Detailed information for compound 337925

Basic information

Technical information
  • TDR Targets ID: 337925
  • Name: 4-[(1-phenylsulfanylnaphthalen-2-yl)methyl]-5 -piperidin-4-yl-1,2-oxazol-3-one
  • MW: 416.535 | Formula: C25H24N2O2S
  • H donors: 2 H acceptors: 2 LogP: 5.73 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1noc(c1Cc1ccc2c(c1Sc1ccccc1)cccc2)C1CCNCC1
  • InChi: 1S/C25H24N2O2S/c28-25-22(23(29-27-25)18-12-14-26-15-13-18)16-19-11-10-17-6-4-5-9-21(17)24(19)30-20-7-2-1-3-8-20/h1-11,18,26H,12-16H2,(H,27,28)
  • InChiKey: UCIQWRVUTVCZBG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[(1-phenylsulfanyl-2-naphthyl)methyl]-5-(4-piperidyl)isoxazol-3-one
  • 4-[[1-(phenylthio)-2-naphthyl]methyl]-5-(4-piperidinyl)-3-isoxazolone
  • 4-[[1-(phenylthio)-2-naphthyl]methyl]-5-(4-piperidyl)-4-isoxazolin-3-one
  • 4-[[1-(phenylthio)-2-naphthyl]methyl]-5-(4-piperidyl)isoxazol-3-one

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus GABA-A receptor; anion channel Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 461 aa 27.8 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 454 aa 30.4 %
Echinococcus granulosus glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Echinococcus multilocularis glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Echinococcus multilocularis glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 478 aa 28.7 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 446 aa 29.1 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 468 aa 28.6 %
Brugia malayi Cation transporter family protein GABA-A receptor; anion channel   467 aa 453 aa 28.5 %
Echinococcus granulosus glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 439 aa 29.6 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 434 aa 26.7 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 446 aa 28.0 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 454 aa 29.5 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 447 aa 25.7 %
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative GABA-A receptor; anion channel   467 aa 384 aa 19.5 %
Onchocerca volvulus Eukaryotic initiation factor 4A-III homolog GABA-A receptor; anion channel   467 aa 453 aa 26.9 %
Onchocerca volvulus Gamma-aminobutyric acid receptor subunit beta homolog GABA-A receptor; anion channel   467 aa 433 aa 34.6 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 435 aa 29.7 %
Onchocerca volvulus Large subunit GTPase 1 homolog GABA-A receptor; anion channel   467 aa 496 aa 26.0 %
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit GABA-A receptor; anion channel   467 aa 379 aa 19.3 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 441 aa 33.8 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog GABA-A receptor; anion channel   467 aa 418 aa 19.6 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 494 aa 25.5 %
Schistosoma mansoni Cys-loop ligand gated ion channel subunit GABA-A receptor; anion channel   467 aa 479 aa 29.2 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 375 aa 21.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Cell division protein FtsZ 0.0396 0.1605 0.418
Mycobacterium ulcerans hypothetical protein 0.0145 0.055 0.3383
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.011 0.0403 0.0616
Loa Loa (eye worm) nuclear hormone receptor 0.0052 0.0159 0.0242
Echinococcus multilocularis tubulin alpha chain 0.1171 0.4862 0.486
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0012
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0111 0.0408 0.062
Echinococcus granulosus beta tubulin 0.1563 0.6509 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0392 0.1002
Schistosoma mansoni ferritin 0.0018 0.0016 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0396 0.1605 0.2461
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0021 0.0029 0.0041
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.0468 0.0712
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0011 0.0007
Brugia malayi nuclear receptor NHR-88 0.011 0.0403 0.0616
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Trichomonas vaginalis tubulin beta chain, putative 0.1171 0.4862 0.7468
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0396 0.1605 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0036 0.0053
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0139 0.021
Schistosoma mansoni tyrosine kinase 0.0252 0.1002 0.1537
Trichomonas vaginalis ferritin, putative 0.0018 0.0016 0.0018
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.005 0.0075
Schistosoma mansoni tyrosine kinase 0.0252 0.1002 0.1537
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.005 0.0074
Leishmania major beta tubulin 0.1563 0.6509 1
Toxoplasma gondii tubulin, putative 0.0052 0.0162 0.0245
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0695 0.2863 0.4394
Echinococcus granulosus Tubulin alpha 1 chain 0.1171 0.4862 0.7468
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Brugia malayi Patched related family protein 10 0.0037 0.0096 0.0146
Onchocerca volvulus 0.0145 0.055 0.2773
Trypanosoma cruzi beta tubulin, putative 0.1563 0.6509 1
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0072 0.0104
Echinococcus granulosus expressed protein 0.0018 0.0016 0.0018
Echinococcus multilocularis beta tubulin 0.1563 0.6509 0.6508
Loa Loa (eye worm) hypothetical protein 0.0055 0.0174 0.0265
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0129 0.0198
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0052 0.0159 0.0155
Schistosoma mansoni tubulin subunit beta 0.1563 0.6509 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0036 0.0053
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0036
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0217 0.0331
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0049 0.0146 0.0142
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.055 0.0841
Echinococcus multilocularis 0.0143 0.0543 0.0539
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0011 0.0015
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0055 0.0174 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Plasmodium vivax vivapain-2 0.0017 0.0011 0.0017
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0241 0.0367
Echinococcus multilocularis ferritin 0.0018 0.0016 0.0012
Trichomonas vaginalis tubulin alpha chain, putative 0.1563 0.6509 1
Schistosoma mansoni hypothetical protein 0.0066 0.022 0.0335
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0143 0.0217
Echinococcus multilocularis epidermal growth factor receptor 0.0467 0.1903 0.1899
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Schistosoma mansoni Smad4 0.0024 0.0043 0.0062
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0443 0.1133
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0111 0.0408 0.0626
Schistosoma mansoni integrin alpha-ps 0.0068 0.0228 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0036
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Brugia malayi hypothetical protein 0.0047 0.014 0.0213
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0024 0.004 0.0059
Loa Loa (eye worm) patched family protein 0.0037 0.0096 0.0146
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.001 0.0015
Onchocerca volvulus 0.0049 0.0148 0.0705
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0096 0.0141
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0011 0.0015
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0023 0.0036 0.0053
Echinococcus multilocularis tubulin alpha chain 0.1171 0.4862 0.486
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0011 0.0002
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0115 0.0425 0.065
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Toxoplasma gondii beta-1 tubulin, putative 0.1563 0.6509 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0181 0.1074
Toxoplasma gondii cathepsin CPL 0.0017 0.0011 0.0014
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.01 0.0152
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0476 0.1941 0.2977
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.055 0.0841
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0011 0.0004
Echinococcus granulosus tubulin alpha 0.0872 0.3605 0.5535
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0091 0.0133
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.002 0.0024 0.0034
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.011 0.0403 0.0613
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0023 0.0036 0.0053
Brugia malayi PAS domain containing protein 0.0048 0.0145 0.022
Brugia malayi Nuclear hormone receptor family member nhr-25 0.011 0.0403 0.0616
Loa Loa (eye worm) patched family protein 0.0037 0.0096 0.0146
Entamoeba histolytica cysteine protease, putative 0.0017 0.0011 0.0017
Plasmodium vivax tubulin alpha chain, putative 0.1171 0.4862 0.7469
Loa Loa (eye worm) hypothetical protein 0.0162 0.0624 0.0956
Echinococcus multilocularis tubulin alpha 0.0872 0.3605 0.3602
Echinococcus multilocularis Tubulin beta 2C chain 0.1563 0.6509 0.6508
Plasmodium vivax hypothetical protein, conserved 0.0145 0.055 0.0844
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.055 0.0838
Trichomonas vaginalis tubulin beta chain, putative 0.1171 0.4862 0.7468
Echinococcus granulosus tubulin beta 1 chain 0.1563 0.6509 1
Schistosoma mansoni tyrosine kinase 0.0246 0.0975 0.1496
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0011 0.0002
Trypanosoma brucei beta tubulin 0.0872 0.3605 0.5535
Loa Loa (eye worm) integrin alpha pat-2 0.0234 0.0927 0.1421
Brugia malayi hypothetical protein 0.0037 0.0096 0.0146
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.011 0.0403 0.0613
Mycobacterium tuberculosis Conserved protein 0.0145 0.055 0.1414
Brugia malayi Tubulin alpha-2 chain 0.1171 0.4862 0.7469
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.011 0.0403 0.0613
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0448 0.1826 0.2803
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0011 0.0004
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0096 0.0144
Schistosoma mansoni tyrosine kinase 0.002 0.0024 0.0034
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Echinococcus multilocularis follistatin 0.0038 0.01 0.0096
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0036 0.0052
Schistosoma mansoni lamin 0.0027 0.0054 0.008
Schistosoma mansoni smad1 5 8 and 0.0024 0.0043 0.0062
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0208 0.0316
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0174 0.0265
Schistosoma mansoni hypothetical protein 0.016 0.0616 0.0943
Loa Loa (eye worm) hypothetical protein 0.0084 0.0294 0.0449
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0036 0.0032
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Loa Loa (eye worm) hypothetical protein 0.0047 0.014 0.0213
Loa Loa (eye worm) tubulin alpha 2 0.0775 0.3198 0.4912
Echinococcus granulosus agrin 0.0038 0.01 0.0148
Brugia malayi beta-lactamase family protein 0.0145 0.055 0.0842
Echinococcus multilocularis FTZ F1 alpha 0.011 0.0403 0.0399
Loa Loa (eye worm) hypothetical protein 0.0055 0.0174 0.0265
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0181 0.0177
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0645 0.0985
Leishmania major hypothetical protein, conserved 0.0145 0.055 0.0838
Brugia malayi hypoxia-induced factor 1 0.015 0.0571 0.0874
Echinococcus multilocularis protein patched 0.0261 0.1039 0.1035
