Detailed information for compound 43092

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 349.491 | Formula: C18H27N3O2S
  • H donors: 0 H acceptors: 2 LogP: 2.07 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(S(=O)(=O)N1CCCC1)[C@@H]1CCN2[C@@H](C1)c1ccccc1CC2
  • InChi: 1S/C18H27N3O2S/c1-19(24(22,23)21-10-4-5-11-21)16-9-13-20-12-8-15-6-2-3-7-17(15)18(20)14-16/h2-3,6-7,16,18H,4-5,8-14H2,1H3/t16-,18+/m1/s1
  • InChiKey: PDYPHDGHRXHNNJ-AEFFLSMTSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Adrenergic receptor alpha-2 Starlite/ChEMBL References
Rattus norvegicus Adrenergic receptor alpha-1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis fmrfamide receptor Adrenergic receptor alpha-2   450 aa 366 aa 19.9 %
Echinococcus multilocularis neuropeptides capa receptor Adrenergic receptor alpha-2   450 aa 486 aa 20.6 %
Schistosoma mansoni biogenic amine (5HT) receptor Adrenergic receptor alpha-2   450 aa 433 aa 27.9 %
Loa Loa (eye worm) TYRA-2 protein Adrenergic receptor alpha-2   450 aa 488 aa 23.8 %
Echinococcus multilocularis alpha 1A adrenergic receptor Adrenergic receptor alpha-2   450 aa 478 aa 20.7 %
Schistosoma mansoni amine GPCR Adrenergic receptor alpha-2   450 aa 439 aa 29.2 %
Echinococcus multilocularis serotonin receptor Adrenergic receptor alpha-2   450 aa 426 aa 31.9 %
Onchocerca volvulus Adrenergic receptor alpha-2   450 aa 467 aa 25.1 %
Echinococcus granulosus alpha 1A adrenergic receptor Adrenergic receptor alpha-2   450 aa 476 aa 21.0 %
Echinococcus granulosus biogenic amine 5HT receptor Adrenergic receptor alpha-2   450 aa 423 aa 31.7 %
Schistosoma japonicum ko:K04207 neuropeptide Y receptor Y5, putative Adrenergic receptor alpha-2   450 aa 378 aa 20.9 %
Onchocerca volvulus Adrenergic receptor alpha-2   450 aa 420 aa 19.8 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Adrenergic receptor alpha-2   450 aa 473 aa 24.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tyrosine protein kinase Fyn 0.0103 0.0116 0.0115
Toxoplasma gondii aminopeptidase N, putative 0.0049 0.0044 0.0904
Echinococcus granulosus hematopoietic lineage cell specific protein 0.002 0.0005 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0018
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0017 0.0016
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0033 0.0022 0.0453
Leishmania major proteasome beta-1 subunit, putative 0.0022 0.0006 0.0026
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0033 0.0022 0.0586
Schistosoma mansoni adenoreceptor 0.0136 0.0161 0.0489
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0022 0.0006 0.0019
Brugia malayi CXXC zinc finger family protein 0.003 0.0017 0.0031
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0118 0.0136 0.3635
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0022 0.0006 0.0097
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0022 0.0006 0.0097
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.0002 0.0005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0002 0.0015
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0118 0.0136 0.1162
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Brugia malayi Kringle domain containing protein 0.0036 0.0025 0.0048
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0136 0.0161 0.0159
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Brugia malayi G protein-coupled receptor F59B2.13 0.0136 0.0161 0.0318
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0155 0.0186 0.0369
Plasmodium vivax aspartyl proteinase, putative 0.0295 0.0375 1
Loa Loa (eye worm) hypothetical protein 0.0285 0.0361 0.0717
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0092 0.0101 0.0306
Schistosoma mansoni growth factor receptor-bound protein 0.0036 0.0026 0.0078
Loa Loa (eye worm) CHromoDomain protein family member 0.0035 0.0024 0.0046
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0004
Echinococcus granulosus tyrosine protein kinase Fyn 0.0103 0.0116 0.0115
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.012 0.0139 0.0275
Entamoeba histolytica BAR/SH3 domain containing protein 0.002 0.0005 0.0007
Trypanosoma cruzi aminopeptidase, putative 0.0049 0.0044 0.0173
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0161 0.0489
Giardia lamblia Proteasome subunit beta type 1 0.0118 0.0136 0.1152
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0022 0.0006 0.0026
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0136 0.0161 0.0489
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0032 0.002 0.0299
Schistosoma mansoni neuropeptide receptor 0.0136 0.0161 0.0489
Plasmodium falciparum plasmepsin II 0.0295 0.0375 1
Echinococcus multilocularis neuropeptide Y receptor 0.0136 0.0161 0.0159
Schistosoma mansoni amine GPCR 0.0136 0.0161 0.0489
Loa Loa (eye worm) hypothetical protein 0.0778 0.1026 0.2044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0091 0.01 0.0197
Echinococcus granulosus biogenic amine 5HT receptor 0.0136 0.0161 0.0159
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0042 0.0126
Brugia malayi AKH receptor 0.0136 0.0161 0.0318
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0022 0.0006 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0018
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0017 0.0031
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0051 0.0046 0.0183
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0199 0.0245 0.0487
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0033 0.0022 0.0067
Entamoeba histolytica tubulin family protein 0.0025 0.0011 0.0303
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0022 0.0006 0.0026
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0011 0.001
Plasmodium falciparum plasmepsin X 0.0147 0.0175 0.468
Schistosoma mansoni hypothetical protein 0.0063 0.0062 0.0188
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0039
Onchocerca volvulus 0.0477 0.0621 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0034 0.0066
Loa Loa (eye worm) hypothetical protein 0.0136 0.016 0.0317
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.002 0.0005 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0136 0.0161 0.0159
Echinococcus multilocularis proteasome (prosome, macropain) 0.0155 0.0186 0.0185
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0029 0.0016 0.0015
Onchocerca volvulus 0.0037 0.0027 0.0409
Loa Loa (eye worm) peptidase family M13 containing protein 0.0278 0.0352 0.0699
Brugia malayi Protein kinase domain containing protein 0.002 0.0004 0.0006
Echinococcus granulosus tyrosine protein kinase HCK 0.0067 0.0068 0.0066
Schistosoma mansoni cpg binding protein 0.0031 0.0019 0.0058
Leishmania major hypothetical protein, conserved 0.002 0.0005 0.0018
Brugia malayi Serotonin receptor 0.0136 0.0161 0.0318
Loa Loa (eye worm) TK protein kinase 0.0083 0.0089 0.0174
Giardia lamblia Proteasome subunit beta type 3 0.0022 0.0006 0.0044
Brugia malayi hypothetical protein 0.0049 0.0044 0.0085
Loa Loa (eye worm) tubulin beta-1 chain 0.0025 0.0011 0.0019
Echinococcus multilocularis neuropeptide s receptor 0.0136 0.0161 0.0159
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0227 0.0283 0.086
Trichomonas vaginalis hypothetical protein 0.0033 0.0022 0.0187
Loa Loa (eye worm) hypothetical protein 0.0285 0.0361 0.0717
Schistosoma mansoni caspase-3 (C14 family) 0.0018 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Echinococcus granulosus peroxidasin 0.0139 0.0164 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Brugia malayi Tyrosine-protein kinase abl-1 0.0041 0.0032 0.0061
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0022 0.0006 0.0005
Echinococcus multilocularis transfer RNA-Ala 0.002 0.0005 0.0003
Brugia malayi Protein kinase domain containing protein 0.002 0.0004 0.0006
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0022 0.0006 0.0026
Echinococcus multilocularis endophilin A3 0.002 0.0005 0.0003
Schistosoma mansoni chromobox protein 0.0569 0.0745 0.2267
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.3737 0.5015 1
Echinococcus multilocularis proteasome subunit beta type 6 0.0022 0.0006 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0044 0.0133
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0022 0.0006 0.0172
Echinococcus granulosus tm gpcr rhodopsin 0.0136 0.0161 0.0159
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.1889 0.2524 1
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0022 0.0006 0.0055
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0022 0.0006 0.0133
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0886 0.1172 1
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus beta tubulin 0.0025 0.0011 0.001
Echinococcus multilocularis chromobox protein 2 0.0569 0.0745 0.0743
Schistosoma mansoni ets-related 0.023 0.0287 0.0873
Brugia malayi aspartic protease BmAsp-1, identical 0.0147 0.0175 0.0347
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0136 0.0161 0.0318
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0136 0.0161 0.0489
Plasmodium falciparum plasmepsin VIII, putative 0.0147 0.0175 0.468
Echinococcus granulosus proteasome prosome macropain 0.0155 0.0186 0.0185
Entamoeba histolytica hypothetical protein 0.002 0.0005 0.0007
Brugia malayi Variant SH3 domain containing protein 0.002 0.0005 0.0006
Echinococcus granulosus g protein coupled receptor 0.0136 0.0161 0.0159
Echinococcus granulosus NCK adaptor protein 0.0036 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Onchocerca volvulus 0.003 0.0017 0.0254
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.1889 0.2524 0.7687
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0044 0.0042
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0022 0.0006 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0011 0.0032
Brugia malayi Angiotensin-converting enzyme family protein 0.3737 0.5015 1
Onchocerca volvulus Peroxidase homolog 0.0139 0.0164 0.2624
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0227 0.0283 0.0281
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0002 0.0007
Schistosoma mansoni tubulin subunit beta 0.0025 0.0011 0.0033
Echinococcus multilocularis neuropeptides capa receptor 0.0136 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus hypothetical protein 0.0136 0.0161 0.0159
Trypanosoma brucei Aminopeptidase M1, putative 0.0141 0.0167 0.066
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0044 0.0042
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0002 0.0015
Brugia malayi Protein cec-1. 0.0033 0.0022 0.0041
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0022 0.0006 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0022 0.0006 0.0097
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0022 0.0006 0.0055
Brugia malayi Peptidase family M1 containing protein 0.0049 0.0044 0.0085
Brugia malayi Variant SH3 domain containing protein 0.002 0.0005 0.0006
Echinococcus multilocularis GA binding protein alpha chain 0.0076 0.0079 0.0078
Echinococcus granulosus endophilin A3 0.002 0.0005 0.0003
Toxoplasma gondii aminopeptidase n, putative 0.0049 0.0044 0.0904
Toxoplasma gondii proteasome beta subunit 0.0022 0.0006 0.0133
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0056 0.0109
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0136 0.0161 0.0489
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Schistosoma mansoni tubulin subunit beta 0.0025 0.0011 0.0033
