Detailed information for compound 546334

Basic information

Technical information
  • TDR Targets ID: 546334
  • Name: 4-(diethylamino)benzenediazonium chloride
  • MW: 211.691 | Formula: C10H14ClN3
  • H donors: 0 H acceptors: 0 LogP: 4.24 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(c1ccc(cc1)[N+]#N)CC.[Cl-]
  • InChi: 1S/C10H14N3.ClH/c1-3-13(4-2)10-7-5-9(12-11)6-8-10;/h5-8H,3-4H2,1-2H3;1H/q+1;/p-1
  • InChiKey: YFCXTPKUVYRXFI-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • 4-diethylaminobenzenediazonium chloride
  • 148-90-3
  • 21906-90-1
  • 80246-51-1
  • 6217-19-2
  • Benzenediazonium, 4-(diethylamino)-, chloride
  • EINECS 205-730-5
  • p-(Diethylamino)benzenediazonium chloride

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax ornithine aminotransferase, putative 0.0086 0.0118 0.1434
Brugia malayi Steroid receptor seven-up type 2 0.0102 0.015 0.018
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0048 0.004 0.0186
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0021 0.0155
Trypanosoma brucei hypothetical protein, conserved 0.0378 0.07 0.5802
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.036 0.0665 0.0801
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.0032 0.0827
Plasmodium vivax histone acetyltransferase GCN5, putative 0.014 0.0224 0.2995
Loa Loa (eye worm) MBOAT family protein 0.4178 0.8295 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.017 0.0284 0.0342
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0284 0.0284
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.002 0.002
Onchocerca volvulus 0.036 0.0665 0.33
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0048 0.0042 0.0041
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0085 0.0116 0.0936
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0029 0.0003 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0102 0.015 0.018
Loa Loa (eye worm) hypothetical protein 0.004 0.0025 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0044 0.0033 0.0064
Toxoplasma gondii cytochrome p450 superfamily protein 0.0044 0.0033 0.0308
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0299 0.0542 0.4493
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0074 0.0089
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0207 0.0359 0.0359
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0102 0.015 0.018
Plasmodium vivax ataxin-2 like protein, putative 0.0132 0.0208 0.2759
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0074 0.0089
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0029 0.0003 0.0012
Plasmodium vivax importin-beta 2, putative 0.0059 0.0064 0.0635
Schistosoma mansoni hypothetical protein 0.0311 0.0568 0.0684
Leishmania major mitochondrial DNA polymerase beta 0.0631 0.1207 1
Trypanosoma cruzi glycerol uptake protein, putative 0.036 0.0665 0.5496
Echinococcus multilocularis muscleblind protein 0.1718 0.338 0.3379
Leishmania major GTP-binding protein, putative 0.0044 0.0032 0.0245
Onchocerca volvulus 0.0098 0.0141 0.0699
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0026 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0102 0.015 0.018
Echinococcus granulosus histone lysine methyltransferase setb 0.0152 0.0248 0.0299
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0207 0.0359 0.0432
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0085 0.0116 0.056
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.002 0.0087
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.036 0.0665 0.0801
Echinococcus granulosus o acyltransferase membrane bound domain 0.036 0.0665 0.0801
Loa Loa (eye worm) hhat protein 0.036 0.0665 0.0801
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0378 0.07 0.1463
Echinococcus multilocularis Polycystic kidney disease protein 0.0063 0.0071 0.0071
Leishmania major DNA polymerase kappa, putative 0.004 0.0025 0.0182
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0084 0.0112 0.0135
Leishmania major glycerol uptake protein, putative 0.036 0.0665 0.5496
Schistosoma mansoni hypothetical protein 0.0113 0.017 0.0205
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.058 0.1104 0.1104
Brugia malayi Importin beta-1 subunit 0.0059 0.0064 0.0076
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0084 0.0112 0.0112
Echinococcus multilocularis nuclear receptor nhr 48 0.0048 0.0042 0.0041
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2414 0.477 1
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.036 0.0665 0.0801
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0086 0.0118 0.0142
Schistosoma mansoni RAR-like nuclear receptor 0.0102 0.015 0.018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0102 0.015 0.018
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0631 0.1207 1
Brugia malayi nuclear receptor NHR-88 0.0102 0.015 0.018
Trichomonas vaginalis penicillin-binding protein, putative 0.0378 0.07 0.3469
Schistosoma mansoni microtubule-associated protein tau 0.1541 0.3025 0.3646
Mycobacterium leprae putative cytochrome p450 0.0044 0.0033 0.0264
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0044 0.0033 0.0264
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0025 0.0029
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0042 0.0041
Mycobacterium ulcerans L-lysine aminotransferase 0.0086 0.0118 0.0994
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.0025 0.0205
Toxoplasma gondii histone lysine methyltransferase SET1 0.0355 0.0656 0.6582
Brugia malayi Cytochrome P450 family protein 0.0174 0.0292 0.0352
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0044 0.0033 0.0064
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0044 0.0033 0.0064
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0044 0.0033 0.0264
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0064 0.0527
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0044 0.0033 0.0264
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0207 0.0359 0.1771
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.0071 0.0071
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0085 0.0116 0.056
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0029 0.0003 0.0003
Schistosoma mansoni retinoic acid receptor RXR 0.0102 0.015 0.018
Trypanosoma cruzi PAB1-binding protein , putative 0.0132 0.0208 0.1704
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0085 0.0116 0.056
Loa Loa (eye worm) hypothetical protein 0.0059 0.0064 0.0076
Echinococcus granulosus survival motor neuron protein 1 0.0756 0.1456 0.1755
Trypanosoma cruzi cytochrome P450, putative 0.0064 0.0074 0.0589
Echinococcus granulosus nuclear receptor nhr 48 0.0048 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.0102 0.015 0.018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.0248 0.0299
Schistosoma mansoni inositol monophosphatase 0.0038 0.0021 0.0025
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Schistosoma mansoni alpha-glucosidase 0.0146 0.0237 0.0285
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0085 0.0116 0.056
Schistosoma mansoni inositol monophosphatase 0.0038 0.0021 0.0025
Leishmania major glycerol uptake protein, putative 0.036 0.0665 0.5496
Onchocerca volvulus 0.0063 0.0071 0.0353
Brugia malayi ecdysteroid receptor 0.0102 0.015 0.018
Leishmania major cytochrome p450-like protein 0.0044 0.0033 0.0254
Mycobacterium tuberculosis Probable lipase LipD 0.0378 0.07 0.1463
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.0032 0.0039
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0085 0.0116 0.056
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0048 0.0042 0.005
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0053 0.0064
