Detailed information for compound 875435

Basic information

Technical information
  • TDR Targets ID: 875435
  • Name: N-[5-(methyl-phenylsulfamoyl)-1,3,4-thiadiazo l-2-yl]butanamide
  • MW: 340.421 | Formula: C13H16N4O3S2
  • H donors: 1 H acceptors: 5 LogP: 1.74 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(=O)Nc1nnc(s1)S(=O)(=O)N(c1ccccc1)C
  • InChi: 1S/C13H16N4O3S2/c1-3-7-11(18)14-12-15-16-13(21-12)22(19,20)17(2)10-8-5-4-6-9-10/h4-6,8-9H,3,7H2,1-2H3,(H,14,15,18)
  • InChiKey: PJIZDEBHPCEJDX-UHFFFAOYSA-N  


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Synonyms

  • N-[5-(methyl-phenyl-sulfamoyl)-1,3,4-thiadiazol-2-yl]butanamide
  • N-[5-(methyl-phenyl-sulfamoyl)-1,3,4-thiadiazol-2-yl]butyramide
  • E157-5467
  • NCGC00120684-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens mechanistic target of rapamycin (serine/threonine kinase) Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma congolense Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) phosphatidylinositol 3 Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei gambiense phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania major target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii target of rapamycin (TOR), putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania infantum target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei phosphatidylinositol 4-kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K07203 FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania mexicana phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania braziliensis target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus granulosus FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_127212 All targets in OG5_127212
Giardia lamblia GTOR Get druggable targets OG5_127212 All targets in OG5_127212
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans frameshifted from upstream TOR2 CDS (CaP19.1905) Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania mexicana phosphatidylinositol 3-kinase (tor2)-like protein Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania donovani Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum Phosphatidylinositol 3-kinase tor2, related Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans frameshifted from upsteam TOR2 CDS (CaP19.9461) Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide f receptor 76f 0.0195 0.1347 0.1746
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Schistosoma mansoni hypothetical protein 0.1034 0.7714 1
Entamoeba histolytica ribokinase, putative 0.0019 0.0013 0.0003
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0069 0.0386 0.0386
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0195 0.1347 0.1746
Echinococcus multilocularis adenosylhomocysteinase 0.0259 0.1835 0.1835
Toxoplasma gondii target of rapamycin (TOR), putative 0.004 0.0172 0.0936
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0012 0.0012
Leishmania major DNA polymerase eta, putative 0.0038 0.0157 0.0153
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0066 0.0063
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0451 0.3289 0.3289
Loa Loa (eye worm) hypothetical protein 0.019 0.1309 0.1309
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0029 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0159 0.1074 0.1074
Onchocerca volvulus 0.0195 0.1347 0.8058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0088 0.046
Leishmania major arginine N-methyltransferase-like protein 0.0122 0.079 0.0787
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0156 0.105 0.105
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0192 0.0192
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0048
Entamoeba histolytica PH domain containing protein kinase, putative 0.0159 0.1074 0.5821
Schistosoma mansoni adenosine kinase 0.0171 0.1161 0.1505
Toxoplasma gondii AGC kinase 0.0159 0.1074 0.5849
Schistosoma mansoni inositol transporter 0.0039 0.0159 0.0207
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0195 0.0195
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.066 0.3584
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0193 0.1035
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0093 0.012
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0028 0.5
Loa Loa (eye worm) hypothetical protein 0.019 0.1311 0.1311
Schistosoma mansoni adenoreceptor 0.0195 0.1347 0.1746
Echinococcus multilocularis g protein coupled receptor 0.0195 0.1347 0.1347
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0196 0.0931
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0012 0.0016
Echinococcus multilocularis neuropeptide s receptor 0.0195 0.1347 0.1347
Echinococcus multilocularis dro:myosuppressin receptor 0.0195 0.1347 0.1347
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0159 0.1074 0.107
Echinococcus multilocularis mitogen activated protein kinase 3 0.0105 0.066 0.066
Entamoeba histolytica recQ family helicase, putative 0.0023 0.004 0.0149
Echinococcus granulosus histone lysine methyltransferase setb 0.0051 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Onchocerca volvulus 0.0195 0.1347 0.8058
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0413 0.0413
Schistosoma mansoni hypothetical protein 0.0067 0.0373 0.0484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0088 0.046
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Echinococcus granulosus ribokinase 0.0019 0.0013 0.0013
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0277 0.0277
Echinococcus granulosus 7TM GPCR rhodopsin 0.0195 0.1347 0.1347
Mycobacterium ulcerans hypothetical protein 0.0029 0.0083 0.0383
Echinococcus granulosus zinc finger protein 0.0024 0.0045 0.0045
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0323 0.0323
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0195 0.1347 0.1746
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0083 0.0383
Leishmania major adenosine kinase-like protein 0.0019 0.0013 0.0009
Brugia malayi hypothetical protein 0.0019 0.0012 0.0012
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0157 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.1347 0.1746
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0029 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0088 0.0458
Leishmania major cytochrome p450-like protein 0.0022 0.0029 0.0025
Entamoeba histolytica hypothetical protein 0.0043 0.0195 0.1003
Brugia malayi Serotonin receptor 0.0195 0.1347 0.1347
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.066 0.0856
Loa Loa (eye worm) TYRA-2 protein 0.0195 0.1347 0.1347
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0259 0.1835 0.1832
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0157 0.0203
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0029 0.0088
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Leishmania major hypothetical protein, conserved 0.0018 0.0006 0.0002
Giardia lamblia GTOR 0.0054 0.0277 0.2585
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0036 0.0036
Loa Loa (eye worm) neuropeptide F receptor 0.0195 0.1347 0.1347
