Detailed information for compound 283057

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 335.895 | Formula: C17H22ClN3S
  • H donors: 0 H acceptors: 1 LogP: 4.43 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=CCN1[C@@H](C)Cn2c3c([C@@H]1C)cc(Cl)cc3nc2S)C
  • InChi: 1S/C17H22ClN3S/c1-10(2)5-6-20-11(3)9-21-16-14(12(20)4)7-13(18)8-15(16)19-17(21)22/h5,7-8,11-12H,6,9H2,1-4H3,(H,19,22)/t11-,12-/m0/s1
  • InChiKey: SIUWCFHEUWWLTD-RYUDHWBXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0027 0.0103 0.0101
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Brugia malayi hypoxia-induced factor 1 0.0154 0.0983 0.1151
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.2888 0.2888
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0243 0.0243
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0042 0.0042
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0429 0.2888 0.2893
Leishmania major hypothetical protein, conserved 0.0033 0.0142 0.2003
Schistosoma mansoni diacylglycerol kinase theta 0.0165 0.1058 0.1058
Schistosoma mansoni synaptotagmin 0.0033 0.0142 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus multilocularis extended synaptotagmin 2 0.0033 0.0142 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Leishmania major hypothetical protein, conserved 0.0033 0.0142 0.2003
Loa Loa (eye worm) hypothetical protein 0.1023 0.7002 0.8597
Loa Loa (eye worm) hypothetical protein 0.0027 0.0103 0.0121
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0033 0.0142 0.7177
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Treponema pallidum ribonuclease H (rnhA) 0.0027 0.0101 1
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0019 0.005 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Brugia malayi AKH receptor 0.0429 0.2888 0.3422
Echinococcus granulosus neuropeptide receptor 0.0429 0.2888 0.2893
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0053 0.0046
Schistosoma mansoni amine GPCR 0.0429 0.2888 0.2888
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Echinococcus multilocularis synaptotagmin protein 4 0.0033 0.0142 0.0142
Onchocerca volvulus 0.0033 0.0142 0.0472
Loa Loa (eye worm) hypothetical protein 0.0167 0.1073 0.1313
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0165 0.1058 0.1059
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.1531 0.1531
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Trichomonas vaginalis adenylate cyclase, putative 0.0016 0.0028 0.0144
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0042 0.0207
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0429 0.2888 0.2888
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.1582 0.1584
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.1025 0.7018 0.7029
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0429 0.2888 0.2888
Echinococcus granulosus g protein coupled receptor 0.0429 0.2888 0.2893
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus granulosus protein piccolo 0.0033 0.0142 0.0142
Brugia malayi Latrophilin receptor protein 2 0.0016 0.003 0.0014
Echinococcus granulosus 7TM GPCR rhodopsin 0.0429 0.2888 0.2893
Echinococcus granulosus NDR protein kinase 0.0233 0.1531 0.1533
Schistosoma mansoni E3 ubiquitin-protein ligase nedd-4 0.0033 0.0142 0.0142
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0055 0.0062
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0429 0.2888 0.3422
Schistosoma mansoni neuropeptide F-like receptor 0.0429 0.2888 0.2888
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.002 0.0057 0.1941
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Trypanosoma brucei C2 domain containing protein, putative 0.0033 0.0142 0.0863
Brugia malayi Pre-SET motif family protein 0.0031 0.0132 0.0135
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0008 0.0008
Echinococcus granulosus importin subunit beta 1 0.0027 0.0104 0.0104
Onchocerca volvulus 0.0033 0.0142 0.0472
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.1582 0.1584
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.002 0.0057 0.0031
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0243 0.0243
Toxoplasma gondii C2 domain-containing protein 0.0033 0.0142 0.067
Echinococcus granulosus g-protein coupled receptor 0.0429 0.2888 0.2893
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0233 0.1531 0.1533
Entamoeba histolytica hypothetical protein, conserved 0.0033 0.0142 0.0644
Echinococcus granulosus copine 9 0.0033 0.0142 0.0142
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0033 0.0142 0.067
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0046 0.0046
Echinococcus granulosus UNCoordinated family member unc 13 0.0033 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus multilocularis NEDD4 E3 ubiquitin protein ligase WWP1 0.0033 0.0142 0.0142
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.4594 0.4594
Leishmania major hypothetical protein, conserved 0.0033 0.0142 0.2003
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Trichomonas vaginalis synaptotagmin 1, 3, C.elegans, putative 0.0033 0.0142 0.0853
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0165 0.1058 0.1058
Trichomonas vaginalis synaptotagmin, putative 0.0033 0.0142 0.0853
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.2888 0.2888
Plasmodium vivax ferlin, putative 0.0033 0.0142 0.1553
Echinococcus multilocularis GTP binding nuclear protein Ran 0.002 0.0054 0.0054
Brugia malayi G-protein coupled receptor 0.0429 0.2888 0.3422
Echinococcus multilocularis ornithine aminotransferase 0.002 0.0057 0.0057
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0034 0.015 0.015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0685 0.0685
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0042 0.0028
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0336 0.0336
Echinococcus granulosus cpg binding protein 0.003 0.0126 0.0126
Schistosoma mansoni hypothetical protein 0.0055 0.0297 0.0297
Echinococcus granulosus calpain 5 0.0033 0.0142 0.0142
Brugia malayi Dopamine receptor 0.0429 0.2888 0.3422
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0165 0.1058 0.1294
Schistosoma mansoni neuropeptide receptor 0.0429 0.2888 0.2888
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0053 0.0059
Leishmania major importin beta-1 subunit, putative 0.0022 0.0068 0.0921
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0104 0.0614
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Toxoplasma gondii hypothetical protein 0.0019 0.005 0.0059
Schistosoma mansoni copine 0.0033 0.0142 0.0142
Echinococcus granulosus neuropeptides capa receptor 0.0429 0.2888 0.2893
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0058 0.032 0.032
Brugia malayi Protein kinase c protein 2 0.1225 0.8404 1
Toxoplasma gondii GAF domain-containing protein 0.0019 0.005 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus granulosus protein kinase C gamma type 0.1288 0.8843 0.8857
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0143 0.0905 1
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0142 0.1553
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Echinococcus granulosus sex peptide receptor 0.0429 0.2888 0.2893
Loa Loa (eye worm) hypothetical protein 0.0197 0.1283 0.1571
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0034 0.015 0.015
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0019 0.005 0.0052
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Schistosoma mansoni synaptotagmin-like protein 0.0033 0.0142 0.0142
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.0685 0.1343
Trichomonas vaginalis synaptotagmin 1,2, putative 0.0033 0.0142 0.0853
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0142 0.2003
Loa Loa (eye worm) hypothetical protein 0.0165 0.1058 0.1294
Schistosoma mansoni growth hormone secretagogue receptor 0.0429 0.2888 0.2888
Schistosoma mansoni serine/threonine protein kinase 0.043 0.2898 0.2898
Loa Loa (eye worm) hypothetical protein 0.0379 0.2542 0.3118
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0107 0.0106
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0276 0.0333
Brugia malayi putative neuropeptide receptor NPR1 0.0429 0.2888 0.3422
Schistosoma mansoni opsin-like receptor 0.0429 0.2888 0.2888
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0338 0.4898
Loa Loa (eye worm) hypoxia-induced factor 1 0.0154 0.0983 0.1202
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0132 0.0132
Schistosoma mansoni protein kinase C 0.0197 0.1283 0.1283
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0233 0.1531 0.1533
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0336 0.4863
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0339 0.034
Echinococcus granulosus snurportin 1 0.0289 0.192 0.1923
Schistosoma mansoni cpg binding protein 0.0027 0.0103 0.0103
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0142 0.0863
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0016 0.0028 0.0144
