Detailed information for compound 320672

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 585.18 | Formula: C29H33ClN4O3S2
  • H donors: 2 H acceptors: 3 LogP: 5.76 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(Nc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccc(s1)Cl)CN1CCN(CC1)c1ccccc1
  • InChi: 1S/C29H33ClN4O3S2/c30-26-10-11-28(38-26)39(36,37)32-29-21-6-7-22(29)17-23-18-24(9-8-20(23)16-21)31-27(35)19-33-12-14-34(15-13-33)25-4-2-1-3-5-25/h1-5,8-11,18,21-22,29,32H,6-7,12-17,19H2,(H,31,35)
  • InChiKey: PFTCBIBMHGBWSG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens APH1B gamma secretase subunit Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis gamma secretase subunit aph 1 Get druggable targets OG5_130831 All targets in OG5_130831
Loa Loa (eye worm) gamma-secretase subunit aph-1 Get druggable targets OG5_130831 All targets in OG5_130831
Schistosoma mansoni gamma-secretase subunit aph-1 Get druggable targets OG5_130831 All targets in OG5_130831
Echinococcus granulosus gamma secretase subunit aph 1 Get druggable targets OG5_130831 All targets in OG5_130831
Brugia malayi gamma-secretase subunit aph-1 Get druggable targets OG5_130831 All targets in OG5_130831
Schistosoma japonicum ko:K06172 anterior pharynx defective 1, putative Get druggable targets OG5_130831 All targets in OG5_130831
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0183 0.0183
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.002 0.0045 0.0093
Mycobacterium tuberculosis Conserved protein 0.0027 0.0075 0.0177
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0251 0.1086 0.1623
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0019 0.0037 0.0056
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0123 0.0511 0.0756
Loa Loa (eye worm) steroid hormone receptor 0.0133 0.0554 0.0828
Schistosoma mansoni hypothetical protein 0.0028 0.0078 0.0114
Leishmania major cathepsin L-like protease 0.0019 0.0037 0.0296
Echinococcus multilocularis epidermal growth factor receptor 0.0029 0.0085 0.0085
Trypanosoma cruzi DNA topoisomerase II, putative 0.0022 0.0055 0.0458
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Schistosoma mansoni netrin receptor unc5 0.0049 0.0174 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Brugia malayi putative neuropeptide receptor NPR1 0.0028 0.0078 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0065 0.0483
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0018 0.0037 0.0558
Loa Loa (eye worm) hypothetical protein 0.0055 0.0204 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0028 0.0195
Trypanosoma brucei cdc2-related kinase 3 0.0021 0.005 0.0416
Leishmania major protein kinase, putative 0.0018 0.0034 0.0267
Loa Loa (eye worm) hypothetical protein 0.0047 0.0164 0.0245
Onchocerca volvulus 0.0091 0.0363 0.0894
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0018 0.0033 0.0483
Echinococcus granulosus ribonuclease H1 0.0014 0.0017 0.0025
Brugia malayi Cytochrome P450 family protein 0.002 0.0045 0.0068
Echinococcus multilocularis protein tyrosine kinase 0.0232 0.0999 0.0999
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.1492 0.669 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0178 0.0265
Echinococcus multilocularis activin receptor type 0.0028 0.0079 0.0079
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.002 0.0046 0.0094
Echinococcus granulosus RUN 0.0205 0.0878 0.1312
Loa Loa (eye worm) hypothetical protein 0.0175 0.0744 0.1113
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0078 0.0078
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0131 0.1013
Schistosoma mansoni ran 0.0022 0.0053 0.0076
Echinococcus multilocularis lamin 0.002 0.0044 0.0044
Brugia malayi Protein kinase domain containing protein 0.0234 0.1011 0.1512
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0085 0.0338 0.084
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0039 0.0131 0.0324
Brugia malayi cell division control protein 2 homolog 0.0021 0.005 0.0075
Trichomonas vaginalis ran, putative 0.0022 0.0053 0.0391
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0183 0.0183
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0085 0.0338 0.084
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0012 0.0006 0.0007
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0028 0.0078 0.0078
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Plasmodium falciparum thioredoxin reductase 0.0051 0.0183 0.0266
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.0045 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0009 0.0039
Echinococcus multilocularis netrin receptor unc 5 0.0049 0.0174 0.0174
Plasmodium falciparum DNA gyrase subunit B 0.0059 0.0221 0.0323
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0106 0.0431 0.3973
Schistosoma mansoni thyroid hormone receptor 0.0133 0.0554 0.0825
Leishmania major glycerol uptake protein, putative 0.0251 0.1086 1
Brugia malayi RNase H family protein 0.0014 0.0017 0.0025
Plasmodium vivax importin-beta 2, putative 0.003 0.0089 0.0125
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0021 0.005 0.0067
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0078 0.0114
Echinococcus granulosus Nuclear hormone receptor HR96 0.0063 0.0237 0.0354
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0028 0.0195
Onchocerca volvulus 0.0027 0.0075 0.0185
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0037 0.0343
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0183 0.0266
Echinococcus multilocularis cysteine protease 0.0019 0.0037 0.0037
Toxoplasma gondii thioredoxin reductase 0.0051 0.0183 0.0266
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0018 0.0032 0.0476
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0078 0.0078
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0044 0.0151 0.0226
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0059 0.0221 0.1976
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0133 0.0554 0.0554
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0742 0.5855
Echinococcus multilocularis 6 phosphofructokinase 0.0065 0.0246 0.0246
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0036 0.0114 0.1054
Echinococcus granulosus sterol regulatory element binding protein 0.006 0.0225 0.0337
Loa Loa (eye worm) glutaminase 0.029 0.1264 0.189
Mycobacterium tuberculosis Conserved protein 0.0027 0.0075 0.0177
Echinococcus multilocularis sex peptide receptor 0.0028 0.0078 0.0078
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0037 0.0056
Echinococcus granulosus alpha 1A adrenergic receptor 0.0028 0.0078 0.0117
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0023 0.0056 0.0083
Echinococcus multilocularis protein patched 0.006 0.0225 0.0225
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0034 0.0105 0.0157
Schistosoma mansoni amine GPCR 0.0028 0.0078 0.0114
Mycobacterium tuberculosis Probable reductase 0.0116 0.0477 0.12
Echinococcus multilocularis GPCR, family 2 0.0055 0.0204 0.0204
Echinococcus granulosus lipoxygenase domain containing protein 0.0205 0.0878 0.1312
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0251 0.1086 0.1623
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0036 0.0114 0.017
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0027 0.0075 0.0177
Plasmodium vivax vivapain-2 0.0019 0.0037 0.0048
Brugia malayi RNase H family protein 0.0014 0.0017 0.0025
Schistosoma mansoni nuclear receptor nhr-48 0.0063 0.0237 0.0351
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0009 0.0011
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0044 0.0151 0.0151
Brugia malayi gamma-secretase subunit aph-1 0.0296 0.1289 0.1927
Echinococcus multilocularis nibrin 0.0012 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0034 0.0105 0.0105
Loa Loa (eye worm) cytochrome P450 0.002 0.0045 0.0068
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0033 0.0256
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0037 0.0053
Echinococcus multilocularis survival motor neuron protein 1 0.0484 0.2137 0.2137
Echinococcus granulosus cyclin dependent kinase 5 0.0021 0.005 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0045 0.0325
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.002 0.0045 0.0093
Trypanosoma cruzi DNA topoisomerase II, putative 0.0022 0.0055 0.0458
Loa Loa (eye worm) melatonin receptor type 1A 0.0028 0.0078 0.0117
Echinococcus multilocularis smoothened 0.0151 0.0637 0.0637
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0133 0.0554 0.0828
Loa Loa (eye worm) hypothetical protein 0.0074 0.0287 0.0428
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0251 0.1086 0.1623
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0076 0.0571
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0251 0.1086 0.162
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0085 0.0338 0.0847
Schistosoma mansoni hypothetical protein 0.0125 0.0518 0.0772
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0013 0.0014 0.0079
Echinococcus multilocularis tyrosine protein kinase Abl 0.002 0.0041 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0078 0.0114
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0036 0.0114 0.0114
Schistosoma mansoni opsin-like receptor 0.0028 0.0078 0.0114
Brugia malayi hypothetical protein 0.0161 0.0681 0.1018
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0251 0.1086 0.1086
Loa Loa (eye worm) doublecortin family protein 0.0205 0.0878 0.1312
Echinococcus granulosus protein kinase 0.0041 0.0138 0.0207
Schistosoma mansoni biogenic amine receptor 0.0028 0.0078 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0037 0.0266
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.006 0.0225 0.2077
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0028 0.0195
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0053 0.0079
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0028 0.0078 0.0117
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0034 0.0267
Schistosoma mansoni hypothetical protein 0.0053 0.0192 0.0284
Brugia malayi ORL1-like opioid receptor 0.0028 0.0078 0.0117
Echinococcus granulosus tyrosine kinase 0.0024 0.0063 0.0095
Brugia malayi bHLH-PAS transcription factor 0.004 0.0134 0.02
Brugia malayi Tyrosine-protein kinase abl-1 0.002 0.0041 0.0062
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0034 0.0105 0.0105
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0064 0.0244 0.0364
Mycobacterium ulcerans hypothetical protein 0.0027 0.0075 0.0169
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Brugia malayi Latrophilin receptor protein 2 0.0055 0.0204 0.0304
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0223 0.0553
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0012 0.0006 0.0019
Onchocerca volvulus 0.0908 0.4055 1
Trichomonas vaginalis D-aminoacylase, putative 0.0027 0.0075 0.0565
Echinococcus granulosus activin receptor type 0.0028 0.0079 0.0118
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0037 0.0266
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0023 0.0056 0.0415
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0223 0.033
Schistosoma mansoni phosphoglucomutase 0.0014 0.0017 0.0023
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0251 0.1086 0.1623
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0017
Echinococcus granulosus protein tyrosine kinase 0.0232 0.0999 0.1493
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0106 0.0431 0.0637
Schistosoma mansoni cellular tumor antigen P53 0.0036 0.0114 0.0167
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0075 0.0645
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0133 0.0554 0.0828
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0089 0.0773
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0133 0.0554 0.0828
Schistosoma mansoni intermediate filament proteins 0.002 0.0044 0.0064
Onchocerca volvulus Huntingtin homolog 0.0083 0.033 0.0814
Onchocerca volvulus Peroxidase homolog 0.0161 0.0681 0.1679
Onchocerca volvulus 0.0019 0.0037 0.0092
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0012 0.0006 0.0055
Giardia lamblia Kinase, CMGC CDK 0.0021 0.005 0.0567
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Schistosoma mansoni tyrosine kinase 0.0026 0.0069 0.0101
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0028 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0037 0.0266
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0133 0.0554 0.0828
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.0587 0.0878
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0018 0.0032 0.0229
Trypanosoma brucei cytochrome P450, putative 0.002 0.0045 0.0371
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0037 0.0048
Loa Loa (eye worm) hypothetical protein 0.006 0.0225 0.0337
Echinococcus granulosus aryl hydrocarbon receptor 0.0023 0.0056 0.0083
Brugia malayi diacylglycerol acyltransferase 0.1492 0.669 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0027 0.0073 0.0553
Echinococcus multilocularis geminin 0.0188 0.08 0.08
Echinococcus granulosus TGF beta receptor type 1 0.0053 0.0191 0.0285
Schistosoma mansoni rab6-interacting 0.0205 0.0878 0.131
Brugia malayi conserved hypotetical protein 0.0063 0.0237 0.0354
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.006 0.0225 0.0337
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0036 0.0114 0.1011
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0045 0.0371
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0742 0.5855
Onchocerca volvulus 0.0028 0.0078 0.0193