Schistosoma mansoni hypothetical protein 0.0031 0.01 0.013
Brugia malayi ORL1-like opioid receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.01 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0088 0.046
Onchocerca volvulus 0.0195 0.1347 0.8058
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0029 0.0082
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0105 0.066 0.0657
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0159 0.1074 0.107
Brugia malayi Carm1-pending protein 0.0069 0.0386 0.0386
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0039 0.0159 0.0869
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0196 0.0192
Mycobacterium ulcerans beta-lactamase 0.0043 0.0196 0.1002
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0029 0.0082
Leishmania major C-8 sterol isomerase-like protein 0.0372 0.269 0.2688
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0069 0.0386 0.0386
Echinococcus granulosus dna polymerase eta 0.0038 0.0157 0.0157
Schistosoma mansoni hypothetical protein 0.0018 0.0006 0.0007
Trypanosoma brucei unspecified product 0.0026 0.0066 0.0063
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0083 0.0356
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0043 0.0196 0.0196
Leishmania major protein kinase A catalytic subunit isoform 2 0.0159 0.1074 0.107
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0105 0.066 0.3597
Leishmania major cytochrome p450-like protein 0.0039 0.0164 0.016
Echinococcus multilocularis adenosine kinase 0.0171 0.1161 0.1161
Schistosoma mansoni opsin-like receptor 0.0195 0.1347 0.1746
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0029 0.0088
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0081 0.0484 0.2621
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0012 0.0016
Schistosoma mansoni hypothetical protein 0.0043 0.0195 0.0253
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0019 0.0013 0.0013
Schistosoma mansoni adenosylhomocysteinase 0.0161 0.1084 0.1406
Loa Loa (eye worm) hypothetical protein 0.0034 0.0125 0.0125
Echinococcus multilocularis solute carrier family 5 0.0039 0.0159 0.0159
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0196 0.0931
Brugia malayi follicle stimulating hormone receptor 0.0658 0.4863 0.4863
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.1347 0.1746
Trypanosoma cruzi cytochrome P450, putative 0.0039 0.0164 0.016
Echinococcus multilocularis G protein coupled receptor 139 0.0195 0.1347 0.1347
Entamoeba histolytica hypothetical protein 0.0043 0.0195 0.1003
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Onchocerca volvulus 0.0195 0.1347 0.8058
Schistosoma mansoni sodium/solute symporter 0.0039 0.0159 0.0207
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0029 0.0088
Onchocerca volvulus 0.0195 0.1347 0.8058
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0172 0.0919
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0029 0.0025
Entamoeba histolytica hypothetical protein 0.019 0.1311 0.7122
Loa Loa (eye worm) hypothetical protein 0.0043 0.0196 0.0196
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0277 0.0277
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0083 0.0083
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0195 0.1347 0.1347
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0083 0.0383
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0083 0.0079
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.01 0.01
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0019 0.0013 0.0003
Leishmania major protein kinase A catalytic subunit isoform 1 0.0159 0.1074 0.107
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0012 0.0016
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0195 0.0253
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0039 0.0159 0.0159
Brugia malayi Dopamine receptor protein 1 0.0195 0.1347 0.1347
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0039 0.0159 0.0159
Giardia lamblia Kinase, AGC PKA 0.0159 0.1074 1
Plasmodium vivax SET domain protein, putative 0.003 0.0093 0.0136
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0277 0.1495
Leishmania major histone-lysine N-methyltransferase, putative 0.0051 0.025 0.0247
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0039 0.0159 0.0159
Trypanosoma brucei adenosine kinase, putative 0.0171 0.1161 0.1158
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0029 0.0088
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0105 0.066 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0172 0.0919
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0195 0.1347 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0172 0.0919
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0159 0.1074 0.107
Schistosoma mansoni protein arginine n-methyltransferase 0.0069 0.0386 0.0501
Brugia malayi cytochrome P450 0.0022 0.0029 0.0029
Giardia lamblia DINP protein human, muc B family 0.0038 0.0157 0.146
Echinococcus granulosus neuropeptides capa receptor 0.0195 0.1347 0.1347
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0159 0.1074 0.219
Brugia malayi beta-lactamase family protein 0.0043 0.0196 0.0196
Brugia malayi Dopamine receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) Carm1-pending protein 0.0069 0.0386 0.0386
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0012 0.0012
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0054 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0085 0.0514 0.0514
Trypanosoma brucei Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0051 0.025 0.0247
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0036 0.0036
Leishmania major protein kinase A catalytic subunit 0.0159 0.1074 0.107
Loa Loa (eye worm) RecQ helicase 0.0043 0.0192 0.0192
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0259 0.1835 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0196 0.0931
Trypanosoma brucei histone-lysine n-methyltransferase 0.0051 0.025 0.0247
Trypanosoma brucei adenosine kinase, putative 0.0171 0.1161 0.1158
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Onchocerca volvulus Neuropeptide F receptor homolog 0.0195 0.1347 0.8058
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0029 0.0082
Loa Loa (eye worm) hypothetical protein 0.0052 0.0256 0.0256
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0195 0.1347 0.1347
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0029 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.1347 0.1746
Schistosoma mansoni blooms syndrome DNA helicase 0.0034 0.0123 0.0159
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0195 0.1347 0.1746
Schistosoma mansoni hypothetical protein 0.0031 0.01 0.013
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0195 0.1347 0.1746
Onchocerca volvulus 0.0029 0.0083 0.0422
Leishmania major hypothetical protein, conserved 0.0051 0.025 0.0247
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0249 0.0323
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0069 0.0386 0.0383
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Brugia malayi Sodium:solute symporter family protein 0.0039 0.0159 0.0159