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0136 0.0161 0.0159
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0011 0.001
Schistosoma mansoni ap endonuclease 0.0059 0.0056 0.0171
Onchocerca volvulus 0.0268 0.0339 0.5444
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0042 0.008
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Brugia malayi Ets-domain containing protein 0.0076 0.0079 0.0155
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0022 0.0006 0.0097
Echinococcus multilocularis g protein coupled receptor 0.0136 0.0161 0.0159
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0022 0.0006 0.0026
Onchocerca volvulus 0.0136 0.0161 0.2574
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0748 0.0985 0.1963
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0136 0.0161 0.0159
Brugia malayi RE15519p 0.0136 0.0161 0.0318
Brugia malayi Variant SH3 domain containing protein 0.002 0.0005 0.0006
Onchocerca volvulus Peroxidasin homolog 0.0139 0.0164 0.2624
Echinococcus granulosus tubulin beta 1 chain 0.0025 0.0011 0.001
Echinococcus multilocularis allatostatin A receptor 0.0136 0.0161 0.0159
Plasmodium vivax aspartyl protease, putative 0.0147 0.0175 0.468
Onchocerca volvulus 0.0049 0.0044 0.0686
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0118 0.0136 0.054
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0136 0.0161 0.0159
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0017 0.0352
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Schistosoma mansoni tyrosine kinase 0.0041 0.0032 0.0096
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0022 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0022 0.0006 0.0019
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0078 0.0083 0.0082
Trypanosoma cruzi aminopeptidase, putative 0.0141 0.0167 0.066
Schistosoma mansoni growth factor receptor-bound protein 0.0036 0.0026 0.0078
Echinococcus multilocularis serotonin receptor 0.0136 0.0161 0.0159
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0103 0.0116 0.0115
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.7435 1 1
Schistosoma mansoni cpg binding protein 0.003 0.0017 0.0052
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.002 0.0005 0.0003
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0056 0.2441
Schistosoma mansoni opsin-like receptor 0.0136 0.0161 0.0489
Brugia malayi hypothetical protein 0.0141 0.0167 0.033
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Onchocerca volvulus 0.002 0.0005 0.0052
Onchocerca volvulus 0.0147 0.0175 0.2809
Toxoplasma gondii aspartyl protease ASP3 0.0147 0.0175 0.3621
Brugia malayi SH3 domain containing protein 0.002 0.0005 0.0006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0199 0.0245 0.0487
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0886 0.1172 1
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0136 0.0161 0.0489
Loa Loa (eye worm) TYRA-2 protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0022 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0041
Echinococcus multilocularis peregrin 0.003 0.0017 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0136 0.0161 0.0159
Mycobacterium ulcerans aminopeptidase N PepN 0.0049 0.0044 0.0153
Echinococcus granulosus epidermal growth factor receptor kinase 0.002 0.0005 0.0003
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0022 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0039
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0295 0.0375 0.1141
Schistosoma mansoni growth hormone secretagogue receptor 0.0136 0.0161 0.0489
Loa Loa (eye worm) proteasome subunit beta type 1 0.0118 0.0136 0.0269
Brugia malayi Blistered cuticle protein 3 0.0139 0.0164 0.0324
Loa Loa (eye worm) proteasome subunit beta type 3 0.0022 0.0006 0.001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0147 0.0175 0.0534
Brugia malayi Heterochromatin protein 1 0.0033 0.0022 0.0041
Schistosoma mansoni run and tbc1 domain containing 0.002 0.0005 0.0014
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0376 0.0484 0.1474
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0022 0.0006 0.0026
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0035 0.0024 0.0023
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0022 0.0006 0.0055
Loa Loa (eye worm) guanylate kinase 0.0055 0.0052 0.0101
Echinococcus granulosus fmrfamide receptor 0.0136 0.0161 0.0159
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0022 0.0006 0.0005
Echinococcus granulosus dro:myosuppressin receptor 0.0136 0.0161 0.0159
Schistosoma mansoni eps8-related protein 0.002 0.0005 0.0014
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0022 0.0006 0.0026
Plasmodium vivax proteasome subunit beta type-5, putative 0.0155 0.0186 0.4966
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.019 0.0233 0.0709
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0103 0.0116 0.0115
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0049 0.0044 0.0373
Trypanosoma brucei C-8 sterol isomerase, putative 0.0748 0.0985 0.3904
Brugia malayi Tachykinin-like peptides receptor 99D 0.0136 0.0161 0.0318
Plasmodium vivax proteasome subunit beta type-7, putative 0.0022 0.0006 0.0172
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0022 0.0006 0.0019
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0022 0.0006 0.0133
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0002 0.0015
Mycobacterium tuberculosis Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) 0.006 0.0058 0.1103
Loa Loa (eye worm) tubulin beta-2A chain 0.0025 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Toxoplasma gondii beta tubulin 0.0025 0.0011 0.0223
Brugia malayi Variant SH3 domain containing protein 0.0036 0.0026 0.0049
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0002 0.0002
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0033 0.0022 0.0453
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Plasmodium vivax plasmepsin IV, putative 0.0295 0.0375 1
Trypanosoma brucei beta tubulin 0.0025 0.0011 0.0043
Echinococcus granulosus tyrosine protein kinase Src64B 0.0103 0.0116 0.0115
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0141 0.0167 0.0165
Schistosoma mansoni biogenic amine receptor 0.0136 0.0161 0.0489
Toxoplasma gondii aspartyl protease 0.0147 0.0175 0.3621
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0022 0.0006 0.0026
Echinococcus granulosus cpg binding protein 0.0031 0.0019 0.0018
Onchocerca volvulus 0.0139 0.0164 0.2624
Echinococcus multilocularis proteasome subunit alpha type 6 0.0022 0.0006 0.0005
Loa Loa (eye worm) variant SH3 domain-containing protein 0.002 0.0005 0.0006
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0022 0.0006 0.001
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0022 0.0586
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0022 0.0006 0.0097
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0056 0.2134
Schistosoma mansoni tyrosine kinase 0.0041 0.0032 0.0096
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0022 0.0006 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0022 0.0006 0.0019
Schistosoma mansoni peroxidasin 0.0139 0.0164 0.0499
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0022 0.0006 0.0026
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0022 0.0333
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0017 0.0352
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0886 0.1172 1
Toxoplasma gondii beta-1 tubulin, putative 0.0025 0.0011 0.0223
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0136 0.0161 0.0489
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0141 0.0167 0.0507
Schistosoma mansoni replication factor A 1 rfa1 0.0035 0.0025 0.0075
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0136 0.0161 0.0159
Brugia malayi proteasome subunit alpha type 1 0.0022 0.0006 0.001
Schistosoma mansoni neuropeptide receptor 0.0136 0.0161 0.0489
Brugia malayi hypothetical protein 0.0177 0.0216 0.0429
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.0062 0.0061
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0136 0.0161 0.0318
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0295 0.0375 0.0745
Echinococcus multilocularis expressed protein 0.002 0.0005 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Mycobacterium ulcerans proteasome PrcB 0.0155 0.0186 0.0718
Echinococcus multilocularis aminopeptidase N 0.0477 0.0621 0.062
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.1889 0.2524 0.2523
Loa Loa (eye worm) G-protein coupled receptor 0.0136 0.0161 0.0318
Schistosoma mansoni nck2/grb4 0.0036 0.0026 0.0078
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0044 0.0085
Schistosoma mansoni sorting nexin 0.002 0.0005 0.0014
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0022 0.0006 0.0055
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0059 0.0057 0.0111
Brugia malayi proteasome subunit alpha type 4 0.0022 0.0006 0.001
Echinococcus multilocularis beta tubulin 0.0025 0.0011 0.001
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0044 0.0173
Echinococcus granulosus neuropeptide Y receptor 0.0136 0.0161 0.0159
Echinococcus multilocularis dnaJ subfamily B 0.0421 0.0545 0.0544
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Schistosoma mansoni neuropeptide F-like receptor 0.0136 0.0161 0.0489
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0141 0.0167 0.0165
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0005 0.0007
Schistosoma mansoni patched 1 0.0778 0.1026 0.3123
Brugia malayi larval opioid receptor 0.0136 0.0161 0.0318
Brugia malayi Peripheral plasma membrane protein CASK 0.0036 0.0026 0.0049
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0022 0.0333
Loa Loa (eye worm) animal heme peroxidase 0.0139 0.0164 0.0324
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0022 0.0006 0.0055
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0022 0.0006 0.0026
Onchocerca volvulus 0.002 0.0005 0.0052
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Schistosoma mansoni tubulin subunit beta 0.0025 0.0011 0.0033
Onchocerca volvulus 0.0147 0.0175 0.2809
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0023 0.0069
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0295 0.0375 0.3196
Brugia malayi Proteasome subunit alpha type 1 0.0022 0.0006 0.001
Loa Loa (eye worm) tubulin beta chain 0.0025 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0285 0.0361 0.0717
Echinococcus multilocularis caspase 2 0.0061 0.0059 0.0058
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0022 0.0006 0.0055
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0141 0.0167 0.0165
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0042 0.004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0042 0.008
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0022 0.0006 0.0097
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Schistosoma mansoni dynamin-associated protein 0.002 0.0005 0.0014
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Loa Loa (eye worm) hypothetical protein 0.0285 0.0361 0.0717
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0022 0.0006 0.001
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0022 0.0006 0.0026
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0011 0.001
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Plasmodium falciparum phd finger protein, putative 0.003 0.0017 0.0455
