Detailed information for compound 797029

Basic information

Technical information
  • TDR Targets ID: 797029
  • Name: 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphen yl)amino]-2-oxoethyl]triazole-4-carboxamide
  • MW: 408.454 | Formula: C21H24N6O3
  • H donors: 3 H acceptors: 4 LogP: 3.2 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccccc1NC(=O)c1nnn(c1N)CC(=O)Nc1ccccc1CC
  • InChi: 1S/C21H24N6O3/c1-3-14-9-5-6-10-15(14)23-18(28)13-27-20(22)19(25-26-27)21(29)24-16-11-7-8-12-17(16)30-4-2/h5-12H,3-4,13,22H2,1-2H3,(H,23,28)(H,24,29)
  • InChiKey: VEQSKMNNYWAETN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphenyl)amino]-2-oxo-ethyl]triazole-4-carboxamide
  • 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphenyl)amino]-2-oxoethyl]-4-triazolecarboxamide
  • 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphenyl)amino]-2-keto-ethyl]triazole-4-carboxamide
  • 5-amino-N-(2-ethoxyphenyl)-1-[2-[(2-ethylphenyl)amino]-2-oxo-ethyl]-1,2,3-triazole-4-carboxamide
  • NCGC00108149-01
  • C368-0448

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens ubiquitin specific peptidase 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0205 0.0281 0.4032
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.6945 1 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0078 0.0769
Echinococcus granulosus fmrfamide receptor 0.0066 0.0081 0.0263
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0066 0.0081 0.0796
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Brugia malayi protein C24B5.3 0.0013 0.0004 0.002
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0228 0.0314 0.1478
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0016 0.0008 0.0008
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0029 0.0027 0.0129
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0029 0.0028 0.005
Brugia malayi hypothetical protein 0.0489 0.0691 0.325
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Wolbachia endosymbiont of Brugia malayi 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 0.0033 0.0034 0.0025
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.1404
Schistosoma mansoni biogenic amine (5HT) receptor 0.0066 0.0081 0.0796
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0066 0.0081 0.0263
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Entamoeba histolytica serine acetyltransferase, putative 0.0033 0.0034 0.0907
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0016 0.0073
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0066 0.0081 0.0161
Echinococcus multilocularis neuropeptide receptor 0.0066 0.0081 0.0161
Onchocerca volvulus 0.0048 0.0054 0.0731
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0007 0.0032
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0025 0.0022 0.0017
Giardia lamblia Replication factor C, subunit 1 0.0031 0.003 0.157
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0029 0.0028 0.0081
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0027 0.6485
Brugia malayi hypothetical protein 0.0112 0.0147 0.0691
Brugia malayi isocitrate dehydrogenase 0.0034 0.0035 0.0163
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0079 0.0258
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0013 0.0004 0.0004
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Echinococcus granulosus RUN 0.0019 0.0013 0.0031
Schistosoma mansoni hypothetical protein 0.0014 0.0005 0.0013
Leishmania major hypothetical protein, conserved 0.003 0.003 0.012
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0008 0.0008
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0008 0.0279
Echinococcus granulosus expressed conserved protein 0.0198 0.0271 0.0915
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0076 0.0747
Entamoeba histolytica hypothetical protein 0.0112 0.0147 0.4939
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0034 0.0139
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi Dehydrogenases, short chain protein 2 0.0016 0.0008 0.0039
Brugia malayi 6-phosphofructokinase 0.0105 0.0137 0.0645
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0011 0.0025
Brugia malayi Dopamine receptor protein 2 0.0066 0.0081 0.038
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0013 0.0004 0.0004
Schistosoma mansoni patched 1 0.009 0.0116 0.1161
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0188 0.0883
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Schistosoma mansoni adenoreceptor 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0016 0.0794
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0028 0.0111
Schistosoma mansoni neuropeptide F-like receptor 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus granulosus neuropeptides capa receptor 0.0066 0.0081 0.0263
Leishmania major hypothetical protein, conserved 0.0033 0.0034 0.0139
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0016 0.0008 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.0314 0.0651
Echinococcus multilocularis lamin dm0 0.0027 0.0025 0.0043
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0037 0.0029
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0013 0.0639
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0063 0.0076 0.0151
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Loa Loa (eye worm) Smad1 0.0018 0.0011 0.0054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0012 0.0008
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0008 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0066 0.0081 0.0796
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0116 0.7715
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis neuropeptide FF receptor 2 0.0066 0.0081 0.0161
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0008 0.0014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0016 0.0008 0.0008
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0028 0.0027 0.1325
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0112 0.0148 0.0695
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0016 0.0008 0.002
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0028 0.0111
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0013 0.0004 0.0004
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0205 0.0281 0.2878
Echinococcus multilocularis cpg binding protein 0.0032 0.0032 0.0058
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0066 0.0081 0.0796
Echinococcus multilocularis musashi 0.0027 0.0025 0.0043
Brugia malayi Pax transcription activation domain interacting protein 0.0031 0.003 0.0142
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0008 0.0014
Brugia malayi hypothetical protein 0.0033 0.0034 0.0158
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0023 0.0019
Schistosoma mansoni opsin-like receptor 0.0066 0.0081 0.0796
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Schistosoma mansoni retinal dehydrogenase 0.0016 0.0008 0.0041
Mycobacterium leprae PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) 0.0033 0.0034 0.0029
Echinococcus granulosus tm gpcr rhodopsin 0.2032 0.2915 1
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0021 0.0016 0.1022
Onchocerca volvulus 0.0016 0.0008 0.0058
Brugia malayi eIF4-gamma/eIF5/eIF2-epsilon family protein 0.0033 0.0034 0.0158
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Onchocerca volvulus Neuropeptide F receptor homolog 0.0066 0.0081 0.1116
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0016 0.0008 0.0004
Schistosoma mansoni neuropeptide receptor 0.0066 0.0081 0.0796
Echinococcus multilocularis glycine receptor subunit beta 0.0063 0.0076 0.0151
Echinococcus multilocularis RUN 0.0019 0.0013 0.0019
Mycobacterium tuberculosis Probable serine acetyltransferase CysE (sat) 0.0033 0.0034 0.0029
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0029 0.0028 0.1644
Schistosoma mansoni smad1 5 8 and 0.0018 0.0011 0.0076
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0023 0.0023
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0031 0.003 0.0029
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0034 0.0034 0.0162
Loa Loa (eye worm) hypothetical protein 0.014 0.0188 0.0883
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0066 0.0081 0.038
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0013 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0013 0.0063
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.003 0.012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi ORL1-like opioid receptor 0.0066 0.0081 0.038
Echinococcus multilocularis protein dispatched 1 0.0103 0.0134 0.0273
Schistosoma mansoni glucosamine-1-phosphate N-acetyltransferase 0.0034 0.0035 0.0322
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0016 0.0008 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0023 0.0023
Brugia malayi Patched related family protein 12 0.0013 0.0004 0.002
Brugia malayi GDP-mannose pyrophosphorylase B 0.0034 0.0035 0.0166
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0023 0.0023
