Detailed information for compound 319181

Basic information

Technical information
  • TDR Targets ID: 319181
  • Name: 6-tert-butyl-2-[(2R)-4-(3-chloropyridin-2-yl) -2-methylpiperazin-1-yl]-1H-benzimidazole
  • MW: 383.918 | Formula: C21H26ClN5
  • H donors: 1 H acceptors: 2 LogP: 5.53 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H]1CN(CCN1c1nc2c([nH]1)cc(cc2)C(C)(C)C)c1ncccc1Cl
  • InChi: 1S/C21H26ClN5/c1-14-13-26(19-16(22)6-5-9-23-19)10-11-27(14)20-24-17-8-7-15(21(2,3)4)12-18(17)25-20/h5-9,12,14H,10-11,13H2,1-4H3,(H,24,25)/t14-/m1/s1
  • InChiKey: ABWOTHSYSVRTCD-CQSZACIVSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-tert-butyl-2-[(2R)-4-(3-chloro-2-pyridyl)-2-methyl-piperazin-1-yl]-1H-benzimidazole
  • 6-tert-butyl-2-[(2R)-4-(3-chloro-2-pyridyl)-2-methyl-1-piperazinyl]-1H-benzimidazole
  • 6-tert-butyl-2-[(2R)-4-(3-chloropyridin-2-yl)-2-methyl-piperazin-1-yl]-1H-benzimidazole
  • 6-tert-butyl-2-[(2R)-4-(3-chloro-2-pyridyl)-2-methyl-piperazino]-1H-benzimidazole

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens transient receptor potential cation channel, subfamily V, member 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0029 0.0075
Loa Loa (eye worm) alpha-tubulin 0.1246 0.2371 0.7466
Leishmania major gamma-tubulin 0.0987 0.1872 0.5895
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.008 0.0126 0.0396
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0051 0.0537
Mycobacterium ulcerans hypothetical protein 0.0026 0.0023 0.0202
Onchocerca volvulus 0.0062 0.0092 0.0971
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0063 0.0188
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0023
Brugia malayi hypothetical protein 0.0027 0.0023 0.0073
Trichomonas vaginalis penicillin-binding protein, putative 0.0192 0.0341 0.1062
Schistosoma mansoni tyrosine kinase 0.0158 0.0277 0.074
Trichomonas vaginalis tubulin, putative 0.0506 0.0947 0.2972
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0009 0.0025
Echinococcus multilocularis tubulin alpha chain 0.1246 0.2371 0.237
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0034 0.0037 0.0114
Leishmania major beta tubulin 0.1664 0.3175 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0114 0.0359
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0287 0.0524 0.1648
Trypanosoma brucei alpha tubulin, putative 0.0506 0.0947 0.2972
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0009 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0061
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0043 0.0042
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0009 0.0025
Echinococcus granulosus tubulin alpha chain 0.1246 0.2371 0.6333
Echinococcus granulosus tubulin alpha 0.0929 0.176 0.4702
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trichomonas vaginalis ap endonuclease, putative 0.002 0.001 0.0017
Schistosoma mansoni apoferritin-2 0.0027 0.0023 0.0063
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Schistosoma mansoni hypothetical protein 0.0341 0.0629 0.168
Leishmania major beta tubulin 0.1664 0.3175 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0162 0.0283 0.0282
Leishmania major trypanothione reductase 0.0053 0.0074 0.0232
Schistosoma mansoni tubulin subunit beta 0.1664 0.3175 0.8484
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0077 0.0205
Schistosoma mansoni adapter molecule crk 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0065 0.0097 0.0302
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0025
Brugia malayi Immunoglobulin I-set domain containing protein 0.0027 0.0023 0.0073
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0114 0.0352
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Echinococcus multilocularis FTZ F1 alpha 0.0152 0.0264 0.0264
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0043 0.0054 0.017
Schistosoma mansoni zinc finger protein 0.0072 0.011 0.0293
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0824 0.1557 0.4898
Echinococcus granulosus beta tubulin 0.1664 0.3175 0.8483
Loa Loa (eye worm) integrin alpha pat-2 0.0263 0.0479 0.1507
Brugia malayi tubulin alpha chain - mouse 0.1246 0.2371 0.7466
Brugia malayi G-protein coupled receptor 0.0019 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) Smad1 0.0035 0.004 0.0123
Schistosoma mansoni intermediate filament proteins 0.003 0.003 0.008
Brugia malayi neuropeptide F receptor 0.0019 0.0009 0.003
Plasmodium falciparum tubulin epsilon chain, putative 0.0986 0.187 0.5881
Echinococcus multilocularis tubulin alpha chain 0.1246 0.2371 0.237
Loa Loa (eye worm) hypothetical protein 0.0825 0.156 0.4911
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0043 0.0055 0.0151
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0095 0.03
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0113 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.0422 0.0785 0.2463
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0152 0.0264 0.083
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0152 0.0264 0.0832
Loa Loa (eye worm) hypothetical protein 0.074 0.1396 0.4395
Schistosoma mansoni apoferritin-2 0.0027 0.0023 0.0063
Schistosoma mansoni ferritin 0.0027 0.0023 0.0063
Mycobacterium tuberculosis Probable oxidoreductase 0.0134 0.023 0.0958
Schistosoma mansoni steroid hormone receptor ad4bp 0.0152 0.0264 0.0706
Onchocerca volvulus 0.0019 0.0008 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0354 0.0653 0.2046
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0007 0.0016
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.005 0.0069 0.0203
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0009 0.0025
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0134 0.023 0.0958
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trichomonas vaginalis D-aminoacylase, putative 0.0192 0.0341 0.1062
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0114 0.0346
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0025
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0117 0.1373
Trypanosoma brucei epsilon tubulin 0.0986 0.187 0.5885
Loa Loa (eye worm) hypothetical protein 0.008 0.0126 0.0396
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0192 0.0341 0.0912
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0028 0.0074
Schistosoma mansoni transcription factor LCR-F1 0.008 0.0126 0.0337
Plasmodium falciparum tubulin gamma chain 0.0987 0.1872 0.5886
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0152 0.0264 0.0706
Echinococcus multilocularis mothers against decapentaplegic 6 0.0016 0.0002 0.0002
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0167 0.0293 0.0923
Loa Loa (eye worm) DR-78 0.0072 0.011 0.0344
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0192 0.0341 0.1075
Echinococcus granulosus tubulin alpha 1C chain 0.1246 0.2371 0.6333
Treponema pallidum cell division protein FtsZ 0.0422 0.0785 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Echinococcus granulosus g protein coupled receptor 0.0019 0.0009 0.0023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0024 0.0064
Schistosoma mansoni tubulin subunit alpha 0.0422 0.0785 0.2098
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.001 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0049 0.014
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0032 0.0034 0.0088
Plasmodium falciparum lipid/sterol:H+ symporter 0.005 0.0068 0.0193
Plasmodium vivax thioredoxin reductase, putative 0.0053 0.0074 0.0225
Schistosoma mansoni DNA helicase recq1 0.0032 0.0034 0.009
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0027 0.0024 0.0061
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0029 0.0028
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0055 0.0077 0.0076
Echinococcus multilocularis tubulin alpha 3 chain 0.1246 0.2371 0.237
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0008 0.0007
Schistosoma mansoni integrin alpha 0.0171 0.0301 0.0804
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Echinococcus multilocularis c src tyrosine kinase 0.0022 0.0014 0.0013
Toxoplasma gondii exonuclease III APE 0.002 0.001 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0152 0.0264 0.083
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0114 0.0357
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trichomonas vaginalis tubulin epsilon chain, putative 0.1246 0.2371 0.7463
Loa Loa (eye worm) hypothetical protein 0.0053 0.0074 0.0232
Brugia malayi Variant SH3 domain containing protein 0.0015 0.0001 0.0002
Mycobacterium tuberculosis Probable lipase LipE 0.0192 0.0341 0.1437
Plasmodium vivax vivapain-2 0.0019 0.0008 0.0018
Trichomonas vaginalis tubulin, putative 0.1664 0.3175 1
Brugia malayi Probable isocitrate dehydrogenase 0.002 0.0011 0.0035
Echinococcus multilocularis lamin dm0 0.003 0.003 0.0029
Echinococcus granulosus follistatin 0.0043 0.0054 0.0142
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0152 0.0264 0.083
Trypanosoma brucei beta tubulin 0.0929 0.176 0.5537
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0009 0.0009
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0087 0.0272
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0009 0.0025
Echinococcus granulosus Niemann Pick C1 protein 0.1179 0.2241 0.5987
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0082 0.0081
Echinococcus multilocularis Tubulin beta 2C chain 0.1664 0.3175 0.3175
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0019 0.0008 0.0022
Echinococcus granulosus Tubulin beta 2C chain 0.1664 0.3175 0.8483
Leishmania major beta tubulin 0.1664 0.3175 1
Schistosoma mansoni tubulin subunit beta 0.1664 0.3175 0.8484
Leishmania major epsilon tubulin, putative 0.0986 0.187 0.589
Schistosoma mansoni Smad4 0.0016 0.0002 0.0006
Brugia malayi MH2 domain containing protein 0.0035 0.004 0.0125
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0009 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0113 0.0342
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0009 0.0009
Brugia malayi sodium-independent organic anion transporter family protein 0.0062 0.0092 0.0289
Echinococcus granulosus L aminoadipate semialdehyde 0.0268 0.0489 0.1304
Brugia malayi Cathepsin L-like precursor 0.0019 0.0008 0.0025
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0007 0.0009
Giardia lamblia Epsilon tubulin 0.048 0.0895 0.2804
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0247 0.0661
Brugia malayi conserved hypotetical protein 0.0072 0.011 0.0346
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.0092
Mycobacterium ulcerans putative regulatory protein 0.004 0.0049 0.0542
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0022 0.0014 0.0036
Echinococcus granulosus GPCR family 2 0.0065 0.0097 0.0256
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0152 0.0264 0.0264
Trichomonas vaginalis tubulin epsilon chain, putative 0.1664 0.3175 1
Leishmania major eukaryotic initiation factor 4a, putative 0.0027 0.0025 0.0077
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Entamoeba histolytica hypothetical protein 0.008 0.0126 0.0391
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0007 0.0023
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.008 0.0126 0.0336
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0008 0.0084
Echinococcus granulosus tyrosine protein kinase Src42A 0.0055 0.0077 0.0204
Mycobacterium tuberculosis Probable esterase LipL 0.0192 0.0341 0.1437
Schistosoma mansoni hypothetical protein 0.0308 0.0565 0.151
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0192 0.0341 0.1437
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0009
Onchocerca volvulus 0.0019 0.0008 0.0084
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0076 0.0117 0.1415
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0009
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0009 0.0023
Brugia malayi MH2 domain containing protein 0.0517 0.0968 0.3047
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0043 0.0054 0.017
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0009 0.0023
Trypanosoma brucei zeta tubulin, putative 0.1022 0.1939 0.6102
Brugia malayi ecdysteroid receptor 0.0152 0.0264 0.0832
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0114 0.0359
Brugia malayi Muscleblind-like protein 0.015 0.026 0.0818
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0061
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.016
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0052 0.0138
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0117 0.0197 0.0197
Echinococcus granulosus Tubulin alpha 1 chain 0.1246 0.2371 0.6333
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0009 0.0009
Schistosoma mansoni tubulin subunit alpha 0.1246 0.2371 0.6334
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0022 0.0056
Echinococcus multilocularis beta LACTamase domain containing family member 0.0192 0.0341 0.0341
Brugia malayi Protein kinase domain containing protein 0.0158 0.0277 0.0872
Brugia malayi neuropeptide F receptor 0.0019 0.0009 0.003
Brugia malayi Steroid receptor seven-up type 2 0.0152 0.0264 0.0832
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0008 0.0021
Onchocerca volvulus 0.005 0.0068 0.0721
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0024 0.0062
Echinococcus granulosus fibroblast growth factor receptor 4 0.0117 0.0197 0.0526
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0052 0.0162