Schistosoma mansoni hypothetical protein 0.0058 0.0216 0.032
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0172 0.073 0.1844
Brugia malayi Peroxidasin 0.0164 0.0693 0.1035
Brugia malayi Dopamine receptor protein 2 0.0028 0.0078 0.0117
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.007 0.0271 0.0404
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0183 0.0273
Schistosoma mansoni loxhd1 0.0205 0.0878 0.131
Onchocerca volvulus 0.0133 0.0554 0.1366
Brugia malayi Sex muscle abnormal protein 5 0.0016 0.0026 0.0039
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0036 0.0114 0.0171
Schistosoma mansoni opsin-like receptor 0.0028 0.0078 0.0114
Schistosoma mansoni ankyrin 23/unc44 0.0047 0.0168 0.0248
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0078 0.0117
Leishmania major cytochrome p450-like protein 0.002 0.0045 0.0371
Brugia malayi nuclear receptor NHR-88 0.0133 0.0554 0.0828
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.0045 0.0371
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0014 0.0017 0.0165
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0037 0.0266
Echinococcus granulosus gamma secretase subunit aph 1 0.0296 0.1289 0.1927
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Brugia malayi Hhat protein 0.0251 0.1086 0.1623
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0066
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0078 0.0117
Echinococcus granulosus nuclear factor of activated T cells 5 0.0243 0.1051 0.1571
Onchocerca volvulus 0.0205 0.0878 0.2165
Plasmodium falciparum DNA gyrase subunit A 0.0123 0.0511 0.0756
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0034 0.0048
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0078 0.0117
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0014 0.0016 0.0155
Onchocerca volvulus 0.002 0.0044 0.0109
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0049 0.0177 0.0264
Schistosoma mansoni amine GPCR 0.0028 0.0078 0.0114
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0023 0.0056 0.0084
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0055 0.0204 0.0304
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0133 0.0554 0.0828
Echinococcus multilocularis orexin receptor type 2 0.0028 0.0078 0.0078
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0036 0.0114 0.0171
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0037 0.0122 0.155
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.002 0.0045 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0014 0.0081
Echinococcus multilocularis importin subunit beta 1 0.003 0.0089 0.0089
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0078 0.0078
Onchocerca volvulus 0.0091 0.0363 0.0894
Echinococcus multilocularis protein dispatched 1 0.0069 0.0264 0.0264
Onchocerca volvulus 0.005 0.0178 0.0438
Onchocerca volvulus 0.0036 0.0114 0.028
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0075 0.0645
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0017 0.0028 0.0213
Chlamydia trachomatis DNA gyrase subunit B 0.0059 0.0221 0.4238
Brugia malayi G-protein coupled receptor 0.0028 0.0078 0.0117
Echinococcus granulosus c src tyrosine kinase 0.002 0.0041 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0133 0.0554 0.0828
Brugia malayi larval opioid receptor 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0013
Brugia malayi hypothetical protein 0.019 0.081 0.121
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0133 0.0554 0.0828
Brugia malayi nuclear receptor RXR 0.0063 0.0237 0.0354
Mycobacterium leprae Probable lipase LipE 0.0027 0.0075 0.0169
Trypanosoma brucei glycerol uptake protein, putative 0.0251 0.1086 1
Schistosoma mansoni phosphoglucomutase 0.0014 0.0017 0.0023
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0078 0.0078
Echinococcus multilocularis fk506 binding protein 0.0023 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0083 0.0633
Schistosoma mansoni hypothetical protein 0.002 0.0045 0.0065
Schistosoma mansoni jumonji domain containing protein 0.0035 0.0112 0.0165
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0053 0.0442
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0009 0.0013
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0012 0.0009 0.0005
Loa Loa (eye worm) TOPoisomerase family member 0.0027 0.0074 0.011
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0013
Brugia malayi Nuclear hormone receptor E75 0.0063 0.0237 0.0354
Brugia malayi bZIP transcription factor family protein 0.0277 0.1205 0.1801
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0251 0.1086 0.1086
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0063 0.0236 0.0352
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0055 0.0204 0.0204
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0223 0.0545
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0045 0.0326
Mycobacterium leprae Possible regulatory protein 0.0017 0.0028 0.005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0223 0.0545
Brugia malayi Nuclear hormone receptor E75 0.0063 0.0237 0.0354
Leishmania major glycerol uptake protein, putative 0.0251 0.1086 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0131 0.1013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0017 0.0028 0.0195
Plasmodium vivax DNA gyrase subunit A, putative 0.0123 0.0511 0.0756
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0023 0.0056 0.0076
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0078 0.0078
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0063 0.0237 0.0354
Echinococcus multilocularis cyclin dependent kinase 5 0.0021 0.005 0.005
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0097 0.0393 0.0588
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0047 0.0166 0.149
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0028 0.0078 0.0117
Echinococcus granulosus tumor protein p63 0.0243 0.1049 0.1569
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0033 0.0256
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0014 0.0081
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0037 0.0056
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0053 0.0079
Onchocerca volvulus 0.0091 0.0363 0.0894
Brugia malayi nuclear hormone receptor 0.0133 0.0554 0.0828
Schistosoma mansoni tyrosine kinase 0.002 0.0041 0.0059
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0027 0.0073 0.0553
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0013 0.0014 0.0018
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0012 0.0006 0.0006
Loa Loa (eye worm) beta-lactamase 0.0027 0.0075 0.0112
Schistosoma mansoni nuclear receptor 0.0063 0.0237 0.0351
Loa Loa (eye worm) glutathione reductase 0.0051 0.0183 0.0273
Mycobacterium ulcerans DNA gyrase subunit A 0.0123 0.0511 0.1278
Brugia malayi follicle stimulating hormone receptor 0.0028 0.0078 0.0117
Onchocerca volvulus 0.0028 0.0078 0.0193
Brugia malayi steroid hormone receptor 0.0133 0.0554 0.0828
Giardia lamblia Kinase, CMGC CDK 0.0021 0.005 0.0567
Toxoplasma gondii cathepsin CPL 0.0019 0.0037 0.0048
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0037 0.0048
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0047 0.0166 0.149
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0014 0.0016 0.002
Echinococcus granulosus sex peptide receptor 0.0028 0.0078 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0133 0.0554 0.0828
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0037 0.0092
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0033 0.0256
Echinococcus granulosus o acyltransferase membrane bound domain 0.0251 0.1086 0.1623
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0023 0.0056 0.0084
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0033 0.0483
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.0033 0.0062
Entamoeba histolytica DNA topoisomerase II, putative 0.0027 0.0074 0.068
Brugia malayi G-protein coupled receptor 0.0028 0.0078 0.0117
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0028 0.0195
Onchocerca volvulus Peroxidasin homolog 0.0162 0.0686 0.1692
Echinococcus multilocularis lysosomal alpha glucosidase 0.0477 0.2107 0.2107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.0045 0.0102
Echinococcus granulosus G protein coupled receptor 139 0.0028 0.0078 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0033 0.0256
Mycobacterium tuberculosis Probable lipase LipD 0.0027 0.0075 0.0177
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0112
Schistosoma mansoni immunophilin 0.0023 0.0056 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0009 0.0046
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0045 0.0371
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0131 0.1013
Schistosoma mansoni microtubule-associated protein tau 0.1307 0.5857 0.8755
Brugia malayi Importin beta-1 subunit 0.003 0.0089 0.0133
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0133 0.0554 0.0828
Trypanosoma cruzi GUP1, putative 0.0251 0.1086 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0014 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Brugia malayi MBOAT family protein 0.0251 0.1086 0.1623
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0742 0.5855
Loa Loa (eye worm) hhat protein 0.0251 0.1086 0.1623
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0104
Schistosoma mansoni nuclear hormone receptor 0.0063 0.0237 0.0351
Loa Loa (eye worm) hypothetical protein 0.0047 0.0164 0.0245
Leishmania major protein kinase, putative 0.0018 0.0034 0.0267
Onchocerca volvulus 0.0028 0.0078 0.0193
Loa Loa (eye worm) phosphatidylinositol 3 0.0036 0.0114 0.0171
Trypanosoma brucei DNA topoisomerase ii 0.0047 0.0166 0.149
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0105 0.0157
Trypanosoma cruzi GUP1, putative 0.0251 0.1086 1
Brugia malayi nuclear hormone receptor 0.0063 0.0237 0.0354
Schistosoma mansoni hypothetical protein 0.0058 0.0216 0.032
Brugia malayi 6-phosphofructokinase 0.0065 0.0246 0.0368
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0133 0.0554 0.0828
Brugia malayi Serotonin receptor 0.0028 0.0078 0.0117
Trypanosoma brucei unspecified product 0.0015 0.0022 0.0158
Brugia malayi topoisomerase 0.0012 0.0009 0.0013
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0028 0.0078 0.0117
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0012 0.0006 0.0019
Echinococcus granulosus Polycystic kidney disease protein 0.0205 0.0878 0.1312
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0018 0.0034 0.0034
Brugia malayi hypothetical protein 0.0484 0.2137 0.3195
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0034 0.0267
Schistosoma mansoni tyrosine kinase 0.0019 0.0037 0.0053
Schistosoma mansoni phosphoglucomutase 0.0014 0.0017 0.0023
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0131 0.0196
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.002 0.0045 0.0093
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0016 0.0026 0.0036
Trichomonas vaginalis DNA topoisomerase II, putative 0.0027 0.0074 0.0557
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0742 0.5855
Brugia malayi Protein kinase domain containing protein 0.0049 0.0173 0.0259
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0065 0.0246 0.2233
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Leishmania major peptidylprolyl isomerase-like protein 0.0023 0.0056 0.047
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0134 0.0134
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0131 0.1013
Echinococcus granulosus Niemann Pick C1 protein 0.0201 0.0859 0.1285
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0018 0.0032 0.0041
Brugia malayi Protein kinase domain containing protein 0.0021 0.005 0.0075
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0133 0.0554 0.0828
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0183 0.1644
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0223 0.0223
Trichomonas vaginalis D-aminoacylase, putative 0.0027 0.0075 0.0565
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0009 0.0031
Brugia malayi Thioredoxin reductase 0.0051 0.0183 0.0273
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0567 0.0846
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0078 0.0114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Loa Loa (eye worm) hypothetical protein 0.0046 0.0161 0.0241
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0045 0.0068
Brugia malayi Cytochrome P450 family protein 0.0102 0.0416 0.0621
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0011 0.0005 0.0005
Trypanosoma brucei glucosidase, putative 0.0106 0.0431 0.3944
Echinococcus granulosus o acyltransferase membrane bound domain 0.0251 0.1086 0.1623
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0097 0.0393 0.0588
Schistosoma mansoni 6-phosphofructokinase 0.0065 0.0246 0.0366
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0078 0.0117
Giardia lamblia Fructose-bisphosphate aldolase 0.0175 0.0742 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0133 0.0554 0.0828
Trichomonas vaginalis CMGC family protein kinase 0.0021 0.005 0.0369
Echinococcus granulosus importin subunit beta 1 0.003 0.0089 0.0133
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0742 0.5855
Brugia malayi PAS domain containing protein 0.0057 0.0209 0.0312
Echinococcus granulosus fmrfamide receptor 0.0028 0.0078 0.0117
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0105 0.0157
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0033 0.0049
Loa Loa (eye worm) hypothetical protein 0.0133 0.0554 0.0828