Brugia malayi TAR-binding protein 0.0065 0.0074 0.0089
Echinococcus multilocularis thyroid hormone receptor alpha 0.0102 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0102 0.015 0.018
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0029 0.0003 0.0003
Schistosoma mansoni rab6-interacting 0.0063 0.0071 0.0086
Brugia malayi Thioredoxin reductase 0.0051 0.0047 0.0057
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0052 0.0049 0.0232
Brugia malayi nuclear hormone receptor family member nhr-6 0.0048 0.0042 0.005
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.0173 0.1415
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.0032 0.0297
Toxoplasma gondii exonuclease III APE 0.0062 0.0068 0.0659
Entamoeba histolytica hypothetical protein 0.0048 0.0041 0.0579
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0025 0.0205
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0074 0.0089
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0025 0.0182
Loa Loa (eye worm) hypothetical protein 0.0102 0.015 0.018
Brugia malayi hypothetical protein 0.0388 0.072 0.0868
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0013 0.0021
Schistosoma mansoni hypothetical protein 0.0113 0.017 0.0205
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0062 0.0068 0.0543
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0049 0.0043 0.0043
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0048 0.004 0.031
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0085 0.0116 0.056
Echinococcus granulosus GPCR family 2 0.0113 0.017 0.0205
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0117 0.0179 0.0369
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0058 0.0069
Brugia malayi photoreceptor-specific nuclear receptor 0.0102 0.015 0.018
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0044 0.0033 0.0064
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0025 0.0331
Toxoplasma gondii hypothetical protein 0.0071 0.0086 0.0843
Schistosoma mansoni ap endonuclease 0.0062 0.0068 0.0082
Echinococcus multilocularis mitogen activated protein kinase 3 0.0114 0.0173 0.0173
Trichomonas vaginalis ap endonuclease, putative 0.0062 0.0068 0.0325
Echinococcus multilocularis neuropeptide receptor A26 0.103 0.2003 0.2002
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0113
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0044 0.0033 0.0264
Schistosoma mansoni thyroid hormone receptor 0.0102 0.015 0.018
Plasmodium falciparum importin beta, putative 0.0059 0.0064 0.067
Echinococcus multilocularis dna polymerase eta 0.004 0.0025 0.0024
Echinococcus granulosus snurportin 1 0.0633 0.121 0.1458
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.036 0.0665 0.0801
Loa Loa (eye worm) hypothetical protein 0.0132 0.0208 0.025
Mycobacterium ulcerans lipase LipD 0.0378 0.07 0.6025
Toxoplasma gondii ABC1 family protein 0.0378 0.07 0.7034
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0125 0.0195 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0207 0.0359 0.1771
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0042 0.005
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0113 0.017 0.0205
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.002 0.0087
Echinococcus granulosus Polycystic kidney disease protein 0.0063 0.0071 0.0086
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0062 0.0068 0.1836
Treponema pallidum alginate O-acetylation protein (algI) 0.036 0.0665 1
Loa Loa (eye worm) doublecortin family protein 0.0063 0.0071 0.0086
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0003 0.0003
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0086 0.0118 0.0142
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.036 0.0665 0.0664
Brugia malayi MAP kinase sur-1 0.0114 0.0173 0.0208
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0025 0.0189
Echinococcus multilocularis ecdysone induced protein 78C 0.0102 0.015 0.015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0006 0.0006
Echinococcus granulosus muscleblind protein 0.1718 0.338 0.4074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0102 0.015 0.018
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0086 0.0118 0.0994
Echinococcus multilocularis zinc finger protein 0.0042 0.0029 0.0029
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0062 0.0068 0.0565
Leishmania major trypanothione reductase 0.0051 0.0047 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.036 0.0665 0.3292
Schistosoma mansoni hypothetical protein 0.0063 0.0071 0.0086
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0047 0.0094
Brugia malayi ecdysone receptor 0.0048 0.0042 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.002 0.0087
Mycobacterium leprae Conserved hypothetical protein 0.0044 0.0033 0.0264
Plasmodium falciparum thioredoxin reductase 0.0051 0.0047 0.042
Trichomonas vaginalis set domain proteins, putative 0.1035 0.2013 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0062 0.0068 0.0068
Brugia malayi nuclear receptor NHR-88 0.0048 0.0042 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0026 0.0113
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0086 0.0118 0.0994
Loa Loa (eye worm) latrophilin receptor protein 2 0.0113 0.017 0.0205
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0029 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0099 0.0143 0.0172
Toxoplasma gondii thioredoxin reductase 0.0051 0.0047 0.045
Brugia malayi glutathione reductase 0.0051 0.0047 0.0057
Mycobacterium tuberculosis Conserved protein 0.0378 0.07 0.1463
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0025 0.0182
Echinococcus granulosus mixed lineage leukemia protein mll 0.0049 0.0043 0.0051
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0044 0.0033 0.0264
Schistosoma mansoni cpg binding protein 0.019 0.0325 0.0391
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0102 0.015 0.018
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.002 0.0024
Brugia malayi nuclear receptor NHR-67 0.0048 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.0063 0.0071 0.0086
Trichomonas vaginalis D-aminoacylase, putative 0.0378 0.07 0.3469
Schistosoma mansoni hypothetical protein 0.0633 0.121 0.1458
Brugia malayi MBOAT family protein 0.4178 0.8295 1
Schistosoma mansoni zinc finger protein 0.0048 0.0042 0.005
Schistosoma mansoni hypothetical protein 0.0154 0.0253 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0102 0.015 0.018
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.0054 0.0053 0.0064
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0117 0.0179 0.0369
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0052 0.0049 0.0232
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0034 0.0012 0.0014
Schistosoma mansoni zinc finger protein 0.4178 0.8295 1
Echinococcus granulosus cytochrome P450 2K1 0.0044 0.0033 0.004
Brugia malayi beta-lactamase family protein 0.0378 0.07 0.0844
Loa Loa (eye worm) CXXC zinc finger family protein 0.0178 0.03 0.0362
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0066 0.0523
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.002 0.0263
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0025 0.0205
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0378 0.07 0.6025
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0025 0.0109
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0378 0.07 0.1463
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0085 0.0116 0.0139
Schistosoma mansoni lipoxygenase 0.0251 0.0447 0.0539
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0066 0.0079
Mycobacterium tuberculosis Probable aminotransferase 0.0608 0.1161 0.2428
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0044 0.0033 0.0264