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0051
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0052 0.0138
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0009 0.003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0072 0.011 0.0109
Brugia malayi hypothetical protein 0.0019 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Schistosoma mansoni DNA helicase recq5 0.0032 0.0034 0.009
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0007 0.0023
Leishmania major beta tubulin 0.1664 0.3175 1
Loa Loa (eye worm) tubulin beta-2A chain 0.1664 0.3175 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0152 0.0264 0.0706
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0524 0.1639
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Giardia lamblia Alpha-tubulin 0.1246 0.2371 0.7461
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0008 0.0002
Loa Loa (eye worm) hypothetical protein 0.0062 0.0092 0.0287
Entamoeba histolytica hypothetical protein 0.008 0.0126 0.0391
Brugia malayi hypothetical protein 0.0053 0.0074 0.0234
Mycobacterium ulcerans esterase/lipase LipP 0.0192 0.0341 0.4293
Echinococcus multilocularis Smad4 0.0035 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0152 0.0264 0.083
Echinococcus granulosus agrin 0.0043 0.0054 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Brugia malayi Tubulin beta-1 chain 0.1664 0.3175 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0097 0.0096
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0052 0.0156
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0054 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Loa Loa (eye worm) hypothetical protein 0.008 0.0126 0.0396
Echinococcus multilocularis muscleblind protein 1 0.015 0.026 0.0259
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.001 0.0032
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0007 0.0009
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.001 0.0028
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0119 0.0202 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0024 0.0062
Leishmania major beta tubulin 0.1664 0.3175 1
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0129 0.0221 0.0695
Brugia malayi Patched related family protein 12 0.005 0.0068 0.0215
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0076 0.0117 0.1415
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0003 0.0009
Brugia malayi nuclear hormone receptor family member odr-7 0.0072 0.011 0.0346
Echinococcus multilocularis hypothetical protein 0.1246 0.2371 0.237
Trichomonas vaginalis tubulin alpha chain, putative 0.0506 0.0947 0.2972
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0126 0.0398
Trypanosoma cruzi epsilon tubulin, putative 0.0986 0.187 0.589
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.0092
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Leishmania major beta tubulin 0.1664 0.3175 1
Echinococcus multilocularis integrin alpha 3 0.0131 0.0224 0.0223
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0068 0.0181
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0052 0.0136
Loa Loa (eye worm) alpha-tubulin 0.1246 0.2371 0.7466
Toxoplasma gondii patched family protein 0.005 0.0068 0.0205
Brugia malayi MH1 domain containing protein 0.0019 0.0009 0.003
Brugia malayi Myosin head containing protein 0.005 0.0068 0.0215
Onchocerca volvulus 0.0019 0.0009 0.0099
Brugia malayi Tubulin beta chain 0.0506 0.0947 0.2982
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0114 0.0304
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0009 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0023
Echinococcus granulosus tyrosine protein kinase Src64B 0.0055 0.0077 0.0204
Brugia malayi hypothetical protein 0.008 0.0126 0.0398
Onchocerca volvulus 0.0072 0.011 0.116
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.005 0.0069 0.0216
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Echinococcus multilocularis tyrosine protein kinase HCK 0.004 0.0048 0.0047
Onchocerca volvulus 0.0054 0.0076 0.08
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0023
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Onchocerca volvulus 0.0019 0.0009 0.0099
Brugia malayi hypothetical protein 0.0062 0.0092 0.0289
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Schistosoma mansoni tyrosine kinase 0.0264 0.0479 0.128
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.004 0.0123
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0055 0.0077 0.0076
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0109 0.0344
Loa Loa (eye worm) glutaminase 0.0279 0.051 0.1604
Echinococcus multilocularis thioredoxin glutathione reductase 0.0053 0.0074 0.0073
Trichomonas vaginalis tubulin epsilon chain, putative 0.0422 0.0785 0.2463
Entamoeba histolytica hypothetical protein 0.008 0.0126 0.0391
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0082 0.0218
Echinococcus granulosus tumor protein p63 0.0378 0.0699 0.1865
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0354 0.0653 0.2056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0152 0.0264 0.083
Echinococcus granulosus thioredoxin glutathione reductase 0.0053 0.0074 0.0195
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.001 0.0031
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0002 0.0005
Brugia malayi Kelch motif family protein 0.0053 0.0074 0.0234
Brugia malayi mbt repeat family protein 0.005 0.0068 0.0215
Plasmodium falciparum alpha tubulin 2 0.1246 0.2371 0.7461
Brugia malayi hypothetical protein 0.0019 0.0009 0.003
Leishmania major beta tubulin 0.1664 0.3175 1
Onchocerca volvulus 0.0062 0.0092 0.0971
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0054 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0152 0.0264 0.0832
Echinococcus multilocularis cpg binding protein 0.0126 0.0214 0.0213
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0097 0.0304
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0023 0.0072
Schistosoma mansoni hypothetical protein 0.0341 0.0629 0.168
Schistosoma mansoni chromobox protein 0.0073 0.0113 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0069 0.0203
Echinococcus multilocularis epidermal growth factor receptor 0.0487 0.0909 0.0908
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0134 0.023 0.0723
Schistosoma mansoni smad1 5 8 and 0.0035 0.004 0.0106
Trichomonas vaginalis tubulin alpha chain, putative 0.0506 0.0947 0.2972
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0052 0.0149
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.0023 0.007
Brugia malayi beta-lactamase family protein 0.0192 0.0341 0.1075
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0043 0.0112
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.008 0.0126 0.0126
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0052 0.0149
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0032 0.0034 0.0083
Echinococcus granulosus Tubulin alpha 1 chain 0.1246 0.2371 0.6333
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0247 0.0659
Echinococcus granulosus tubulin alpha chain 0.1246 0.2371 0.6333
Brugia malayi G-protein coupled receptor 0.0019 0.0009 0.003
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0008 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0023
Brugia malayi Patched related family protein 10 0.005 0.0068 0.0215
Schistosoma mansoni ferritin 0.0027 0.0023 0.0063
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.0049 0.013
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.005 0.0069 0.0216
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trichomonas vaginalis tubulin beta chain, putative 0.1664 0.3175 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0052 0.014
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0074 0.0232
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0003 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0247 0.0247
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0047 0.0134
Brugia malayi Serotonin receptor 0.0019 0.0009 0.003
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0027 0.0025 0.026
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0268 0.0489 0.1537
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0009 0.0009
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0076 0.0238
Schistosoma mansoni nuclear hormone receptor 0.0152 0.0264 0.0706
Onchocerca volvulus Putative organic anion transporter 0.0062 0.0092 0.0971
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Trichomonas vaginalis glutaminase, putative 0.0279 0.051 0.1594
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0152 0.0264 0.0832
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0055 0.0077 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Echinococcus granulosus chromobox protein 1 0.0073 0.0113 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0062 0.0092 0.0287
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0167 0.0293 0.123
Brugia malayi Integrin beta pat-3 precursor 0.035 0.0646 0.2033
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0009 0.0025
Giardia lamblia Beta tubulin 0.1664 0.3175 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0055 0.0077 0.0204
Entamoeba histolytica cysteine protease, putative 0.0019 0.0008 0.0018
Trichomonas vaginalis tubulin beta chain, putative 0.0506 0.0947 0.2972
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0167 0.0293 0.0923
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.003 0.008
Plasmodium vivax RNA helicase-1, putative 0.0027 0.0025 0.0071
Loa Loa (eye worm) hypothetical protein 0.0062 0.0092 0.0287
Trichomonas vaginalis tubulin beta chain, putative 0.1246 0.2371 0.7463
Echinococcus multilocularis cysteine protease 0.0019 0.0008 0.0007
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0201 0.0359 0.0359
Onchocerca volvulus 0.0043 0.0054 0.0569
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0052 0.0136
Plasmodium vivax tubulin beta chain, putative 0.1664 0.3175 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0024 0.0062
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.007 0.0185
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0929 0.176 0.5539
Leishmania major beta tubulin 0.1664 0.3175 1
Schistosoma mansoni thyroid hormone receptor 0.0292 0.0535 0.1429
Brugia malayi Cell division protein ftsZ 0.0422 0.0785 0.2473
Mycobacterium ulcerans hypothetical protein 0.0192 0.0341 0.4293
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0095 0.0255
Loa Loa (eye worm) hypothetical protein 0.008 0.0126 0.0396
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0052 0.0162
Onchocerca volvulus 0.005 0.0068 0.0721
Plasmodium vivax tubulin alpha chain, putative 0.1246 0.2371 0.7465
Schistosoma mansoni integrin alpha-ps 0.0077 0.0119 0.0319
Echinococcus granulosus neuropeptide receptor A26 0.0534 0.0999 0.2668
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Echinococcus multilocularis integrin beta 2 0.0259 0.0471 0.047
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0027 0.0025 0.0077
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0152 0.0264 0.0706
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0025
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0042 0.0132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0167 0.0294 0.0786
Trichomonas vaginalis ap endonuclease, putative 0.002 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0009 0.0025
Echinococcus granulosus survival motor neuron protein 1 0.0264 0.0481 0.1282
Brugia malayi alpha-tubulin 0.1246 0.2371 0.7466
Echinococcus granulosus eukaryotic initiation factor 4A 0.0027 0.0025 0.0064
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0054 0.0159
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0109 0.0344
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.007 0.0219
Schistosoma mansoni agrin 0.0043 0.0054 0.0144
Loa Loa (eye worm) hypothetical protein 0.0043 0.0054 0.0167
Loa Loa (eye worm) hypothetical protein 0.0062 0.0092 0.0287
Onchocerca volvulus 0.0062 0.0092 0.0971
Schistosoma mansoni hypothetical protein 0.008 0.0126 0.0337
Schistosoma mansoni ferritin 0.0027 0.0023 0.0063
Echinococcus granulosus tubulin delta chain 0.0422 0.0785 0.2096
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0049 0.014
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0825 0.156 0.4908
Onchocerca volvulus Protein ultraspiracle homolog 0.0152 0.0264 0.2791
Loa Loa (eye worm) hypothetical protein 0.0043 0.0054 0.0167
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0047 0.0134
Echinococcus granulosus Nuclear hormone receptor HR96 0.0072 0.011 0.0291
Mycobacterium tuberculosis Probable hydrolase 0.0192 0.0341 0.1437
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0422 0.0785 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0929 0.176 0.5537
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.001 0.0011
Schistosoma mansoni hypothetical protein 0.1959 0.3743 1
Brugia malayi Dopamine receptor 0.0019 0.0009 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0334 0.104
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0057 0.0165
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.0366 0.1151
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.005 0.0069 0.0209
Schistosoma mansoni organic anion transporter 0.0062 0.0092 0.0246
Schistosoma mansoni ferritin light chain 0.0027 0.0023 0.0063
Schistosoma mansoni ferritin light chain 0.0027 0.0023 0.0063