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0145 0.055 0.1414
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.001 0.0012
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0139 0.0214
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0059 0.0084
Brugia malayi Cathepsin L-like precursor 0.0017 0.0011 0.0015
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0058 0.0185 0.0281
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0072 0.0107
Brugia malayi Protein kinase domain containing protein 0.0152 0.0579 0.0887
Loa Loa (eye worm) fibroinase 0.0017 0.0011 0.0015
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0036 0.0049
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0011 0.0014
Giardia lamblia Gamma tubulin 0.0925 0.3829 0.5876
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.009 0.0132
Leishmania major beta tubulin 0.1563 0.6509 1
Echinococcus granulosus lamin 0.0027 0.0054 0.0076
Plasmodium falciparum alpha tubulin 2 0.1171 0.4862 0.7465
Brugia malayi nuclear hormone receptor family member nhr-6 0.0052 0.0159 0.0242
Brugia malayi nuclear receptor NHR-88 0.0052 0.0159 0.0242
Loa Loa (eye worm) hypothetical protein 0.0024 0.004 0.0059
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0023 0.0036 0.0049
Onchocerca volvulus Protein patched homolog 0.0037 0.0096 0.0439
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Echinococcus granulosus Tubulin alpha 1 chain 0.1171 0.4862 0.7468
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0096 0.0144
Schistosoma mansoni lamin 0.0027 0.0054 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0036
Toxoplasma gondii patched family protein 0.0037 0.0096 0.0145
Trichomonas vaginalis tubulin beta chain, putative 0.1563 0.6509 1
Trypanosoma brucei alpha tubulin 0.1171 0.4862 0.7468
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0036 0.0032
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0011 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1014 0.1552
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Brugia malayi AMP-binding enzyme family protein 0.0024 0.004 0.0059
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0775 0.3198 0.4909
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0104 0.0144
Echinococcus granulosus beta LACTamase domain containing family member 0.0145 0.055 0.0838
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0036 0.0053
Echinococcus multilocularis expressed protein 0.0038 0.01 0.0096
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0072 0.0246 0.1478
Onchocerca volvulus 0.0037 0.0096 0.0439
Echinococcus granulosus integrin alpha ps 0.0033 0.0079 0.0114
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.001 0.0008
Echinococcus granulosus nAChR subunit 0.0023 0.0036 0.0049
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.011 0.0403 0.0616
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0011 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.055 0.0841
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0028 0.0036
Loa Loa (eye worm) alpha-tubulin 0.1171 0.4862 0.7469
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0036
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0111 0.0408 0.062
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0155 0.0591 0.0587
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0061 0.009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Plasmodium vivax glutathione reductase, putative 0.0047 0.0139 0.0214
Loa Loa (eye worm) tubulin gamma chain 0.0925 0.3829 0.5881
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0015 0.0015
Entamoeba histolytica protein kinase, putative 0.0035 0.009 0.0138
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0185 0.0281
Mycobacterium ulcerans bacterioferritin BfrA 0.0018 0.0016 0.004
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0118 0.0178
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0049 0.0146 0.0142
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0148 0.0224
Schistosoma mansoni hypothetical protein 0.1378 0.5735 0.8811
Brugia malayi CXXC zinc finger family protein 0.0091 0.0322 0.0492
Trypanosoma brucei alpha tubulin 0.1171 0.4862 0.7468
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0036 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.004 0.0152
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0118 0.0178
Schistosoma mansoni tyrosine kinase 0.0049 0.0146 0.0221
Echinococcus granulosus insulin receptor 0.0152 0.0579 0.0883
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0042
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0129 0.0192
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0092 0.0134
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Onchocerca volvulus 0.0037 0.0096 0.0439
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.01 0.0151
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0044 0.0063
Brugia malayi prostaglandin transporter 0.0055 0.0174 0.0265
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.004 0.008
Echinococcus granulosus eukaryotic initiation factor 4A 0.0024 0.0044 0.006
Mycobacterium tuberculosis Probable lipase LipE 0.0145 0.055 0.1414
Echinococcus granulosus Niemann Pick C1 protein 0.087 0.3598 0.5524
Schistosoma mansoni glutaminase 0.029 0.116 0.1779
Plasmodium falciparum tubulin epsilon chain, putative 0.0924 0.3825 0.587
Leishmania major cathepsin L-like protease 0.0017 0.0011 0.0011
Plasmodium vivax RNA helicase-1, putative 0.0024 0.0044 0.0067
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0023 0.0036 0.0053
Brugia malayi Cytochrome P450 family protein 0.0026 0.005 0.0075
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0111 0.0408 0.0403
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Echinococcus multilocularis integrin beta 2 0.0231 0.0911 0.0907
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0054 0.0076
Schistosoma mansoni hypothetical protein 0.0033 0.0079 0.0117
Brugia malayi MH2 domain containing protein 0.0354 0.1428 0.2192
Trypanosoma brucei tubulin delta chain 0.0725 0.2988 0.4586
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0011 0.0011
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Schistosoma mansoni organic anion transporter 0.0055 0.0174 0.0264
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0092 0.0138
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trichomonas vaginalis tubulin gamma chain, putative 0.1563 0.6509 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0072 0.0246 0.0371
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0015 0.0035
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Echinococcus multilocularis Niemann Pick C1 protein 0.087 0.3598 0.3595
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0096 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0081 0.0118
Onchocerca volvulus 0.0257 0.1024 0.5215
Plasmodium vivax tubulin beta chain, putative 0.1563 0.6509 1
Toxoplasma gondii hypothetical protein 0.0037 0.0096 0.0145
Echinococcus multilocularis tubulin gamma 1 chain 0.0925 0.3829 0.3826
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0129 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0081 0.0118
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0443 0.2682
Loa Loa (eye worm) TK/EGFR protein kinase 0.0467 0.1903 0.2921
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0043 0.0038
Schistosoma mansoni apoferritin-2 0.0018 0.0016 0.0021
Leishmania major cathepsin L-like protease 0.0063 0.0208 0.0313
Echinococcus granulosus nuclear receptor 2DBD gamma 0.011 0.0403 0.0613
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0081 0.0118
Trichomonas vaginalis tubulin, putative 0.0476 0.1941 0.2977
Brugia malayi alpha-tubulin 0.1171 0.4862 0.7469
Leishmania major cytochrome p450-like protein 0.0026 0.005 0.0071
Loa Loa (eye worm) hypothetical protein 0.0177 0.0685 0.105
Schistosoma mansoni nuclear receptor 0.0052 0.0159 0.0241
Brugia malayi Niemann-Pick C1 protein precursor 0.0609 0.25 0.3839
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0096 0.0141
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0049 0.0146 0.0142
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0023 0.0036 0.0053
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0218 0.0859 0.0855
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0104 0.038 0.0376
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0393 0.0601
Loa Loa (eye worm) patched family protein 0.0037 0.0096 0.0146
Brugia malayi latrophilin 2 splice variant baaae 0.0143 0.0544 0.0833
Onchocerca volvulus 0.0037 0.0096 0.0439
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.0543 0.0831
Toxoplasma gondii alpha-tubulin I, putative 0.1171 0.4862 0.7468
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.001 0.0012
Onchocerca volvulus 0.0038 0.01 0.0459
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0028 0.0036
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0043 0.0063
Loa Loa (eye worm) hypothetical protein 0.0257 0.1024 0.157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Trichomonas vaginalis esterase, putative 0.0145 0.055 0.0838
Plasmodium vivax tubulin epsilon chain, putative 0.0924 0.3825 0.5877
Loa Loa (eye worm) hypothetical protein 0.0775 0.3198 0.4912
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Loa Loa (eye worm) nuclear receptor NHR-67 0.0052 0.0159 0.0242
Echinococcus multilocularis Smad4 0.0024 0.0043 0.0038
Plasmodium falciparum alpha tubulin 1 0.1171 0.4862 0.7465
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0392 0.1002
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0217 0.0331
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0028 0.0036
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trypanosoma cruzi zeta tubulin, putative 0.0946 0.3916 0.6015
Trichomonas vaginalis tubulin epsilon chain, putative 0.1171 0.4862 0.7468
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0072 0.011
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0043 0.0038
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0096 0.0092
Brugia malayi Integrin beta pat-3 precursor 0.0311 0.1251 0.1919
Loa Loa (eye worm) tubulin beta-2A chain 0.1563 0.6509 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0392 0.1002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.011 0.0403 0.0616
Brugia malayi Tubulin beta chain 0.0476 0.1941 0.298
Leishmania major beta tubulin 0.1563 0.6509 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.011 0.0403 0.0615
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0011 0.0015
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0023 0.0036 0.0032
Echinococcus granulosus epidermal growth factor receptor 0.0467 0.1903 0.2918
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0159 0.0241
Brugia malayi Patched protein homolog 1 0.0037 0.0096 0.0146
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0061 0.0091
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0072 0.0246 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0096 0.0141
Schistosoma mansoni tubulin subunit gamma 0.0925 0.3829 0.588
Brugia malayi Latrophilin receptor protein 2 0.0066 0.022 0.0336
Trichomonas vaginalis glutaminase, putative 0.029 0.116 0.1777
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0021 0.0029 0.0041
Schistosoma mansoni tubulin subunit beta 0.1563 0.6509 1
Treponema pallidum bacterioferrin (TpF1) 0.0018 0.0016 0.0087
