Detailed information for compound 797029

Basic information

Technical information
  • TDR Targets ID: 797029
  • Name: 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphen yl)amino]-2-oxoethyl]triazole-4-carboxamide
  • MW: 408.454 | Formula: C21H24N6O3
  • H donors: 3 H acceptors: 4 LogP: 3.2 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccccc1NC(=O)c1nnn(c1N)CC(=O)Nc1ccccc1CC
  • InChi: 1S/C21H24N6O3/c1-3-14-9-5-6-10-15(14)23-18(28)13-27-20(22)19(25-26-27)21(29)24-16-11-7-8-12-17(16)30-4-2/h5-12H,3-4,13,22H2,1-2H3,(H,23,28)(H,24,29)
  • InChiKey: VEQSKMNNYWAETN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphenyl)amino]-2-oxo-ethyl]triazole-4-carboxamide
  • 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphenyl)amino]-2-oxoethyl]-4-triazolecarboxamide
  • 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphenyl)amino]-2-keto-ethyl]triazole-4-carboxamide
  • 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphenyl)amino]-2-oxo-ethyl]-1,2,3-triazole-4-carboxamide
  • NCGC00108149-01
  • C368-0448

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens ubiquitin specific peptidase 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0137 0.4594
Schistosoma mansoni biogenic amine (5HT) receptor 0.0066 0.0081 0.0796
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Schistosoma mansoni opsin-like receptor 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0022
Brugia malayi DKFZp564C0469 protein 0.0031 0.003 0.0142
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0066 0.0081 0.0161
Mycobacterium ulcerans oxidoreductase 0.0016 0.0008 0.0008
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Echinococcus multilocularis serotonin receptor 0.0066 0.0081 0.0161
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0063 0.0076 0.0151
Brugia malayi Pax transcription activation domain interacting protein 0.0031 0.003 0.0142
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi protein C24B5.3 0.0013 0.0004 0.002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0016 0.0008 0.0008
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0063 0.0076 0.0358
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0016 0.053
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.0281 0.1323
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0023 0.054
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0016 0.0263
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0137 0.0645
Schistosoma mansoni hypothetical protein 0.0066 0.0081 0.0796
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0013 0.0031
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0033 0.0034 0.0907
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0021 0.0016 0.006
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0022 0.0021
Mycobacterium ulcerans short chain dehydrogenase 0.0301 0.042 0.042
Onchocerca volvulus 0.0066 0.0081 0.1116
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0028 0.0027 0.0065
Schistosoma mansoni carbonyl reductase 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.011
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796
Echinococcus multilocularis protein dispatched 1 0.0103 0.0134 0.0273
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Onchocerca volvulus 0.0066 0.0081 0.1116
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0016 0.0011
Schistosoma mansoni topbp1 0.0031 0.003 0.0269
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.0281 0.1323
Brugia malayi Melatonin receptor type 1A 0.0066 0.0081 0.038
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0013 0.0004 0.0004
Loa Loa (eye worm) neuropeptide F receptor 0.0066 0.0081 0.038
Echinococcus granulosus lamin 0.0027 0.0025 0.0071
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni hypothetical protein 0.0112 0.0147 0.1483
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0033 0.0034 0.0062
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0029 0.0028 0.0111
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0016 0.0815
Schistosoma mansoni transcription factor LCR-F1 0.0112 0.0147 0.1483
Brugia malayi hypothetical protein 0.0033 0.0034 0.0158
Brugia malayi hypothetical protein 0.002 0.0014 0.0066
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi Cation transporter family protein 0.0063 0.0076 0.0358
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Echinococcus granulosus hypothetical protein 0.0016 0.0008 0.0014
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0008 0.0058
Brugia malayi G protein-coupled receptor F59B2.13 0.0066 0.0081 0.038
Loa Loa (eye worm) dehydrogenase 0.0016 0.0008 0.0039
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0023 0.0023
Schistosoma mansoni cpg binding protein 0.0032 0.0032 0.0287
Schistosoma mansoni myosin xvIII 0.0066 0.0081 0.0796
Mycobacterium ulcerans oxidoreductase 0.0016 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0031 0.003 0.0022
Echinococcus granulosus replication factor c subunit 1 0.0031 0.003 0.0089
Schistosoma mansoni lamin 0.0027 0.0025 0.0215
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0035 0.0143
Schistosoma mansoni neurotransmitter gated ion channel 0.0034 0.0034 0.0314
Echinococcus granulosus tm gpcr rhodopsin 0.2032 0.2915 1
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Onchocerca volvulus 0.0016 0.0008 0.0058
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0079 0.0158
Loa Loa (eye worm) hypothetical protein 0.0759 0.108 0.5078
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Echinococcus granulosus tm gpcr rhodopsin 0.0066 0.0081 0.0263
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.0322 0.1092
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0033 0.0034 0.2052
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.0137 0.0712
Brugia malayi AKH receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0016 0.0008 0.0019
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0019
Onchocerca volvulus 0.0016 0.0008 0.0058
Brugia malayi Niemann-Pick C1 protein precursor 0.021 0.0289 0.1359
Loa Loa (eye worm) cytochrome P450 0.0013 0.0004 0.002
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0016 0.0008 0.0019
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Brugia malayi hypothetical protein 0.0489 0.0691 0.325
Echinococcus granulosus peptide allatostatin:somatostatin 0.0066 0.0081 0.0263
Echinococcus multilocularis neuropeptide receptor 0.0066 0.0081 0.0161
Onchocerca volvulus 0.0074 0.0093 0.129
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0076 0.0358
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0016 0.0008 0.0058
Echinococcus multilocularis G protein coupled receptor 139 0.0066 0.0081 0.0161
Schistosoma mansoni hypothetical protein 0.0019 0.0013 0.0095
Echinococcus multilocularis L aminoadipate semialdehyde 0.0074 0.0093 0.0186
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Echinococcus granulosus G protein coupled receptor 139 0.0066 0.0081 0.0263
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0016 0.0008 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Brugia malayi Serotonin receptor 0.0066 0.0081 0.038
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0028 0.0111
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0033 0.0034 0.0907
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0029 0.0138
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0063 0.0076 0.0358
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0034 0.0034 0.0162
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.0137 0.0457
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0029 0.0028 0.0111
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0027 0.1568
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0012 0.0008
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Mycobacterium ulcerans dehydrogenase/reductase 0.0016 0.0008 0.0008
Echinococcus multilocularis fmrfamide receptor 0.0066 0.0081 0.0161
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Mycobacterium ulcerans transferase 0.0033 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus granulosus hypothetical protein 0.0066 0.0081 0.0263
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0034 0.0035 0.0146
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0025 0.0117
Brugia malayi hypothetical protein 0.0033 0.0034 0.0158
Brugia malayi hypothetical protein 0.0013 0.0004 0.002
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0021 0.0016 0.0008
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0016 0.0008 0.0019
Toxoplasma gondii exonuclease III APE 0.0021 0.0016 0.0058
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0013 0.0004 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0029 0.0028 0.1644