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0009 0.003
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0264 0.0479 0.1279
Brugia malayi hypothetical protein 0.0019 0.0009 0.003
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0117 0.0356
Echinococcus granulosus g protein coupled receptor 0.0019 0.0009 0.0023
Echinococcus multilocularis nuclear receptor nhr 48 0.0072 0.011 0.0109
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0049 0.0049
Echinococcus granulosus lamin dm0 0.003 0.003 0.0078
Echinococcus granulosus orexin receptor type 2 0.0019 0.0009 0.0023
Schistosoma mansoni retinoic acid receptor RXR 0.0262 0.0476 0.1272
Echinococcus granulosus ferritin 0.0027 0.0023 0.0061
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0008 0.0019
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0023 0.0072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Echinococcus multilocularis tubulin alpha chain 0.1246 0.2371 0.237
Echinococcus multilocularis follistatin 0.0043 0.0054 0.0053
Leishmania major beta tubulin 0.1664 0.3175 1
Brugia malayi putative neuropeptide receptor 0.0019 0.0009 0.003
Echinococcus granulosus sterol regulatory element binding protein 0.0354 0.0653 0.1744
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0009 0.0009
Schistosoma mansoni Smad4 0.0035 0.004 0.0106
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0824 0.1557 0.4904
Brugia malayi RE15519p 0.0019 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Loa Loa (eye worm) RecQ helicase 0.0046 0.006 0.0188
Onchocerca volvulus 0.0268 0.0489 0.5162
Brugia malayi Tubulin alpha-2 chain 0.1246 0.2371 0.7466
Brugia malayi eukaryotic initiation factor 4A 0.0027 0.0025 0.0077
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.007 0.0207
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0009 0.003
Brugia malayi hypothetical protein 0.0266 0.0484 0.1525
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0009 0.0025
Loa Loa (eye worm) patched family protein 0.005 0.0068 0.0213
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0334 0.104
Schistosoma mansoni smad1 5 8 and 0.0035 0.004 0.0106
Schistosoma mansoni Smad4 0.0016 0.0002 0.0006
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.008 0.0126 0.0126
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0009 0.0009
Toxoplasma gondii beta tubulin 0.1664 0.3175 1
Entamoeba histolytica recQ family helicase, putative 0.0035 0.0039 0.0116
Brugia malayi beta-lactamase family protein 0.0192 0.0341 0.1075
Echinococcus multilocularis peroxisome assembly protein 26 0.1246 0.2371 0.237
Brugia malayi hypothetical protein 0.0257 0.0466 0.1468
Loa Loa (eye worm) intermediate filament protein 0.003 0.003 0.0092
Loa Loa (eye worm) hypothetical protein 0.0192 0.0341 0.1073
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0062 0.0092 0.0244
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Schistosoma mansoni adenoreceptor 0.0019 0.0009 0.0025
Schistosoma mansoni hypothetical protein 0.1296 0.2466 0.6589
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0023
Trypanosoma brucei beta tubulin 0.1664 0.3175 1
Onchocerca volvulus 0.0019 0.0009 0.0099
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0009 0.0009
Schistosoma mansoni nuclear receptor 0.0072 0.011 0.0293
Trypanosoma brucei beta tubulin 0.1664 0.3175 1
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0008 0.0025
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0009 0.0023
Mycobacterium ulcerans lipase LipD 0.0192 0.0341 0.4293
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.007 0.0221
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0054 0.0159
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.0049 0.0049
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0009 0.0009
Brugia malayi hypothetical protein 0.0072 0.011 0.0346
Entamoeba histolytica tartrate dehydrogenase, putative 0.002 0.0011 0.0028
Onchocerca volvulus Protein patched homolog 0.005 0.0068 0.0721
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0334 0.104
Schistosoma mansoni hypothetical protein 0.0341 0.0629 0.168
Brugia malayi Tubulin gamma chain 0.0987 0.1872 0.5895
Loa Loa (eye worm) hypothetical protein 0.0055 0.0078 0.0244
Plasmodium falciparum tubulin beta chain 0.1664 0.3175 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Schistosoma mansoni tyrosine kinase 0.0055 0.0077 0.0206
Echinococcus multilocularis tyrosine protein kinase Blk 0.0047 0.0063 0.0062
Schistosoma mansoni hypothetical protein 0.1959 0.3743 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0008 0.0011
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0002 0.0005
Treponema pallidum NADH oxidase 0.0018 0.0007 0.0049
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0009 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0037 0.0102
Trypanosoma cruzi zeta tubulin, putative 0.1022 0.1939 0.6107
Schistosoma mansoni nck2/grb4 0.0015 0.0001 0.0002
Echinococcus multilocularis Tubulin beta 2C chain 0.1664 0.3175 0.3175
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0062 0.0092 0.0091
Brugia malayi hypothetical protein 0.0019 0.0009 0.003
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0095 0.1133
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0023 0.0202
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Brugia malayi hypothetical protein 0.0019 0.0009 0.003
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0009 0.003
Onchocerca volvulus 0.0055 0.0078 0.0827
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.007
Echinococcus multilocularis expressed protein 0.0043 0.0054 0.0053
Echinococcus multilocularis protein dispatched 1 0.0404 0.075 0.0749
Brugia malayi Fibronectin type III domain containing protein 0.0027 0.0023 0.0073
Onchocerca volvulus Protein patched homolog 0.005 0.0068 0.0721
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0023 0.0017 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0044 0.0124
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.001 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Brugia malayi Thioredoxin reductase 0.0053 0.0074 0.0232
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0117 0.0197 0.0197
Schistosoma mansoni tubulin subunit beta 0.1664 0.3175 0.8484
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0008 0.0011
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0009 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0047 0.0134
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.002 0.0011 0.0016
Loa Loa (eye worm) MH2 domain-containing protein 0.0517 0.0968 0.3046
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0029
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0009 0.0027
Mycobacterium tuberculosis Cell division protein FtsZ 0.0422 0.0785 0.3348
Echinococcus granulosus mothers against decapentaplegic 2 0.0016 0.0002 0.0004
Loa Loa (eye worm) CHromoDomain protein family member 0.0019 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) CXXC zinc finger family protein 0.0119 0.0201 0.063
Brugia malayi Heterochromatin protein 1 0.0073 0.0113 0.0355
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0055 0.0077 0.0076
Trypanosoma brucei tubulin gamma chain 0.0987 0.1872 0.589
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0167 0.0293 0.0917
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0047 0.0134
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0245 0.0444 0.0443
Onchocerca volvulus 0.005 0.0068 0.0721
Onchocerca volvulus 0.0019 0.0008 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0022
Mycobacterium ulcerans cell division protein FtsZ 0.0422 0.0785 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0167 0.0293 0.0902
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.003 0.008
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0152 0.0264 0.083
Echinococcus multilocularis bloom syndrome protein 0.0046 0.006 0.006
Trichomonas vaginalis D-aminoacylase, putative 0.0192 0.0341 0.1062
Brugia malayi Nuclear hormone receptor E75 0.0072 0.011 0.0346
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0072 0.011 0.0109
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Plasmodium falciparum glutathione reductase 0.0053 0.0074 0.021
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.007 0.0221
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0057 0.0165
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0009 0.0009
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0032 0.0034 0.0088
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0095 0.0095
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0022 0.0192
Loa Loa (eye worm) tubulin beta chain 0.0422 0.0785 0.2471
Echinococcus multilocularis survival motor neuron protein 1 0.0264 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trichomonas vaginalis tubulin gamma chain, putative 0.0986 0.187 0.5885
Echinococcus granulosus intermediate filament protein 0.003 0.003 0.0078
Brugia malayi ORL1-like opioid receptor 0.0019 0.0009 0.003
Loa Loa (eye worm) tubulin alpha-3 chain 0.074 0.1396 0.4395
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.001 0.003
Echinococcus multilocularis sterol regulatory element binding protein 0.0354 0.0653 0.0653
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.007 0.0207
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0095 0.0155 0.0486
Echinococcus multilocularis tubulin alpha 3 chain 0.1246 0.2371 0.237
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0241 0.076
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0023 0.0017 0.0016
Schistosoma mansoni alpha tubulin 0.1246 0.2371 0.6334
Schistosoma mansoni myosin xvIII 0.0019 0.0009 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0025
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0057 0.06
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Brugia malayi mothers against decapentaplegic homolog 3 0.0016 0.0002 0.0007
Loa Loa (eye worm) steroid hormone receptor 0.0152 0.0264 0.083
Echinococcus granulosus Tubulin alpha 1 chain 0.1246 0.2371 0.6333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0009 0.0025
Brugia malayi AKH receptor 0.0019 0.0009 0.003
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Mycobacterium leprae Probable lipase LipE 0.0192 0.0341 0.4266
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0009 0.0009
Echinococcus granulosus Smad4 0.0035 0.004 0.0104
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0027 0.0025 0.0066
Onchocerca volvulus 0.005 0.0068 0.0721
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0167 0.0293 0.0911
Echinococcus granulosus roundabout 2 0.0033 0.0036 0.0094
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.001 0.0008
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.007 0.0207
Loa Loa (eye worm) hypothetical protein 0.0062 0.0092 0.0287
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0072 0.011 0.0291
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0167 0.0293 0.0911
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.008 0.0251
Toxoplasma gondii protease inhibitor PI2 0.0043 0.0054 0.0159
Schistosoma mansoni biogenic amine receptor 0.0019 0.0009 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Echinococcus granulosus insulin receptor 0.0158 0.0277 0.0738
Schistosoma mansoni cpg binding protein 0.0126 0.0214 0.0572
Loa Loa (eye worm) hypothetical protein 0.0152 0.0264 0.083
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0076 0.0117 0.0474
Leishmania major cathepsin L-like protease 0.0019 0.0008 0.0025
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0039 0.0123
Brugia malayi secreted modular calcium-binding protein 1 0.0043 0.0054 0.017
Brugia malayi Tubulin alpha chain 0.0422 0.0785 0.2473
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0141 0.0243 0.0647
Echinococcus granulosus tyrosine protein kinase Fyn 0.0055 0.0077 0.0204
Schistosoma mansoni nuclear receptor nhr-48 0.0072 0.011 0.0293
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.0023 0.0257
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Echinococcus multilocularis beta tubulin 0.1664 0.3175 0.3175
Loa Loa (eye worm) hypoxia-induced factor 1 0.0168 0.0296 0.0929
Brugia malayi Cathepsin L-like precursor 0.0019 0.0008 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0109 0.0344
Echinococcus granulosus mothers against decapentaplegic 6 0.0016 0.0002 0.0004
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0008 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0266 0.0484 0.1525
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0009 0.0027
Echinococcus granulosus Immunoglobulin 0.0023 0.0017 0.0043
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Trypanosoma cruzi tubulin gamma chain 0.0987 0.1872 0.5895
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Brugia malayi sodium-independent organic anion transporter family protein 0.0062 0.0092 0.0289
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0025
Brugia malayi nuclear receptor RXR 0.0072 0.011 0.0346
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Leishmania major beta tubulin 0.1664 0.3175 1
Mycobacterium tuberculosis Conserved protein 0.0192 0.0341 0.1437
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0247 0.0247
Echinococcus multilocularis Niemann Pick C1 protein 0.1179 0.2241 0.224
Echinococcus granulosus alpha tubulin 0.1246 0.2371 0.6333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0062 0.0092 0.0091