Echinococcus granulosus lamin dm0 0.002 0.0044 0.0066
Leishmania major DNA topoisomerase ii 0.0022 0.0055 0.0458
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0251 0.1086 0.1623
Onchocerca volvulus 0.0023 0.0055 0.0136
Schistosoma mansoni jun-related protein 0.0225 0.097 0.1448
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0133 0.0554 0.0554
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0019 0.0037 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0183 0.027
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0023 0.0056 0.044
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0012 0.0009 0.0079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0037 0.0266
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.014 0.0587 0.541
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0059 0.0219 0.0536
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0251 0.1086 0.1086
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0251 0.1086 0.1086
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0033 0.0256
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Brugia malayi Animal haem peroxidase family protein 0.0161 0.0681 0.1018
Mycobacterium ulcerans proteasome PrcA 0.0882 0.3937 1
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0078 0.0114
Brugia malayi MBOAT family protein 0.0251 0.1086 0.1623
Echinococcus multilocularis snurportin 1 0.032 0.1399 0.1399
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.002 0.0045 0.0093
Giardia lamblia GTOR 0.0036 0.0114 0.1443
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Brugia malayi orphan nuclear receptor NR2E1 0.0063 0.0237 0.0354
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0133 0.0554 0.0554
Brugia malayi Cathepsin L-like precursor 0.0012 0.0009 0.0014
Schistosoma mansoni hypothetical protein 0.0049 0.0175 0.0259
Loa Loa (eye worm) hypothetical protein 0.0251 0.1086 0.1623
Plasmodium falciparum replication factor C subunit 1, putative 0.0012 0.0009 0.0005
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0027 0.0075 0.0177
Trypanosoma brucei ingi protein (ORF1) 0.0015 0.0022 0.0158
Brugia malayi Common central domain of tyrosinase family protein 0.0091 0.0363 0.0542
Schistosoma mansoni hypothetical protein 0.0225 0.097 0.1448
Schistosoma mansoni 6-phosphofructokinase 0.0065 0.0246 0.0366
Plasmodium vivax multidomain scavenger receptor, putative 0.0205 0.0878 0.1306
Brugia malayi Protein kinase domain containing protein 0.0908 0.4055 0.6061
Leishmania major fk506-binding protein 1-like protein 0.0023 0.0056 0.047
Schistosoma mansoni thyroid hormone receptor 0.0133 0.0554 0.0825
Schistosoma mansoni steroid hormone receptor ad4bp 0.0133 0.0554 0.0825
Schistosoma mansoni hypothetical protein 0.0055 0.0204 0.0302
Trypanosoma cruzi glycerol uptake protein, putative 0.0251 0.1086 1
Trichomonas vaginalis conserved hypothetical protein 0.0251 0.1086 0.8583
Brugia malayi Pax transcription activation domain interacting protein 0.0012 0.0009 0.0013
Brugia malayi ecdysone receptor 0.0063 0.0237 0.0354
Loa Loa (eye worm) MBOAT family protein 0.0251 0.1086 0.1623
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0105 0.0105
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0016 0.0026 0.0192
Loa Loa (eye worm) hypothetical protein 0.007 0.0271 0.0404
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0033 0.0483
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0133 0.0554 0.0828
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0073 0.011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0037 0.0266
Schistosoma mansoni RAR-like nuclear receptor 0.0133 0.0554 0.0825
Loa Loa (eye worm) TK protein kinase 0.0024 0.0063 0.0095
Brugia malayi Serotonin receptor 0.0028 0.0078 0.0117
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.0045 0.0371
Loa Loa (eye worm) SRC-1 0.0034 0.0105 0.0157
Trichomonas vaginalis CMGC family protein kinase 0.0021 0.005 0.0369
Trichomonas vaginalis alpha-glucosidase, putative 0.0106 0.0431 0.3393
Leishmania major phosphopantetheinyl transferase-like protein 0.0014 0.0016 0.0103
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0029 0.0084 0.0725
Onchocerca volvulus 0.0027 0.0075 0.0185
Schistosoma mansoni amine GPCR 0.0028 0.0078 0.0114
Trypanosoma cruzi cdc2-related kinase 3 0.0021 0.005 0.0416
Brugia malayi jmjC domain containing protein 0.0035 0.0112 0.0167
Onchocerca volvulus 0.0161 0.0681 0.1679
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0018 0.0032 0.0476
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0078 0.0117
Echinococcus multilocularis RUN 0.0205 0.0878 0.0878
Brugia malayi GnHR receptor homolog 0.0028 0.0078 0.0117
Schistosoma mansoni neuropeptide receptor 0.0028 0.0078 0.0114
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0078 0.0117
Brugia malayi RNA binding protein 0.0136 0.0567 0.0848
Leishmania major ATP-dependent phosphofructokinase 0.0065 0.0246 0.2233
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0032 0.0229
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0246 0.1926
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.005 0.0178 0.0265
Trypanosoma cruzi glycerol uptake protein, putative 0.0251 0.1086 1
Echinococcus granulosus cathepsin l1 0.0012 0.0009 0.0014
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0017 0.0028 0.0213
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0251 0.1086 1
Brugia malayi Cathepsin L-like precursor 0.0019 0.0037 0.0056
Schistosoma mansoni hypothetical protein 0.032 0.1399 0.2089
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0106 0.0431 0.3393
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0034 0.0108 0.0154
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0012 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0063 0.0237 0.0237
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.002 0.0045 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0028 0.0195
Onchocerca volvulus 0.0028 0.0078 0.0193
Schistosoma mansoni retinoic acid receptor RXR 0.0242 0.1048 0.1564
Onchocerca volvulus Peroxidase homolog 0.0161 0.0681 0.1679
Echinococcus multilocularis beta LACTamase domain containing family member 0.0027 0.0075 0.0075
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0022 0.0055 0.0458
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.002 0.0045 0.0093
Brugia malayi DKFZp564C0469 protein 0.0012 0.0009 0.0013
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0028 0.0078 0.0114
Brugia malayi Death domain containing protein 0.0047 0.0168 0.025
Schistosoma mansoni biogenic amine receptor 0.0028 0.0078 0.0114
Onchocerca volvulus 0.0027 0.0075 0.0185
Brugia malayi hypothetical protein 0.0012 0.0009 0.0013
Echinococcus granulosus arachidonate 5 lipoxygenase 0.1097 0.4908 0.7337
Brugia malayi Niemann-Pick C1 protein precursor 0.014 0.0587 0.0878
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0053 0.0053
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.0271 0.0404
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0078 0.0114
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0053 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0742 0.5855
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0078 0.0078
Brugia malayi Uncoordinated protein 44 0.0047 0.0168 0.025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0034 0.0048
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0223 0.0333
Echinococcus granulosus neuropeptide receptor 0.0028 0.0078 0.0117
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0033 0.0041
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.002 0.0042 0.0042
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.0026 0.0036
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0183 0.0273
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0078 0.0114
Brugia malayi hypothetical protein 0.007 0.0271 0.0404
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0028 0.0078 0.0193
Plasmodium falciparum glutathione reductase 0.0018 0.0033 0.0041
Echinococcus granulosus tar DNA binding protein 0.0136 0.0567 0.0848
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0011 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.1241 0.5558 0.8307
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0013 0.0014 0.0079
Brugia malayi nuclear hormone receptor family member odr-7 0.0063 0.0237 0.0354
Brugia malayi Dopamine receptor protein 1 0.0028 0.0078 0.0117
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0105 0.0105
Echinococcus granulosus single minded 2 0.004 0.0134 0.02
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0076 0.0571
Loa Loa (eye worm) blistered cuticle protein 3 0.0161 0.0681 0.1018
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0123 0.0511 1
Trypanosoma brucei Aph-1 protein, putative 0.0115 0.0474 0.4338
Trichomonas vaginalis maltase-glucoamylase, putative 0.0106 0.0431 0.3393
Brugia malayi hypothetical protein 0.0063 0.0237 0.0354
Echinococcus granulosus g-protein coupled receptor 0.0028 0.0078 0.0117
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0133 0.0554 0.0828
Brugia malayi Cytochrome P450 family protein 0.002 0.0045 0.0068
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.0133 0.0554 0.0828
Echinococcus granulosus neuropeptide FF receptor 2 0.0028 0.0078 0.0117
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0246 0.1926
Brugia malayi ShTK domain containing protein 0.0091 0.0363 0.0542
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.007 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0017
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0078 0.0078
Brugia malayi Furin-like cysteine rich region family protein 0.0051 0.0186 0.0278
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0063 0.0237 0.0351
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0251 0.1086 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0124 0.0515 0.0769
Schistosoma mansoni tyrosine kinase 0.002 0.0041 0.0059
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0075 0.0645
Brugia malayi sulfakinin receptor protein 0.0028 0.0078 0.0117
Echinococcus multilocularis cyclin dependent kinase 1 0.0021 0.005 0.005
Loa Loa (eye worm) glutaminase 2 0.029 0.1264 0.189
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Giardia lamblia Ribonuclease H 0.0014 0.0017 0.0113
Loa Loa (eye worm) TK/FAK protein kinase 0.0234 0.1011 0.1512
Brugia malayi Hint module family protein 0.0047 0.0164 0.0245
Brugia malayi glutaminase DH11.1 0.029 0.1264 0.189
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0078 0.0117
Echinococcus granulosus NCK adaptor protein 0.0016 0.0026 0.0039
Schistosoma mansoni patched 1 0.006 0.0225 0.0334
Echinococcus granulosus cyclin dependent kinase 0.0021 0.005 0.0075
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0029 0.0084 0.0725
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0133 0.0554 0.0554
Echinococcus multilocularis expressed conserved protein 0.0132 0.0549 0.0549
Onchocerca volvulus 0.0091 0.0363 0.0894
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0047 0.0168 0.025
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0065 0.0246 0.2209
Brugia malayi Cathepsin L-like precursor 0.0019 0.0037 0.0056
Mycobacterium leprae Conserved hypothetical protein 0.002 0.0045 0.0093
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0078 0.0114
Schistosoma mansoni alpha-1 adrenergic receptor 0.0028 0.0078 0.0114
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0018 0.0032 0.0222
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.0045 0.0102
Leishmania major glycerol uptake protein, putative 0.0251 0.1086 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0018 0.0034 0.0048
Brugia malayi Variant SH3 domain containing protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0009 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.0045 0.0102
Entamoeba histolytica hypothetical protein 0.0049 0.0175 0.1611
Trichomonas vaginalis glutaminase, putative 0.029 0.1264 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0136 0.0567 0.0848
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0078 0.0078
Echinococcus multilocularis Niemann Pick C1 protein 0.0201 0.0859 0.0859
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0063 0.0472
Brugia malayi hypothetical protein 0.007 0.0271 0.0404
Schistosoma mansoni DNA topoisomerase II 0.0027 0.0074 0.0108
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Loa Loa (eye worm) hypothetical protein 0.0133 0.0554 0.0828
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0097 0.0393 0.0393
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0016 0.0026 0.0039
Trypanosoma brucei trypanothione reductase 0.0051 0.0183 0.1644
Entamoeba histolytica phosphofructokinase, putative 0.0065 0.0246 0.227
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0133 0.0554 0.0554
Toxoplasma gondii ABC1 family protein 0.0027 0.0075 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0037 0.0092
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0078 0.0117
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0112 0.0165
Brugia malayi Cytochrome P450 family protein 0.002 0.0045 0.0068
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0021 0.0048 0.0048
Onchocerca volvulus 0.0099 0.0399 0.0983
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0133 0.0554 0.0825
Mycobacterium ulcerans esterase/lipase LipP 0.0027 0.0075 0.0169
Echinococcus multilocularis G-protein coupled receptor, putative 0.0028 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0112 0.0112
