Detailed information for compound 902327

Basic information

Technical information
  • TDR Targets ID: 902327
  • Name: 3-butyl-10-(4-chlorophenyl)pyrimido[6,5-b]qui noline-2,4-dione
  • MW: 379.84 | Formula: C21H18ClN3O2
  • H donors: 0 H acceptors: 2 LogP: 4.55 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCn1c(=O)nc2c(c1=O)cc1c(n2c2ccc(cc2)Cl)cccc1
  • InChi: 1S/C21H18ClN3O2/c1-2-3-12-24-20(26)17-13-14-6-4-5-7-18(14)25(19(17)23-21(24)27)16-10-8-15(22)9-11-16/h4-11,13H,2-3,12H2,1H3
  • InChiKey: NECRYMIQCSTGMC-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 3-butyl-10-(4-chlorophenyl)pyrimido[6,5-b]quinoline-2,4-quinone
  • ChemDiv1_022015
  • ZINC02124415
  • STOCK3S-73741
  • AM-900/13371014
  • 3-Butyl-10-(4-chloro-phenyl)-10H-pyrimido[4,5-b]quinoline-2,4-dione
  • MLS000590055
  • SMR000219287
  • Oprea1_092560

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references
Equus caballus Ferritin light chain Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4E Starlite/ChEMBL No references
Macaaca fascicularis T-complex protein 1 subunit beta Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta Get druggable targets OG5_127730 All targets in OG5_127730
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb Get druggable targets OG5_127730 All targets in OG5_127730
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K09494 T-complex protein 1 subunit beta, putative Get druggable targets OG5_127730 All targets in OG5_127730
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major T-complex protein 1, beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis T-complex protein 1, beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Toxoplasma gondii t-complex protein beta subunit Get druggable targets OG5_127730 All targets in OG5_127730
Plasmodium falciparum T-complex protein 1 subunit beta Get druggable targets OG5_127730 All targets in OG5_127730
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi T-complex protein 1, beta subunit Get druggable targets OG5_127730 All targets in OG5_127730
Plasmodium vivax T-complex protein 1 subunit beta, putative Get druggable targets OG5_127730 All targets in OG5_127730
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Babesia bovis T-complex protein beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae CCT2 (YIL142W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol Get druggable targets OG5_127730 All targets in OG5_127730
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi T-complex protein 1 subunit beta, putative Get druggable targets OG5_127730 All targets in OG5_127730
Candida albicans similar to S. cerevisiae CCT2 (YIL142W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol Get druggable targets OG5_127730 All targets in OG5_127730
Brugia malayi T-complex protein 1, beta subunit Get druggable targets OG5_127730 All targets in OG5_127730
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica T-complex protein 1 beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Cryptosporidium parvum GroEL-like chaperone (ATpase); T-complex protein 1 Get druggable targets OG5_127730 All targets in OG5_127730
Plasmodium yoelii putative T-complex protein beta subunit Get druggable targets OG5_127730 All targets in OG5_127730
Loa Loa (eye worm) T-complex protein 1 Get druggable targets OG5_127730 All targets in OG5_127730
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum TCP-1/cpn60 family chaperonin, putative Get druggable targets OG5_127730 All targets in OG5_127730
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis chaperonin-60kD, ch60, putative Get druggable targets OG5_127730 All targets in OG5_127730
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia TCP-1 chaperonin subunit beta Get druggable targets OG5_127730 All targets in OG5_127730
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis chaperonin, putative Get druggable targets OG5_127730 All targets in OG5_127730
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi T-complex protein 1, beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani T-complex protein 1, beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum T-complex protein 1, beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei T-complex protein 1, beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Cryptosporidium hominis TCP-1/cpn60 chaperonin-related protein Get druggable targets OG5_127730 All targets in OG5_127730
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) Get druggable targets OG5_127730 All targets in OG5_127730
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb Get druggable targets OG5_127730 All targets in OG5_127730
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva T-complex protein 1, beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Trypanosoma brucei gambiense T-complex protein 1, beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei T-complex protein 1 subunit beta, putative Get druggable targets OG5_127730 All targets in OG5_127730
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana T-complex protein 1, beta subunit, putative Get druggable targets OG5_127730 All targets in OG5_127730
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb Get druggable targets OG5_127730 All targets in OG5_127730
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania braziliensis chaperonin alpha subunit, putative T-complex protein 1 subunit beta   535 aa 529 aa 33.5 %
Leishmania mexicana T-complex protein 1, gamma subunit, putative T-complex protein 1 subunit beta   535 aa 540 aa 29.6 %
Trichomonas vaginalis chaperonin, putative T-complex protein 1 subunit beta   535 aa 545 aa 29.7 %
Trypanosoma congolense T-complex protein 1, zeta subunit, putative T-complex protein 1 subunit beta   535 aa 549 aa 26.0 %
Plasmodium vivax T-complex protein 1 subunit alpha, putative T-complex protein 1 subunit beta   535 aa 540 aa 34.1 %
Loa Loa (eye worm) CCT-5 protein T-complex protein 1 subunit beta   535 aa 521 aa 31.3 %
Cryptosporidium hominis CCT chaperonin gamma subunit T-complex protein 1 subunit beta   535 aa 536 aa 28.4 %
Dictyostelium discoideum chaperonin containing TCP1 alpha subunit T-complex protein 1 subunit beta   535 aa 535 aa 33.3 %
Plasmodium knowlesi T-complex protein 1 subunit eta, putative T-complex protein 1 subunit beta   535 aa 530 aa 34.7 %
Trypanosoma congolense t- complex protein 1 (eta subunit), putative T-complex protein 1 subunit beta   535 aa 518 aa 34.9 %
Schistosoma mansoni chaperonin containing t-complex protein 1 zeta subunit tcpz T-complex protein 1 subunit beta   535 aa 544 aa 26.3 %
Leishmania infantum chaperonin alpha subunit, putative T-complex protein 1 subunit beta   535 aa 529 aa 33.5 %
Candida albicans similar to S. cerevisiae CCT7 (YJL111W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 523 aa 35.4 %
Plasmodium vivax T-complex protein 1 subunit theta, putative T-complex protein 1 subunit beta   535 aa 538 aa 27.3 %
Leishmania major chaperonin containing t-complex protein, putative T-complex protein 1 subunit beta   535 aa 529 aa 31.2 %
Babesia bovis HSP60 fold T-complex protein 1, putative T-complex protein 1 subunit beta   535 aa 497 aa 28.0 %
Trypanosoma cruzi chaperonin TCP20, putative T-complex protein 1 subunit beta   535 aa 547 aa 26.0 %
Cryptosporidium hominis T-complex protein 1 T-complex protein 1 subunit beta   535 aa 527 aa 36.2 %
Leishmania major T-complex protein 1, gamma subunit, putative T-complex protein 1 subunit beta   535 aa 540 aa 29.3 %
Trichomonas vaginalis chaperonin containing t-complex protein 1, eta subunit, tcph, putative T-complex protein 1 subunit beta   535 aa 549 aa 35.7 %
Neospora caninum Thermosome subunit, related T-complex protein 1 subunit beta   535 aa 527 aa 31.3 %
Babesia bovis T-complex protein 1 zeta subunit T-complex protein 1 subunit beta   535 aa 532 aa 26.7 %
Giardia lamblia TCP-1 chaperonin subunit epsilon T-complex protein 1 subunit beta   535 aa 535 aa 31.6 %
Cryptosporidium parvum T complex chaperonin T-complex protein 1 subunit beta   535 aa 525 aa 33.1 %
Schistosoma japonicum ko:K09496 T-complex protein 1 subunit delta, putative T-complex protein 1 subunit beta   535 aa 533 aa 32.1 %
Onchocerca volvulus T-complex protein 1 subunit beta   535 aa 511 aa 26.2 %
Entamoeba histolytica T-complex protein 1 theta subunit, putative T-complex protein 1 subunit beta   535 aa 511 aa 26.2 %
Candida albicans similar to S. cerevisiae CCT5 (YJR064W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 524 aa 34.2 %
Leishmania infantum T-complex protein 1, theta subunit, putative,chaperonin, putative T-complex protein 1 subunit beta   535 aa 507 aa 28.4 %
Plasmodium yoelii CCT chaperonin gamma subunit T-complex protein 1 subunit beta   535 aa 523 aa 30.0 %
Candida albicans similar to S. cerevisiae TCP1 (YDR212W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 548 aa 32.8 %
Neospora caninum TCP-1/cpn60 family chaperonin, putative T-complex protein 1 subunit beta   535 aa 516 aa 26.2 %
Trypanosoma cruzi chaperonin alpha subunit, putative T-complex protein 1 subunit beta   535 aa 533 aa 33.8 %
Entamoeba histolytica T-complex protein 1 gamma subunit, putative T-complex protein 1 subunit beta   535 aa 536 aa 29.9 %
Plasmodium knowlesi T-complex protein 1 subunit alpha, putative T-complex protein 1 subunit beta   535 aa 540 aa 33.7 %
Plasmodium berghei T-complex protein 1 subunit zeta, putative T-complex protein 1 subunit beta   535 aa 537 aa 23.5 %
Onchocerca volvulus T-complex protein 1 subunit beta   535 aa 542 aa 27.7 %
Schistosoma mansoni chaperonin containing t-complex protein 1 eta subunit tcph T-complex protein 1 subunit beta   535 aa 536 aa 32.8 %
Giardia lamblia TCP-1 chaperonin subunit gamma T-complex protein 1 subunit beta   535 aa 561 aa 29.8 %
Leishmania donovani chaperonin alpha subunit, putative T-complex protein 1 subunit beta   535 aa 529 aa 33.5 %
Entamoeba histolytica chaperonin-containing TCP-1, zeta subunit, putative T-complex protein 1 subunit beta   535 aa 550 aa 23.5 %
Leishmania mexicana T-complex protein 1, eta subunit, putative T-complex protein 1 subunit beta   535 aa 519 aa 35.1 %
Drosophila melanogaster T-complex Chaperonin 5 T-complex protein 1 subunit beta   535 aa 506 aa 34.6 %
Toxoplasma gondii T-complex protein 1, epsilon subunit (TCP-1-epsilon), putative T-complex protein 1 subunit beta   535 aa 529 aa 31.8 %
Trypanosoma cruzi T-complex protein 1, theta subunit, putative T-complex protein 1 subunit beta   535 aa 509 aa 29.5 %
Trichomonas vaginalis chaperonin containing t-complex protein 1, gamma subunit, tcpg, putative T-complex protein 1 subunit beta   535 aa 540 aa 34.1 %
Echinococcus multilocularis T complex protein 1 subunit theta T-complex protein 1 subunit beta   535 aa 516 aa 27.1 %
Dictyostelium discoideum hypothetical protein T-complex protein 1 subunit beta   535 aa 528 aa 20.8 %
Theileria parva T-complex protein 1, epsilon subunit, putative T-complex protein 1 subunit beta   535 aa 522 aa 32.4 %
Candida albicans similar to S. cerevisiae CCT6 (YDR188W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 541 aa 27.4 %
Leishmania donovani chaperonin containing t-complex protein, putative T-complex protein 1 subunit beta   535 aa 529 aa 31.8 %
Candida albicans similar to S. cerevisiae CCT7 (YJL111W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 523 aa 35.4 %
Candida albicans similar to S. cerevisiae CCT8 (YJL008C) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 497 aa 27.2 %
Plasmodium berghei T-complex protein 1 subunit alpha, putative T-complex protein 1 subunit beta   535 aa 539 aa 34.1 %
Mycobacterium tuberculosis 60 kDa chaperonin 2 GroEL2 (protein CPN60-2) (GroEL protein 2) (65 kDa antigen) (heat shock protein 65) (cell wall protein A) (a T-complex protein 1 subunit beta   535 aa 565 aa 23.5 %
Trypanosoma brucei gambiense T-complex protein 1, epsilon subunit, putative T-complex protein 1 subunit beta   535 aa 534 aa 31.8 %
Loa Loa (eye worm) T-complex protein 1 T-complex protein 1 subunit beta   535 aa 533 aa 28.3 %
Echinococcus granulosus T complex protein 1 subunit theta T-complex protein 1 subunit beta   535 aa 517 aa 27.1 %
Schistosoma japonicum ko:K09498 T-complex protein 1 subunit zeta, putative T-complex protein 1 subunit beta   535 aa 552 aa 25.7 %
Leishmania mexicana chaperonin TCP20, putative T-complex protein 1 subunit beta   535 aa 538 aa 26.8 %
Trypanosoma brucei gambiense T-complex protein 1, theta subunit, putative,CCT-theta, putative T-complex protein 1 subunit beta   535 aa 510 aa 29.4 %
Candida albicans similar to S. cerevisiae CCT5 (YJR064W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 524 aa 34.2 %
Trypanosoma congolense T-complex protein 1, theta subunit, putative T-complex protein 1 subunit beta   535 aa 510 aa 28.6 %