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0009 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.0354 0.1102
Trichomonas vaginalis tubulin beta chain, putative 0.1246 0.2371 0.7463
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0247 0.0661
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0152 0.0264 0.0832
Echinococcus multilocularis tubulin subunit beta 0.1664 0.3175 0.3175
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0025
Plasmodium falciparum ataxin-2 like protein, putative 0.0266 0.0484 0.1506
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.002 0.0011 0.001
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0152 0.0264 0.0706
Loa Loa (eye worm) ctsf protein 0.0019 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0023 0.0072
Onchocerca volvulus 0.0506 0.0947 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0055 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.0192 0.0341 0.1073
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0012 0.0024
Onchocerca volvulus 0.0019 0.0009 0.0099
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0009 0.0099
Brugia malayi hypothetical protein 0.0019 0.0009 0.003
Leishmania major beta tubulin 0.1664 0.3175 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0029 0.0028
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0022 0.007
Toxoplasma gondii patched family protein 0.005 0.0068 0.0205
Schistosoma mansoni hypothetical protein 0.0119 0.0202 0.0539
Loa Loa (eye worm) tubulin alpha chain 0.1246 0.2371 0.7466
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.001 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0044 0.0124
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.0366 0.1153
Schistosoma mansoni alpha tubulin 0.1246 0.2371 0.6334
Brugia malayi MH1 domain containing protein 0.0035 0.004 0.0125
Schistosoma mansoni opsin-like receptor 0.0019 0.0009 0.0025
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.001 0.0009
Echinococcus multilocularis roundabout 2 0.0033 0.0036 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0152 0.0264 0.0264
Schistosoma mansoni isocitrate dehydrogenase 0.002 0.0011 0.0029
Echinococcus granulosus epidermal growth factor receptor 0.0264 0.0479 0.1279
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.0354 0.1102
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) TK protein kinase 0.0047 0.0063 0.0195
Schistosoma mansoni ferritin 0.0027 0.0023 0.0063
Leishmania major hypothetical protein, conserved 0.0192 0.0341 0.1075
Trichomonas vaginalis D-aminoacylase, putative 0.0192 0.0341 0.1062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0019 0.0046
Echinococcus granulosus single minded 2 0.004 0.0049 0.013
Echinococcus granulosus beta LACTamase domain containing family member 0.0192 0.0341 0.091
Loa Loa (eye worm) hypothetical protein 0.0192 0.0341 0.1073
Trypanosoma cruzi alpha tubulin, putative 0.1246 0.2371 0.7466
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Loa Loa (eye worm) tubulin alpha 2 0.0317 0.0583 0.1833
Echinococcus granulosus expressed protein 0.0027 0.0023 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0044 0.0124
Echinococcus granulosus tyrosine protein kinase ABL1 0.0245 0.0444 0.1184
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0009 0.003
Echinococcus multilocularis expressed conserved protein 0.0775 0.1463 0.1463
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0047 0.0134
Schistosoma mansoni hypothetical protein 0.0065 0.0097 0.0258
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0029 0.0078
Schistosoma mansoni neuropeptide receptor 0.0019 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0032
Onchocerca volvulus 0.0192 0.0341 0.3604
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0053 0.0074 0.0232
Echinococcus granulosus muscleblind protein 0.015 0.026 0.0692
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0009 0.0027
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1664 0.3175 0.3175
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Brugia malayi Bloom's syndrome protein homolog 0.0046 0.006 0.0191
Onchocerca volvulus 0.0456 0.085 0.8976
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0161 0.0282 0.0281
Schistosoma mansoni hypothetical protein 0.0341 0.0629 0.168
Loa Loa (eye worm) hypothetical protein 0.0182 0.0323 0.1015
Loa Loa (eye worm) BEN-1 protein 0.1664 0.3175 1
Loa Loa (eye worm) tubulin alpha chain 0.1246 0.2371 0.7466
Echinococcus granulosus allatostatin A receptor 0.0019 0.0009 0.0023
Schistosoma mansoni tubulin subunit alpha 0.1246 0.2371 0.6334
Loa Loa (eye worm) hypothetical protein 0.0257 0.0466 0.1466
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.015 0.026 0.0816
Brugia malayi MH2 domain containing protein 0.0016 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0266 0.0484 0.1523
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Echinococcus granulosus neuropeptide s receptor 0.0534 0.0999 0.2668
Loa Loa (eye worm) TK/EGFR protein kinase 0.0487 0.0909 0.2861
Entamoeba histolytica tubulin family protein 0.1664 0.3175 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0004 0.0014
Schistosoma mansoni hypothetical protein 0.0065 0.0097 0.0258
Plasmodium falciparum ataxin-2 like protein, putative 0.0266 0.0484 0.1506
Schistosoma mansoni hypothetical protein 0.014 0.0241 0.0645
Echinococcus multilocularis tubulin alpha 1C chain 0.1246 0.2371 0.237
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.007 0.0211
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0152 0.0264 0.0704
Brugia malayi larval opioid receptor 0.0019 0.0009 0.003
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0109 0.0344
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0022 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Echinococcus granulosus integrin alpha ps 0.0077 0.0119 0.0317
Echinococcus granulosus peroxisome assembly protein 26 0.1246 0.2371 0.6333
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0034 0.0095
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Trypanosoma brucei epsilon tubulin 0.0929 0.176 0.5537
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Brugia malayi mbt repeat family protein 0.005 0.0068 0.0215
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0052 0.0162
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0027 0.0025 0.0064
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0023 0.0202
Brugia malayi beta-tubulin, identical 0.1664 0.3175 1
Leishmania major isocitrate dehydrogenase, putative 0.002 0.0011 0.0034
Toxoplasma gondii hypothetical protein 0.005 0.0068 0.0205
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Echinococcus multilocularis dnaJ subfamily B 0.1296 0.2466 0.2466
Toxoplasma gondii beta-tubulin, putative 0.1664 0.3175 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0009 0.0025
Echinococcus multilocularis epidermal growth factor receptor 0.0264 0.0479 0.0479
Onchocerca volvulus 0.0019 0.0009 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0061
Onchocerca volvulus 0.005 0.0068 0.0721
Leishmania major beta tubulin 0.1664 0.3175 1
Schistosoma mansoni lamin 0.003 0.003 0.008
Onchocerca volvulus 0.0019 0.0009 0.0099
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trypanosoma cruzi hypothetical protein, conserved 0.0192 0.0341 0.1075
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0009 0.0025
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0114 0.0359
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.011 0.0291
Schistosoma mansoni smad 0.0016 0.0002 0.0006
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0009 0.0009
Brugia malayi MAP kinase sur-1 0.0051 0.007 0.0221
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0078 0.0209
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.0093
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0027 0.0025 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0422 0.0785 0.2463
Echinococcus multilocularis integrin alpha ps 0.0077 0.0119 0.0119
Trypanosoma brucei trypanothione reductase 0.0053 0.0074 0.0219
Trypanosoma cruzi epsilon tubulin, putative 0.0986 0.187 0.589
Brugia malayi MH2 domain containing protein 0.0035 0.004 0.0125
Echinococcus multilocularis geminin 0.1959 0.3743 0.3742
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0334 0.104
Echinococcus multilocularis isocitrate dehydrogenase 0.0167 0.0293 0.0292
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0009 0.0025
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.004 0.0123
Brugia malayi nuclear receptor NHR-88 0.0152 0.0264 0.0832
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0009 0.0023
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0049 0.014
Echinococcus granulosus neuropeptide receptor 0.0019 0.0009 0.0023
Echinococcus multilocularis neuropeptide receptor A26 0.0534 0.0999 0.0998
Echinococcus multilocularis tubulin alpha 0.0929 0.176 0.176
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0022 0.0014 0.0038
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.005 0.0069 0.0216
Loa Loa (eye worm) hypothetical protein 0.0041 0.0051 0.0158
Echinococcus multilocularis tubulin gamma 1 chain 0.0987 0.1872 0.1871
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0023
Mycobacterium tuberculosis Probable reductase 0.0121 0.0204 0.0847
Echinococcus multilocularis protein patched 0.0354 0.0653 0.0653
Schistosoma mansoni cell adhesion molecule 0.003 0.003 0.0079
Echinococcus granulosus integrin beta 2 0.0259 0.0471 0.1257
Brugia malayi nuclear receptor RXR 0.008 0.0126 0.0398
Schistosoma mansoni biogenic amine receptor 0.0019 0.0009 0.0025
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0009 0.0023
Leishmania major beta tubulin 0.1664 0.3175 1
Onchocerca volvulus Bile acid receptor homolog 0.0152 0.0264 0.2791
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.005 0.0069 0.0209
Loa Loa (eye worm) hypothetical protein 0.0152 0.0264 0.083
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0009 0.0009
Echinococcus granulosus Solute carrier organic anion transporter family 0.0062 0.0092 0.0244
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0095 0.0379
Schistosoma mansoni glutaminase 0.0279 0.051 0.1362
Onchocerca volvulus 0.0192 0.0341 0.3604
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0008 0.0003
Leishmania major delta tubulin, putative 0.0781 0.1476 0.4647
Echinococcus multilocularis Niemann Pick C1 protein 0.0825 0.156 0.1559
Brugia malayi hypothetical protein 0.0019 0.0009 0.003
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.007 0.0207
Schistosoma mansoni opsin-like receptor 0.0019 0.0009 0.0025
Schistosoma mansoni nuclear receptor 0.0072 0.011 0.0293
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.007 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.007 0.0187
Plasmodium vivax tubulin alpha chain, putative 0.1246 0.2371 0.7465
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0027 0.0025 0.0064
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0068 0.0721
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0018 0.0042
Onchocerca volvulus 0.005 0.0068 0.0721
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0008 0.0007
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0167 0.0293 0.0292
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0076 0.0117 0.1415
Brugia malayi Melatonin receptor type 1A 0.0019 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Loa Loa (eye worm) hypothetical protein 0.008 0.0126 0.0396
Echinococcus multilocularis tyrosine protein kinase Srms 0.0047 0.0063 0.0062
Echinococcus granulosus tyrosine protein kinase HCK 0.004 0.0048 0.0127
Echinococcus granulosus tyrosine protein kinase Fyn 0.0055 0.0077 0.0204
Loa Loa (eye worm) hypothetical protein 0.0152 0.0264 0.083
Brugia malayi CHD4 protein 0.0019 0.0008 0.0025
Giardia lamblia Beta tubulin 0.1664 0.3175 1
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0201 0.0359 0.0958
Echinococcus granulosus hypothetical protein 0.0019 0.0009 0.0023
Loa Loa (eye worm) thioredoxin reductase 0.0053 0.0074 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0069 0.0203
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Giardia lamblia Sgs1 DNA helicase, putative 0.0032 0.0034 0.0083
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0422 0.0785 0.2463
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0097 0.0096
Echinococcus granulosus neuropeptide receptor 0.0019 0.0009 0.0023
Schistosoma mansoni tyrosine kinase 0.0117 0.0197 0.0528
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.001 0.003
Echinococcus multilocularis neuroglian 0.0027 0.0023 0.0023
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.007 0.0221
Plasmodium falciparum tubulin delta chain, putative 0.0422 0.0785 0.2456
Loa Loa (eye worm) hypothetical protein 0.0152 0.0264 0.083
Echinococcus multilocularis tubulin delta chain 0.0422 0.0785 0.0785
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0068 0.0183
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) TK/ABL protein kinase 0.0245 0.0444 0.1395
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0063 0.0185
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0152 0.0264 0.0832
Brugia malayi Tubulin alpha chain 0.1246 0.2371 0.7466
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0058
Brugia malayi Furin-like cysteine rich region family protein 0.0487 0.0909 0.2863
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.007 0.0199