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0003
Brugia malayi Aldehyde dehydrogenase protein 4 0.0029 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0044 0.0033 0.0064
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0074 0.0089
Leishmania major hypothetical protein, conserved 0.036 0.0665 0.5496
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0048 0.0042 0.005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.0248 0.0299
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0044 0.0033 0.0264
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0086 0.0118 0.5
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0102 0.015 0.018
Loa Loa (eye worm) hypothetical protein 0.036 0.0665 0.0801
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0026 0.0113
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.0032 0.0184
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0029 0.0003 0.0002
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0041 0.0191
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0086 0.0118 0.0241
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0064 0.0612
Mycobacterium ulcerans putative regulatory protein 0.0038 0.002 0.0152
Loa Loa (eye worm) hypothetical protein 0.036 0.0665 0.0801
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0113
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0251 0.0447 0.0539
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0102 0.015 0.018
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0062 0.0068 0.568
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.036 0.0665 0.6674
Brugia malayi follicle stimulating hormone receptor 0.1412 0.2768 0.3336
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.013 0.0205 0.0423
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0207 0.0359 0.2974
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0114 0.0173 0.1415
Mycobacterium ulcerans aldehyde dehydrogenase 0.0525 0.0994 0.8565
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0152 0.0248 0.0248
Trypanosoma cruzi PAB1-binding protein , putative 0.0132 0.0208 0.1704
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.014 0.0224 0.2231
Echinococcus multilocularis ornithine aminotransferase 0.0086 0.0118 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0113
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0378 0.07 0.0844
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0044 0.0033 0.0064
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0311 0.0568 0.0684
Echinococcus granulosus dnaJ subfamily B 0.17 0.3344 0.4031
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0608 0.1161 0.2428
Brugia malayi hypothetical protein 0.0048 0.0042 0.005
Echinococcus granulosus mitogen activated protein kinase 3 0.0114 0.0173 0.0208
Loa Loa (eye worm) hypothetical protein 0.0378 0.07 0.0844
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.058 0.1104 0.1331
Brugia malayi MBOAT family protein 0.036 0.0665 0.0801
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0026 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.002 0.0087
Brugia malayi MBOAT family protein 0.036 0.0665 0.0801
Brugia malayi Latrophilin receptor protein 2 0.0113 0.017 0.0205
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0085 0.0116 0.0139
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0026 0.0113
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Schistosoma mansoni hypothetical protein 0.0243 0.0431 0.052
Echinococcus granulosus sterol O acyltransferase 1 0.036 0.0665 0.0801
Echinococcus granulosus importin subunit beta 1 0.0059 0.0064 0.0076
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0207 0.0359 0.0359
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0378 0.07 0.0844
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.058 0.1104 0.1331
Mycobacterium tuberculosis Probable oxidoreductase 0.013 0.0205 0.0423
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0047 0.0057
Plasmodium vivax SET domain protein, putative 0.0134 0.0213 0.2825
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0102 0.015 0.018
Mycobacterium ulcerans hypothetical protein 0.0378 0.07 0.6025
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0029 0.0003 0.0003
Brugia malayi hypothetical protein 0.0132 0.0208 0.025
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0042 0.0205
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.002 0.0019
Loa Loa (eye worm) steroid hormone receptor 0.0102 0.015 0.018
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0086 0.0118 0.0994
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0025 0.0029
Loa Loa (eye worm) hypothetical protein 0.0206 0.0357 0.0429
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0114 0.0173 0.1415
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0102 0.015 0.015
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0469 0.0882 0.1063
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0044 0.0033 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0102 0.015 0.018
Schistosoma mansoni hypothetical protein 0.17 0.3344 0.4031
Brugia malayi hypothetical protein 0.0085 0.0115 0.0138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0102 0.015 0.018
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0029 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0244 0.0432 0.052
Mycobacterium tuberculosis Probable dehydrogenase 0.0117 0.0179 0.0369
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0086 0.0416
Schistosoma mansoni hypothetical protein 0.0338 0.0621 0.0748
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0042 0.005
Toxoplasma gondii hypothetical protein 0.0038 0.002 0.0177
Loa Loa (eye worm) hypothetical protein 0.0063 0.0071 0.0086
Echinococcus granulosus FTZ F1 alpha 0.0102 0.015 0.018
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.002 0.0145
Schistosoma mansoni steroid hormone receptor ad4bp 0.0102 0.015 0.018
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0029 0.0003 0.0023
Brugia malayi conserved hypotetical protein 0.0048 0.0042 0.005
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0085 0.0116 0.0115
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0154 0.0253 0.0305
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0044 0.0033 0.0277
Brugia malayi hypothetical protein 0.0063 0.0071 0.0086
Loa Loa (eye worm) hypothetical protein 0.0099 0.0143 0.0172
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0029 0.0003 0.0003
Brugia malayi Glycosyl hydrolases family 31 protein 0.017 0.0284 0.0342
Trypanosoma cruzi hypothetical protein, conserved 0.0378 0.07 0.5792
Loa Loa (eye worm) hypothetical protein 0.0388 0.072 0.0868
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0044 0.0033 0.0064
Schistosoma mansoni hypothetical protein 0.0113 0.017 0.0205
Schistosoma mansoni survival motor neuron protein 0.0154 0.0253 0.0305
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0207 0.0359 0.1771
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0025 0.0182
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0102 0.015 0.015
Trypanosoma brucei unspecified product 0.004 0.0025 0.0205
Mycobacterium ulcerans esterase/lipase LipP 0.0378 0.07 0.6025
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0102 0.015 0.018
Loa Loa (eye worm) hypothetical protein 0.0207 0.0359 0.0432
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0044 0.0033 0.0064
Brugia malayi orphan nuclear receptor NR2E1 0.0048 0.0042 0.005
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0064 0.0063
Brugia malayi nuclear hormone receptor family member odr-7 0.0048 0.0042 0.005
Mycobacterium ulcerans beta-lactamase 0.0378 0.07 0.6025