Echinococcus multilocularis t complex protein 1 subunit gamma T-complex protein 1 subunit beta   535 aa 556 aa 30.6 %
Babesia bovis TCP-1/cpn60 chaperonin family protein T-complex protein 1 subunit beta   535 aa 538 aa 30.5 %
Leishmania major T-complex protein 1, theta subunit, putative,chaperonin, putative T-complex protein 1 subunit beta   535 aa 507 aa 28.8 %
Leishmania infantum T-complex protein 1, eta subunit, putative T-complex protein 1 subunit beta   535 aa 519 aa 34.7 %
Toxoplasma gondii CCT chaperonin gamma subunit T-complex protein 1 subunit beta   535 aa 531 aa 29.2 %
Entamoeba histolytica T-complex protein 1, alpha subunit, putative T-complex protein 1 subunit beta   535 aa 528 aa 31.6 %
Plasmodium berghei T-complex protein 1 subunit gamma, putative T-complex protein 1 subunit beta   535 aa 523 aa 30.2 %
Dictyostelium discoideum hypothetical protein T-complex protein 1 subunit beta   535 aa 549 aa 20.6 %
Trypanosoma congolense T-complex protein 1, gamma subunit, putative T-complex protein 1 subunit beta   535 aa 540 aa 29.4 %
Plasmodium yoelii T-complex protein 1 epsilon subunit T-complex protein 1 subunit beta   535 aa 508 aa 32.9 %
Cryptosporidium parvum t-complex protein 1, alpha subunit T-complex protein 1 subunit beta   535 aa 544 aa 33.1 %
Schistosoma japonicum Ferritin, putative Ferritin light chain   175 aa 144 aa 24.3 %
Leishmania major chaperonin TCP20, putative T-complex protein 1 subunit beta   535 aa 543 aa 26.3 %
Trichomonas vaginalis chaperonin containing t-complex protein 1, eta subunit, tcph, putative T-complex protein 1 subunit beta   535 aa 517 aa 30.4 %
Plasmodium knowlesi T-complex protein 1 subunit theta, putative T-complex protein 1 subunit beta   535 aa 538 aa 27.1 %
Echinococcus granulosus T complex protein 1 subunit eta T-complex protein 1 subunit beta   535 aa 535 aa 34.0 %
Echinococcus multilocularis T complex protein 1 subunit zeta T-complex protein 1 subunit beta   535 aa 544 aa 26.7 %
Plasmodium berghei T-complex protein 1 subunit eta, putative T-complex protein 1 subunit beta   535 aa 530 aa 34.5 %
Leishmania mexicana chaperonin alpha subunit, putative T-complex protein 1 subunit beta   535 aa 529 aa 33.3 %
Leishmania braziliensis T-complex protein 1, delta subunit, putative T-complex protein 1 subunit beta   535 aa 530 aa 29.1 %
Dictyostelium discoideum chaperonin containing TCP1 theta subunit T-complex protein 1 subunit beta   535 aa 501 aa 27.1 %
Plasmodium yoelii putative chaperonin T-complex protein 1 subunit beta   535 aa 497 aa 22.7 %
Trichomonas vaginalis chaperonin, putative T-complex protein 1 subunit beta   535 aa 575 aa 23.1 %
Echinococcus granulosus chaperonin containing TCP1 subunit 5 epsilon T-complex protein 1 subunit beta   535 aa 513 aa 33.1 %
Leishmania major T-complex protein 1, eta subunit, putative T-complex protein 1 subunit beta   535 aa 519 aa 34.5 %
Trypanosoma brucei gambiense T-complex protein 1, delta subunit, putative T-complex protein 1 subunit beta   535 aa 535 aa 29.7 %
Toxoplasma gondii T-complex protein 1 subunit alpha, putative T-complex protein 1 subunit beta   535 aa 540 aa 34.8 %
Trypanosoma cruzi chaperonin/T-complex protein 1 gamma subunit, putative T-complex protein 1 subunit beta   535 aa 530 aa 30.9 %
Brugia malayi T-complex protein 1, alpha subunit T-complex protein 1 subunit beta   535 aa 534 aa 35.6 %
Trypanosoma cruzi T-complex protein 1, delta subunit, putative T-complex protein 1 subunit beta   535 aa 519 aa 29.7 %
Loa Loa (eye worm) T-complex protein 1 T-complex protein 1 subunit beta   535 aa 547 aa 32.7 %
Brugia malayi T-complex protein 1, gamma subunit T-complex protein 1 subunit beta   535 aa 529 aa 28.4 %
Trypanosoma cruzi chaperonin containing t-complex protein, putative T-complex protein 1 subunit beta   535 aa 528 aa 33.0 %
Trypanosoma brucei T-complex protein 1, epsilon subunit, putative T-complex protein 1 subunit beta   535 aa 534 aa 31.8 %
Leishmania braziliensis chaperonin TCP20, putative T-complex protein 1 subunit beta   535 aa 542 aa 26.2 %
Trypanosoma brucei gambiense T-complex protein 1, alpha subunit, putative T-complex protein 1 subunit beta   535 aa 524 aa 34.2 %
Onchocerca volvulus T-complex protein 1 subunit beta   535 aa 550 aa 32.9 %
Dictyostelium discoideum chaperonin containing TCP1 epsilon subunit T-complex protein 1 subunit beta   535 aa 520 aa 34.4 %
Entamoeba histolytica hypothetical protein T-complex protein 1 subunit beta   535 aa 516 aa 22.5 %
Cryptosporidium hominis chaperonin containing TCP-1 delta subunit T-complex protein 1 subunit beta   535 aa 534 aa 30.9 %
Plasmodium knowlesi T-complex protein 1 subunit zeta, putative T-complex protein 1 subunit beta   535 aa 544 aa 23.5 %
Loa Loa (eye worm) T-complex protein 1 T-complex protein 1 subunit beta   535 aa 550 aa 32.0 %
Schistosoma japonicum ko:K09499 T-complex protein 1 subunit eta, putative T-complex protein 1 subunit beta   535 aa 536 aa 34.0 %
Trichomonas vaginalis chaperonin-60kD, ch60, putative T-complex protein 1 subunit beta   535 aa 538 aa 33.6 %
Dictyostelium discoideum chaperonin containing TCP1 eta subunit T-complex protein 1 subunit beta   535 aa 528 aa 33.5 %
Neospora caninum hypothetical protein T-complex protein 1 subunit beta   535 aa 531 aa 29.0 %
Trypanosoma brucei T-complex protein 1, theta subunit, putative T-complex protein 1 subunit beta   535 aa 510 aa 29.4 %
Onchocerca volvulus T-complex protein 1 subunit beta   535 aa 579 aa 23.1 %
Leishmania braziliensis chaperonin containing t-complex protein, putative T-complex protein 1 subunit beta   535 aa 534 aa 31.8 %
Giardia lamblia TCP-1 chaperonin subunit theta T-complex protein 1 subunit beta   535 aa 563 aa 25.2 %
Schistosoma mansoni chaperonin containing t-complex protein 1 gamma subunit tcpg T-complex protein 1 subunit beta   535 aa 552 aa 29.7 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Trypanosoma congolense T-complex protein 1, epsilon subunit, putative T-complex protein 1 subunit beta   535 aa 534 aa 32.2 %
Plasmodium yoelii chaperonin, 60 kDa T-complex protein 1 subunit beta   535 aa 530 aa 34.9 %
Plasmodium vivax T-complex protein 1 subunit zeta, putative T-complex protein 1 subunit beta   535 aa 539 aa 22.4 %
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Leishmania donovani T-complex protein 1, eta subunit, putative T-complex protein 1 subunit beta   535 aa 519 aa 34.7 %
Leishmania infantum chaperonin TCP20, putative T-complex protein 1 subunit beta   535 aa 543 aa 26.7 %
Trichomonas vaginalis rubisco subunit binding-protein alpha subunit, ruba, putative T-complex protein 1 subunit beta   535 aa 580 aa 23.3 %
Leishmania mexicana T-complex protein 1, delta subunit, putative T-complex protein 1 subunit beta   535 aa 528 aa 29.2 %
Leishmania donovani chaperonin TCP20, putative T-complex protein 1 subunit beta   535 aa 543 aa 26.5 %
Plasmodium vivax T-complex protein 1 subunit eta, putative T-complex protein 1 subunit beta   535 aa 530 aa 34.5 %
Leishmania braziliensis T-complex protein 1, gamma subunit, putative T-complex protein 1 subunit beta   535 aa 526 aa 30.0 %
Brugia malayi T-complex protein 1, eta subunit T-complex protein 1 subunit beta   535 aa 534 aa 33.1 %
Neospora caninum TCP-1/cpn60 family chaperonin, putative T-complex protein 1 subunit beta   535 aa 540 aa 34.4 %
Plasmodium vivax T-complex protein 1 subunit gamma, putative T-complex protein 1 subunit beta   535 aa 529 aa 31.2 %
Leishmania braziliensis T-complex protein 1, theta subunit, putative,chaperonin, putative T-complex protein 1 subunit beta   535 aa 507 aa 28.2 %
Echinococcus granulosus t complex protein 1 subunit gamma T-complex protein 1 subunit beta   535 aa 556 aa 30.6 %
Trypanosoma brucei T-complex protein 1, zeta subunit, putative T-complex protein 1 subunit beta   535 aa 548 aa 26.3 %
Plasmodium knowlesi T-complex protein 1 subunit gamma, putative T-complex protein 1 subunit beta   535 aa 526 aa 31.0 %
Trichomonas vaginalis chaperonin containing t-complex protein 1, beta subunit, tcpb, putative T-complex protein 1 subunit beta   535 aa 541 aa 35.5 %
Theileria parva T-complex protein 1, gamma subunit, putative T-complex protein 1 subunit beta   535 aa 543 aa 27.1 %
Theileria parva chaperonin 60 kDa, putative T-complex protein 1 subunit beta   535 aa 544 aa 26.1 %
Plasmodium falciparum T-complex protein 1 subunit alpha T-complex protein 1 subunit beta   535 aa 546 aa 34.4 %
Trypanosoma brucei T-complex protein 1, gamma subunit, putative T-complex protein 1 subunit beta   535 aa 543 aa 29.8 %
Trypanosoma brucei gambiense T-complex protein 1, gamma subunit, putative T-complex protein 1 subunit beta   535 aa 543 aa 29.8 %
Cryptosporidium parvum TCP-1/cpn60 chaperonin family, T-complex protein subunit 7 (eta) T-complex protein 1 subunit beta   535 aa 527 aa 36.2 %
Leishmania donovani T-complex protein 1, theta subunit, putative T-complex protein 1 subunit beta   535 aa 507 aa 28.2 %
Trypanosoma brucei T-complex protein 1, alpha subunit, putative T-complex protein 1 subunit beta   535 aa 524 aa 34.4 %
Cryptosporidium parvum putative t-complex protein 1, gamma subunit T-complex protein 1 subunit beta   535 aa 545 aa 28.3 %
Echinococcus multilocularis T complex protein 1 subunit zeta T-complex protein 1 subunit beta   535 aa 544 aa 26.7 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 43.9 %
Leishmania braziliensis T-complex protein 1, eta subunit, putative T-complex protein 1 subunit beta   535 aa 519 aa 34.7 %
Brugia malayi T-complex protein 1, epsilon subunit T-complex protein 1 subunit beta   535 aa 513 aa 31.4 %
Trypanosoma congolense T-complex protein 1, alpha subunit, putative T-complex protein 1 subunit beta   535 aa 525 aa 34.1 %
Cryptosporidium hominis CCTepsilon subunit T-complex protein 1 subunit beta   535 aa 525 aa 33.1 %
Plasmodium yoelii T-complex protein 1 T-complex protein 1 subunit beta   535 aa 534 aa 26.2 %
Trypanosoma brucei gambiense T-complex protein 1, zeta subunit, putative T-complex protein 1 subunit beta   535 aa 548 aa 26.3 %
Giardia lamblia TCP-1 chaperonin subunit alpha T-complex protein 1 subunit beta   535 aa 528 aa 32.6 %
Leishmania donovani T-complex protein 1, delta subunit, putative T-complex protein 1 subunit beta   535 aa 528 aa 29.0 %
Echinococcus multilocularis T complex protein 1 subunit eta T-complex protein 1 subunit beta   535 aa 535 aa 33.3 %
Echinococcus granulosus T complex protein 1 subunit zeta T-complex protein 1 subunit beta   535 aa 544 aa 26.5 %
Candida albicans similar to S. cerevisiae CCT6 (YDR188W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 541 aa 27.4 %
Cryptosporidium parvum putative T complex chaperonin T-complex protein 1 subunit beta   535 aa 546 aa 25.1 %
Neospora caninum TCP-1/cpn60 family chaperonin, putative T-complex protein 1 subunit beta   535 aa 546 aa 33.7 %
Brugia malayi T-complex protein 1 theta subunit T-complex protein 1 subunit beta   535 aa 502 aa 26.3 %
Schistosoma mansoni chaperonin containing t-complex protein 1 epsilon subunit tcpe T-complex protein 1 subunit beta   535 aa 505 aa 33.9 %
Entamoeba histolytica chaperonin containing TCP-1 epsilon subunit, putative T-complex protein 1 subunit beta   535 aa 508 aa 32.7 %
Trichomonas vaginalis chaperonin containing t-complex protein 1, epsilon subunit, tcpe, putative T-complex protein 1 subunit beta   535 aa 517 aa 30.4 %
Echinococcus multilocularis chaperonin containing TCP1, subunit 5 (epsilon) T-complex protein 1 subunit beta   535 aa 513 aa 33.1 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 142 aa 29.6 %
Schistosoma japonicum ko:K09493 T-complex protein 1 subunit alpha, putative T-complex protein 1 subunit beta   535 aa 585 aa 31.5 %
Toxoplasma gondii T-complex protein 1 eta subunit T-complex protein 1 subunit beta   535 aa 546 aa 33.9 %
Candida albicans similar to S. cerevisiae CCT4 (YDL143W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 546 aa 31.0 %
Trypanosoma congolense T-complex protein 1, delta subunit, putative T-complex protein 1 subunit beta   535 aa 521 aa 29.6 %
Trichomonas vaginalis chaperonin, putative T-complex protein 1 subunit beta   535 aa 531 aa 29.8 %
Echinococcus granulosus expressed protein Ferritin light chain   175 aa 146 aa 28.8 %
Echinococcus multilocularis expressed protein Ferritin light chain   175 aa 146 aa 30.1 %
Trypanosoma congolense T-complex protein 1, zeta subunit, putative T-complex protein 1 subunit beta   535 aa 549 aa 26.0 %
Trypanosoma brucei t- complex protein 1 (eta subunit), putative T-complex protein 1 subunit beta   535 aa 518 aa 34.6 %
Plasmodium falciparum T-complex protein 1 subunit zeta T-complex protein 1 subunit beta   535 aa 539 aa 23.4 %
Plasmodium falciparum T-complex protein 1 subunit eta T-complex protein 1 subunit beta   535 aa 542 aa 34.9 %
Leishmania major chaperonin alpha subunit, putative T-complex protein 1 subunit beta   535 aa 529 aa 33.1 %