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0145 0.055 0.0842
Schistosoma mansoni Tr4/Tr2 (homologue) 0.011 0.0403 0.0615
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0145 0.055 0.3383
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.004 0.0192
Leishmania major beta tubulin 0.1563 0.6509 1
Entamoeba histolytica tubulin family protein 0.1563 0.6509 1
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0044 0.006
Loa Loa (eye worm) BEN-1 protein 0.1563 0.6509 1
Leishmania major gamma-tubulin 0.0925 0.3829 0.5879
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Trypanosoma brucei alpha tubulin 0.1171 0.4862 0.7468
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0072 0.0104
Loa Loa (eye worm) tubulin alpha 2 0.0775 0.3198 0.4912
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0129 0.0192
Loa Loa (eye worm) hypothetical protein 0.0038 0.01 0.0152
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0036 0.0053
Echinococcus multilocularis peroxisome assembly protein 26 0.1171 0.4862 0.486
Loa Loa (eye worm) tubulin beta-1 chain 0.1563 0.6509 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.011 0.0403 0.0615
Onchocerca volvulus 0.0023 0.0036 0.0128
Leishmania major delta tubulin, putative 0.0725 0.2988 0.4586
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0023 0.0036 0.0053
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0036 0.0052
Schistosoma mansoni vesicular amine transporter 0.0021 0.0029 0.0041
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0113 0.0168
Echinococcus multilocularis epidermal growth factor receptor 0.0252 0.1002 0.0999
Schistosoma mansoni hypothetical protein 0.0066 0.022 0.0335
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.005 0.0075
Echinococcus multilocularis Tubulin beta 2C chain 0.1563 0.6509 0.6508
Trypanosoma brucei alpha tubulin, putative 0.0476 0.1941 0.2977
Echinococcus multilocularis sterol regulatory element binding protein 0.0261 0.1039 0.1035
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0036 0.0053
Echinococcus multilocularis Immunoglobulin 0.0021 0.0029 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-49 0.011 0.0403 0.0616
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.001 0.0008
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1171 0.4862 0.7468
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0058 0.0185 0.0181
Echinococcus granulosus Smad4 0.0024 0.0043 0.0059
Brugia malayi nuclear hormone receptor 0.0052 0.0159 0.0242
Echinococcus granulosus tyrosine protein kinase Btk29A 0.002 0.0024 0.0031
Brugia malayi hypothetical protein 0.0071 0.0241 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0059
Brugia malayi nuclear receptor RXR 0.0052 0.0159 0.0242
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.011 0.0403 0.0613
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0054 0.0076
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0023 0.0036 0.0052
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.022 0.0336
Loa Loa (eye worm) hypothetical protein 0.0033 0.0079 0.0118
Trypanosoma brucei alpha tubulin 0.1171 0.4862 0.7468
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0185 0.0282
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0111 0.0408 0.0403
Brugia malayi nuclear hormone receptor 0.011 0.0403 0.0616
Echinococcus multilocularis glycine receptor subunit beta 0.0023 0.0036 0.0032
Onchocerca volvulus 0.0091 0.0322 0.1601
Toxoplasma gondii transporter, major facilitator family protein 0.0055 0.0174 0.0264
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0079 0.0275 0.0271
Trypanosoma brucei zeta tubulin 0.0946 0.3916 0.6014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Echinococcus granulosus Tubulin beta 2C chain 0.1563 0.6509 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.011 0.0403 0.0616
Loa Loa (eye worm) steroid hormone receptor 0.011 0.0403 0.0616
Brugia malayi hypothetical protein 0.0235 0.093 0.1426
Schistosoma mansoni ferritin 0.0018 0.0016 0.0021
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0052 0.0159 0.0238
Toxoplasma gondii isocitrate dehydrogenase 0.0111 0.0408 0.0623
Trypanosoma cruzi epsilon tubulin, putative 0.0924 0.3825 0.5875
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0159 0.0238
Echinococcus multilocularis tubulin alpha 3 chain 0.1171 0.4862 0.486
Leishmania major cathepsin L-like protease 0.0063 0.0208 0.0313
Echinococcus granulosus tubulin alpha 1C chain 0.1171 0.4862 0.7468
Trypanosoma brucei beta tubulin 0.1563 0.6509 1
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0145 0.0219
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0049 0.0146 0.0142
Echinococcus granulosus nuclear receptor nhr 48 0.0052 0.0159 0.0238
Brugia malayi SRC-1 0.0049 0.0146 0.0222
Plasmodium falciparum thioredoxin reductase 0.0047 0.0139 0.0199
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.055 0.0838
Loa Loa (eye worm) hypothetical protein 0.0055 0.0174 0.0265
Echinococcus granulosus smad 0.0024 0.0043 0.0059
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0257 0.1024 0.157
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0096 0.0092
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.004 0.0192
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0018 0.0016 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0059
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0049 0.0146 0.0218
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Toxoplasma gondii alpha tubulin TUBA1 0.1171 0.4862 0.7468
Loa Loa (eye worm) TK/INSR protein kinase 0.0152 0.0579 0.0887
Loa Loa (eye worm) TK protein kinase 0.0042 0.0118 0.0179
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.001 0.0008
Echinococcus granulosus tyrosine protein kinase Src42A 0.0049 0.0146 0.0218
Leishmania major cathepsin L-like protease 0.0063 0.0208 0.0313
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.0543 0.0832
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.022 0.0336
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Loa Loa (eye worm) alpha-tubulin 0.1171 0.4862 0.7469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0081 0.0118
Echinococcus multilocularis tubulin epsilon chain 0.0924 0.3825 0.3823
Brugia malayi hypothetical protein 0.0478 0.1952 0.2997
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0241 0.0237
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0068 0.0103
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0011 0.0011
Plasmodium falciparum lipid/sterol:H+ symporter 0.0037 0.0096 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0028 0.0036
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0052 0.0159 0.0241
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.011 0.0403 0.0616
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0111 0.0408 0.0623
Trichomonas vaginalis tubulin, putative 0.0476 0.1941 0.2977
Plasmodium vivax tubulin gamma chain, putative 0.0925 0.3829 0.5882
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0118 0.0175
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0058 0.0185 0.0282
Schistosoma mansoni integrin beta subunit 0.0183 0.0712 0.1091
Toxoplasma gondii thioredoxin reductase 0.0047 0.0139 0.021
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0023 0.0036 0.0053
Echinococcus multilocularis ecdysone induced protein 78C 0.011 0.0403 0.0399
Leishmania major beta tubulin 0.1563 0.6509 1
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0246 0.0371
Schistosoma mansoni apoferritin-2 0.0018 0.0016 0.0021
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0392 0.1002
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0872 0.3605 0.5536
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0217 0.0327
Schistosoma mansoni cpg binding protein 0.0091 0.0322 0.0491
Echinococcus granulosus defective proboscis extension response 0.0021 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Brugia malayi MH2 domain containing protein 0.0024 0.0043 0.0063
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0011 0.0014
Brugia malayi tailless protein 0.0052 0.0159 0.0242
Trypanosoma cruzi alpha tubulin, putative 0.1171 0.4862 0.7468
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0645 0.0985
Loa Loa (eye worm) TK protein kinase 0.0107 0.0393 0.0601
Onchocerca volvulus 0.0145 0.055 0.2773
Loa Loa (eye worm) hypothetical protein 0.0145 0.055 0.0842
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0111 0.0408 0.0623
Brugia malayi protein-tyrosine kinase 0.0042 0.0118 0.0179
Schistosoma mansoni zinc finger protein 0.0052 0.0159 0.0241
Echinococcus granulosus ferritin 0.0018 0.0016 0.0018
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.021 0.0823 0.1262
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1014 0.1552
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0181 0.0449
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0129 0.0192
Toxoplasma gondii isocitrate dehydrogenase 0.0111 0.0408 0.0623
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.011 0.0403 0.0616
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0332 0.0328
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.093 0.0926
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0012
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0332 0.0508
Mycobacterium leprae cell division protein FtsZ 0.0396 0.1605 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0036 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1014 0.1552
Giardia lamblia Delta tubulin 0.0396 0.1605 0.2455
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0208 0.0316
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0096 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0091 0.0133
Echinococcus granulosus intermediate filament protein 0.0027 0.0054 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0645 0.0985
Brugia malayi Tyrosine-protein kinase abl-1 0.0127 0.0474 0.0726
Toxoplasma gondii patched family protein 0.0037 0.0096 0.0145
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0118 0.0175
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0129 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0036
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.001 0.0008
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.004 0.0192
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0174 0.0265
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0096 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.011 0.0403 0.0616
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0024 0.0044 0.0039
Entamoeba histolytica hypothetical protein 0.0072 0.0246 0.0377
Brugia malayi eukaryotic initiation factor 4A 0.0024 0.0044 0.0064
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0159 0.0761
Echinococcus multilocularis tubulin alpha chain 0.1171 0.4862 0.486
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0113 0.0109
Brugia malayi Cathepsin L-like precursor 0.0017 0.0011 0.0015
Echinococcus granulosus glycine receptor subunit beta 0.0023 0.0036 0.0049
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0118 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-19 0.011 0.0403 0.0616
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.011 0.0403 0.0615
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0091 0.0136
Mycobacterium tuberculosis Conserved protein 0.0145 0.055 0.1414
Loa Loa (eye worm) hypothetical protein 0.0038 0.01 0.0152