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0037 0.017
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Echinococcus multilocularis neuropeptide Y receptor 0.0066 0.0081 0.0161
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0023 0.009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Trypanosoma cruzi short chain dehydrogenase, putative 0.0016 0.0008 0.0019
Toxoplasma gondii hypothetical protein 0.0033 0.0034 0.015
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3315 0.4766 1
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0033 0.0034 0.0907
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.0111
Mycobacterium ulcerans short-chain type oxidoreductase 0.0016 0.0008 0.0008
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0008 0.0008
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Echinococcus granulosus glycine receptor subunit alpha 1 0.0063 0.0076 0.0247
Echinococcus multilocularis nAChR subunit 0.0034 0.0034 0.0063
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0008 0.0008
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Entamoeba histolytica hypothetical protein 0.0031 0.003 0.0781
Echinococcus multilocularis Smad4 0.0018 0.0011 0.0015
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0019
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0029 0.0028 0.005
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0066 0.0081 0.0161
Echinococcus granulosus glycine receptor subunit beta 0.0063 0.0076 0.0247
Onchocerca volvulus 0.0205 0.0281 0.4032
Loa Loa (eye worm) nucleotidyl transferase 0.0034 0.0035 0.0166
Loa Loa (eye worm) hypothetical protein 0.021 0.0289 0.1359
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.003 0.0122
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0063 0.0076 0.0151
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0029 0.0027 0.0049
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0016 0.0054
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0016 0.0054
Echinococcus multilocularis nAChR subunit 0.0063 0.0076 0.0151
Schistosoma mansoni inositol monophosphatase 0.0036 0.0037 0.0345
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0228 0.0314 0.1478
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0137 0.1382
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0008 0.0019
Mycobacterium leprae Probable oxidoreductase 0.0016 0.0008 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0137 0.9239
Echinococcus granulosus nAChR subunit 0.0034 0.0034 0.0104
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0066 0.0081 0.038
Echinococcus multilocularis GPCR, family 2 0.0065 0.0079 0.0158
Echinococcus granulosus neuropeptides capa receptor 0.0066 0.0081 0.0263
Echinococcus multilocularis neuropeptides capa receptor 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.014 0.0188 0.0883
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0031 0.003 0.0132
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0016 0.0008 0.0008
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0016 0.0008 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.003 0.0122
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0004 0.002
Echinococcus multilocularis ankyrin repeat protein 0.0155 0.021 0.0432
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.0322 0.0667
Leishmania major GDP-mannose pyrophosphorylase 0.0034 0.0035 0.0146
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0007 0.0032
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0013 0.0004 0.0004
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0074 0.0093 0.0436
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Schistosoma mansoni neuropeptide F-like receptor 0.0066 0.0081 0.0796
Echinococcus multilocularis neuropeptide receptor 0.0066 0.0081 0.0161
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0021 0.0016 0.006
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0037 0.2093
Trypanosoma brucei nucleotidyl transferase, putative 0.0034 0.0035 0.0146
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0063 0.0076 0.0358
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0013 0.0639
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) LGC-31 protein 0.0063 0.0076 0.0358
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0008 0.0004
Brugia malayi hypothetical protein 0.0033 0.0034 0.0158
Mycobacterium ulcerans dehydrogenase 0.0016 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0139
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0035 0.0064
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0076 0.0747
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0041
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0027 0.1568
Entamoeba histolytica hypothetical protein 0.0021 0.0016 0.0274
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0013 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0066 0.0081 0.0263
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0016 0.0008 0.0039
Brugia malayi RE15519p 0.0066 0.0081 0.038
Schistosoma mansoni nAChR subunit 0.0029 0.0027 0.0241
Brugia malayi CHE-14 protein 0.009 0.0116 0.0545
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0008 0.0014
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.003 0.1775
Echinococcus granulosus mannose 1 phosphate guanyltransferase 0.0034 0.0035 0.0106
Leishmania major short chain dehydrogenase-like protein 0.0016 0.0008 0.0019
Echinococcus granulosus alpha 1A adrenergic receptor 0.0066 0.0081 0.0263
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0029 0.0028 0.0081
Schistosoma mansoni hypothetical protein 0.0048 0.0054 0.0521
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0117
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0008 0.0019
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.1206 0.1725 0.1724
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0027 0.0129
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.0137 0.0279
Echinococcus multilocularis sex peptide receptor 0.0066 0.0081 0.0161
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0063 0.0076 0.0151
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0112 0.0147 0.03
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0063 0.0076 0.0358
Echinococcus granulosus biogenic amine 5HT receptor 0.0066 0.0081 0.0263
Brugia malayi hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0016 0.0008 0.0004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.0314 0.0651
Mycobacterium tuberculosis Probable dehydrogenase 0.0016 0.0008 0.0004
Schistosoma mansoni hypothetical protein 0.0066 0.0081 0.0796
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0013 0.0004 0.0004
Toxoplasma gondii cytochrome p450 superfamily protein 0.1373 0.1965 1
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0112 0.0148 0.0493
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Mycobacterium tuberculosis Possible transferase 0.0033 0.0034 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Leishmania major dehydrogenase-like protein 0.0016 0.0008 0.0019
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0008 0.0014
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0008 0.0008
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0027 0.6485
Echinococcus granulosus ankyrin repeat protein 0.0155 0.021 0.0706
Onchocerca volvulus 0.0066 0.0081 0.1116
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0076 0.0747
Schistosoma mansoni chromosome transmission fidelity factor 0.0031 0.003 0.0269
Brugia malayi dehydrogenases, short chain protein 2 0.0016 0.0008 0.0039
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.003 0.157
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0023 0.011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Mycobacterium ulcerans hypothetical protein 0.1206 0.1725 0.1724
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0029 0.0028 0.1644
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0008 0.0058
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0066 0.0081 0.0796
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.003 0.1775
Schistosoma mansoni hypothetical protein 0.0087 0.0111 0.1112
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0019
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Onchocerca volvulus 0.0016 0.0008 0.0058
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0035 0.0143
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0155 0.021 0.2138
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0066 0.0081 0.0796
Giardia lamblia Rab geranylgeranyltransferase 0.0112 0.0148 1
Schistosoma mansoni smad1 5 8 and 0.0018 0.0011 0.0076
Entamoeba histolytica serine acetyltransferase 1 0.0033 0.0034 0.0907
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0063 0.0076 0.0247