Leishmania infantum T-complex protein 1, delta subunit, putative T-complex protein 1 subunit beta   535 aa 528 aa 29.0 %
Onchocerca volvulus Integrator complex subunit 3 homolog T-complex protein 1 subunit beta   535 aa 534 aa 35.8 %
Trypanosoma brucei gambiense T-complex protein 1, eta subunit, putative,t- complex protein 1 (eta subunit), putative T-complex protein 1 subunit beta   535 aa 518 aa 34.4 %
Plasmodium berghei T-complex protein 1 subunit theta, putative T-complex protein 1 subunit beta   535 aa 526 aa 25.7 %
Toxoplasma gondii T-complex protein 1 delta subunit T-complex protein 1 subunit beta   535 aa 521 aa 31.7 %
Toxoplasma gondii T complex chaperonin, putative T-complex protein 1 subunit beta   535 aa 516 aa 26.0 %
Leishmania infantum chaperonin containing t-complex protein, putative T-complex protein 1 subunit beta   535 aa 529 aa 31.8 %
Dictyostelium discoideum hypothetical protein T-complex protein 1 subunit beta   535 aa 604 aa 22.9 %
Giardia lamblia TCP-1 chaperonin subunit zeta T-complex protein 1 subunit beta   535 aa 516 aa 24.8 %
Theileria parva T-complex protein 1, alpha subunit , putative T-complex protein 1 subunit beta   535 aa 527 aa 34.9 %
Candida albicans similar to S. cerevisiae CCT4 (YDL143W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 546 aa 31.0 %
Cryptosporidium parvum conserved probable chaperonin containing TCP-1 delta subunit T-complex protein 1 subunit beta   535 aa 534 aa 30.7 %
Leishmania donovani T-complex protein 1, gamma subunit, putative T-complex protein 1 subunit beta   535 aa 540 aa 29.8 %
Onchocerca volvulus T-complex protein 1 subunit beta   535 aa 561 aa 27.1 %
Leishmania mexicana chaperonin containing t-complex protein, putative T-complex protein 1 subunit beta   535 aa 529 aa 31.6 %
Candida albicans similar to S. cerevisiae TCP1 (YDR212W) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 548 aa 32.8 %
Entamoeba histolytica chaperonin containing TCP-1 delta subunit, putative T-complex protein 1 subunit beta   535 aa 531 aa 30.7 %
Babesia bovis t-complex protein 1, alpha subunit, putative T-complex protein 1 subunit beta   535 aa 536 aa 34.0 %
Dictyostelium discoideum chaperonin containing TCP1 zeta subunit T-complex protein 1 subunit beta   535 aa 523 aa 26.6 %
Schistosoma japonicum ko:K09497 T-complex protein 1 subunit epsilon, putative T-complex protein 1 subunit beta   535 aa 505 aa 33.5 %
Toxoplasma gondii TCP-1 chaperonin, putative T-complex protein 1 subunit beta   535 aa 531 aa 26.9 %
Brugia malayi T-complex protein 1, zeta subunit T-complex protein 1 subunit beta   535 aa 517 aa 27.7 %
Loa Loa (eye worm) T-complex protein 1 theta subunit T-complex protein 1 subunit beta   535 aa 514 aa 26.5 %
Schistosoma mansoni chaperonin containing t-complex protein 1 theta subunit tcpq T-complex protein 1 subunit beta   535 aa 515 aa 27.2 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 146 aa 28.8 %
Babesia bovis heat shock protein 60, putative T-complex protein 1 subunit beta   535 aa 530 aa 22.3 %
Plasmodium vivax heat shock protein 60, putative T-complex protein 1 subunit beta   535 aa 540 aa 21.9 %
Plasmodium falciparum T-complex protein 1 subunit gamma T-complex protein 1 subunit beta   535 aa 522 aa 29.9 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 44.4 %
Echinococcus granulosus T complex protein 1 subunit alpha T-complex protein 1 subunit beta   535 aa 539 aa 37.1 %
Drosophila melanogaster CG8351 gene product from transcript CG8351-RA T-complex protein 1 subunit beta   535 aa 527 aa 32.3 %
Plasmodium falciparum T-complex protein 1 subunit theta T-complex protein 1 subunit beta   535 aa 516 aa 23.1 %
Neospora caninum GL18351, related T-complex protein 1 subunit beta   535 aa 530 aa 26.2 %
Trypanosoma brucei T-complex protein 1, delta subunit, putative T-complex protein 1 subunit beta   535 aa 535 aa 29.7 %
Schistosoma mansoni T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) T-complex protein 1 subunit beta   535 aa 552 aa 33.5 %
Schistosoma mansoni chaperonin containing t-complex protein 1 delta subunit tcpd T-complex protein 1 subunit beta   535 aa 530 aa 32.8 %
Candida albicans similar to S. cerevisiae CCT8 (YJL008C) subunit of chaperonin Cct ring complex involved in cytoskeleton assembly and protein fol T-complex protein 1 subunit beta   535 aa 497 aa 27.2 %
Trichomonas vaginalis chaperonin, putative T-complex protein 1 subunit beta   535 aa 561 aa 23.0 %
Leishmania infantum T-complex protein 1, gamma subunit, putative T-complex protein 1 subunit beta   535 aa 526 aa 30.0 %
Leishmania major T-complex protein 1, delta subunit, putative T-complex protein 1 subunit beta   535 aa 528 aa 28.8 %
Neospora caninum TCP-1/cpn60 family chaperonin, putative T-complex protein 1 subunit beta   535 aa 521 aa 31.7 %
Babesia bovis T-complex protein 1 epsilon subunit, putative T-complex protein 1 subunit beta   535 aa 509 aa 32.6 %
Echinococcus multilocularis T complex protein 1 subunit alpha T-complex protein 1 subunit beta   535 aa 539 aa 37.1 %
Trypanosoma cruzi T-complex protein 1, eta subunit, putative T-complex protein 1 subunit beta   535 aa 518 aa 34.9 %
Giardia lamblia TCP-1 chaperonin subunit eta T-complex protein 1 subunit beta   535 aa 543 aa 32.0 %
Trypanosoma cruzi chaperonin alpha subunit, putative T-complex protein 1 subunit beta   535 aa 535 aa 33.5 %
Theileria parva T-complex protein 1, eta subunit, putative T-complex protein 1 subunit beta   535 aa 580 aa 33.3 %
Cryptosporidium hominis t-complex protein 1, alpha subunit T-complex protein 1 subunit beta   535 aa 544 aa 33.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis hypothetical protein 0.0025 0.0066 0.0181
Plasmodium vivax unspecified product 0.0067 0.0333 0.2505
Echinococcus granulosus cathepsin l cysteine peptidase 0.0226 0.1331 0.1331
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0132 0.0737 0.1492
Brugia malayi MH1 domain containing protein 0.0016 0.0014 0.0028
Echinococcus multilocularis cysteine protease 0.0226 0.1331 0.1331
Loa Loa (eye worm) DR-78 0.0062 0.03 0.0591
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.042 0.2543 0.5232
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0041 0.0166 0.1567
Schistosoma mansoni nuclear receptor nhr-48 0.0062 0.03 0.03
Echinococcus multilocularis GPCR, family 2 0.0133 0.0744 0.0744
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0181
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.007 0.0347 0.0347
Echinococcus multilocularis jumonji domain containing protein 0.0026 0.0074 0.0074
Schistosoma mansoni nuclear hormone receptor 0.0132 0.0737 0.0737
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0225 0.1324 0.2724
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0067 0.0067
Echinococcus multilocularis hypothetical protein 0.0019 0.0029 0.0029
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0072 0.0363 0.0363
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0133 0.0744 0.0744
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0053 0.0312
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0095 0.0262
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0104 0.0565 0.534
Onchocerca volvulus 0.022 0.1289 0.2733
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0026 0.0076 0.0076
Echinococcus multilocularis tar DNA binding protein 0.0116 0.0636 0.0636
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0029 0.0119
Brugia malayi hypothetical protein 0.0062 0.03 0.0618
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0132 0.0737 0.1492
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0063 0.0307 0.0307
Echinococcus multilocularis dnaJ subfamily B 0.0344 0.2071 0.2071
Echinococcus multilocularis smad 0.0016 0.0014 0.0014
Brugia malayi MH2 domain containing protein 0.0016 0.0014 0.0028
Echinococcus multilocularis calpain 5 0.0019 0.0029 0.0029
Schistosoma mansoni lipoxygenase 0.0046 0.0202 0.0202
Brugia malayi hypothetical protein 0.047 0.2857 0.5876
Entamoeba histolytica cysteine protease, putative 0.006 0.0288 0.1992
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0062 0.03 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0442 0.1215
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.006 0.0288 0.0288
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0077 0.0396 0.2978
Trypanosoma cruzi polo-like protein kinase, putative 0.0061 0.0291 0.0599
Plasmodium vivax serine-repeat antigen (SERA) 0.006 0.0288 0.2164
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0132 0.0737 0.1492
Schistosoma mansoni jumonji domain containing protein 0.012 0.0662 0.0662
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0286 0.1702 0.7082
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0026 0.0076 0.0076
Entamoeba histolytica cysteine proteinase, putative 0.0128 0.0711 0.5238
Giardia lamblia Cathepsin B precursor 0.006 0.0288 0.1692
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.01 0.0275
Giardia lamblia Cathepsin L precursor 0.006 0.0288 0.1692
Echinococcus multilocularis expressed protein 0.0091 0.0483 0.0483
Brugia malayi cathepsin B-like cysteine proteinase 0.0789 0.4861 1
Onchocerca volvulus 0.0226 0.1331 0.2823
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.006 0.0288 0.2164
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0107
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0132 0.0737 0.1515
Schistosoma mansoni hypothetical protein 0.0133 0.0744 0.0744
Loa Loa (eye worm) helicase 0.0025 0.0066 0.0107
Schistosoma mansoni hypothetical protein 0.0133 0.0744 0.0744
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0226 0.1331 1
Onchocerca volvulus 0.0226 0.1331 0.2823
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.0333 0.0686
Echinococcus granulosus neuropeptide receptor A26 0.0457 0.2779 0.2779
Echinococcus granulosus cathepsin b 0.0789 0.4861 0.4861
Brugia malayi Papain family cysteine protease containing protein 0.0226 0.1331 0.2738
Schistosoma mansoni cpg binding protein 0.0024 0.0062 0.0062
Brugia malayi T-complex protein 1, beta subunit 0.0029 0.0094 0.0193
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0132 0.0737 0.0737
Echinococcus multilocularis chromobox protein 2 0.0025 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.006 0.0288 0.0566
Onchocerca volvulus 0.0085 0.0443 0.0918
Trichomonas vaginalis chromobox protein, putative 0.0151 0.0859 0.236
Loa Loa (eye worm) hypothetical protein 0.006 0.0288 0.0566
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0226 0.1331 0.3658
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Loa Loa (eye worm) hypothetical protein 0.0121 0.0671 0.1355
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0062 0.03 0.0591
Schistosoma mansoni thyroid hormone receptor 0.0132 0.0737 0.0737
Loa Loa (eye worm) hypothetical protein 0.0041 0.0166 0.0314
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0067 0.0111
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0132 0.0737 0.0737
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0711 0.2957
Schistosoma mansoni alpha-glucosidase 0.0327 0.1962 0.1962
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0132 0.0741 0.0741
Brugia malayi jmjC domain containing protein 0.0025 0.0067 0.0138
Mycobacterium tuberculosis Probable dehydrogenase 0.0094 0.0499 0.4719
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0108 0.0296
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0061 0.0291 0.0291
Echinococcus granulosus dnaJ subfamily B 0.0344 0.2071 0.2071
Loa Loa (eye worm) calpain 0.0019 0.0029 0.0031
Leishmania major cathepsin L-like protease 0.0226 0.1331 0.5537
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.006 0.0288 0.0792
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Echinococcus multilocularis snurportin 1 0.0302 0.1807 0.1807
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0095 0.0262
Schistosoma mansoni RAR-like nuclear receptor 0.0132 0.0737 0.0737
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0041 0.0243
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0048 0.021 0.0432
Brugia malayi cathepsin Z-like cysteine proteinase 0.006 0.0288 0.0593
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.006 0.0288 0.0566
Brugia malayi ecdysone receptor 0.0062 0.03 0.0618
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0226 0.1331 0.2718
Echinococcus multilocularis RUN 0.0017 0.0015 0.0015
Giardia lamblia Cathepsin L precursor 0.006 0.0288 0.1692
Echinococcus granulosus Chromobox protein 3 0.0025 0.0066 0.0066
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.003 0.0101 0.0957
Echinococcus granulosus phd:f box containing protein 0.0025 0.0067 0.0067
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0133 0.0744 0.153
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0522 0.3186 0.6545
Echinococcus granulosus Polycystic kidney disease protein 0.0017 0.0015 0.0015