Echinococcus granulosus tyrosine protein kinase Src42A 0.0021 0.0048 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0078 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0078 0.0078
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0011 0.0005 0.0005
Trichomonas vaginalis penicillin-binding protein, putative 0.0027 0.0075 0.0565
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0013 0.0014 0.0021
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0023 0.0056 0.0515
Echinococcus granulosus lamin 0.002 0.0044 0.0066
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0175 0.0744 0.1113
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0075 0.0293 0.2663
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0063 0.0237 0.0354
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0045 0.0068
Plasmodium falciparum LCCL domain-containing protein 0.0205 0.0878 0.1306
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0089 0.0773
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.0045 0.006
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0567 0.0846
Echinococcus granulosus neuropeptide receptor 0.0028 0.0078 0.0117
Mycobacterium tuberculosis Probable dehydrogenase 0.0116 0.0477 0.12
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0035 0.0112 0.0167
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0027 0.0075 0.0177
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0183 0.0273
Brugia malayi RE15519p 0.0028 0.0078 0.0117
Entamoeba histolytica hypothetical protein 0.0049 0.0175 0.1611
Echinococcus granulosus TGF-beta receptor type-1 0.0053 0.0191 0.0285
Echinococcus granulosus serotonin receptor 0.0028 0.0078 0.0117
Loa Loa (eye worm) ShTK domain-containing protein 0.0091 0.0363 0.0542
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0055 0.0201 0.03
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0091 0.0363 0.0542
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.002 0.0042 0.0062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0251 0.1086 0.1086
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0028 0.0078 0.0114
Entamoeba histolytica protein kinase, putative 0.0017 0.0032 0.0297
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0014 0.0016 0.0072
Echinococcus granulosus death domain containing protein 0.0047 0.0168 0.025
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.002 0.0045 0.0093
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0027 0.0073 0.0631
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.1492 0.669 1
Leishmania major cathepsin L-like protease 0.0071 0.0273 0.2479
Schistosoma mansoni tyrosine kinase 0.0053 0.0194 0.0288
Echinococcus granulosus ecdysone induced protein 78C 0.0133 0.0554 0.0828
Echinococcus granulosus GPCR family 2 0.0055 0.0204 0.0304
Echinococcus multilocularis nuclear receptor nhr 48 0.0063 0.0237 0.0237
Loa Loa (eye worm) animal heme peroxidase 0.0161 0.0681 0.1018
Onchocerca volvulus Protein ultraspiracle homolog 0.0133 0.0554 0.1366
Echinococcus granulosus nibrin 0.0012 0.0009 0.0013
Brugia malayi phosphofructokinase 0.0065 0.0246 0.0368
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0036 0.0114 0.1011
Loa Loa (eye worm) intermediate filament protein 0.002 0.0044 0.0066
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0184 0.0275
Echinococcus granulosus g protein coupled receptor 0.0028 0.0078 0.0117
Giardia lamblia DNA topoisomerase II 0.0025 0.0065 0.0775
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0045 0.0325
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0078 0.0117
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) TAR-binding protein 0.0136 0.0567 0.0848
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0078 0.0078
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0205 0.1845
Onchocerca volvulus 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Schistosoma mansoni myosin xvIII 0.0028 0.0078 0.0114
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0017 0.0029 0.0029
Brugia malayi Cathepsin L-like precursor 0.0019 0.0037 0.0056
Echinococcus granulosus dro:myosuppressin receptor 0.0028 0.0078 0.0117
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.0045 0.0102
Loa Loa (eye worm) hypothetical protein 0.0205 0.0878 0.1312
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0035 0.0109 0.1007
Loa Loa (eye worm) hypothetical protein 0.0048 0.0169 0.0253
Schistosoma mansoni alpha-glucosidase 0.0411 0.1808 0.27
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0116 0.0477 0.12
Loa Loa (eye worm) hypothetical protein 0.0083 0.033 0.0493
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0055 0.0204 0.0304
Brugia malayi putative neuropeptide receptor 0.0028 0.0078 0.0117
Schistosoma mansoni transcription factor LCR-F1 0.0049 0.0175 0.0259
Brugia malayi Glycosyl hydrolases family 31 protein 0.0106 0.0431 0.0645
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.002 0.0045 0.0093
Loa Loa (eye worm) hypothetical protein 0.0251 0.1086 0.1623
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0183 0.0273
Onchocerca volvulus 0.0142 0.0594 0.1465
Schistosoma mansoni immunophilin 0.0023 0.0056 0.0081
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0014 0.0016 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0028 0.0195
Mycobacterium tuberculosis Probable oxidoreductase 0.0129 0.0535 0.1349
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0009 0.0039
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0012 0.0006 0.0019
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0012 0.0018
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0063 0.0236 0.0236
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0009 0.0039
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0028 0.0078 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0742 0.5855
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0009 0.0014
Brugia malayi cytoplasmic intermediate filament protein 0.0011 0.0002 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0032 0.0229
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0011 0.0005 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0033 0.0256
Onchocerca volvulus 0.0028 0.0078 0.0193
Leishmania major cathepsin L-like protease 0.0019 0.0037 0.0296
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0106 0.0431 0.0645
Echinococcus granulosus sterol O acyltransferase 1 0.0251 0.1086 0.1623
Echinococcus granulosus tyrosine protein kinase Blk 0.0024 0.0063 0.0095
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0029 0.0085 0.0127
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0049 0.0175 0.0261
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0019 0.004 0.0431
Leishmania major ribonuclease H1, putative 0.0014 0.0017 0.0108
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0034 0.0267
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0246 0.1926
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0273 0.2479
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Echinococcus multilocularis 0.002 0.0045 0.0045
Echinococcus granulosus peroxidasin 0.0164 0.0693 0.1035
Schistosoma mansoni hypothetical protein 0.0028 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.0039 0.0131 0.0196
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Echinococcus multilocularis growth factor receptor bound protein 2 0.0016 0.0026 0.0026
Echinococcus multilocularis serotonin receptor 0.0028 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0034 0.0051
Echinococcus multilocularis cysteine protease 0.0019 0.0037 0.0037
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.0514 0.0768
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0078 0.0114
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0028 0.0078 0.0114
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0033 0.0041
Leishmania major cathepsin L-like protease 0.0019 0.0037 0.0296
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.005 0.0178 0.0263
Onchocerca volvulus 0.0018 0.0034 0.0083
Brugia malayi beta-lactamase family protein 0.0027 0.0075 0.0112
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0033 0.0256
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0036 0.0114 0.0168
Brugia malayi Cathepsin L-like precursor 0.0019 0.0037 0.0056
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0017 0.0028 0.0213
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.0045 0.0102
Trypanosoma cruzi cdc2-related kinase 1 0.0021 0.005 0.0416
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0431 0.3944
Echinococcus granulosus microtubule associated protein 2 0.1307 0.5857 0.8756
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.0026 0.0036
Entamoeba histolytica hypothetical protein 0.0049 0.0175 0.1611
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0023 0.0056 0.047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Trypanosoma brucei glycerol uptake protein, putative 0.0251 0.1086 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.0623 0.0931
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0023 0.0056 0.0646
Echinococcus granulosus insulin receptor 0.0019 0.0037 0.0056
Loa Loa (eye worm) hypothetical protein 0.0251 0.1086 0.1623
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0184 0.0184
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.0033 0.0331
Echinococcus granulosus nuclear receptor nhr 48 0.0063 0.0237 0.0354
Brugia malayi MH2 domain containing protein 0.0124 0.0514 0.0768
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0053 0.0395
Brugia malayi isocitrate dehydrogenase 0.0011 0.0005 0.0008
Echinococcus granulosus lysosomal alpha glucosidase 0.0477 0.2107 0.315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0076 0.0571
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0032 0.0229
Echinococcus granulosus Nuclear hormone receptor HR96 0.0063 0.0237 0.0354
Toxoplasma gondii ATPase, AAA family protein 0.0012 0.0009 0.0005
Schistosoma mansoni hypothetical protein 0.0055 0.0204 0.0302
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0065 0.0246 0.2233
Echinococcus granulosus g protein coupled receptor 0.0028 0.0078 0.0117
Brugia malayi RNase H family protein 0.0014 0.0017 0.0025
Schistosoma mansoni growth hormone secretagogue receptor 0.0028 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0013
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0034 0.0267
Brugia malayi bone morphogenetic protein type 1 receptor 0.0055 0.0201 0.03
Brugia malayi 6-phosphofructokinase 0.0065 0.0246 0.0368
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0105 0.0105
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0055 0.0204 0.0204
Echinococcus multilocularis lipoxygenase domain containing protein 0.0205 0.0878 0.0878
Entamoeba histolytica hypothetical protein 0.006 0.0225 0.2077
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0033 0.0256
Schistosoma mansoni tyrosine kinase 0.0034 0.0105 0.0154
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0028 0.0195
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0078 0.0078
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0018 0.0032 0.0326
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.002 0.0045 0.0093
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.0009 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0078 0.0117
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0028 0.0078 0.0117
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0027 0.0074 0.011
Loa Loa (eye worm) TK/EGFR protein kinase 0.0051 0.0186 0.0278
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0056 0.047
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0023 0.0056 0.0056
Plasmodium vivax glutathione reductase, putative 0.0051 0.0183 0.0266
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0083 0.0633
Echinococcus granulosus tyrosine protein kinase Src64B 0.0034 0.0105 0.0157
Echinococcus multilocularis gamma secretase subunit aph 1 0.0296 0.1289 0.1289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0133 0.0554 0.0828
Schistosoma mansoni gamma-secretase subunit aph-1 0.0296 0.1289 0.1925
Echinococcus multilocularis protein kinase 0.0041 0.0138 0.0138
Leishmania major cytochrome p450-like protein 0.002 0.0045 0.0371
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0045 0.0371
Echinococcus multilocularis sterol regulatory element binding protein 0.006 0.0225 0.0225
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Onchocerca volvulus 0.0276 0.1199 0.2958
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0028 0.0078 0.0078
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0251 0.1086 0.162
Echinococcus multilocularis insulin receptor 0.0019 0.0037 0.0037
Brugia malayi Glycosyl hydrolases family 31 protein 0.0477 0.2107 0.315
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0036 0.0114 0.1011
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.0045 0.0102
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0023 0.0056 0.0646
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0013 0.0014 0.0021
Trichomonas vaginalis transmembrane protein nessy, putative 0.0251 0.1086 0.8583
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0018 0.0032 0.0299
Onchocerca volvulus Huntingtin homolog 0.0083 0.033 0.0814
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0106 0.0431 0.3393
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0014 0.0081
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0012 0.0006 0.0055
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0047 0.0167 0.025