Trypanosoma brucei cytochrome P450, putative 0.0039 0.0164 0.016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0088 0.0458
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0195 0.1347 0.1347
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0159 0.1074 0.1074
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0029 0.0088
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0012 0.0012
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0029 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0112 0.059
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0029 0.0025
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0069 0.0386 0.0383
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0159 0.1074 0.1074
Loa Loa (eye worm) hypothetical protein 0.0038 0.0157 0.0157
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Schistosoma mansoni hypothetical protein 0.0195 0.1347 0.1746
Onchocerca volvulus 0.0195 0.1347 0.8058
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0157 0.0153
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0043 0.0193 0.019
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.1335 1 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0012 0.0012
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0069 0.0386 0.0383
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Schistosoma mansoni cytochrome P450 0.0022 0.0029 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0029 0.0082
Trypanosoma cruzi adenosine kinase, putative 0.0019 0.0013 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0066 0.0063
Loa Loa (eye worm) hypothetical protein 0.0098 0.0608 0.0608
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0195 0.0195
Brugia malayi G protein-coupled receptor F59B2.13 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0399 0.2897 0.2897
Echinococcus granulosus biogenic amine 5HT receptor 0.0195 0.1347 0.1347
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0259 0.1835 0.1832
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0029 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0029 0.0082
Schistosoma mansoni neuropeptide receptor 0.0195 0.1347 0.1746
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0122 0.079 0.1597
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.1347 0.1746
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0083 0.0383
Leishmania major hypothetical protein, conserved 0.0051 0.025 0.0247
Onchocerca volvulus 0.003 0.0093 0.0481
Loa Loa (eye worm) G-protein coupled receptor 0.0195 0.1347 0.1347
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0195 0.1347 0.1347
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0195 0.1347 0.1746
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0192 0.0192
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0051 0.025 0.0247
Echinococcus multilocularis zinc finger protein 0.0024 0.0045 0.0045
Brugia malayi GH02984p 0.0351 0.2532 0.2532
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Mycobacterium ulcerans lipase LipD 0.0043 0.0196 0.1002
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0196 0.0351
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) AGC/PKA protein kinase 0.0159 0.1074 0.1074
Brugia malayi PXA domain containing protein 0.0019 0.0012 0.0012
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0054 0.0277 0.036
Brugia malayi Cytochrome P450 family protein 0.0022 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0195 0.1347 0.1347
Echinococcus multilocularis fmrfamide receptor 0.0195 0.1347 0.1347
Mycobacterium leprae putative cytochrome p450 0.0022 0.0029 0.0088
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0016
Schistosoma mansoni zinc finger protein 0.0018 0.0006 0.0007
Echinococcus multilocularis g protein coupled receptor 0.0195 0.1347 0.1347
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0067 0.0373 0.0373
Trypanosoma cruzi ISWI complex protein 0.0018 0.0006 0.0002
Plasmodium vivax S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative 0.065 0.4802 1
Trichomonas vaginalis esterase, putative 0.0043 0.0196 0.1048
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0159 0.1074 0.5849
Schistosoma mansoni biogenic amine (5HT) receptor 0.0195 0.1347 0.1746
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0195 0.1347 0.1347
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Brugia malayi hypothetical protein 0.0019 0.0012 0.0012
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0012 0.0012
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0195 0.1347 0.1746
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0196 0.1048
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0069 0.0386 0.2089
Echinococcus multilocularis neuropeptide FF receptor 2 0.0195 0.1347 0.1347
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0159 0.1074 0.1074
Echinococcus granulosus tm gpcr rhodopsin 0.0195 0.1347 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0217 0.1166
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0159 0.1074 0.107
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0157 0.0157
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0029 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0088 0.046
Loa Loa (eye worm) melatonin receptor type 1A 0.0195 0.1347 0.1347
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0122 0.079 0.1645
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0259 0.1835 0.3786
Toxoplasma gondii bicoid-interacting protein BIN3 0.0069 0.0386 0.2104
Loa Loa (eye worm) hypothetical protein 0.0029 0.0083 0.0083
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0159 0.1074 0.1074
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0083 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0048
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0105 0.066 0.0657
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0196 0.0253
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0023 0.0037 0.0033
Echinococcus multilocularis expressed protein 0.0377 0.2729 0.2729
Schistosoma mansoni opsin-like receptor 0.0195 0.1347 0.1746
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0069 0.0386 0.2104
Schistosoma mansoni adenosine kinase 0.0171 0.1161 0.1505
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0196 0.0196
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0157 0.0157
Echinococcus granulosus sodium:glucose cotransporter 0.0039 0.0159 0.0159
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.019 0.1311 0.1308
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0157 0.0153
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0157 0.0157
Echinococcus granulosus G protein coupled receptor 139 0.0195 0.1347 0.1347
Echinococcus granulosus protein arginine methyltransferase 0.0122 0.079 0.079
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0159 0.1074 0.1074
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.1335 1 1
Brugia malayi G-protein coupled receptor 0.0195 0.1347 0.1347
Trypanosoma brucei unspecified product 0.0038 0.0157 0.0153