Giardia lamblia Cathepsin B precursor 0.006 0.0288 0.1692
Echinococcus multilocularis cpg binding protein 0.0026 0.0071 0.0071
Echinococcus granulosus importin subunit beta 1 0.0028 0.0088 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.006 0.0288 0.0792
Echinococcus multilocularis chromobox protein 1 0.0151 0.0859 0.0859
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0014 0.0014
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0066 0.0135
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0067 0.0067
Schistosoma mansoni microtubule-associated protein tau 0.1608 1 1
Brugia malayi Papain family cysteine protease containing protein 0.006 0.0288 0.0593
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Schistosoma mansoni sex comb on midleg homolog 0.0042 0.0174 0.0174
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0226 0.1331 0.3658
Schistosoma mansoni steroid hormone receptor ad4bp 0.0132 0.0737 0.0737
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0091 0.0483 0.2836
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0132 0.0737 0.1515
Loa Loa (eye worm) MH2 domain-containing protein 0.0241 0.1424 0.2909
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0077 0.0396 0.0815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0132 0.0737 0.1515
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0061 0.0291 0.0572
Schistosoma mansoni cathepsin F (C01 family) 0.0226 0.1331 0.1331
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0108 0.0606
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0181
Schistosoma mansoni smad1 5 8 and 0.0016 0.0014 0.0014
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0066 0.0285
Loa Loa (eye worm) hypothetical protein 0.0085 0.0443 0.0885
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0029 0.0094 0.0094
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Schistosoma mansoni tar DNA-binding protein 0.0116 0.0636 0.0636
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0181
Echinococcus multilocularis cysteine protease 0.0226 0.1331 0.1331
Onchocerca volvulus Cathepsin L homolog 0.0226 0.1331 0.2823
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Onchocerca volvulus 0.0025 0.0066 0.0109
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0091 0.0859
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0104 0.0565 0.534
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0091 0.0482 0.1003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0067 0.0333 0.066
Trichomonas vaginalis sucrase-isomaltase, putative 0.0084 0.044 0.1208
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0181
Schistosoma mansoni retinoic acid receptor RXR 0.0132 0.0737 0.0737
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0169 0.097 0.1972
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0046 0.0202 0.0202
Schistosoma mansoni retinoid-x-receptor (RXR) 0.007 0.0347 0.0347
Brugia malayi beta-NAC-like protein 0.0029 0.0095 0.0196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0226 0.1331 0.3658
Schistosoma mansoni calpain C (C02 family) 0.0019 0.0029 0.0029
Plasmodium falciparum glutathione reductase 0.0041 0.0169 0.1267
Brugia malayi hypothetical protein 0.007 0.0347 0.0714
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Plasmodium falciparum importin beta, putative 0.0028 0.0088 0.0663
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0107
Echinococcus granulosus cpg binding protein 0.0026 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.0362
Schistosoma mansoni kinase 0.0031 0.0104 0.0104
Echinococcus granulosus Chromo domain 0.0025 0.0066 0.0066
Giardia lamblia Cathepsin B precursor 0.006 0.0288 0.1692
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0132 0.0737 0.0737
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0132 0.0737 0.0737
Onchocerca volvulus Protein ultraspiracle homolog 0.0132 0.0737 0.1548
Plasmodium falciparum serine repeat antigen 8 0.006 0.0288 0.2164
Schistosoma mansoni rab6-interacting 0.0017 0.0015 0.0015
Echinococcus granulosus histone lysine methyltransferase setb 0.0075 0.0383 0.0383
Loa Loa (eye worm) TAR-binding protein 0.0116 0.0636 0.1284
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0067 0.0111
Leishmania major kinesin, putative 0.0019 0.0029 0.0119
Brugia malayi nuclear receptor NHR-67 0.0062 0.03 0.0618
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0062 0.03 0.0618
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0041 0.0057
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0077 0.0396 0.0815
Schistosoma mansoni myelin transcription factor 1 myt1 0.0048 0.021 0.021
Schistosoma mansoni hypothetical protein 0.0025 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.006 0.0288 0.2164
Echinococcus multilocularis cathepsin L cysteine protease 0.0226 0.1331 0.1331
Echinococcus multilocularis Smad4 0.0016 0.0014 0.0014
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0031 0.0108 0.0199
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0066 0.0494
Brugia malayi CHD4 protein 0.0026 0.0074 0.0153
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Brugia malayi hypothetical protein 0.076 0.4678 0.9623
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.03 0.0612
Brugia malayi cathepsin L precursor 0.006 0.0288 0.0593
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0053 0.0109
Entamoeba histolytica cysteine protease, putative 0.006 0.0288 0.1992
Plasmodium falciparum serine repeat antigen 9 0.006 0.0288 0.2164
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0169 0.097 0.097
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0041 0.0166 0.1567
Plasmodium vivax JmjC domain containing protein 0.0025 0.0067 0.0506
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Loa Loa (eye worm) hypothetical protein 0.007 0.0347 0.0688
Loa Loa (eye worm) hypothetical protein 0.0133 0.0744 0.1506
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0225 0.1324 0.1324
Entamoeba histolytica hypothetical protein 0.0029 0.0095 0.0512
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.006 0.0288 0.0792
Echinococcus multilocularis cathepsin L 0.0128 0.0711 0.0711
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0026 0.0074 0.0074
Onchocerca volvulus Bile acid receptor homolog 0.0132 0.0737 0.1548
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0333 0.0686
Loa Loa (eye worm) hypothetical protein 0.0066 0.0327 0.0647
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.006 0.0288 0.0792
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0084 0.0231
Plasmodium falciparum serine repeat antigen 2 0.006 0.0288 0.2164
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0061 0.0291 0.0291
Loa Loa (eye worm) glutathione reductase 0.0041 0.0169 0.032
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0014 0.0014
Brugia malayi serine/threonine-protein kinase plk-2 0.0061 0.0291 0.0599
Leishmania major cathepsin L-like protease 0.0226 0.1331 0.5537
Schistosoma mansoni tar DNA-binding protein 0.0116 0.0636 0.0636
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0154
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.044 0.3155
Loa Loa (eye worm) hypothetical protein 0.007 0.0347 0.0688
Mycobacterium ulcerans acyl-CoA synthetase 0.0041 0.0166 0.1567
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0077 0.0396 0.2328
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Echinococcus granulosus cathepsin L cysteine protease 0.0128 0.0711 0.0711
Plasmodium falciparum cysteine proteinase falcipain 3 0.0226 0.1331 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0062 0.03 0.0591
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0066 0.0328 0.0328
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0183 0.1058 0.1058
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0041 0.0166 0.1567
Onchocerca volvulus 0.0041 0.0166 0.0324
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0067 0.0333 0.0686
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0226 0.1331 0.1331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Giardia lamblia Encystation-specific protease 0.006 0.0288 0.1692
Loa Loa (eye worm) hypothetical protein 0.0067 0.0333 0.066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.006 0.0288 0.0792
Onchocerca volvulus 0.0066 0.0327 0.067
Brugia malayi mbt repeat family protein 0.0042 0.0174 0.0357
Brugia malayi cahepsin L-like non-peptiedase homolog 0.006 0.0288 0.0593
Trypanosoma cruzi major cysteine proteinase, putative 0.006 0.0288 0.0593
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0066 0.0066
Onchocerca volvulus 0.0226 0.1331 0.2823
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.01 0.0275
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0026 0.0074 0.0074
Toxoplasma gondii preprocathepsin c precursor, putative 0.006 0.0288 0.1692
Loa Loa (eye worm) hypothetical protein 0.0077 0.0396 0.0789
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0053 0.0502
Giardia lamblia Cathepsin L-like protease 0.006 0.0288 0.1692
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0133 0.0744 0.0744
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.006 0.0288 0.0288
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0029 0.0029
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0169 0.097 0.4035
Brugia malayi calpain 5 0.0019 0.0029 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0029 0.0094 0.0391
Schistosoma mansoni hypothetical protein 0.0933 0.5763 0.5763
Toxoplasma gondii t-complex protein beta subunit 0.0029 0.0094 0.0552
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0029 0.0094 0.0706
Loa Loa (eye worm) hypothetical protein 0.0042 0.0174 0.033
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0084 0.044 0.2582
Mycobacterium ulcerans acyl-CoA synthetase 0.0041 0.0166 0.1567
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.01 0.0275
Leishmania major GTP-binding protein, putative 0.0021 0.0041 0.0172
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0132 0.0737 0.0737
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0094 0.0499 0.4719
Brugia malayi Cathepsin L-like precursor 0.0226 0.1331 0.2738
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0053 0.0146
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.01 0.0275
Schistosoma mansoni importin beta-1 0.0028 0.0088 0.0088
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0067 0.0067
Onchocerca volvulus 0.0226 0.1331 0.2823
Brugia malayi nuclear hormone receptor 0.0062 0.03 0.0618
Echinococcus multilocularis lysosomal alpha glucosidase 0.038 0.2294 0.2294
Onchocerca volvulus 0.0159 0.0908 0.1916
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0066 0.0494
Echinococcus multilocularis neuropeptide receptor A26 0.0457 0.2779 0.2779
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0066 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0132 0.0737 0.1492
Brugia malayi tailless protein 0.0062 0.03 0.0618
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.044 0.1208
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0789 0.4861 0.4861
Brugia malayi chromobox protein homolog 3 0.0085 0.0442 0.0909
Schistosoma mansoni calpain (C02 family) 0.0019 0.0029 0.0029
Giardia lamblia Cathepsin B precursor 0.0286 0.1702 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0225 0.1324 0.1324
Leishmania major cathepsin L-like protease 0.0226 0.1331 0.5537
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.038 0.2294 0.4705
Loa Loa (eye worm) hypothetical protein 0.0159 0.0908 0.1845
Schistosoma mansoni nuclear receptor 0.0062 0.03 0.03
Schistosoma mansoni lamin 0.0017 0.002 0.002
Brugia malayi AMP-binding enzyme family protein 0.0041 0.0166 0.0341
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0028 0.0165
Giardia lamblia Cathepsin L precursor 0.006 0.0288 0.1692
Giardia lamblia Cathepsin B precursor 0.0286 0.1702 1
Echinococcus multilocularis musashi 0.0017 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0302 0.1807 0.1807
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0128 0.0711 0.0711
Entamoeba histolytica papain family cysteine protease domain containing protein 0.006 0.0288 0.1992
Echinococcus multilocularis ecdysone induced protein 78C 0.0132 0.0737 0.0737
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0132 0.0737 0.1515
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0288 0.0792
Brugia malayi conserved hypotetical protein 0.0062 0.03 0.0618
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Plasmodium vivax glutathione reductase, putative 0.0041 0.0169 0.1267
Plasmodium vivax serine-repeat antigen (SERA), putative 0.006 0.0288 0.2164
Giardia lamblia Dipeptidyl-peptidase I precursor 0.006 0.0288 0.1692
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0132 0.0737 0.0737
Loa Loa (eye worm) hypothetical protein 0.0159 0.0908 0.1845