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.018 0.027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.006
Loa Loa (eye worm) ACC-1 protein 0.0023 0.0036 0.0053
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0129 0.0192
Brugia malayi hypothetical protein 0.0225 0.0886 0.1359
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0683 0.1043
Toxoplasma gondii ABC1 family protein 0.0145 0.055 0.0841
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Schistosoma mansoni nAChR subunit 0.0023 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0049 0.0148 0.0225
Echinococcus granulosus tubulin alpha chain 0.1171 0.4862 0.7468
Schistosoma mansoni tyrosine kinase 0.0467 0.1903 0.292
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Onchocerca volvulus 0.0145 0.055 0.2773
Schistosoma mansoni tubulin subunit alpha 0.1171 0.4862 0.7468
Echinococcus granulosus Tubulin beta 2C chain 0.1563 0.6509 1
Echinococcus multilocularis cpg binding protein 0.0096 0.0344 0.034
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Brugia malayi Calcitonin receptor-like protein seb-1 0.021 0.0823 0.1262
Loa Loa (eye worm) SRC-1 0.0049 0.0146 0.0222
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.006
Loa Loa (eye worm) ACC-1 protein 0.0023 0.0036 0.0053
Trypanosoma cruzi MFS transporter, putative 0.0055 0.0174 0.0264
Schistosoma mansoni survival motor neuron protein 0.0048 0.0143 0.0216
Loa Loa (eye worm) hypothetical protein 0.0115 0.0425 0.065
Brugia malayi Cation transporter family protein 0.0023 0.0036 0.0053
Echinococcus granulosus Immunoglobulin 0.0021 0.0029 0.0038
Trichomonas vaginalis tubulin beta chain, putative 0.1171 0.4862 0.7468
Onchocerca volvulus 0.0055 0.0174 0.084
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0067 0.0097
Brugia malayi Cathepsin L-like precursor 0.0017 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0119 0.0443 0.0678
Giardia lamblia Alpha-tubulin 0.1171 0.4862 0.7465
Loa Loa (eye worm) LGC-31 protein 0.0023 0.0036 0.0053
Echinococcus multilocularis tubulin alpha chain 0.1171 0.4862 0.486
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0145
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.011 0.0403 0.0616
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0129 0.0192
Echinococcus multilocularis tubulin alpha 1C chain 0.1171 0.4862 0.486
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0027
Brugia malayi beta-lactamase family protein 0.0145 0.055 0.0842
Brugia malayi Muscleblind-like protein 0.0166 0.0641 0.0982
Echinococcus multilocularis isocitrate dehydrogenase 0.0111 0.0408 0.0403
Treponema pallidum cell division protein FtsZ 0.0396 0.1605 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0872 0.3605 0.5535
Loa Loa (eye worm) hypothetical protein 0.0145 0.055 0.0842
Brugia malayi hypothetical protein 0.0037 0.0096 0.0146
Brugia malayi Myosin head containing protein 0.0037 0.0096 0.0146
Onchocerca volvulus 0.0052 0.0159 0.0761
Echinococcus multilocularis Niemann Pick C1 protein 0.0609 0.25 0.2496
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0054 0.008
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0024 0.0044 0.0166
Echinococcus granulosus c src tyrosine kinase 0.002 0.0024 0.0031
Toxoplasma gondii beta tubulin 0.1563 0.6509 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.018 0.0273
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0072 0.0246 0.1478
Brugia malayi Nuclear hormone receptor family member nhr-40 0.011 0.0403 0.0616
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.005 0.0254
Onchocerca volvulus 0.0023 0.0036 0.0128
Loa Loa (eye worm) tubulin alpha-2 chain 0.1171 0.4862 0.7469
Echinococcus multilocularis GPCR, family 2 0.0066 0.022 0.0216
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Brugia malayi Cell division protein ftsZ 0.0396 0.1605 0.2464
Echinococcus granulosus Solute carrier organic anion transporter family 0.0055 0.0174 0.0261
Trichomonas vaginalis tubulin epsilon chain, putative 0.1171 0.4862 0.7468
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0145 0.055 0.1414
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0011 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0011 0.0004
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0036 0.0049
Brugia malayi Furin-like cysteine rich region family protein 0.0467 0.1903 0.2921
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.022 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0129 0.0192
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0181 0.0272
Echinococcus granulosus bloom syndrome protein 0.0041 0.0113 0.0168
Plasmodium falciparum tubulin beta chain 0.1563 0.6509 1
Brugia malayi hypothetical protein 0.0024 0.0041 0.006
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0609 0.25 0.384
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.01 0.0152
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0101 0.0097
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0085 0.0298 0.0455
Echinococcus granulosus integrin beta 2 0.0231 0.0911 0.1394
Schistosoma mansoni tubulin subunit beta 0.1563 0.6509 1
Leishmania major beta tubulin 0.1563 0.6509 1
Brugia malayi Isocitrate dehydrogenase 0.0111 0.0408 0.0624
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Schistosoma mansoni hypothetical protein 0.0048 0.0143 0.0216
Plasmodium vivax tubulin alpha chain, putative 0.1171 0.4862 0.7469
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.018 0.0273
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0096 0.0141
Echinococcus granulosus tubulin delta chain 0.0396 0.1605 0.2461
Giardia lamblia Alpha-tubulin 0.1171 0.4862 0.7465
Echinococcus granulosus Tubulin alpha 1 chain 0.1171 0.4862 0.7468
Brugia malayi MAP kinase sur-1 0.0057 0.018 0.0274
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0618 0.2539 0.3899
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.055 0.0841
Echinococcus granulosus expressed conserved protein 0.0572 0.2345 0.3598
Toxoplasma gondii patched family protein 0.0037 0.0096 0.0145
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0021
Echinococcus multilocularis tubulin alpha chain 0.1171 0.4862 0.486
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Loa Loa (eye worm) BEN-1 protein 0.1563 0.6509 1
Schistosoma mansoni DNA helicase recq5 0.0028 0.0061 0.009
Echinococcus granulosus beta tubulin 0.1563 0.6509 1
Brugia malayi tubulin alpha-2 chain 0.1171 0.4862 0.7469
Echinococcus multilocularis Tubulin beta 2C chain 0.1563 0.6509 0.6508
Loa Loa (eye worm) hypothetical protein 0.0058 0.0185 0.0282
Schistosoma mansoni tubulin subunit delta 0.0396 0.1605 0.2464
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0047 0.014 0.0213
Schistosoma mansoni nAChR subunit 0.0023 0.0036 0.0052
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0091 0.0133
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.018 0.027
Echinococcus multilocularis tubulin delta chain 0.0396 0.1605 0.1602
Toxoplasma gondii patched family protein 0.0037 0.0096 0.0145
Leishmania major hypothetical protein, conserved 0.0177 0.0685 0.1047
Trichomonas vaginalis conserved hypothetical protein 0.0396 0.1605 0.2461
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.011 0.0403 0.0399
Schistosoma mansoni nuclear receptor nhr-48 0.0052 0.0159 0.0241
Echinococcus multilocularis Tubulin beta 2C chain 0.1563 0.6509 0.6508
Loa Loa (eye worm) hypothetical protein 0.0261 0.1039 0.1594
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0208 0.0815 0.1246
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0023 0.0036 0.0053
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.01 0.0151
Schistosoma mansoni tyrosine kinase 0.0104 0.038 0.0581
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.006
Echinococcus multilocularis nuclear receptor nhr 48 0.0052 0.0159 0.0155
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.015 0.0571 0.0567
Onchocerca volvulus Protein ultraspiracle homolog 0.011 0.0403 0.2017
Mycobacterium leprae Probable lipase LipE 0.0145 0.055 0.3356
Toxoplasma gondii beta-tubulin, putative 0.1563 0.6509 1
Schistosoma mansoni hypothetical protein 0.0066 0.022 0.0335
Mycobacterium tuberculosis Probable hydrolase 0.0145 0.055 0.1414
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0392 0.2366
Echinococcus multilocularis integrin alpha ps 0.0068 0.0228 0.0224
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0072 0.0246 1
Echinococcus granulosus geminin 0.1378 0.5735 0.881
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0036
Loa Loa (eye worm) glutaminase 0.029 0.116 0.178
Brugia malayi hypothetical protein 0.0177 0.0685 0.105
Brugia malayi MH2 domain containing protein 0.0024 0.0043 0.0063
Echinococcus multilocularis tubulin subunit beta 0.1563 0.6509 0.6508
Brugia malayi Nuclear hormone receptor family member nhr-19 0.011 0.0403 0.0616
Entamoeba histolytica recQ family DNA helicase 0.0015 0.0002 0.0004
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0059 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.004 0.0056
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.018 0.0176
Brugia malayi beta-lactamase 0.0145 0.055 0.0842
Leishmania major beta tubulin 0.1563 0.6509 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0217 0.0213
Plasmodium vivax patched family protein, putative 0.0037 0.0096 0.0148
Echinococcus multilocularis Tubulin alpha 1 chain 0.1171 0.4862 0.486
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0072 0.0246 0.1518
Trichomonas vaginalis tubulin alpha chain, putative 0.0476 0.1941 0.2977
Loa Loa (eye worm) TK/ABL protein kinase 0.0218 0.0859 0.1317
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0024 0.0042 0.0057
Echinococcus granulosus tm gpcr rhodopsin 0.0528 0.2162 0.3317
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0023 0.0036 0.0049
Echinococcus multilocularis thyroid hormone receptor alpha 0.0235 0.0929 0.0925
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0118 0.0175
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0049 0.0146 0.0218
Schistosoma mansoni tubulin subunit beta 0.1563 0.6509 1
Onchocerca volvulus 0.0055 0.0174 0.084
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0023 0.0036 0.0032
Schistosoma mansoni coup transcription factor 0.011 0.0403 0.0615
Trichomonas vaginalis tubulin beta chain, putative 0.0476 0.1941 0.2977
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0118 0.0114
Brugia malayi isocitrate dehydrogenase 0.0111 0.0408 0.0624
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0036 0.0053
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0049 0.0146 0.0142
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0018 0.0016 0.004
Echinococcus granulosus tubulin subunit TubB 0.1171 0.4862 0.7468
Loa Loa (eye worm) isocitrate dehydrogenase 0.0111 0.0408 0.0624
Brugia malayi Patched related family protein 4 0.0037 0.0096 0.0146
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0024 0.0044 0.006
Schistosoma mansoni nAChR subunit 0.0023 0.0036 0.0052
Loa Loa (eye worm) glutaminase 2 0.029 0.116 0.178
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0023 0.0036 0.0053
Echinococcus multilocularis hypothetical protein 0.1171 0.4862 0.486
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.011 0.0403 0.0399
Echinococcus multilocularis nAChR subunit 0.0023 0.0036 0.0032
Echinococcus granulosus muscleblind protein 0.0166 0.0641 0.0979
Echinococcus granulosus tubulin gamma 1 chain 0.0925 0.3829 0.5879