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0061 0.0338 0.0339
Onchocerca volvulus 0.0033 0.0142 0.0472
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Schistosoma mansoni synaptotagmin 0.0033 0.0142 0.0142
Schistosoma mansoni rabphilin-3a 0.0033 0.0142 0.0142
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0338 0.2087
Leishmania major protein kinase, putative 0.0022 0.0066 0.0886
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0053 0.0053
Onchocerca volvulus 0.0429 0.2888 1
Brugia malayi hypothetical protein 0.0167 0.1073 0.1258
Echinococcus granulosus synaptotagmin protein 4 0.0033 0.0142 0.0142
Trypanosoma cruzi synaptotagmin, putative 0.0033 0.0142 0.2003
Brugia malayi Ras association domain family 1 isoform A 0.0165 0.1058 0.1239
Loa Loa (eye worm) hypothetical protein 0.0165 0.1058 0.1294
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Echinococcus multilocularis synaptotagmin 0.0033 0.0142 0.0142
Brugia malayi hypothetical protein 0.0034 0.015 0.0157
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0042 0.0533
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0033 0.0142 0.0142
Schistosoma mansoni neuropeptide receptor 0.0429 0.2888 0.2888
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0429 0.2888 0.2888
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.2888 0.2888
Toxoplasma gondii diacylglycerol kinase, putative 0.0165 0.1058 0.6823
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0046 0.0046
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.022 0.1347
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.022 0.1347
Onchocerca volvulus 0.0033 0.0142 0.0472
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0033 0.0142 0.0168
Entamoeba histolytica hypothetical protein 0.0034 0.015 0.0701
Echinococcus granulosus methyl CpG binding domain protein 2 0.0016 0.0027 0.0027
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.002 0.0057 0.0124
Leishmania major phospholipase c-like protein 0.0033 0.0142 0.2003
Echinococcus granulosus Protein kinase C brain isozyme 0.1453 0.9984 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0162 0.0193
Loa Loa (eye worm) hypothetical protein 0.0111 0.0685 0.0835
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.002 0.0057 0.0124
Echinococcus multilocularis copine 9 0.0033 0.0142 0.0142
Echinococcus multilocularis orexin receptor type 2 0.0429 0.2888 0.2893
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.083 0.5665 0.5674
Echinococcus multilocularis g protein coupled receptor 0.0429 0.2888 0.2893
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0061 0.0338 0.0338
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0165 0.1058 0.1294
Brugia malayi CXXC zinc finger family protein 0.0027 0.0103 0.0101
Brugia malayi Importin beta-1 subunit 0.0027 0.0104 0.0102
Leishmania major DNA polymerase eta, putative 0.002 0.0053 0.0695
Echinococcus multilocularis importin subunit beta 1 0.0027 0.0104 0.0104
Echinococcus granulosus active breakpoint cluster region 0.0033 0.0142 0.0142
Echinococcus multilocularis neuropeptide Y receptor 0.0429 0.2888 0.2893
Onchocerca volvulus 0.0075 0.0432 0.148
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0871 0.0872
Echinococcus granulosus synaptotagmin 0.0033 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0111 0.0685 0.0835
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Plasmodium vivax SET domain protein, putative 0.0031 0.0132 0.1399
Entamoeba histolytica protein kinase, putative 0.0233 0.1531 1
Echinococcus granulosus single minded 2 0.0037 0.0171 0.0171
Schistosoma mansoni rho gtpase activating protein 0.0033 0.0142 0.0142
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.002 0.0054 0.0599
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Toxoplasma gondii hypothetical protein 0.0019 0.005 0.0059
Loa Loa (eye worm) hypothetical protein 0.0028 0.0107 0.0126
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0102 0.01
Echinococcus multilocularis musashi 0.0028 0.0107 0.0107
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0033 0.0142 0.0142
Echinococcus granulosus neuropeptide receptor 0.0429 0.2888 0.2893
Echinococcus granulosus neuropeptides capa receptor 0.0429 0.2888 0.2893
Echinococcus multilocularis 0.0033 0.0142 0.0142
Echinococcus multilocularis G-protein coupled receptor, putative 0.0429 0.2888 0.2893
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Echinococcus multilocularis C2 calcium lipid binding region, CaLB 0.0033 0.0142 0.0142
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0197 0.1283 0.1285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.2888 0.2888
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0033 0.0142 0.0142
Entamoeba histolytica C2 domain containing protein 0.0033 0.0142 0.0644
Echinococcus multilocularis g-protein coupled receptor 0.0429 0.2888 0.2893
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0429 0.2888 0.3542
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0429 0.2888 0.3422
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0429 0.2888 0.2888
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0046 0.0595
Schistosoma mansoni neuropeptide f receptor 76f 0.0429 0.2888 0.2888
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Leishmania major hypothetical protein, conserved 0.0027 0.0103 0.1442
Leishmania major hypothetical protein, conserved 0.0033 0.0142 0.2003
Echinococcus granulosus microtubule associated protein 2 0.0675 0.4594 0.4601
Echinococcus granulosus orexin receptor type 2 0.0429 0.2888 0.2893
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0102 0.0607
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Loa Loa (eye worm) hypothetical protein 0.0027 0.0104 0.0122
Brugia malayi G protein-coupled receptor F59B2.13 0.0429 0.2888 0.3422
Loa Loa (eye worm) neuropeptide F receptor 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.0685 0.1343
Onchocerca volvulus 0.0197 0.1283 0.4432
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0162 0.0171
Echinococcus granulosus multiple C2 and transmembrane domain containing protein 0.0033 0.0142 0.0142
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0165 0.1058 0.1058
Plasmodium falciparum ornithine aminotransferase 0.002 0.0057 0.1068
Schistosoma mansoni serine/threonine protein kinase 0.1453 0.9984 0.9984
Entamoeba histolytica hypothetical protein 0.0033 0.0142 0.0644
Trichomonas vaginalis esterase, putative 0.0111 0.0685 0.4261
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0046 0.0051
Entamoeba histolytica diacylglycerol kinase, putative 0.0165 0.1058 0.6814
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0033 0.0142 0.2003
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0042 0.0533
Schistosoma mansoni phosphoglucomutase 0.0027 0.0101 0.0101
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.002 0.0054 0.0288
Echinococcus multilocularis neuropeptide receptor 0.0429 0.2888 0.2893
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0132 0.0132
Schistosoma mansoni serine/threonine kinase 0.0233 0.1531 0.1531
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0429 0.2888 0.2888
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0111 0.0685 0.0835
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.002 0.0057 0.0031
Onchocerca volvulus 0.0429 0.2888 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0429 0.2888 0.2893
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.005 0.0056
Mycobacterium ulcerans hypothetical protein 0.0111 0.0685 0.7431
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0046 0.0595
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.0685 0.1343
Loa Loa (eye worm) hypothetical protein 0.0027 0.0104 0.0122
Brugia malayi Copine family protein 0.0033 0.0142 0.0147
Echinococcus granulosus serotonin receptor 0.0429 0.2888 0.2893
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0336 0.3372
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0046 0.0009
Plasmodium falciparum ferlin, putative 0.0033 0.0142 0.7177
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0429 0.2888 0.3422
Entamoeba histolytica hypothetical protein, conserved 0.0033 0.0142 0.0644
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0053 0.0041
Schistosoma mansoni hypothetical protein 0.0019 0.005 0.005
Echinococcus multilocularis adenylate cyclase 9 0.0078 0.0455 0.0456
Trypanosoma brucei ISWI complex protein 0.0014 0.0015 0.0034
Brugia malayi RNase H family protein 0.0027 0.0101 0.0098
Echinococcus granulosus otoferlin 0.0033 0.0142 0.0142
Onchocerca volvulus 0.0429 0.2888 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0338 0.2087
Schistosoma mansoni zinc finger protein 0.0023 0.0078 0.0078
Onchocerca volvulus 0.0429 0.2888 1
Loa Loa (eye worm) AGC/AKT protein kinase 0.0233 0.1531 0.1875
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0336 0.3372
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0165 0.1058 0.1294
Brugia malayi Synaptotagmin I 0.0033 0.0142 0.0147