Entamoeba histolytica hypothetical protein 0.0025 0.0066 0.0285
Echinococcus granulosus endonuclease exonuclease phosphatase 0.017 0.0975 0.0975
Schistosoma mansoni alpha glucosidase 0.0084 0.044 0.044
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0286 0.1702 0.1702
Entamoeba histolytica hypothetical protein 0.0032 0.0109 0.0616
Giardia lamblia Hypothetical protein 0.006 0.0288 0.1692
Onchocerca volvulus 0.0062 0.03 0.0612
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0053 0.0109
Onchocerca volvulus 0.0226 0.1331 0.2823
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0291 0.08
Trypanosoma cruzi polo-like protein kinase, putative 0.0061 0.0291 0.0599
Entamoeba histolytica cysteine proteinase 1, putative 0.0128 0.0711 0.5238
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0053 0.0221
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0067 0.0067
Schistosoma mansoni hypothetical protein 0.0077 0.0396 0.0396
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0041 0.031
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0077 0.0396 0.0396
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0053 0.0187
Brugia malayi Cathepsin L-like precursor 0.0226 0.1331 0.2738
Loa Loa (eye worm) latrophilin receptor protein 2 0.0133 0.0744 0.1506
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0132 0.0737 0.1515
Trichomonas vaginalis set domain proteins, putative 0.0594 0.3638 1
Schistosoma mansoni nuclear hormone receptor 0.0062 0.03 0.03
Mycobacterium ulcerans acyl-CoA synthetase 0.0041 0.0166 0.1567
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0066 0.0181
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0225 0.1324 0.1324
Plasmodium vivax unspecified product 0.006 0.0288 0.2164
Echinococcus multilocularis PHD finger protein rhinoceros 0.0019 0.0028 0.0028
Echinococcus multilocularis Chromo domain 0.0025 0.0066 0.0066
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.006 0.0288 0.2164
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0226 0.1331 0.3658
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0041 0.0172
Loa Loa (eye worm) hypothetical protein 0.0132 0.0737 0.1492
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0029 0.0029
Onchocerca volvulus 0.0062 0.03 0.0612
Brugia malayi Glycosyl hydrolases family 31 protein 0.038 0.2294 0.472
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0328 0.0328
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0055 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0181
Loa Loa (eye worm) intermediate filament protein 0.0017 0.002 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0181
Plasmodium falciparum phd finger protein, putative 0.0019 0.0028 0.0211
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0041 0.0085
Brugia malayi Protein cec-1. 0.0025 0.0066 0.0135
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0091 0.0483 0.3627
Brugia malayi cathepsin L-like precursor 0.0159 0.0908 0.1868
Onchocerca volvulus 0.0044 0.0189 0.0374
Brugia malayi Smad1 0.0016 0.0014 0.0028
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0183 0.1058 0.1058
Loa Loa (eye worm) steroid hormone receptor 0.0132 0.0737 0.1492
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0028 0.0165
Entamoeba histolytica hypothetical protein 0.0023 0.0055 0.0199
Brugia malayi hypothetical protein 0.007 0.0349 0.0718
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0132 0.0737 0.0737
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.1058 0.1058
Loa Loa (eye worm) hypothetical protein 0.047 0.2857 0.5865
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0111
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0091 0.0859
Giardia lamblia Cysteine protease 0.006 0.0288 0.1692
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0066 0.0181
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0029 0.0059
Echinococcus granulosus nuclear receptor nhr 48 0.0062 0.03 0.03
Toxoplasma gondii exonuclease III APE 0.0023 0.0053 0.0312
Brugia malayi jmjC domain containing protein 0.0132 0.0741 0.1524
Trypanosoma cruzi cysteine peptidase, putative 0.0226 0.1331 0.2738
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0133 0.0744 0.0744
Plasmodium falciparum T-complex protein 1 subunit beta 0.0029 0.0094 0.0706
Schistosoma mansoni tar DNA-binding protein 0.0116 0.0636 0.0636
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0009
Loa Loa (eye worm) heterochromatin protein 1 0.0151 0.0859 0.1743
Loa Loa (eye worm) hypothetical protein 0.0041 0.0166 0.0314
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0107
Echinococcus granulosus ecdysone induced protein 78C 0.0132 0.0737 0.0737
Loa Loa (eye worm) hypothetical protein 0.0159 0.0908 0.1845
Schistosoma mansoni lamin 0.0017 0.002 0.002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0029 0.0059
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0041 0.0041
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0053 1
Schistosoma mansoni sex comb on midleg homolog 0.0042 0.0174 0.0174
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0066 0.0181
Leishmania major cathepsin L-like protease 0.0397 0.2404 1
Brugia malayi Papain family cysteine protease containing protein 0.006 0.0288 0.0593
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0226 0.1331 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0159 0.0908 0.1868
Brugia malayi PHD-finger family protein 0.0019 0.0028 0.0058
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0067 0.0067
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0067 0.028
Trypanosoma brucei glucosidase, putative 0.0084 0.044 0.1828
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0066 0.0066
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0041 0.0243
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.006 0.0288 0.2164
Giardia lamblia Cathepsin B precursor 0.0286 0.1702 1
Trypanosoma cruzi cruzipain precursor, putative 0.0397 0.2404 0.4945
Trypanosoma cruzi cysteine proteinase, putative 0.0128 0.0711 0.1462
Entamoeba histolytica cysteine proteinase, putative 0.0159 0.0908 0.6753
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0014 0.0014
Giardia lamblia TCP-1 chaperonin subunit beta 0.0029 0.0094 0.0552
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0088 0.0088
Leishmania major T-complex protein 1, beta subunit, putative 0.0029 0.0094 0.0391
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.01 0.0275
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0029 0.0059
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.1058 0.1058
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0287 0.0788
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0082 0.0224
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.01 0.0275
Plasmodium falciparum serine repeat antigen 1 0.006 0.0288 0.2164
Trypanosoma brucei cysteine peptidase C (CPC) 0.0286 0.1702 0.7082
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0286 0.1702 0.4679
Echinococcus multilocularis transcription factor btf3 0.0029 0.0095 0.0095
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0094 0.0499 0.4719
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0029 0.0059
Loa Loa (eye worm) hypothetical protein 0.0063 0.0307 0.0606
Loa Loa (eye worm) cysteine protease 0.0226 0.1331 0.2718
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0442 0.0916
Giardia lamblia PHD finger protein 15 0.0019 0.0028 0.0165
Schistosoma mansoni cathepsin s 0.0067 0.0333 0.0333
Echinococcus granulosus lysine specific demethylase 5A 0.0095 0.0507 0.0507
Mycobacterium tuberculosis Probable oxidoreductase 0.0104 0.0565 0.534
Trichomonas vaginalis chromobox protein, putative 0.0091 0.0482 0.1326
Echinococcus multilocularis histone acetyltransferase MYST2 0.0048 0.021 0.021
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0094 0.0499 0.8354
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0132 0.0737 0.0737
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0091 0.0483 0.0483
Loa Loa (eye worm) calpain 5 0.0019 0.0029 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0288 0.0792
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0029 0.0094 0.0258
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0108 0.0296
Schistosoma mansoni chromobox protein 0.0025 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.0362
Giardia lamblia Cathepsin L-like protease 0.006 0.0288 0.1692
Brugia malayi fibroinase precursor 0.006 0.0288 0.0593
Schistosoma mansoni jumonji/arid domain-containing protein 0.0095 0.0507 0.0507
Brugia malayi hypothetical protein 0.0017 0.0015 0.003
Loa Loa (eye worm) cathepsin B 0.0286 0.1702 0.3484
Trichomonas vaginalis chaperonin, putative 0.0029 0.0094 0.0258
Echinococcus multilocularis nuclear receptor nhr 48 0.0062 0.03 0.03
Loa Loa (eye worm) mbt repeat family protein 0.0042 0.0174 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0159 0.0908 0.2496
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0066 0.0494
Schistosoma mansoni cellular tumor antigen P53 0.0085 0.0443 0.0443
Brugia malayi AMP-binding enzyme family protein 0.0041 0.0166 0.0341
Brugia malayi Glycosyl hydrolases family 31 protein 0.0031 0.0108 0.0221
Entamoeba histolytica cysteine proteinase, putative 0.0226 0.1331 1
Schistosoma mansoni ran 0.0021 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0111
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0107
Brugia malayi hypothetical protein 0.0017 0.0015 0.003
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0067 0.0067
Schistosoma mansoni Mername-AA248 (C02 family) 0.0019 0.0029 0.0029
Loa Loa (eye worm) jmjC domain-containing protein 0.0095 0.0507 0.1018
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0183 0.1058 0.44
Trypanosoma cruzi kinesin, putative 0.0019 0.0029 0.0059
Plasmodium vivax multidomain scavenger receptor, putative 0.0017 0.0015 0.0111
Echinococcus granulosus cathepsin b 0.0789 0.4861 0.4861
Toxoplasma gondii cathepsin B 0.0286 0.1702 1
Toxoplasma gondii thioredoxin reductase 0.0041 0.0169 0.099
Brugia malayi Cathepsin L-like precursor 0.0159 0.0908 0.1868
Leishmania major alpha glucosidase II subunit, putative 0.0084 0.044 0.1828
Loa Loa (eye worm) hypothetical protein 0.0085 0.0442 0.0883
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.1807 0.3699
Brugia malayi Cathepsin L-like precursor 0.0226 0.1331 0.2738
Schistosoma mansoni jumonji/arid domain-containing protein 0.0095 0.0507 0.0507
Plasmodium vivax unspecified product 0.0128 0.0711 0.5341
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0226 0.1331 0.3658
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0169 0.097 0.097
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0029 0.0119
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.03 0.03
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0169 0.097 0.7226
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0067 0.0067
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0029 0.0094 0.0193
Loa Loa (eye worm) calpain family protein 1 0.0063 0.0307 0.0606
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0055 0.015
Brugia malayi steroid hormone receptor 0.0132 0.0737 0.1515
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0062 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0107
Schistosoma mansoni nuclear receptor 0.0062 0.03 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0181
Entamoeba histolytica cysteine proteinase, putative 0.0128 0.0711 0.5238
Echinococcus granulosus expressed protein 0.0091 0.0483 0.0483
Brugia malayi Cathepsin L-like precursor 0.0226 0.1331 0.2738
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0042 0.0174 0.034
Plasmodium vivax serine-repeat antigen (SERA), putative 0.006 0.0288 0.2164
Entamoeba histolytica cysteine protease, putative 0.006 0.0288 0.1992
Trypanosoma cruzi transcription factor btf3, putative 0.0029 0.0095 0.0196
Leishmania major cathepsin L-like protease 0.0397 0.2404 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0132 0.0737 0.1515
Brugia malayi hypothetical protein 0.007 0.0347 0.0714
Entamoeba histolytica hypothetical protein 0.0025 0.0066 0.0285
Schistosoma mansoni cathepsin C 0.006 0.0288 0.0288
Brugia malayi Cathepsin L-like precursor 0.0067 0.0333 0.0686
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0019 0.0028 0.0028
Loa Loa (eye worm) transcription factor SMAD2 0.0241 0.1424 0.2909
Onchocerca volvulus 0.047 0.2857 0.6094
Trichomonas vaginalis maltase-glucoamylase, putative 0.0031 0.0108 0.0296
Echinococcus granulosus snurportin 1 0.0302 0.1807 0.1807
Echinococcus granulosus thioredoxin glutathione reductase 0.0042 0.0172 0.0172
Brugia malayi Importin beta-1 subunit 0.0028 0.0088 0.0181
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0108 0.0221
Echinococcus granulosus cathepsin L 0.006 0.0288 0.0288