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0139 0.0207
Trichomonas vaginalis tubulin alpha chain, putative 0.0476 0.1941 0.2977
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0113 0.0172
Echinococcus granulosus sterol regulatory element binding protein 0.0261 0.1039 0.1591
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.011 0.0403 0.0615
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0645 0.0985
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0023 0.0036 0.0049
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0092 0.0088
Brugia malayi Tubulin beta chain 0.0396 0.1605 0.2464
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0091
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0018 0.0016 0.0017
Trypanosoma cruzi zeta tubulin, putative 0.0946 0.3916 0.6015
Loa Loa (eye worm) hypothetical protein 0.0038 0.01 0.0152
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0443 0.1133
Echinococcus multilocularis agrin 0.0038 0.01 0.0096
Loa Loa (eye worm) hypothetical protein 0.011 0.0403 0.0616
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0217 0.033
Loa Loa (eye worm) agrin synaptic family protein 0.0038 0.01 0.0152
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.01 0.0152
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Trypanosoma brucei zeta tubulin, putative 0.0946 0.3916 0.6014
Brugia malayi Fibronectin type III domain containing protein 0.0024 0.0041 0.006
Mycobacterium ulcerans esterase/lipase LipP 0.0145 0.055 0.3383
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0061 0.0079
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0036 0.0052
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0159 0.0241
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1014 0.1552
Loa Loa (eye worm) tubulin beta-4 chain 0.1563 0.6509 1
Trypanosoma cruzi epsilon tubulin, putative 0.0924 0.3825 0.5875
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Brugia malayi nuclear receptor RXR 0.0058 0.0185 0.0282
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0011 0.0014
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.1014 0.1555
Loa Loa (eye worm) hypothetical protein 0.0066 0.022 0.0336
Echinococcus multilocularis c src tyrosine kinase 0.002 0.0024 0.002
Trypanosoma brucei trypanothione reductase 0.0047 0.0139 0.0207
Schistosoma mansoni hypothetical protein 0.0252 0.1 0.1533
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0023 0.0036 0.0049
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.055 0.0838
Onchocerca volvulus 0.0023 0.0036 0.0128
Loa Loa (eye worm) hypothetical protein 0.011 0.0403 0.0616
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0104 0.038 0.0578
Trypanosoma brucei beta tubulin 0.1563 0.6509 1
Onchocerca volvulus 0.0027 0.0054 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0059
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.018 0.027
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0139 0.0338
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.018 0.027
Echinococcus granulosus tubulin alpha chain 0.1171 0.4862 0.7468
Leishmania major epsilon tubulin, putative 0.0924 0.3825 0.5874
Mycobacterium ulcerans cell division protein FtsZ 0.0396 0.1605 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.001 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Echinococcus granulosus tubulin beta 4A class IVa 0.1563 0.6509 1
Loa Loa (eye worm) hypothetical protein 0.0143 0.0544 0.0833
Leishmania major beta tubulin 0.1563 0.6509 1
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.005 0.0074
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0129 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0059
Echinococcus multilocularis expressed protein 0.0018 0.0016 0.0012
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0042 0.006
Mycobacterium ulcerans hypothetical protein 0.0024 0.004 0.0192
Loa Loa (eye worm) hypothetical protein 0.0058 0.0185 0.0282
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0775 0.3198 0.4912
Brugia malayi Cation transporter family protein 0.0023 0.0036 0.0053
Loa Loa (eye worm) hypothetical protein 0.0145 0.055 0.0842
Schistosoma mansoni smad 0.0024 0.0043 0.0062
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0011 0.0011
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.018 0.0273
Trichomonas vaginalis tubulin epsilon chain, putative 0.1563 0.6509 1
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0129 0.0192
Schistosoma mansoni agrin 0.0038 0.01 0.0151
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0261 0.1039 0.1594
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0011 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.018 0.0273
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0924 0.3827 1
Onchocerca volvulus 0.0023 0.0036 0.0128
Echinococcus granulosus tubulin alpha 3 chain 0.1171 0.4862 0.7468
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0081
Echinococcus granulosus Niemann Pick C1 protein 0.0609 0.25 0.3836
Treponema pallidum NADH oxidase 0.0016 0.001 0.0047
Onchocerca volvulus 0.0037 0.0096 0.0439
Brugia malayi Nuclear hormone receptor family member nhr-14 0.011 0.0403 0.0616
Loa Loa (eye worm) hypothetical protein 0.0166 0.0641 0.0982
Loa Loa (eye worm) pigment dispersing factor receptor c 0.021 0.0823 0.1262
Onchocerca volvulus Protein patched homolog 0.0037 0.0096 0.0439
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.004 0.0192
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0645 0.0985
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.004 0.0192
Entamoeba histolytica tubulin alpha-1 chain 0.1171 0.4862 0.7469
Giardia lamblia GTOR 0.0045 0.0129 0.0184
Echinococcus granulosus dnaJ subfamily B 0.0863 0.3567 0.5476
Loa Loa (eye worm) hypothetical protein 0.0027 0.0054 0.008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0049 0.0146 0.0142
Echinococcus multilocularis tyrosine protein kinase Srms 0.0042 0.0118 0.0114
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0181 0.0272
Loa Loa (eye worm) hypoxia-induced factor 1 0.015 0.0571 0.0874
Echinococcus multilocularis dnaJ subfamily B 0.0863 0.3567 0.3564
Echinococcus granulosus tubulin alpha chain 0.1171 0.4862 0.7468
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.01 0.0151
Schistosoma mansoni tyrosine kinase 0.0152 0.0579 0.0886
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0091 0.0133
Schistosoma mansoni tubulin subunit beta 0.1563 0.6509 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0103 0.0143
Echinococcus granulosus tyrosine kinase 0.0042 0.0118 0.0175
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Brugia malayi SPARC precursor 0.0038 0.01 0.0152
Loa Loa (eye worm) RecQ helicase 0.0041 0.0113 0.0172
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0023 0.0036 0.0032
Loa Loa (eye worm) hypothetical protein 0.0035 0.0091 0.0136
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0217 0.033
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.001 0.0008
Echinococcus granulosus cathepsin l1 0.0017 0.0011 0.0011
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.004 0.0192
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.001 0.0012
Schistosoma mansoni ferritin 0.0018 0.0016 0.0021
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0052 0.0159 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0091 0.0133
Echinococcus granulosus L aminoadipate semialdehyde 0.0257 0.1024 0.1567
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0185 0.0282
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.011 0.0403 0.0399
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0257 0.1024 0.1569
Onchocerca volvulus 0.0048 0.0143 0.0678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0111 0.0408 0.1042
Loa Loa (eye worm) transcription factor SMAD2 0.0354 0.1428 0.2192
Plasmodium falciparum ataxin-2 like protein, putative 0.0177 0.0685 0.1039
Brugia malayi ecdysone receptor 0.0052 0.0159 0.0242
Trypanosoma brucei beta tubulin 0.1563 0.6509 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.022 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.009 0.0086
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0217 0.033
Loa Loa (eye worm) hypothetical protein 0.0024 0.004 0.0059
Brugia malayi orphan nuclear receptor NR2E1 0.0052 0.0159 0.0242
Schistosoma mansoni ferritin light chain 0.0018 0.0016 0.0021
Echinococcus multilocularis neuroglian 0.0024 0.0041 0.0037
Loa Loa (eye worm) hypothetical protein 0.0024 0.004 0.0059
Echinococcus granulosus FTZ F1 alpha 0.011 0.0403 0.0613
Schistosoma mansoni hypothetical protein 0.0252 0.1 0.1533
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0159 0.0242
Echinococcus multilocularis smad 0.0024 0.0043 0.0038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0001
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0155 0.0591 0.0902
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0139 0.0135
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Schistosoma mansoni DNA helicase recq1 0.0028 0.0061 0.009
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0043 0.0062
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0061 0.0057
Schistosoma mansoni integrin alpha-ps 0.0035 0.0091 0.0136
Echinococcus multilocularis tubulin subunit TubB 0.1171 0.4862 0.486
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0096 0.0144
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0024 0.0044 0.006
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0052 0.0077
Brugia malayi Tubulin beta-1 chain 0.1563 0.6509 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0043 0.0059
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0004 0.0004
Onchocerca volvulus Putative nachr subunit 0.0023 0.0036 0.0128
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Giardia lamblia Beta tubulin 0.1563 0.6509 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0332 0.0507
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0091 0.0133
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0023 0.0036 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0683 0.1043
Mycobacterium tuberculosis Probable lipase LipD 0.0145 0.055 0.1414
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0036 0.0049
Plasmodium vivax delta tubulin, putative 0.0396 0.1605 0.2466
Trypanosoma cruzi PAB1-binding protein , putative 0.0177 0.0685 0.1049
Echinococcus multilocularis tubulin alpha 3 chain 0.1171 0.4862 0.486
Onchocerca volvulus Bile acid receptor homolog 0.011 0.0403 0.2017
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0145 0.055 0.0842
Brugia malayi ecdysteroid receptor 0.011 0.0403 0.0616
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0011 0.0017
Loa Loa (eye worm) beta-lactamase 0.0145 0.055 0.0842
Onchocerca volvulus 0.0055 0.0174 0.084
Onchocerca volvulus 0.0024 0.004 0.015
Schistosoma mansoni retinoic acid receptor RXR 0.0208 0.0815 0.1249
Brugia malayi protein C24B5.3 0.0037 0.0096 0.0146
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Treponema pallidum ATP-dependent RNA helicase 0.0024 0.0044 0.0257
Echinococcus granulosus tubulin alpha chain 0.1171 0.4862 0.7468
Brugia malayi nuclear receptor NHR-67 0.0052 0.0159 0.0242
Echinococcus granulosus tyrosine protein kinase Lyn 0.0049 0.0148 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0024 0.0044 0.0088
Loa Loa (eye worm) tubulin alpha 2 0.0299 0.1199 0.1839