Brugia malayi Protein kinase domain containing protein 0.0233 0.1531 0.1803
Schistosoma mansoni single-minded 0.005 0.0261 0.0261
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0142 0.0863
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0053 0.0279
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Loa Loa (eye worm) hypothetical protein 0.0165 0.1058 0.1294
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Schistosoma mansoni hypothetical protein 0.0016 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0165 0.1058 0.1294
Entamoeba histolytica hypothetical protein 0.0034 0.015 0.0701
Entamoeba histolytica Ran family GTPase 0.002 0.0054 0.0054
Entamoeba histolytica C2 domain containing protein 0.0033 0.0142 0.0644
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0053 0.0053
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.0033 0.0142 0.0142
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0233 0.1531 0.1533
Trypanosoma cruzi cytoskeleton associated protein, putative 0.0033 0.0142 0.2003
Trypanosoma brucei C2 domain/Ankyrin repeats (3 copies), putative 0.0033 0.0142 0.0863
Loa Loa (eye worm) hypothetical protein 0.0027 0.0102 0.012
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0338 0.2087
Brugia malayi hypothetical protein 0.027 0.1786 0.2108
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.022 0.1199
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Brugia malayi ORL1-like opioid receptor 0.0429 0.2888 0.3422
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.004 0.0513
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.2888 0.2888
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0142 0.2003
Entamoeba histolytica hypothetical protein 0.0165 0.1058 0.6814
Schistosoma mansoni phosphoglucomutase 0.0027 0.0101 0.0101
Loa Loa (eye worm) raf kinase 0.0165 0.1058 0.1294
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.002 0.0057 0.0124
Entamoeba histolytica C2 domain containing protein 0.0033 0.0142 0.0644
Schistosoma mansoni survival motor neuron protein 0.0055 0.0297 0.0297
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0429 0.2888 0.2888
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0103 0.096
Echinococcus granulosus 7tm_1 domain containing protein 0.0429 0.2888 0.2893
Echinococcus multilocularis neuropeptide Y receptor 0.0429 0.2888 0.2893
Schistosoma mansoni alpha-1 adrenergic receptor 0.0429 0.2888 0.2888
Trypanosoma cruzi ISWI complex protein 0.0014 0.0015 0.0146
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0033 0.0142 0.0142
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0103 0.0415
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0685 0.4261
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Mycobacterium ulcerans acetylornithine aminotransferase 0.002 0.0057 0.0124
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Echinococcus multilocularis neuropeptides capa receptor 0.0429 0.2888 0.2893
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0028 0.0144
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0685 1
Entamoeba histolytica protein kinase, putative 0.0233 0.1531 1
Brugia malayi diacylglycerol kinase 0.0165 0.1058 0.1239
Schistosoma mansoni biogenic amine receptor 0.0429 0.2888 0.2888
Onchocerca volvulus 0.0028 0.0107 0.0352
Onchocerca volvulus 0.0243 0.1599 0.553
Brugia malayi N-terminal motif family protein 0.017 0.1091 0.1279
Schistosoma mansoni cpg binding protein 0.003 0.0126 0.0126
Onchocerca volvulus 0.0031 0.0132 0.0437
Trichomonas vaginalis synaptotagmin, putative 0.0033 0.0142 0.0853
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Schistosoma mansoni lamin 0.0028 0.0107 0.0107
Trichomonas vaginalis annexin VII, putative 0.0033 0.0142 0.0853
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0033 0.0142 0.0142
Echinococcus multilocularis g protein coupled receptor 0.0429 0.2888 0.2893
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus multilocularis Diacylglycerol kinase theta 0.0165 0.1058 0.1059
Loa Loa (eye worm) hypothetical protein 0.0047 0.0243 0.0292
Echinococcus multilocularis protein kinase c eta type 0.0165 0.1058 0.1059
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0685 0.4261
Onchocerca volvulus 0.0429 0.2888 1
Schistosoma mansoni ap endonuclease 0.0019 0.0046 0.0046
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0006 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Echinococcus granulosus G protein coupled receptor 139 0.0429 0.2888 0.2893
Mycobacterium tuberculosis Conserved protein 0.0111 0.0685 0.1343
Echinococcus granulosus intersectin 2 0.0033 0.0142 0.0142
Toxoplasma gondii hypothetical protein 0.0033 0.0142 0.067
Brugia malayi PHD-finger family protein 0.0028 0.0113 0.0113
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.002 0.0057 0.0031
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0143 0.0905 1
Schistosoma mansoni neuropeptide F-like receptor 0.0429 0.2888 0.2888
Echinococcus multilocularis calpain 5 0.0033 0.0142 0.0142
Echinococcus granulosus biogenic amine 5HT receptor 0.0429 0.2888 0.2893
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0054 0.0714
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0914 0.0915
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0339 0.034
Toxoplasma gondii ferlin family protein 0.0033 0.0142 0.067
Loa Loa (eye worm) hypothetical protein 0.002 0.0053 0.0059
Echinococcus multilocularis serotonin receptor 0.0429 0.2888 0.2893
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Echinococcus granulosus multiple C2 and transmembrane domain containing protein 0.0033 0.0142 0.0142
Leishmania major hypothetical protein, conserved 0.0033 0.0142 0.2003
Mycobacterium tuberculosis Conserved protein 0.0111 0.0685 0.1343
Schistosoma mansoni protein kinase C mu 0.0165 0.1058 0.1058
Echinococcus multilocularis lamin dm0 0.0028 0.0107 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.1531 0.1531
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0338 0.2087
Onchocerca volvulus 0.0033 0.0142 0.0472
Echinococcus granulosus neuropeptide FF receptor 2 0.0429 0.2888 0.2893
Onchocerca volvulus 0.0429 0.2888 1
Entamoeba histolytica C2 domain protein, putative 0.0033 0.0142 0.0644
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0429 0.2888 0.2893
Loa Loa (eye worm) hypothetical protein 0.0016 0.003 0.0031
Trichomonas vaginalis synaptotagmin, putative 0.0033 0.0142 0.0853
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0914 0.1068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.2888 0.2888
Echinococcus multilocularis unc 13 (munc13) 0.0197 0.1283 0.1285
Plasmodium falciparum ferlin, putative 0.0033 0.0142 0.7177
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0033 0.0142 0.0142
Echinococcus multilocularis synaptotagmin 0.0033 0.0142 0.0142
Leishmania major ribonuclease H1, putative 0.0027 0.0101 0.1401
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0286 0.1761
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.017 0.1092 0.1094
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0429 0.2888 0.2893
Brugia malayi Pre-SET motif family protein 0.0214 0.1396 0.1642
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0029 0.0116 0.0698
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0338 0.2087
Trichomonas vaginalis synaptotagmin, putative 0.0033 0.0142 0.0853
Echinococcus granulosus RNA directed DNA polymerase 0.1025 0.7018 0.7029
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0042 0.0204 0.2917
Echinococcus multilocularis serine:threonine protein kinase N2 0.0233 0.1531 0.1533
Mycobacterium ulcerans putative regulatory protein 0.0019 0.005 0.0052
Echinococcus granulosus ornithine aminotransferase 0.002 0.0057 0.0057
Echinococcus granulosus neuropeptide Y receptor 0.0429 0.2888 0.2893
Trypanosoma brucei synaptotagmin, putative 0.0033 0.0142 0.0863
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0046 0.0066
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0107 0.0126
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0116 0.0698
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0336 0.0615
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0297 0.0333
Leishmania major hypothetical protein, conserved 0.0111 0.0685 1
Echinococcus granulosus allatostatin A receptor 0.0429 0.2888 0.2893
Trichomonas vaginalis copine, putative 0.0033 0.0142 0.0853
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0142 0.2003
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0027 0.0027
Trypanosoma cruzi ribonuclease H1, putative 0.0027 0.0101 0.1401
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0018 0.0017
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0233 0.1531 0.1533
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0028 0.0144
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0033 0.0142 0.0142
Echinococcus granulosus alpha 1A adrenergic receptor 0.0429 0.2888 0.2893
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0033 0.0142 0.0863