Leishmania major adenosine kinase, putative 0.0171 0.1161 0.1158
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Brugia malayi putative neuropeptide receptor NPR1 0.0195 0.1347 0.1347
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0195 0.1347 0.1746
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0157 0.0153
Schistosoma mansoni ribokinase 0.0019 0.0013 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0142 0.0755
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0022 0.0028
Onchocerca volvulus 0.0147 0.0982 0.5851
Brugia malayi Pre-SET motif family protein 0.0209 0.145 0.145
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0195 0.1347 0.1746
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0029 0.0082
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0195 0.1347 0.1347
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.1335 1 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0195 0.1347 0.1347
Schistosoma mansoni hypothetical protein 0.0022 0.0029 0.0038
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0105 0.066 0.066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0193 0.1035
Echinococcus granulosus S adenosylmethionine decarboxylase proenzyme 0.1335 1 1
Brugia malayi Cytochrome P450 family protein 0.0039 0.0164 0.0164
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0012 0.0012
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0157 0.0157
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0026 0.006 0.0057
Brugia malayi AKH receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0171 0.1161 0.1161
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0012 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Echinococcus granulosus solute carrier family 5 0.0039 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Schistosoma mansoni adenosylhomocysteinase 0.0161 0.1084 0.1406
Echinococcus granulosus adenosine kinase 0.0171 0.1161 0.1161
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0029 0.0083 0.0083
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0109 0.0576
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0196 0.1002
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0012 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Echinococcus granulosus neuropeptide Y receptor 0.0195 0.1347 0.1347
Trypanosoma brucei C-8 sterol isomerase, putative 0.0372 0.269 0.2688
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.6194 0.6194
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0054 0.0277 0.0274
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0164 0.0164
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0012 0.0012
Toxoplasma gondii kinase, pfkB family protein 0.0019 0.0013 0.0071
Loa Loa (eye worm) hypothetical protein 0.0043 0.0196 0.0196
Schistosoma mansoni neuropeptide receptor 0.0195 0.1347 0.1746
Echinococcus granulosus protein arginine N methyltransferase 7 0.0069 0.0386 0.0386
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0083 0.0383
Toxoplasma gondii AGC kinase 0.0159 0.1074 0.5849
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Schistosoma mansoni alpha-1 adrenergic receptor 0.0195 0.1347 0.1746
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0083 0.0083
Echinococcus granulosus g-protein coupled receptor 0.0195 0.1347 0.1347
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.066 0.3584
Echinococcus multilocularis allatostatin A receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0031 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) neuropeptide F receptor 0.0195 0.1347 0.1347
Mycobacterium ulcerans hypothetical protein 0.0043 0.0196 0.1002
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.1074 0.1392
Onchocerca volvulus 0.0195 0.1347 0.8058
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0036 0.0046
Echinococcus granulosus bloom syndrome protein 0.0043 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0043 0.0196 0.0196
Echinococcus granulosus peptide allatostatin:somatostatin 0.0195 0.1347 0.1347
Brugia malayi sulfakinin receptor protein 0.0195 0.1347 0.1347
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.1074 0.1392
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0012 0.0012
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0054 0.0277 0.1454
Brugia malayi beta-lactamase 0.0043 0.0196 0.0196
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0122 0.079 0.1024
Schistosoma mansoni amine GPCR 0.0195 0.1347 0.1746
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0028 0.0076
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0029 0.0088
Schistosoma mansoni hypothetical protein 0.0195 0.1347 0.1746
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.145 0.145
Echinococcus granulosus dna polymerase kappa 0.0038 0.0157 0.0157
Brugia malayi Adenosylhomocysteinase 0.0259 0.1835 0.1835
Echinococcus granulosus g protein coupled receptor 0.0195 0.1347 0.1347
Echinococcus granulosus fmrfamide receptor 0.0195 0.1347 0.1347
Schistosoma mansoni hypothetical protein 0.0031 0.01 0.013
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0072 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Schistosoma mansoni high-affinity choline transporter 0.0351 0.2532 0.3283
Onchocerca volvulus 0.0195 0.1347 0.8058
Leishmania major tagatose-6-phosphate kinase-like protein 0.0019 0.0013 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0083 0.0383
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0029 0.0088
Loa Loa (eye worm) hypothetical protein 0.0021 0.0028 0.0028
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0083 0.0079
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0039 0.0164 0.0827
Onchocerca volvulus 0.0043 0.0196 0.1103
Schistosoma mansoni amine GPCR 0.0195 0.1347 0.1746
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0109 0.0576
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0172 0.0919
Schistosoma mansoni histamine h1 receptor 0.0195 0.1347 0.1746
Echinococcus multilocularis GPCR, family 2 0.0031 0.01 0.01
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0658 0.4863 0.4863
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0028 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0036 0.0046
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0012 0.0012
Echinococcus granulosus histone h3 methyltransferase 0.0399 0.2897 0.2897
Schistosoma mansoni adenosylhomocysteinase 0.0161 0.1084 0.1406
Toxoplasma gondii hypothetical protein 0.0051 0.025 0.1364
Toxoplasma gondii ABC1 family protein 0.0043 0.0196 0.1065
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0157 0.0733
Trypanosoma cruzi ribokinase, putative 0.0019 0.0013 0.0009
Brugia malayi PHD-finger family protein 0.003 0.0094 0.0094
Brugia malayi Bromodomain containing protein 0.0091 0.0553 0.0553
Schistosoma mansoni hypothetical protein 0.0031 0.01 0.013
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0012 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Loa Loa (eye worm) S-adenosylmethionine decarboxylase proenzyme 0.1335 1 1
Echinococcus granulosus sodium:glucose cotransporter 2 0.0039 0.0159 0.0159