Echinococcus granulosus neuropeptide s receptor 0.103 0.2003 0.2414
Onchocerca volvulus 0.0178 0.03 0.149
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.036 0.0665 0.0801
Brugia malayi acetyltransferase, GNAT family protein 0.0469 0.0882 0.1063
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0041 0.0191
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0029 0.0003 0.0003
Echinococcus granulosus fetal alzheimer antigen falz 0.0034 0.0012 0.0014
Echinococcus granulosus zinc finger protein 0.0042 0.0029 0.0034
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0029 0.0003 0.0023
Entamoeba histolytica hypothetical protein 0.0311 0.0568 0.8535
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0066 0.0079
Echinococcus granulosus Aminotransferase class III 0.0086 0.0118 0.0142
Onchocerca volvulus Protein ultraspiracle homolog 0.0102 0.015 0.0743
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0032 0.0245
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.006 0.0065 0.0077
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0025 0.0046
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0044 0.0033 0.0064
Echinococcus multilocularis survival motor neuron protein 1 0.0756 0.1456 0.1456
Echinococcus granulosus o acyltransferase membrane bound domain 0.036 0.0665 0.0801
Plasmodium falciparum diacylglycerol O-acyltransferase 0.036 0.0665 1
Brugia malayi steroid hormone receptor 0.0102 0.015 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205
Entamoeba histolytica hypothetical protein 0.0311 0.0568 0.8535
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0525 0.0994 0.8235
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0173 0.0848
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0021 0.0089
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0029 0.0003 0.0023
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0062 0.0068 0.0082
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0207 0.0359 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0378 0.07 0.0844
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0102 0.015 0.0743
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0102 0.015 0.015
Schistosoma mansoni nuclear receptor 0.0048 0.0042 0.005
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0066 0.0065
Mycobacterium ulcerans hypothetical protein 0.0608 0.1161 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0102 0.015 0.018
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0029 0.0003 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.002 0.0145
Onchocerca volvulus 0.0102 0.015 0.0743
Loa Loa (eye worm) hypothetical protein 0.0054 0.0053 0.0063
Brugia malayi nuclear hormone receptor 0.0102 0.015 0.018
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0173 0.0208
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0029 0.0003 0.0023
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.0071 0.0086
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0086 0.0118 1
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0044 0.0033 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0102 0.015 0.018
Echinococcus multilocularis dnaJ subfamily B 0.17 0.3344 0.3343
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.036 0.0665 0.0664
Brugia malayi Calcitonin receptor-like protein seb-1 0.0356 0.0656 0.0791
Toxoplasma gondii hypothetical protein 0.036 0.0665 0.6674
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0086 0.0118 0.0241
Echinococcus granulosus microtubule associated protein 2 0.1541 0.3025 0.3646
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0044 0.0033 0.0264
Loa Loa (eye worm) inositol-1 0.0038 0.0021 0.0025
Brugia malayi F/Y-rich N-terminus family protein 0.0061 0.0067 0.0081
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.4178 0.8295 0.8295
Loa Loa (eye worm) hypothetical protein 0.0054 0.0053 0.0064
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0025 0.0029
Leishmania major DNA polymerase eta, putative 0.004 0.0025 0.0182
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0085 0.0116 0.056
Brugia malayi Pre-SET motif family protein 0.091 0.1763 0.2125
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0258 0.0461 0.0555
Schistosoma mansoni alpha glucosidase 0.0038 0.002 0.0024
Brugia malayi hypothetical protein 0.0054 0.0053 0.0064
Schistosoma mansoni alpha-glucosidase 0.0146 0.0237 0.0285
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0052 0.0049 0.0059
Entamoeba histolytica hypothetical protein 0.0311 0.0568 0.8535
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0251 0.0447 0.0447
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0102 0.015 0.018
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0086 0.0118 0.0994
Schistosoma mansoni bromodomain containing protein 0.0087 0.012 0.0144
Leishmania major hypothetical protein, conserved 0.0378 0.07 0.5792
Onchocerca volvulus 0.0048 0.0042 0.0205
Onchocerca volvulus Huntingtin homolog 0.0388 0.072 0.3576
Loa Loa (eye worm) acetyltransferase 0.0469 0.0882 0.1063
Brugia malayi aldehyde dehydrogenase 0.0029 0.0003 0.0003
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0299 0.0542 0.448
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0089 0.0123 0.0994
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0062 0.0068 0.0742
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.002 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0044 0.0033 0.0064
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0089 0.0123 0.1015
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0299 0.0542 0.448
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.036 0.0665 0.0664
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0086 0.0118 0.0994
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.091 0.1763 0.2125
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.002 0.0263
Brugia malayi hypothetical protein 0.0756 0.1456 0.1755
Trichomonas vaginalis bromodomain-containing protein, putative 0.014 0.0224 0.11
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0086 0.0118 0.116
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0042 0.005
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0086 0.0118 0.0994
Loa Loa (eye worm) bromodomain containing protein 0.003 0.0005 0.0005
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0038 0.002 0.0037
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.0071 0.0071
Echinococcus granulosus ubiquitin specific protease 41 0.0207 0.0359 0.0432
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0025 0.0024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0049 0.0043 0.0051
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.036 0.0665 0.0664
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0074 0.0089
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0113 0.017 0.0205
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.0071 0.0086
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0044 0.0033 0.0264
Mycobacterium ulcerans aldehyde dehydrogenase 0.0525 0.0994 0.8565
Onchocerca volvulus 0.1035 0.2013 1
Trichomonas vaginalis D-aminoacylase, putative 0.0378 0.07 0.3469
Echinococcus multilocularis cpg binding protein 0.019 0.0325 0.0324
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0025 0.0046
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0044 0.0033 0.0254
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0134 0.0213 0.0256
Trypanosoma brucei protein kinase, putative 0.0114 0.0173 0.1435
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.036 0.0665 1
Loa Loa (eye worm) hypothetical protein 0.036 0.0665 0.0801
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.013 0.0205 0.0423