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0008 0.0008
Brugia malayi diacylglycerol kinase 0.0165 0.1058 0.1239
Echinococcus granulosus Rac GTPase activating protein 1 0.0165 0.1058 0.1059
Entamoeba histolytica protein kinase, putative 0.0038 0.0176 0.0878
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.1396 0.1709
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0429 0.2888 0.2893
Echinococcus granulosus synaptotagmin 0.0033 0.0142 0.0142
Echinococcus granulosus serine:threonine protein kinase N2 0.0233 0.1531 0.1533
Brugia malayi beta-lactamase family protein 0.0111 0.0685 0.0795
Trichomonas vaginalis synaptotagmin 1, 3, C.elegans, putative 0.0033 0.0142 0.0853
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0042 0.0042
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0165 0.1058 0.1059
Schistosoma mansoni lamin 0.0028 0.0107 0.0107
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0338 0.2087
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0102 0.0607
Brugia malayi Serotonin receptor 0.0429 0.2888 0.3422
Trichomonas vaginalis vab10 spectraplakin, putative 0.0033 0.0142 0.0853
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0429 0.2888 0.3422
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus multilocularis Protein kinase C, brain isozyme 0.1453 0.9984 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0429 0.2888 0.2893
Trypanosoma brucei rac serine-threonine kinase, putative 0.0233 0.1531 1
Trichomonas vaginalis importin beta-1, putative 0.0022 0.0068 0.0392
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0046 0.0235
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Schistosoma mansoni atypical protein kinase C 0.0398 0.2672 0.2672
Schistosoma mansoni hypothetical protein 0.0014 0.0015 0.0015
Echinococcus multilocularis RNA directed DNA polymerase 0.1025 0.7018 0.7029
Loa Loa (eye worm) hypothetical protein 0.0165 0.1058 0.1294
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0006 0.0006
Schistosoma mansoni opsin-like receptor 0.0429 0.2888 0.2888
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0181 1
Schistosoma mansoni hypothetical protein 0.0033 0.0142 0.0142
Entamoeba histolytica C2 domain containing protein 0.0033 0.0142 0.0644
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.0685 0.0795
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0053 0.0053
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0053 0.0023
Echinococcus granulosus raf serine:threonine protein kinase 0.0165 0.1058 0.1059
Brugia malayi beta-lactamase family protein 0.0111 0.0685 0.0795
Onchocerca volvulus 0.0027 0.0103 0.0337
Echinococcus granulosus dna polymerase eta 0.002 0.0053 0.0053
Mycobacterium leprae conserved hypothetical protein 0.0111 0.0685 0.7547
Loa Loa (eye worm) RasGEF domain-containing protein 0.0167 0.1071 0.1311
Echinococcus multilocularis lamin 0.0028 0.0107 0.0107
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0027 0.0101 1
Echinococcus granulosus GPCR family 2 0.0016 0.003 0.003
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0033 0.0142 0.0853
Mycobacterium ulcerans L-lysine aminotransferase 0.002 0.0057 0.0124
Onchocerca volvulus 0.0111 0.0685 0.2356
Echinococcus granulosus survival motor neuron protein 1 0.027 0.1786 0.1789
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Trypanosoma brucei cAMP binding protein, putative 0.0036 0.0167 0.103
Echinococcus multilocularis ribonuclease H1 0.0027 0.0101 0.0101
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Echinococcus multilocularis neuropeptides capa receptor 0.0429 0.2888 0.2893
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0033 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.1187 0.8144 1
Brugia malayi RNase H family protein 0.0027 0.0101 0.0098
Schistosoma mansoni zinc finger protein 0.0014 0.0015 0.0015
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Entamoeba histolytica protein kinase, putative 0.0233 0.1531 1
Schistosoma mansoni amine GPCR 0.0429 0.2888 0.2888
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.0685 0.7431
Trichomonas vaginalis calcium-dependent lipid-binding protein, putative 0.0033 0.0142 0.0853
Brugia malayi Protein kinase domain containing protein 0.0233 0.1531 0.1803
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0053 0.0296
Brugia malayi C1-like domain containing protein 0.017 0.1092 0.1281
Echinococcus granulosus synaptotagmin 0.0033 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Brugia malayi G protein-coupled receptor 0.0429 0.2888 0.3422
Echinococcus multilocularis UNCoordinated family member (unc 13) 0.0033 0.0142 0.0142
Onchocerca volvulus 0.0037 0.0171 0.0575
Toxoplasma gondii Elicitor-responsive protein, putative 0.0033 0.0142 0.067
Onchocerca volvulus 0.0055 0.0297 0.1013
Mycobacterium ulcerans beta-lactamase 0.0111 0.0685 0.7431
Echinococcus granulosus ribonuclease H1 0.0027 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Toxoplasma gondii hypothetical protein 0.0033 0.0142 0.067
Brugia malayi Serotonin receptor 0.0429 0.2888 0.3422
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0053 0.0053
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0053 0.0695
Echinococcus granulosus myoferlin 0.0033 0.0142 0.0142
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.022 0.0221
Echinococcus multilocularis g protein coupled receptor 0.0429 0.2888 0.2893
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Mycobacterium leprae Probable lipase LipE 0.0111 0.0685 0.7547
Echinococcus multilocularis dna polymerase kappa 0.002 0.0053 0.0053
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0061 0.0338 0.2157
Loa Loa (eye worm) C2 domain-containing protein 0.0033 0.0142 0.0168
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.2888 0.2888
Schistosoma mansoni mctp-related 0.0033 0.0142 0.0142
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0068 0.0392
Loa Loa (eye worm) adenylyl cyclase 3 0.0184 0.119 0.1456
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.0685 0.0686
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Trypanosoma cruzi importin beta-1 subunit, putative 0.0022 0.0068 0.0921
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0429 0.2888 0.2888
Toxoplasma gondii ABC1 family protein 0.0111 0.0685 0.4318
Echinococcus granulosus somatostatin receptor 0.0429 0.2888 0.2893
Onchocerca volvulus 0.0028 0.0107 0.0352
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.005 0.0627
Schistosoma mansoni hypothetical protein 0.0165 0.1058 0.1058
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Loa Loa (eye worm) acetyltransferase 0.0144 0.0914 0.1117
Onchocerca volvulus 0.0111 0.0685 0.2356
Loa Loa (eye worm) TYRA-2 protein 0.0429 0.2888 0.3542
Schistosoma mansoni hypothetical protein 0.0429 0.2888 0.2888
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Entamoeba histolytica Rap/Ran GTPase activating protein, putative 0.0033 0.0142 0.0644
Trypanosoma brucei RNA helicase, putative 0.01 0.0609 0.3937
Trichomonas vaginalis synaptotagmin 1,2, putative 0.0033 0.0142 0.0853
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.0685 0.1343
Schistosoma mansoni protein kinase C mu 0.017 0.1092 0.1092
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.003 0.0031
Trypanosoma brucei ribonuclease H1 0.0027 0.0101 0.0595
Trypanosoma cruzi C2 domain containing protein, putative 0.0033 0.0142 0.2003
Entamoeba histolytica protein kinase, putative 0.0233 0.1531 1
Schistosoma mansoni hypothetical protein 0.0033 0.0142 0.0142
Echinococcus granulosus myotubularin protein 13 0.0165 0.1058 0.1059
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0019 0.005 0.0018
Echinococcus multilocularis GPCR, family 2 0.0016 0.003 0.003
Brugia malayi Dopamine receptor protein 2 0.0429 0.2888 0.3422
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0429 0.2888 0.3542
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0429 0.2888 0.2893
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0243 0.0243
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0429 0.2888 0.2893
Loa Loa (eye worm) C2 domain-containing protein 0.0033 0.0142 0.0168
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.003 0.003
Echinococcus multilocularis neuropeptide s receptor 0.0429 0.2888 0.2893
Echinococcus granulosus dro:myosuppressin receptor 0.0429 0.2888 0.2893
Mycobacterium ulcerans lipase LipD 0.0111 0.0685 0.7431
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0429 0.2888 0.2893
Echinococcus granulosus NEDD4 E3 ubiquitin protein ligase WWP1 0.0033 0.0142 0.0142
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0429 0.2888 0.2893
Echinococcus multilocularis neuropeptide receptor 0.0429 0.2888 0.2893
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.003 0.0014
Plasmodium falciparum double C2-like domain-containing protein 0.0033 0.0142 0.7177
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0233 0.1531 0.1533
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0053 0.0695