Entamoeba histolytica fructokinase, putative 0.0019 0.0013 0.0003
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0004 0.0004
Schistosoma mansoni inositol transporter 0.0039 0.0159 0.0207
Brugia malayi putative neuropeptide receptor 0.0195 0.1347 0.1347
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.1335 1 1
Toxoplasma gondii kinase, pfkB family protein 0.0171 0.1161 0.6325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0193 0.1035
Brugia malayi PXA domain containing protein 0.0019 0.0012 0.0012
Trypanosoma cruzi adenosine kinase, putative 0.0171 0.1161 0.1158
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0072 0.0072
Echinococcus granulosus neuropeptide receptor 0.0195 0.1347 0.1347
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0051 0.0249 0.0249
Echinococcus multilocularis protein arginine methyltransferase 0.0122 0.079 0.079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0133 0.0706
Schistosoma mansoni neuropeptide receptor 0.0195 0.1347 0.1746
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0083 0.0386
Schistosoma mansoni histone J3 methyltransferase 0.0399 0.2897 0.3756
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0159 0.1074 0.107
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.066 0.0657
Echinococcus granulosus adenosylhomocysteinase 0.0259 0.1835 0.1835
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0172 0.0919
Brugia malayi Tachykinin-like peptides receptor 99D 0.0195 0.1347 0.1347
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0122 0.079 0.1024
Brugia malayi MAP kinase sur-1 0.0105 0.066 0.066
Trichomonas vaginalis AGC family protein kinase 0.0159 0.1074 0.5841
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0069 0.0386 0.2104
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0048
Echinococcus multilocularis fmrfamide receptor 0.0195 0.1347 0.1347
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0159 0.1074 0.107
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.01 0.01
Schistosoma mansoni biogenic amine (5HT) receptor 0.0195 0.1347 0.1746
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0029 0.0082
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0004 0.0005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0195 0.1347 0.1746
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0088 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0112 0.059
Echinococcus multilocularis rho associated protein kinase 0.0147 0.0982 0.0982
Onchocerca volvulus 0.0039 0.0159 0.0885
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0195 0.1347 0.1347
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0012 0.0012
Echinococcus multilocularis sex peptide receptor 0.0195 0.1347 0.1347
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0012 0.0016
Echinococcus granulosus mitogen activated protein kinase 3 0.0105 0.066 0.066
Trypanosoma cruzi target of rapamycin kinase 3 0.0043 0.0193 0.019
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0066 0.0063
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0029 0.0158
Brugia malayi larval opioid receptor 0.0195 0.1347 0.1347
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0029 0.0082
Schistosoma mansoni neuropeptide receptor 0.0195 0.1347 0.1746
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0157 0.0792
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0029 0.0088
Trypanosoma brucei Histone methylation protein DOT1, putative 0.0051 0.025 0.0247
Echinococcus multilocularis g-protein coupled receptor 0.0195 0.1347 0.1347
Entamoeba histolytica hypothetical protein 0.0043 0.0195 0.1003
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0122 0.079 0.4293
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0249 0.0323
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0069 0.0386 0.0386
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0608 0.0608
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0195 0.1347 0.1347
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.004 0.0197
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0159 0.1074 0.1074
Echinococcus granulosus geminin 0.1034 0.7714 0.7714
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0195 0.1347 0.1347
Schistosoma mansoni growth hormone secretagogue receptor 0.0195 0.1347 0.1746
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0029 0.0088
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0021 0.0022 0.0022
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0029 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0029 0.0082
Schistosoma mansoni biogenic amine receptor 0.0195 0.1347 0.1746
Echinococcus granulosus rho-associated protein kinase 1 0.0147 0.0982 0.0982
Brugia malayi RE15519p 0.0195 0.1347 0.1347
Onchocerca volvulus 0.0195 0.1347 0.8058
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.066 0.3584
Echinococcus granulosus serotonin receptor 0.0195 0.1347 0.1347
Giardia lamblia Kinase, CMGC MAPK 0.0105 0.066 0.615
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.01 0.01
Leishmania major S-adenosylhomocysteine hydrolase 0.0259 0.1835 0.1832
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Echinococcus granulosus neuropeptide s receptor 0.0195 0.1347 0.1347
Trypanosoma cruzi arginine N-methyltransferase, putative 0.019 0.1311 0.1308
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0196 0.1048
Trichomonas vaginalis ribokinase, putative 0.0019 0.0013 0.0051
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Onchocerca volvulus 0.0195 0.1347 0.8058
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0054 0.0277 0.0274
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0195 0.1347 0.1347
Onchocerca volvulus 0.0195 0.1347 0.8058
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0016
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0195 0.0195
Brugia malayi Ribokinase 0.0019 0.0013 0.0013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0019 0.003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0217 0.0217
Brugia malayi G-protein coupled receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0043 0.0196 0.0196
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0029 0.0029
Mycobacterium tuberculosis Conserved protein 0.0043 0.0196 0.0931
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0982 0.1273
Leishmania major adenosine kinase-like protein 0.0019 0.0013 0.0009
Loa Loa (eye worm) AGC/PKA protein kinase 0.0159 0.1074 0.1074
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0036 0.0036
Echinococcus multilocularis S adenosylmethionine decarboxylase proenzyme 0.1335 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Brugia malayi Adenosine kinase-like 0.0171 0.1161 0.1161
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0196 0.1002
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0029 0.0025
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.066 0.0657
Schistosoma mansoni biogenic amine receptor 0.0195 0.1347 0.1746
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0055 0.0055
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0157 0.0157
