Detailed information for compound 1146095

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 479.492 | Formula: C24H28F3N3O4
  • H donors: 0 H acceptors: 2 LogP: 5.11 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H]1[C@H](O[C@H]2[C@@]34[C@H]1CC[C@H]([C@@H]4CC[C@@](O2)(OO3)C)C)n1nnc(c1)c1ccccc1C(F)(F)F
  • InChi: 1S/C24H28F3N3O4/c1-13-8-9-17-14(2)20(31-21-23(17)16(13)10-11-22(3,32-21)33-34-23)30-12-19(28-29-30)15-6-4-5-7-18(15)24(25,26)27/h4-7,12-14,16-17,20-21H,8-11H2,1-3H3/t13-,14+,16+,17+,20+,21-,22+,23-/m1/s1
  • InChiKey: SOVRCGPSPHNVJB-NDKCXKIMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus endothelin converting enzyme 1 0.2869 0.3165 1
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0005 0.0005
Schistosoma mansoni amine GPCR 0.0095 0.0078 0.0245
Brugia malayi PDZ domain containing protein 0.0026 0.0001 0.0001
Brugia malayi hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi steroid hormone receptor 0.0062 0.0041 0.0041
Leishmania major cathepsin L-like protease 0.0216 0.0213 1
Brugia malayi Cathepsin L-like precursor 0.0116 0.0101 0.0101
Onchocerca volvulus 0.0033 0.0009 0.0056
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0041 0.0041
Loa Loa (eye worm) MH2 domain-containing protein 0.0773 0.0832 0.0832
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0032 0.0099
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0038 0.1578
Loa Loa (eye worm) hypothetical protein 0.2206 0.2426 0.2426
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0007
Schistosoma mansoni growth hormone secretagogue receptor 0.0095 0.0078 0.0245
Brugia malayi putative neuropeptide receptor 0.0095 0.0078 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0196 0.0619
Brugia malayi larval opioid receptor 0.0095 0.0078 0.0078
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0059 0.2453
Loa Loa (eye worm) hypothetical protein 0.0159 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0082 0.0063 0.0063
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0031 0.1071
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.006 0.2501
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0014 0.0045
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.006 0.0178
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0005 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0062 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0095 0.0078 0.0245
Trypanosoma cruzi cysteine peptidase, putative 0.0116 0.0101 0.2117
Echinococcus granulosus Sterile alpha motif type 0.0044 0.0021 0.0066
Brugia malayi Fibronectin type III domain containing protein 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0067 0.0047 0.0047
Echinococcus granulosus allatostatin A receptor 0.0095 0.0078 0.0245
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0209 0.0204 0.0645
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0038 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0066 0.0045 0.0793
Schistosoma mansoni titin 0.0033 0.0009 0.0028
Plasmodium falciparum serine repeat antigen 8 0.0032 0.0007 0.0333
Loa Loa (eye worm) neuropeptide F receptor 0.0095 0.0078 0.0078
Trypanosoma cruzi cruzipain precursor, putative 0.0216 0.0213 0.4569
Echinococcus multilocularis Netrin receptor DCC 0.0033 0.0009 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Echinococcus multilocularis polyhomeotic proximal chromatin protein 0.0044 0.0021 0.0066
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Giardia lamblia Cysteine protease 0.0032 0.0007 0.0226
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0005 0.0005
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.1374 0.1501 0.4744
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0033 0.0009 0.0028
Echinococcus multilocularis somatostatin receptor 0.0095 0.0078 0.0245
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.1374 0.1501 0.4744
Plasmodium vivax serine-repeat antigen (SERA) 0.0032 0.0007 0.0333
Schistosoma mansoni survival motor neuron protein 0.0104 0.0087 0.0275
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Brugia malayi RNA recognition motif domain containing protein 0.0201 0.0196 0.0196
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0034 0.001 0.001
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.2869 0.3165 0.3164