Brugia malayi Peptidase family M1 containing protein 0.0141 0.0167 0.033
Giardia lamblia Beta tubulin 0.0025 0.0011 0.0081
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0136 0.0161 0.0159
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0022 0.0006 0.0019
Brugia malayi Bromodomain containing protein 0.003 0.0017 0.0031
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0022 0.0187
Trypanosoma brucei conserved protein 0.002 0.0005 0.0018
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0118 0.0136 0.0414
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0147 0.0175 0.0534
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0136 0.0161 0.0489
Brugia malayi Animal haem peroxidase family protein 0.0139 0.0164 0.0324
Schistosoma mansoni neuropeptide receptor 0.0136 0.0161 0.0489
Echinococcus multilocularis fmrfamide receptor 0.0136 0.0161 0.0159
Onchocerca volvulus 0.0136 0.0161 0.2574
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0022 0.0006 0.0026
Echinococcus granulosus tyrosine protein kinase Src42A 0.0103 0.0116 0.0115
Brugia malayi CHD4 protein 0.0035 0.0024 0.0046
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0022 0.0187
Echinococcus granulosus Niemann Pick C1 protein 0.0778 0.1026 0.1025
Schistosoma mansoni hypothetical protein 0.0268 0.0339 0.1031
Trypanosoma brucei ribonucleoside-diphosphate reductase large chain 0.0198 0.0244 0.0966
Plasmodium falciparum plasmepsin V 0.0147 0.0175 0.468
Loa Loa (eye worm) hypothetical protein 0.1889 0.2524 0.5032
Echinococcus multilocularis tyrosine protein kinase Abl 0.0041 0.0032 0.003
Echinococcus granulosus neuropeptides capa receptor 0.0136 0.0161 0.0159
Echinococcus multilocularis sterol regulatory element binding protein 0.0778 0.1026 0.1025
Loa Loa (eye worm) hypothetical protein 0.0376 0.0484 0.0963
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0083 0.0089 0.0087
Loa Loa (eye worm) hypothetical protein 0.003 0.0017 0.0031
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0022 0.0006 0.0005
Mycobacterium tuberculosis Probable transcriptional regulatory protein NrdR 0.0031 0.0019 0.0288
Loa Loa (eye worm) BEN-1 protein 0.0025 0.0011 0.0019
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0136 0.0161 0.0318
Schistosoma mansoni dreadlocks/dock 0.002 0.0005 0.0014
Plasmodium falciparum tubulin beta chain 0.0025 0.0011 0.0288
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0022 0.0006 0.001
Schistosoma mansoni hypothetical protein 0.0136 0.0161 0.0489
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0161 0.0489
Loa Loa (eye worm) animal heme peroxidase 0.0139 0.0164 0.0324
Schistosoma mansoni hypothetical protein 0.0177 0.0216 0.0658
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0022 0.0006 0.001
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0136 0.0161 0.0159
Plasmodium vivax proteasome subunit beta type-1, putative 0.0118 0.0136 0.3635
Echinococcus granulosus inhibitor of apoptosis protein 0.0268 0.0339 0.0337
Brugia malayi Ets-domain containing protein 0.0076 0.0079 0.0155
Brugia malayi Melatonin receptor type 1A 0.0136 0.0161 0.0318
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0022 0.0006 0.001
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0022 0.0006 0.001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0147 0.0175 0.0534
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.0062 0.0061
Schistosoma mansoni tubulin subunit beta 0.0025 0.0011 0.0033
Loa Loa (eye worm) peptidase family M13 containing protein 0.0278 0.0352 0.0699
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0022 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Schistosoma mansoni adapter molecule crk 0.0036 0.0026 0.0078
Brugia malayi CHE-14 protein 0.0778 0.1026 0.2044
Echinococcus granulosus Proteasome subunit alpha beta 0.0022 0.0006 0.0005
Schistosoma mansoni tyrosine kinase 0.002 0.0004 0.0013
Brugia malayi peptidase family M13 containing protein 0.0092 0.0101 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0027 0.0229
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0041
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0041 0.0032 0.003
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0022 0.0006 0.0172
Loa Loa (eye worm) protein-tyrosine kinase 0.002 0.0005 0.0006
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0022 0.0006 0.0097
Schistosoma mansoni neuropeptide F-like receptor 0.0136 0.0161 0.0489
Echinococcus multilocularis neuropeptide receptor A26 0.0136 0.0161 0.0159
Echinococcus granulosus Spectrin alpha actinin 0.002 0.0005 0.0003
Onchocerca volvulus 0.0033 0.0022 0.0333
Echinococcus granulosus Chromobox protein 3 0.0033 0.0022 0.0021
Brugia malayi TATA binding protein associated factor 0.0049 0.0044 0.0085
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0748 0.0985 0.3904
Loa Loa (eye worm) hypothetical protein 0.0186 0.0228 0.0453
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0136 0.0161 0.0318
Giardia lamblia Beta tubulin 0.0025 0.0011 0.0081
Trichomonas vaginalis glutaminase, putative 0.0272 0.0343 0.293
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0039
Brugia malayi SH2 domain containing protein 0.002 0.0004 0.0006
Loa Loa (eye worm) p53BP2 0.002 0.0005 0.0006
Brugia malayi Myosin tail family protein 0.002 0.0005 0.0006
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0141 0.0167 0.066
Echinococcus granulosus neuropeptide receptor 0.0136 0.0161 0.0159
Brugia malayi Eukaryotic aspartyl protease family protein 0.0147 0.0175 0.0347
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0022 0.0006 0.0019
Echinococcus granulosus tyrosine protein kinase ABL1 0.002 0.0004 0.0003
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0136 0.0161 0.0159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0161 0.0489
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Schistosoma mansoni chromobox protein 0.0033 0.0022 0.0067
Loa Loa (eye worm) hypothetical protein 0.0555 0.0725 0.1443
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0017 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0031 0.0264
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0022 0.0006 0.0019
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0022 0.0006 0.0026
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0022 0.0187
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0049 0.0044 0.1168
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0022 0.0006 0.0005
Loa Loa (eye worm) neuropeptide F receptor 0.0136 0.0161 0.0318
Plasmodium vivax hypothetical protein, conserved 0.003 0.0017 0.0455
Trichomonas vaginalis tubulin epsilon chain, putative 0.0025 0.0011 0.0092
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0042 0.004
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0022 0.0006 0.0019
Schistosoma mansoni cell polarity protein 0.0018 0.0001 0.0004
Brugia malayi protein-tyrosine kinase 0.0083 0.0089 0.0174
Echinococcus multilocularis sex peptide receptor 0.0136 0.0161 0.0159
Loa Loa (eye worm) SRC-1 0.0103 0.0116 0.0229
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0155 0.0186 0.8572
Brugia malayi SRC-1 0.0103 0.0116 0.0229
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0049 0.0044 0.0173
Plasmodium falciparum proteasome subunit beta type-5 0.0155 0.0186 0.4966
Entamoeba histolytica unconventional myosin IB 0.002 0.0005 0.0007
Brugia malayi hypothetical protein 0.002 0.0004 0.0006
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0036 0.0026 0.0049
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0025 0.0011 0.001
Trypanosoma brucei beta tubulin 0.0025 0.0011 0.0043
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0002 0.0015
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Brugia malayi Spectrin alpha chain 0.002 0.0005 0.0006
Entamoeba histolytica hypothetical protein 0.0177 0.0216 1
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0198 0.0244 0.0966
Brugia malayi Proteasome A-type and B-type family protein 0.0022 0.0006 0.001
Plasmodium falciparum ribonucleoside-diphosphate reductase large subunit, putative 0.0198 0.0244 0.6511
Schistosoma mansoni tyrosine kinase 0.002 0.0004 0.0013
Giardia lamblia 20S proteasome alpha subunit 2 0.0022 0.0006 0.0044
Loa Loa (eye worm) peptidase family M1 containing protein 0.0386 0.0498 0.0991
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0022 0.0007 0.0126
Entamoeba histolytica hypothetical protein 0.0177 0.0216 1
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Brugia malayi Dopamine receptor protein 2 0.0136 0.0161 0.0318
Toxoplasma gondii proteasome subunit 0.0022 0.0006 0.0133
Echinococcus granulosus sterol regulatory element binding protein 0.0778 0.1026 0.1025
Echinococcus granulosus tyrosine protein kinase shark 0.002 0.0004 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0136 0.0161 0.0159
Brugia malayi hypothetical protein 0.0042 0.0034 0.0066
Schistosoma mansoni biogenic amine (5HT) receptor 0.0136 0.0161 0.0489
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0042 0.004
Plasmodium vivax proteasome subunit beta type-2, putative 0.0022 0.0006 0.0172
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0049 0.0044 0.0173
Onchocerca volvulus 0.0136 0.0161 0.2574
Echinococcus granulosus disks large 3 0.0048 0.0042 0.0041
Leishmania major proteasome beta 2 subunit, putative 0.0022 0.0006 0.0026
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0062 0.0121
Brugia malayi Src substrate cortactin 0.002 0.0005 0.0006
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0141 0.0167 0.0165
Brugia malayi PHD-finger family protein 0.003 0.0017 0.0031
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0136 0.0161 0.0489
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0035 0.0025 0.0212
Echinococcus granulosus tyrosine protein kinase Fyn 0.0103 0.0116 0.0115
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0141 0.0167 0.0165
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0136 0.0161 0.0159
Trypanosoma brucei Metacaspase-4 0.0018 0.0002 0.0007
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0022 0.0006 0.0172
Loa Loa (eye worm) hypothetical protein 0.0049 0.0044 0.0085
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Echinococcus granulosus nostrin 0.002 0.0005 0.0003
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.002 0.0005 0.0003
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0022 0.0006 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0002 0.0015
Schistosoma mansoni C-fyn 0.002 0.0005 0.0014
Brugia malayi Proteasome A-type and B-type family protein 0.0022 0.0006 0.001
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0044 0.0042
Plasmodium vivax ribonucleoside-diphosphate reductase large chain, putative 0.0198 0.0244 0.6511
Brugia malayi protein-tyrosine kinase 0.002 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.002 0.0005 0.0014
Schistosoma mansoni hypothetical protein 0.0421 0.0545 0.1659
Echinococcus granulosus g protein coupled receptor 0.0136 0.0161 0.0159
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0141 0.0167 0.066
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0062 0.0121
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit alpha 0.0167 0.0202 0.0782
Mycobacterium leprae conserved hypothetical protein 0.0031 0.0019 0.0263
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0152 0.0182 0.0553