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0083 0.0454
Entamoeba histolytica adenosylhomocysteinase, putative 0.0259 0.1835 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0195 0.1347 0.8058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.1347 0.1746
Echinococcus multilocularis dna polymerase eta 0.0038 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0019 0.003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0196 0.0196
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0159 0.1074 0.1074
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0156 0.105 0.105
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0054 0.0277 0.0274
Leishmania major DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0051 0.025 0.0247
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0159 0.1074 0.2236
Echinococcus granulosus biogenic amine 5HT receptor 0.0195 0.1347 0.1347
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0413 0.0413
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0072 0.0093
Echinococcus granulosus neuropeptide Y receptor 0.0195 0.1347 0.1347
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0012 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0029 0.0082
Loa Loa (eye worm) hypothetical protein 0.0372 0.269 0.269
Loa Loa (eye worm) hypothetical protein 0.0029 0.0083 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0029 0.0082
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0259 0.1835 1
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0019 0.0013 0.0013
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0012 0.0012
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0195 0.1347 0.1347
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0157 0.0203
Echinococcus granulosus methyl CpG binding domain protein 2 0.0021 0.0022 0.0022
Trypanosoma brucei protein kinase, putative 0.0105 0.066 0.0657
Schistosoma mansoni hypothetical protein 0.0069 0.0386 0.0501
Onchocerca volvulus 0.0195 0.1347 0.8058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0277 0.1495
Schistosoma mansoni hypothetical protein 0.0195 0.1347 0.1746
Brugia malayi Histone-lysine N-methyltransferase, H3 lysine-79 specific 0.0399 0.2897 0.2897
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0051
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0083 0.0383
Echinococcus granulosus protein arginine N methyltransferase 8 0.0122 0.079 0.079
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0372 0.269 0.269
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0157 0.0836
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0012 0.0012
Echinococcus multilocularis mitogen activated protein kinase 0.0105 0.066 0.066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.1347 0.1746
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0029 0.0082
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0012 0.0012
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0012 0.0012
Onchocerca volvulus 0.0195 0.1347 0.8058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0019 0.003
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0027 0.0027
Trypanosoma cruzi adenosine kinase, putative 0.0019 0.0013 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0083 0.0383
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0122 0.079 0.4304
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0373 0.0373
Trichomonas vaginalis set domain proteins, putative 0.0237 0.1668 0.9089
Echinococcus multilocularis g protein coupled receptor 0.0195 0.1347 0.1347
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.01 0.01
Schistosoma mansoni myosin xvIII 0.0195 0.1347 0.1746
Loa Loa (eye worm) hypothetical protein 0.0049 0.0239 0.0239
Schistosoma mansoni DNA polymerase eta 0.0038 0.0157 0.0203
Brugia malayi G protein-coupled receptor 0.0195 0.1347 0.1347
Leishmania major putative PfkB family sugar kinase 0.0019 0.0013 0.0009
Trypanosoma cruzi arginine N-methyltransferase, putative 0.019 0.1311 0.1308
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0157 0.0789
Trypanosoma brucei ribokinase, putative 0.0019 0.0013 0.0009
Leishmania major cytochrome p450-like protein 0.0022 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0012 0.0012
Echinococcus granulosus tm gpcr rhodopsin 0.0195 0.1347 0.1347
Echinococcus granulosus methyltransferase protein 5 0.0069 0.0386 0.0386
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0029 0.0088
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0195 0.1347 0.1347
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0196 0.0931
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0036 0.0036
Brugia malayi Protein arginine N-methyltransferase 0.0069 0.0386 0.0386
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0277 0.1495
Echinococcus multilocularis 0.0022 0.0029 0.0029
Schistosoma mansoni opsin-like receptor 0.0195 0.1347 0.1746
Echinococcus multilocularis high affinity choline transporter 1 0.0351 0.2532 0.2532
Entamoeba histolytica hypothetical protein 0.0043 0.0195 0.1003
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.6194 0.8029
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0029 0.0088
Leishmania major tagatose-6-phosphate kinase-like protein 0.0019 0.0013 0.0009
Onchocerca volvulus 0.0195 0.1347 0.8058
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0195 0.1347 0.1746
Leishmania major arginine N-methyltransferase, type I 0.0069 0.0386 0.0383
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.01 0.01
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0195 0.1347 0.1347
Echinococcus multilocularis histone h3 methyltransferase 0.0399 0.2897 0.2897
Echinococcus granulosus g protein coupled receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0105 0.066 0.0657
Leishmania major S-adenosylmethionine decarboxylase 0.1335 1 1
Mycobacterium tuberculosis Conserved protein 0.0043 0.0196 0.0931
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0196 0.0196
Brugia malayi hypothetical protein 0.0019 0.0013 0.0013
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0083 0.0383
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0012 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0093 0.012
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0195 0.1347 0.1347
Echinococcus multilocularis neuropeptides capa receptor 0.0195 0.1347 0.1347
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.1347 0.1746
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0351 0.2532 0.2532
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Schistosoma mansoni amine GPCR 0.0195 0.1347 0.1746
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0069 0.0386 0.0386
Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase 0.065 0.4802 1
Giardia lamblia Ribokinase 0.0019 0.0013 0.0121
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0012 0.0016
Trichomonas vaginalis ribokinase, putative 0.0019 0.0013 0.0051
Schistosoma mansoni amine GPCR 0.0195 0.1347 0.1746
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0043 0.0193 0.019
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0029 0.0082
