 0.1689
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.091 0.5155 1
Echinococcus granulosus dro:myosuppressin receptor 0.0054 0.024 0.0282
Schistosoma mansoni neuropeptide receptor 0.0054 0.024 0.0282
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0465
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0144 0.0753 0.27
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0178 0.0209
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0086 0.0166
Brugia malayi CXXC zinc finger family protein 0.0062 0.0285 0.0553
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0277 0.0536
Echinococcus granulosus tachykinin peptides receptor 99D 0.0054 0.024 0.0282
Echinococcus granulosus Adrenodoxin mitochondrial 0.0024 0.0067 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.024 0.0282
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0097 0.0485 0.057
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0498 0.2789 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0024 0.0028
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0142 0.0334
Schistosoma mansoni hypothetical protein 0.0043 0.0173 0.0203
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.024 0.0282
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0023 0.0044
Plasmodium vivax amine transporter, putative 0.0045 0.0184 0.2919
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0048 0.0082
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0178 0.0178
Leishmania major cardiolipin synthetase, putative 0.0018 0.0031 0.0019
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0041 0.0165 0.2107
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0151 0.0294
Loa Loa (eye worm) hypothetical protein 0.0045 0.0184 0.0358
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0285 0.0553
Trypanosoma cruzi cardiolipin synthetase, putative 0.0039 0.0152 0.0288
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0157 0.0304
Onchocerca volvulus 0.0054 0.024 0.0465
Loa Loa (eye worm) hypothetical protein 0.0481 0.269 0.5218
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0094 0.0467 0.8032
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0045 0.0184 0.0217
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0173 0.0203
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0086 0.0141
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0053 0.0104
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0045 0.0184 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.024 0.0282
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0039 0.0197
Brugia malayi SRC-1 0.0041 0.0163 0.0317
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0039 0.0197
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0024 0.0067 0.0242
Echinococcus multilocularis nuclear receptor nhr 48 0.0429 0.2394 0.2394
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0178 0.0345
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0152 0.0287
Onchocerca volvulus 0.0043 0.0173 0.0335
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0026 0.0031
Echinococcus granulosus sodium and chloride dependent glycine 0.0045 0.0184 0.0217
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.034 0.5597
Echinococcus granulosus somatostatin receptor 0.0054 0.024 0.0282
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0151 0.0771
Entamoeba histolytica hypothetical protein 0.0039 0.0151 0.1979
Schistosoma mansoni coup transcription factor 0.091 0.5155 0.6065
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0018 0.0031 0.0045
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.024 0.024
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0559 0.3136 0.6084
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0246
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0209 0.3079
Loa Loa (eye worm) hypothetical protein 0.0481 0.269 0.5218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0137 0.0322
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0111 0.0568 0.1213
Trichomonas vaginalis glucosylceramidase, putative 0.0367 0.2033 0.4787
Brugia malayi G protein-coupled receptor F59B2.13 0.0054 0.024 0.0465
Echinococcus multilocularis phospholipase d3 0.0021 0.005 0.005
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0683 0.0803
Schistosoma mansoni opsin-like receptor 0.0054 0.024 0.0282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0023 0.0053
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0041 0.0163 0.0192

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 35 uM Compound was evaluated for superoxide anion (O2-) scavenging activity ChEMBL. No reference
IC50 (binding) > 100 uM Inhibition of HIV1 integrase by ELISA ChEMBL. 18952420
IC50 (binding) = 425 uM Compound was evaluated for hydroxyl radical (OH) scavenging activity ChEMBL. No reference
Inhibition (binding) = 61 % Compound was evaluated for inhibition of xanthine oxidase ChEMBL. No reference
Inhibition (binding) = 61 % Compound was evaluated for inhibition of xanthine oxidase ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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