Brugia malayi Pepsin A precursor 0.0147 0.0175 0.0347
Loa Loa (eye worm) hypothetical protein 0.0036 0.0026 0.0049
Schistosoma mansoni amine GPCR 0.0136 0.0161 0.0489
Leishmania major proteasome alpha 1 subunit, putative 0.0022 0.0006 0.0026
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0044 0.0042
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0056 0.0479
Leishmania major proteasome alpha 7 subunit, putative 0.0022 0.0006 0.0026
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0022 0.0006 0.0172
Echinococcus multilocularis Chromo domain 0.0033 0.0022 0.0021
Loa Loa (eye worm) TK/ABL protein kinase 0.002 0.0004 0.0006
Mycobacterium ulcerans transcriptional regulator NrdR 0.0031 0.0019 0.0055
Trypanosoma cruzi 20S proteasome subunit 0.0022 0.0006 0.0026
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0076 0.0079 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0002 0.0015
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0044 0.0173
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0136 0.0161 0.0159
Brugia malayi proteasome subunit alpha type 2 0.0022 0.0006 0.001
Echinococcus multilocularis G protein coupled receptor 139 0.0136 0.0161 0.0159
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0062 0.0121
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0018 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0147 0.0175 0.0347
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.002 0.0004 0.0003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0028 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0041
Echinococcus granulosus aminopeptidase N 0.0477 0.0621 0.062
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0136 0.0161 0.0489
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0147 0.0175 0.0534
Brugia malayi proteasome subunit alpha type 6 0.0022 0.0006 0.001
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0035 0.0025 0.0212
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0056 0.0222
Brugia malayi hypothetical protein 0.0147 0.0175 0.0347
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0017 0.0052
Loa Loa (eye worm) blistered cuticle protein 3 0.0139 0.0164 0.0324
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0031 0.0264
Loa Loa (eye worm) hypothetical protein 0.0036 0.0025 0.0048
Onchocerca volvulus 0.0136 0.0161 0.2574
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0022 0.0828
Schistosoma mansoni slit 0.0018 0.0001 0.0004
Trypanosoma brucei proteasome beta 6 subunit 0.0118 0.0136 0.054
Echinococcus granulosus tissue type plasminogen activator 0.0036 0.0025 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit alpha 0.0198 0.0244 1
Schistosoma mansoni sorbin 0.002 0.0005 0.0014
Giardia lamblia 20S proteasome alpha subunit 6 0.0022 0.0006 0.0044
Schistosoma mansoni transcription factor LCR-F1 0.0177 0.0216 0.0658
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0022 0.0006 0.0026
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0022 0.0006 0.0172
Plasmodium vivax tubulin beta chain, putative 0.0025 0.0011 0.0288
Echinococcus multilocularis neuropeptide Y receptor 0.0136 0.0161 0.0159
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0022 0.0006 0.0097
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0022 0.0006 0.0026
Echinococcus granulosus Proteasome subunit alpha type 7 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0041
Schistosoma mansoni peptidylglycine monooxygenase 0.012 0.0139 0.0424
Brugia malayi Protein kinase domain containing protein 0.004 0.0031 0.006
Loa Loa (eye worm) TK/ROR protein kinase 0.004 0.0031 0.006
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0022 0.0006 0.0055
Echinococcus multilocularis epidermal growth factor receptor kinase 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0748 0.0985 0.1963
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0227 0.0283 0.0281
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0033 0.0022 0.0041
Loa Loa (eye worm) hypothetical protein 0.0278 0.0352 0.0699
Echinococcus multilocularis chromobox protein 1 0.0033 0.0022 0.0021
Echinococcus multilocularis intersectin 2 0.002 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Loa Loa (eye worm) hypothetical protein 0.0051 0.0046 0.0088
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus somatostatin receptor 0.0136 0.0161 0.0159
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0136 0.0161 0.0159
Schistosoma mansoni ap endonuclease 0.0059 0.0056 0.0171
Echinococcus multilocularis tubulin beta 1 chain 0.0025 0.0011 0.001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0002 0.0015
Echinococcus multilocularis ribonucleoside diphosphate reductase large 0.0198 0.0244 0.0243
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.002 0.0005 0.0014
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0022 0.0006 0.0019
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0005 0.0007
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0227 0.0283 0.0561
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Loa Loa (eye worm) melatonin receptor type 1A 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0061 0.0059 0.0115
Brugia malayi Proteasome subunit alpha type 7-1 0.0022 0.0006 0.001
Schistosoma mansoni opsin-like receptor 0.0136 0.0161 0.0489
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0081 0.0246
Entamoeba histolytica hypothetical protein 0.0033 0.0022 0.0828
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0022 0.0187
Schistosoma mansoni hypothetical protein 0.0033 0.0022 0.0067
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0136 0.0161 0.0318
Brugia malayi GnHR receptor homolog 0.0136 0.0161 0.0318
Onchocerca volvulus 0.0136 0.0161 0.2574
Leishmania major metacaspase, putative 0.0018 0.0002 0.0007
Trypanosoma cruzi metacaspase, putative 0.0018 0.0002 0.0007
Schistosoma mansoni laminin gamma-3 chain 0.0018 0.0001 0.0004
Trypanosoma brucei aminopeptidase, putative 0.0049 0.0044 0.0173
Loa Loa (eye worm) hypothetical protein 0.0376 0.0484 0.0963
Trichomonas vaginalis p67phox protein, putative 0.002 0.0005 0.0039
Brugia malayi Valyl-tRNA synthetase 0.0033 0.0022 0.0041
Toxoplasma gondii proteasome subunit beta type, putative 0.0155 0.0186 0.3842
Schistosoma mansoni slit-robo rho gtpase activating protein 0.002 0.0005 0.0014
Onchocerca volvulus 0.002 0.0004 0.005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0022 0.0187
Echinococcus granulosus tubulin beta 4A class IVa 0.0025 0.0011 0.001
Trichomonas vaginalis tubulin, putative 0.0025 0.0011 0.0092
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0044 0.0173
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0161 0.0489
Echinococcus granulosus neuropeptides capa receptor 0.0136 0.0161 0.0159
Entamoeba histolytica hypothetical protein 0.002 0.0005 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Plasmodium falciparum plasmepsin VI 0.0295 0.0375 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0136 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Echinococcus granulosus GA binding protein alpha chain 0.0076 0.0079 0.0078
Brugia malayi G protein-coupled receptor 0.0136 0.0161 0.0318
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0002 0.0015
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.1889 0.2524 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0002 0.0036
Onchocerca volvulus 0.0136 0.0161 0.2574
Loa Loa (eye worm) hypothetical protein 0.0278 0.0352 0.0699
Toxoplasma gondii aspartyl protease ASP1 0.0295 0.0375 0.7737
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Trypanosoma brucei metacaspase MCA2 0.0018 0.0002 0.0007
Echinococcus multilocularis tubulin subunit beta 0.0025 0.0011 0.001
Schistosoma mansoni hypothetical protein 0.003 0.0017 0.0052
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0022 0.0006 0.0026
Trypanosoma cruzi metacaspase, putative 0.0018 0.0002 0.0007
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0022 0.0006 0.0026
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0118 0.0136 0.6219
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0022 0.0006 0.0055
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0136 0.0161 0.0489
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.1889 0.2524 1
Brugia malayi Dopamine receptor protein 1 0.0136 0.0161 0.0318
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0031 0.0264
Schistosoma mansoni ribonucleoside-diphosphate reductase alpha subunit 0.0198 0.0244 0.0743
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0022 0.0006 0.0026
Echinococcus multilocularis tyrosine protein kinase ABL1 0.002 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Onchocerca volvulus 0.0034 0.0023 0.0347
Entamoeba histolytica hypothetical protein 0.0033 0.0022 0.0828
Loa Loa (eye worm) hypothetical protein 0.0278 0.0352 0.0699
Trichomonas vaginalis tubulin epsilon chain, putative 0.0025 0.0011 0.0092
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0147 0.0175 0.0347
Echinococcus granulosus proteasome subunit beta type 7 0.0022 0.0006 0.0005
Onchocerca volvulus Alhambra homolog 0.003 0.0017 0.0254
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.2453 0.3284 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0078 0.0083 0.0082
Schistosoma mansoni opsin-like receptor 0.0136 0.0161 0.0489
Schistosoma mansoni Nep2 peptidase (M13 family) 0.019 0.0233 0.0709
Toxoplasma gondii exonuclease III APE 0.0059 0.0056 0.1159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0161 0.0489
Brugia malayi latrophilin 2 splice variant baaae 0.0136 0.016 0.0317
Toxoplasma gondii peptidase, T1 family protein 0.0022 0.0006 0.0133
Brugia malayi putative neuropeptide receptor NPR1 0.0136 0.0161 0.0318
Plasmodium vivax proteasome subunit beta type-3, putative 0.0022 0.0006 0.0172
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0022 0.0006 0.0026
Mycobacterium leprae probable zinc metalloprotease 0.0376 0.0484 1
Schistosoma mansoni cathepsin D (A01 family) 0.0672 0.0883 0.2689
Schistosoma mansoni myosin xvIII 0.0136 0.0161 0.0489
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0022 0.0006 0.0005
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0091 0.01 0.0396
Trypanosoma brucei proteasome alpha 7 subunit 0.0022 0.0006 0.0026
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0022 0.0006 0.0026
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.002 0.0005 0.0039
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0042 0.0126
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0022 0.0006 0.0097
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0034 0.0022 0.0192
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0022 0.0006 0.0044
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0031 0.0264
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0002 0.0036
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0022 0.0828
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Onchocerca volvulus 0.0136 0.0161 0.2574
Toxoplasma gondii kringle domain-containing protein 0.0036 0.0025 0.0521
Onchocerca volvulus 0.002 0.0004 0.005
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0091 0.01 0.0099
Entamoeba histolytica hypothetical protein 0.0177 0.0216 1
Plasmodium falciparum plasmepsin III 0.0147 0.0175 0.468
Loa Loa (eye worm) BEN-1 protein 0.0025 0.0011 0.0019
Echinococcus multilocularis beta tubulin 0.0025 0.0011 0.001