Echinococcus granulosus allatostatin A receptor 0.0195 0.1347 0.1347
Onchocerca volvulus 0.0237 0.1668 1
Onchocerca volvulus 0.0151 0.1013 0.6042
Echinococcus granulosus microtubule associated protein 2 0.0833 0.6194 0.6194
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0196 0.1048
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0029 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Trypanosoma brucei ribokinase, putative 0.0019 0.0013 0.0009
Brugia malayi Dopamine receptor protein 2 0.0195 0.1347 0.1347
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0372 0.269 0.2688
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0105 0.066 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0193 0.1035
Trypanosoma brucei S-adenosylmethionine decarboxylase proenzyme, putative 0.1335 1 1
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0069 0.0386 0.0383
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0259 0.1835 0.929
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0069 0.0386 0.0383
Echinococcus multilocularis neuropeptides capa receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) adenosylhomocysteinase 0.0259 0.1835 0.1835
Echinococcus granulosus neuropeptide receptor A26 0.0195 0.1347 0.1347
Echinococcus granulosus hypothetical protein 0.0195 0.1347 0.1347
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0195 0.1347 0.1746
Echinococcus multilocularis orexin receptor type 2 0.0195 0.1347 0.1347
Trypanosoma cruzi histone-lysine N-methyltransferase, putative 0.0051 0.025 0.0247
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0029 0.0088
Toxoplasma gondii adenosylhomocysteinase, putative 0.0259 0.1835 1
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0196 0.0192
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0029 0.0082
Schistosoma mansoni hypothetical protein 0.1034 0.7714 1
Echinococcus granulosus dro:myosuppressin receptor 0.0195 0.1347 0.1347
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0157 0.0836
Echinococcus granulosus neuropeptide receptor 0.0195 0.1347 0.1347
Echinococcus multilocularis neuropeptide receptor A26 0.0195 0.1347 0.1347
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0157 0.0733
Brugia malayi hypothetical protein 0.019 0.1311 0.1311
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0195 0.1347 0.1347
Brugia malayi Latrophilin receptor protein 2 0.0031 0.01 0.01
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0029 0.0088
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0196 0.0253
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0083 0.0083
Trichomonas vaginalis ribokinase, putative 0.0019 0.0013 0.0051
Echinococcus granulosus sex peptide receptor 0.0195 0.1347 0.1347
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0122 0.079 0.1024
Brugia malayi Pre-SET motif family protein 0.003 0.0093 0.0093
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0083 0.0079
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0069 0.0386 0.2089
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0016
Echinococcus granulosus tachykinin peptides receptor 99D 0.0195 0.1347 0.1347
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0036 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Brugia malayi Melatonin receptor type 1A 0.0195 0.1347 0.1347
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0157 0.0153
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0195 0.1347 0.1347
Trypanosoma brucei unspecified product 0.0026 0.0066 0.0063
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0036 0.0046
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0195 0.1347 0.1347
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0195 0.1347 0.1347
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0819 0.6086 0.6086
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0029 0.0082
Echinococcus granulosus tm gpcr rhodopsin 0.0195 0.1347 0.1347
Echinococcus granulosus somatostatin receptor 0.0195 0.1347 0.1347
Mycobacterium leprae Probable lipase LipE 0.0043 0.0196 0.1002
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0196 0.0192
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0157 0.0153
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0195 0.1347 0.1347
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0083 0.0386
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0152 0.0316
Schistosoma mansoni adenosylhomocysteinase 0.0161 0.1084 0.1406
Echinococcus multilocularis neuropeptide receptor 0.0195 0.1347 0.1347
Echinococcus multilocularis neuropeptide receptor 0.0195 0.1347 0.1347
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0196 0.1048
Brugia malayi beta-lactamase family protein 0.0043 0.0196 0.0196
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0259 0.1835 1
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.019 0.1311 0.7122
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0172 0.0919
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0069 0.0386 0.0383
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0069 0.0386 0.205
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0195 0.1347 0.1746
Trypanosoma cruzi ISWI complex protein 0.0018 0.0006 0.0002
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0054 0.0277 0.0274
Echinococcus multilocularis ribokinase 0.0019 0.0013 0.0013
Schistosoma mansoni zinc finger protein 0.0024 0.0045 0.0058
Loa Loa (eye worm) G-protein coupled receptor 0.0195 0.1347 0.1347
Brugia malayi Protein kinase domain containing protein 0.0451 0.3289 0.3289
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0196 0.1002
Loa Loa (eye worm) CYP4Cod1 0.0039 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Schistosoma mansoni amine GPCR 0.0195 0.1347 0.1746
Loa Loa (eye worm) cytochrome P450 0.0022 0.0029 0.0029
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0259 0.1835 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0196 0.0931
Schistosoma mansoni hypothetical protein 0.0025 0.0055 0.0071
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0039 0.0159 0.0159
Echinococcus multilocularis serotonin receptor 0.0195 0.1347 0.1347
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0192 0.1026
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0157 0.0789
Schistosoma mansoni neuropeptide F-like receptor 0.0195 0.1347 0.1746
Echinococcus granulosus 7tm_1 domain containing protein 0.0195 0.1347 0.1347
Brugia malayi GnHR receptor homolog 0.0195 0.1347 0.1347
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0012 0.0012
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0048
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0259 0.1835 0.1832
Brugia malayi hypothetical protein 0.0043 0.0195 0.0195
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.1074 0.1392
Loa Loa (eye worm) beta-lactamase 0.0043 0.0196 0.0196
Brugia malayi Bromodomain containing protein 0.0046 0.0217 0.0217
Echinococcus multilocularis geminin 0.1034 0.7714 0.7714
Mycobacterium tuberculosis Conserved protein 0.0043 0.0196 0.0931
Echinococcus granulosus sodium:myo inositol cotransporter 0.0039 0.0159 0.0159