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0016 0.053
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Echinococcus multilocularis Niemann Pick C1 protein 0.021 0.0289 0.0598
Trichomonas vaginalis sugar-1-phosphate guanyl transferase, putative 0.0034 0.0035 0.1935
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0016 0.0008 0.0004
Leishmania major hypothetical protein, conserved 0.0033 0.0034 0.0139
Brugia malayi CXXC zinc finger family protein 0.003 0.0029 0.0138
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0156
Schistosoma mansoni inositol monophosphatase 0.0036 0.0037 0.0345
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.003 0.012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0205 0.0281 0.2878
Loa Loa (eye worm) hypothetical protein 0.0074 0.0093 0.0436
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0023 0.054
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0013 0.0004 0.0004
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0112 0.0148 1
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi Cytochrome P450 family protein 0.0013 0.0004 0.002
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0063 0.0076 0.0151
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1484 0.2126 1
Echinococcus granulosus g-protein coupled receptor 0.0066 0.0081 0.0263
Loa Loa (eye worm) inositol-1 0.0036 0.0037 0.0176
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0023 0.0019
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0023 0.009
Loa Loa (eye worm) G-protein coupled receptor 0.0066 0.0081 0.038
Plasmodium vivax steroid dehydrogenase, putative 0.0016 0.0008 0.0279
Mycobacterium tuberculosis Probable serine acetyltransferase CysE (sat) 0.0033 0.0034 0.0029
Trichomonas vaginalis mannose-1-phosphate guanyltransferase, putative 0.0033 0.0034 0.1824
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Onchocerca volvulus 0.0019 0.0013 0.0134
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Echinococcus granulosus orexin receptor type 2 0.0066 0.0081 0.0263
Brugia malayi Nucleotidyl transferase family protein 0.0034 0.0035 0.0166
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0016 0.0008 0.0019
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0031 0.003 0.0781
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi hypothetical protein 0.0031 0.003 0.0142
Schistosoma mansoni cpg binding protein 0.003 0.0029 0.0261
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0031 0.003 0.0026
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0035 0.0064
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0035 0.0163
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0013 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0016 0.0008 0.0014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0066 0.0081 0.0161
Onchocerca volvulus 0.0066 0.0081 0.1116
Loa Loa (eye worm) GABA receptor subunit 0.0034 0.0034 0.0162
Brugia malayi MH2 domain containing protein 0.0018 0.0011 0.0054
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0029 0.0028 0.0081
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0066 0.0081 0.0263
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0033 0.0034 0.0306
Echinococcus granulosus glycine receptor subunit beta 0.0063 0.0076 0.0247
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0016 0.0008 0.0014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0008 0.0008
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Onchocerca volvulus 0.0016 0.0008 0.0058
Echinococcus granulosus neuropeptides capa receptor 0.0066 0.0081 0.0263
Echinococcus multilocularis glycine receptor subunit beta 0.0063 0.0076 0.0151
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0013 0.0004 0.0004
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0016 0.0012
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Plasmodium vivax replication factor C subunit 1, putative 0.0031 0.003 0.1806
Brugia malayi cytochrome P450 0.0013 0.0004 0.002
Brugia malayi 6-phosphofructokinase 0.0105 0.0137 0.0645
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0028 0.0111
Echinococcus multilocularis neuropeptide Y receptor 0.0066 0.0081 0.0161
Schistosoma mansoni acetylcholine receptor-related 0.0029 0.0027 0.0241
Echinococcus multilocularis somatostatin receptor 0.0066 0.0081 0.0161
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0035 0.0143
Wolbachia endosymbiont of Brugia malayi carbonic anhydrase 0.0033 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus granulosus neuropeptide Y receptor 0.0066 0.0081 0.0263
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Brugia malayi hypothetical protein 0.0016 0.0008 0.0039
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0016 0.0008 0.0019
Onchocerca volvulus 0.0029 0.0027 0.0339
Giardia lamblia Translation initiation factor 0.0033 0.0034 0.1824
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Entamoeba histolytica hypothetical protein 0.0112 0.0147 0.4939
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.0314 0.1065
Loa Loa (eye worm) hypothetical protein 0.0489 0.0691 0.325
Echinococcus granulosus hypothetical protein 0.0016 0.0008 0.0014
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0013 0.0004 0.0004
Schistosoma mansoni retinal dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi Dehydrogenases, short chain protein 2 0.0016 0.0008 0.0039
Entamoeba histolytica hypothetical protein 0.0034 0.0034 0.0934
Brugia malayi zgc:92842 0.0033 0.0034 0.0158
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0025 0.0117
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.003 0.012
Loa Loa (eye worm) hypothetical protein 0.1484 0.2126 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0016 0.0073
Echinococcus granulosus neuropeptide FF receptor 2 0.0066 0.0081 0.0263
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0008 0.002
Schistosoma mansoni neuropeptide receptor 0.0066 0.0081 0.0796
Echinococcus granulosus geminin 0.068 0.0966 0.3305
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0013 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0013 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0087 0.0111 0.1112
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0037 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Echinococcus multilocularis neuropeptide receptor A26 0.0066 0.0081 0.0161
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0035 0.0104
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Plasmodium falciparum replication factor C subunit 1, putative 0.0031 0.003 0.1806
Onchocerca volvulus 0.0205 0.0281 0.4032
Brugia malayi GDP-mannose pyrophosphorylase B 0.0034 0.0035 0.0166
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0034 0.0035 0.0166
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0066 0.0081 0.0161
Leishmania major oxidoreductase-like protein 0.0016 0.0008 0.0019
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0008 0.0279
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Onchocerca volvulus 0.003 0.0029 0.0366
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Onchocerca volvulus 0.0023 0.0019 0.0219
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0037 0.2093
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus granulosus glycine receptor subunit alpha 1 0.0063 0.0076 0.0247
Schistosoma mansoni neuropeptide receptor 0.0066 0.0081 0.0796
Giardia lamblia Replication factor C, subunit 1 0.0031 0.003 0.157
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Plasmodium vivax mannose-1-phosphate guanyltransferase, putative 0.0034 0.0035 0.216
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Schistosoma mansoni smad1 5 8 and 0.0018 0.0011 0.0076
Brugia malayi 6-phosphofructokinase 0.0105 0.0137 0.0645
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0016 0.0008 0.0014
Schistosoma mansoni topbp1 0.0031 0.003 0.0269
Echinococcus granulosus dynactin 5 p25 0.0033 0.0034 0.0101
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.011
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus granulosus g protein coupled receptor 0.0066 0.0081 0.0263
Onchocerca volvulus 0.0066 0.0081 0.1116
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Leishmania major short chain dehydrogenase/reductase, putative 0.0016 0.0008 0.0019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0228 0.0314 0.1478
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0029 0.0028 0.0245
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Schistosoma mansoni cpg binding protein 0.0032 0.0032 0.0287
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi Patched protein homolog 1 0.0013 0.0004 0.002
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0028 0.0111