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0429 0.2888 0.2888
Loa Loa (eye worm) hypothetical protein 0.0111 0.0685 0.0835
Echinococcus granulosus biogenic amine 5HT receptor 0.0429 0.2888 0.2893
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.0102 0.0102
Echinococcus multilocularis myoferlin 0.0033 0.0142 0.0142
Echinococcus granulosus adenylate cyclase type IX 0.0109 0.0674 0.0675
Brugia malayi sulfakinin receptor protein 0.0429 0.2888 0.3422
Schistosoma mansoni synaptotagmin 0.0033 0.0142 0.0142
Loa Loa (eye worm) AGC/NDR protein kinase 0.0233 0.1531 0.1875
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0429 0.2888 0.2888
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0143 0.0905 0.1805
Trypanosoma cruzi Coiled-coil and C2 domain-containing protein 0.0033 0.0142 0.2003
Echinococcus multilocularis dna polymerase eta 0.002 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Plasmodium vivax hypothetical protein, conserved 0.0111 0.0685 1
Schistosoma mansoni bromodomain containing protein 0.0064 0.0362 0.0362
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0046 0.0254
Echinococcus multilocularis serine threonine protein kinase 0.1288 0.8843 0.8857
Echinococcus multilocularis neuropeptide FF receptor 2 0.0429 0.2888 0.2893
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.017 0.1092 0.1092
Loa Loa (eye worm) hypothetical protein 0.0146 0.0928 0.1134
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Echinococcus granulosus adenylate cyclase 9 0.0078 0.0455 0.0456
Schistosoma mansoni nedd-4-like E3 ubiquitin-protein ligase 0.0033 0.0142 0.0142
Echinococcus multilocularis intersectin 2 0.0033 0.0142 0.0142
Mycobacterium leprae conserved hypothetical protein 0.0019 0.005 0.0499
Echinococcus granulosus Immunoglobulin E set 0.0033 0.0142 0.0142
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0338 0.4898
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.002 0.0057 0.0031
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0143 0.0905 0.5646
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0317 0.185
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.0075 0.0432 0.0525
Loa Loa (eye worm) melatonin receptor type 1A 0.0429 0.2888 0.3542
Schistosoma mansoni hypothetical protein 0.0173 0.1117 0.1117
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0142 0.2003
Brugia malayi Bromodomain containing protein 0.0075 0.0439 0.0501
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0027 0.0102 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Trichomonas vaginalis synaptotagmin, putative 0.0033 0.0142 0.0853
Echinococcus granulosus protein kinase c epsilon type 0.043 0.2898 0.2902
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0033 0.0142 0.0168
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0429 0.2888 0.2888
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0228 0.1496 0.935
Echinococcus granulosus synaptotagmin 0.0033 0.0142 0.0142
Schistosoma mansoni amine GPCR 0.0429 0.2888 0.2888
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0233 0.1531 0.1875
Onchocerca volvulus 0.0429 0.2888 1
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Onchocerca volvulus 0.0165 0.1058 0.365
Echinococcus multilocularis multiple C2 and transmembrane domain containing protein 0.0033 0.0142 0.0142
Echinococcus granulosus neuropeptide s receptor 0.0429 0.2888 0.2893
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0429 0.2888 0.2893
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.1582 0.1584
Schistosoma mansoni hypothetical protein 0.0173 0.1117 0.1117
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0042 0.0533
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0042 0.0042
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0033 0.0142 0.0142
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0053 0.0041
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0073 0.0073
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0429 0.2888 0.2893
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0104 0.0614
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0429 0.2888 0.3542
Schistosoma mansoni unc-13 (munc13) 0.0033 0.0142 0.0142
Giardia lamblia Ribonuclease H 0.0027 0.0101 0.4059
Schistosoma mansoni adenoreceptor 0.0429 0.2888 0.2888
Schistosoma mansoni transcription factor LCR-F1 0.0034 0.015 0.015
Onchocerca volvulus 0.0429 0.2888 1
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0053 0.0279
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Schistosoma mansoni biogenic amine receptor 0.0429 0.2888 0.2888
Schistosoma mansoni Mername-AA248 (C02 family) 0.0033 0.0142 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0102 0.0607
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0142 0.0147
Echinococcus granulosus tachykinin peptides receptor 99D 0.0429 0.2888 0.2893
Brugia malayi RNase H family protein 0.0027 0.0101 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.1531 0.1531
Entamoeba histolytica hypothetical protein 0.0034 0.015 0.0701
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0338 0.2087
Onchocerca volvulus 0.0111 0.0685 0.2356
Brugia malayi RNA, U transporter 1 0.0077 0.045 0.0514
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0338 0.2087
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0042 0.0042
Schistosoma mansoni glut4 vesicle protein-related 0.0033 0.0142 0.0142
Entamoeba histolytica hypothetical protein 0.0033 0.0142 0.0644
Echinococcus granulosus hypothetical protein 0.0429 0.2888 0.2893
Entamoeba histolytica hypothetical protein 0.0034 0.015 0.0701
Loa Loa (eye worm) hypothetical protein 0.0036 0.0166 0.0198
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0336 0.0336
Schistosoma mansoni hypothetical protein 0.01 0.0609 0.0609
Echinococcus multilocularis neural cell expressed, developmentally 0.0033 0.0142 0.0142
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0034 0.015 0.015
Schistosoma mansoni hypothetical protein 0.0289 0.192 0.192
Echinococcus multilocularis protein kinase c iota type 0.0398 0.2672 0.2676
Echinococcus granulosus C2 calcium lipid binding region CaLB 0.0033 0.0142 0.0142
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Onchocerca volvulus 0.0165 0.1058 0.365
Giardia lamblia DINP protein human, muc B family 0.002 0.0053 0.0503
Echinococcus multilocularis neuropeptide receptor A26 0.0429 0.2888 0.2893
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0053 0.0279
Brugia malayi G-protein coupled receptor 0.0429 0.2888 0.3422
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0033 0.0142 0.0142
Echinococcus granulosus synaptotagmin 15 0.0033 0.0142 0.0142
Brugia malayi Protein kinase domain containing protein 0.017 0.1092 0.1281
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0685 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Schistosoma mansoni serine/threonine protein kinase 0.017 0.1092 0.1092
Loa Loa (eye worm) hypothetical protein 0.0111 0.0685 0.0835
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0046 0.0305
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Echinococcus multilocularis somatostatin receptor 0.0429 0.2888 0.2893
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0181 0.0908
Trichomonas vaginalis copine, putative 0.0033 0.0142 0.0853
Trichomonas vaginalis Circumsporozoite protein precursor, putative 0.0033 0.0142 0.0853
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0016 0.0027 0.0027
Trichomonas vaginalis synaptotagmin, putative 0.0033 0.0142 0.0853
Echinococcus multilocularis Aminotransferase class III 0.002 0.0057 0.0057
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0429 0.2888 0.2893
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0027 0.0102 0.0102
Toxoplasma gondii ribonuclease HI protein 0.0027 0.0101 0.0396
Loa Loa (eye worm) beta-lactamase 0.0111 0.0685 0.0835
Schistosoma mansoni importin beta-1 0.0027 0.0104 0.0104
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0028 0.0144
Schistosoma mansoni hypothetical protein 0.0016 0.003 0.003
Echinococcus granulosus tm gpcr rhodopsin 0.0429 0.2888 0.2893
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0042 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Echinococcus multilocularis myotubularin protein 13 0.0165 0.1058 0.1059
Loa Loa (eye worm) hypothetical protein 0.0042 0.0205 0.0246
Echinococcus granulosus copine 9 0.0033 0.0142 0.0142
Trypanosoma cruzi C2 domain/Ankyrin repeats (3 copies), putative 0.0033 0.0142 0.2003
Echinococcus multilocularis N chimaerin 0.0165 0.1058 0.1059
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Mycobacterium ulcerans hypothetical protein 0.0143 0.0905 1
Schistosoma mansoni histamine h1 receptor 0.0429 0.2888 0.2888
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus multilocularis protein kinase c epsilon type 0.043 0.2898 0.2902
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.017 0.1092 0.1094
Echinococcus granulosus unc 13 munc13 0.0197 0.1283 0.1285