Trypanosoma brucei transcription factor BTF3, putative 0.0029 0.0095 0.0396
Trichomonas vaginalis chromobox protein, putative 0.0091 0.0482 0.1326
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0075 0.0383 0.0383
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0053 0.0081
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.0347 0.0714
Loa Loa (eye worm) MBCTL1 0.0048 0.021 0.0405
Brugia malayi Pre-SET motif family protein 0.0522 0.3186 0.6555
Brugia malayi hypothetical protein 0.0025 0.0066 0.0135
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0091 0.0483 0.0968
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0055 0.015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0132 0.0737 0.1515
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0032 0.0109 0.0616
Echinococcus granulosus transcription factor btf3 0.0029 0.0095 0.0095
Trypanosoma cruzi transcription factor btf3, putative 0.0029 0.0095 0.0196
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0067 0.0067
Onchocerca volvulus 0.0226 0.1331 0.2823
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0067 0.0067
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0075 0.0383 0.0383
Brugia malayi calpain family protein 1 0.0063 0.0307 0.0632
Entamoeba histolytica hypothetical protein 0.0032 0.0109 0.0616
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0084 0.044 0.0878
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0132 0.0737 0.1515
Onchocerca volvulus 0.0226 0.1331 0.2823
Trypanosoma brucei glycosyl hydrolase-like protein 0.0031 0.0108 0.0448
Echinococcus granulosus thyroid hormone receptor alpha 0.0062 0.03 0.03
Brugia malayi Calcitonin receptor-like protein seb-1 0.042 0.2543 0.5232
Trypanosoma brucei polo-like protein kinase 0.0061 0.0291 0.1211
Schistosoma mansoni coup transcription factor 0.0132 0.0737 0.0737
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.007 0.0347 0.0688
Schistosoma mansoni transcription factor LCR-F1 0.0032 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0789 0.4861 1
Echinococcus granulosus chromobox protein 1 0.0151 0.0859 0.0859
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0226 0.1331 0.3658
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0181
Echinococcus granulosus tumor protein p63 0.058 0.3548 0.3548
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0077 0.0396 0.2978
Schistosoma mansoni ap endonuclease 0.0023 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0226 0.1331 0.3658
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0132 0.0737 0.1515
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0029 0.0094 0.0094
Trypanosoma cruzi cysteine protease, putative 0.0128 0.0711 0.1462
Echinococcus multilocularis lipoxygenase domain containing protein 0.0017 0.0015 0.0015
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0017 0.002 0.0013
Brugia malayi Papain family cysteine protease containing protein 0.0128 0.0711 0.1462
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0288 0.0792
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0054 0.025 0.025
Brugia malayi Nuclear hormone receptor-like 1 0.0132 0.0737 0.1515
Echinococcus granulosus calpain A 0.0066 0.0328 0.0328
Onchocerca volvulus Alhambra homolog 0.0019 0.0028 0.0029
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0132 0.0737 0.0737
Entamoeba histolytica serine/threonine protein kinase, putative 0.0061 0.0291 0.2015
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0066 0.0285
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0029 0.0059
Echinococcus granulosus PHD finger protein rhinoceros 0.0019 0.0028 0.0028
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0041 0.0166 0.1567
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0183 0.1058 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0041 0.0166 0.1053
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0029 0.0094 0.0094
Onchocerca volvulus 0.076 0.4678 1
Loa Loa (eye worm) hypothetical protein 0.0132 0.0737 0.1492
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0066 0.0066
Entamoeba histolytica hypothetical protein 0.0025 0.0066 0.0285
Echinococcus granulosus lipoxygenase domain containing protein 0.0017 0.0015 0.0015
Plasmodium vivax vivapain-2 0.0226 0.1331 1
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0029 0.0094 0.0094
Toxoplasma gondii cathepsin CPL 0.0226 0.1331 0.7819
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0067 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0132 0.0737 0.0737
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0014 0.0014
Brugia malayi Heterochromatin protein 1 0.0151 0.0859 0.1766
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.044 0.1208
Brugia malayi ecdysteroid receptor 0.0132 0.0737 0.1515
Loa Loa (eye worm) RNA binding protein 0.0116 0.0636 0.1284
Brugia malayi Steroid receptor seven-up type 2 0.0132 0.0737 0.1515
Plasmodium vivax acyl-CoA synthetase, putative 0.003 0.0101 0.0761
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0041 0.031
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0053 0.0221
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.006 0.0288 0.2164
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0091 0.0483 0.0993
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0048 0.021 0.021
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0132 0.0737 0.1515
Loa Loa (eye worm) hypothetical protein 0.006 0.0288 0.0566
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0088 0.0367
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0066 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.0538 0.0538
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0075 0.0383 0.0383
Loa Loa (eye worm) fibroinase 0.0226 0.1331 0.2718
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0041 0.0166 0.1567
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Echinococcus multilocularis geminin 0.0933 0.5763 0.5763
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0128 0.0711 0.0711
Giardia lamblia Dipeptidyl-peptidase I precursor 0.006 0.0288 0.1692
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.006 0.0288 0.2164
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0094 0.0499 0.4719
Plasmodium vivax serine-repeat antigen (SERA) 0.006 0.0288 0.2164
Entamoeba histolytica cysteine protease, putative 0.006 0.0288 0.1992
Loa Loa (eye worm) hypothetical protein 0.0132 0.0737 0.1492
Entamoeba histolytica cysteine protease, putative 0.0226 0.1331 1
Leishmania major basic transcription factor 3a, putative 0.0029 0.0095 0.0396
Schistosoma mansoni hypothetical protein 0.0344 0.2071 0.2071
Brugia malayi jmjC domain containing protein 0.0095 0.0507 0.1043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0226 0.1331 0.3658
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0108 0.0296
Echinococcus granulosus GPCR family 2 0.0133 0.0744 0.0744
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0789 0.4861 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.006 0.0288 0.2164
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0067 0.0395
Echinococcus multilocularis polycomb protein SCMH1 0.0042 0.0174 0.0174
Entamoeba histolytica acyl-CoA synthetase, putative 0.0041 0.0166 0.1053
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0066 0.0494
Echinococcus multilocularis FTZ F1 alpha 0.0132 0.0737 0.0737
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.006 0.0288 0.0288
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0046 0.0202 0.0202
Toxoplasma gondii aldehyde dehydrogenase 0.0183 0.1058 0.6213
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0169 0.097 0.4035
Entamoeba histolytica cysteine proteinase 2 0.0128 0.0711 0.5238
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.1324 0.1324
Brugia malayi Latrophilin receptor protein 2 0.0133 0.0744 0.153
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.006 0.0288 0.2164
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0291 0.08
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0132 0.0737 0.0737
Brugia malayi M-phase phosphoprotein, mpp8 0.0025 0.0066 0.0135
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0002
Brugia malayi Nuclear hormone receptor E75 0.0062 0.03 0.0618
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0077 0.0396 0.0815
Schistosoma mansoni hypothetical protein 0.0019 0.0028 0.0028
Toxoplasma gondii cathepsin CPC1 0.006 0.0288 0.1692
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0067 0.0395
Echinococcus granulosus calpain 5 0.0019 0.0029 0.0029
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0116 0.0636 0.1284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0288 0.0792
Schistosoma mansoni ap endonuclease 0.0023 0.0053 0.0053
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0053 0.0502
Trichomonas vaginalis chromobox protein, putative 0.0151 0.0859 0.236
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0107
Trypanosoma cruzi kinesin, putative 0.0019 0.0029 0.0059
Brugia malayi nuclear receptor RXR 0.0062 0.03 0.0618
Loa Loa (eye worm) hypothetical protein 0.007 0.0347 0.0688
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0226 0.1331 0.3658
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.01 0.0275
Brugia malayi Cathepsin L-like precursor 0.0226 0.1331 0.2738
Echinococcus granulosus polycomb protein SCMH1 0.0042 0.0174 0.0174
Schistosoma mansoni cathepsin S (C01 family) 0.006 0.0288 0.0288
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0169 0.097 0.1995
Loa Loa (eye worm) hypothetical protein 0.042 0.2543 0.5218
Plasmodium falciparum acyl-CoA synthetase 0.003 0.0101 0.0761
Loa Loa (eye worm) CXXC zinc finger family protein 0.0024 0.0062 0.01
Mycobacterium ulcerans fatty-acid-CoA ligase 0.003 0.0101 0.0957
Giardia lamblia Cathepsin L precursor 0.006 0.0288 0.1692
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.006 0.0288 0.2164
Loa Loa (eye worm) hypothetical protein 0.076 0.4678 0.9622
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0288 0.0792
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0181
Brugia malayi MH1 domain containing protein 0.0016 0.0014 0.0028
Plasmodium vivax basic transcription factor 3b, putative 0.0029 0.0095 0.0716
Echinococcus granulosus chromobox protein 2 0.0025 0.0066 0.0066
Echinococcus granulosus calpain 7 C02 family 0.0019 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0067 0.0333 0.066
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.03 0.03
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0132 0.0737 0.1515
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0287 0.0788
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.044 0.3155
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0225 0.1324 0.2704
Toxoplasma gondii cathepsin CPC2 0.006 0.0288 0.1692
Schistosoma mansoni ran 0.0021 0.0041 0.0041
Brugia malayi nuclear hormone receptor family member nhr-6 0.0062 0.03 0.0618
Loa Loa (eye worm) hypothetical protein 0.0132 0.0737 0.1492
Echinococcus multilocularis microtubule associated protein 2 0.1608 1 1
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0091 0.0859
Echinococcus granulosus peregrin 0.0019 0.0028 0.0028
Giardia lamblia Cysteine protease 0.006 0.0288 0.1692
Loa Loa (eye worm) hypothetical protein 0.0067 0.0333 0.066
Schistosoma mansoni cpg binding protein 0.0026 0.0071 0.0071
Onchocerca volvulus 0.0017 0.0015 0.0000055409
Loa Loa (eye worm) hypothetical protein 0.0226 0.1331 0.2718
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0789 0.4861 0.4861
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0066 0.0386
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0132 0.0737 0.0737
Schistosoma mansoni intermediate filament proteins 0.0017 0.002 0.002
Echinococcus multilocularis SAM and MBT domain containing protein 0.0042 0.0174 0.0174
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.006 0.0288 0.0288
Entamoeba histolytica transcription factor BTF3, putative 0.0029 0.0095 0.0512
Onchocerca volvulus 0.0594 0.3638 0.777
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0128 0.0711 0.0711
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0066 0.0181
Echinococcus granulosus chromobox protein 1 0.0151 0.0859 0.0859
Echinococcus multilocularis calpain family protein 1, d 0.0044 0.0189 0.0189
Loa Loa (eye worm) runx1 0.0095 0.0509 0.1021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Echinococcus granulosus transcription factor Dp 1 0.0098 0.0524 0.0524
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0062 0.03 0.03
Brugia malayi RNA recognition motif domain containing protein 0.0116 0.0636 0.1309
Plasmodium falciparum serine repeat antigen 4 0.006 0.0288 0.2164
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0029 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0291 0.08
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.006 0.0288 0.0792