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0054 0.0277 0.0274
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0029 0.0088
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0159 0.1074 0.107
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0083 0.0356
Echinococcus multilocularis serotonin receptor 0.0195 0.1347 0.1347
Trypanosoma cruzi Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0051 0.025 0.0247
Trypanosoma cruzi adenosine kinase, putative 0.0171 0.1161 0.1158
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0029 0.0088
Entamoeba histolytica kinase, PfkB family 0.0019 0.0013 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0093 0.0093
Schistosoma mansoni adenosylhomocysteinase 0.0259 0.1835 0.2379
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0172 0.0919
Onchocerca volvulus 0.0043 0.0196 0.1103
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0195 0.1347 0.1347
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0054 0.0277 0.0277
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0019 0.0013 0.0003
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0083 0.0386
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.1975 1
Schistosoma mansoni biogenic amine receptor 0.0195 0.1347 0.1746
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0122 0.079 0.079
Onchocerca volvulus 0.0195 0.1347 0.8058
Brugia malayi neuropeptide F receptor 0.0195 0.1347 0.1347
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0196 0.0931
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Onchocerca volvulus 0.0043 0.0196 0.1103
Echinococcus multilocularis neuropeptide Y receptor 0.0195 0.1347 0.1347
Brugia malayi hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Echinococcus granulosus expressed protein 0.0377 0.2729 0.2729
Echinococcus multilocularis somatostatin receptor 0.0195 0.1347 0.1347
Brugia malayi Cytochrome P450 family protein 0.006 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0112 0.059
Leishmania major hypothetical protein, conserved 0.0043 0.0196 0.0192
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus granulosus alpha 1A adrenergic receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0159 0.1074 0.1074
Schistosoma mansoni neuropeptide F-like receptor 0.0195 0.1347 0.1746
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Entamoeba histolytica PH domain containing protein kinase, putative 0.0159 0.1074 0.5821
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0195 0.1347 0.1746
Brugia malayi neuropeptide F receptor 0.0195 0.1347 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0193 0.1035
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0022 0.0028
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0608 0.0608
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0093 0.0505
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0195 0.1347 0.1347
Echinococcus multilocularis neuropeptide Y receptor 0.0195 0.1347 0.1347
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0084 0.0084
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0029 0.0086 0.0122
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0259 0.1835 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0043 0.0196 0.0196
Echinococcus granulosus high affinity choline transporter 1 0.0351 0.2532 0.2532
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.004 0.0036
Echinococcus granulosus g protein coupled receptor 0.0195 0.1347 0.1347
Onchocerca volvulus 0.0195 0.1347 0.8058
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0054 0.0277 0.1454
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0012 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.066 0.3584
Onchocerca volvulus 0.0195 0.1347 0.8058
Trypanosoma brucei ISWI complex protein 0.0018 0.0006 0.0002
Schistosoma mansoni hypothetical protein 0.0195 0.1347 0.1746
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0164 0.0164
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0196 0.0931
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0196 0.0196
Plasmodium falciparum adenosylhomocysteinase 0.0259 0.1835 0.3822
Schistosoma mansoni bromodomain containing protein 0.0076 0.0446 0.0578
Echinococcus granulosus neuropeptide FF receptor 2 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0122 0.079 0.4293
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.1347 0.1746
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Leishmania major ribokinase, putative 0.0019 0.0013 0.0009
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0195 0.1347 0.1347
Echinococcus granulosus GPCR family 2 0.0031 0.01 0.01
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0012 0.0012
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0029 0.0082
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0019 0.003
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0054 0.0277 0.0274
Brugia malayi Cytochrome P450 family protein 0.0039 0.0164 0.0164
Echinococcus granulosus orexin receptor type 2 0.0195 0.1347 0.1347
Trypanosoma cruzi cytochrome P450, putative 0.0039 0.0164 0.016
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0029 0.0082
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0157 0.0153
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0122 0.079 0.4293
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0048
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0157 0.0157
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0029 0.0082
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0012 0.0016
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0196 0.1048
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0069 0.0386 0.2089
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0028 0.0058
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0192 0.1026
Echinococcus granulosus mitogen activated protein kinase 0.0105 0.066 0.066
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0195 0.1347 0.1347
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.1347 0.1746
Echinococcus granulosus neuropeptides capa receptor 0.0195 0.1347 0.1347
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.004 0.0036
Echinococcus multilocularis G-protein coupled receptor, putative 0.0195 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0051 0.0249 0.0249
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0029 0.0088
Onchocerca volvulus 0.0144 0.0958 0.5711
Brugia malayi Serotonin receptor 0.0195 0.1347 0.1347

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.8492 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 0.8913 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 2.2387 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (binding) = 2.5119 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 5.8479 uM PUBCHEM_BIOASSAY: Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2660, AID2666, AID2667, AID2668, AID2681, AID504465] ChEMBL. No reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 7.3078 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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