Brugia malayi chromobox protein homolog 3 0.0033 0.0022 0.0041
Echinococcus multilocularis c src tyrosine kinase 0.0041 0.0032 0.003
Brugia malayi proteasome subunit beta type 1 0.0118 0.0136 0.0269
Echinococcus granulosus tm gpcr rhodopsin 0.0136 0.0161 0.0159
Entamoeba histolytica hypothetical protein 0.002 0.0005 0.0007
Onchocerca volvulus Putative cortactin 0.002 0.0005 0.0052
Loa Loa (eye worm) beta-tubulin 0.0025 0.0011 0.0019
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0022 0.0006 0.0019
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0022 0.0006 0.0005
Echinococcus granulosus tyrosine kinase 0.0083 0.0089 0.0087
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0022 0.0006 0.0019
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0033 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0285 0.0361 0.0717
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.002 0.0005 0.0003
Echinococcus granulosus Protein patched homolog 1 0.0778 0.1026 0.1025
Schistosoma mansoni hypothetical protein 0.0063 0.0062 0.0188
Echinococcus multilocularis thyroid hormone receptor alpha 0.0134 0.0157 0.0156
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0062 0.0061
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0022 0.0187
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0031 0.0264
Toxoplasma gondii heat shock protein hslv, putative 0.0022 0.0006 0.0133
Onchocerca volvulus 0.002 0.0004 0.005
Echinococcus granulosus growth factor receptor bound protein 2 0.0036 0.0026 0.0025
Schistosoma mansoni neprilysin-2 (M13 family) 0.019 0.0233 0.0709
Entamoeba histolytica hypothetical protein 0.002 0.0005 0.0007
Schistosoma mansoni biogenic amine receptor 0.0136 0.0161 0.0489
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0056 0.0222
Loa Loa (eye worm) hypothetical protein 0.0194 0.0238 0.0473
Schistosoma mansoni neuropeptide receptor 0.0136 0.0161 0.0489
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0024 0.0073
Mycobacterium ulcerans proteasome PrcA 0.0022 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.002 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0126
Schistosoma mansoni tubulin subunit beta 0.0025 0.0011 0.0033
Schistosoma mansoni cpg binding protein 0.0031 0.0019 0.0058
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.1889 0.2524 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0002 0.0036
Loa Loa (eye worm) thyroid receptor interactor 0.002 0.0005 0.0006
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0022 0.0006 0.0026
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0136 0.0161 0.0159
Schistosoma mansoni cathepsin D (A01 family) 0.0672 0.0883 0.2689
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0011 0.001
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0022 0.0006 0.0172
Leishmania major proteasome alpha 1 subunit, putative 0.0022 0.0006 0.0026
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0049 0.0044 0.0042
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) 0.0167 0.0202 0.4095
Brugia malayi Dopamine receptor 0.0136 0.0161 0.0318
Brugia malayi hypothetical protein 0.0139 0.0164 0.0324
Loa Loa (eye worm) heterochromatin protein 1 0.0033 0.0022 0.0041
Echinococcus multilocularis GPCR, family 2 0.0063 0.0062 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0044 0.0902
Giardia lamblia 20S proteasome alpha subunit 7 0.0022 0.0006 0.0044
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0035 0.0025 0.0024
Brugia malayi SET domain containing protein 0.0034 0.0023 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0002 0.0015
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0103 0.0116 0.0115
Schistosoma mansoni tyrosine kinase 0.0103 0.0116 0.0353
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0036 0.0026 0.0078
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0136 0.0161 0.0489
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0022 0.0006 0.0005
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0049 0.0044 0.0085
Schistosoma mansoni hypothetical protein 0.0036 0.0025 0.0077
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0141 0.0167 0.066
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0092 0.0101 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0044 0.0373
Echinococcus granulosus nmda type glutamate receptor 0.0029 0.0016 0.0015
Trypanosoma cruzi Aminopeptidase M1, putative 0.0141 0.0167 0.066
Schistosoma mansoni hypothetical protein 0.0098 0.011 0.0333
Loa Loa (eye worm) tubulin beta-4 chain 0.0025 0.0011 0.0019
Onchocerca volvulus Chorion peroxidase homolog 0.0139 0.0164 0.2624
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0022 0.0006 0.0172
Schistosoma mansoni aminopeptidase A (M01 family) 0.0049 0.0044 0.0133
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0041 0.0032 0.0096
Onchocerca volvulus 0.002 0.0004 0.005
Schistosoma mansoni memapsin-2 (A01 family) 0.2163 0.2894 0.8811
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0022 0.0006 0.0133
Trypanosoma cruzi metacaspase, putative 0.0018 0.0002 0.0007
Plasmodium falciparum metacaspase 1 0.0018 0.0002 0.0046
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0033 0.0022 0.0067
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0022 0.0006 0.0055
Schistosoma mansoni hypothetical protein 0.002 0.0005 0.0014
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0025 0.0024
Toxoplasma gondii proteasome subunit alpha1, putative 0.0022 0.0006 0.0133
Schistosoma mansoni hypothetical protein 0.0098 0.011 0.0333
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) fli-1 protein 0.023 0.0287 0.057
Schistosoma mansoni caspase-7 (C14 family) 0.0061 0.0059 0.0179
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0033 0.0022 0.0453
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Schistosoma mansoni Dab2-interacting protein-like 0.002 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus GPCR family 2 0.0063 0.0062 0.0061
Echinococcus multilocularis tyrosine protein kinase HCK 0.0067 0.0068 0.0066
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0056 0.0055
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0002 0.0046
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0118 0.0136 0.054
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0268 0.0339 0.1031
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0004
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus neuropeptide FF receptor 2 0.0136 0.0161 0.0159
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0049 0.0044 0.0133
Loa Loa (eye worm) proteasome subunit beta type 2 0.0022 0.0006 0.001
Onchocerca volvulus 0.0186 0.0228 0.3666
Leishmania major proteasome alpha 2 subunit, putative 0.0022 0.0006 0.0026
Echinococcus multilocularis proteasome subunit beta type 7 0.0022 0.0006 0.0005
Brugia malayi Sex muscle abnormal protein 5 0.0036 0.0026 0.0049
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0268 0.0339 0.0673
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0155 0.0186 0.0737
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0177 0.0216 0.0215
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0022 0.0187
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0011 0.001
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0108 0.0107
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0136 0.0161 0.0159
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0118 0.0136 0.054
Echinococcus multilocularis kelch ECH associated protein 1 0.0465 0.0604 0.0603
Echinococcus granulosus Chromo domain 0.0033 0.0022 0.0021
Echinococcus multilocularis neuropeptides capa receptor 0.0136 0.0161 0.0159
Onchocerca volvulus 0.002 0.0004 0.005
Echinococcus granulosus chromobox protein 2 0.0569 0.0745 0.0743
Echinococcus multilocularis cpg binding protein 0.0031 0.0019 0.0018
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0092 0.0101 0.0306
Loa Loa (eye worm) hypothetical protein 0.0147 0.0175 0.0347
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Brugia malayi neuropeptide F receptor 0.0136 0.0161 0.0318
Onchocerca volvulus 0.0136 0.0161 0.2574
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0022 0.0006 0.0055
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0141 0.0167 0.1422
Onchocerca volvulus 0.0139 0.0164 0.2624
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0141 0.0167 0.0165
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0022 0.0006 0.0005
Brugia malayi Variant SH3 domain containing protein 0.002 0.0005 0.0006
Loa Loa (eye worm) animal heme peroxidase 0.0139 0.0164 0.0324
Echinococcus multilocularis proteasome subunit alpha type 2 0.0022 0.0006 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0025 0.01
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Loa Loa (eye worm) helicase 0.0033 0.0022 0.0041
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0155 0.0186 0.3759
Toxoplasma gondii aminopeptidase N protein 0.0049 0.0044 0.0904
Onchocerca volvulus 0.0136 0.0161 0.2574
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0042 0.0126
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0028 0.0084
Loa Loa (eye worm) ribonucleoside-diphosphate reductase large subunit 0.0198 0.0244 0.0484
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Echinococcus granulosus peregrin 0.003 0.0017 0.0016
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0022 0.0006 0.0133
Schistosoma mansoni hypothetical protein 0.0136 0.0161 0.0489
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0022 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0063 0.0062 0.0121
Echinococcus granulosus tyrosine kinase 0.002 0.0004 0.0003
Brugia malayi proteasome subunit alpha type 3 0.0022 0.0006 0.001
Brugia malayi Protein kinase domain containing protein 0.002 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.012 0.0139 0.0275
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0022 0.0006 0.0026
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0022 0.0006 0.0026
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.002 0.0005 0.0003
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0103 0.0116 0.0115
Brugia malayi jmjC domain containing protein 0.0037 0.0028 0.0053
Leishmania major proteasome alpha 7 subunit, putative 0.0022 0.0006 0.0026
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.002 0.0005 0.0003
Echinococcus multilocularis dro:myosuppressin receptor 0.0136 0.0161 0.0159
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0022 0.0006 0.0172
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0031 0.0264
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0022 0.0006 0.0019
Schistosoma mansoni hypothetical protein 0.0124 0.0144 0.0438
Trypanosoma brucei beta tubulin 0.0025 0.0011 0.0043
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0136 0.0161 0.0159
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0136 0.0161 0.0489
Onchocerca volvulus 0.0136 0.0161 0.2574
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0022 0.0006 0.0172
Echinococcus granulosus proteasome subunit alpha type 2 0.0022 0.0006 0.0005
Echinococcus multilocularis Spectrin alpha actinin 0.002 0.0005 0.0003
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0049 0.0044 0.0133
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0091 0.01 0.0304
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0155 0.0186 0.1587