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.033 0.1981 0.4075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0225 0.1324 0.1324
Schistosoma mansoni polycystin 1-related 0.0017 0.0015 0.0015
Echinococcus multilocularis Polycystic kidney disease protein 0.0017 0.0015 0.0015
Plasmodium vivax vivapain-3 0.0128 0.0711 0.5341
Leishmania major 4-coumarate:coa ligase-like protein 0.0041 0.0166 0.069
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.1058 1
Echinococcus granulosus jumonji domain containing protein 0.0026 0.0074 0.0074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.03 0.03
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0075 0.0383 0.0383
Trypanosoma cruzi cysteine peptidase, putative 0.0128 0.0711 0.1462
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0405
Schistosoma mansoni hypothetical protein 0.0133 0.0744 0.0744
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0066 0.0181
Schistosoma mansoni cathepsin F (C01 family) 0.0226 0.1331 0.1331
Schistosoma mansoni smad1 5 8 and 0.0016 0.0014 0.0014
Onchocerca volvulus 0.006 0.0288 0.0586
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0088 0.0518
Entamoeba histolytica cysteine protease, putative 0.006 0.0288 0.1992
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0028 0.0211
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0061 0.0291 0.1211
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0108 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0132 0.0737 0.1515
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0091 0.0483 0.3627
Loa Loa (eye worm) hypothetical protein 0.0132 0.0737 0.1492
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0053 0.0109
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0132 0.0737 0.0737
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0153 0.0288
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.007 0.0347 0.0688
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0288 0.0792
Echinococcus multilocularis lamin dm0 0.0017 0.002 0.002
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.0169 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0442 0.1215
Brugia malayi mbt repeat family protein 0.0042 0.0174 0.0357
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0032 0.0109 0.0109
Brugia malayi Cathepsin L-like precursor 0.0159 0.0908 0.1868
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0132 0.0737 0.1515
Brugia malayi cathepsin L-like cysteine proteinase 0.006 0.0288 0.0593
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.006 0.0288 0.0288
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0108 0.0221
Echinococcus multilocularis neuropeptide s receptor 0.0457 0.2779 0.2779
Brugia malayi calpain 7 0.0019 0.0029 0.0059
Echinococcus granulosus SAM and MBT domain containing protein 0.0042 0.0174 0.0174
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0066 0.0135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0711 0.1954
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.044 0.0904
Brugia malayi Intermediate filament tail domain containing protein 0.0017 0.002 0.0042
Entamoeba histolytica hypothetical protein 0.006 0.0288 0.1992
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.044 0.1208
Brugia malayi intermediate filament protein 0.0017 0.002 0.0042
Entamoeba histolytica cysteine protease, putative 0.0128 0.0711 0.5238
Entamoeba histolytica cysteine proteinase, putative 0.0128 0.0711 0.5238
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0291 0.0291
Schistosoma mansoni loxhd1 0.0017 0.0015 0.0015
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.006 0.0288 0.2164
Giardia lamblia Dipeptidyl-peptidase I precursor 0.006 0.0288 0.1692
Trypanosoma cruzi cysteine proteinase, putative 0.0128 0.0711 0.1462
Onchocerca volvulus Cathepsin L homolog 0.0226 0.1331 0.2823
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0181
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0108 0.0296
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0169 0.097 0.1995
Echinococcus granulosus cathepsin L 0.0128 0.0711 0.0711
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0132 0.0737 0.0737
Plasmodium falciparum serine repeat antigen 5 0.006 0.0288 0.2164
Loa Loa (eye worm) hypothetical protein 0.006 0.0288 0.0566
Loa Loa (eye worm) hypothetical protein 0.006 0.0288 0.0566
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0041 0.0169 0.1594
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0029 0.0119
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.03 0.03
Echinococcus granulosus calpain A 0.0019 0.0029 0.0029
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0029 0.0059
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0048 0.021 0.021
Brugia malayi cathepsin Z-like cysteine proteinase 0.006 0.0288 0.0593
Schistosoma mansoni tar DNA-binding protein 0.0116 0.0636 0.0636
Plasmodium falciparum serine repeat antigen 3 0.006 0.0288 0.2164
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0032 0.0109 0.0109
Brugia malayi nuclear receptor NHR-88 0.0132 0.0737 0.1515
Loa Loa (eye worm) hypothetical protein 0.0132 0.0737 0.1492
Schistosoma mansoni Smad4 0.0016 0.0014 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0711 0.2957
Toxoplasma gondii TIM10 family protein, putative 0.0091 0.0483 0.2836
Plasmodium falciparum serine repeat antigen 6 0.006 0.0288 0.2164
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0181
Entamoeba histolytica cysteine protease, putative 0.006 0.0288 0.1992
Plasmodium vivax calpain, putative 0.0019 0.0029 0.0215
Loa Loa (eye worm) hypothetical protein 0.0075 0.0383 0.0762
Echinococcus granulosus Smad4 0.0016 0.0014 0.0014
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0053 1
Brugia malayi Doublecortin family protein 0.0017 0.0015 0.003
Echinococcus multilocularis calpain A 0.0066 0.0328 0.0328
Onchocerca volvulus 0.0132 0.0737 0.1548
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0132 0.0737 0.0737
Brugia malayi Nuclear hormone receptor E75 0.0062 0.03 0.0618
Echinococcus multilocularis cathepsin L 0.006 0.0288 0.0288
Plasmodium vivax vivapain-2 0.0226 0.1331 1
Loa Loa (eye worm) hypothetical protein 0.0132 0.0737 0.1492
Leishmania major hypothetical protein, conserved 0.0025 0.0067 0.028
Brugia malayi Pre-SET motif family protein 0.0075 0.0383 0.0788
Loa Loa (eye worm) hypothetical protein 0.0121 0.0671 0.1355
Plasmodium vivax thioredoxin reductase, putative 0.0041 0.0169 0.1267
Schistosoma mansoni hypothetical protein 0.0032 0.0109 0.0109
Brugia malayi hypothetical protein 0.0121 0.0671 0.1379
Brugia malayi F/Y-rich N-terminus family protein 0.0016 0.0013 0.0026
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0132 0.0737 0.1492
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.006 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Entamoeba histolytica protein kinase, putative 0.0019 0.003 0.001
Echinococcus multilocularis neutral alpha glucosidase AB 0.0084 0.044 0.044
Leishmania major cathepsin L-like protease 0.0226 0.1331 0.5537
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0526 0.3207 0.3207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Echinococcus granulosus smad 0.0016 0.0014 0.0014
Echinococcus granulosus lamin 0.0017 0.002 0.002
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0029 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0291 0.08
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0019 0.0029 0.0059
Giardia lamblia Cathepsin L precursor 0.006 0.0288 0.1692
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.01 0.0275
Onchocerca volvulus 0.0025 0.0066 0.0109
Brugia malayi Bromodomain containing protein 0.0019 0.0028 0.0058
Entamoeba histolytica hypothetical protein 0.0032 0.0109 0.0616
Brugia malayi orphan nuclear receptor NR2E1 0.0062 0.03 0.0618
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0029 0.0094 0.0501
Loa Loa (eye worm) hypothetical protein 0.0041 0.0166 0.0314
Echinococcus multilocularis cathepsin b 0.0789 0.4861 0.4861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Echinococcus multilocularis transcription factor Dp 1 0.0098 0.0524 0.0524
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.044 0.1208
Schistosoma mansoni thyroid hormone receptor 0.0132 0.0737 0.0737
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0066 0.0328 0.0328
Echinococcus granulosus RUN 0.0017 0.0015 0.0015
Brugia malayi Cathepsin L-like precursor 0.0226 0.1331 0.2738
Plasmodium falciparum LCCL domain-containing protein 0.0017 0.0015 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0108 0.0296
Trypanosoma cruzi major cysteine proteinase, putative 0.0231 0.1361 0.2799
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0789 0.4861 0.4861
Schistosoma mansoni chromobox protein 0.0151 0.0859 0.0859
Schistosoma mansoni hypothetical protein 0.0133 0.0744 0.0744
Trichomonas vaginalis ran, putative 0.0021 0.0041 0.0114
Schistosoma mansoni smad 0.0016 0.0014 0.0014
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0041 0.0166 0.1567
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0288 0.0792
Mycobacterium tuberculosis Probable reductase 0.0094 0.0499 0.4719
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0075 0.0383 0.0383
Echinococcus granulosus calpain 0.0019 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0051 0.0231 0.0448
Loa Loa (eye worm) calpain family protein 1 0.0044 0.0189 0.0362
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0091 0.0859
Brugia malayi T-complex protein 1, beta subunit 0.0029 0.0094 0.0193
Schistosoma mansoni hypothetical protein 0.0287 0.171 0.171
Echinococcus multilocularis thioredoxin glutathione reductase 0.0042 0.0172 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0066 0.0285
Echinococcus multilocularis cathepsin b 0.0789 0.4861 0.4861
Mycobacterium ulcerans hypothetical protein 0.0041 0.0166 0.1567
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0133 0.0744 0.0744
Brugia malayi latrophilin 2 splice variant baaae 0.0287 0.171 0.3518
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0042 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Giardia lamblia Cysteine protease 0.006 0.0288 0.1692
Schistosoma mansoni chromobox protein 0.0151 0.0859 0.0859
Leishmania major cysteine peptidase A (CPA) 0.0226 0.1331 0.5537
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0181
Trypanosoma cruzi cysteine peptidase, putative 0.0397 0.2404 0.4945
Echinococcus granulosus cysteine protease 0.0128 0.0711 0.0711
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0291 0.08
Brugia malayi MH2 domain containing protein 0.0016 0.0014 0.0028
Brugia malayi nuclear receptor RXR 0.007 0.0347 0.0714
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0066 0.0386
Plasmodium falciparum thioredoxin reductase 0.0041 0.0169 0.1267
Echinococcus multilocularis calpain 0.0019 0.0029 0.0029
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.006 0.0288 0.2164
Echinococcus granulosus lysosomal alpha glucosidase 0.038 0.2294 0.2294
Loa Loa (eye worm) ctsf protein 0.0226 0.1331 0.2718
Brugia malayi hypothetical protein 0.0062 0.03 0.0618
Schistosoma mansoni zinc finger protein 0.0062 0.03 0.03
Onchocerca volvulus 0.0042 0.0174 0.034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0132 0.0737 0.1548
Leishmania major cathepsin L-like protease 0.0226 0.1331 0.5537
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0015
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0088 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0095 0.0262
Loa Loa (eye worm) T-complex protein 1 0.0029 0.0094 0.0166
Brugia malayi calpain family protein 1 0.0063 0.0307 0.0632
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0789 0.4861 0.4861
Brugia malayi nuclear hormone receptor 0.0132 0.0737 0.1515
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0104 0.0565 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.03 0.03
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0041 0.0085
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.0347 0.0714
Brugia malayi Papain family cysteine protease containing protein 0.006 0.0288 0.0593
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0099 0.0272
Brugia malayi RNA binding protein 0.0116 0.0636 0.1309
Echinococcus granulosus histone acetyltransferase MYST2 0.0048 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.0107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.1324 0.1324
Onchocerca volvulus Serine\/threonine kinase homolog 0.0061 0.0291 0.0593
Trypanosoma cruzi cysteine peptidase, putative 0.0397 0.2404 0.4945
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.006 0.0288 0.0792
Brugia malayi nuclear receptor NHR-88 0.0062 0.03 0.0618
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0099 0.0272
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0067 0.0506
Brugia malayi hypothetical protein 0.007 0.0349 0.0718