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Schistosoma mansoni neuropeptide receptor 0.0198 0.0193 0.0608
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0014 0.0044
Loa Loa (eye worm) zinc metallopeptidase 4 0.0664 0.071 0.071
Echinococcus granulosus neuropeptide Y receptor 0.0095 0.0078 0.0245
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0014 0.025
Onchocerca volvulus 0.0106 0.009 0.0548
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0012 0.0035
Schistosoma mansoni cathepsin F (C01 family) 0.0082 0.0063 0.0199
Onchocerca volvulus 0.0854 0.0922 0.564
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Schistosoma mansoni nephrin 0.0033 0.0009 0.0028
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0157 0.0147 0.3124
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0032 0.0007 0.0333
Brugia malayi PAS domain containing protein 0.0054 0.0032 0.0032
Echinococcus granulosus g protein coupled receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0044 0.0021 0.0021
Brugia malayi Dopamine receptor 0.0095 0.0078 0.0078
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.0078 0.0245
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0005 0.0014
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0095 0.0078 0.0476
Schistosoma mansoni opsin-like receptor 0.0095 0.0078 0.0245
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0066 0.0045 0.0143
Brugia malayi G protein-coupled receptor F59B2.13 0.0095 0.0078 0.0078
Toxoplasma gondii cathepsin CPC2 0.0032 0.0007 0.001
Schistosoma mansoni smad 0.0053 0.0031 0.0096
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.0242 0.0724
Echinococcus multilocularis orexin receptor type 2 0.0095 0.0078 0.0245
Brugia malayi cask-interacting protein 2 0.0044 0.0021 0.0021
Schistosoma mansoni inositol monophosphatase 0.0078 0.0059 0.0186
Echinococcus multilocularis serotonin receptor 0.0095 0.0078 0.0245
Schistosoma mansoni spingomyelin synthetase-related 0.0044 0.0021 0.0066
Plasmodium vivax vivapain-2 0.0116 0.0101 1
Schistosoma mansoni cell adhesion molecule 0.0033 0.0009 0.0028
Echinococcus multilocularis lysosomal alpha glucosidase 0.0183 0.0175 0.0553
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0045 0.1779
Echinococcus granulosus neuropeptide s receptor 0.0095 0.0078 0.0245
Toxoplasma gondii aldehyde dehydrogenase 0.0209 0.0204 0.0634
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0062 0.0041 0.0041
Leishmania major alpha glucosidase II subunit, putative 0.0041 0.0017 0.0572
Loa Loa (eye worm) hypothetical protein 0.0082 0.0063 0.0063
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0014 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0014 0.02
Loa Loa (eye worm) hypothetical protein 0.0049 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0095 0.0078 0.0476
Loa Loa (eye worm) fibroinase 0.0116 0.0101 0.0101
Schistosoma mansoni ap endonuclease 0.0059 0.0038 0.0119
Brugia malayi Peptidase family M13 containing protein 0.2869 0.3165 0.3165
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0009 0.0009
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0033 0.0009 0.0028
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0005 0.0014
Onchocerca volvulus 0.0095 0.0078 0.0476
Leishmania major hypothetical protein, conserved 0.0079 0.006 0.2646
Echinococcus granulosus G1Y162 protein 0.0033 0.0009 0.0028
Schistosoma mansoni hypothetical protein 0.0711 0.0763 0.2411
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0062 0.0041 0.0041
Leishmania major hypothetical protein, conserved 0.0033 0.0009 0.0193
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.0078 0.0245
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Echinococcus granulosus cathepsin l cysteine peptidase 0.0116 0.0101 0.0319
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0095 0.0078 0.0245
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Echinococcus multilocularis geminin 0.0547 0.058 0.1832
Plasmodium falciparum conserved protein, unknown function 0.0084 0.0066 0.6341
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0438 0.046 0.1451
Plasmodium vivax cysteine repeat modular protein 2, putative 0.0084 0.0066 0.6341
Brugia malayi Serotonin receptor 0.0095 0.0078 0.0078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Brugia malayi hypothetical protein 0.0095 0.0078 0.0078