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0207 0.0359 0.2957
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0048 0.0042 0.005
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0003 0.0003
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0062 0.0068 0.0137
Schistosoma mansoni polycystin 1-related 0.0063 0.0071 0.0086
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0356 0.0656 0.0791
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0042 0.005
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0066 0.0079
Giardia lamblia Histone acetyltransferase GCN5 0.0126 0.0196 0.5433
Loa Loa (eye worm) hypothetical protein 0.0206 0.0358 0.0431
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.058 0.1104 0.1331
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0356 0.0656 0.0791
Brugia malayi RNA binding protein 0.0065 0.0074 0.0089
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.036 0.0665 1
Schistosoma mansoni cpg binding protein 0.0178 0.03 0.0362
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0029 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205
Leishmania major glycerol uptake protein, putative 0.036 0.0665 0.5496
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Echinococcus multilocularis neuropeptide s receptor 0.103 0.2003 0.2002
Loa Loa (eye worm) hypothetical protein 0.1718 0.338 0.4074
Trypanosoma brucei glycerol uptake protein, putative 0.036 0.0665 0.5506
Trichomonas vaginalis ap endonuclease, putative 0.0062 0.0068 0.0325
Mycobacterium ulcerans aldehyde dehydrogenase 0.0525 0.0994 0.8565
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0074 0.0074
Trichomonas vaginalis transmembrane protein nessy, putative 0.036 0.0665 0.3292
Loa Loa (eye worm) MBOAT family protein 0.036 0.0665 0.0801
Schistosoma mansoni sterol O-acyltransferase 1 0.036 0.0665 0.0801
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0085 0.0116 0.056
Brugia malayi Doublecortin family protein 0.0063 0.0071 0.0086
Brugia malayi MBOAT family protein 0.036 0.0665 0.0801
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0049 0.0043 0.0043
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0003 0.0003
Loa Loa (eye worm) DR-78 0.0048 0.0042 0.005
Schistosoma mansoni hypothetical protein 0.0059 0.0063 0.0076
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0025 0.0109
Brugia malayi exodeoxyribonuclease III family protein 0.0062 0.0068 0.0082
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0054 0.0053 0.0064
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0041 0.0318
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0086 0.0416
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0044 0.0033 0.0264
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0025 0.0182
Brugia malayi Bromodomain containing protein 0.01 0.0144 0.0173
Echinococcus multilocularis Aminotransferase class III 0.0086 0.0118 0.0118
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0102 0.015 0.015
Loa Loa (eye worm) hhat protein 0.036 0.0665 0.0801
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0021 0.0149
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0066 0.0132
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0042 0.005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.058 0.1104 0.1331
Plasmodium falciparum LCCL domain-containing protein 0.0063 0.0071 0.0792
Brugia malayi MBOAT family protein 0.036 0.0665 0.0801
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.002 0.0087
Echinococcus granulosus dna polymerase eta 0.004 0.0025 0.0029
Giardia lamblia Kinase, CMGC MAPK 0.0114 0.0173 0.4786
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0134 0.0213 0.2115
Brugia malayi tailless protein 0.0048 0.0042 0.005
Loa Loa (eye worm) MBOAT family protein 0.036 0.0665 0.0801
Echinococcus granulosus ecdysone induced protein 78C 0.0102 0.015 0.018
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0066 0.0544
Loa Loa (eye worm) hypothetical protein 0.0066 0.0077 0.0092
Loa Loa (eye worm) hypothetical protein 0.0102 0.015 0.018
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0044 0.0033 0.0064
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0025 0.0029
Schistosoma mansoni ran 0.0044 0.0032 0.0039
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0029 0.0003 0.0023
Onchocerca volvulus 0.0378 0.07 0.3477
Entamoeba histolytica Ran family GTPase 0.0044 0.0032 0.0445
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0044 0.0033 0.0064
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0631 0.1207 1
Leishmania major hypothetical protein, conserved 0.0132 0.0208 0.1704
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0025 0.0029
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0025 0.0182
Trypanosoma brucei glucosidase, putative 0.0038 0.002 0.0168
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0113 0.017 0.017
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0021 0.0149
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0025 0.0205
Entamoeba histolytica vacuolar protein sorting 26 0.036 0.0665 1
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.036 0.0665 0.0801
Leishmania major glycerol uptake protein, putative 0.036 0.0665 0.5496
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.036 0.0665 0.0664
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0089 0.0123 0.0994
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0034 0.0012 0.0012
Plasmodium falciparum ornithine aminotransferase 0.0086 0.0118 0.1513
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0053 0.0064
Loa Loa (eye worm) cytochrome P450 family protein 0.0174 0.0292 0.0352
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.002 0.0087
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.036 0.0665 0.0801
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0044 0.0033 0.0264
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0025 0.0029
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0113
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0044 0.0033 0.0264
Entamoeba histolytica hypothetical protein 0.036 0.0665 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0044 0.0033 0.0264
Schistosoma mansoni nuclear receptor 0.0048 0.0042 0.005
Echinococcus multilocularis dna polymerase kappa 0.004 0.0025 0.0024
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0258 0.0461 0.0461
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.0032 0.0268
Plasmodium vivax glutathione reductase, putative 0.0051 0.0047 0.0398
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.058 0.1104 0.1331
Echinococcus multilocularis FTZ F1 alpha 0.0102 0.015 0.015
Echinococcus granulosus lysophospholipid acyltransferase 7 0.036 0.0665 0.0801
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.058 0.1104 0.1104
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.0173 0.1415
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0089 0.0123 0.0994
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0134 0.0213 0.0212
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0173 0.0848
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0207 0.0359 0.0432
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0134 0.0213 0.0256
Loa Loa (eye worm) aldehyde dehydrogenase 0.0029 0.0003 0.0003
Trypanosoma cruzi glycerol uptake protein, putative 0.036 0.0665 0.5496
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0044 0.0033 0.0264
Loa Loa (eye worm) hypothetical protein 0.0243 0.0431 0.052
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0102 0.015 0.018
Mycobacterium tuberculosis Conserved protein 0.0378 0.07 0.1463
Treponema pallidum exodeoxyribonuclease (exoA) 0.0062 0.0068 0.0988