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0016 0.0008 0.0019
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.021 0.0289 1
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0139
Schistosoma mansoni lamin 0.0027 0.0025 0.0215
Echinococcus granulosus Smad4 0.0018 0.0011 0.0025
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0063 0.0076 0.0358
Echinococcus granulosus lamin dm0 0.0027 0.0025 0.0071
Schistosoma mansoni hypothetical protein 0.0087 0.0111 0.1112
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0079 0.0158
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.0111
Echinococcus multilocularis orexin receptor type 2 0.0066 0.0081 0.0161
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Schistosoma mansoni carbonyl reductase 0.0016 0.0008 0.0041
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Schistosoma mansoni hypothetical protein 0.0112 0.0147 0.1483
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.003 0.0122
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0063 0.0076 0.0358
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0029 0.0027 0.0049
Leishmania major hypothetical protein, conserved 0.0033 0.0034 0.0139
Mycobacterium ulcerans short-chain type oxidoreductase 0.0016 0.0008 0.0008
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Schistosoma mansoni mannose-1-phosphate guanyltransferase 0.0034 0.0035 0.0322
Echinococcus granulosus g protein coupled receptor 0.0066 0.0081 0.0263
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Toxoplasma gondii ATPase, AAA family protein 0.0031 0.003 0.0132
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0022
Giardia lamblia Rab geranylgeranyltransferase 0.0029 0.0028 0.1404
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus granulosus alpha 1A adrenergic receptor 0.0066 0.0081 0.0263
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0008 0.0008
Schistosoma mansoni topbp1 0.0031 0.003 0.0269
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0065 0.0079 0.0373
Brugia malayi Patched protein homolog 1 0.0013 0.0004 0.002
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0013 0.0004 0.0004
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0066 0.0081 0.0161
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0139
Echinococcus multilocularis glycine receptor subunit beta 0.0063 0.0076 0.0151
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0034 0.0034 0.0162
Brugia malayi hypothetical protein 0.002 0.0014 0.0066
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.0137 0.0133
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.003 0.013
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0137 0.9239
Loa Loa (eye worm) hypothetical protein 0.0759 0.108 0.5078
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0016 0.0008 0.0039
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.0151 0.0503
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0066 0.0081 0.038
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Echinococcus granulosus nAChR subunit 0.0034 0.0034 0.0104
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.003 0.157
Echinococcus multilocularis L aminoadipate semialdehyde 0.0074 0.0093 0.0186
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0112 0.0148 0.0302
Onchocerca volvulus 0.0205 0.0281 0.4032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Schistosoma mansoni biogenic amine receptor 0.0066 0.0081 0.0796
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0034 0.0139
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0016 0.053
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.003 0.157
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0012 0.0008
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0066 0.0081 0.0263
Echinococcus multilocularis g-protein coupled receptor 0.0066 0.0081 0.0161
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0016 0.0008 0.0019
Echinococcus granulosus hypothetical protein 0.0066 0.0081 0.0263
Entamoeba histolytica hypothetical protein 0.0021 0.0016 0.0274
Echinococcus multilocularis neuropeptide Y receptor 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0074 0.0093 0.0436
Schistosoma mansoni hypothetical protein 0.0065 0.0079 0.078
Echinococcus granulosus neuropeptide s receptor 0.0066 0.0081 0.0263
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0066 0.0081 0.1116
Brugia malayi Tachykinin-like peptides receptor 99D 0.0066 0.0081 0.038
Echinococcus multilocularis protein patched 0.009 0.0116 0.0235
Brugia malayi Inositol-1 0.0036 0.0037 0.0176
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0029 0.0027 0.0129
Brugia malayi neuropeptide F receptor 0.0066 0.0081 0.038
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0034 0.0035 0.0065
Echinococcus granulosus glycine receptor subunit alpha 1 0.0063 0.0076 0.0247
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0023 0.011
Echinococcus granulosus tachykinin peptides receptor 99D 0.0066 0.0081 0.0263
Onchocerca volvulus 0.0016 0.0008 0.0058
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0028 0.0027 0.0065
Onchocerca volvulus 0.0066 0.0081 0.1116
Loa Loa (eye worm) cytochrome P450 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.0137 0.0712
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Trypanosoma brucei oxidoreductase-like protein 0.0016 0.0008 0.0019
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0037 0.2093
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0063 0.0076 0.0358
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0037 0.2093
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0008 0.0008
Schistosoma mansoni smad1 5 8 and 0.0018 0.0011 0.0076
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0029 0.0028 0.1644
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis neuropeptide Y receptor 0.0066 0.0081 0.0161
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.003 0.157
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0011 0.0025
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0035 0.0064
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0029 0.0138
Echinococcus granulosus mannose 1 phosphate guanyltransferase 0.0034 0.0035 0.0106
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0301 0.042 0.042
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Echinococcus granulosus lamin 0.0027 0.0025 0.0071
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0016 0.0008 0.0019
Schistosoma mansoni biogenic amine receptor 0.0066 0.0081 0.0796
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0074 0.0093 0.0921
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0035 0.003
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0037 0.007
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Treponema pallidum licC protein (licC) 0.1206 0.1725 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0012 0.0008
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0032 0.0028
Schistosoma mansoni lipoxygenase 0.0114 0.0151 0.1522
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0021 0.0016 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi MH1 domain containing protein 0.0018 0.0011 0.0054
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0037 0.017
Chlamydia trachomatis DNA ligase 0.0031 0.003 0.8211
Schistosoma mansoni nAChR subunit 0.0029 0.0027 0.0241
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0027 0.0129
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0076 0.0358
Echinococcus multilocularis fmrfamide receptor 0.0066 0.0081 0.0161
Echinococcus granulosus orexin receptor type 2 0.0066 0.0081 0.0263
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0137 0.4594
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0016 0.0008 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0021 0.0016 0.0002
Schistosoma mansoni hypothetical protein 0.0048 0.0054 0.0521
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0117
Echinococcus granulosus nAChR subunit 0.0063 0.0076 0.0247
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0076 0.0358
Brugia malayi Dopamine receptor protein 1 0.0066 0.0081 0.038
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0079 0.0373
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Echinococcus multilocularis lamin 0.0027 0.0025 0.0043
Plasmodium vivax dynactin subunit 5, putative 0.0033 0.0034 0.2052
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0034 0.0034 0.0314
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0034 0.0035 0.0106
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.003 0.012
Mycobacterium ulcerans d-alpha-D-mannose-1-phosphate guanylyltransferase ManB 0.0034 0.0035 0.0035
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0066 0.0081 0.0263
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0034 0.0035 0.0146
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0021 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Onchocerca volvulus 0.0016 0.0008 0.0058