Schistosoma mansoni integrin beta subunit 0.0206 0.0369 0.0985
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.002 0.0011 0.0027
Echinococcus granulosus cpg binding protein 0.0126 0.0214 0.057
Treponema pallidum ATP-dependent RNA helicase 0.0027 0.0025 0.0271
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0024 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.007 0.0069
Schistosoma mansoni tyrosine kinase 0.0257 0.0466 0.1245
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.005 0.0069 0.0181
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0838 0.1584 0.4233
Onchocerca volvulus 0.0019 0.0009 0.0099
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0082 0.0216
Echinococcus multilocularis tubulin alpha chain 0.1246 0.2371 0.237
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.001 0.003
Mycobacterium leprae cell division protein FtsZ 0.0422 0.0785 1
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0076 0.0117 0.0348
Mycobacterium ulcerans beta-lactamase 0.0192 0.0341 0.4293
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0025
Leishmania major cytochrome p450-like protein 0.0026 0.0022 0.007
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0049 0.0154
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0008 0.0011
Toxoplasma gondii histone lysine methyltransferase SET1 0.0229 0.0413 0.1292
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.007
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0119 0.0202 0.0537
Plasmodium falciparum alpha tubulin 1 0.1246 0.2371 0.7461
Brugia malayi CHE-14 protein 0.0354 0.0653 0.2057
Schistosoma mansoni nuclear hormone receptor 0.0072 0.011 0.0293
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0009 0.0027
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.005 0.0069 0.0216
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0025
Brugia malayi glutaminase DH11.1 0.0279 0.051 0.1606
Leishmania major beta tubulin 0.1664 0.3175 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0053 0.0074 0.0286
Onchocerca volvulus 0.0019 0.0009 0.0099
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Onchocerca volvulus 0.0032 0.0034 0.0357
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0268 0.0489 0.1539
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0097 0.0304
Schistosoma mansoni tyrosine kinase 0.0257 0.0466 0.1245
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0068 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0009
Echinococcus multilocularis L aminoadipate semialdehyde 0.0268 0.0489 0.0488
Trypanosoma brucei beta tubulin 0.1664 0.3175 1
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0524 0.1639
Schistosoma mansoni tyrosine kinase 0.0264 0.0479 0.128
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0068 0.0068
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0007 0.0016
Schistosoma mansoni follistatin 0.0043 0.0054 0.0144
Loa Loa (eye worm) fibroinase 0.0019 0.0008 0.0023
Echinococcus granulosus cathepsin l1 0.0019 0.0008 0.0019
Plasmodium vivax ataxin-2 like protein, putative 0.0266 0.0484 0.152
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0023 0.0072
Entamoeba histolytica tubulin alpha chain, putative 0.1246 0.2371 0.7465
Echinococcus granulosus histone acetyltransferase KAT2B 0.0156 0.0273 0.0728
Entamoeba histolytica protein kinase, putative 0.004 0.0048 0.0145
Trichomonas vaginalis tubulin alpha chain, putative 0.1664 0.3175 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0121 0.0204 0.0847
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0044 0.0124
Echinococcus granulosus smad 0.0035 0.004 0.0104
Schistosoma mansoni patched 1 0.0354 0.0653 0.1745
Schistosoma mansoni thyroid hormone receptor 0.0292 0.0535 0.1429
Trypanosoma brucei epsilon tubulin 0.0986 0.187 0.5885
Plasmodium falciparum eukaryotic initiation factor 4A 0.0027 0.0025 0.0055
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0114 0.0113
Echinococcus multilocularis smad 0.0035 0.004 0.0039
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0152 0.0264 0.0704
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0023 0.0072
Leishmania major beta tubulin 0.1664 0.3175 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0092 0.0287
Brugia malayi Serotonin receptor 0.0019 0.0009 0.003
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.007 0.0221
Echinococcus multilocularis sex peptide receptor 0.0019 0.0009 0.0009
Entamoeba histolytica tubulin alpha-1 chain 0.1246 0.2371 0.7465
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0047 0.0134
Loa Loa (eye worm) hypothetical protein 0.0129 0.0221 0.0693
Echinococcus multilocularis ferritin 0.0027 0.0023 0.0023
Brugia malayi protein-tyrosine kinase 0.0047 0.0063 0.0197
Trypanosoma cruzi tubulin delta chain 0.0781 0.1476 0.4647
Toxoplasma gondii transporter, major facilitator family protein 0.0062 0.0092 0.0279
Trypanosoma brucei alpha tubulin 0.1246 0.2371 0.7463
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0034 0.0106
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.002 0.0011 0.0035
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.002 0.0011 0.0035
Brugia malayi steroid hormone receptor 0.0152 0.0264 0.0832
Schistosoma mansoni hypothetical protein 0.0037 0.0043 0.0114
Schistosoma mansoni tubulin subunit delta 0.0422 0.0785 0.2098
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0192 0.0341 0.1437
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0072 0.011 0.0344
Echinococcus granulosus dnaJ subfamily B 0.1296 0.2466 0.6588
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0152 0.0264 0.0832
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0052 0.0136
Leishmania major cathepsin L-like protease 0.0019 0.0008 0.0025
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0055 0.0077 0.0076
Brugia malayi nuclear receptor NHR-67 0.0072 0.011 0.0346
Echinococcus multilocularis somatostatin receptor 0.0019 0.0009 0.0009
Onchocerca volvulus 0.003 0.003 0.0317
Loa Loa (eye worm) patched family protein 0.005 0.0068 0.0213
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Brugia malayi sodium-independent organic anion transporter family protein 0.0062 0.0092 0.0289
Echinococcus granulosus geminin 0.1959 0.3743 1
Leishmania major eukaryotic initiation factor 4a, putative 0.0027 0.0025 0.0077
Loa Loa (eye worm) tubulin gamma chain 0.0987 0.1872 0.5894
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.002 0.0011 0.0048
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0039 0.0123
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0009 0.0023
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0032 0.0034 0.0103
Onchocerca volvulus 0.0019 0.0008 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0023
Onchocerca volvulus 0.0019 0.0009 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0035 0.0096
Brugia malayi hypothetical protein 0.005 0.0068 0.0215
Echinococcus granulosus ecdysone induced protein 78C 0.0152 0.0264 0.0704
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0007 0.0023
Loa Loa (eye worm) nuclear receptor NHR-67 0.0072 0.011 0.0344
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0007 0.0009
Echinococcus granulosus Niemann Pick C1 protein 0.0825 0.156 0.4166
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0027 0.0025 0.0071
Echinococcus multilocularis cysteine protease 0.0019 0.0008 0.0007
Echinococcus granulosus tubulin epsilon chain 0.0986 0.187 0.4996
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0008 0.0011
Loa Loa (eye worm) tubulin beta-1 chain 0.1664 0.3175 1
Schistosoma mansoni coup transcription factor 0.0152 0.0264 0.0706
Brugia malayi glutathione reductase 0.0053 0.0074 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0029 0.0078
Brugia malayi Niemann-Pick C1 protein precursor 0.0825 0.156 0.4912
Echinococcus multilocularis insulin receptor 0.0158 0.0277 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0024 0.0062
Toxoplasma gondii cathepsin CPL 0.0019 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Echinococcus multilocularis serotonin receptor 0.0019 0.0009 0.0009
Plasmodium falciparum acyl-CoA synthetase 0.002 0.001 0.0009
Echinococcus multilocularis integrin alpha ps 0.0077 0.0119 0.0119
Leishmania major cathepsin L-like protease 0.0071 0.0109 0.0344
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0071
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0009 0.0009
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0016 0.0002 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0008 0.0003
Echinococcus multilocularis expressed protein 0.0027 0.0023 0.0023
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0027 0.0025 0.0055
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0114 0.0359
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0023 0.0068
Loa Loa (eye worm) BEN-1 protein 0.1664 0.3175 1
Brugia malayi Tubulin beta chain 0.0422 0.0785 0.2473
Brugia malayi MH1 domain containing protein 0.0035 0.004 0.0125
Onchocerca volvulus 0.0019 0.0009 0.0099
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0027 0.0025 0.0064
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.048 0.0895 0.2812
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Echinococcus granulosus Protein patched homolog 1 0.0354 0.0653 0.1744
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0068 0.0068
Echinococcus granulosus tm gpcr rhodopsin 0.0598 0.1123 0.2998
Trypanosoma brucei zeta tubulin 0.1022 0.1939 0.6102
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0023 0.0202
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0161 0.0282 0.0753
Mycobacterium tuberculosis Conserved protein 0.0192 0.0341 0.1437
Onchocerca volvulus 0.0019 0.0009 0.0099
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.002 0.0011 0.0048
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0027 0.0025 0.0024
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.001 0.0032
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0009 0.003
Brugia malayi SRC-1 0.0055 0.0077 0.0242
Onchocerca volvulus 0.005 0.0068 0.0721
Onchocerca volvulus 0.005 0.0068 0.0721
Brugia malayi MH1 domain containing protein 0.0019 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0076 0.0117 0.0359
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0072 0.011 0.0346
Brugia malayi prostaglandin transporter 0.0062 0.0092 0.0289
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.003 0.008
Brugia malayi nuclear receptor NHR-88 0.0072 0.011 0.0346
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0134 0.023 0.0958
Loa Loa (eye worm) agrin synaptic family protein 0.0043 0.0054 0.0167
Brugia malayi Cytochrome P450 family protein 0.0026 0.0022 0.007
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0029
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.0044 0.0128
Schistosoma mansoni tubulin subunit beta 0.0422 0.0785 0.2098
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0055 0.0152
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0049 0.014
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0009 0.0025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0008 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0023 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0023
Plasmodium vivax vivapain-2 0.0019 0.0008 0.0018
Toxoplasma gondii isocitrate dehydrogenase 0.0167 0.0293 0.0914
Echinococcus multilocularis Tubulin beta 2C chain 0.1664 0.3175 0.3175
Schistosoma mansoni histamine h1 receptor 0.0019 0.0009 0.0025
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0009 0.0023
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0095 0.0253
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Echinococcus multilocularis Tubulin alpha 1 chain 0.1246 0.2371 0.237
Echinococcus granulosus integrin alpha ps 0.0037 0.0043 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0008
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0003 0.001
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0009 0.0009
Schistosoma mansoni tubulin subunit epsilon 0.0986 0.187 0.4997
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0167 0.0293 0.0783
Toxoplasma gondii beta-1 tubulin, putative 0.1664 0.3175 1
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.002 0.0011 0.0035
Schistosoma mansoni tubulin subunit gamma 0.0987 0.1872 0.5001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0023 0.0202
Trichomonas vaginalis tubulin beta chain, putative 0.1246 0.2371 0.7463
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0072 0.011 0.0109
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0022 0.0067
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0009 0.0023
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0114 0.0303
Brugia malayi Dopamine receptor protein 1 0.0019 0.0009 0.003
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.001 0.026
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0063 0.0167
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0007 0.0023
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.003 0.0094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0009
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.004 0.0104
Schistosoma mansoni vesicular amine transporter 0.0027 0.0025 0.0066
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0004 0.0014
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0052 0.0051