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0054 0.0053 0.0053
Echinococcus multilocularis 0.0044 0.0033 0.0033
Onchocerca volvulus 0.0134 0.0213 0.1054
Entamoeba histolytica acetyltransferase, GNAT family 0.0126 0.0196 0.2923
Echinococcus multilocularis tumor protein p63 0.141 0.2764 0.2763
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0086 0.0118 0.0994
Trypanosoma brucei trypanothione reductase 0.0051 0.0047 0.0393
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0052 0.0049 0.0232
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0044 0.0033 0.0064
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0048 0.0042 0.005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0085 0.0116 0.056
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.0032 0.0039
Brugia malayi Cytochrome P450 family protein 0.0064 0.0074 0.0089
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0102 0.015 0.018
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0044 0.0033 0.0064
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0021 0.002
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0114 0.0173 0.0208
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0048 0.0042 0.005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0333 0.061 0.1273
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0086 0.0118 0.0241
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0054 0.0053 0.0064
Giardia lamblia DINP protein human, muc B family 0.004 0.0025 0.0614
Echinococcus multilocularis microtubule associated protein 2 0.1541 0.3025 0.3025
Trichomonas vaginalis penicillin-binding protein, putative 0.0378 0.07 0.3469
Mycobacterium ulcerans hypothetical protein 0.0333 0.061 0.5242
Plasmodium falciparum glutathione reductase 0.0051 0.0047 0.042
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.013 0.0205 0.1744
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0085 0.0116 0.0957
Schistosoma mansoni loxhd1 0.0063 0.0071 0.0086
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0608 0.1161 0.5758
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0047 0.0057
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0378 0.07 0.1463
Loa Loa (eye worm) hypothetical protein 0.0102 0.015 0.018
Echinococcus granulosus cpg binding protein 0.019 0.0325 0.0391
Mycobacterium tuberculosis Probable esterase LipL 0.0378 0.07 0.1463
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.036 0.0665 0.0664
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0113 0.017 0.0205
Loa Loa (eye worm) hypothetical protein 0.0054 0.0053 0.0064
Mycobacterium tuberculosis Probable reductase 0.0117 0.0179 0.0369
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0102 0.015 0.018
Mycobacterium tuberculosis Conserved protein 0.0378 0.07 0.1463
Echinococcus granulosus histone acetyltransferase KAT2B 0.0453 0.0851 0.1025
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0224 0.027
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0311 0.0568 0.0567
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0029 0.0003 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.058 0.1104 0.1331
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0085 0.0116 0.0936
Brugia malayi nuclear receptor RXR 0.0054 0.0053 0.0064
Trypanosoma brucei PAB1-binding protein , putative 0.0132 0.0208 0.1724
Onchocerca volvulus 0.0206 0.0358 0.1775
Schistosoma mansoni ran 0.0044 0.0032 0.0039
Schistosoma mansoni thyroid hormone receptor 0.0102 0.015 0.018
Schistosoma mansoni hypothetical protein 0.0029 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0378 0.07 0.0844
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0013 0.0086
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.002 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0113
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0062 0.0068 0.0565
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0074 0.0089
Schistosoma mansoni hypothetical protein 0.0113 0.017 0.0205
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0085 0.0116 0.056
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0062 0.0068 0.0988
Echinococcus multilocularis ubiquitin specific protease 41 0.0207 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0102 0.015 0.018
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0525 0.0994 0.0994
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0044 0.0033 0.0064
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0102 0.015 0.018
Echinococcus granulosus neuropeptide receptor A26 0.103 0.2003 0.2414
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0044 0.0033 0.0064
Brugia malayi Muscleblind-like protein 0.1718 0.338 0.4074
Echinococcus granulosus tumor protein p63 0.141 0.2764 0.3331
Trypanosoma cruzi glycerol uptake protein, putative 0.036 0.0665 0.5496
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0044 0.0033 0.0264
Echinococcus granulosus o acyltransferase membrane bound domain 0.036 0.0665 0.0801
Brugia malayi beta-lactamase family protein 0.0378 0.07 0.0844
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.015 0.018
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0258 0.0461 0.0555
Loa Loa (eye worm) hypothetical protein 0.0388 0.072 0.0868
Schistosoma mansoni hypothetical protein 0.0044 0.0033 0.004
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0608 0.1161 1
Schistosoma mansoni cellular tumor antigen P53 0.0206 0.0358 0.0431
Toxoplasma gondii aldehyde dehydrogenase 0.0525 0.0994 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0033 0.0254
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0102 0.015 0.015
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0117 0.0179 0.0369
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.036 0.0665 0.0801
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0074 0.0089
Loa Loa (eye worm) CYP4Cod1 0.0064 0.0074 0.0089
Loa Loa (eye worm) hypothetical protein 0.0378 0.07 0.0844
Loa Loa (eye worm) hypothetical protein 0.0378 0.07 0.0844
Trypanosoma cruzi hypothetical protein, conserved 0.0378 0.07 0.5792
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0085 0.0116 0.0936
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0021 0.0271
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0074 0.0089
Echinococcus multilocularis GPCR, family 2 0.0113 0.017 0.017
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0021 0.1558
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0026 0.0113
Trichomonas vaginalis D-aminoacylase, putative 0.0378 0.07 0.3469
Brugia malayi Nuclear hormone receptor-like 1 0.0102 0.015 0.018
Schistosoma mansoni aldehyde dehydrogenase 0.0525 0.0994 0.1199
Trichomonas vaginalis helicase, putative 0.004 0.0026 0.0113
Trypanosoma brucei glycerol uptake protein, putative 0.036 0.0665 0.5506
Loa Loa (eye worm) hypothetical protein 0.0756 0.1456 0.1755
Brugia malayi nuclear hormone receptor 0.0048 0.0042 0.005
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0064 0.0074 0.0613
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0114 0.0173 0.1415
Brugia malayi hypothetical protein 0.0048 0.0042 0.005
Brugia malayi nuclear receptor RXR 0.0048 0.0042 0.005
Schistosoma mansoni importin beta-1 0.0059 0.0064 0.0076
Trichomonas vaginalis porcupine, putative 0.036 0.0665 0.3292
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0025 0.0182
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0042 0.0041
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.0032 0.0032
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.036 0.0665 1
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0021 0.0025
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0064 0.0527