Schistosoma mansoni alpha-glucosidase 0.0327 0.1962 0.1962
Onchocerca volvulus 0.0017 0.002 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Echinococcus granulosus cathepsin l1 0.0226 0.1331 0.1331
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0029 0.0119
Brugia malayi nuclear hormone receptor family member odr-7 0.0062 0.03 0.0618
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0026 0.0074 0.0074
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0062 0.03 0.03
Echinococcus multilocularis calpain 7 (C02 family) 0.0019 0.0029 0.0029
Brugia malayi photoreceptor-specific nuclear receptor 0.0132 0.0737 0.1515
Onchocerca volvulus Huntingtin homolog 0.0121 0.0671 0.1406
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0286 0.1702 0.3502
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0132 0.0737 0.1492
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0291 0.08
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Brugia malayi Glycosyl hydrolases family 31 protein 0.0084 0.044 0.0904
Leishmania major importin beta-1 subunit, putative 0.0023 0.0055 0.0227
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.006 0.0288 0.0792
Plasmodium vivax heterochromatin protein 1, putative 0.0025 0.0066 0.0494
Loa Loa (eye worm) hypothetical protein 0.0287 0.171 0.35
Loa Loa (eye worm) papain family cysteine protease containing protein 0.006 0.0288 0.0566
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0397 0.2404 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Brugia malayi CXXC zinc finger family protein 0.0024 0.0062 0.0128
Leishmania major 4-coumarate:coa ligase-like protein 0.0041 0.0166 0.069
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.007 0.0347 0.0347
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0226 0.1331 0.2718
Loa Loa (eye worm) doublecortin family protein 0.0017 0.0015 0.0002
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0169 0.097 0.097
Echinococcus granulosus lamin dm0 0.0017 0.002 0.002
Schistosoma mansoni rab6-interacting 0.0017 0.0015 0.0015
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0062 0.03 0.03
Loa Loa (eye worm) nuclear hormone receptor 0.0062 0.03 0.0591
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.044 0.1208
Echinococcus multilocularis Protein lozenge 0.0095 0.0509 0.0509
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0067 0.0138
Schistosoma mansoni chromobox protein 0.0025 0.0066 0.0066
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0028 0.003
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.007 0.0347 0.0347
Brugia malayi cathepsin F-like cysteine proteinase 0.006 0.0288 0.0593
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.006 0.0288 0.0288
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.006 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0031 0.0108 0.0194
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0075 0.0383 0.2251
Echinococcus multilocularis lipoxygenase domain containing protein 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0181
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0066 0.0135
Trypanosoma brucei trypanothione reductase 0.0041 0.0169 0.0701
Schistosoma mansoni smad1 5 8 and 0.0016 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0226 0.1331 0.3658
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0291 0.08
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0041 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0132 0.0737 0.1492
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0132 0.0741 0.0741
Onchocerca volvulus Cathepsin F homolog 0.0226 0.1331 0.2823
Brugia malayi hypothetical protein 0.0032 0.0109 0.0224
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0055 0.015
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0013
Echinococcus multilocularis tumor protein p63 0.058 0.3548 0.3548
Plasmodium falciparum serine repeat antigen 7 0.006 0.0288 0.2164
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0053 0.0146
Trypanosoma brucei kinesin, putative 0.0019 0.0029 0.0119
Leishmania major cathepsin L-like protease 0.0397 0.2404 1
Schistosoma mansoni tar DNA-binding protein 0.0116 0.0636 0.0636
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0132 0.0737 0.0737
Onchocerca volvulus Huntingtin homolog 0.0121 0.0671 0.1406
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0226 0.1331 0.1331
Brugia malayi RNA, U transporter 1 0.0081 0.0416 0.0855
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0029 0.0119
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0029 0.0059
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0067 0.0067
Echinococcus multilocularis cathepsin L cysteine protease 0.0226 0.1331 0.1331
Loa Loa (eye worm) hypothetical protein 0.0132 0.0737 0.1492
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0053 0.0053
Onchocerca volvulus 0.0017 0.002 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0041 0.0166 0.0341
Giardia lamblia Cathepsin B precursor 0.006 0.0288 0.1692
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.017 0.0975 0.0975
Brugia malayi cathepsin F-like cysteine proteinase 0.0067 0.0333 0.0686
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.044 0.1208
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0328 0.0328
Echinococcus granulosus neutral alpha glucosidase AB 0.0084 0.044 0.044
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.03 0.0612
Leishmania major trypanothione reductase 0.0041 0.0169 0.0701
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0711 0.1954
Brugia malayi glutathione reductase 0.0041 0.0169 0.0347
Echinococcus granulosus cathepsin L cysteine proteinase 0.0226 0.1331 0.1331
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.003 0.0101 1
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0067 0.0067
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0066 0.0181
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.006 0.0288 0.0792
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0019 0.0029 0.0119
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0108 0.0296
Echinococcus multilocularis thyroid hormone receptor alpha 0.0132 0.0737 0.0737
Giardia lamblia Cathepsin B precursor 0.006 0.0288 0.1692
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0132 0.0737 0.0737
Toxoplasma gondii NAC domain-containing protein 0.0029 0.0095 0.056
Loa Loa (eye worm) hypothetical protein 0.007 0.0347 0.0688
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0132 0.0737 0.0737
Brugia malayi jmjC domain containing protein 0.0025 0.0067 0.0138
Schistosoma mansoni cathepsin B (C01 family) 0.006 0.0288 0.0288
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0066 0.0494
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0029 0.0059
Schistosoma mansoni nuclear hormone receptor 0.0062 0.03 0.03
Brugia malayi Papain family cysteine protease containing protein 0.0128 0.0711 0.1462
Leishmania major 4-coumarate:coa ligase-like protein 0.0041 0.0166 0.069
Loa Loa (eye worm) ICD-1 protein 0.0029 0.0095 0.0168
Schistosoma mansoni lozenge 0.0095 0.0509 0.0509
Trypanosoma brucei antigen, putative 0.0019 0.0029 0.0119
Schistosoma mansoni hypothetical protein 0.0933 0.5763 0.5763
Giardia lamblia Hypothetical protein 0.006 0.0288 0.1692
Brugia malayi TAR-binding protein 0.0116 0.0636 0.1309
Brugia malayi Thioredoxin reductase 0.0041 0.0169 0.0347
Entamoeba histolytica acyl-CoA synthetase, putative 0.0041 0.0166 0.1053
Entamoeba histolytica papain family cysteine protease domain containing protein 0.006 0.0288 0.1992
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0029 0.0059
Loa Loa (eye worm) hypothetical protein 0.006 0.0288 0.0566
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0053 0.0399
Echinococcus multilocularis chromobox protein 1 0.0151 0.0859 0.0859
Schistosoma mansoni lipoxygenase 0.0017 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0169 0.097 0.1995
Entamoeba histolytica cysteine proteinase, putative 0.0128 0.0711 0.5238
Onchocerca volvulus 0.01 0.0538 0.1123
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0063 0.0307 0.0606
Echinococcus granulosus tar DNA binding protein 0.0116 0.0636 0.0636
Entamoeba histolytica Ran family GTPase 0.0021 0.0041 0.0097
Onchocerca volvulus 0.0024 0.0062 0.0102
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.044 0.1208
Loa Loa (eye worm) papain family cysteine protease containing protein 0.006 0.0288 0.0566
Echinococcus multilocularis lamin 0.0017 0.002 0.002
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0066 0.0386
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0132 0.0737 0.0737
Trypanosoma cruzi cysteine peptidase, putative 0.0397 0.2404 0.4945
Brugia malayi SET domain containing protein 0.0028 0.0086 0.0178
Echinococcus granulosus cathepsin l1 0.0159 0.0908 0.0908
Brugia malayi jmjC domain containing protein 0.0025 0.0067 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.1331 0.3658
Echinococcus granulosus neuropeptide s receptor 0.0457 0.2779 0.2779
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0094 0.0499 0.4719
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0029 0.0119
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0066 0.0066
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0067 0.0138
Giardia lamblia Cathepsin L precursor 0.006 0.0288 0.1692
Schistosoma mansoni cpg binding protein 0.0026 0.0071 0.0071
Plasmodium vivax importin-beta 2, putative 0.0028 0.0088 0.0663
Schistosoma mansoni cathepsin F (C01 family) 0.0159 0.0908 0.0908
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0226 0.1331 0.3658
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0053 0.0399
Plasmodium falciparum basic transcription factor 3b, putative 0.0029 0.0095 0.0716
Echinococcus granulosus lipoxygenase domain containing protein 0.0017 0.0015 0.0015
Echinococcus multilocularis lysine specific demethylase 5A 0.0094 0.0498 0.0498
Onchocerca volvulus Cathepsin L homolog 0.006 0.0288 0.0586
Loa Loa (eye worm) CHromoDomain protein family member 0.0026 0.0074 0.0125
Echinococcus multilocularis lysosomal alpha glucosidase 0.038 0.2294 0.2294
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.1058 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.006 0.0288 0.0792
Brugia malayi MH2 domain containing protein 0.0241 0.1424 0.2929
Plasmodium vivax vivapain-1 0.0128 0.0711 0.5341
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0029 0.0094 0.0094
Giardia lamblia Cysteine protease 0.006 0.0288 0.1692
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0128 0.0711 0.1462
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.006 0.0288 0.0288
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0067 0.0067
Leishmania major glycosyl hydrolase-like protein 0.0031 0.0108 0.0448
Brugia malayi jmjC domain containing protein 0.0025 0.0067 0.0138
Schistosoma mansoni hypothetical protein 0.0259 0.1538 0.1538
Echinococcus multilocularis peregrin 0.0019 0.0028 0.0028
Trichomonas vaginalis maltase-glucoamylase, putative 0.0084 0.044 0.1208
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0014 0.0014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0225 0.1324 0.1324
Loa Loa (eye worm) thioredoxin reductase 0.0041 0.0169 0.032
Plasmodium falciparum cysteine proteinase falcipain 1 0.0128 0.0711 0.5341
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0288 0.0792
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0159 0.0908 0.2496
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.044 0.0904
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.006 0.0288 0.0792
Schistosoma mansoni transcription factor btf3 0.0029 0.0095 0.0095
Toxoplasma gondii histone lysine methyltransferase SET1 0.0049 0.0215 0.1265
Giardia lamblia Kinase, PLK 0.0061 0.0291 0.171
Loa Loa (eye worm) hypothetical protein 0.0062 0.03 0.0591
Echinococcus granulosus geminin 0.0933 0.5763 0.5763
Echinococcus granulosus intermediate filament protein 0.0017 0.002 0.002
Echinococcus granulosus FTZ F1 alpha 0.0132 0.0737 0.0737
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.006 0.0288 0.1692
Loa Loa (eye worm) pigment dispersing factor receptor c 0.042 0.2543 0.5218
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.1058 1
Entamoeba histolytica cysteine proteinase, putative 0.0226 0.1331 1
Loa Loa (eye worm) hypothetical protein 0.076 0.4678 0.9622
Plasmodium vivax SET domain protein, putative 0.0075 0.0383 0.2879

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.01 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 1.4125 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: Inhibitors of TCP-1 ring complex (TRiC) of Methanococcus maripaludis (MmCpn): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488991] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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