Brugia malayi Probable isocitrate dehydrogenase 0.002 0.0011 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0152 0.0264 0.0832
Brugia malayi tailless protein 0.0072 0.011 0.0346
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0009 0.0023
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0032 0.0034 0.0033
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0025
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0121 0.0204 0.2493
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0029 0.0077
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0029 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0061
Leishmania major hypothetical protein, conserved 0.0266 0.0484 0.1525
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Echinococcus multilocularis Tubulin alpha 1 chain 0.1246 0.2371 0.237
Schistosoma mansoni chromobox protein 0.0073 0.0113 0.0301
Loa Loa (eye worm) TK/INSR protein kinase 0.0158 0.0277 0.087
Toxoplasma gondii ABC1 family protein 0.0192 0.0341 0.1065
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0034 0.0095
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0009 0.0009
Loa Loa (eye worm) tubulin alpha-2 chain 0.1246 0.2371 0.7466
Echinococcus multilocularis tumor protein p63 0.0378 0.0699 0.0698
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0252 0.0458 0.1222
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0072 0.011 0.116
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0049 0.014
Brugia malayi CXXC zinc finger family protein 0.0119 0.0201 0.0633
Leishmania major cathepsin L-like protease 0.0019 0.0008 0.0025
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0022 0.0067
Schistosoma mansoni tyrosine kinase 0.0237 0.0429 0.1146
Onchocerca volvulus 0.0019 0.0008 0.0084
Schistosoma mansoni cpg binding protein 0.0126 0.0214 0.0572
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0008 0.0084
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0019 0.0008 0.002
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Leishmania major cathepsin L-like protease 0.0071 0.0109 0.0344
Brugia malayi SPARC precursor 0.0043 0.0054 0.017
Trypanosoma cruzi beta tubulin, putative 0.1664 0.3175 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0008 0.0011
Brugia malayi intermediate filament protein 0.003 0.003 0.0094
Toxoplasma gondii tubulin, putative 0.0057 0.0082 0.0248
Onchocerca volvulus 0.0019 0.0008 0.0084
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0032 0.0034 0.0033
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.004 0.0106
Loa Loa (eye worm) TK protein kinase 0.004 0.0048 0.0149
Loa Loa (eye worm) hypothetical protein 0.0043 0.0054 0.0167
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0141 0.0243 0.0242
Schistosoma mansoni tyrosine kinase 0.0158 0.0277 0.074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0268 0.0489 0.1306
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0072 0.011 0.116
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0029
Onchocerca volvulus 0.0072 0.011 0.116
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Echinococcus granulosus tyrosine protein kinase Fyn 0.0055 0.0077 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0024 0.0062
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0134 0.023 0.2827
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) TK protein kinase 0.012 0.0204 0.064
Echinococcus multilocularis beta tubulin 0.1664 0.3175 0.3175
Schistosoma mansoni retinoid-x-receptor (RXR) 0.008 0.0126 0.0338
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0054 0.0143
Schistosoma mansoni tyrosine kinase 0.0487 0.0909 0.2429
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0027 0.0025 0.0075
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0009 0.0009
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0121 0.0204 0.0847
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0001 0.0002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0063 0.0185
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0023 0.0066
Onchocerca volvulus Putative organic anion transporter 0.0062 0.0092 0.0971
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0004 0.0012
Schistosoma mansoni single-minded 0.0054 0.0077 0.0205
Echinococcus multilocularis integrin alpha ps 0.0037 0.0043 0.0042
Onchocerca volvulus 0.0062 0.0092 0.0971
Brugia malayi ecdysone receptor 0.0072 0.011 0.0346
Echinococcus multilocularis Immunoglobulin 0.0023 0.0017 0.0016
Brugia malayi GnHR receptor homolog 0.0019 0.0009 0.003
Echinococcus multilocularis 0.0149 0.026 0.0259
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0071
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0043 0.0132
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0052 0.0162
Onchocerca volvulus 0.0019 0.0009 0.0099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0052 0.0149
Echinococcus granulosus integrin alpha 3 0.0131 0.0224 0.0597
Leishmania major cathepsin L-like protease 0.0071 0.0109 0.0344
Onchocerca volvulus Glucosylceramidase homolog 0.0188 0.0334 0.3529
Loa Loa (eye worm) SRC-1 0.0055 0.0077 0.024
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0004 0.0014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0009 0.0027
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0009 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0524 0.1639
Echinococcus granulosus Tubulin beta 2C chain 0.1664 0.3175 0.8483
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.001 0.0081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0008 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0008 0.0003
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1226 0.2331 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.1246 0.2371 0.7463
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0152 0.0264 0.0832
Loa Loa (eye worm) hypothetical protein 0.0192 0.0341 0.1073
Giardia lamblia Beta tubulin 0.1664 0.3175 1
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0009 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0044 0.0124
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trichomonas vaginalis tubulin, putative 0.0481 0.0897 0.2815
Brugia malayi G protein-coupled receptor 0.0019 0.0009 0.003
Echinococcus granulosus tubulin alpha chain 0.1246 0.2371 0.6333
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0055 0.0077 0.0076
Onchocerca volvulus 0.0026 0.0023 0.0243
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.003 0.0092
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0008 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0152 0.0264 0.0832
Echinococcus multilocularis mothers against decapentaplegic 2 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0051
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0192 0.0341 0.4293
Echinococcus granulosus c src tyrosine kinase 0.0022 0.0014 0.0036
Brugia malayi tubulin alpha-2 chain 0.1246 0.2371 0.7466
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0008 0.0007
Trichomonas vaginalis helicase, putative 0.0027 0.0024 0.0061
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0204 0.0642
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0009 0.0099
Brugia malayi Isocitrate dehydrogenase 0.0167 0.0293 0.0923
Echinococcus granulosus Tubulin beta 2C chain 0.1664 0.3175 0.8483
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.005 0.0069 0.0183
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Brugia malayi Variant SH3 domain containing protein 0.0015 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Schistosoma mansoni opsin-like receptor 0.0019 0.0009 0.0025
Loa Loa (eye worm) cysteine protease 0.0019 0.0008 0.0023
Giardia lamblia GTOR 0.005 0.0069 0.0194
Echinococcus multilocularis Tubulin alpha 1 chain 0.1246 0.2371 0.237
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Trichomonas vaginalis penicillin-binding protein, putative 0.0192 0.0341 0.1062
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Loa Loa (eye worm) hypothetical protein 0.0434 0.0807 0.2538
Echinococcus granulosus tubulin alpha 3 chain 0.1246 0.2371 0.6333
Echinococcus granulosus tubulin beta 4A class IVa 0.1664 0.3175 0.8483
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.001 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0008 0.0011
Schistosoma mansoni tyrosine kinase 0.0022 0.0014 0.0038
Echinococcus multilocularis tubulin beta 1 chain 0.1664 0.3175 0.3175
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0008 0.0025
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0009 0.0025
Loa Loa (eye worm) glutaminase 2 0.0279 0.051 0.1604
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.007 0.0069
Onchocerca volvulus 0.003 0.003 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0192 0.0341 0.1073
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0524 0.1639
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0192 0.0341 0.0912
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Echinococcus granulosus neuroglian 0.0027 0.0023 0.006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0152 0.0264 0.0704
Trypanosoma brucei alpha tubulin 0.1246 0.2371 0.7463
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0524 0.1639
Trichomonas vaginalis tubulin epsilon chain, putative 0.1664 0.3175 1
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Trichomonas vaginalis tubulin, putative 0.0506 0.0947 0.2972
Brugia malayi orphan nuclear receptor NR2E1 0.0072 0.011 0.0346
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0027 0.0025 0.0064
Brugia malayi hypothetical protein 0.0456 0.085 0.2677
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0008 0.0084
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0008 0.0002
Loa Loa (eye worm) hypothetical protein 0.008 0.0126 0.0396
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0262 0.0476 0.1271
Schistosoma mansoni neuropeptide receptor 0.0019 0.0009 0.0025
Schistosoma mansoni alpha tubulin 0.1246 0.2371 0.6334
Onchocerca volvulus 0.0192 0.0341 0.3604
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0063 0.0062
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0023 0.0202
Schistosoma mansoni nuclear hormone receptor 0.0072 0.011 0.0293
Loa Loa (eye worm) hypothetical protein 0.0062 0.0092 0.0287
Leishmania major beta tubulin 0.1664 0.3175 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0015 0.0001 0.0002
Echinococcus granulosus expressed conserved protein 0.0775 0.1463 0.3909
Leishmania major beta tubulin 0.1664 0.3175 1
Schistosoma mansoni amine GPCR 0.0019 0.0009 0.0025
Loa Loa (eye worm) beta-lactamase 0.0192 0.0341 0.1073
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Entamoeba histolytica tubulin gamma chain 0.0987 0.1872 0.5893
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0049 0.0154
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.0023 0.0209
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Onchocerca volvulus 0.0019 0.0009 0.0099
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0009 0.003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0152 0.0264 0.0264
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1246 0.2371 0.7463
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0009
Brugia malayi hypothetical protein 0.0072 0.011 0.0346
Loa Loa (eye worm) hypothetical protein 0.003 0.0029 0.0089
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0167 0.0293 0.0292
Echinococcus multilocularis muscleblind protein 0.015 0.026 0.0259
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.001 0.0024
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0017
Loa Loa (eye worm) phosphatidylinositol 3 0.005 0.0069 0.0214
Leishmania major phosphopantetheinyl transferase-like protein 0.0076 0.0117 0.0369
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.011 0.0109
Schistosoma mansoni ap endonuclease 0.002 0.001 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Brugia malayi hypothetical protein 0.008 0.0126 0.0398
Echinococcus granulosus tyrosine kinase 0.0047 0.0063 0.0166
Loa Loa (eye worm) integrin beta-2 0.035 0.0646 0.2032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0023
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0023 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Loa Loa (eye worm) hypothetical protein 0.0094 0.0153 0.0481
Echinococcus granulosus bloom syndrome protein 0.0046 0.006 0.016
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0152 0.0264 0.0704
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0143 0.0247 0.0777
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.002 0.0011 0.0021
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0097 0.0302
Trypanosoma brucei protein kinase, putative 0.0051 0.007 0.0207
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0076 0.0117 0.1457
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0009 0.0023
Schistosoma mansoni tyrosine kinase 0.0257 0.0466 0.1245
Echinococcus granulosus FTZ F1 alpha 0.0152 0.0264 0.0704
Brugia malayi hypothetical protein 0.0172 0.0303 0.0953
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0023 0.0068
Schistosoma mansoni survival motor neuron protein 0.0054 0.0076 0.0202
Schistosoma mansoni organic anion transporter 0.0062 0.0092 0.0246
Brugia malayi nuclear hormone receptor family member nhr-6 0.0072 0.011 0.0346
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0192 0.0341 0.1073
Brugia malayi photoreceptor-specific nuclear receptor 0.0152 0.0264 0.0832
Echinococcus granulosus fmrfamide receptor 0.0019 0.0009 0.0023