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.006 0.0065 0.0064
Schistosoma mansoni cytochrome P450 0.0044 0.0033 0.004
Brugia malayi Bromodomain containing protein 0.0051 0.0048 0.0057
Brugia malayi Inositol-1 0.0038 0.0021 0.0025
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0102 0.015 0.018
Schistosoma mansoni DNA polymerase eta 0.004 0.0025 0.0029
Onchocerca volvulus 0.0378 0.07 0.3477
Entamoeba histolytica hypothetical protein, conserved 0.036 0.0665 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0207 0.0359 0.2957
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0111
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.0032 0.0039
Mycobacterium tuberculosis Probable lipase LipE 0.0378 0.07 0.1463
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0044 0.0033 0.0264
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0044 0.0033 0.0264
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.0193 0.0233
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0042 0.005
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0029 0.0003 0.0003
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.4178 0.8295 1
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0044 0.0033 0.0064
Entamoeba histolytica hypothetical protein 0.0311 0.0568 0.8535
Brugia malayi Cytochrome P450 family protein 0.0064 0.0074 0.0089
Schistosoma mansoni transcription factor LCR-F1 0.0311 0.0568 0.0684
Mycobacterium leprae Probable lipase LipE 0.0378 0.07 0.6025
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0021 0.0089
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0102 0.015 0.015
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0062 0.0068 0.0082
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0029 0.0003 0.0002
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0038 0.002 0.0152
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0102 0.015 0.018
Echinococcus multilocularis zinc finger protein 0.3818 0.7575 0.7575
Onchocerca volvulus 0.0063 0.0071 0.0353
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0207 0.0359 0.538
Echinococcus multilocularis muscleblind protein 1 0.1718 0.338 0.3379
Schistosoma mansoni rab6-interacting 0.0063 0.0071 0.0086
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0525 0.0994 0.1199
Brugia malayi MH2 domain containing protein 0.0124 0.0193 0.0233
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0021 0.0089
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.014 0.0224 0.11
Loa Loa (eye worm) beta-lactamase 0.0378 0.07 0.0844
Mycobacterium leprae conserved hypothetical protein 0.0378 0.07 0.6025
Plasmodium falciparum ataxin-2 like protein, putative 0.0132 0.0208 0.2912
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0062 0.0068 0.0703
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0102 0.015 0.018
Brugia malayi beta-lactamase 0.0378 0.07 0.0844
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0382 0.0708 0.0853
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0113
Onchocerca volvulus Bile acid receptor homolog 0.0102 0.015 0.0743
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0207 0.0359 0.2957
Echinococcus granulosus thyroid hormone receptor alpha 0.0048 0.0042 0.005
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0469 0.0882 0.0882
Loa Loa (eye worm) hypothetical protein 0.0102 0.015 0.018
Echinococcus granulosus ornithine aminotransferase 0.0086 0.0118 0.0142
Loa Loa (eye worm) nuclear receptor NHR-67 0.0048 0.0042 0.005
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0114 0.0173 0.1415
Loa Loa (eye worm) hypothetical protein 0.0052 0.0049 0.0059
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0102 0.015 0.018
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0173 0.0848
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0029 0.0003 0.0003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0108 0.0161 0.1316
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0207 0.0359 0.0432
Onchocerca volvulus Huntingtin homolog 0.0388 0.072 0.3576
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0102 0.015 0.018
Loa Loa (eye worm) hypothetical protein 0.0378 0.07 0.0844
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0631 0.1207 1
Mycobacterium ulcerans putative regulatory protein 0.0038 0.002 0.0152
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0021 0.0149
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0053 0.0064
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0041 0.0191
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.036 0.0665 0.9475
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0113 0.017 0.017
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0378 0.07 0.0844
Loa Loa (eye worm) hypothetical protein 0.0113 0.017 0.0205
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0044 0.0033 0.0064
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0032 0.0245
Loa Loa (eye worm) hypothetical protein 0.004 0.0025 0.003
Echinococcus granulosus zinc finger protein 0.3818 0.7575 0.9133
Leishmania major glycerol uptake protein, putative 0.036 0.0665 0.5496
Echinococcus multilocularis ornithine aminotransferase 0.0086 0.0118 0.0118
Brugia malayi Hhat protein 0.036 0.0665 0.0801
Brugia malayi hypothetical protein 0.0054 0.0053 0.0064
Trypanosoma brucei cytochrome P450, putative 0.0064 0.0074 0.0612
Trypanosoma cruzi GUP1, putative 0.036 0.0665 0.5496
Toxoplasma gondii hypothetical protein 0.0102 0.0149 0.147
Brugia malayi hypothetical protein 0.0063 0.0071 0.0086
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0102 0.015 0.018
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0062 0.0068 0.0543
Loa Loa (eye worm) histone methyltransferase 0.006 0.0065 0.0077
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0044 0.0033 0.0264
Echinococcus multilocularis sterol O acyltransferase 1 0.036 0.0665 0.0664
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1412 0.2768 0.3336
Schistosoma mansoni zinc finger protein 0.0042 0.0029 0.0034
Trichomonas vaginalis esterase, putative 0.0378 0.07 0.3469
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0074 0.0089
Loa Loa (eye worm) RNA binding protein 0.0065 0.0074 0.0089
Mycobacterium leprae conserved hypothetical protein 0.0038 0.002 0.0152
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0033 0.0254
Echinococcus multilocularis geminin 0.0338 0.0621 0.062
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0025 0.0189
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205
Brugia malayi cytochrome P450 0.0044 0.0033 0.004
Schistosoma mansoni hypothetical protein 0.036 0.0665 0.0801
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.014 0.0224 0.2231
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0074 0.0089
Onchocerca volvulus 0.0048 0.0042 0.0205
Brugia malayi diacylglycerol acyltransferase 0.036 0.0665 0.0801
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0114 0.0173 0.1435
Loa Loa (eye worm) hypothetical protein 0.0054 0.0053 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0102 0.015 0.018
Plasmodium falciparum ataxin-2 like protein, putative 0.0132 0.0208 0.2912
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0059 0.0063 0.0063
Loa Loa (eye worm) diacylglycerol acyltransferase 0.036 0.0665 0.0801
Echinococcus granulosus mitogen activated protein kinase 0.0114 0.0173 0.0208
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0633 0.121 0.1458
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0207 0.0359 0.0432
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0021 0.0181
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0117 0.0179 0.0369