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0016 0.0008 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Schistosoma mansoni hypothetical protein 0.0065 0.0079 0.078
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0066 0.0081 0.0796
Giardia lamblia Rab geranylgeranyltransferase 0.0029 0.0028 0.1404
Trypanosoma cruzi hypothetical protein 0.0033 0.0034 0.0139
Schistosoma mansoni hypothetical protein 0.0014 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Loa Loa (eye worm) dehydrogenase 0.0016 0.0008 0.0039
Brugia malayi MH2 domain containing protein 0.0262 0.0363 0.1707
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0035 0.0064
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Echinococcus multilocularis nibrin 0.0031 0.003 0.0054
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0066 0.0081 0.0161
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0079 0.0158
Schistosoma mansoni ap endonuclease 0.0021 0.0016 0.0118
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0034 0.0034 0.0314
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0034 0.2052
Toxoplasma gondii carbonyl reductase 1, putative 0.0016 0.0008 0.002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Entamoeba histolytica translation initiation factor eIF-2B epsilon subunit, putative 0.0034 0.0035 0.0962
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0005 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Onchocerca volvulus 0.0016 0.0008 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Loa Loa (eye worm) dynactin 5 0.0033 0.0034 0.0158
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0016 0.0008 0.0041
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0016 0.0039
Brugia malayi Cytochrome P450 family protein 0.0013 0.0004 0.002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0068 0.0327
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Onchocerca volvulus 0.0034 0.0034 0.044
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0016 0.0015
Mycobacterium ulcerans hypothetical protein 0.0033 0.0034 0.0033
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0016 0.0008 0.0004
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0016 0.0008 0.0019
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0066 0.0081 0.0161
Brugia malayi Retinol dehydrogenase 12 0.0016 0.0008 0.0039
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0016 0.0008 0.0019
Onchocerca volvulus Putative nachr subunit 0.0063 0.0076 0.1047
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni neuropeptide receptor 0.0066 0.0081 0.0796
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0034 0.0034 0.0162
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0011 0.0015
Onchocerca volvulus 0.0029 0.0027 0.0339
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0137 0.9239
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0063 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Brugia malayi eIF4-gamma/eIF5/eIF2-epsilon family protein 0.0033 0.0034 0.0158
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0112 0.0148 0.0302
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0233 0.0322 0.1515
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796
Chlamydia trachomatis UDP-3-O-acylglucosamine N-acyltransferase 0.0033 0.0034 1
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.0137 0.0137
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0016 0.0008 0.0004
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0027 0.1568
Mycobacterium tuberculosis Conserved hypothetical protein 0.1206 0.1725 0.1721
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0027 0.1568
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0066 0.0081 0.038
Schistosoma mansoni intermediate filament proteins 0.0027 0.0025 0.0215
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0013 0.0031
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0076 0.0358
Mycobacterium ulcerans serine acetyltransferase CysE 0.0033 0.0034 0.0033
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0016 0.0008 0.0008
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0034 0.0034 0.0162
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0081 0.0796
Onchocerca volvulus 0.0063 0.0076 0.1047
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.6945 1 1
Plasmodium falciparum dynactin subunit 5, putative 0.0033 0.0034 0.2052
Leishmania major short chain dehydrogenase, putative 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0023 0.0019
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0025 0.0022 0.0017
Schistosoma mansoni carbonyl reductase 0.0016 0.0008 0.0041
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0074 0.0093 0.0921
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0033 0.0034 0.1824
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0063 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Schistosoma mansoni DNA ligase IV 0.0031 0.003 0.0269
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0032 0.0028
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Echinococcus granulosus neuropeptide receptor 0.0066 0.0081 0.0263
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Schistosoma mansoni glucosamine-1-phosphate N-acetyltransferase 0.0034 0.0035 0.0322
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0029 0.0027 0.0129
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni hypothetical protein 0.068 0.0966 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0014 0.001
Echinococcus granulosus lamin dm0 0.0027 0.0025 0.0071
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0025 0.0117
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0013 0.0063
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi phosphofructokinase 0.0105 0.0137 0.0645
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0008 0.0014
Schistosoma mansoni biogenic amine receptor 0.0066 0.0081 0.0796
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0063 0.0076 0.0358
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0137 0.0627
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0011 0.0054
Echinococcus granulosus neuropeptide receptor A26 0.0066 0.0081 0.0263
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Leishmania major pteridine reductase 1 0.0016 0.0008 0.0019
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0008 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0139
Echinococcus granulosus tachykinin peptides receptor 99D 0.0066 0.0081 0.0263
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0081 0.0161
Schistosoma mansoni opsin-like receptor 0.0066 0.0081 0.0796
Brugia malayi hypothetical protein 0.0031 0.003 0.0142
Onchocerca volvulus 0.0019 0.0013 0.0134
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0023 0.0023
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0214 0.0294 0.3009
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0063 0.0076 0.0247
Echinococcus multilocularis g-protein coupled receptor 0.0066 0.0081 0.0161
Onchocerca volvulus 0.0066 0.0081 0.1116
Echinococcus granulosus sex peptide receptor 0.0066 0.0081 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus granulosus L aminoadipate semialdehyde 0.0074 0.0093 0.0304
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0005 0.0002
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.003 0.1775
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2032 0.2915 0.6113
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Entamoeba histolytica serine acetyltransferase 1 0.0033 0.0034 0.0907
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0139
Onchocerca volvulus 0.0066 0.0081 0.1116
Loa Loa (eye worm) hypothetical protein 0.0205 0.0281 0.1322
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0066 0.0081 0.0161
Schistosoma mansoni hypothetical protein 0.0087 0.0111 0.1112
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0139
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0033 0.0034 0.0101
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0028 0.0027 0.1325
Loa Loa (eye worm) melatonin receptor type 1A 0.0066 0.0081 0.038
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0137 0.4594
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796
Trypanosoma brucei C-8 sterol isomerase, putative 0.1484 0.2126 1
Echinococcus granulosus Protein patched homolog 1 0.009 0.0116 0.0384
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0029 0.0027 0.0129
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0021 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0021 0.0016 0.1022
Leishmania major hypothetical protein, conserved 0.003 0.003 0.012
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0035 0.003
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0029 0.0027 0.0129