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.0685 0.1343
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.024 0.1582 0.1864
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.002 0.0054 0.0043
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.002 0.0057 0.0567
Brugia malayi p70 ribosomal S6 kinase beta 0.0233 0.1531 0.1803
Loa Loa (eye worm) copine family protein 0.0033 0.0142 0.0168
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0276 0.0307
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0027 0.0027
Entamoeba histolytica C2 domain containing protein 0.0033 0.0142 0.0644
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.003 0.003
Leishmania major DNA polymerase kappa, putative 0.002 0.0053 0.0695
Echinococcus multilocularis multiple C2 and transmembrane domain containing protein 0.0033 0.0142 0.0142
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0181 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0429 0.2888 0.2893
Trichomonas vaginalis copine, putative 0.0033 0.0142 0.0853
Trypanosoma brucei ingi protein (ORF1) 0.0029 0.0116 0.0698
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Brugia malayi PAS domain containing protein 0.005 0.0261 0.0289
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0142 0.2003
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0033 0.0142 0.0168
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Loa Loa (eye worm) hypothetical protein 0.0066 0.0376 0.0456
Echinococcus granulosus protein kinase c iota type 0.0398 0.2672 0.2676
Mycobacterium ulcerans putative regulatory protein 0.0019 0.005 0.0052
Schistosoma mansoni fer-1-related 0.0033 0.0142 0.0142
Schistosoma mansoni unc-13 (munc13) 0.0197 0.1283 0.1283
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0233 0.1531 0.1875
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0286 0.1761
Echinococcus multilocularis copine 9 0.0033 0.0142 0.0142
Echinococcus granulosus GTP binding nuclear protein Ran 0.002 0.0054 0.0054
Trichomonas vaginalis Proline-rich protein, putative 0.0033 0.0142 0.0853
Echinococcus multilocularis synaptotagmin 2 0.0033 0.0142 0.0142
Loa Loa (eye worm) CAMK/PKD protein kinase 0.017 0.1092 0.1336
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Echinococcus multilocularis allatostatin A receptor 0.0429 0.2888 0.2893
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.0685 0.7431
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.0685 0.0835
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Echinococcus granulosus g protein coupled receptor 0.0429 0.2888 0.2893
Entamoeba histolytica calcium-binding protein, putative 0.0033 0.0142 0.0644
Schistosoma mansoni hypothetical protein 0.0429 0.2888 0.2888
Entamoeba histolytica hypothetical protein 0.0033 0.0142 0.0644
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0061 0.0338 0.2157
Echinococcus multilocularis synaptotagmin 15 0.0033 0.0142 0.0142
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0028 0.0144
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.017 0.1092 0.1281
Brugia malayi RhoGEF domain containing protein 0.0165 0.1058 0.1239
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0103 0.4438
Brugia malayi Tachykinin-like peptides receptor 99D 0.0429 0.2888 0.3422
Echinococcus multilocularis geminin 0.0173 0.1117 0.1119
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0429 0.2888 0.2888
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0165 0.1058 0.1294
Onchocerca volvulus 0.0429 0.2888 1
Echinococcus multilocularis fmrfamide receptor 0.0429 0.2888 0.2893
Schistosoma mansoni unc-13 (munc13) 0.02 0.1298 0.1298
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0165 0.1058 0.1294
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.1582 0.1582
Brugia malayi calpain 5 0.0033 0.0142 0.0147
Trypanosoma cruzi cytoskeleton associated protein, putative 0.0033 0.0142 0.2003
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0142 0.2003
Trichomonas vaginalis splicing factor 3A subunit, putative 0.0033 0.0142 0.0853
Brugia malayi larval opioid receptor 0.0429 0.2888 0.3422
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0709 0.4827 1
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0033 0.0142 0.0142
Onchocerca volvulus 0.0429 0.2888 1
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0046 0.0254
Schistosoma mansoni amine GPCR 0.0429 0.2888 0.2888
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.4594 0.4601
Loa Loa (eye worm) AGC/PKN protein kinase 0.0233 0.1531 0.1875
Echinococcus granulosus geminin 0.0173 0.1117 0.1119
Loa Loa (eye worm) hypothetical protein 0.027 0.1786 0.2189
Trypanosoma brucei unspecified product 0.002 0.0053 0.0279
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0053 0.0079
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0061 0.0338 0.2087
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0429 0.2888 0.2888
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0338 0.4898
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.005 0.0282
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Brugia malayi beta-lactamase 0.0111 0.0685 0.0795
Brugia malayi Protein kinase domain containing protein 0.0233 0.1531 0.1803
Echinococcus granulosus neuropeptide receptor A26 0.0429 0.2888 0.2893
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.0104 0.0416
Brugia malayi NEDD4.2 0.0033 0.0142 0.0147
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.004 0.0513
Entamoeba histolytica hypothetical protein 0.0033 0.0142 0.0644
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0276 0.0307
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.0685 0.1343
Schistosoma mansoni DNA polymerase eta 0.002 0.0053 0.0053
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0429 0.2888 0.2888
Trypanosoma brucei C2 domain containing protein, putative 0.0033 0.0142 0.0863
Echinococcus granulosus Solute carrier family 22 5 0.1035 0.7091 0.7102
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.002 0.0057 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0053 0.0695
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0429 0.2888 0.2888
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.2888 0.2888
Brugia malayi RE15519p 0.0429 0.2888 0.3422
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0006 0.0006
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.017 0.1091 0.3766
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0061 0.0338 0.0339
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0033 0.0142 0.0147
Trichomonas vaginalis set domain proteins, putative 0.0243 0.1599 1
Echinococcus multilocularis G protein coupled receptor 139 0.0429 0.2888 0.2893
Echinococcus multilocularis snurportin 1 0.0289 0.192 0.1923
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.002 0.0057 0.01
Entamoeba histolytica C2 domain containing protein 0.0033 0.0142 0.0644
Brugia malayi neuropeptide F receptor 0.0429 0.2888 0.3422
Echinococcus multilocularis active breakpoint cluster region 0.0033 0.0142 0.0142
Trichomonas vaginalis copine, putative 0.0033 0.0142 0.0853
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Schistosoma mansoni phosphoglucomutase 0.0027 0.0101 0.0101
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0061 0.0338 0.2087
Schistosoma mansoni hypothetical protein 0.0429 0.2888 0.2888
Loa Loa (eye worm) G-protein coupled receptor 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.017 0.1091 0.1335
Echinococcus granulosus tm gpcr rhodopsin 0.0429 0.2888 0.2893
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0103 0.4438
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.017 0.1092 0.1336
Schistosoma mansoni synaptotagmin 0.0033 0.0142 0.0142
Entamoeba histolytica C2 domain containing protein 0.0033 0.0142 0.0644
Onchocerca volvulus Neuropeptide F receptor homolog 0.0429 0.2888 1
Entamoeba histolytica hypothetical protein 0.0033 0.0142 0.0644
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.004 0.0513
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0103 0.1442
Echinococcus multilocularis sex peptide receptor 0.0429 0.2888 0.2893
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.043 0.2898 0.3555
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Schistosoma mansoni synaptotagmin 12 0.0033 0.0142 0.0142
Trypanosoma brucei unspecified product 0.0029 0.0116 0.0698
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0132 0.0604
Loa Loa (eye worm) C2 domain-containing protein 0.0033 0.0142 0.0168
Trichomonas vaginalis ion channel nompc, putative 0.0033 0.0142 0.0853
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0429 0.2888 0.2893
Trypanosoma brucei C2 domain containing protein, putative 0.0033 0.0142 0.0863
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.1531 0.1531
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.106 0.7263 0.8917
Echinococcus multilocularis serotonin receptor 0.0429 0.2888 0.2893
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Loa Loa (eye worm) CXXC zinc finger family protein 0.0027 0.0103 0.012