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0438 0.046 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0062 0.0041 0.013
Giardia lamblia Cathepsin B precursor 0.0157 0.0147 1
Brugia malayi CXXC zinc finger family protein 0.0059 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Echinococcus granulosus anosmin 1 0.0033 0.0009 0.0028
Echinococcus multilocularis cell adhesion molecule 0.0033 0.0009 0.0028
Brugia malayi RE15519p 0.0095 0.0078 0.0078
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0095 0.0078 0.0078
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0031 0.0097
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0033 0.0009 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Onchocerca volvulus Cathepsin F homolog 0.0116 0.0101 0.062
Leishmania major cathepsin L-like protease 0.0116 0.0101 0.4634
Echinococcus multilocularis endothelin converting enzyme 1 0.2869 0.3165 1
Loa Loa (eye worm) projectin 0.0033 0.0009 0.0009
Onchocerca volvulus 0.0071 0.0051 0.0309
Toxoplasma gondii preprocathepsin c precursor, putative 0.0032 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Trypanosoma cruzi Kinesin-13 5, putative 0.0044 0.0021 0.0354
Schistosoma mansoni tripartite motif protein trim9 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.006 0.5762
Brugia malayi beta-lactamase family protein 0.0038 0.0014 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0017 0.0204
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0038 0.0038
Echinococcus granulosus geminin 0.0547 0.058 0.1832
Echinococcus granulosus survival motor neuron protein 1 0.0508 0.0537 0.1696
Echinococcus granulosus roundabout 2 0.0033 0.0009 0.0028
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0005 0.0014
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0062 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0104 0.0087 0.0275
Loa Loa (eye worm) hypothetical protein 0.2206 0.2426 0.2426
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.001 0.001
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0033 0.0009 0.0088
Loa Loa (eye worm) hypothetical protein 0.0084 0.0065 0.0065
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0032 0.0007 0.0022
Echinococcus multilocularis endonuclease reverse transcriptase 0.0084 0.0066 0.0207
Schistosoma mansoni smad1 5 8 and 0.0053 0.0031 0.0096
Brugia malayi Papain family cysteine protease containing protein 0.0066 0.0045 0.0045
Echinococcus multilocularis allatostatin A receptor 0.0095 0.0078 0.0245
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0032 0.0007 0.0333
Onchocerca volvulus 0.0159 0.0149 0.0911
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0038 0.012
Brugia malayi bHLH-PAS transcription factor 0.004 0.0016 0.0016
Echinococcus granulosus pdz domain containing protein 0.0044 0.0021 0.0066
Brugia malayi Fibronectin type III domain containing protein 0.0033 0.0009 0.0009
Echinococcus granulosus GPCR family 2 0.0118 0.0103 0.0326
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Schistosoma mansoni titin 0.0033 0.0009 0.0028
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0044 0.0021 0.0066
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0033 0.0009 0.0028
Brugia malayi Sphingomyelin synthase-related 1 0.0044 0.0021 0.0021
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0116 0.0101 0.0319
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0301 0.0307 0.0969
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0066 0.0045 0.0793
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0004 0.0004
Plasmodium vivax serine-repeat antigen (SERA) 0.0032 0.0007 0.0333
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0664 0.071 0.2244
Onchocerca volvulus 0.0033 0.0009 0.0056
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0005 0.0004
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0095 0.0078 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0116 0.0101 0.1957
Echinococcus multilocularis Fibronectin type III domain containing protein 0.0033 0.0009 0.0028
Schistosoma mansoni hypothetical protein 0.0033 0.0009 0.0028
Entamoeba histolytica cysteine proteinase, putative 0.0082 0.0063 0.5946