Trichomonas vaginalis replication factor C large subunit, putative 0.0031 0.003 0.157
Brugia malayi Dopamine receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi sulfakinin receptor protein 0.0066 0.0081 0.038
Brugia malayi Serotonin receptor 0.0066 0.0081 0.038
Trypanosoma cruzi serine acetyltransferase, putative 0.0033 0.0034 0.0139
Mycobacterium ulcerans carveol-like dehydrogenase 0.0016 0.0008 0.0008
Toxoplasma gondii eukaryotic initiation factor-2B, epsilon subunit, putative 0.0033 0.0034 0.015
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Echinococcus granulosus Niemann Pick C1 protein 0.021 0.0289 0.0978
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.003 0.012
Leishmania major serine acetyltransferase 0.0033 0.0034 0.0139
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0063 0.0076 0.0247
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Wolbachia endosymbiont of Brugia malayi 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 0.0033 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus granulosus neuropeptide receptor 0.0066 0.0081 0.0263
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Echinococcus granulosus Niemann Pick C1 protein 0.0301 0.0419 0.1425
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0031 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0176 0.0239 0.1126
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.011
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0112 0.0147 0.049
Toxoplasma gondii eukaryotic initiation factor 2B epsilon subunit, putative 0.0033 0.0034 0.015
Onchocerca volvulus 0.0066 0.0081 0.1116
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0028 0.0027 0.1325
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Onchocerca volvulus 0.0489 0.0691 1
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0063 0.0076 0.0247
Onchocerca volvulus 0.0066 0.0081 0.1116
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Brugia malayi hypothetical protein 0.0013 0.0004 0.002
Schistosoma mansoni histamine h1 receptor 0.0066 0.0081 0.0796
Schistosoma mansoni ap endonuclease 0.0021 0.0016 0.0118
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Schistosoma mansoni rab6-interacting 0.0019 0.0013 0.0095
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis oxidoreductase 0.0016 0.0008 0.0008
Plasmodium falciparum steroid dehydrogenase, putative 0.0016 0.0008 0.0279
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0008 0.0014
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0029 0.0028 0.0698
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0114
Echinococcus granulosus glycine receptor subunit alpha 1 0.0063 0.0076 0.0247
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0004 0.002
Onchocerca volvulus Sepiapterin reductase homolog 0.0016 0.0008 0.0058
Brugia malayi Cytochrome P450 family protein 0.0013 0.0004 0.002
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0063 0.0076 0.0151
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0063 0.0076 0.0358
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0029 0.0027 0.008
Echinococcus granulosus fmrfamide receptor 0.0066 0.0081 0.0263
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0035 0.212
Brugia malayi hypothetical protein 0.0233 0.0322 0.1515
Echinococcus granulosus somatostatin receptor 0.0066 0.0081 0.0263
Loa Loa (eye worm) ACC-1 protein 0.0063 0.0076 0.0358
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0066 0.0081 0.038
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.1404
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0037 0.2093
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0066 0.0081 0.0796
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0137 0.9239
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0027 0.0241
Treponema pallidum licC protein (licC) 0.1206 0.1725 1
Echinococcus multilocularis geminin 0.068 0.0966 0.202
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Brugia malayi Smad1 0.0018 0.0011 0.0054
Echinococcus granulosus intermediate filament protein 0.0027 0.0025 0.0071
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0016 0.0008 0.0008
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0016 0.0008 0.0004
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0066 0.0081 0.0263
Loa Loa (eye worm) hypothetical protein 0.009 0.0116 0.0545
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni carbonyl reductase 0.0016 0.0008 0.0041
Echinococcus multilocularis serotonin receptor 0.0066 0.0081 0.0161
Onchocerca volvulus 0.0066 0.0081 0.1116
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.003 0.157
Brugia malayi hypothetical protein 0.0016 0.0008 0.0039
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0034 0.0029
Echinococcus multilocularis musashi 0.0027 0.0025 0.0043
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Onchocerca volvulus 0.0066 0.0081 0.1116
Onchocerca volvulus 0.0066 0.0081 0.1116
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0033 0.0034 0.0158
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0035 0.0064
Echinococcus multilocularis orexin receptor type 2 0.0066 0.0081 0.0161
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0008 0.0008
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0008 0.002
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Brugia malayi hypothetical protein 0.0019 0.0013 0.0063
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0013 0.0004 0.0004
Brugia malayi isocitrate dehydrogenase 0.0034 0.0035 0.0163
Onchocerca volvulus 0.0031 0.003 0.0378
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0021 0.0016 0.0015
Schistosoma mansoni neuropeptide f receptor 76f 0.0066 0.0081 0.0796
Schistosoma mansoni hypothetical protein 0.0065 0.0079 0.078
Onchocerca volvulus 0.0027 0.0025 0.0302
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0112 0.0148 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0029 0.0028 0.0131
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0137 0.4594
Onchocerca volvulus 0.0016 0.0008 0.0058
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.0111
Schistosoma mansoni smad 0.0018 0.0011 0.0076
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Echinococcus granulosus smad 0.0018 0.0011 0.0025
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0016 0.0008 0.002
Trypanosoma cruzi short chain dehydrogenase, putative 0.0016 0.0008 0.0019
Brugia malayi Tachykinin-like peptides receptor 99D 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0016 0.0008 0.0279
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Echinococcus multilocularis neuropeptide FF receptor 2 0.0066 0.0081 0.0161
Schistosoma mansoni lipoxygenase 0.0114 0.0151 0.1522
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.0111
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0016 0.0008 0.002
Mycobacterium tuberculosis Conserved hypothetical protein 0.1206 0.1725 0.1721
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.0314 0.3222
Echinococcus multilocularis sterol regulatory element binding protein 0.009 0.0116 0.0235
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Echinococcus granulosus transient receptor potential cation channel 0.016 0.0217 0.073
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0079 0.0258
Loa Loa (eye worm) hypothetical protein 0.0065 0.0079 0.0373
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.0137 0.0627
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0066 0.0081 0.0161
Schistosoma mansoni neuropeptide receptor 0.0066 0.0081 0.0796
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0013 0.0031
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0008 0.0008
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0016 0.0008 0.0019
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0037 0.0114
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0013 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0063 0.0076 0.0151
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0066 0.0081 0.0263
Brugia malayi Inositol-1 0.0036 0.0037 0.0176
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0011 0.0054
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0156
Brugia malayi MH1 domain containing protein 0.0018 0.0011 0.0054
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0112 0.0148 0.0695
Onchocerca volvulus 0.0066 0.0081 0.1116
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni Smad4 0.0018 0.0011 0.0076
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0021 0.0016 0.0002
Brugia malayi MH1 domain containing protein 0.0018 0.0011 0.0054
Leishmania major short chain dehydrogenase/reductase, putative 0.0016 0.0008 0.0019