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.0514 0.0768
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0078 0.0117
Echinococcus granulosus beta LACTamase domain containing family member 0.0027 0.0075 0.0112
Schistosoma mansoni protein kinase 0.0053 0.0191 0.0283
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0036 0.0114 0.1011
Schistosoma mansoni ran 0.0022 0.0053 0.0076
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0091 0.0363 0.0542
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0009 0.0031
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0009 0.0039
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0063 0.0237 0.0237
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0033 0.0256
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0114 0.0879
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0015 0.0022 0.0158
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0023 0.0056 0.0415
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0277 0.1205 0.1205
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0183 0.0273
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0091 0.0363 0.0542
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0183 0.027
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0052 0.019 0.1475
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0116 0.0477 0.12
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0089 0.0125
Schistosoma mansoni survival motor neuron protein 0.0099 0.0399 0.0594
Brugia malayi AKH receptor 0.0028 0.0078 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0014 0.0081
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Chlamydia trachomatis DNA gyrase subunit A 0.0013 0.0011 0.0051
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0012 0.0006 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.005 0.0072
Loa Loa (eye worm) 6-phosphofructokinase 0.0065 0.0246 0.0368
Leishmania major cathepsin L-like protease 0.0071 0.0273 0.2479
Entamoeba histolytica vacuolar protein sorting 26 0.0251 0.1086 1
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.001 0.0012
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0078 0.0078
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0133 0.0554 0.0825
Schistosoma mansoni peroxidasin 0.0161 0.0681 0.1015
Loa Loa (eye worm) hypothetical protein 0.0091 0.0363 0.0542
Echinococcus granulosus snurportin 1 0.032 0.1399 0.2091
Loa Loa (eye worm) nuclear receptor NHR-67 0.0063 0.0237 0.0354
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0021 0.005 0.0416
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0078 0.0114
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0133 0.0554 0.1366
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0027 0.0075 0.0112
Echinococcus granulosus g protein coupled receptor 0.0028 0.0078 0.0117
Onchocerca volvulus Netrin receptor homolog 0.0049 0.0173 0.0426
Loa Loa (eye worm) STAT protein 0.0102 0.0415 0.0621
Treponema pallidum alginate O-acetylation protein (algI) 0.0251 0.1086 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0083 0.0633
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0021 0.005 0.0075
Echinococcus multilocularis epidermal growth factor receptor 0.0051 0.0186 0.0186
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0078 0.0078
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0105 0.0157
Echinococcus granulosus smoothened 0.0151 0.0637 0.0952
Echinococcus granulosus tachykinin peptides receptor 99D 0.0028 0.0078 0.0117
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0245 0.2222
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.002 0.0045 0.0093
Mycobacterium tuberculosis Probable hydrolase 0.0027 0.0075 0.0177
Entamoeba histolytica hypothetical protein 0.0049 0.0175 0.1611
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0013 0.0014 0.0079
Echinococcus multilocularis serotonin receptor 0.0028 0.0078 0.0078
Toxoplasma gondii DNA topoisomerase 2, putative 0.0027 0.0074 0.0103
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.0045 0.0102
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0112
Loa Loa (eye worm) hypothetical protein 0.0044 0.0151 0.0226
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0078 0.0114
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.0045 0.0102
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0251 0.1086 0.162
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0567 0.0846
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0012 0.0018
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.0045 0.0102
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0028 0.0078 0.0078
Schistosoma mansoni tyrosine kinase 0.0034 0.0105 0.0154
Brugia malayi photoreceptor-specific nuclear receptor 0.0133 0.0554 0.0828
Echinococcus multilocularis neutral alpha glucosidase AB 0.0106 0.0431 0.0431
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0023 0.0056 0.0084
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0039 0.0131 0.1167
Brugia malayi G protein-coupled receptor 0.0028 0.0078 0.0117
Trichomonas vaginalis penicillin-binding protein, putative 0.0027 0.0075 0.0565
Loa Loa (eye worm) hhat protein 0.0251 0.1086 0.1623
Brugia malayi hypothetical protein 0.0049 0.0175 0.0261
Echinococcus granulosus peptide allatostatin:somatostatin 0.0028 0.0078 0.0117
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0133 0.0554 0.0828
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0078 0.0117
Trichomonas vaginalis immunophilin, putative 0.0023 0.0056 0.0415
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0078 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0251 0.1086 0.8583
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0045 0.0326
Brugia malayi Animal haem peroxidase family protein 0.0161 0.0681 0.1018
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0296 0.1289 0.1927
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0028 0.0078 0.0117
Brugia malayi intermediate filament protein 0.002 0.0044 0.0066
Echinococcus multilocularis aryl hydrocarbon receptor 0.0023 0.0056 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0009 0.0039
Echinococcus granulosus netrin receptor unc 5 0.0049 0.0174 0.026
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0023 0.0056 0.047
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0027 0.0075 0.0112
Entamoeba histolytica phosphofructokinase, putative 0.0065 0.0246 0.227
Loa Loa (eye worm) animal heme peroxidase 0.0162 0.0686 0.1025
Onchocerca volvulus 0.0251 0.1086 0.2677
Schistosoma mansoni tyrosine kinase 0.0051 0.0186 0.0275
Loa Loa (eye worm) IKK protein kinase 0.0908 0.4055 0.6061
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0075 0.0293 0.0438
Brugia malayi neuropeptide F receptor 0.0028 0.0078 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0225 0.1759
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0018 0.0035 0.0272
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0097 0.0393 0.0586
Schistosoma mansoni hypothetical protein 0.012 0.0494 0.0736
Schistosoma mansoni lamin 0.002 0.0044 0.0064
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0123 0.0511 0.1286
Echinococcus multilocularis 0.0015 0.0021 0.0021
Echinococcus multilocularis sterol O acyltransferase 1 0.0251 0.1086 0.1086
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0028 0.0078 0.0114
Treponema pallidum fructose-bisphosphate aldolase 0.0175 0.0742 0.6807
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0133 0.0554 0.0825
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0033 0.0256
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0056
Leishmania major phosphatidylinositol 3-kinase, putative 0.0013 0.0014 0.0079
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0133 0.0554 0.0554
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.1492 0.669 0.669
Schistosoma mansoni protein kinase 0.0027 0.0073 0.0107
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0011 0.0005 0.0005
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0016 0.0103
Toxoplasma gondii target of rapamycin (TOR), putative 0.0027 0.0076 0.0105
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0014 0.0016 0.002
Echinococcus granulosus 7TM GPCR rhodopsin 0.0028 0.0078 0.0117
Trichomonas vaginalis D-aminoacylase, putative 0.0027 0.0075 0.0565
Chlamydia trachomatis DNA gyrase subunit A 0.0123 0.0511 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0271 0.0404
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0175 0.0742 0.6832
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Leishmania major cathepsin L-like protease 0.0019 0.0037 0.0296
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0049 0.0177 0.0177
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0028 0.0078 0.0078
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0075 0.0293 0.2663
Loa Loa (eye worm) hypothetical protein 0.0133 0.0554 0.0828
Onchocerca volvulus 0.004 0.0134 0.0331
Trichomonas vaginalis ribonuclease H1, putative 0.0014 0.0017 0.0105
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0027 0.0075 0.0169
Onchocerca volvulus 0.0019 0.0037 0.0092
Echinococcus granulosus hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0133 0.0554 0.0828
Schistosoma mansoni hypothetical protein 0.0188 0.08 0.1194
Schistosoma mansoni lipoxygenase 0.1097 0.4908 0.7337
Brugia malayi hypothetical protein 0.0063 0.0237 0.0354
Loa Loa (eye worm) phosphofructokinase 0.0065 0.0246 0.0368
Onchocerca volvulus 0.0205 0.0878 0.2165
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0078 0.0078
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0027 0.0075 0.0109
Onchocerca volvulus Ribonuclease H1 homolog 0.0014 0.0017 0.0042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0037 0.0266
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0024 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.007 0.0271 0.0404
Onchocerca volvulus 0.0028 0.0078 0.0193
Echinococcus multilocularis thyroid hormone receptor alpha 0.0133 0.0554 0.0554
Schistosoma mansoni hypothetical protein 0.0188 0.08 0.1194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0053 0.0395
Onchocerca volvulus 0.0028 0.0078 0.0193
Onchocerca volvulus Bile acid receptor homolog 0.0133 0.0554 0.1366
Loa Loa (eye worm) tyrosinase 1 0.0091 0.0363 0.0542
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0047 0.0168 0.0168
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.002 0.0045 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0037 0.0266
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.0045 0.0102
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0013 0.0014 0.0079
Trichomonas vaginalis fk506-binding protein, putative 0.0023 0.0056 0.0415
Echinococcus multilocularis Zinc finger, PHD finger 0.0012 0.0006 0.0006
Mycobacterium tuberculosis Probable esterase LipL 0.0027 0.0075 0.0177
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0399 0.0596
Plasmodium falciparum glutathione reductase 0.0051 0.0183 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0133 0.0554 0.0828
Schistosoma mansoni hypothetical protein 0.0205 0.0878 0.131
Brugia malayi cathepsin L-like precursor 0.0012 0.0009 0.0014
Schistosoma mansoni nuclear hormone receptor 0.0133 0.0554 0.0825
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0028 0.0078 0.0078
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0027 0.0074 0.0182
Leishmania major glycerol uptake protein, putative 0.0251 0.1086 1
Entamoeba histolytica hypothetical protein 0.0024 0.0063 0.0581
Trypanosoma cruzi target of rapamycin kinase 3 0.0029 0.0084 0.0725
Leishmania major cathepsin L-like protease 0.0019 0.0037 0.0296
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0078 0.0114
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0017 0.0031 0.0046
Plasmodium falciparum DNA topoisomerase 2 0.0027 0.0074 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0078 0.0114
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.0045 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0133 0.0554 0.0828
Entamoeba histolytica hypothetical protein 0.0251 0.1086 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Echinococcus multilocularis neuropeptide s receptor 0.0028 0.0078 0.0078
Leishmania major hypothetical protein, conserved 0.0251 0.1086 1
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0023 0.0056 0.0084
Echinococcus granulosus 7tm_1 domain containing protein 0.0028 0.0078 0.0117
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0033 0.0256
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0251 0.1086 0.162
Brugia malayi activin receptor:ISOTYPE=IIA. 0.0039 0.0129 0.0193
Treponema pallidum NADH oxidase 0.0018 0.0033 0.0225
Brugia malayi Steroid receptor seven-up type 2 0.0133 0.0554 0.0828
Brugia malayi neuropeptide F receptor 0.0028 0.0078 0.0117
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0063 0.0237 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0009 0.0039
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0055 0.0204 0.0304
Echinococcus granulosus cathepsin l1 0.0019 0.0037 0.0056
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0012 0.0006 0.0001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0028 0.0078 0.0117
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0034 0.0105 0.0105
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0037 0.0056
Brugia malayi STAT protein, DNA binding domain containing protein 0.0102 0.0415 0.0621
Echinococcus granulosus epidermal growth factor receptor 0.0029 0.0085 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0251 0.1086 0.8583