Giardia lamblia Gamma tubulin 0.0987 0.1872 0.5886
Schistosoma mansoni tyrosine kinase 0.0022 0.0014 0.0038
Onchocerca volvulus Putative organic anion transporter 0.0062 0.0092 0.0971
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.015 0.026 0.0816
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.001 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0025
Toxoplasma gondii alpha-tubulin I, putative 0.1246 0.2371 0.7464
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0004 0.0014
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.0456 0.085 0.2675
Onchocerca volvulus 0.0019 0.0009 0.0099
Loa Loa (eye worm) hypothetical protein 0.0152 0.0264 0.083
Echinococcus granulosus g protein coupled receptor 0.0019 0.0009 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0192 0.0341 0.1062
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0055 0.0168
Onchocerca volvulus 0.0119 0.0201 0.2122
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0152 0.0264 0.0264
Schistosoma mansoni tubulin subunit beta 0.1664 0.3175 0.8484
Trypanosoma brucei beta tubulin 0.1664 0.3175 1
Toxoplasma gondii alpha tubulin TUBA1 0.1246 0.2371 0.7464
Trichomonas vaginalis ferritin, putative 0.0027 0.0023 0.006
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0019 0.0008 0.0007
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0009 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0061
Echinococcus multilocularis chromobox protein 1 0.0073 0.0113 0.0112
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0334 0.104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0023 0.0155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0109 0.0331
Trypanosoma cruzi hypothetical protein, conserved 0.0192 0.0341 0.1075
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0028 0.0074
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0019 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0057 0.0082 0.0255
Echinococcus granulosus tubulin alpha chain 0.1246 0.2371 0.6333
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0287 0.0524 0.165
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0113 0.0353
Plasmodium vivax glutathione reductase, putative 0.0053 0.0074 0.0225
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0047 0.0063 0.0166
Toxoplasma gondii isocitrate dehydrogenase 0.0167 0.0293 0.0914
Echinococcus granulosus tubulin subunit beta 0.1664 0.3175 0.8483
Echinococcus multilocularis serotonin receptor 0.0019 0.0009 0.0009
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0152 0.0264 0.0706
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0044 0.0124
Schistosoma mansoni blooms syndrome DNA helicase 0.003 0.0029 0.0078
Schistosoma mansoni integrin alpha-ps 0.004 0.0049 0.013
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.008 0.0126 0.0335
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0152 0.0264 0.0264
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0068 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0097 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0052 0.0149
Loa Loa (eye worm) hypothetical protein 0.1246 0.2371 0.7466
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0009 0.0009
Loa Loa (eye worm) tubulin alpha 2 0.0824 0.1557 0.4904
Loa Loa (eye worm) hypothetical protein 0.0192 0.0341 0.1073
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0069 0.0203
Entamoeba histolytica tubulin family protein 0.1664 0.3175 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0032 0.0034 0.0104
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0023 0.0202
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0009 0.0009
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0007 0.0012
Schistosoma mansoni biogenic amine receptor 0.0019 0.0009 0.0025
Brugia malayi hypothetical protein 0.0182 0.0323 0.1017
Loa Loa (eye worm) hypothetical protein 0.0264 0.0481 0.1512
Schistosoma mansoni RAR-like nuclear receptor 0.0152 0.0264 0.0706
Brugia malayi Cytochrome P450 family protein 0.0026 0.0022 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0024 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0023
Brugia malayi hypothetical protein 0.0264 0.0481 0.1514
Echinococcus granulosus somatostatin receptor 0.0019 0.0009 0.0023
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0167 0.0293 0.0923
Trichomonas vaginalis tubulin beta chain, putative 0.1246 0.2371 0.7463
Echinococcus granulosus twitchin 0.0027 0.0024 0.0063
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0008 0.0007
Echinococcus multilocularis musashi 0.003 0.003 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0061
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0025
Trichomonas vaginalis esterase, putative 0.0192 0.0341 0.1062
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0009 0.0023
Brugia malayi Dopamine receptor protein 2 0.0019 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0029
Brugia malayi Patched protein homolog 1 0.005 0.0068 0.0215
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0152 0.0264 0.0706
Brugia malayi hypothetical protein 0.0062 0.0092 0.0289
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.004 0.0039
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0003 0.001
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0082 0.0216
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) patched family protein 0.005 0.0068 0.0213
Mycobacterium tuberculosis Conserved protein 0.0192 0.0341 0.1437
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0007 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0009 0.0025
Echinococcus granulosus isocitrate dehydrogenase NAD 0.002 0.0011 0.0027
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0151
Echinococcus granulosus tyrosine protein kinase Blk 0.0047 0.0063 0.0166
Brugia malayi isocitrate dehydrogenase 0.0167 0.0293 0.0923
Plasmodium vivax tubulin epsilon chain, putative 0.0986 0.187 0.5887
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0023 0.0066
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Brugia malayi Cathepsin L-like precursor 0.0019 0.0008 0.0025
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0167 0.0293 0.0781
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.004 0.0104
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0063 0.0188
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0008 0.0011
Plasmodium falciparum thioredoxin reductase 0.0053 0.0074 0.021
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.001 0.0024
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0152 0.0264 0.0704
Schistosoma mansoni neuropeptide receptor 0.0019 0.0009 0.0025
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0008 0.0018
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.002 0.0011 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0152 0.0264 0.083
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0121 0.0204 0.0847
Trichomonas vaginalis tubulin alpha chain, putative 0.0506 0.0947 0.2972
Onchocerca volvulus 0.0152 0.0264 0.2791
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0152 0.0264 0.0832
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0027 0.0025 0.0066
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0027 0.0023 0.0209
Brugia malayi nuclear hormone receptor 0.0152 0.0264 0.0832
Entamoeba histolytica hypothetical protein 0.0076 0.0117 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0054 0.0158
Brugia malayi Integrin alpha pat-2 precursor 0.0171 0.0301 0.0948
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0051 0.0147
Loa Loa (eye worm) hypothetical protein 0.0354 0.0653 0.2056
Schistosoma mansoni unc-13 (munc13) 0.002 0.0011 0.0029
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0143 0.0247 0.0779
Echinococcus granulosus Tubulin beta 2C chain 0.1664 0.3175 0.8483
Loa Loa (eye worm) tubulin alpha 2 0.0824 0.1557 0.4904
Echinococcus multilocularis thyroid hormone receptor alpha 0.0292 0.0535 0.0534
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0009 0.0023
Brugia malayi Cathepsin L-like precursor 0.0019 0.0008 0.0025
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0072 0.011 0.0293
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0082 0.0257
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0019
Echinococcus granulosus tubulin alpha chain 0.1246 0.2371 0.6333
Schistosoma mansoni neuropeptide receptor 0.0019 0.0009 0.0025
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0095 0.03
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0524 0.1639
Schistosoma mansoni tubulin subunit alpha 0.1246 0.2371 0.6334
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0095 0.1133
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0247 0.0661
Leishmania major beta tubulin 0.1664 0.3175 1
Echinococcus granulosus defective proboscis extension response 0.0023 0.0017 0.0043
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.007 0.0221
Brugia malayi protein C24B5.3 0.005 0.0068 0.0215
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0027 0.0025 0.0077
Echinococcus multilocularis lamin 0.003 0.003 0.0029
Onchocerca volvulus 0.0019 0.0009 0.0099
Trypanosoma cruzi zeta tubulin, putative 0.1022 0.1939 0.6107
Schistosoma mansoni tyrosine kinase 0.0055 0.0077 0.0206
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0162 0.0283 0.0755
Trichomonas vaginalis tubulin gamma chain, putative 0.1664 0.3175 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0167 0.0293 0.0292
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0008 0.0025
Echinococcus granulosus epidermal growth factor receptor 0.0487 0.0909 0.2427
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0043 0.0054 0.017
Loa Loa (eye worm) tubulin beta chain 0.1664 0.3175 1
Loa Loa (eye worm) MBCTL1 0.0057 0.0082 0.0255
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0182 0.0322 0.0321
Schistosoma mansoni hypothetical protein 0.0141 0.0243 0.0649
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0192 0.0341 0.1437
Brugia malayi Sex muscle abnormal protein 5 0.0015 0.0001 0.0002
Echinococcus granulosus lamin 0.003 0.003 0.0078
Echinococcus granulosus sex peptide receptor 0.0019 0.0009 0.0023
Toxoplasma gondii thioredoxin reductase 0.0053 0.0074 0.0222
Brugia malayi hypothetical protein 0.0019 0.0009 0.003
Loa Loa (eye worm) nuclear factor I 0.0019 0.0009 0.0027
Loa Loa (eye worm) beta-tubulin 0.1664 0.3175 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0152 0.0264 0.0832
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0055 0.0152
Trypanosoma cruzi MFS transporter, putative 0.0062 0.0092 0.0289
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0055 0.0077 0.0076
Schistosoma mansoni lamin 0.003 0.003 0.008
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0506 0.0947 0.2972
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0247 0.0659
Trypanosoma brucei tubulin delta chain 0.0781 0.1476 0.464
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0071
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0121 0.0204 0.0847
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0044 0.0124
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.007 0.0221
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0009 0.0025
Trichomonas vaginalis tubulin gamma chain, putative 0.0422 0.0785 0.2463
Echinococcus granulosus tubulin gamma 1 chain 0.0987 0.1872 0.5
Echinococcus multilocularis tubulin alpha 1C chain 0.1246 0.2371 0.237
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0009 0.0023
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.007 0.0185
Echinococcus multilocularis ecdysone induced protein 78C 0.0152 0.0264 0.0264
Toxoplasma gondii patched family protein 0.005 0.0068 0.0205
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0009 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0152 0.0264 0.083
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0097 0.0256
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0009 0.0027
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0055 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.007
Loa Loa (eye worm) acetyltransferase 0.0161 0.0282 0.0885
Mycobacterium leprae conserved hypothetical protein 0.0192 0.0341 0.4266
Trypanosoma brucei alpha tubulin 0.1246 0.2371 0.7463
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0008 0.0011
Brugia malayi Tubulin alpha-2 chain 0.1246 0.2371 0.7466
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0167 0.0293 0.0292
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0072 0.011 0.0293
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0009 0.0023
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0006
Onchocerca volvulus 0.004 0.0049 0.0522
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0121 0.0204 0.0847
Schistosoma mansoni tubulin subunit beta 0.1664 0.3175 0.8484
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0037 0.0116
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0027 0.0025 0.0071
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.0023 0.007
Trichomonas vaginalis DNA helicase recq, putative 0.0035 0.0039 0.011
Brugia malayi Cathepsin L-like precursor 0.0019 0.0008 0.0025
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.005 0.0069 0.0203
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.005 0.0069 0.0068
Plasmodium vivax tubulin gamma chain, putative 0.0987 0.1872 0.5893
Trypanosoma cruzi tubulin delta chain 0.0781 0.1476 0.4647