Echinococcus multilocularis fmrfamide receptor 0.0136 0.0161 0.0159
Echinococcus granulosus chromobox protein 1 0.0033 0.0022 0.0021
Onchocerca volvulus Dual oxidase homolog 0.0139 0.0164 0.2624
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0022 0.0828
Schistosoma mansoni histamine h1 receptor 0.0136 0.0161 0.0489
Onchocerca volvulus 0.0036 0.0025 0.0387
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0056 0.1063
Loa Loa (eye worm) neuropeptide F receptor 0.0136 0.0161 0.0318
Echinococcus granulosus tubulin subunit beta 0.0025 0.0011 0.001
Giardia lamblia Proteasome subunit beta type 2 0.0022 0.0006 0.0044
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0022 0.0586
Schistosoma mansoni cell polarity protein 0.0048 0.0042 0.0129
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0141 0.0167 0.0165
Loa Loa (eye worm) hypothetical protein 0.0049 0.0044 0.0085
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0092 0.0101 0.0306
Giardia lamblia 20S proteasome alpha subunit 1 0.0022 0.0006 0.0044
Echinococcus granulosus c src tyrosine kinase 0.0041 0.0032 0.003
Onchocerca volvulus Peroxidase homolog 0.0139 0.0164 0.2624
Brugia malayi Guanylate kinase family protein 0.0069 0.007 0.0137
Trichomonas vaginalis Heterochromatin protein, putative 0.0033 0.0022 0.0187
Echinococcus multilocularis protein patched 0.0778 0.1026 0.1025
Brugia malayi hypothetical protein 0.0033 0.0022 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0022 0.0187
Echinococcus granulosus tyrosine protein kinase Blk 0.0083 0.0089 0.0087
Loa Loa (eye worm) hypothetical protein 0.0268 0.0339 0.0673
Plasmodium falciparum plasmepsin IV 0.0295 0.0375 1
Loa Loa (eye worm) hypothetical protein 0.0376 0.0484 0.0963
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Entamoeba histolytica hypothetical protein 0.002 0.0005 0.0007
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.002 0.0005 0.0003
Echinococcus granulosus leukotriene A 4 hydrolase 0.0049 0.0044 0.0042
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0002 0.0015
Schistosoma mansoni dopamine-beta-monooxygenase 0.012 0.0139 0.0424
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0017 0.0016
Schistosoma mansoni notch 0.0018 0.0001 0.0004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0083 0.0089 0.0087
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0022 0.0006 0.0133
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0886 0.1172 1
Trypanosoma cruzi beta tubulin, putative 0.0025 0.0011 0.0043
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0022 0.0006 0.0172
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0155 0.0186 0.0737
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0022 0.0006 0.0005
Echinococcus multilocularis Chromobox protein 3 0.0033 0.0022 0.0021
Giardia lamblia PHD finger protein 15 0.003 0.0017 0.0135
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0056 0.0222
Echinococcus multilocularis Kelch repeat type 1 0.0466 0.0606 0.0604
Echinococcus granulosus g protein coupled receptor 0.0136 0.0161 0.0159
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0103 0.0116 0.0115
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0049 0.0044 0.0042
Plasmodium falciparum metacaspase-like protein 0.0018 0.0002 0.0046
Schistosoma mansoni hypothetical protein 0.0098 0.011 0.0333
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0022 0.0006 0.0019
Loa Loa (eye worm) PAS-3 protein 0.0022 0.0006 0.001
Echinococcus granulosus neuropeptide receptor A26 0.0136 0.0161 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0039
Plasmodium falciparum heterochromatin protein 1 0.0033 0.0022 0.0586
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0022 0.0006 0.0172
Leishmania major proteasome beta 2 subunit, putative 0.0022 0.0006 0.0026
Schistosoma mansoni hypothetical protein 0.0098 0.011 0.0333
Echinococcus multilocularis neuropeptide receptor 0.0136 0.0161 0.0159
Trichomonas vaginalis ribonucleoside-diphosphate reductase alpha chain, putative 0.0167 0.0202 0.1724
Plasmodium vivax aspartyl protease, putative 0.0147 0.0175 0.468
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0002 0.0015
Echinococcus granulosus kelch ECH associated protein 1 like 0.0465 0.0604 0.0603
Brugia malayi Peroxidasin 0.0139 0.0164 0.0324
Trichomonas vaginalis tubulin alpha chain, putative 0.0025 0.0011 0.0092
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0011 0.001
Schistosoma mansoni peroxidasin 0.0139 0.0164 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.0778 0.1026 0.8752
Schistosoma mansoni thyroid hormone receptor 0.0134 0.0157 0.0479
Plasmodium vivax aspartyl proteinase, putative 0.0147 0.0175 0.468
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0049 0.0044 0.1168
Entamoeba histolytica hypothetical protein 0.0177 0.0216 1
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.002 0.0005 0.0003
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0035 0.0025 0.0024
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0049 0.0044 0.1168
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0033 0.0022 0.0021
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0041 0.0032 0.003
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0376 0.0484 0.0963
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0144 0.0143
Treponema pallidum ribonucleotide-diphosphate reductase subunit alpha 0.0198 0.0244 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0161 0.0489
Echinococcus multilocularis orexin receptor type 2 0.0136 0.0161 0.0159
Entamoeba histolytica aminopeptidase, putative 0.0141 0.0167 0.7654
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0144 0.0143
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0061 0.0059 0.0116
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0141 0.0167 0.066
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0022 0.0006 0.0097
Onchocerca volvulus 0.0033 0.0022 0.0333
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Trypanosoma brucei Aminopeptidase M1, putative 0.0141 0.0167 0.066
Toxoplasma gondii beta-tubulin, putative 0.0025 0.0011 0.0223
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0103 0.0116 0.0115
Leishmania major C-8 sterol isomerase-like protein 0.0748 0.0985 0.3904
Echinococcus multilocularis protein dispatched 1 0.0778 0.1026 0.1025
Brugia malayi Variant SH3 domain containing protein 0.002 0.0005 0.0006
Brugia malayi beta-tubulin, identical 0.0025 0.0011 0.0019
Leishmania major ribonucleoside-diphosphate reductase large chain, putative 0.0198 0.0244 0.0966
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0022 0.0006 0.0172
Echinococcus granulosus orexin receptor type 2 0.0136 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Brugia malayi M-phase phosphoprotein, mpp8 0.0033 0.0022 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0039
Echinococcus granulosus caspase 2 0.0061 0.0059 0.0058
Brugia malayi follicle stimulating hormone receptor 0.0136 0.0161 0.0318
Echinococcus granulosus 7TM GPCR rhodopsin 0.0136 0.0161 0.0159
Echinococcus multilocularis g protein coupled receptor 0.0136 0.0161 0.0159
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0004 0.0006
Echinococcus multilocularis neuropeptide receptor 0.0136 0.0161 0.0159
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0022 0.0006 0.0097
Echinococcus multilocularis disks large 3 0.0048 0.0042 0.0041
Schistosoma mansoni amine GPCR 0.0136 0.0161 0.0489
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0376 0.0484 1
Brugia malayi Fes/CIP4 homology domain containing protein 0.002 0.0005 0.0006
Trypanosoma brucei protein kinase, putative 0.0049 0.0044 0.0173
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0002 0.0015
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0268 0.0339 0.0337
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0446 0.0578 0.1761
Brugia malayi neuropeptide F receptor 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Brugia malayi jmjC domain containing protein 0.0097 0.0108 0.0212
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0141 0.0167 0.1422
Echinococcus granulosus tyrosine protein kinase Fps85D 0.002 0.0004 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0039
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0147 0.0175 0.0534
Onchocerca volvulus LIM and SH3 domain protein homolog 0.002 0.0005 0.0052
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0285 0.0361 0.0717
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0035 0.0025 0.0047
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0177 0.0216 0.0215
Loa Loa (eye worm) hypothetical protein 0.0278 0.0352 0.0699
Trypanosoma brucei metacaspase 0.0018 0.0002 0.0007
Echinococcus granulosus kelch ECH associated protein 1 like 0.0465 0.0604 0.0603
Schistosoma mansoni alpha-1 adrenergic receptor 0.0136 0.0161 0.0489
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0118 0.0136 0.0135
Plasmodium falciparum plasmepsin VII 0.0147 0.0175 0.468
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0022 0.0006 0.0133
Echinococcus multilocularis peroxidasin 0.0139 0.0164 0.0163
Giardia lamblia Beta tubulin 0.0025 0.0011 0.0081
Echinococcus granulosus tyrosine protein kinase Srms 0.002 0.0004 0.0003
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0022 0.0006 0.0005
Echinococcus multilocularis nmda type glutamate receptor 0.0029 0.0016 0.0015
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0044 0.0173
Schistosoma mansoni tubulin subunit beta 0.0025 0.0011 0.0033
Echinococcus multilocularis endothelin converting enzyme 1 0.0376 0.0484 0.0483
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0155 0.0186 0.0566
Entamoeba histolytica tubulin family protein 0.0025 0.0011 0.0303
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0002 0.0007
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.002 0.0005 0.0003
Schistosoma mansoni hypothetical protein 0.0136 0.016 0.0488
Giardia lamblia 20S proteasome alpha subunit 3 0.0022 0.0006 0.0044
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0035 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Brugia malayi Animal haem peroxidase family protein 0.0139 0.0164 0.0324
Schistosoma mansoni endothelin-converting enzyme-related 0.0092 0.0101 0.0306
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0056 0.0055
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0778 0.1026 0.2044
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0022 0.0006 0.0097
Giardia lamblia 20S proteasome alpha subunit 5 0.0022 0.0006 0.0044
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0022 0.0006 0.0026
Echinococcus granulosus neuropeptide Y receptor 0.0136 0.0161 0.0159
Schistosoma mansoni thyroid hormone receptor 0.0134 0.0157 0.0479
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0049 0.0044 0.0173
Entamoeba histolytica protein kinase, putative 0.002 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0136 0.0161 0.0489
Plasmodium falciparum plasmepsin I 0.0295 0.0375 1
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Trypanosoma brucei beta tubulin 0.0025 0.0011 0.0043
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0136 0.0161 0.0159
Schistosoma mansoni notch 0.0018 0.0001 0.0004
Brugia malayi 20S proteasome alpha5 subunit 0.0022 0.0006 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Echinococcus granulosus allatostatin A receptor 0.0136 0.0161 0.0159