Loa Loa (eye worm) patched family protein 0.0037 0.0096 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Brugia malayi conserved hypotetical protein 0.0052 0.0159 0.0242
Schistosoma mansoni tubulin subunit epsilon 0.0924 0.3825 0.5875
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0111 0.0408 0.0623
Loa Loa (eye worm) hypothetical protein 0.011 0.0403 0.0616
Loa Loa (eye worm) hypothetical protein 0.011 0.0403 0.0616
Loa Loa (eye worm) hypothetical protein 0.0145 0.055 0.0842
Loa Loa (eye worm) hypothetical protein 0.0027 0.0054 0.008
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0104 0.0144
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0011 0.0007
Schistosoma mansoni integrin alpha 0.0152 0.0581 0.0889
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0061 0.0087
Onchocerca volvulus 0.0023 0.0036 0.0128
Loa Loa (eye worm) hypothetical protein 0.0038 0.01 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Schistosoma mansoni ferritin 0.0018 0.0016 0.0021
Brugia malayi hypothetical protein 0.0114 0.0422 0.0645
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0023 0.0036 0.0049
Trypanosoma brucei epsilon tubulin 0.0872 0.3605 0.5535
Loa Loa (eye worm) hypothetical protein 0.1171 0.4862 0.7469
Trypanosoma brucei cytochrome P450, putative 0.0026 0.005 0.0071
Onchocerca volvulus 0.0027 0.0054 0.022
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0159 0.0761
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.002 0.0024 0.002
Toxoplasma gondii protease inhibitor PI2 0.0038 0.01 0.0151
Loa Loa (eye worm) acetyltransferase 0.0143 0.0543 0.0832
Loa Loa (eye worm) CYP4Cod1 0.0026 0.005 0.0075
Echinococcus granulosus tyrosine protein kinase Fyn 0.0049 0.0146 0.0218
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0104 0.038 0.0376
Onchocerca volvulus 0.0037 0.0096 0.0439
Loa Loa (eye worm) integrin beta-2 0.0311 0.1251 0.1919
Onchocerca volvulus 0.0055 0.0174 0.084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0041 0.006
Entamoeba histolytica tubulin alpha chain, putative 0.1171 0.4862 0.7469
Leishmania major zeta tubulin, putative 0.0946 0.3916 0.6014
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0159 0.0238
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0024 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Echinococcus granulosus tumor protein p63 0.0336 0.1354 0.2074
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0011 0.0011
Schistosoma mansoni nAChR subunit 0.0023 0.0036 0.0052
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0111 0.0408 0.0612
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.0044 0.0067
Schistosoma mansoni hypothetical protein 0.0079 0.0275 0.0419
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.001 0.0012
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0043 0.0059
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.004 0.0062
Entamoeba histolytica hypothetical protein 0.0071 0.0241 0.037
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0217 0.0327
Schistosoma mansoni tyrosine kinase 0.0049 0.0146 0.0221
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0113 0.0168
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0332 0.0507
Trichomonas vaginalis tubulin, putative 0.1563 0.6509 1
Trypanosoma brucei protein kinase, putative 0.0057 0.018 0.027
Brugia malayi Nuclear hormone receptor-like 1 0.011 0.0403 0.0616
Echinococcus multilocularis Tubulin beta 2C chain 0.1563 0.6509 0.6508
Echinococcus multilocularis integrin alpha 3 0.0117 0.0431 0.0427
Echinococcus granulosus Tubulin beta 2C chain 0.1563 0.6509 1
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0092 0.0514
Schistosoma mansoni alpha tubulin 0.1171 0.4862 0.7468
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.004 0.008
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.011 0.0403 0.0613
Echinococcus multilocularis tyrosine protein kinase Blk 0.0042 0.0118 0.0114
Brugia malayi steroid hormone receptor 0.011 0.0403 0.0616
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0011 0.0017
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0023 0.0036 0.0053
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0079 0.0275 0.0416
Onchocerca volvulus 0.0037 0.0096 0.0439
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0443 0.1133
Echinococcus granulosus tyrosine protein kinase Fyn 0.0049 0.0146 0.0218
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0028 0.0036
Toxoplasma gondii LsmAD domain-containing protein 0.0177 0.0685 0.1049
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.018 0.0274
Plasmodium falciparum tubulin gamma chain 0.0925 0.3829 0.5876
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0096 0.0141
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.018 0.027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0036 0.0049
Schistosoma mansoni hypothetical protein 0.1378 0.5735 0.8811
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0024 0.0044 0.0039
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.001 0.0012
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0181 0.0275
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0044 0.006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0036 0.0053
Loa Loa (eye worm) hypothetical protein 0.011 0.0403 0.0616
Echinococcus granulosus Tubulin beta 2C chain 0.1563 0.6509 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0012
Onchocerca volvulus 0.0055 0.0174 0.084
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0043 0.0063
Brugia malayi Cathepsin L-like precursor 0.0017 0.0011 0.0015
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0059 0.0055
Echinococcus multilocularis geminin 0.1378 0.5735 0.5733
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0036 0.0032
Echinococcus granulosus neuropeptide s receptor 0.0471 0.1922 0.2948
Trypanosoma cruzi PAB1-binding protein , putative 0.0177 0.0685 0.1049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Mycobacterium ulcerans glutaminase 0.029 0.116 0.7209
Echinococcus granulosus tubulin alpha 3 chain 0.1171 0.4862 0.7468
Brugia malayi Tyrosine-protein kinase abl-1 0.0098 0.0354 0.0541
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.055 0.0838
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0011 0.0011
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Brugia malayi hypothetical protein 0.0037 0.0096 0.0146
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0725 0.2988 0.4588
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0044 0.006
Trichomonas vaginalis tubulin epsilon chain, putative 0.1563 0.6509 1
Echinococcus granulosus cpg binding protein 0.0096 0.0344 0.0522
Schistosoma mansoni tyrosine kinase 0.0246 0.0975 0.1496
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.004 0.0062
Echinococcus granulosus integrin alpha 3 0.0117 0.0431 0.0656
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.01 0.0151
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0055 0.0174 0.0265
Trichomonas vaginalis tubulin beta chain, putative 0.1171 0.4862 0.7468
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.001 0.0008
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0159 0.0238
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0478 0.1952 0.2997
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Leishmania major beta tubulin 0.1563 0.6509 1
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1563 0.6509 0.6508
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.011 0.0403 0.0616
Echinococcus granulosus glycine receptor subunit beta 0.0023 0.0036 0.0049
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0055 0.0174 0.0261
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Loa Loa (eye worm) hypothetical protein 0.0027 0.0054 0.008
Brugia malayi tubulin alpha chain - mouse 0.1171 0.4862 0.7469
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1014 0.1552
Echinococcus multilocularis Immunoglobulin 0.0021 0.0029 0.0025
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0129 0.0195
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0139 0.0211
Loa Loa (eye worm) glutathione reductase 0.0047 0.0139 0.0211
Echinococcus granulosus neuropeptide receptor A26 0.0471 0.1922 0.2948
Loa Loa (eye worm) hypothetical protein 0.011 0.0403 0.0616
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0645 0.3265
Brugia malayi Nuclear hormone receptor family member nhr-31 0.011 0.0403 0.0616
Leishmania major beta tubulin 0.1563 0.6509 1
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0174 0.084
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0061 0.0057
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0072 0.0246 0.1478
Leishmania major cathepsin L-like protease 0.0017 0.0011 0.0011
Echinococcus multilocularis Tubulin alpha 1 chain 0.1171 0.4862 0.486
Trichomonas vaginalis helicase, putative 0.0021 0.0028 0.0036
Loa Loa (eye worm) tubulin beta chain 0.1563 0.6509 1
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0055 0.0174 0.017
Echinococcus granulosus ecdysone induced protein 78C 0.011 0.0403 0.0613
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.011 0.0403 0.0615
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0011 0.0011
Mycobacterium ulcerans lipase LipD 0.0145 0.055 0.3383
Schistosoma mansoni tubulin subunit beta 0.0396 0.1605 0.2464
Echinococcus multilocularis lamin dm0 0.0027 0.0054 0.005
Brugia malayi Tubulin alpha chain 0.1171 0.4862 0.7469
Brugia malayi photoreceptor-specific nuclear receptor 0.011 0.0403 0.0616
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0081 0.0118
Brugia malayi Thioredoxin reductase 0.0047 0.0139 0.0211
Schistosoma mansoni RAR-like nuclear receptor 0.011 0.0403 0.0615
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Echinococcus granulosus tubulin alpha chain 0.1171 0.4862 0.7468
Echinococcus multilocularis muscleblind protein 1 0.0166 0.0641 0.0637
Onchocerca volvulus 0.0023 0.0036 0.0128
Brugia malayi hypothetical protein 0.0052 0.0159 0.0242
Leishmania major beta tubulin 0.1563 0.6509 1
Schistosoma mansoni nAChR subunit 0.0023 0.0036 0.0052
Brugia malayi Smad1 0.0024 0.0043 0.0063
Echinococcus multilocularis expressed conserved protein 0.0572 0.2345 0.2341
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0091 0.0133
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0058 0.0185 0.0281
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.001 0.0008
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0052 0.0159 0.0241
Brugia malayi hypothetical protein 0.0055 0.0174 0.0265
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0129 0.0192
Echinococcus multilocularis insulin receptor 0.0152 0.0579 0.0575
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.0543 0.0539
Echinococcus multilocularis roundabout 2 0.003 0.0066 0.0062
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.018 0.0262
Schistosoma mansoni single-minded 0.0048 0.0145 0.0219
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.004 0.0192
Echinococcus multilocularis tubulin beta 1 chain 0.1563 0.6509 0.6508
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0023 0.0036 0.0052
Giardia lamblia Beta tubulin 0.1563 0.6509 1
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0054 0.008
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0159 0.0155
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0023 0.0036 0.0032
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0021 0.0029 0.0025
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Leishmania major beta tubulin 0.1563 0.6509 1