Brugia malayi hypothetical protein 0.0013 0.0004 0.002
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Entamoeba histolytica ankyrin, putative 0.0033 0.0034 0.0919
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Onchocerca volvulus 0.0029 0.0028 0.0344
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0063 0.0076 0.0151
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.0314 0.3222
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Loa Loa (eye worm) hypothetical protein 0.0111 0.0145 0.0683
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Trypanosoma brucei C-8 sterol isomerase, putative 0.1484 0.2126 1
Giardia lamblia Rab geranylgeranyltransferase 0.0112 0.0148 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0029 0.0028 0.005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0066 0.0081 0.0161
Loa Loa (eye worm) melatonin receptor type 1A 0.0066 0.0081 0.038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0023 0.0019
Schistosoma mansoni hypothetical protein 0.0065 0.0079 0.078
Schistosoma mansoni hypothetical protein 0.068 0.0966 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium tuberculosis Possible siderophore-binding protein 0.0033 0.0034 0.0029
Plasmodium vivax steroid dehydrogenase, putative 0.0016 0.0008 0.0279
Onchocerca volvulus 0.0063 0.0076 0.1047
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0205 0.0281 0.1323
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0027 0.0129
Toxoplasma gondii exonuclease III APE 0.0021 0.0016 0.0058
Toxoplasma gondii hypothetical protein 0.0083 0.0106 0.0518
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0031 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0027 0.1568
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0081 0.0796
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Giardia lamblia Translation initiation factor 0.0033 0.0034 0.1824
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0035 0.0155
Onchocerca volvulus 0.0066 0.0081 0.1116
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0063 0.0076 0.0358
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Echinococcus granulosus neuropeptide receptor 0.0066 0.0081 0.0263
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0027 0.1568
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0063 0.0076 0.0151
Brugia malayi Patched related family protein 10 0.0013 0.0004 0.002
Schistosoma mansoni hypothetical protein 0.0033 0.0034 0.0306
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0158
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0063 0.0076 0.0247
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3315 0.4766 1
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Echinococcus granulosus oxidoreductase 0.0016 0.0008 0.0014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0005 0.0001
Echinococcus granulosus hypothetical protein 0.0016 0.0008 0.0014
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0023 0.054
Echinococcus multilocularis allatostatin A receptor 0.0066 0.0081 0.0161
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0137 0.9239
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0066 0.0081 0.0161
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0035 0.0143
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0016 0.053
Echinococcus granulosus sterol regulatory element binding protein 0.009 0.0116 0.0384
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0008 0.0008
Brugia malayi hypothetical protein 0.0033 0.0034 0.0158
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0029 0.0028 0.0111
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0016 0.0008 0.0008
Brugia malayi MH2 domain containing protein 0.0018 0.0011 0.0054
Mycobacterium ulcerans epoxide hydrolase EphA 0.0337 0.0471 0.047
Entamoeba histolytica hypothetical protein 0.0112 0.0147 0.4939
Onchocerca volvulus 0.0066 0.0081 0.1116
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0205 0.0281 0.1322
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Treponema pallidum DNA ligase (lig) 0.0031 0.003 0.0085
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0016 0.0008 0.0019
Brugia malayi Cytochrome P450 family protein 0.0013 0.0004 0.002
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0063 0.0076 0.0151
Brugia malayi hypothetical protein 0.0013 0.0004 0.002
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0013 0.0004 0.0004
Onchocerca volvulus 0.0034 0.0034 0.044
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0081 0.0161
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0033 0.0034 0.0907
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0112 0.0148 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0034 0.0035 0.0146
Schistosoma mansoni inositol monophosphatase 0.0036 0.0037 0.0345
Loa Loa (eye worm) hypothetical protein 0.0176 0.0239 0.1126
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Trypanosoma cruzi short chain dehydrogenase, putative 0.0016 0.0008 0.0019
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0063 0.0076 0.0358
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0156
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.009 0.0116 0.0545
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0016 0.053
Brugia malayi hypothetical protein 0.0019 0.0013 0.0063
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi sulfakinin receptor protein 0.0066 0.0081 0.038
Onchocerca volvulus 0.0034 0.0034 0.044
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0013 0.0004 0.0004
Brugia malayi MH2 domain containing protein 0.0018 0.0011 0.0054
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0112 0.0148 0.0493
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0016 0.0008 0.0014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0016 0.0008 0.002
Schistosoma mansoni nAChR subunit 0.0029 0.0027 0.0241
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0035 0.0143
Onchocerca volvulus 0.0066 0.0081 0.1116
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Brugia malayi follicle stimulating hormone receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0233 0.0322 0.1515
Onchocerca volvulus 0.0031 0.003 0.0378
Onchocerca volvulus 0.0066 0.0081 0.1116
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0137 0.0645
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0112 0.0148 0.1493
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Echinococcus granulosus WW domain containing oxidoreductase 0.0016 0.0008 0.0014
Brugia malayi hypothetical protein 0.0019 0.0013 0.0063
Toxoplasma gondii hypothetical protein 0.0029 0.0028 0.012
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0063 0.0076 0.0247
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0034 0.0034 0.0314
Schistosoma mansoni smad1 5 8 and 0.0018 0.0011 0.0076
Mycobacterium tuberculosis Probable dehydrogenase 0.0016 0.0008 0.0004
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Brugia malayi Doublecortin family protein 0.0019 0.0013 0.0063
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0037 0.0114
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0027 0.0241
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.003 0.157
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0011 0.0054
Onchocerca volvulus 0.0066 0.0081 0.1116
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0004 0.002
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0027 0.1568
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0019
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0066 0.0081 0.038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.0314 0.0651
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0214 0.0294 0.3009
Brugia malayi Myosin head containing protein 0.0013 0.0004 0.002
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Echinococcus granulosus neuropeptide Y receptor 0.0066 0.0081 0.0263
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Trypanosoma brucei GDP-mannose pyrophosphorylase 0.0034 0.0035 0.0146
Schistosoma mansoni hypothetical protein 0.0019 0.0013 0.0095
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Echinococcus granulosus steroid dehydrogenase 0.0016 0.0008 0.0014
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0205 0.0281 0.2878
Brugia malayi Serotonin receptor 0.0066 0.0081 0.038
Toxoplasma gondii carbonyl reductase 1, putative 0.0016 0.0008 0.002
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0035 0.0064
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi putative neuropeptide receptor NPR1 0.0066 0.0081 0.038
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0016 0.0008 0.0014
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0063 0.0076 0.0358
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0081 0.0161
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0068 0.0327
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0066 0.0081 0.038
Echinococcus multilocularis dynactin 5 p25 0.0033 0.0034 0.0062