Schistosoma mansoni otoferlin 0.0033 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.002 0.0054 0.0192
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0042 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Loa Loa (eye worm) hypothetical protein 0.0052 0.0276 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0286 0.1761
Echinococcus granulosus N chimaerin 0.0165 0.1058 0.1059
Echinococcus granulosus g protein coupled receptor 0.0429 0.2888 0.2893
Echinococcus multilocularis synaptotagmin 0.0033 0.0142 0.0142
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0429 0.2888 0.3422
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0685 0.0685
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0429 0.2888 0.3542
Schistosoma mansoni hypothetical protein 0.0033 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Trypanosoma brucei predicted C2 domain protein 0.0033 0.0142 0.0863
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.012 0.012
Echinococcus granulosus Aminotransferase class III 0.002 0.0057 0.0057
Schistosoma mansoni cpg binding protein 0.003 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus multilocularis cpg binding protein 0.003 0.0126 0.0126
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0429 0.2888 0.2893
Plasmodium vivax double C2-like domain-containing protein, putative 0.0033 0.0142 0.1553
Echinococcus multilocularis synaptotagmin 0.0033 0.0142 0.0142
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0053 0.0296
Schistosoma mansoni neuropeptide receptor 0.0429 0.2888 0.2888
Brugia malayi Variant SH3 domain containing protein 0.0165 0.1058 0.1239
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0034 0.015 0.015
Brugia malayi RhoGAP domain containing protein 0.0165 0.1058 0.1239
Brugia malayi Pleckstrin Homology Domain 0.0165 0.1058 0.1239
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.003 0.003
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0197 0.1283 0.1285
Leishmania major hypothetical protein, conserved 0.0036 0.0167 0.2376
Onchocerca volvulus 0.0146 0.0928 0.3199
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Schistosoma mansoni hypothetical protein 0.0016 0.003 0.003
Entamoeba histolytica C2 domain containing protein 0.0033 0.0142 0.0644
Brugia malayi Synapse defective protein 1 0.0033 0.0142 0.0147
Onchocerca volvulus Multiple C2 domain and transmembrane region protein homolog 0.0033 0.0142 0.0472
Echinococcus multilocularis synaptotagmin 0.0033 0.0142 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.002 0.0057 0.0567
Echinococcus granulosus fmrfamide receptor 0.0429 0.2888 0.2893
Schistosoma mansoni synaptotagmin 0.0033 0.0142 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0429 0.2888 0.2893
Brugia malayi putative neuropeptide receptor 0.0429 0.2888 0.3422
Plasmodium vivax hypothetical protein, conserved 0.0019 0.005 0.0136
Trypanosoma cruzi synaptotagmin, putative 0.0033 0.0142 0.2003
Brugia malayi WW domain containing protein 0.0033 0.0142 0.0147
Trypanosoma brucei Coiled-coil and C2 domain-containing protein 0.0033 0.0142 0.0863
Onchocerca volvulus 0.0429 0.2888 1
Brugia malayi Dopamine receptor protein 1 0.0429 0.2888 0.3422
Schistosoma mansoni diacylglycerol kinase theta 0.0165 0.1058 0.1058
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0336 0.3372
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0053 0.0279
Schistosoma mansoni ornithine--oxo-acid transaminase 0.002 0.0057 0.0057
Brugia malayi GnHR receptor homolog 0.0429 0.2888 0.3422
Schistosoma mansoni hypothetical protein 0.0016 0.003 0.003
Plasmodium vivax ferlin, putative 0.0033 0.0142 0.1553
Schistosoma mansoni ran 0.002 0.0054 0.0054
Schistosoma mansoni vav2 0.0165 0.1058 0.1058
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.024 0.1582 0.1938
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0685 0.4261
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus multilocularis survival motor neuron protein 1 0.027 0.1786 0.1789
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Toxoplasma gondii hypothetical protein 0.0053 0.0286 0.1643
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.002 0.0057 0.0567
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.1582 0.1582
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.002 0.0054 0.0061
Brugia malayi Adenylyl cyclase protein 0.0078 0.0455 0.0521
Echinococcus granulosus C2 calcium lipid binding region CaLB 0.0033 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Onchocerca volvulus 0.0033 0.0142 0.0472
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.0685 0.4436
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0914 0.0914
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0429 0.2888 0.2893
Echinococcus multilocularis serine:threonine protein kinase N2 0.0233 0.1531 0.1533
Schistosoma mansoni rac gtpase activating protein 0.0165 0.1058 0.1058
Echinococcus granulosus lamin dm0 0.0028 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0165 0.1058 0.1294
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0068 0.0392
Trypanosoma brucei C2 domain containing protein, putative 0.0033 0.0142 0.0863
Trichomonas vaginalis synaptotagmin 1,2, putative 0.0033 0.0142 0.0853
Schistosoma mansoni myosin xvIII 0.0429 0.2888 0.2888
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Onchocerca volvulus Ribonuclease H1 homolog 0.0027 0.0101 0.033
Toxoplasma gondii exonuclease III APE 0.0019 0.0046 0.0028
Onchocerca volvulus 0.0429 0.2888 1
Plasmodium falciparum importin beta, putative 0.0027 0.0104 0.4449
Echinococcus granulosus extended synaptotagmin 2 0.0033 0.0142 0.0142
Loa Loa (eye worm) synaptotagmin-1 0.0033 0.0142 0.0168
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.0685 0.1343
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0429 0.2888 0.2893
Schistosoma mansoni intermediate filament proteins 0.0028 0.0107 0.0107
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0107 0.0126
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.022 0.2777
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Leishmania major copine i-like protein 0.0033 0.0142 0.2003
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0429 0.2888 1
Onchocerca volvulus 0.0429 0.2888 1
Trypanosoma brucei ingi protein (ORF1) 0.0029 0.0116 0.0698
Schistosoma mansoni ap endonuclease 0.0019 0.0046 0.0046
Toxoplasma gondii Sma protein 0.0033 0.0142 0.067
Entamoeba histolytica DENN domain protein 0.0033 0.0142 0.0644
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0054 0.0714
Brugia malayi Variant SH3 domain containing protein 0.0033 0.0142 0.0147
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.1582 0.1584
Echinococcus multilocularis raf serine:threonine protein kinase 0.0165 0.1058 0.1059
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0078 0.0455 0.156
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0016 0.0028 0.0144
Echinococcus granulosus protein kinase c eta type 0.0165 0.1058 0.1059
Loa Loa (eye worm) hypothetical protein 0.0146 0.0928 0.1134
Entamoeba histolytica hypothetical protein 0.0022 0.0068 0.0149
Schistosoma mansoni synaptic ras gtpase activating protein syngap 0.0033 0.0142 0.0142
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0233 0.1531 0.1875
Echinococcus granulosus tm gpcr rhodopsin 0.0429 0.2888 0.2893
Mycobacterium tuberculosis Probable aminotransferase 0.0143 0.0905 0.1805
Loa Loa (eye worm) C2 domain-containing protein 0.0033 0.0142 0.0168
Leishmania major hypothetical protein, conserved 0.0014 0.0015 0.0146
Entamoeba histolytica hypothetical protein 0.0033 0.0142 0.0644
Onchocerca volvulus 0.0429 0.2888 1
Onchocerca volvulus 0.0033 0.0142 0.0472
Trypanosoma cruzi ISWI complex protein 0.0014 0.0015 0.0146
Schistosoma mansoni synaptotagmin 12 0.0033 0.0142 0.0142
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0028 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Schistosoma mansoni opsin-like receptor 0.0429 0.2888 0.2888
Echinococcus granulosus lamin 0.0028 0.0107 0.0107
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0171 0.1457
Loa Loa (eye worm) G-protein coupled receptor 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0042 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Brugia malayi Bromodomain containing protein 0.0039 0.0189 0.0204
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Echinococcus multilocularis protein piccolo 0.0033 0.0142 0.0142
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0046 0.0595
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0046 0.0033
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0073 0.0073
Brugia malayi follicle stimulating hormone receptor 0.0669 0.4548 0.5402
Loa Loa (eye worm) hypothetical protein 0.0045 0.0228 0.0274
Trypanosoma cruzi ribonuclease H1, putative 0.0027 0.0101 0.1401
Trichomonas vaginalis copine, putative 0.0033 0.0142 0.0853
Brugia malayi hypothetical protein 0.0429 0.2888 0.3422