Trypanosoma cruzi tubulin delta chain 0.0725 0.2988 0.4588
Schistosoma mansoni tubulin subunit alpha 0.1171 0.4862 0.7468
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0023 0.0036 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.018 0.0273
Schistosoma mansoni hypothetical protein 0.0143 0.0544 0.0833
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0104 0.0159
Echinococcus granulosus Protein patched homolog 1 0.0261 0.1039 0.1591
Trypanosoma brucei PAB1-binding protein , putative 0.0177 0.0685 0.1047
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0159 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-1 0.011 0.0403 0.0616
Schistosoma mansoni tyrosine kinase 0.002 0.0024 0.0034
Loa Loa (eye worm) tubulin beta chain 0.0396 0.1605 0.2464
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0036 0.0049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0036 0.0053
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0061 0.0091
Echinococcus multilocularis beta LACTamase domain containing family member 0.0145 0.055 0.0545
Echinococcus multilocularis lamin 0.0027 0.0054 0.005
Schistosoma mansoni cpg binding protein 0.0096 0.0344 0.0525
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0061 0.009
Echinococcus granulosus Tubulin beta 2C chain 0.1563 0.6509 1
Leishmania major alpha tubulin 0.1171 0.4862 0.7468
Brugia malayi beta-tubulin, identical 0.1563 0.6509 1
Brugia malayi MH1 domain containing protein 0.0024 0.0043 0.0063
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0015 0.0009
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.001 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Echinococcus granulosus tyrosine protein kinase Src64B 0.0049 0.0146 0.0218
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0081 0.0118
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.004 0.0056
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Plasmodium falciparum ataxin-2 like protein, putative 0.0177 0.0685 0.1039
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0036
Loa Loa (eye worm) hypothetical protein 0.032 0.1286 0.1974
Loa Loa (eye worm) cysteine protease 0.0017 0.0011 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0028 0.0036
Echinococcus granulosus integrin alpha ps 0.0068 0.0228 0.0344
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.011 0.0403 0.0399
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0011 0.0002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0332 0.0504
Schistosoma mansoni tubulin subunit alpha 0.0396 0.1605 0.2464
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0023 0.0036 0.0032
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.001 0.0012
Schistosoma mansoni tyrosine kinase 0.0246 0.0975 0.1496
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0174 0.084
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0181 0.0276
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0092 0.0087
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.018 0.0273
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.018 0.027
Onchocerca volvulus 0.0036 0.0092 0.0415
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0028 0.0036
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.004 0.0152
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.011 0.0403 0.0399
Loa Loa (eye worm) TK/KIN16 protein kinase 0.003 0.0068 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0072 0.0246 0.0377
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0024 0.0044 0.0067
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0054 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1014 0.1552
Brugia malayi protein C24B5.3 0.0037 0.0096 0.0146
Leishmania major cathepsin L-like protease 0.0017 0.0011 0.0011
Echinococcus multilocularis Tubulin alpha 1 chain 0.1171 0.4862 0.486
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0012
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0023 0.0036 0.0053
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0159 0.0155
Trichomonas vaginalis tubulin gamma chain, putative 0.0924 0.3825 0.5874
Loa Loa (eye worm) hypothetical protein 0.0024 0.0042 0.0061
Schistosoma mansoni nAChR subunit 0.0023 0.0036 0.0052
Echinococcus multilocularis integrin alpha ps 0.0033 0.0079 0.0074
Schistosoma mansoni hypothetical protein 0.0125 0.0468 0.0715
Brugia malayi AMP-binding enzyme family protein 0.0024 0.004 0.0059
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.022 0.0332
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.003 0.004
Loa Loa (eye worm) ctsf protein 0.0017 0.0011 0.0015
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.1014 0.1555
Mycobacterium ulcerans bacterioferritin BfrB 0.0018 0.0016 0.004
Schistosoma mansoni intermediate filament proteins 0.0027 0.0054 0.008
Brugia malayi Nuclear hormone receptor family member nhr-3 0.011 0.0403 0.0616
Brugia malayi Cation transporter family protein 0.0023 0.0036 0.0053
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0072 0.0246 0.0618
Toxoplasma gondii histone lysine methyltransferase SET1 0.0175 0.0677 0.1037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0332 0.0328
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0019 0.0023
Schistosoma mansoni smad1 5 8 and 0.0024 0.0043 0.0062
Echinococcus multilocularis neuropeptide s receptor 0.0471 0.1922 0.1918
Schistosoma mansoni nAChR subunit 0.0023 0.0036 0.0052
Echinococcus multilocularis glycine receptor subunit beta 0.0023 0.0036 0.0032
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Mycobacterium tuberculosis Conserved protein 0.0145 0.055 0.1414
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0332 0.0504
Brugia malayi Patched related family protein 12 0.0037 0.0096 0.0146
Echinococcus multilocularis protein dispatched 1 0.0298 0.1194 0.1191
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0044 0.006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0192 0.0749 0.1147
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Brugia malayi nuclear hormone receptor family member odr-7 0.0052 0.0159 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0052 0.0074
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0058 0.0185 0.0278
Schistosoma mansoni organic anion transporter 0.0055 0.0174 0.0264
Schistosoma mansoni hypothetical protein 0.0863 0.3567 0.5478
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Mycobacterium leprae conserved hypothetical protein 0.0145 0.055 0.3356
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0061 0.0087
Trichomonas vaginalis tubulin, putative 0.0449 0.1829 0.2805
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.018 0.027
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0129 0.0198
Echinococcus granulosus GPCR family 2 0.0066 0.022 0.0332
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Schistosoma mansoni alpha tubulin 0.1171 0.4862 0.7468
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0044 0.0063
Loa Loa (eye worm) DR-78 0.0052 0.0159 0.0242
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0072 0.0104
Mycobacterium tuberculosis Probable reductase 0.0107 0.0392 0.1002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Trypanosoma brucei hypothetical protein, conserved 0.0145 0.055 0.0838
Schistosoma mansoni patched 1 0.0261 0.1039 0.1594
Entamoeba histolytica tubulin family protein 0.1563 0.6509 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0052 0.0159 0.0238
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Loa Loa (eye worm) MH2 domain-containing protein 0.0354 0.1428 0.2192
Plasmodium falciparum tubulin delta chain, putative 0.0396 0.1605 0.2455
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0111 0.0408 0.062
Brugia malayi secreted modular calcium-binding protein 1 0.0038 0.01 0.0152
Loa Loa (eye worm) hypothetical protein 0.021 0.0823 0.1262
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.055 0.0838
Loa Loa (eye worm) hypothetical protein 0.0235 0.093 0.1426
Schistosoma mansoni cell adhesion molecule 0.0027 0.0054 0.0079
Schistosoma mansoni hypothetical protein 0.0066 0.022 0.0335
Schistosoma mansoni nephrin 0.0027 0.0053 0.0078
Loa Loa (eye worm) hypothetical protein 0.0145 0.055 0.0842
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0392 0.1002
Echinococcus granulosus tyrosine protein kinase ABL1 0.0218 0.0859 0.1314
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.001 0.0008
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0072 0.0246 0.0363
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0242
Schistosoma mansoni tubulin subunit beta 0.1563 0.6509 1
Echinococcus granulosus twitchin 0.0024 0.0043 0.006
Entamoeba histolytica hypothetical protein 0.0071 0.0241 0.037
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0023 0.0036 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0081 0.0118
Brugia malayi Cathepsin L-like precursor 0.0017 0.0011 0.0015
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0055 0.0174 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0036
Brugia malayi hypothetical protein 0.0055 0.0174 0.0265
Brugia malayi Integrin alpha pat-2 precursor 0.0152 0.0581 0.0889
Echinococcus multilocularis muscleblind protein 0.0166 0.0641 0.0637
Loa Loa (eye worm) hypothetical protein 0.011 0.0403 0.0616
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0015 0.0024
Trichomonas vaginalis tubulin beta chain, putative 0.1171 0.4862 0.7468
Echinococcus granulosus single minded 2 0.0036 0.0092 0.0135
Plasmodium vivax ataxin-2 like protein, putative 0.0177 0.0685 0.1053
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.011 0.0403 0.0399
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0332 0.0508
Echinococcus multilocularis beta tubulin 0.1563 0.6509 0.6508
Echinococcus multilocularis tyrosine protein kinase Abl 0.0098 0.0354 0.035
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Loa Loa (eye worm) hypothetical protein 0.0058 0.0185 0.0282
Trichomonas vaginalis tubulin epsilon chain, putative 0.0396 0.1605 0.2461
Echinococcus granulosus lamin dm0 0.0027 0.0054 0.0076
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0004 0.0004
Leishmania major beta tubulin 0.1563 0.6509 1
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0101 0.0149
Loa Loa (eye worm) hypothetical protein 0.0055 0.0174 0.0265
Brugia malayi glutathione reductase 0.0047 0.0139 0.0211
Echinococcus multilocularis integrin alpha ps 0.0068 0.0228 0.0224
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0021
Brugia malayi excitatory GABA receptor EXP-1A 0.0023 0.0036 0.0053
Leishmania major beta tubulin 0.1563 0.6509 1
Echinococcus granulosus epidermal growth factor receptor 0.0252 0.1002 0.1534
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Loa Loa (eye worm) tubulin alpha-3 chain 0.0695 0.2863 0.4396
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.0468 0.0463
Leishmania major cathepsin L-like protease 0.0017 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0252 0.1 0.1533
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0181 0.1074
Brugia malayi Cathepsin L-like precursor 0.0017 0.0011 0.0015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0528 0.2162 0.2159
Leishmania major cathepsin L-like protease 0.0017 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0252 0.1 0.1533
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Trypanosoma cruzi tubulin gamma chain 0.0925 0.3829 0.588