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0022 0.0006 0.0005
Echinococcus granulosus peptide allatostatin:somatostatin 0.0136 0.0161 0.0159
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0044 0.0173
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0103 0.0116 0.0115
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0011 0.001
Onchocerca volvulus 0.0042 0.0034 0.0534
Echinococcus granulosus apoptotic protease activating factor 1 0.0042 0.0034 0.0033
Echinococcus multilocularis tyrosine kinase 0.002 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0428 0.0554 0.1103
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0022 0.0006 0.0026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0136 0.0161 0.0159
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0147 0.0175 0.0534
Onchocerca volvulus Peroxidasin homolog 0.0139 0.0164 0.2624
Loa Loa (eye worm) hypothetical protein 0.0337 0.0431 0.0858
Brugia malayi glutaminase DH11.1 0.0272 0.0343 0.0682
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0004
Onchocerca volvulus 0.002 0.0005 0.0052
Brugia malayi Animal haem peroxidase family protein 0.0139 0.0164 0.0324
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0028 0.0026
Brugia malayi Fli-1 protein 0.023 0.0287 0.057
Schistosoma mansoni biogenic amine receptor 0.0136 0.0161 0.0489
Schistosoma mansoni hypothetical protein 0.0063 0.0062 0.0188
Echinococcus multilocularis inhibitor of apoptosis protein 0.0268 0.0339 0.0337
Brugia malayi Peptidase family M1 containing protein 0.0477 0.0621 0.1236
Echinococcus granulosus G protein coupled receptor 139 0.0136 0.0161 0.0159
Schistosoma mansoni notch 0.0018 0.0001 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0147 0.0175 0.0534
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0056 0.0468
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0136 0.0161 0.0489
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0022 0.0006 0.0172
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.002 0.0005 0.0003
Echinococcus multilocularis tyrosine protein kinase Srms 0.0083 0.0089 0.0087
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0022 0.0006 0.0055
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0022 0.0006 0.0026
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.019 0.0233 0.0709
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0036 0.0026 0.0049
Brugia malayi MAP kinase sur-1 0.0049 0.0044 0.0085
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0053 0.1088
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0098 0.011 0.0333
Schistosoma mansoni hypothetical protein 0.0063 0.0062 0.0188
Loa Loa (eye worm) zinc metallopeptidase 4 0.0092 0.0101 0.0198
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0022 0.0006 0.0019
Trichomonas vaginalis tubulin gamma chain, putative 0.0025 0.0011 0.0092
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0006
Entamoeba histolytica hypothetical protein 0.0033 0.0022 0.0828
Brugia malayi ribonucleoside-diphosphate reductase large chain, putative 0.0198 0.0244 0.0484
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0056 0.0109
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0268 0.0339 0.0673
Schistosoma mansoni chromobox protein 0.0033 0.0022 0.0067
Brugia malayi proteasome subunit beta type 3 0.0022 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus multilocularis G-protein coupled receptor, putative 0.0136 0.0161 0.0159
Onchocerca volvulus Notchless protein homolog 0.0022 0.0006 0.0083
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0161 0.0489
Onchocerca volvulus 0.0136 0.0161 0.2574
Brugia malayi replication factor A 73 kDa subunit 0.0035 0.0025 0.0047
Brugia malayi Peptidase family M13 containing protein 0.0376 0.0484 0.0963
Echinococcus granulosus beta tubulin 0.0025 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0295 0.0375 0.0373
Loa Loa (eye worm) glutaminase 2 0.0272 0.0343 0.0682
Onchocerca volvulus 0.0136 0.0161 0.2574
Onchocerca volvulus 0.0136 0.0161 0.2574
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0022 0.0006 0.0019
Onchocerca volvulus 0.002 0.0005 0.0052
Plasmodium falciparum proteasome subunit beta type-4 0.0022 0.0006 0.0172
Schistosoma mansoni hypothetical protein 0.0466 0.0606 0.1844
Brugia malayi Animal haem peroxidase family protein 0.0139 0.0164 0.0324
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0295 0.0375 0.7737
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0028 0.0053
Echinococcus multilocularis nostrin 0.002 0.0005 0.0003
Leishmania major hypothetical protein, conserved 0.0036 0.0025 0.01
Schistosoma mansoni amine GPCR 0.0136 0.0161 0.0489
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0018 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Echinococcus granulosus endothelin converting enzyme 1 0.0376 0.0484 0.0483
Entamoeba histolytica BAR/SH3 domain containing protein 0.002 0.0005 0.0007
Echinococcus granulosus sex peptide receptor 0.0136 0.0161 0.0159
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0044 0.0373
Brugia malayi aspartic protease BmAsp-2, identical 0.0147 0.0175 0.0347
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0056 0.0222
Echinococcus granulosus neuropeptide receptor 0.0136 0.0161 0.0159
Schistosoma mansoni hypothetical protein 0.0098 0.011 0.0333
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0136 0.0161 0.0318
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0033 0.0022 0.0586
Brugia malayi Associated with TFs and helicases family protein 0.0033 0.0022 0.0041
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0031 0.0264
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0042 0.004
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus src region 0.002 0.0005 0.0003
Schistosoma mansoni chromobox protein 0.0033 0.0022 0.0067
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0268 0.0339 0.0337
Schistosoma mansoni notch 0.0018 0.0001 0.0004
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0022 0.0006 0.0097
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0041
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.019 0.0233 0.0709
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0136 0.0161 0.0318
Echinococcus granulosus neuropeptide s receptor 0.0136 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Toxoplasma gondii ribonucleoside-diphosphate reductase large chain 0.0198 0.0244 0.5038
Toxoplasma gondii proteasome subunit alpha type, putative 0.0022 0.0006 0.0133
Echinococcus multilocularis kelch ECH associated protein 1 0.0465 0.0604 0.0603
Onchocerca volvulus Neuropeptide F receptor homolog 0.0136 0.0161 0.2574
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0022 0.0006 0.0026
Schistosoma mansoni neprilysin 0.0098 0.011 0.0333
Brugia malayi Proteasome A-type and B-type family protein 0.0022 0.0006 0.001
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0036 0.0025 0.0674
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0108 0.0107
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0022 0.0006 0.0026
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0056 0.0479
Brugia malayi Cell death protein 3 precursor 0.0061 0.0059 0.0115
Brugia malayi Variant SH3 domain containing protein 0.002 0.0005 0.0006
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0022 0.0006 0.0026
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.0022 0.0067
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0022 0.0006 0.0172
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0011 0.001
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0056 0.1498
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.1889 0.2524 0.5032
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0022 0.0006 0.0026
Echinococcus multilocularis Niemann Pick C1 protein 0.0778 0.1026 0.1025
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.002 0.0005 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0002 0.0015
Schistosoma mansoni septate junction protein 0.0018 0.0001 0.0004
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0118 0.0136 0.2813
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0136 0.0161 0.0318
Onchocerca volvulus 0.0136 0.0161 0.2574
Echinococcus granulosus expressed protein 0.002 0.0005 0.0003
Echinococcus granulosus proteasome subunit alpha type 6 0.0022 0.0006 0.0005
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0022 0.0006 0.0172
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0022 0.0006 0.0005
Brugia malayi G-protein coupled receptor 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0091 0.01 0.0197
Schistosoma mansoni apoptosis stimulating of P53 0.002 0.0005 0.0014
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0136 0.0161 0.0159
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0027 0.0229
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0022 0.0006 0.0044
Entamoeba histolytica protein kinase, putative 0.0067 0.0068 0.2987
Loa Loa (eye worm) G-protein coupled receptor 0.0136 0.0161 0.0318
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0136 0.0161 0.0318
Brugia malayi proteasome subunit beta type 2 0.0022 0.0006 0.001
Brugia malayi Proteasome A-type and B-type family protein 0.0155 0.0186 0.0369
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0022 0.0006 0.0026
Brugia malayi ORL1-like opioid receptor 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0199 0.0245 0.0487
Leishmania major proteasome beta 3 subunit, putative 0.0022 0.0006 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0026 0.0223
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0059 0.0056 0.2539
Echinococcus granulosus chromobox protein 1 0.0033 0.0022 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0044 0.0373
Schistosoma mansoni hypothetical protein 0.0136 0.0161 0.0489
Echinococcus granulosus dnaJ subfamily B 0.0421 0.0545 0.0544
Echinococcus granulosus ribonucleoside diphosphate reductase large 0.0198 0.0244 0.0243
Echinococcus multilocularis apoptotic protease activating factor 1 0.0042 0.0034 0.0033
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0022 0.0006 0.0044
Brugia malayi Protein kinase domain containing protein 0.002 0.0004 0.0006
Brugia malayi hypothetical protein 0.0147 0.0175 0.0347
Echinococcus multilocularis serotonin receptor 0.0136 0.0161 0.0159
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0022 0.0187
Schistosoma mansoni cell polarity protein 0.0034 0.0022 0.0068
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0022 0.0006 0.0055
Leishmania major proteasome beta 7 subunit, putative 0.0022 0.0006 0.0026
Echinococcus multilocularis tyrosine protein kinase shark 0.002 0.0004 0.0003
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0022 0.0006 0.0172
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0147 0.0175 0.3621
Echinococcus multilocularis somatostatin receptor 0.0136 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus multilocularis tyrosine protein kinase Blk 0.0083 0.0089 0.0087
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Echinococcus multilocularis chromobox protein 1 0.0033 0.0022 0.0021
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0044 0.0173
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Echinococcus granulosus serotonin receptor 0.0136 0.0161 0.0159
Echinococcus granulosus g-protein coupled receptor 0.0136 0.0161 0.0159