Leishmania major cathepsin L-like protease 0.0019 0.0008 0.0025
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0054 0.0159
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.001 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0051 0.0147
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0126 0.0398
Echinococcus multilocularis chromobox protein 1 0.0073 0.0113 0.0112
Onchocerca volvulus 0.0019 0.0008 0.0084
Echinococcus granulosus nuclear receptor nhr 48 0.0072 0.011 0.0291
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0075
Schistosoma mansoni smad1 5 8 and 0.0035 0.004 0.0106
Brugia malayi bHLH-PAS transcription factor 0.004 0.0049 0.0156
Trichomonas vaginalis tubulin beta chain, putative 0.1246 0.2371 0.7463
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0009 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0152 0.0264 0.0832
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0004 0.0011
Mycobacterium ulcerans glutaminase 0.0279 0.051 0.6461
Loa Loa (eye worm) patched family protein 0.005 0.0068 0.0213
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0027 0.0025 0.0064
Plasmodium vivax hypothetical protein, conserved 0.0192 0.0341 0.1069
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0152 0.0264 0.0704
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0009 0.0023
Trichomonas vaginalis tubulin gamma chain, putative 0.0987 0.1872 0.589
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0004 0.001
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0152 0.0264 0.2791
Entamoeba histolytica recQ family DNA helicase 0.0016 0.0003 0.0004
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0039 0.011
Onchocerca volvulus 0.0062 0.0092 0.0971
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0152 0.0264 0.083
Echinococcus multilocularis agrin 0.0043 0.0054 0.0053
Brugia malayi hypothetical protein 0.008 0.0126 0.0398
Echinococcus granulosus thyroid hormone receptor alpha 0.0072 0.011 0.0291
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0009 0.0027
Entamoeba histolytica hypothetical protein 0.008 0.0126 0.0391
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0022 0.0067
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.0023 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0061
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.0366 0.1153
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0034 0.0106
Echinococcus granulosus tubulin subunit TubB 0.1246 0.2371 0.6333
Echinococcus granulosus beta tubulin 0.1664 0.3175 0.8483
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0076 0.0117 0.0363
Brugia malayi Patched related family protein 4 0.005 0.0068 0.0215
Schistosoma mansoni nephrin 0.003 0.003 0.0079
Leishmania major zeta tubulin, putative 0.1022 0.1939 0.6107
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.002 0.0011 0.0032
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0068 0.0181
Giardia lamblia Alpha-tubulin 0.1246 0.2371 0.7461
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0008 0.0019
Trypanosoma brucei alpha tubulin 0.1246 0.2371 0.7463
Echinococcus multilocularis tubulin alpha chain 0.1246 0.2371 0.237
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0001 0.0002
Echinococcus multilocularis Tubulin beta 2C chain 0.1664 0.3175 0.3175
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0152 0.0264 0.0264
Schistosoma mansoni hypothetical protein 0.0065 0.0097 0.0258
Brugia malayi chromobox protein homolog 3 0.0041 0.0051 0.016
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0334 0.104
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0023 0.0202
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0009 0.0025
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.0023 0.0161
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Schistosoma mansoni cpg binding protein 0.0119 0.0201 0.0537
Brugia malayi Tyrosine-protein kinase abl-1 0.0142 0.0246 0.0775
Brugia malayi protein C24B5.3 0.005 0.0068 0.0215
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0009 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0152 0.0264 0.083
Schistosoma mansoni hypothetical protein 0.0054 0.0076 0.0202
Schistosoma mansoni tubulin subunit beta 0.1664 0.3175 0.8484
Loa Loa (eye worm) hypothetical protein 0.0043 0.0054 0.0167
Echinococcus multilocularis GPCR, family 2 0.0065 0.0097 0.0096
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0029
Brugia malayi Nuclear hormone receptor E75 0.0072 0.011 0.0346
Loa Loa (eye worm) transcription factor SMAD2 0.0517 0.0968 0.3046
Brugia malayi hypothetical protein 0.005 0.0068 0.0215
Echinococcus granulosus tubulin beta 1 chain 0.1664 0.3175 0.8483
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0213
Toxoplasma gondii patched family protein 0.005 0.0068 0.0205
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0082 0.0081
Onchocerca volvulus 0.0019 0.0009 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0049 0.014
Brugia malayi nuclear hormone receptor 0.0072 0.011 0.0346
Echinococcus multilocularis Immunoglobulin 0.0023 0.0017 0.0016
Schistosoma mansoni hypothetical protein 0.0065 0.0097 0.0258
Trichomonas vaginalis DNA helicase recq1, putative 0.0046 0.006 0.0177
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.008 0.0126 0.0338
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0047 0.0134
Trypanosoma brucei PAB1-binding protein , putative 0.0266 0.0484 0.1514
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0009 0.0009
Trichomonas vaginalis tubulin beta chain, putative 0.1246 0.2371 0.7463
Brugia malayi hypothetical protein 0.005 0.0068 0.0215
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0004 0.0014
Brugia malayi hypothetical protein 0.0019 0.0009 0.003
Brugia malayi Smad1 0.0035 0.004 0.0125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0047 0.0134
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.002 0.0011 0.001
Loa Loa (eye worm) isocitrate dehydrogenase 0.0167 0.0293 0.0921
Brugia malayi Nuclear hormone receptor-like 1 0.0152 0.0264 0.0832
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0027 0.0025 0.0024
Echinococcus multilocularis tubulin subunit TubB 0.1246 0.2371 0.237
Brugia malayi sulfakinin receptor protein 0.0257 0.0466 0.1468
Leishmania major alpha tubulin 0.1246 0.2371 0.7466
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0009 0.0009
Echinococcus granulosus chromobox protein 1 0.0073 0.0113 0.0299
Trichomonas vaginalis DNA helicase recq, putative 0.0046 0.006 0.0177
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0043 0.0054 0.017
Loa Loa (eye worm) hypothetical protein 0.0205 0.0366 0.1151
Schistosoma mansoni ap endonuclease 0.002 0.001 0.0026
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0097 0.0256
Echinococcus multilocularis tubulin epsilon chain 0.0986 0.187 0.187
Brugia malayi Tyrosine-protein kinase abl-1 0.011 0.0184 0.0579
Echinococcus multilocularis Tubulin beta 2C chain 0.1664 0.3175 0.3175
Echinococcus granulosus tubulin alpha 3 chain 0.1246 0.2371 0.6333
Onchocerca volvulus 0.0019 0.0009 0.0099
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0005 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.0334 0.104
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0003 0.0007
Brugia malayi Cathepsin L-like precursor 0.0019 0.0008 0.0025
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0023 0.0155
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0076 0.0117 0.0359
Loa Loa (eye worm) nuclear hormone receptor 0.0072 0.011 0.0344
Trypanosoma cruzi PAB1-binding protein , putative 0.0266 0.0484 0.1525
Brugia malayi acetyltransferase, GNAT family protein 0.0161 0.0282 0.0887
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0781 0.1476 0.4641
Schistosoma mansoni smad 0.0035 0.004 0.0106
Brugia malayi beta-lactamase 0.0192 0.0341 0.1075
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0055 0.0077 0.0204
Echinococcus multilocularis tyrosine protein kinase Abl 0.011 0.0184 0.0183
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0072
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0344
Brugia malayi Patched family protein 0.005 0.0068 0.0215
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0063 0.0192
Echinococcus granulosus Tubulin beta 2C chain 0.1664 0.3175 0.8483
Echinococcus granulosus serotonin receptor 0.0019 0.0009 0.0023
Echinococcus granulosus Nuclear hormone receptor HR96 0.0072 0.011 0.0291
Loa Loa (eye worm) hypothetical protein 0.014 0.0241 0.0758
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.074 0.1396 0.4388
Plasmodium vivax patched family protein, putative 0.005 0.0068 0.0208
Brugia malayi hypothetical protein 0.005 0.0068 0.0215
Brugia malayi hypoxia-induced factor 1 0.0168 0.0296 0.0932
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0009
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0076 0.0117 1
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0068 0.0183
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0023 0.0066
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0009 0.0009
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0007 0.0023
Loa Loa (eye worm) glutathione reductase 0.0053 0.0074 0.023
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0027
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0025
Echinococcus multilocularis neuropeptide s receptor 0.0534 0.0999 0.0998
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0598 0.1123 0.1122
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0022 0.0014 0.0013
Giardia lamblia Delta tubulin 0.0422 0.0785 0.2456
Loa Loa (eye worm) tubulin beta-4 chain 0.1664 0.3175 1
Loa Loa (eye worm) patched family protein 0.005 0.0068 0.0213
Loa Loa (eye worm) hypothetical protein 0.0032 0.0034 0.0103
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0008 0.0023
Echinococcus granulosus tyrosine protein kinase Lyn 0.0055 0.0078 0.0206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0008 0.0011
Mycobacterium tuberculosis Probable lipase LipD 0.0192 0.0341 0.1437
Echinococcus granulosus tubulin alpha 1C chain 0.1246 0.2371 0.6333
Plasmodium vivax delta tubulin, putative 0.0422 0.0785 0.2468
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.005 0.0069 0.0216
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0824 0.1557 0.4904
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0062 0.0092 0.0287
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0152 0.0264 0.0832
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0117 0.0197 0.0526
Toxoplasma gondii LsmAD domain-containing protein 0.0266 0.0484 0.1516
Brugia malayi PAS domain containing protein 0.0054 0.0077 0.0241
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0009 0.0009
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0008 0.0023
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0023 0.0017 0.0045

Activities

Activity type Activity value Assay description Source Reference
CL (ADMET) = 8 l hr-1 kg-1 Clearance value of the compound was determined in rat at single dose of 30 mg/kg oral dose ChEMBL. 15664844
CL (ADMET) = 8.02 l hr-1 kg-1 Clearance value of the compound was determined in rat at single dose of 3 mg/kg intravenously ChEMBL. 15664844
Cmax (ADMET) = 300 ng ml-1 Cmax value of the compound was determined in rat at single dose of 30 mg/kg oral dose ChEMBL. 15664844
F (ADMET) = 19.7 % Bioavailability of the compound was determined in rat at single dose of 3 mg/kg intravenously ChEMBL. 15664844
F (ADMET) = 19.7 % Bioavailability in rat (single dose 30 mg/kg p.o.) ChEMBL. 15664844
IC50 (functional) = 90 nM Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as blockade of capsaicin-induced receptor activation by FLIPR assay ChEMBL. 17489570
IC50 (functional) = 90 nM Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as blockade of capsaicin-induced receptor activation by FLIPR assay ChEMBL. 17489570
IC50 (functional) = 90.4 nM Antagonist activity in capsaicin-induced FLIPR assays in HEK293 cells expressing human TRPV1 ChEMBL. 15664844
IC50 (functional) = 90.4 nM Antagonist activity in capsaicin-induced FLIPR assays in HEK293 cells expressing human TRPV1 ChEMBL. 15664844
IC50 (functional) = 104 nM Antagonist activity in pH 5.5-induced FLIPR assays in HEK293 cells expressing human TRPV1 ChEMBL. 15664844
IC50 (functional) = 104 nM Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as blockade of acid-induced receptor activation by FLIPR assay ChEMBL. 17489570
IC50 (functional) = 104 nM Antagonist activity in pH 5.5-induced FLIPR assays in HEK293 cells expressing human TRPV1 ChEMBL. 15664844
IC50 (functional) = 104 nM Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as blockade of acid-induced receptor activation by FLIPR assay ChEMBL. 17489570
T max (ADMET) = 3 hr Time taken for cmax value of the compound was determined in rat at single dose of 30 mg/kg oral dose ChEMBL. 15664844
T1/2 (ADMET) = 0.56 hr Terminal half life value of the compound was determined in rat at single dose of 3 mg/kg intravenously ChEMBL. 15664844
T1/2 (ADMET) = 0.6 hr Terminal half life value of the compound was determined in rat at single dose of 30 mg/kg oral dose ChEMBL. 15664844
Vd (ADMET) = 6.87 l kg-1 Volume distribution of the compound was determined in rat at single dose of 3 mg/kg intravenously ChEMBL. 15664844

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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