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.0281 0.1323
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0004 0.002
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0008 0.0019
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0013 0.0019
Plasmodium falciparum replication factor C subunit 1, putative 0.0031 0.003 0.1806
Mycobacterium ulcerans dehydrogenase 0.0016 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.1206 0.1725 0.1724
Echinococcus multilocularis sterol regulatory element binding protein 0.009 0.0116 0.0235
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Echinococcus multilocularis conserved hypothetical protein 0.0016 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Entamoeba histolytica hypothetical protein 0.0112 0.0147 0.4939
Schistosoma mansoni growth hormone secretagogue receptor 0.0066 0.0081 0.0796
Echinococcus multilocularis replication factor c subunit 1 0.0031 0.003 0.0054
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0063 0.0076 0.0358
Plasmodium falciparum steroid dehydrogenase, putative 0.0016 0.0008 0.0279
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0033 0.0034 0.0062
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Toxoplasma gondii cytochrome p450 superfamily protein 0.1373 0.1965 1
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0025 0.0022 0.0017
Schistosoma mansoni hypothetical protein 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0137 0.0627
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0035 0.0064
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.009 0.0116 0.0545
Brugia malayi Cation transporter family protein 0.0205 0.0281 0.1322
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0011 0.0015
Brugia malayi MH2 domain containing protein 0.0262 0.0363 0.1707
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0011 0.0076
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0016 0.0008 0.0019
Schistosoma mansoni chromosome transmission fidelity factor 0.0031 0.003 0.0269
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0034 0.0029
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0016 0.0008 0.002
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Loa Loa (eye worm) nucleotidyl transferase 0.0034 0.0035 0.0166
Brugia malayi G protein-coupled receptor F59B2.13 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi hypothetical protein 0.0033 0.0034 0.0158
Trypanosoma cruzi serine acetyltransferase, putative 0.0033 0.0034 0.0139
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.003 0.1775
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0083 0.0106 0.6992
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Schistosoma mansoni cpg binding protein 0.0032 0.0032 0.0287
Leishmania major serine acetyltransferase 0.0033 0.0034 0.0139
Schistosoma mansoni hypothetical protein 0.0087 0.0111 0.1112
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Trypanosoma cruzi hypothetical protein 0.0033 0.0034 0.0139
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0337 0.0471 0.0467
Loa Loa (eye worm) hypothetical protein 0.021 0.0289 0.1359
Brugia malayi Cation transporter family protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.011
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1484 0.2126 1
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0137 0.9239
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0054 0.0256
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0066 0.0081 0.0796
Plasmodium vivax replication factor C subunit 1, putative 0.0031 0.003 0.1806
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Brugia malayi G-protein coupled receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0012 0.0008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0066 0.0081 0.0161
Loa Loa (eye worm) MH2 domain-containing protein 0.0262 0.0363 0.1707
Echinococcus granulosus intermediate filament protein 0.0027 0.0025 0.0071
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0035 0.0316
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0079 0.0373
Mycobacterium leprae Probable oxidoreductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.011
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Onchocerca volvulus 0.0027 0.0025 0.0302
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0112 0.0148 0.0695
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi CXXC zinc finger family protein 0.003 0.0029 0.0138
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0035 0.0143
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0016 0.0008 0.0004
Trypanosoma cruzi serine acetyltransferase, putative 0.0033 0.0034 0.0139
Loa Loa (eye worm) G-protein coupled receptor 0.0066 0.0081 0.038
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.003 0.0122
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0112 0.0147 0.4939
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Schistosoma mansoni hypothetical protein 0.0087 0.0111 0.1112
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0023 0.009
Brugia malayi G protein-coupled receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Brugia malayi topoisomerase 0.0031 0.003 0.0142
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Echinococcus multilocularis serotonin receptor 0.0066 0.0081 0.0161
Mycobacterium ulcerans hypothetical protein 0.0026 0.0023 0.0023
Wolbachia endosymbiont of Brugia malayi carbonic anhydrase 0.0033 0.0034 0.0025
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0023 0.054
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0029 0.0028 0.0081
Schistosoma mansoni cpg binding protein 0.003 0.0029 0.0261
Echinococcus granulosus 7tm_1 domain containing protein 0.0066 0.0081 0.0263
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0008 0.0019
Schistosoma mansoni alpha-1 adrenergic receptor 0.0066 0.0081 0.0796
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0016 0.0008 0.0004
Echinococcus granulosus biogenic amine 5HT receptor 0.0066 0.0081 0.0263
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Brugia malayi cytochrome P450 0.0013 0.0004 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0035 0.212
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Brugia malayi intermediate filament protein 0.0027 0.0025 0.0117
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Onchocerca volvulus 0.0066 0.0081 0.1116
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.003 0.0122
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Plasmodium falciparum mannose-1-phosphate guanyltransferase, putative 0.0034 0.0035 0.216
Mycobacterium ulcerans oxidoreductase 0.0016 0.0008 0.0008
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0033 0.0034 0.0907
Toxoplasma gondii eukaryotic initiation factor-2B, epsilon subunit, putative 0.0033 0.0034 0.015
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Loa Loa (eye worm) dynactin 5 0.0033 0.0034 0.0158
Onchocerca volvulus 0.0016 0.0008 0.0058
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Schistosoma mansoni smad 0.0018 0.0011 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0139
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0016 0.0073
Schistosoma mansoni cpg binding protein 0.0032 0.0032 0.0287
Schistosoma mansoni Smad4 0.0018 0.0011 0.0076
Brugia malayi larval opioid receptor 0.0066 0.0081 0.038
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0021 0.0016 0.006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.0137 0.0279
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0081 0.0796
Echinococcus multilocularis somatostatin receptor 0.0066 0.0081 0.0161
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0035 0.0143
Leishmania major dehydrogenase-like protein 0.0016 0.0008 0.0019
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0063 0.0076 0.0151
Mycobacterium tuberculosis Probable oxidoreductase 0.0301 0.042 0.0416
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0023 0.011
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1484 0.2126 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Onchocerca volvulus 0.0066 0.0081 0.1116
Mycobacterium ulcerans carveol-like dehydrogenase 0.0016 0.0008 0.0008
Onchocerca volvulus 0.0016 0.0008 0.0058
Leishmania major pteridine reductase 1 0.0016 0.0008 0.0019
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Brugia malayi Cytochrome P450 family protein 0.0013 0.0004 0.002
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0031 0.003 0.0781
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Loa Loa (eye worm) transcription factor SMAD2 0.0262 0.0363 0.1707
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0014 0.0674
Echinococcus granulosus Niemann Pick C1 protein 0.021 0.0289 0.0978
Loa Loa (eye worm) hypothetical protein 0.1484 0.2126 1
Echinococcus multilocularis nAChR subunit 0.0063 0.0076 0.0151
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0066 0.0081 0.0161