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0141 0.0167 0.0165
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) animal heme peroxidase 0.0139 0.0164 0.0324
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0022 0.0006 0.0172
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0136 0.0161 0.0159
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0022 0.0006 0.001
Echinococcus multilocularis Tubulin beta 2C chain 0.0025 0.0011 0.001
Echinococcus granulosus fch and double sh3 domains protein 2 0.002 0.0005 0.0003
Plasmodium vivax plasmepsin V, putative 0.0147 0.0175 0.468
Brugia malayi Serotonin receptor 0.0136 0.0161 0.0318
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0049 0.0044 0.0042
Brugia malayi G-protein coupled receptor 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Loa Loa (eye worm) hypothetical protein 0.0268 0.0339 0.0673
Echinococcus granulosus kelch ECH associated protein 1 0.0465 0.0604 0.0603
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0044 0.0373
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0022 0.0006 0.0097
Onchocerca volvulus Cell death protein 3 homolog 0.0061 0.0059 0.093
Schistosoma mansoni hypothetical protein 0.0098 0.011 0.0333
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0141 0.0167 0.0165
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Trypanosoma brucei metacaspase MCA3 0.0018 0.0002 0.0007
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0092 0.0101 0.0306
Brugia malayi hypothetical protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.006 0.0116
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0022 0.0006 0.0026
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0044 0.0173
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.002 0.0005 0.0018
Echinococcus granulosus Tubulin beta 2C chain 0.0025 0.0011 0.001
Schistosoma mansoni hypothetical protein 0.0042 0.0034 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0002 0.0015
Schistosoma mansoni amine GPCR 0.0136 0.0161 0.0489
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0022 0.0006 0.0172
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Loa Loa (eye worm) TATA binding protein associated factor 0.0049 0.0044 0.0085
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit alpha 0.0167 0.0202 1
Schistosoma mansoni notch 0.0018 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus proteasome subunit beta t family 0.0022 0.0006 0.0005
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0295 0.0375 0.0373
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0049 0.0044 0.0173
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0062 0.0188
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0062 0.0061
Brugia malayi Variant SH3 domain containing protein 0.0036 0.0026 0.0049
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Echinococcus granulosus tyrosine protein kinase Lyn 0.0104 0.0117 0.0115
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0022 0.0187
Onchocerca volvulus 0.002 0.0004 0.005
Schistosoma mansoni gabp alpha 0.0076 0.0079 0.0241
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Trypanosoma brucei metacaspase 5, putative 0.0018 0.0002 0.0007
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0103 0.0116 0.0115
Schistosoma mansoni notch 0.0018 0.0001 0.0004
Schistosoma mansoni signal transducing adapter molecule (stam) 0.002 0.0005 0.0014
Trypanosoma brucei proteasome beta 7 subunit 0.0022 0.0006 0.0026
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0022 0.0006 0.0172
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0118 0.0136 0.0135
Loa Loa (eye worm) TK protein kinase 0.0067 0.0068 0.0132
Plasmodium vivax heterochromatin protein 1, putative 0.0033 0.0022 0.0586
Loa Loa (eye worm) hypothetical protein 0.0295 0.0375 0.0745
Brugia malayi SH2 domain containing protein 0.002 0.0004 0.0006
Schistosoma mansoni formin binding protein and related proteins 0.002 0.0005 0.0014
Brugia malayi Calcitonin receptor-like protein seb-1 0.0199 0.0245 0.0487
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0136 0.0161 0.2574
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0022 0.0006 0.0026
Brugia malayi Tubulin beta-1 chain 0.0025 0.0011 0.0019
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0018 0.0002 0.0001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0147 0.0175 0.0534
Brugia malayi sulfakinin receptor protein 0.0136 0.0161 0.0318
Schistosoma mansoni neuropeptide f receptor 76f 0.0136 0.0161 0.0489
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0022 0.0006 0.0097
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0022 0.0006 0.0026
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.1889 0.2524 0.2523
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0155 0.0186 0.1578
Loa Loa (eye worm) hypothetical protein 0.0139 0.0164 0.0324
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0049 0.0044 0.0173
Mycobacterium ulcerans zinc metalloprotease 0.0376 0.0484 0.1902
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0141 0.0167 0.0165
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0022 0.0006 0.0019
Brugia malayi Protein kinase domain containing protein 0.002 0.0004 0.0006
Plasmodium falciparum cysteine repeat modular protein 1 0.0036 0.0025 0.0674
Mycobacterium ulcerans aminopeptidase N PepN 0.0141 0.0167 0.0641
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0022 0.0006 0.0026
Echinococcus granulosus tachykinin peptides receptor 99D 0.0136 0.0161 0.0159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0161 0.0489
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0161 0.0489
Chlamydia trachomatis transcriptional repressor NrdR 0.0031 0.0019 0.0578
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0022 0.0006 0.0005
Toxoplasma gondii EGF family domain-containing protein 0.0018 0.0001 0.0027
Leishmania major beta tubulin 0.0025 0.0011 0.0043
Toxoplasma gondii peptidase family M13 protein 0.0376 0.0484 1
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0022 0.0006 0.0026
Plasmodium vivax proteasome subunit beta type-6, putative 0.0022 0.0006 0.0172
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0161 0.0159
Brugia malayi Animal haem peroxidase family protein 0.0139 0.0164 0.0324
Plasmodium vivax metacaspase 1, putative 0.0018 0.0002 0.0046
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0103 0.0116 0.0115
Plasmodium vivax proteasome subunit beta type-4, putative 0.0022 0.0006 0.0172
Loa Loa (eye worm) glutaminase 0.0272 0.0343 0.0682
Trichomonas vaginalis tubulin beta chain, putative 0.0025 0.0011 0.0092
Schistosoma mansoni inhibitor of apoptosis protein 0.0268 0.0339 0.1031
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0041
Onchocerca volvulus 0.0139 0.0164 0.2624
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0103 0.0116 0.0115
Trypanosoma cruzi metacaspase, putative 0.0018 0.0002 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0136 0.0161 0.0159
Echinococcus multilocularis fch and double sh3 domains protein 2 0.002 0.0005 0.0003
Onchocerca volvulus Deterin homolog 0.0268 0.0339 0.5444
Loa Loa (eye worm) lethal(1)discs large-1 tumor suppressor 0.0046 0.0039 0.0075
Echinococcus granulosus proteasome subunit beta type 6 0.0022 0.0006 0.0005
Loa Loa (eye worm) aminopeptidase N 0.0141 0.0167 0.033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0031 0.0264
Echinococcus multilocularis g-protein coupled receptor 0.0136 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0227 0.0283 0.0561
Loa Loa (eye worm) aspartyl protease 6 0.0147 0.0175 0.0347
Onchocerca volvulus 0.0136 0.0161 0.2574
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0049 0.0044 0.0173
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0033 0.0031
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0022 0.0006 0.0172
Leishmania major proteasome alpha 3 subunit, putative 0.0022 0.0006 0.0026
Brugia malayi putative neuropeptide receptor 0.0136 0.0161 0.0318
Onchocerca volvulus 0.0136 0.0161 0.2574
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0155 0.0186 0.0737
Entamoeba histolytica hypothetical protein 0.002 0.0005 0.0007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0056 0.1498
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Giardia lamblia 20S proteasome alpha subunit 4 0.0022 0.0006 0.0044
Onchocerca volvulus 0.0141 0.0167 0.2669
Plasmodium falciparum plasmepsin IX 0.0147 0.0175 0.468
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0778 0.1026 0.3123
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0022 0.0006 0.0026
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) 0.0167 0.0202 0.4111
Echinococcus multilocularis NCK adaptor protein 0.0036 0.0026 0.0025
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0103 0.0116 0.0115
Schistosoma mansoni tyrosine kinase 0.0103 0.0116 0.0353
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0004
Echinococcus multilocularis tissue type plasminogen activator 0.0036 0.0025 0.0024
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0044 0.0362
Plasmodium vivax aspartyl protease, putative 0.0147 0.0175 0.468
Mycobacterium ulcerans glutaminase 0.0272 0.0343 0.1342
Loa Loa (eye worm) hypothetical protein 0.0136 0.0161 0.0318
Loa Loa (eye worm) hypothetical protein 0.0049 0.0044 0.0085
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.1889 0.2524 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0136 0.0161 0.0489
Entamoeba histolytica hypothetical protein 0.002 0.0005 0.0007
Leishmania major proteasome beta 5 subunit, putative 0.0155 0.0186 0.0737
Echinococcus granulosus alpha 1A adrenergic receptor 0.0136 0.0161 0.0159
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0022 0.0006 0.0026
Onchocerca volvulus 0.0136 0.0161 0.2574
Echinococcus granulosus intersectin 2 0.002 0.0005 0.0003
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0022 0.0006 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0187
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0004
Echinococcus granulosus subfamily T1A non peptidase ue 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0555 0.0725 0.1443
Schistosoma mansoni glutaminase 0.0272 0.0343 0.1045
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0022 0.0006 0.0055
Schistosoma mansoni biogenic amine (5HT) receptor 0.0136 0.0161 0.0489
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0155 0.0186 0.3776
Echinococcus multilocularis growth factor receptor bound protein 2 0.0036 0.0026 0.0025
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0049 0.0044 0.1168
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0056 0.0202

Activities

Activity type Activity value Assay description Source Reference
Kd (functional) = 6.7 Antagonistic activity against alpha-1 adrenergic receptor in isolated rat anococcygeus muscle ChEMBL. 2838634
Kd (functional) = 8.1 Antagonistic activity against alpha-2 adrenergic receptor in rat vas deferens ChEMBL. 2838634
pA2 (functional) = 6.7 Antagonistic activity against alpha-1 adrenergic receptor in isolated rat anococcygeus muscle ChEMBL. 2838634
pA2 (functional) = 8.1 Antagonistic activity against alpha-2 adrenergic receptor in rat vas deferens ChEMBL. 2838634
Ratio (binding) = 25 Selectivity ratio represented as antilog (alpha-2 pA2 - alpha-1 pA2) ChEMBL. 2838634

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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