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Trichomonas vaginalis ribonuclease H1, putative 0.0027 0.0101 0.0597
Entamoeba histolytica protein kinase, putative 0.0038 0.0176 0.0878
Toxoplasma gondii hypothetical protein 0.0033 0.0142 0.067
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Brugia malayi Hr1 repeat family protein 0.0233 0.1531 0.1803
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0233 0.1531 0.1875
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.002 0.0057 0.0046
Toxoplasma gondii AGC kinase 0.0233 0.1531 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Schistosoma mansoni biogenic amine receptor 0.0429 0.2888 0.2888
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0061 0.0338 0.2087
Echinococcus multilocularis adenylate cyclase type IX 0.0109 0.0674 0.0675
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0685 0.4261
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0027 0.0102 0.0102
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Schistosoma mansoni amine GPCR 0.0429 0.2888 0.2888
Trypanosoma brucei predicted C2 domain protein 0.0033 0.0142 0.0863
Onchocerca volvulus 0.0429 0.2888 1
Schistosoma mansoni hypothetical protein 0.0035 0.0162 0.0162
Echinococcus granulosus dna polymerase kappa 0.002 0.0053 0.0053
Onchocerca volvulus 0.0429 0.2888 1
Echinococcus granulosus intermediate filament protein 0.0028 0.0107 0.0107
Brugia malayi neuropeptide F receptor 0.0429 0.2888 0.3422
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.004 0.0513
Loa Loa (eye worm) hypothetical protein 0.0078 0.0455 0.0553
Plasmodium vivax ornithine aminotransferase, putative 0.002 0.0057 0.0231
Echinococcus granulosus neural cell expressed developmentally 0.0033 0.0142 0.0142
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.0685 0.0686
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0233 0.1531 0.9568
Mycobacterium tuberculosis Conserved protein 0.0111 0.0685 0.1343
Brugia malayi isocitrate dehydrogenase 0.0018 0.0042 0.0028
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0042 0.0207
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.2888 0.2888
Brugia malayi Synaptotagmin protein 3 0.0033 0.0142 0.0147
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Trypanosoma cruzi cAMP binding protein, putative 0.0036 0.0167 0.2376
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0001
Loa Loa (eye worm) C2 domain-containing protein 0.0033 0.0142 0.0168
Brugia malayi Synapse defective protein 1 0.0033 0.0142 0.0147
Brugia malayi Copine VIII 0.0033 0.0142 0.0147
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Schistosoma mansoni neuropeptide receptor 0.0429 0.2888 0.2888
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0053 0.0279
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0289 0.192 0.2353
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0171 0.0171
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Schistosoma mansoni biogenic amine (5HT) receptor 0.0429 0.2888 0.2888
Loa Loa (eye worm) hypothetical protein 0.0165 0.1058 0.1294
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0233 0.1531 0.1533
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0142 0.2003
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0103 0.0613
Echinococcus granulosus zinc finger protein 0.0023 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0033 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Loa Loa (eye worm) hypothetical protein 0.0035 0.0155 0.0185
Echinococcus granulosus neuropeptide Y receptor 0.0429 0.2888 0.2893
Schistosoma mansoni ran 0.002 0.0054 0.0054
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Brugia malayi Melatonin receptor type 1A 0.0429 0.2888 0.3422
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0429 0.2888 0.2893
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Echinococcus multilocularis Rac GTPase activating protein 1 0.0165 0.1058 0.1059
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0336 0.1975
Echinococcus granulosus peptide allatostatin:somatostatin 0.0429 0.2888 0.2893
Plasmodium vivax importin-beta 2, putative 0.0027 0.0104 0.0962
Brugia malayi C2 domain containing protein 0.0033 0.0142 0.0147
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0132 0.0132
Schistosoma mansoni synaptotagmin 0.0033 0.0142 0.0142
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0053 0.0695
Echinococcus granulosus synaptotagmin 2 0.0033 0.0142 0.0142
Echinococcus granulosus Diacylglycerol kinase theta 0.0165 0.1058 0.1059
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0685 0.4261
Loa Loa (eye worm) hypothetical protein 0.0111 0.0685 0.0835
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0053 0.0695
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0033 0.0142 0.0142
Loa Loa (eye worm) C2 domain-containing protein 0.0033 0.0142 0.0168
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Trichomonas vaginalis synaptotagmin, putative 0.0033 0.0142 0.0853
Brugia malayi phospholipase C homolog 0.0033 0.0142 0.0147
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0171 0.0182
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0053 0.0079
Brugia malayi protein kinase C II. 0.043 0.2898 0.3434
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0146 0.0928 0.1134
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.002 0.0057 0.0124
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0429 0.2888 0.2893
Brugia malayi RhoGAP domain containing protein 0.0165 0.1058 0.1239
Brugia malayi LD23056p 0.0033 0.0142 0.0147
Leishmania major hypothetical protein, conserved 0.0033 0.0142 0.2003
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.002 0.0054 0.0083
Leishmania major GTP-binding protein, putative 0.002 0.0054 0.0714
Echinococcus granulosus synaptotagmin 0.0033 0.0142 0.0142
Leishmania major c2 domain protein, putative 0.0033 0.0142 0.2003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0669 0.4548 0.5582
Brugia malayi protein kinase C3,putative 0.017 0.1092 0.1281
Entamoeba histolytica diacylglycerol kinase, putative 0.0165 0.1058 0.6814
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0243 0.0243
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0103 0.1442
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Schistosoma mansoni hypothetical protein 0.0034 0.015 0.015
Loa Loa (eye worm) Nedd4-PD 0.0033 0.0142 0.0168
Echinococcus multilocularis fmrfamide receptor 0.0429 0.2888 0.2893
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0338 0.2087
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.022 0.1199
Echinococcus multilocularis ornithine aminotransferase 0.002 0.0057 0.0057
Echinococcus multilocularis C2 calcium lipid binding region, CaLB 0.0033 0.0142 0.0142
Onchocerca volvulus Putative cc2d1b protein 0.0033 0.0142 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.1058 0.1058
Loa Loa (eye worm) neuropeptide F receptor 0.0429 0.2888 0.3542
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.2888 0.2893
Schistosoma mansoni hypothetical protein 0.0033 0.0142 0.0142
Leishmania major hypothetical protein, conserved 0.0033 0.0142 0.2003
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0042 0.0204 0.1243
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.002 0.0054 0.0886
Schistosoma mansoni biogenic amine (5HT) receptor 0.0429 0.2888 0.2888
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0078 0.0455 0.156
Trypanosoma brucei predicted C2 domain protein 0.0033 0.0142 0.0863
Loa Loa (eye worm) hypothetical protein 0.0429 0.2888 0.3542
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Entamoeba histolytica C2 domain containing protein 0.0033 0.0142 0.0644
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0053 0.0695
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0168
Loa Loa (eye worm) hypothetical protein 0.0311 0.2069 0.2537
Leishmania major protein kinase, putative 0.0018 0.004 0.0513
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0042 0.0204 0.1243
Onchocerca volvulus 0.0078 0.0455 0.156
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0053 0.0023
Echinococcus multilocularis serine:threonine protein kinase 38 0.0233 0.1531 0.1533
Brugia malayi hypothetical protein 0.0017 0.0037 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.1582 0.1582
Trichomonas vaginalis ran, putative 0.002 0.0054 0.0304
Brugia malayi intermediate filament protein 0.0028 0.0107 0.0106
Echinococcus multilocularis zinc finger protein 0.0023 0.0078 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0142 0.0853
Leishmania major c2 domain protein, putative 0.0033 0.0142 0.2003
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0338 0.2087
Onchocerca volvulus 0.0429 0.2888 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 10 uM Effective concentration required to achieve 50% protection of MT-4 cells against the cytopathic effect of HIV-1. ChEMBL. 7877143

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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