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Schistosoma mansoni aldehyde dehydrogenase 0.0525 0.0994 0.1199
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.002 0.0145
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0044 0.0033 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0116 0.056
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.0152 0.0248 0.0299
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0044 0.0033 0.0254
Brugia malayi Cytochrome P450 family protein 0.0044 0.0033 0.004
Echinococcus multilocularis RUN 0.0063 0.0071 0.0071
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0044 0.0033 0.0264
Schistosoma mansoni coup transcription factor 0.0102 0.015 0.018
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.058 0.1104 0.1331
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0026 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0086 0.0416
Plasmodium vivax multidomain scavenger receptor, putative 0.0063 0.0071 0.075
Trypanosoma cruzi cytochrome P450, putative 0.0064 0.0074 0.0589
Echinococcus multilocularis beta LACTamase domain containing family member 0.0378 0.07 0.07
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.002 0.0176
Leishmania major importin beta-1 subunit, putative 0.0048 0.0041 0.0318
Schistosoma mansoni eyes absent homolog 0.0099 0.0143 0.0172
Brugia malayi Pre-SET motif family protein 0.0134 0.0213 0.0256
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.036 0.0665 0.0801
Plasmodium falciparum histone acetyltransferase GCN5 0.0126 0.0196 0.273
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0059 0.0063 0.0076
Loa Loa (eye worm) nuclear hormone receptor 0.0048 0.0042 0.005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0066 0.0544
Brugia malayi latrophilin 2 splice variant baaae 0.0243 0.0431 0.052
Trichomonas vaginalis conserved hypothetical protein 0.036 0.0665 0.3292
Leishmania major cytochrome p450-like protein 0.0044 0.0033 0.0254
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.002 0.0087
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0608 0.1161 1
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0173 0.0848
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Trichomonas vaginalis ran, putative 0.0044 0.0032 0.0146
Schistosoma mansoni nuclear hormone receptor 0.0102 0.015 0.018
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Echinococcus granulosus lysosomal alpha glucosidase 0.017 0.0284 0.0342
Brugia malayi hypothetical protein 0.0311 0.0568 0.0684
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0284 0.0284
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0026 0.0113
Brugia malayi RNA, U transporter 1 0.0169 0.0282 0.034
Schistosoma mansoni lipoxygenase 0.0137 0.022 0.0265
Loa Loa (eye worm) cytochrome P450 0.0044 0.0033 0.004
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0113
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.036 0.0665 0.6674
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0003 0.0003
Brugia malayi PHD-finger family protein 0.0047 0.004 0.0048
Loa Loa (eye worm) hypothetical protein 0.0356 0.0656 0.0791
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0117 0.0179 0.1519
Echinococcus granulosus geminin 0.0338 0.0621 0.0748
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0085 0.0116 0.056
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0102 0.015 0.018
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0048 0.004 0.0186
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.005
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0052 0.0049 0.0059
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.002 0.0087
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0003 0.0003
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0207 0.0359 0.0432
Loa Loa (eye worm) hypothetical protein 0.0102 0.015 0.018
Loa Loa (eye worm) glutathione reductase 0.0051 0.0047 0.0057
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0085 0.0116 0.056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0102 0.015 0.018
Leishmania major cytochrome p450-like protein 0.0064 0.0074 0.0589
Trichomonas vaginalis conserved hypothetical protein 0.036 0.0665 0.3292
Echinococcus granulosus dna polymerase kappa 0.004 0.0025 0.0029
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0042 0.0205
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0525 0.0994 0.208
Toxoplasma gondii GAF domain-containing protein 0.0038 0.002 0.0177
Plasmodium vivax hypothetical protein, conserved 0.0378 0.07 1
Trypanosoma cruzi GUP1, putative 0.036 0.0665 0.5496
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0021 0.0172
Schistosoma mansoni cpg binding protein 0.019 0.0325 0.0391
Loa Loa (eye worm) hypothetical protein 0.1718 0.338 0.4074
Echinococcus multilocularis mitogen activated protein kinase 0.0114 0.0173 0.0173
Schistosoma mansoni hypothetical protein 0.0338 0.0621 0.0748
Loa Loa (eye worm) hypothetical protein 0.036 0.0665 0.0801
Toxoplasma gondii LsmAD domain-containing protein 0.0132 0.0208 0.2069
Echinococcus granulosus RUN 0.0063 0.0071 0.0086
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0054 0.0053 0.0064
Brugia malayi CXXC zinc finger family protein 0.0178 0.03 0.0362
Toxoplasma gondii hypothetical protein 0.0038 0.002 0.0177
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0114 0.0173 0.1719
Echinococcus granulosus tar DNA binding protein 0.0065 0.0074 0.0089
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.0193 0.0233
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0102 0.015 0.018
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0047 0.0371
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.002 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0026 0.0113
Loa Loa (eye worm) hypothetical protein 0.0054 0.0053 0.0064
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.036 0.0665 0.0664
Onchocerca volvulus 0.0154 0.0253 0.1256
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.0032 0.0174
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0062 0.0068 0.0543
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0038 0.002 0.0037
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0042 0.0041
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0085 0.0116 0.0957
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0049 0.0043 0.0051
Mycobacterium ulcerans acetylornithine aminotransferase 0.0086 0.0118 0.0994
Schistosoma mansoni nuclear receptor nhr-48 0.0048 0.0042 0.005
Onchocerca volvulus 0.0378 0.07 0.3477
Schistosoma mansoni ap endonuclease 0.0062 0.0068 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0102 0.015 0.018
Mycobacterium tuberculosis Probable hydrolase 0.0378 0.07 0.1463
Echinococcus multilocularis snurportin 1 0.0633 0.121 0.121
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0086 0.0118 0.0241
Echinococcus granulosus membrane bound acyltransferase:hhat 0.036 0.0665 0.0801
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0047 0.0398
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.015 0.018
Echinococcus granulosus beta LACTamase domain containing family member 0.0378 0.07 0.0844
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.002 0.0024
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0048 0.0042 0.0041
Brugia malayi hypothetical protein 0.0099 0.0143 0.0172
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0042 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.002 0.0087
Loa Loa (eye worm) hypothetical protein 0.0378 0.07 0.0844
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0025 0.0205

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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