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Onchocerca volvulus 0.0016 0.0008 0.0058
Echinococcus multilocularis nAChR subunit 0.0034 0.0034 0.0063
Echinococcus granulosus glycine receptor subunit alpha 1 0.0063 0.0076 0.0247
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus multilocularis neuropeptides capa receptor 0.0066 0.0081 0.0161
Leishmania major short chain dehydrogenase-like protein 0.0016 0.0008 0.0019
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0028 0.0027 0.1325
Schistosoma mansoni polycystin 1-related 0.0019 0.0013 0.0095
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0029 0.0027 0.008
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0008 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Echinococcus granulosus neuropeptide receptor 0.0066 0.0081 0.0263
Mycobacterium ulcerans serine acetyltransferase CysE 0.0033 0.0034 0.0033
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0016 0.0263
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0004 0.002
Schistosoma mansoni opsin-like receptor 0.0066 0.0081 0.0796
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0029 0.0028 0.0111
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0023 0.054
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.0314 0.3222
Echinococcus granulosus geminin 0.068 0.0966 0.3305
Brugia malayi MH1 domain containing protein 0.0018 0.0011 0.0054
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0033 0.0034 0.0101
Brugia malayi AKH receptor 0.0066 0.0081 0.038
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0035 0.0064
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0016 0.0054
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0016 0.0008 0.0008
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Chlamydia trachomatis acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase 0.0033 0.0034 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.0151 0.0308
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0081 0.0796
Loa Loa (eye worm) ACC-1 protein 0.0063 0.0076 0.0358
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni histamine h1 receptor 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) GABA receptor subunit 0.0034 0.0034 0.0162
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0016 0.0008 0.0039
Toxoplasma gondii 6-phosphofructokinase 0.0028 0.0027 0.0115
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0016 0.0008 0.0019
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0029 0.0028 0.0131
Onchocerca volvulus 0.0029 0.0027 0.0339
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0016 0.0054
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Brugia malayi hypothetical protein 0.0013 0.0004 0.002
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0074 0.0093 0.0436
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0019
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0063 0.0076 0.0358
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0066 0.0081 0.038
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0016 0.0008 0.0019
Brugia malayi hypothetical protein 0.0016 0.0008 0.0039
Brugia malayi hypothetical protein 0.0016 0.0008 0.0039
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0023 0.009
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0011 0.0054
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.014
Mycobacterium tuberculosis Conserved hypothetical protein 0.1206 0.1725 0.1721
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0023 0.0019
Entamoeba histolytica serine acetyltransferase 1 0.0033 0.0034 0.0907
Mycobacterium ulcerans short chain dehydrogenase 0.0025 0.0022 0.0021
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0035 0.212
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Echinococcus multilocularis retinol dehydrogenase 13 0.0016 0.0008 0.0008
Onchocerca volvulus 0.0016 0.0008 0.0058
Onchocerca volvulus 0.0019 0.0013 0.0134
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0035 0.0163
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Schistosoma mansoni ap endonuclease 0.0021 0.0016 0.0118
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0016 0.0012
Brugia malayi Cytochrome P450 family protein 0.0013 0.0004 0.002
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0029 0.0027 0.0129
Leishmania major short chain dehydrogenase/reductase, putative 0.0016 0.0008 0.0019
Mycobacterium tuberculosis Possible transferase 0.0033 0.0034 0.0029
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.1206 0.1725 0.1724
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0066 0.0081 0.0796
Echinococcus multilocularis geminin 0.068 0.0966 0.202
Schistosoma mansoni hypothetical protein 0.0066 0.0081 0.0796
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0076 0.0747
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0063 0.0076 0.0151
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0008 0.002
Echinococcus multilocularis G protein coupled receptor 139 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Brugia malayi RE15519p 0.0066 0.0081 0.038
Brugia malayi Dehydrogenases, short chain protein 30 0.0016 0.0008 0.0039
Loa Loa (eye worm) neuropeptide F receptor 0.0066 0.0081 0.038
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0007 0.0032
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.0137 0.0457
Brugia malayi hypothetical protein 0.0233 0.0322 0.1515
Onchocerca volvulus 0.0205 0.0281 0.4032
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0063 0.0076 0.0151
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0034 0.0034 0.0162
Echinococcus multilocularis smad 0.0018 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0033 0.0034 0.2052
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0112 0.0147 0.049
Onchocerca volvulus 0.0066 0.0081 0.1116
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0079 0.0258
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0066 0.0081 0.038
Echinococcus granulosus cpg binding protein 0.0032 0.0032 0.0095
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0063 0.0076 0.0358
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus granulosus G protein coupled receptor 139 0.0066 0.0081 0.0263
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0035 0.0163
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Onchocerca volvulus 0.0016 0.0008 0.0058
Loa Loa (eye worm) G-protein coupled receptor 0.0066 0.0081 0.038
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0016 0.0008 0.0014
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0029 0.0028 0.0131
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0079 0.0373
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus granulosus Protein patched homolog 1 0.009 0.0116 0.0384
Echinococcus multilocularis GPCR, family 2 0.0065 0.0079 0.0158
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0016 0.0007
Schistosoma mansoni ap endonuclease 0.0021 0.0016 0.0118
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0034 0.2052
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0013 0.0031
Loa Loa (eye worm) phosphofructokinase 0.0105 0.0137 0.0645
Schistosoma mansoni myosin xvIII 0.0066 0.0081 0.0796
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0228 0.0314 0.1478
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Leishmania major GDP-mannose pyrophosphorylase 0.0034 0.0035 0.0146
Echinococcus multilocularis nibrin 0.0031 0.003 0.0054
Echinococcus multilocularis neuropeptide receptor 0.0066 0.0081 0.0161
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.0322 0.0667
Onchocerca volvulus 0.0066 0.0081 0.1116
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0013 0.0004 0.0004
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0023 0.0019
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796
Brugia malayi Smad1 0.0018 0.0011 0.0054
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi GnHR receptor homolog 0.0066 0.0081 0.038
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.6945 1 1
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0004 0.002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0066 0.0081 0.0796
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0021 0.0016 0.006
Schistosoma mansoni inositol monophosphatase 0.0036 0.0037 0.0345
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0137 0.0645
Trichomonas vaginalis replication factor C large subunit, putative 0.0031 0.003 0.157
Echinococcus granulosus replication factor c subunit 1 0.0031 0.003 0.0089
Entamoeba histolytica hypothetical protein 0.0034 0.0034 0.0934
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0063 0.0076 0.0247
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.0314 0.3222
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0156
Entamoeba histolytica acetyltransferase, putative 0.0033 0.0034 0.0907
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.0314 0.1065
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0066 0.0081 0.0796