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Brugia malayi G protein-coupled receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0066 0.0081 0.038
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0066 0.0081 0.1116
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0066 0.0081 0.0796
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Chlamydia trachomatis DNA ligase 0.0031 0.003 0.8211
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0034 0.0139
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0013 0.0004 0.0004
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0037 0.1041
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0014 0.0013
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0016 0.0008 0.0019
Echinococcus granulosus 7TM GPCR rhodopsin 0.0066 0.0081 0.0263
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Echinococcus granulosus nAChR subunit 0.0063 0.0076 0.0247
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium tuberculosis Probable oxidoreductase 0.0301 0.042 0.0416
Brugia malayi Dopamine receptor protein 1 0.0066 0.0081 0.038
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0023 0.0019
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0011 0.0076
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0028 0.0027 0.0659
Brugia malayi Patched related family protein 10 0.0013 0.0004 0.002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0027 0.0129
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0066 0.0081 0.0796
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0081 0.0161
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Echinococcus multilocularis smad 0.0018 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0112 0.0148 0.0695
Schistosoma mansoni adenoreceptor 0.0066 0.0081 0.0796
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0016 0.0008 0.0004
Brugia malayi MH2 domain containing protein 0.0018 0.0011 0.0054
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Echinococcus granulosus g protein coupled receptor 0.0066 0.0081 0.0263
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0066 0.0081 0.0796
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0016 0.0008 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Entamoeba histolytica hypothetical protein 0.0112 0.0147 0.4939
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0012 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0066 0.0081 0.0796
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0016 0.0008 0.0019
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.021 0.0289 1
Echinococcus multilocularis mannose 1 phosphate guanyltransferase 0.0034 0.0035 0.0065
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0016 0.0073
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0079 0.0373
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0016 0.0008 0.0019
Leishmania major hypothetical protein, conserved 0.0033 0.0034 0.0139
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0014 0.0674
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0008 0.0008
Brugia malayi Cytochrome P450 family protein 0.0013 0.0004 0.002
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.0151 0.0308
Brugia malayi Cation transporter family protein 0.0205 0.0281 0.1322
Schistosoma mansoni alpha-1 adrenergic receptor 0.0066 0.0081 0.0796
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0008 0.0014
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0066 0.0081 0.038
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0023 0.0023
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0029 0.0028 0.005
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0013 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Brugia malayi GnHR receptor homolog 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0158
Echinococcus multilocularis lamin 0.0027 0.0025 0.0043
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0013 0.0004 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0023 0.011
Onchocerca volvulus 0.0066 0.0081 0.1116
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0023 0.0023
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0029 0.0027 0.0049
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0188 0.0883
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0112 0.0148 0.0695
Onchocerca volvulus 0.0016 0.0008 0.0058
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0063 0.0076 0.0151
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi Patched related family protein 4 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Schistosoma mansoni lipoxygenase 0.008 0.0101 0.1006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0079 0.0258
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Echinococcus multilocularis conserved hypothetical protein 0.0016 0.0008 0.0008
Brugia malayi G-protein coupled receptor 0.0066 0.0081 0.038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0023 0.0023
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0016 0.0024
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0016 0.0054
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Onchocerca volvulus 0.0063 0.0076 0.1047
Loa Loa (eye worm) hypothetical protein 0.0205 0.0281 0.1323
Onchocerca volvulus 0.0048 0.0054 0.0731
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0016 0.0008 0.0008
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1484 0.2126 1
Brugia malayi Cation transporter family protein 0.0063 0.0076 0.0358
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0079 0.0373
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) MH2 domain-containing protein 0.0262 0.0363 0.1707
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0016 0.0008 0.0279
Schistosoma mansoni biogenic amine receptor 0.0066 0.0081 0.0796
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi hypothetical protein 0.0112 0.0147 0.0691
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.0314 0.0651
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0066 0.0081 0.038
Entamoeba histolytica hypothetical protein 0.0112 0.0147 0.4939
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0205 0.0281 0.2878
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0037 0.0029
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.0111
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0112 0.0148 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni hypothetical protein 0.0066 0.0081 0.0796
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0016 0.0008 0.0041
Echinococcus multilocularis expressed conserved protein 0.0198 0.0271 0.0559
Schistosoma mansoni dynactin subunit P25 0.0033 0.0034 0.0306
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0013 0.0004 0.0004
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0029 0.0028 0.0111
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0033 0.0034 0.0139
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.003 0.0122
Onchocerca volvulus 0.0063 0.0076 0.1047
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0013 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0116 0.7715
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Brugia malayi excitatory GABA receptor EXP-1A 0.0063 0.0076 0.0358
Brugia malayi putative neuropeptide receptor NPR1 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0033 0.0034 0.0907
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0035 0.0155
Entamoeba histolytica serine acetyltransferase, putative 0.0033 0.0034 0.0907
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0016 0.0008 0.0004
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.0151 0.0503
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0029 0.0027 0.008
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni mannose-1-phosphate guanyltransferase 0.0034 0.0035 0.0322
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0034 0.0035 0.0106
Echinococcus multilocularis fmrfamide receptor 0.0066 0.0081 0.0161
Schistosoma mansoni rab6-interacting 0.0019 0.0013 0.0095
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0063 0.0076 0.0747
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0111 0.0145 0.0683
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus granulosus neuropeptide s receptor 0.0066 0.0081 0.0263
Schistosoma mansoni hypothetical protein 0.068 0.0966 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0156
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0081 0.0796
Brugia malayi neuropeptide F receptor 0.0066 0.0081 0.038
Mycobacterium leprae POSSIBLE TRANSFERASE 0.0033 0.0034 0.0029
Brugia malayi Dehydrogenases, short chain protein 30 0.0016 0.0008 0.0039
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0012 0.0008
Plasmodium falciparum liver specific protein 2, putative 0.0033 0.0034 0.2052