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.007 0.0271 0.0402
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0021 0.005 0.0416
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.0083 0.033 0.0493
Loa Loa (eye worm) hypoxia-induced factor 1 0.0167 0.0708 0.1058
Schistosoma mansoni zinc finger protein 0.0251 0.1086 0.162
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0112 0.0167
Echinococcus multilocularis isocitrate dehydrogenase 0.0011 0.0005 0.0005
Echinococcus multilocularis Polycystic kidney disease protein 0.0205 0.0878 0.0878
Onchocerca volvulus 0.0063 0.0237 0.0583
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0028 0.0078 0.0114
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0112 0.0167
Brugia malayi hypothetical protein 0.0218 0.0936 0.1399
Schistosoma mansoni glutaminase 0.029 0.1264 0.1888
Loa Loa (eye worm) hypothetical protein 0.003 0.0089 0.0133
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0033 0.0041
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0078 0.0078
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0078 0.0078
Toxoplasma gondii ribonuclease HI protein 0.0014 0.0017 0.0017
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.014 0.0583 0.0583
Schistosoma mansoni lamin 0.002 0.0044 0.0064
Echinococcus multilocularis cyclin dependent kinase 0.0021 0.005 0.005
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0075 0.0293 0.2698
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0205 0.0306
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0013
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0123 0.0511 0.4663
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.1492 0.669 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0028 0.0078 0.0117
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0106 0.0431 0.3973
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.005 0.0072
Schistosoma mansoni adenoreceptor 0.0028 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.014 0.0587 0.0878
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0024 0.0063 0.0095
Onchocerca volvulus 0.0028 0.0078 0.0193
Echinococcus multilocularis jun protein 0.0277 0.1205 0.1205
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0037 0.0037
Echinococcus granulosus orexin receptor type 2 0.0028 0.0078 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0014 0.0081
Trypanosoma brucei cdc2-related kinase 1 0.0021 0.005 0.0416
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0009 0.0039
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0033 0.0041
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0446 0.1966 0.2937
Loa Loa (eye worm) hypothetical protein 0.007 0.0271 0.0404
Brugia malayi hypothetical protein 0.0205 0.0878 0.1312
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0018 0.0032 0.0041
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0017 0.0028 0.0195
Mycobacterium ulcerans glutaminase 0.029 0.1264 0.3196
Loa Loa (eye worm) hypothetical protein 0.0624 0.2772 0.4144
Echinococcus granulosus epidermal growth factor receptor 0.0051 0.0186 0.0278
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0022 0.0158
Loa Loa (eye worm) 6-phosphofructokinase 0.0065 0.0246 0.0368
Schistosoma mansoni adapter molecule crk 0.0016 0.0026 0.0036
Schistosoma mansoni single-minded 0.0057 0.0209 0.0309
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0277 0.1205 0.1801
Mycobacterium ulcerans lipase LipD 0.0027 0.0075 0.0169
Loa Loa (eye worm) animal heme peroxidase 0.0161 0.0681 0.1018
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0243 0.1051 0.1051
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0183 0.0452
Leishmania major cathepsin L-like protease 0.0071 0.0273 0.2479
Brugia malayi protein C17H12.11 0.0046 0.0161 0.0241
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0045 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.0021 0.005 0.0369
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0131 0.1013
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0032 0.0229
Echinococcus multilocularis cyclin dependent kinase 1 0.0021 0.005 0.005
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0033 0.0256
Echinococcus multilocularis allatostatin A receptor 0.0028 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0037 0.0266
Brugia malayi hypothetical protein 0.0205 0.0878 0.1312
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0882 0.3937 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0033 0.0256
Trypanosoma cruzi FHA domain containing protein, putative 0.0012 0.0009 0.0031
Brugia malayi hypoxia-induced factor 1 0.0167 0.0708 0.1058
Brugia malayi CHE-14 protein 0.006 0.0225 0.0337
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Schistosoma mansoni peroxidasin 0.0163 0.0687 0.1025
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0063 0.0237 0.0583
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0078 0.0117
Schistosoma mansoni hypothetical protein 0.0047 0.0168 0.0248
Mycobacterium leprae conserved hypothetical protein 0.0027 0.0075 0.0169
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Onchocerca volvulus 0.0218 0.0936 0.2309
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0076 0.0571
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0012 0.0006 0.0001
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0251 0.1086 0.162
Brugia malayi Isocitrate dehydrogenase 0.0011 0.0005 0.0008
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.002 0.0045 0.0093
Entamoeba histolytica Ran family GTPase 0.0022 0.0053 0.0488
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0012 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0078 0.0078
Echinococcus multilocularis musashi 0.002 0.0044 0.0044
Echinococcus multilocularis lysosomal alpha glucosidase 0.0477 0.2107 0.2107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0037 0.0266
Onchocerca volvulus 0.0012 0.0009 0.0023
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0063 0.0472
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0076 0.0571
Plasmodium falciparum thioredoxin reductase 0.0018 0.0033 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0078 0.0114
Treponema pallidum ribonuclease H (rnhA) 0.0014 0.0017 0.0077
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Echinococcus multilocularis tyrosine protein kinase Srms 0.0024 0.0063 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0183 0.027
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0059 0.0221 0.4238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) TYRA-2 protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0078 0.0117
Echinococcus granulosus o acyltransferase membrane bound domain 0.0251 0.1086 0.1623
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.002 0.0045 0.0093
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0105 0.0157
Loa Loa (eye worm) DR-78 0.0063 0.0237 0.0354
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0133 0.0554 0.0828
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0027 0.0074 0.011
Loa Loa (eye worm) hypothetical protein 0.0047 0.0168 0.025
Brugia malayi Cathepsin L-like precursor 0.0019 0.0037 0.0056
Onchocerca volvulus 0.0161 0.0681 0.1679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0083 0.0633
Loa Loa (eye worm) voltage-gated potassium channel 0.0096 0.0386 0.0577
Leishmania major hypothetical protein, conserved 0.0027 0.0075 0.0645
Schistosoma mansoni hypothetical protein 0.0099 0.0399 0.0594
Brugia malayi hypothetical protein 0.0046 0.0161 0.0241
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0033 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0567 0.0846
Loa Loa (eye worm) RNA binding protein 0.0136 0.0567 0.0848
Echinococcus multilocularis peroxidasin 0.0164 0.0693 0.0693
Onchocerca volvulus 0.0028 0.0078 0.0193
Echinococcus multilocularis lamin dm0 0.002 0.0044 0.0044
Brugia malayi Animal haem peroxidase family protein 0.0161 0.0681 0.1018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0028 0.0078 0.0078
Onchocerca volvulus 0.0019 0.0037 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.0045 0.0102
Mycobacterium ulcerans beta-lactamase 0.0027 0.0075 0.0169
Trichomonas vaginalis alpha-glucosidase, putative 0.0106 0.0431 0.3393
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0065 0.0246 0.0614
Mycobacterium ulcerans 6-phosphofructokinase 0.0065 0.0246 0.0606
Brugia malayi Doublecortin family protein 0.0205 0.0878 0.1312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Echinococcus multilocularis lipoxygenase domain containing protein 0.0205 0.0878 0.0878
Schistosoma mansoni retinoid-x-receptor (RXR) 0.007 0.0271 0.0402
Schistosoma mansoni hypothetical protein 0.0055 0.0204 0.0302
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0133 0.0554 0.0828
Onchocerca volvulus Peroxidasin homolog 0.0162 0.0686 0.1692
Plasmodium falciparum protein kinase 5 0.0021 0.005 0.0067
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0477 0.2107 0.315
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0036 0.0114 0.1011
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Schistosoma mansoni amine GPCR 0.0028 0.0078 0.0114
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.002 0.0045 0.0093
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0032 0.0229
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0037 0.0266
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0223 0.2013
Schistosoma mansoni topbp1 0.0012 0.0009 0.001
Loa Loa (eye worm) nuclear hormone receptor 0.0063 0.0237 0.0354
Onchocerca volvulus Neuropeptide F receptor homolog 0.0028 0.0078 0.0193
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0078 0.0078
Schistosoma mansoni tyrosine kinase 0.0026 0.0069 0.0101
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Onchocerca volvulus 0.0028 0.0078 0.0193
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0078 0.0117
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0013 0.0014 0.0079
Loa Loa (eye worm) hypothetical protein 0.0251 0.1086 0.1623
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0033 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Leishmania major phosphatidylinositol 3-kinase, putative 0.0012 0.0006 0.0007
Trypanosoma cruzi ribonuclease H1, putative 0.0014 0.0017 0.0108
Schistosoma mansoni hypothetical protein 0.0058 0.0216 0.032
Onchocerca volvulus 0.0028 0.0078 0.0193
Echinococcus granulosus expressed conserved protein 0.0132 0.0549 0.082
Schistosoma mansoni hypothetical protein 0.0055 0.0204 0.0302
Schistosoma mansoni neuropeptide receptor 0.0028 0.0078 0.0114
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0075 0.0293 0.2294
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.0033 0.0062
Loa Loa (eye worm) cysteine protease 0.0019 0.0037 0.0056
Chlamydia trachomatis DNA gyrase subunit B 0.0039 0.0129 0.24
Onchocerca volvulus 0.0028 0.0078 0.0193
Brugia malayi small heat shock protein 0.0624 0.2772 0.4144
Entamoeba histolytica hypothetical protein 0.0012 0.0009 0.0079
Echinococcus granulosus Ankyrin 0.0048 0.0169 0.0253
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0021 0.005 0.0075
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0012 0.0006 0.0009
Plasmodium vivax DNA topoisomerase II, putative 0.0027 0.0074 0.0103
Brugia malayi Pre-SET motif family protein 0.0018 0.0034 0.0051
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0131 0.121
Loa Loa (eye worm) phosphatidylinositol 3 0.0125 0.0516 0.0771
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0076 0.0571
Toxoplasma gondii hypothetical protein 0.0251 0.1086 0.1616
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0053 0.0388
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Echinococcus multilocularis G protein coupled receptor 139 0.0028 0.0078 0.0078
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0034 0.0105 0.0105
Brugia malayi cytochrome P450 0.002 0.0045 0.0068
Schistosoma mansoni rab6-interacting 0.0205 0.0878 0.131
Echinococcus granulosus neutral alpha glucosidase AB 0.0106 0.0431 0.0645
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0078 0.0117
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0022 0.0054 0.045
Schistosoma mansoni histamine h1 receptor 0.0028 0.0078 0.0114
Onchocerca volvulus 0.0019 0.0037 0.0092
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0027 0.0073 0.0676
Brugia malayi beta-lactamase family protein 0.0027 0.0075 0.0112
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0039 0.0131 0.1167
Loa Loa (eye worm) hypothetical protein 0.0049 0.0177 0.0264
Schistosoma mansoni neuropeptide receptor 0.0028 0.0078 0.0114
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0075 0.0104
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0078 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Entamoeba histolytica hypothetical protein, conserved 0.0251 0.1086 1
Echinococcus granulosus survival motor neuron protein 1 0.0484 0.2137 0.3195
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0066
Brugia malayi Variant SH3 domain containing protein 0.0016 0.0026 0.0039
Echinococcus multilocularis dro:myosuppressin receptor 0.0028 0.0078 0.0078
Brugia malayi Tachykinin-like peptides receptor 99D 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.0205 0.0878 0.1312
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0012 0.0006 0.0009
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0053 0.0442
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0018 0.0032 0.0041