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Brugia malayi Cytochrome P450 family protein 0.0013 0.0004 0.002
Echinococcus granulosus dynactin 5 p25 0.0033 0.0034 0.0101
Brugia malayi dehydrogenases, short chain protein 2 0.0016 0.0008 0.0039
Echinococcus multilocularis neuropeptide s receptor 0.0066 0.0081 0.0161
Loa Loa (eye worm) TYRA-2 protein 0.0066 0.0081 0.038
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0011 0.0015
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0112 0.0148 1
Loa Loa (eye worm) inositol-1 0.0036 0.0037 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0063 0.0076 0.0247
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0035 0.0155
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Echinococcus granulosus L aminoadipate semialdehyde 0.0074 0.0093 0.0304
Brugia malayi Serotonin receptor 0.0066 0.0081 0.038
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0028 0.0027 0.0659
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0063 0.0076 0.0151
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.1206 0.1725 0.8776
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0013 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Loa Loa (eye worm) dehydrogenase 0.0016 0.0008 0.0039
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Onchocerca volvulus 0.0029 0.0027 0.0339
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0066 0.0081 0.0796
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0025 0.0117
Brugia malayi Niemann-Pick C1 protein precursor 0.021 0.0289 0.1359
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Onchocerca volvulus 0.0074 0.0093 0.129
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.0111
Onchocerca volvulus 0.0023 0.0019 0.0219
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0032 0.0028
Entamoeba histolytica translation initiation factor eIF-2B epsilon subunit, putative 0.0034 0.0035 0.0962
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0016 0.0008 0.0039
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.003 0.012
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Toxoplasma gondii phosphofructokinase PFKII 0.0028 0.0027 0.0115
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0016 0.0008 0.0004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0037 0.2093
Chlamydia trachomatis UDP-3-O-acylglucosamine N-acyltransferase 0.0033 0.0034 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0013 0.0004 0.0004
Onchocerca volvulus 0.0066 0.0081 0.1116
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0029 0.0028 0.0245
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0079 0.0158
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0155 0.021 0.2138
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0016 0.0008 0.0019
Echinococcus granulosus glycine receptor subunit beta 0.0063 0.0076 0.0247
Echinococcus granulosus sex peptide receptor 0.0066 0.0081 0.0263
Onchocerca volvulus 0.0016 0.0008 0.0058
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0005 0.0004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0016 0.0015
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0066 0.0081 0.0263
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0016 0.0815
Schistosoma mansoni carbonyl reductase 0.0016 0.0008 0.0041
Onchocerca volvulus 0.0063 0.0076 0.1047
Loa Loa (eye worm) dehydrogenase 0.0016 0.0008 0.0039
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0014 0.0674
Schistosoma mansoni rab6-interacting 0.0019 0.0013 0.0095
Brugia malayi excitatory GABA receptor EXP-1A 0.0063 0.0076 0.0358
Onchocerca volvulus 0.0066 0.0081 0.1116
Schistosoma mansoni acetylcholine receptor subunit beta 0.0029 0.0027 0.0241
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0008 0.0008
Brugia malayi hypothetical protein 0.0066 0.0081 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0034 0.1824
Brugia malayi 6-phosphofructokinase 0.0105 0.0137 0.0645
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0063 0.0076 0.0358
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0137 0.4594
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0114
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0013 0.0004 0.0004
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0016 0.0008 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0029 0.0027 0.0129
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0066 0.0081 0.0796
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0156
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Leishmania major hypothetical protein, conserved 0.0033 0.0034 0.0139
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0033 0.0034 0.0907
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0035 0.0143
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.011
Schistosoma mansoni neuropeptide receptor 0.0066 0.0081 0.0796
Echinococcus granulosus glycine receptor subunit beta 0.0063 0.0076 0.0247
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0029 0.0027 0.0049
Loa Loa (eye worm) neuropeptide F receptor 0.0066 0.0081 0.038
Onchocerca volvulus 0.0027 0.0025 0.0302
Echinococcus multilocularis neuropeptides capa receptor 0.0066 0.0081 0.0161
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0137 0.4594
Schistosoma mansoni lamin 0.0027 0.0025 0.0215
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0016 0.0008 0.0279
Toxoplasma gondii hypothetical protein 0.0033 0.0034 0.015
Schistosoma mansoni DNA ligase IV 0.0031 0.003 0.0269
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Plasmodium falciparum liver specific protein 2, putative 0.0033 0.0034 0.2052
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0035 0.0064
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0008 0.0058
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.003 0.0122
Schistosoma mansoni transcription factor LCR-F1 0.0112 0.0147 0.1483
Brugia malayi neuropeptide F receptor 0.0066 0.0081 0.038
Echinococcus granulosus peptide allatostatin:somatostatin 0.0066 0.0081 0.0263
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Trypanosoma cruzi Translation initiation factor eIF-2B subunit epsilon, putative 0.0034 0.0035 0.0146
Schistosoma mansoni biogenic amine receptor 0.0066 0.0081 0.0796
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0033 0.0034 0.0306
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0027 0.0129
Entamoeba histolytica serine acetyltransferase 1 0.0033 0.0034 0.0907
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0008 0.0058
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.0111
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0081 0.0161
Toxoplasma gondii eukaryotic initiation factor 2B epsilon subunit, putative 0.0033 0.0034 0.015
Trichomonas vaginalis mannose-1-phosphate guanyltransferase, putative 0.0033 0.0034 0.1824
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0066 0.0081 0.0796
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Mycobacterium ulcerans transferase 0.0033 0.0034 0.0033
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0031 0.003 0.0142
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0019
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis Niemann Pick C1 protein 0.021 0.0289 0.0598
Onchocerca volvulus 0.0026 0.0023 0.0279
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0021 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0158
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.0281 0.1323
Mycobacterium ulcerans hypothetical protein 0.0033 0.0034 0.0033
Echinococcus multilocularis mannose 1 phosphate guanyltransferase 0.0034 0.0035 0.0065
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus multilocularis fmrfamide receptor 0.0066 0.0081 0.0161
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0013 0.0031
Trichomonas vaginalis sugar-1-phosphate guanyl transferase, putative 0.0034 0.0035 0.1935
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0027 0.1325
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus granulosus biogenic amine 5HT receptor 0.0066 0.0081 0.0263
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.0322 0.1092
Schistosoma mansoni gdp-mannose pyrophosphorylase b isoform 2 0.0034 0.0035 0.0322
Schistosoma mansoni intermediate filament proteins 0.0027 0.0025 0.0215
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0034 0.0034 0.0162
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0013 0.0004 0.0004
Brugia malayi hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0489 0.0691 0.325
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0016 0.0054
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0008 0.0004
Echinococcus granulosus GPCR family 2 0.0065 0.0079 0.0258
Brugia malayi Retinol dehydrogenase 12 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Mycobacterium leprae POSSIBLE TRANSFERASE 0.0033 0.0034 0.0029
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0034 0.0139