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0027 0.0129
Echinococcus multilocularis RUN 0.0019 0.0013 0.0019
Leishmania major 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Brugia malayi oxidoreductase 0.0016 0.0008 0.0039
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.009 0.0116 0.0545
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0035 0.0143
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0035 0.0155
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.0281 0.1323
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Trypanosoma cruzi Translation initiation factor eIF-2B subunit epsilon, putative 0.0034 0.0035 0.0146
Mycobacterium ulcerans hypothetical protein 0.1206 0.1725 0.1724
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Schistosoma mansoni hypothetical protein 0.0033 0.0034 0.0306
Schistosoma mansoni growth hormone secretagogue receptor 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Toxoplasma gondii GDP-D-mannose pyrophosphorylase 0.0034 0.0035 0.0158
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0035 0.0064
Plasmodium falciparum mannose-1-phosphate guanyltransferase, putative 0.0034 0.0035 0.216
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0029 0.0028 0.0131
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Schistosoma mansoni polycystin 1-related 0.0019 0.0013 0.0095
Echinococcus multilocularis lamin dm0 0.0027 0.0025 0.0043
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0025 0.0022 0.0017
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0066 0.0081 0.0161
Echinococcus granulosus cpg binding protein 0.0032 0.0032 0.0095
Schistosoma mansoni biogenic amine (5HT) receptor 0.0066 0.0081 0.0796
Brugia malayi larval opioid receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Trypanosoma cruzi FHA domain containing protein, putative 0.0031 0.003 0.0122
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Loa Loa (eye worm) G-protein coupled receptor 0.0066 0.0081 0.038
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0034 0.0034 0.0314
Echinococcus multilocularis neuropeptide s receptor 0.0066 0.0081 0.0161
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0112 0.0148 1
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0029 0.0027 0.0129
Echinococcus granulosus steroid dehydrogenase 0.0016 0.0008 0.0014
Echinococcus multilocularis allatostatin A receptor 0.0066 0.0081 0.0161
Mycobacterium ulcerans hypothetical protein 0.0026 0.0023 0.0023
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0063 0.0076 0.0358
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Toxoplasma gondii hypothetical protein 0.0029 0.0028 0.012
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Schistosoma mansoni acetylcholine receptor subunit beta 0.0029 0.0027 0.0241
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni nAChR subunit 0.0029 0.0027 0.0241
Loa Loa (eye worm) ACC-1 protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) TYRA-2 protein 0.0066 0.0081 0.038
Entamoeba histolytica hypothetical protein 0.0112 0.0147 0.4939
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0005 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.0314 0.1065
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0035 0.212
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0137 0.9239
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0034 0.1824
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0066 0.0081 0.038
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0063 0.0076 0.0151
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus multilocularis dynactin 5 p25 0.0033 0.0034 0.0062
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0016 0.0008 0.0004
Brugia malayi putative neuropeptide receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0034 0.0035 0.0065
Mycobacterium ulcerans d-alpha-D-mannose-1-phosphate guanylyltransferase ManB 0.0034 0.0035 0.0035
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Mycobacterium leprae PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) 0.0033 0.0034 0.0029
Chlamydia trachomatis acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase 0.0033 0.0034 1
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0029 0.0027 0.0049
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0021 0.0016 0.0012
Trypanosoma cruzi serine acetyltransferase, putative 0.0033 0.0034 0.0139
Schistosoma mansoni opsin-like receptor 0.0066 0.0081 0.0796
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0016 0.0008 0.0039
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Toxoplasma gondii hypothetical protein 0.0083 0.0106 0.0518
Schistosoma mansoni lamin 0.0027 0.0025 0.0215
Echinococcus multilocularis replication factor c subunit 1 0.0031 0.003 0.0054
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0078 0.0769
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0027 0.0241
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.6945 1 1
Brugia malayi intermediate filament protein 0.0027 0.0025 0.0117
Onchocerca volvulus 0.0066 0.0081 0.1116
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.0137 0.0133
Onchocerca volvulus 0.0029 0.0028 0.0344
Trypanosoma brucei oxidoreductase-like protein 0.0016 0.0008 0.0019
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0013 0.0004 0.0004
Leishmania major short chain dehydrogenase, putative 0.0016 0.0008 0.0019
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Trichomonas vaginalis glucose-1-phosphate thymidylyltransferase, putative 0.0034 0.0035 0.1935
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.0314 0.3222
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.0137 0.0133
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0112 0.0148 0.1493
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0076 0.0747
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0137 0.0645
Echinococcus granulosus g protein coupled receptor 0.0066 0.0081 0.0263
Echinococcus granulosus WW domain containing oxidoreductase 0.0016 0.0008 0.0014
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0066 0.0081 0.0161
Loa Loa (eye worm) acetylcholine receptor protein 0.0029 0.0027 0.0129
Toxoplasma gondii phosphofructokinase PFKII 0.0028 0.0027 0.0115
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0008 0.0008
Onchocerca volvulus 0.0016 0.0008 0.0058
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0028 0.0027 0.0115
Schistosoma mansoni hypothetical protein 0.0065 0.0079 0.078
Brugia malayi Patched related family protein 12 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0023 0.009
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi neuropeptide F receptor 0.0066 0.0081 0.038
Trypanosoma brucei GDP-mannose pyrophosphorylase 0.0034 0.0035 0.0146
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0023 0.011
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0005 0.0003
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0063 0.0076 0.0358
Schistosoma mansoni smad1 5 8 and 0.0018 0.0011 0.0076
Echinococcus granulosus neuropeptide Y receptor 0.0066 0.0081 0.0263
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0081 0.0796
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0079 0.0373
Echinococcus multilocularis neuropeptides capa receptor 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0027 0.6485
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0063 0.0076 0.0247
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0008 0.0008
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0063 0.0076 0.0247
Schistosoma mansoni patched 1 0.009 0.0116 0.1161
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0004 0.002
Echinococcus multilocularis protein patched 0.009 0.0116 0.0235
Brugia malayi hypothetical protein 0.003 0.003 0.014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.003 0.157
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0023 0.054
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) Smad1 0.0018 0.0011 0.0054
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0016 0.0794
Schistosoma mansoni loxhd1 0.0019 0.0013 0.0095
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Echinococcus granulosus biogenic amine 5HT receptor 0.0066 0.0081 0.0263
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0066 0.0081 0.0263
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Echinococcus multilocularis G-protein coupled receptor, putative 0.0066 0.0081 0.0161
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0063 0.0076 0.0247
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0011 0.0015
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0158
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0076 0.0358
Echinococcus multilocularis glycine receptor subunit beta 0.0063 0.0076 0.0151