Loa Loa (eye worm) hypothetical protein 0.019 0.081 0.121
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0012 0.0006 0.0001
Mycobacterium ulcerans putative regulatory protein 0.004 0.0134 0.0319
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0237 0.0354
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.002 0.0041 0.0059
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0033 0.0256
Echinococcus multilocularis TGF beta receptor type 1 0.0053 0.0191 0.0191
Onchocerca volvulus Dual oxidase homolog 0.0161 0.0681 0.1679
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0116 0.0477 0.12
Schistosoma mansoni protein kinase 0.0041 0.0138 0.0204
Brugia malayi nuclear receptor NHR-67 0.0063 0.0237 0.0354
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0133 0.0554 0.0828
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0009 0.0039
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0027 0.0075 0.0109
Leishmania major alpha glucosidase II subunit, putative 0.0106 0.0431 0.3944
Trichomonas vaginalis alpha-glucosidase, putative 0.0106 0.0431 0.3393
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0028 0.0195
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0049 0.0175 0.0175
Echinococcus multilocularis FTZ F1 alpha 0.0133 0.0554 0.0554
Onchocerca volvulus 0.0019 0.0037 0.0092
Leishmania major glycosyl hydrolase-like protein 0.0039 0.0131 0.1167
Brugia malayi MBOAT family protein 0.0251 0.1086 0.1623
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0078 0.0117
Brugia malayi RNA recognition motif domain containing protein 0.0136 0.0567 0.0848
Entamoeba histolytica cell division protein kinase 2, putative 0.0021 0.005 0.0462
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0054 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0053 0.0388
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0053 0.0442
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0045 0.0326
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0032 0.0229
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.002 0.0045 0.0093
Loa Loa (eye worm) animal heme peroxidase 0.0161 0.0681 0.1018
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0175 0.0742 0.6832
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0034 0.0048
Echinococcus granulosus allatostatin A receptor 0.0028 0.0078 0.0117
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0027 0.0074 0.0182
Echinococcus granulosus FTZ F1 alpha 0.0133 0.0554 0.0828
Brugia malayi MBOAT family protein 0.0251 0.1086 0.1623
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0059 0.0221 0.055
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.1492 0.669 1
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0431 0.3944
Plasmodium vivax DNA gyrase subunit B, putative 0.0059 0.0221 0.0323
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.002 0.0044 0.0066
Schistosoma mansoni sterol O-acyltransferase 1 0.0251 0.1086 0.162
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0083 0.0633
Echinococcus granulosus jun protein 0.0277 0.1205 0.1801
Plasmodium vivax SET domain protein, putative 0.0018 0.0034 0.0043
Leishmania major glycerol uptake protein, putative 0.0251 0.1086 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Schistosoma mansoni tyrosinase precursor 0.0091 0.0363 0.054
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.002 0.0045 0.0093
Brugia malayi Cathepsin L-like precursor 0.0012 0.0009 0.0014
Brugia malayi hypothetical protein 0.0012 0.0009 0.0013
Brugia malayi Protein kinase domain containing protein 0.0047 0.0167 0.025
Schistosoma mansoni nck2/grb4 0.0016 0.0026 0.0036
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0251 0.1086 0.1086
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0133 0.0554 0.0828
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0014
Trichomonas vaginalis set domain proteins, putative 0.0141 0.0592 0.4669
Brugia malayi Hint module family protein 0.0047 0.0164 0.0245
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0028 0.0078 0.0078
Trichomonas vaginalis alpha-glucosidase, putative 0.0106 0.0431 0.3393
Loa Loa (eye worm) hypothetical protein 0.0133 0.0554 0.0828
Schistosoma mansoni zinc finger protein 0.0063 0.0237 0.0351
Schistosoma mansoni tyrosine kinase 0.0026 0.0069 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0092 0.0703
Schistosoma mansoni alpha glucosidase 0.0106 0.0431 0.0642
Brugia malayi Pre-SET motif family protein 0.0124 0.0515 0.0769
Brugia malayi Calcitonin receptor-like protein seb-1 0.0175 0.0744 0.1113
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.032 0.1399 0.2091
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0063 0.0237 0.0354
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0078 0.0117
Schistosoma mansoni nuclear hormone receptor 0.0063 0.0237 0.0351
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0036 0.0114 0.1011
Echinococcus multilocularis somatostatin receptor 0.0028 0.0078 0.0078
Loa Loa (eye worm) MBOAT family protein 0.0251 0.1086 0.1623
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.0033 0.007
Trichomonas vaginalis porcupine, putative 0.0251 0.1086 0.8583
Schistosoma mansoni hypothetical protein 0.0251 0.1086 0.162
Brugia malayi Blistered cuticle protein 3 0.0161 0.0681 0.1018
Loa Loa (eye worm) hypothetical protein 0.0133 0.0554 0.0828
Schistosoma mansoni tyrosine kinase 0.0029 0.0085 0.0124
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0129 0.0535 0.1349
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Onchocerca volvulus 0.002 0.0044 0.0109
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0033 0.0256
Schistosoma mansoni DNA ligase IV 0.0012 0.0009 0.001
Brugia malayi Protein kinase domain containing protein 0.0019 0.0037 0.0056
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.0033 0.0062
Brugia malayi TAR-binding protein 0.0136 0.0567 0.0848
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0047 0.0167 0.025
Brugia malayi hypothetical protein 0.0083 0.033 0.0493
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0028 0.0078 0.0114
Echinococcus granulosus Desert hedgehog protein 0.0172 0.0729 0.1089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0078 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.0045 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0133 0.0554 0.0828
Echinococcus multilocularis tar DNA binding protein 0.0136 0.0567 0.0567
Brugia malayi RNA, U transporter 1 0.0085 0.0338 0.0506
Loa Loa (eye worm) hypothetical protein 0.0484 0.2137 0.3195
Echinococcus granulosus L aminoadipate semialdehyde 0.005 0.0178 0.0265
Brugia malayi tailless protein 0.0063 0.0237 0.0354
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0076 0.0571
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0053 0.0395
Schistosoma mansoni amine GPCR 0.0028 0.0078 0.0114
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.0045 0.0102
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0273 0.2479
Echinococcus multilocularis ribonuclease H1 0.0014 0.0017 0.0017
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0013 0.0014 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.0271 0.0404
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0037 0.0056
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0027 0.0074 0.0182
Toxoplasma gondii phosphofructokinase PFKII 0.0018 0.0032 0.0041
Brugia malayi jmjC domain containing protein 0.0035 0.0112 0.0167
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0023 0.0056 0.0076
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0011 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0014 0.0016 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0009 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0273 0.2479
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0053 0.0605
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0045 0.0325
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0033 0.0256
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.014 0.0583 0.0872
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0028 0.0078 0.0117
Echinococcus multilocularis tyrosine protein kinase shark 0.0011 0.0002 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0078 0.0114
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0023 0.0056 0.0081
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0028 0.0195
Loa Loa (eye worm) phosphatidylinositol 3 0.0013 0.0014 0.0021
Brugia malayi MBOAT family protein 0.0251 0.1086 0.1623
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0034 0.0034
Brugia malayi SRC-1 0.0034 0.0105 0.0157
Schistosoma mansoni neuropeptide f receptor 76f 0.0028 0.0078 0.0114
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0105 0.0105
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0011 0.0005 0.0008
Entamoeba histolytica cysteine protease, putative 0.0019 0.0037 0.0343
Loa Loa (eye worm) TK/INSR protein kinase 0.0019 0.0037 0.0056
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0047 0.0168 0.025
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.007 0.0271 0.0404
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0023 0.0056 0.0515
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0034 0.0105 0.0157
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0012 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Onchocerca volvulus 0.0019 0.0037 0.0092
Mycobacterium tuberculosis Conserved protein 0.0027 0.0075 0.0177
Schistosoma mansoni alpha-glucosidase 0.0411 0.1808 0.27
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0048 0.0169 0.0251
Trichomonas vaginalis replication factor C large subunit, putative 0.0012 0.0009 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0017 0.0029 0.0043
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0063 0.0472
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Echinococcus multilocularis tyrosine protein kinase HCK 0.0017 0.0032 0.0032
Trichomonas vaginalis alpha-glucosidase, putative 0.0106 0.0431 0.3393
Loa Loa (eye worm) latrophilin receptor protein 2 0.0055 0.0204 0.0304
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0251 0.1086 1
Trypanosoma cruzi cdc2-related kinase 3 0.0021 0.005 0.0416
Loa Loa (eye worm) FKBP5 protein 0.0023 0.0056 0.0084
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0024 0.0063 0.0063
Schistosoma mansoni tyrosine kinase 0.0232 0.0999 0.1491
Echinococcus multilocularis microtubule associated protein 2 0.1307 0.5857 0.5857
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0078 0.0114
Schistosoma mansoni aryl hydrocarbon receptor 0.0057 0.0209 0.031
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0023 0.0056 0.047
Echinococcus granulosus potassium voltage gated channel subfamily KQT 0.0044 0.0151 0.0226
Schistosoma mansoni biogenic amine receptor 0.0028 0.0078 0.0114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0273 0.2479
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0242 0.1048 0.1566
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.0045 0.0102
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0035 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.007 0.0271 0.0404
Loa Loa (eye worm) ctsf protein 0.0019 0.0037 0.0056
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0112
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0037 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0061 0.0457
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0034 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0133 0.0554 0.0825
Plasmodium falciparum importin beta, putative 0.003 0.0089 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Loa Loa (eye worm) diacylglycerol acyltransferase 0.1492 0.669 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0116 0.0477 0.1192
Trypanosoma brucei ribonuclease H1 0.0014 0.0017 0.0108
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0129 0.0535 0.1349
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0037 0.0056
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0091 0.0363 0.0542
Plasmodium vivax 6-phosphofructokinase, putative 0.0018 0.0032 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0114 0.0879
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0045 0.0326
Onchocerca volvulus 0.0012 0.0009 0.0021
Plasmodium vivax protein kinase Crk2 0.0021 0.005 0.0067
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.0045 0.0102
Brugia malayi nuclear receptor NHR-88 0.0063 0.0237 0.0354
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0131 0.1013
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0177 0.0264
Loa Loa (eye worm) CYP4Cod1 0.002 0.0045 0.0068
Onchocerca volvulus 0.0063 0.0237 0.0583
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0018 0.0034 0.0043
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0131 0.1013
Plasmodium vivax 6-phosphofructokinase, putative 0.0018 0.0032 0.0041
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0078 0.0117
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0027 0.0073 0.0676
Brugia malayi latrophilin 2 splice variant baaae 0.012 0.0494 0.0739
Brugia malayi glutathione reductase 0.0051 0.0183 0.0273
Loa Loa (eye worm) hypothetical protein 0.0164 0.0693 0.1035
Leishmania major trypanothione reductase 0.0051 0.0183 0.1644
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0133 0.0554 0.0825
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0078 0.0117
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.027 0.1171 0.175
Echinococcus multilocularis tumor protein p63 0.0243 0.1049 0.1049
Schistosoma mansoni tyrosine kinase 0.0029 0.0085 0.0124