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0021 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0066 0.0081 0.038
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0016 0.0794
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0016 0.0008 0.0019
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0063 0.0076 0.0358
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0029 0.0027 0.0049
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.0137 0.0627
Brugia malayi oxidoreductase 0.0016 0.0008 0.0039
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0112 0.0148 0.4972
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0035 0.0104
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Echinococcus multilocularis transient receptor potential cation channel 0.016 0.0217 0.0447
Onchocerca volvulus Putative nachr subunit 0.0063 0.0076 0.1047
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0016 0.0008 0.0014
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0013 0.0004 0.0004
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus multilocularis Smad4 0.0018 0.0011 0.0015
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0016 0.0008 0.0019
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0008 0.0008
Echinococcus granulosus neuropeptides capa receptor 0.0066 0.0081 0.0263
Echinococcus granulosus g protein coupled receptor 0.0066 0.0081 0.0263
Schistosoma mansoni acetylcholine receptor-related 0.0029 0.0027 0.0241
Echinococcus granulosus glycine receptor subunit alpha 1 0.0063 0.0076 0.0247
Echinococcus multilocularis neuropeptide receptor A26 0.0066 0.0081 0.0161
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.003 0.1775
Echinococcus multilocularis sex peptide receptor 0.0066 0.0081 0.0161
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0016 0.0008 0.0004
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0066 0.0081 0.0161
Brugia malayi phosphofructokinase 0.0105 0.0137 0.0645
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0066 0.0081 0.038
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0029 0.0028 0.0698
Trypanosoma cruzi short chain dehydrogenase, putative 0.0016 0.0008 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi G-protein coupled receptor 0.0066 0.0081 0.038
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0129
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0112 0.0147 0.03
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.0314 0.1065
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0137 0.1382
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0034 0.0035 0.0166
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Onchocerca volvulus 0.0029 0.0027 0.0339
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0005 0.0002
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0033 0.0034 0.1824
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0025 0.0117
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.003 0.1775
Brugia malayi hypothetical protein 0.003 0.003 0.014
Schistosoma mansoni neurotransmitter gated ion channel 0.0034 0.0034 0.0314
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0014 0.001
Leishmania major 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0019
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Schistosoma mansoni neuropeptide receptor 0.0066 0.0081 0.0796
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0008 0.0008
Echinococcus multilocularis serotonin receptor 0.0066 0.0081 0.0161
Echinococcus multilocularis expressed conserved protein 0.0198 0.0271 0.0559
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.0137 0.0133
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0065
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0034 0.0035 0.0035
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0013 0.0004 0.0004
Brugia malayi zgc:92842 0.0033 0.0034 0.0158
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0137 0.9239
Brugia malayi Melatonin receptor type 1A 0.0066 0.0081 0.038
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0008 0.0004
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0137 0.1382
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0063 0.0076 0.0747
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0008 0.0004
Brugia malayi DKFZp564C0469 protein 0.0031 0.003 0.0142
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.0281 0.1323
Echinococcus granulosus g-protein coupled receptor 0.0066 0.0081 0.0263
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0016 0.0008 0.0019
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0029 0.0027 0.0129
Schistosoma mansoni neuropeptide receptor 0.0066 0.0081 0.0796
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0013 0.0004 0.0004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Echinococcus multilocularis ankyrin repeat protein 0.0155 0.021 0.0432
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0063 0.0076 0.0247
Schistosoma mansoni amine GPCR 0.0066 0.0081 0.0796
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0013 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Mycobacterium tuberculosis Conserved hypothetical protein 0.1206 0.1725 0.1721
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0016 0.0008 0.0004
Loa Loa (eye worm) ACC-1 protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0142
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Echinococcus granulosus nibrin 0.0031 0.003 0.0089
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0013 0.0019
Onchocerca volvulus 0.0489 0.0691 1
Onchocerca volvulus 0.0016 0.0008 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0027 0.0241
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0033 0.0034 0.0158
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0066 0.0081 0.0263
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0005 0.0003
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0063 0.0076 0.0151
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0016 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0066 0.0081 0.038
Brugia malayi CHE-14 protein 0.009 0.0116 0.0545
Echinococcus granulosus Niemann Pick C1 protein 0.0301 0.0419 0.1425
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0016 0.0008 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0013 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0028 0.0111
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0112 0.0148 1
Echinococcus granulosus allatostatin A receptor 0.0066 0.0081 0.0263
Schistosoma mansoni loxhd1 0.0019 0.0013 0.0095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0016 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Onchocerca volvulus 0.0066 0.0081 0.1116
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0063 0.0076 0.0747
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0008 0.0014
Mycobacterium ulcerans dehydrogenase/reductase 0.0016 0.0008 0.0008
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0031 0.003 0.0022
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0112 0.0148 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0023 0.0023
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0063 0.0076 0.0358
Echinococcus granulosus g protein coupled receptor 0.0066 0.0081 0.0263
Schistosoma mansoni lipoxygenase 0.008 0.0101 0.1006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0066 0.0081 0.0161
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0023 0.011
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Echinococcus granulosus neuropeptide receptor A26 0.0066 0.0081 0.0263
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0008 0.0008
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0016 0.0008 0.0041
Plasmodium falciparum dynactin subunit 5, putative 0.0033 0.0034 0.2052
Echinococcus multilocularis G-protein coupled receptor, putative 0.0066 0.0081 0.0161
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0008 0.0019
Mycobacterium ulcerans hypothetical protein 0.1206 0.1725 0.1724
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0027 0.6485
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0037 0.0037
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0013 0.0031
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0063 0.0076 0.0247
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0023 0.009
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0033 0.0034 0.1824
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0013 0.0019
Schistosoma mansoni dynactin subunit P25 0.0033 0.0034 0.0306
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0016 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0004
Brugia malayi putative neuropeptide receptor 0.0066 0.0081 0.038
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0013 0.0004 0.0004
Onchocerca volvulus 0.0066 0.0081 0.1116
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0016 0.0008 0.0004
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0205 0.0281 0.1322