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0054 0.0256
Treponema pallidum DNA ligase (lig) 0.0031 0.003 0.0085
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0014 0.0674
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0034 0.0139
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0037 0.0037
Onchocerca volvulus 0.0026 0.0023 0.0279
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0007 0.0032
Echinococcus granulosus oxidoreductase 0.0016 0.0008 0.0014
Brugia malayi ORL1-like opioid receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0029 0.0027 0.0129
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0016 0.0007
Echinococcus granulosus Smad4 0.0018 0.0011 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0112 0.0148 0.4972
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0137 0.0627
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0008 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0063 0.0076 0.0358
Echinococcus multilocularis Niemann Pick C1 protein 0.0301 0.0419 0.0871
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.1206 0.1725 0.8776
Echinococcus granulosus GPCR family 2 0.0065 0.0079 0.0258
Schistosoma mansoni biogenic amine receptor 0.0066 0.0081 0.0796
Loa Loa (eye worm) phosphofructokinase 0.0105 0.0137 0.0645
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0031 0.003 0.0142
Echinococcus granulosus sterol regulatory element binding protein 0.009 0.0116 0.0384
Echinococcus granulosus dro:myosuppressin receptor 0.0066 0.0081 0.0263
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0012 0.0008
Toxoplasma gondii ATPase, AAA family protein 0.0031 0.003 0.0132
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0066 0.0081 0.0161
Brugia malayi protein C24B5.3 0.0013 0.0004 0.002
Echinococcus granulosus expressed conserved protein 0.0198 0.0271 0.0915
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis dro:myosuppressin receptor 0.0066 0.0081 0.0161
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0034 0.0035 0.0146
Echinococcus granulosus allatostatin A receptor 0.0066 0.0081 0.0263
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0066 0.0081 0.0263
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0011 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Onchocerca volvulus 0.0066 0.0081 0.1116
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0035 0.0316
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0016 0.053
Echinococcus multilocularis cpg binding protein 0.0032 0.0032 0.0058
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0112 0.0148 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.0314 0.3222
Echinococcus multilocularis transient receptor potential cation channel 0.016 0.0217 0.0447
Loa Loa (eye worm) hypothetical protein 0.0205 0.0281 0.1322
Brugia malayi dehydrogenases, short chain protein 9 0.0016 0.0008 0.0039
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0016 0.0008 0.0008
Echinococcus granulosus nibrin 0.0031 0.003 0.0089
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0023 0.0019
Echinococcus granulosus tm gpcr rhodopsin 0.0066 0.0081 0.0263
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0063 0.0076 0.0151
Onchocerca volvulus 0.0034 0.0034 0.044
Brugia malayi topoisomerase 0.0031 0.003 0.0142
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0083 0.0106 0.6992
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Echinococcus granulosus RUN 0.0019 0.0013 0.0031
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0337 0.0471 0.0467
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0013 0.0004 0.0004
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0016 0.0054
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0023 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.003 0.0122
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Brugia malayi Myosin head containing protein 0.0013 0.0004 0.002
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0034 0.0035 0.0035
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0066 0.0081 0.038
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0016 0.0794
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0066 0.0081 0.0796
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0008 0.0014
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0013 0.0639
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.6945 1 1
Schistosoma mansoni hypothetical protein 0.0087 0.0111 0.1112
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Onchocerca volvulus 0.0016 0.0008 0.0058
Echinococcus granulosus 7tm_1 domain containing protein 0.0066 0.0081 0.0263
Onchocerca volvulus 0.0066 0.0081 0.1116
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Onchocerca volvulus 0.0016 0.0008 0.0058
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0013 0.0004 0.0004
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0137 0.1382
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Brugia malayi G-protein coupled receptor 0.0066 0.0081 0.038
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0034 0.0034 0.0162
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0008 0.0008
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0156
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.003 0.013
Loa Loa (eye worm) transcription factor SMAD2 0.0262 0.0363 0.1707
Toxoplasma gondii 6-phosphofructokinase 0.0028 0.0027 0.0115
Echinococcus multilocularis retinol dehydrogenase 13 0.0016 0.0008 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0016 0.0055
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0063 0.0076 0.0358
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Echinococcus granulosus serotonin receptor 0.0066 0.0081 0.0263
Brugia malayi hypothetical protein 0.0019 0.0013 0.0063
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0035 0.0143
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0063 0.0076 0.0247
Brugia malayi Doublecortin family protein 0.0019 0.0013 0.0063
Brugia malayi follicle stimulating hormone receptor 0.0066 0.0081 0.038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0013 0.0004 0.0004
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0066 0.0081 0.0796
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Onchocerca volvulus 0.0027 0.0025 0.0302
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0066 0.0081 0.0161
Brugia malayi Dopamine receptor protein 2 0.0066 0.0081 0.038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0066 0.0081 0.0161
Onchocerca volvulus 0.0016 0.0008 0.0058
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0016 0.0008 0.0019
Schistosoma mansoni survival motor neuron protein 0.0048 0.0054 0.0521
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Leishmania major phosphopantetheinyl transferase-like protein 0.0021 0.0016 0.0055
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0063 0.0076 0.0151
Onchocerca volvulus 0.0205 0.0281 0.4032
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0016 0.0008 0.0014
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.003 0.157
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi hypothetical protein 0.0033 0.0034 0.0158
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0063 0.0076 0.0358
Schistosoma mansoni gdp-mannose pyrophosphorylase b isoform 2 0.0034 0.0035 0.0322
Mycobacterium ulcerans epoxide hydrolase EphA 0.0337 0.0471 0.047
Plasmodium vivax dynactin subunit 5, putative 0.0033 0.0034 0.2052
Schistosoma mansoni hypothetical protein 0.0065 0.0079 0.078
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0035 0.0163
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0081 0.0161
Schistosoma mansoni hypothetical protein 0.014 0.0188 0.1908
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0034 0.0139
Onchocerca volvulus 0.0029 0.0027 0.0339
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0033 0.0034 0.1824
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0016 0.0815
Onchocerca volvulus 0.0016 0.0008 0.0058
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0066 0.0081 0.038
Mycobacterium tuberculosis Possible siderophore-binding protein 0.0033 0.0034 0.0029
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0011 0.0025
Entamoeba histolytica ankyrin, putative 0.0033 0.0034 0.0919
Onchocerca volvulus Neuropeptide F receptor homolog 0.0066 0.0081 0.1116
Leishmania major C-8 sterol isomerase-like protein 0.1484 0.2126 1
Schistosoma mansoni hypothetical protein 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) neuropeptide F receptor 0.0066 0.0081 0.038
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.8184 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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