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Onchocerca volvulus 0.0028 0.0078 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Entamoeba histolytica cell division protein kinase 2, putative 0.0021 0.005 0.0462
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.1492 0.669 1
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.002 0.0045 0.0093
Schistosoma mansoni hypothetical protein 0.0028 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) ShTK domain-containing protein 0.0091 0.0363 0.0542
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0021 0.005 0.0075
Schistosoma mansoni lipoxygenase 0.0729 0.3244 0.4848
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0014
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0251 0.1086 0.1086
Echinococcus multilocularis tyrosine protein kinase Blk 0.0024 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0012 0.0006 0.0009
Brugia malayi nuclear receptor RXR 0.007 0.0271 0.0404
Echinococcus granulosus 6 phosphofructokinase 0.0065 0.0246 0.0368
Brugia malayi beta-lactamase 0.0027 0.0075 0.0112
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0028 0.0078 0.0114
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0028 0.0078 0.0114
Mycobacterium leprae putative cytochrome p450 0.002 0.0045 0.0093
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0037 0.0092
Mycobacterium leprae conserved hypothetical protein 0.0014 0.0016 0.002
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0567 0.0846
Loa Loa (eye worm) isocitrate dehydrogenase 0.0011 0.0005 0.0008
Echinococcus granulosus tyrosine protein kinase shark 0.0011 0.0002 0.0003
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0033 0.0232
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0078 0.0114
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0033 0.0256
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0065 0.0246 0.0606
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0027 0.0073 0.0553
Mycobacterium tuberculosis Probable lipase LipE 0.0027 0.0075 0.0177
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0033 0.0232
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.002 0.0045 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0009 0.0046
Trypanosoma brucei ingi protein (ORF1) 0.0015 0.0022 0.0158
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.014 0.0583 0.087
Echinococcus granulosus lipoxygenase domain containing protein 0.0205 0.0878 0.1312
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0028 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Brugia malayi Animal haem peroxidase family protein 0.0162 0.0686 0.1025
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0033 0.0041
Brugia malayi protein-tyrosine kinase 0.0024 0.0063 0.0095
Schistosoma mansoni polycystin 1-related 0.0205 0.0878 0.131
Loa Loa (eye worm) cytochrome P450 family protein 0.0102 0.0416 0.0621
Schistosoma mansoni tyrosine kinase 0.0019 0.0037 0.0053
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0143 0.0597 0.089
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0037 0.0343
Echinococcus granulosus neuropeptide receptor A26 0.0028 0.0078 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0133 0.0554 0.0828
Echinococcus granulosus cyclin dependent kinase 1 0.0021 0.005 0.0075
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0014 0.0016 0.0017
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0033 0.0046
Schistosoma mansoni tyrosinase precursor 0.0091 0.0363 0.054
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0112 0.0165
Echinococcus multilocularis L aminoadipate semialdehyde 0.005 0.0178 0.0178
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0021 0.005 0.0075
Brugia malayi Probable DNA topoisomerase II 0.0027 0.0074 0.011
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0028 0.0078 0.0117
Leishmania major GTP-binding protein, putative 0.0022 0.0053 0.0442
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.0045 0.0371
Plasmodium vivax vivapain-2 0.0019 0.0037 0.0048
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0033 0.0041
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0174 0.026
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0037 0.0037
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1097 0.4908 0.4908
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0246 0.1926
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0078 0.0117
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0036 0.0114 0.1054
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0133 0.0554 0.0828
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Plasmodium falciparum diacylglycerol O-acyltransferase 0.1492 0.669 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0133 0.0554 0.0828
Brugia malayi Animal haem peroxidase family protein 0.0161 0.0681 0.1018
Echinococcus multilocularis Ankyrin 0.0048 0.0169 0.0169
Echinococcus granulosus thyroid hormone receptor alpha 0.0063 0.0237 0.0354
Echinococcus multilocularis NCK adaptor protein 0.0016 0.0026 0.0026
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0075 0.0293 0.2294
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0037 0.0037
Brugia malayi ecdysteroid receptor 0.0133 0.0554 0.0828
Schistosoma mansoni hypothetical protein 0.0028 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0112
Toxoplasma gondii 6-phosphofructokinase 0.0018 0.0032 0.0041
Brugia malayi G protein-coupled receptor F59B2.13 0.0028 0.0078 0.0117
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0063 0.0536
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0037 0.0296
Loa Loa (eye worm) hypothetical protein 0.0133 0.0554 0.0828
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0012 0.0006 0.0007
Schistosoma mansoni nuclear receptor 0.0063 0.0237 0.0351
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0075 0.0293 0.2294
Brugia malayi Dopamine receptor 0.0028 0.0078 0.0117
Mycobacterium ulcerans DNA gyrase subunit B 0.0059 0.0221 0.0542
Echinococcus granulosus Protein patched homolog 1 0.006 0.0225 0.0337
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0053 0.0079
Echinococcus granulosus somatostatin receptor 0.0028 0.0078 0.0117
Loa Loa (eye worm) MBOAT family protein 0.0251 0.1086 0.1623
Schistosoma mansoni immunophilin 0.002 0.0042 0.006
Trichomonas vaginalis esterase, putative 0.0027 0.0075 0.0565
Loa Loa (eye worm) fibroinase 0.0019 0.0037 0.0056
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0028 0.0078 0.0117
Onchocerca volvulus 0.0028 0.0078 0.0193
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0742 0.5855
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0882 0.3937 1
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0052 0.019 0.1475
Onchocerca volvulus 0.0028 0.0078 0.0193
Brugia malayi Melatonin receptor type 1A 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.012 0.0494 0.0739
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0014 0.0016 0.0028
Schistosoma mansoni neuropeptide receptor 0.0028 0.0078 0.0114
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0237 0.0237
Loa Loa (eye worm) TK protein kinase 0.0017 0.0032 0.0048
Trichomonas vaginalis sucrase-isomaltase, putative 0.0106 0.0431 0.3393
Onchocerca volvulus 0.0028 0.0078 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Brugia malayi nuclear hormone receptor family member nhr-6 0.0063 0.0237 0.0354
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0116 0.0477 0.12
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0223 0.0333
Loa Loa (eye worm) hypothetical protein 0.0063 0.0237 0.0354
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0112
Loa Loa (eye worm) hypothetical protein 0.0017 0.0028 0.0042
Echinococcus granulosus tyrosine protein kinase HCK 0.0017 0.0032 0.0048
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0062
Trypanosoma cruzi Aph-1 protein, putative 0.0115 0.0474 0.4338
Onchocerca volvulus 0.0019 0.0037 0.0092
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0071 0.0273 0.2518
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0172 0.0731 0.0731
Entamoeba histolytica hypothetical protein 0.0014 0.0016 0.0151
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0037 0.0037
Leishmania major mitochondrial DNA topoisomerase II 0.0047 0.0166 0.149
Echinococcus granulosus geminin 0.0188 0.08 0.1197
Schistosoma mansoni protein kinase 0.0041 0.0138 0.0204
Onchocerca volvulus 0.0028 0.0078 0.0193
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0037 0.0296
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0078 0.0114
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.0045 0.0102
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0012 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0056 0.047
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0012 0.0009 0.0013
Schistosoma mansoni importin beta-1 0.003 0.0089 0.013
Echinococcus multilocularis neuropeptide receptor A26 0.0028 0.0078 0.0078
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0044 0.0151 0.0226
Entamoeba histolytica phosphofructokinase, putative 0.0065 0.0246 0.227
Echinococcus multilocularis hedgehog 0.0172 0.0729 0.0729
Schistosoma mansoni coup transcription factor 0.0133 0.0554 0.0825
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0063 0.0237 0.0583
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0037 0.0048
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0022 0.0055 0.0458
Trypanosoma cruzi ribonuclease H1, putative 0.0014 0.0017 0.0108
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.002 0.0045 0.0093
Echinococcus granulosus tyrosine protein kinase Lyn 0.0035 0.0111 0.0166
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0012 0.0006 0.0006
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0027 0.0073 0.0107
Trypanosoma cruzi cdc2-related kinase 1 0.0021 0.005 0.0416
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0078 0.0078
Onchocerca volvulus 0.0161 0.0681 0.1679
Leishmania major importin beta-1 subunit, putative 0.0024 0.0063 0.0536
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0133 0.0554 0.0825
Leishmania major cytochrome p450-like protein 0.002 0.0045 0.0371
Brugia malayi Nuclear hormone receptor-like 1 0.0133 0.0554 0.0828
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0045 0.0371
Trypanosoma brucei RNA helicase, putative 0.0053 0.0192 0.1727
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0273 0.2479
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0129 0.0535 0.1341
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0027 0.0074 0.011
Schistosoma mansoni topbp1 0.0012 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.0045 0.0102
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.0587 0.0587
Echinococcus granulosus neuropeptide s receptor 0.0028 0.0078 0.0117
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0131 0.1013
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0027 0.0074 0.0074
Trypanosoma brucei glycosyl hydrolase-like protein 0.0039 0.0131 0.1167
Schistosoma mansoni cytochrome P450 0.002 0.0045 0.0065
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0023 0.0056 0.0121
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0028 0.0078 0.0117
Schistosoma mansoni opsin-like receptor 0.0028 0.0078 0.0114
Onchocerca volvulus Chorion peroxidase homolog 0.0161 0.0681 0.1679
Trypanosoma cruzi Aph-1 protein, putative 0.0115 0.0474 0.4338
Plasmodium vivax replication factor C subunit 1, putative 0.0012 0.0009 0.0005
Echinococcus granulosus intermediate filament protein 0.002 0.0044 0.0066
Loa Loa (eye worm) hypothetical protein 0.0091 0.0363 0.0542
Trypanosoma cruzi glycerol uptake protein, putative 0.0251 0.1086 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0045 0.0093
Echinococcus multilocularis c src tyrosine kinase 0.002 0.0041 0.0041
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0175 0.0744 0.1113
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0117
Loa Loa (eye worm) hypothetical protein 0.0161 0.0681 0.1018
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.0045 0.0102
Echinococcus multilocularis ecdysone induced protein 78C 0.0133 0.0554 0.0554
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0027 0.0073 0.0631
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0013
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0023 0.0056 0.0084
Brugia malayi Cathepsin L-like precursor 0.0019 0.0037 0.0056
Brugia malayi Intermediate filament tail domain containing protein 0.002 0.0044 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0114 0.0879
Schistosoma mansoni hypothetical protein 0.0058 0.0216 0.032
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0053 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0037 0.0266
Echinococcus multilocularis g-protein coupled receptor 0.0028 0.0078 0.0078
Brugia malayi hypothetical protein 0.0028 0.0078 0.0117
Echinococcus granulosus growth factor receptor bound protein 2 0.0016 0.0026 0.0039
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0056 0.047
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0014 0.0016 0.0017

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 5 nM Inhibitory concentration against Gamma-secretase in whole cell inhibition assay using SH-SY5Y cells ChEMBL. 15603957
IC50 (functional) = 5 nM Inhibitory concentration against Gamma-secretase in whole cell inhibition assay using SH-SY5Y cells ChEMBL. 15603957

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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