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0054 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0052 0.0074
Trypanosoma brucei epsilon tubulin 0.0924 0.3825 0.5874
Echinococcus granulosus tyrosine protein kinase Blk 0.0042 0.0118 0.0175
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.011 0.0403 0.0616
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0165 0.0251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0059
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.004 0.0056
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0049 0.0146 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0028 0.0036
Plasmodium falciparum glutathione reductase 0.0047 0.0139 0.0199
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0096 0.0144
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0021
Loa Loa (eye worm) hypothetical protein 0.0225 0.0886 0.1359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0063 0.0091
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0111 0.0408 0.0403
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0049 0.0146 0.0142
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0011 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Echinococcus granulosus peroxisome assembly protein 26 0.1171 0.4862 0.7468
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0021
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0208 0.0316
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0332 0.0507
Loa Loa (eye worm) hypothetical protein 0.0058 0.0185 0.0282
Leishmania major beta tubulin 0.1563 0.6509 1
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0061 0.0079
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0129 0.0195
Brugia malayi sulfakinin receptor protein 0.0225 0.0886 0.1359
Schistosoma mansoni ferritin light chain 0.0018 0.0016 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0111 0.0408 0.0403
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0208 0.0313
Loa Loa (eye worm) tubulin alpha chain 0.1171 0.4862 0.7469
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0042 0.0118 0.0175
Plasmodium falciparum eukaryotic initiation factor 4A 0.0024 0.0044 0.0052
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.011 0.0403 0.2017
Onchocerca volvulus 0.0476 0.1941 0.994
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0023 0.0036 0.0053
Brugia malayi hypothetical protein 0.0058 0.0185 0.0282
Loa Loa (eye worm) hypothetical protein 0.0145 0.055 0.0842
Brugia malayi Tubulin gamma chain 0.0925 0.3829 0.5881
Onchocerca volvulus 0.0037 0.0096 0.0439
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0072 0.0246 0.0374
Brugia malayi CHE-14 protein 0.0261 0.1039 0.1594
Trypanosoma brucei beta tubulin 0.1563 0.6509 1
Schistosoma mansoni nuclear hormone receptor 0.011 0.0403 0.0615
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0246 0.1444
Echinococcus granulosus follistatin 0.0038 0.01 0.0148
Schistosoma mansoni retinoid-x-receptor (RXR) 0.011 0.0403 0.0615
Echinococcus granulosus roundabout 2 0.003 0.0066 0.0095
Mycobacterium tuberculosis Probable esterase LipL 0.0145 0.055 0.1414
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0058 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0645 0.0985
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Loa Loa (eye worm) patched family protein 0.0037 0.0096 0.0146
Brugia malayi hypothetical protein 0.0058 0.0185 0.0282
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0208 0.0316
Loa Loa (eye worm) hypothetical protein 0.0609 0.25 0.3839
Schistosoma mansoni cpg binding protein 0.0096 0.0344 0.0525
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0036 0.0032
Trichomonas vaginalis tubulin gamma chain, putative 0.0396 0.1605 0.2461
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0023 0.0036 0.0052
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0015 0.0236
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.01 0.0152
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0053
Brugia malayi Cytochrome P450 family protein 0.0026 0.005 0.0075
Brugia malayi Tubulin alpha-2 chain 0.1171 0.4862 0.7469
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0217 0.0327
Loa Loa (eye worm) hypothetical protein 0.0055 0.0174 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0036
Echinococcus granulosus tubulin epsilon chain 0.0924 0.3825 0.5874
Echinococcus granulosus tubulin subunit beta 0.1563 0.6509 1
Onchocerca volvulus 0.0052 0.0159 0.0761
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0096 0.0132
Loa Loa (eye worm) hypothetical protein 0.0695 0.2863 0.4396
Onchocerca volvulus 0.011 0.0403 0.2017
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0023 0.0036 0.0053
Brugia malayi Steroid receptor seven-up type 2 0.011 0.0403 0.0616
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0011 0.0011
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0081 0.0121
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0111 0.0408 0.062
Echinococcus granulosus tubulin alpha 1C chain 0.1171 0.4862 0.7468
Echinococcus granulosus tyrosine protein kinase Fyn 0.0049 0.0146 0.0218
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0023 0.0036 0.0032
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0174 0.084
Echinococcus multilocularis tubulin alpha 1C chain 0.1171 0.4862 0.486
Schistosoma mansoni thyroid hormone receptor 0.0235 0.0929 0.1424
Schistosoma mansoni hypothetical protein 0.0071 0.0241 0.0367
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0217 0.0334
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0252 0.1002 0.1534
Schistosoma mansoni tyrosine kinase 0.0152 0.0579 0.0886
Leishmania major beta tubulin 0.1563 0.6509 1
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0645 0.0985
Trichomonas vaginalis tubulin alpha chain, putative 0.0476 0.1941 0.2977
Brugia malayi Tubulin alpha chain 0.0396 0.1605 0.2464
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0096 0.0092
Entamoeba histolytica hypothetical protein 0.0071 0.0241 0.037
Loa Loa (eye worm) hypothetical protein 0.0037 0.0096 0.0146
Echinococcus multilocularis cysteine protease 0.0017 0.0011 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0021
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0151 0.0228
Echinococcus multilocularis neuropeptide receptor A26 0.0471 0.1922 0.1918
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.018 0.0176
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0145 0.055 0.1414
Giardia lamblia Beta tubulin 0.1563 0.6509 1
Loa Loa (eye worm) hypothetical protein 0.0166 0.0641 0.0982
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.0526 0.0803
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.018 0.027
Brugia malayi Patched family protein 0.0037 0.0096 0.0146
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0129 0.0125
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.011 0.0403 0.0616
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0052 0.0159 0.0242
Loa Loa (eye worm) CXXC zinc finger family protein 0.0091 0.0322 0.0492
Schistosoma mansoni follistatin 0.0038 0.01 0.0151
Loa Loa (eye worm) hypothetical protein 0.0055 0.0174 0.0265
Echinococcus multilocularis cysteine protease 0.0017 0.0011 0.0007
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.004 0.0062
Schistosoma mansoni thyroid hormone receptor 0.0235 0.0929 0.1424
Echinococcus multilocularis L aminoadipate semialdehyde 0.0257 0.1024 0.102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0102 0.015
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0044 0.006
Entamoeba histolytica hypothetical protein 0.0071 0.0241 0.037
Trypanosoma brucei tubulin gamma chain 0.0925 0.3829 0.5879
Trypanosoma brucei epsilon tubulin 0.0924 0.3825 0.5874
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.093 0.1423
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0174 0.0265
Trichomonas vaginalis tubulin gamma chain, putative 0.0925 0.3829 0.5879
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.022 0.0332
Echinococcus granulosus alpha tubulin 0.1171 0.4862 0.7468
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0049 0.0146 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.1039 0.1591
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0241 0.0364
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0036 0.0053
Loa Loa (eye worm) Smad1 0.0024 0.0043 0.0063
Loa Loa (eye worm) beta-tubulin 0.1563 0.6509 1
Brugia malayi hypothetical protein 0.0162 0.0624 0.0956
Loa Loa (eye worm) tubulin alpha chain 0.1171 0.4862 0.7469
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0159 0.0155
Trichomonas vaginalis tubulin beta chain, putative 0.1171 0.4862 0.7468
Onchocerca volvulus 0.0478 0.1952 1
Leishmania major beta tubulin 0.1563 0.6509 1
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0396 0.1605 0.2461
Brugia malayi intermediate filament protein 0.0027 0.0054 0.008
Echinococcus granulosus fibroblast growth factor receptor 4 0.0104 0.038 0.0578
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0096 0.0145
Schistosoma mansoni tyrosine kinase 0.0212 0.083 0.1273
Schistosoma mansoni nuclear receptor 0.0052 0.0159 0.0241
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0004 0.0003
Loa Loa (eye worm) TK protein kinase 0.0035 0.009 0.0136
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0061 0.0091
Loa Loa (eye worm) hypothetical protein 0.0058 0.0185 0.0282
Plasmodium vivax vivapain-2 0.0017 0.0011 0.0017
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.018 0.027
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0011 0.0011
Giardia lamblia Epsilon tubulin 0.0448 0.1826 0.2794
Schistosoma mansoni smad1 5 8 and 0.0024 0.0043 0.0062
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0024 0.0044 0.0052
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.001 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-41 0.011 0.0403 0.0616
Schistosoma mansoni alpha tubulin 0.1171 0.4862 0.7468
Brugia malayi hypothetical protein 0.0037 0.0096 0.0146
Echinococcus multilocularis musashi 0.0027 0.0054 0.005
Brugia malayi Kelch motif family protein 0.0047 0.014 0.0213
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0096 0.0141
Echinococcus multilocularis tumor protein p63 0.0336 0.1354 0.135
Schistosoma mansoni tubulin subunit alpha 0.1171 0.4862 0.7468
Mycobacterium ulcerans beta-lactamase 0.0145 0.055 0.3383
Trypanosoma cruzi tubulin delta chain 0.0725 0.2988 0.4588
Brugia malayi MH1 domain containing protein 0.0024 0.0043 0.0063
Entamoeba histolytica tubulin gamma chain 0.0925 0.3829 0.5882
Echinococcus granulosus neuroglian 0.0024 0.0041 0.0057
Brugia malayi hypothetical protein 0.0052 0.0159 0.0242
Leishmania major trypanothione reductase 0.0047 0.0139 0.0207
Brugia malayi glutaminase DH11.1 0.029 0.116 0.178
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0038 0.01 0.0152
Leishmania major beta tubulin 0.1563 0.6509 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 126 nM In vitro concentration required to inhibit peak currents in cerebral cortical neurones of rat ChEMBL. 15658856
Ki (binding) = 250 nM Displacement of [3H]-muscimol from rat brain gamma-aminobutyric-acid GABA-A receptor ChEMBL. 15658856
Ki (binding) = 250 nM Displacement of [3H]-muscimol from rat brain gamma-aminobutyric-acid GABA-A receptor ChEMBL. 15658856

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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