Schistosoma mansoni hypothetical protein 0.0065 0.0079 0.078
Echinococcus granulosus serotonin receptor 0.0066 0.0081 0.0263
Echinococcus granulosus 7TM GPCR rhodopsin 0.0066 0.0081 0.0263
Leishmania major short chain dehydrogenase, putative 0.0016 0.0008 0.0019
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0016 0.0008 0.0008
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0033 0.0034 0.0907
Echinococcus multilocularis Niemann Pick C1 protein 0.0301 0.0419 0.0871
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0016 0.0815
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0016 0.0024
Onchocerca volvulus 0.0063 0.0076 0.1047
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0019
Brugia malayi dehydrogenases, short chain protein 9 0.0016 0.0008 0.0039
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0008 0.0019
Echinococcus granulosus transient receptor potential cation channel 0.016 0.0217 0.073
Echinococcus granulosus somatostatin receptor 0.0066 0.0081 0.0263
Schistosoma mansoni hypothetical protein 0.0066 0.0081 0.0796
Echinococcus granulosus hypothetical protein 0.0016 0.0008 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0081 0.0796
Leishmania major short chain dehydrogenase, putative 0.0016 0.0008 0.0019
Echinococcus multilocularis oxidoreductase 0.0016 0.0008 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0028 0.0027 0.0115
Leishmania major C-8 sterol isomerase-like protein 0.1484 0.2126 1
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0008 0.0014
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0031 0.003 0.0132
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Trichomonas vaginalis glucose-1-phosphate thymidylyltransferase, putative 0.0034 0.0035 0.1935
Brugia malayi Patched related family protein 4 0.0013 0.0004 0.002
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0063 0.0076 0.0151
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0013 0.0004 0.0004
Loa Loa (eye worm) LGC-31 protein 0.0063 0.0076 0.0358
Onchocerca volvulus 0.0016 0.0008 0.0058
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0066 0.0081 0.0796
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0066 0.0081 0.0161
Plasmodium vivax mannose-1-phosphate guanyltransferase, putative 0.0034 0.0035 0.216
Onchocerca volvulus 0.0019 0.0013 0.0134
Brugia malayi Patched family protein 0.0013 0.0004 0.002
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0016 0.0008 0.0019
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0029 0.0028 0.0111
Schistosoma mansoni nAChR subunit 0.0063 0.0076 0.0747
Loa Loa (eye worm) hypothetical protein 0.0063 0.0076 0.0358
Brugia malayi protein C24B5.3 0.0013 0.0004 0.002
Loa Loa (eye worm) acetylcholine receptor protein 0.0029 0.0027 0.0129
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0025 0.0117
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0137 0.0627
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.003 0.157
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Onchocerca volvulus 0.0066 0.0081 0.1116
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0008 0.0041
Echinococcus granulosus neuropeptide FF receptor 2 0.0066 0.0081 0.0263
Brugia malayi hypothetical protein 0.0031 0.003 0.0142
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.0137 0.0137
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0029 0.0028 0.0111
Leishmania major short chain dehydrogenase/reductase, putative 0.0016 0.0008 0.0019
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0014 0.0013
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0016 0.0055
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0016 0.0054
Schistosoma mansoni hypothetical protein 0.0065 0.0079 0.078
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0008 0.0008
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0112 0.0148 1
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0016 0.0008 0.0279
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0063 0.0076 0.0358
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0066 0.0081 0.0161
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0066 0.0081 0.0161
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Leishmania major phosphopantetheinyl transferase-like protein 0.0021 0.0016 0.0055
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0162
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0016 0.0008 0.0004
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0029 0.0027 0.008
Brugia malayi Cation transporter family protein 0.0063 0.0076 0.0358
Brugia malayi Dopamine receptor 0.0066 0.0081 0.038
Schistosoma mansoni hypothetical protein 0.0087 0.0111 0.1112
Trypanosoma cruzi FHA domain containing protein, putative 0.0031 0.003 0.0122
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0016 0.0039
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0027 0.1568
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0016 0.0008 0.0041
Echinococcus granulosus ankyrin repeat protein 0.0155 0.021 0.0706
Brugia malayi Nucleotidyl transferase family protein 0.0034 0.0035 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0139
Loa Loa (eye worm) hypothetical protein 0.0066 0.0081 0.038
Brugia malayi hypothetical protein 0.0031 0.003 0.0142
Leishmania major oxidoreductase-like protein 0.0016 0.0008 0.0019
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0063 0.0076 0.0247
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0063 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0039
Echinococcus granulosus dro:myosuppressin receptor 0.0066 0.0081 0.0263
Schistosoma mansoni opsin-like receptor 0.0066 0.0081 0.0796
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0016 0.0011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.6945 1 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0037 0.1041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.0039
Onchocerca volvulus 0.003 0.0029 0.0366
Schistosoma mansoni hypothetical protein 0.014 0.0188 0.1908
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0081 0.0161
Echinococcus granulosus neuropeptide Y receptor 0.0066 0.0081 0.0263
Trypanosoma brucei nucleotidyl transferase, putative 0.0034 0.0035 0.0146
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0081 0.0263
Echinococcus granulosus smad 0.0018 0.0011 0.0025
Brugia malayi hypothetical protein 0.0029 0.0027 0.0129
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0066 0.0081 0.0796
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0023 0.0023
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0016 0.0008 0.0019
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0156
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2032 0.2915 0.6113
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0008 0.002
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0013 0.0639
Echinococcus granulosus tm gpcr rhodopsin 0.0066 0.0081 0.0263
Loa Loa (eye worm) oxidoreductase 0.0016 0.0008 0.0039
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0066 0.0081 0.038
Echinococcus granulosus tm gpcr rhodopsin 0.0066 0.0081 0.0263
Echinococcus multilocularis dro:myosuppressin receptor 0.0066 0.0081 0.0161
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0063 0.0076 0.0247
Schistosoma mansoni neuropeptide f receptor 76f 0.0066 0.0081 0.0796
Schistosoma mansoni survival motor neuron protein 0.0048 0.0054 0.0521
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0066 0.0081 0.0263
Onchocerca volvulus 0.0066 0.0081 0.1116
Onchocerca volvulus 0.0066 0.0081 0.1116
Toxoplasma gondii GDP-D-mannose pyrophosphorylase 0.0034 0.0035 0.0158
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0013 0.0004 0.0004
Onchocerca volvulus Sepiapterin reductase homolog 0.0016 0.0008 0.0058
Schistosoma mansoni topbp1 0.0031 0.003 0.0269
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0112 0.0148 0.0695
Schistosoma mansoni carbonyl reductase 0.0016 0.0008 0.0041
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0016 0.0008 0.0058
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0013 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0066 0.0081 0.0796
Schistosoma mansoni hypothetical protein 0.068 0.0966 1
Brugia malayi hypothetical protein 0.0033 0.0034 0.0158
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0008 0.0008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0063 0.0076 0.0358
Schistosoma mansoni rab6-interacting 0.0019 0.0013 0.0095
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0016 0.0008 0.0004
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.002
Mycobacterium ulcerans oxidoreductase 0.0016 0.0008 0.0008
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0008 0.0041
Entamoeba histolytica hypothetical protein 0.0031 0.003 0.0781
Onchocerca volvulus 0.0016 0.0008 0.0058

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.8184 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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