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Brugia malayi Papain family cysteine protease containing protein 0.0116 0.0101 0.0101
Schistosoma mansoni alpha-1 adrenergic receptor 0.0095 0.0078 0.0245
Schistosoma mansoni alpha-glucosidase 0.0157 0.0147 0.0463
Echinococcus multilocularis G protein coupled receptor 139 0.0198 0.0193 0.0608
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0062 0.0041 0.013
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0062 0.0041 0.0041
Echinococcus granulosus EG95 0.0033 0.0009 0.0028
Onchocerca volvulus 0.0033 0.0009 0.0056
Plasmodium falciparum serine repeat antigen 3 0.0032 0.0007 0.0333
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0009 0.0026
Echinococcus granulosus liprin alpha 2 0.0044 0.0021 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0038 0.3262
Loa Loa (eye worm) DR-78 0.0029 0.0005 0.0004
Leishmania major cathepsin L-like protease 0.0116 0.0101 0.4634
Trichomonas vaginalis esterase, putative 0.0038 0.0014 0.0146
Loa Loa (eye worm) hypothetical protein 0.0039 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Brugia malayi protein unc-22 0.0034 0.001 0.001
Entamoeba histolytica hypothetical protein, conserved 0.0084 0.0066 0.6215
Echinococcus granulosus 7TM GPCR rhodopsin 0.0095 0.0078 0.0245
Onchocerca volvulus 0.0095 0.0078 0.0476
Echinococcus granulosus cathepsin L 0.0066 0.0045 0.0143
Echinococcus multilocularis titin 0.0034 0.001 0.003
Brugia malayi Cathepsin L-like precursor 0.0116 0.0101 0.0101
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0032 0.0007 0.0333
Echinococcus granulosus neuropeptide receptor A26 0.0095 0.0078 0.0245
Brugia malayi GCC2 and GCC3 family protein 0.0084 0.0066 0.0066
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0009 0.0009
Echinococcus multilocularis Phosphotidylinositol phosphatase PTPRQ 0.0033 0.0009 0.0028
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Brugia malayi cathepsin F-like cysteine proteinase 0.0034 0.001 0.001
Schistosoma mansoni smad1 5 8 and 0.0053 0.0031 0.0096
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0062 0.0041 0.0041
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.0017 0.0204
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0062 0.0041 0.013
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0017 0.0204
Schistosoma mansoni hypothetical protein 0.0711 0.0763 0.2411
Brugia malayi Cathepsin L-like precursor 0.0034 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0063 0.1163
Loa Loa (eye worm) hypothetical protein 0.0508 0.0537 0.0537
Onchocerca volvulus 0.0116 0.0101 0.062
Brugia malayi Latrophilin receptor protein 2 0.0118 0.0103 0.0103
Trypanosoma brucei cysteine peptidase C (CPC) 0.0157 0.0147 0.6776
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0009 0.0009
Echinococcus granulosus fmrfamide receptor 0.0095 0.0078 0.0245
Schistosoma mansoni neuropeptide F-like receptor 0.0095 0.0078 0.0245
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0038 0.012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0014 0.0014
Onchocerca volvulus 0.0464 0.0488 0.2987
Echinococcus multilocularis pdz domain containing protein 0.0044 0.0021 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Schistosoma mansoni neuropeptide receptor 0.0095 0.0078 0.0245
Brugia malayi Fibronectin type III domain containing protein 0.0033 0.0009 0.0009
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0084 0.0066 0.6341
Brugia malayi nuclear receptor NHR-67 0.0029 0.0005 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0017 0.0204
Toxoplasma gondii exonuclease III APE 0.0059 0.0038 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Echinococcus multilocularis histone acetyltransferase myst3 0.0048 0.0025 0.0078
Loa Loa (eye worm) nuclear factor I 0.0029 0.0004 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0038 0.0638
Schistosoma mansoni biogenic amine (5HT) receptor 0.0095 0.0078 0.0245
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.2869 0.3165 0.3165
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi neuropeptide F receptor 0.0095 0.0078 0.0078
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0209 0.0204 0.0645
Onchocerca volvulus 0.0033 0.0009 0.0056
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0062 0.0041 0.013
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0373 0.0388 0.0387
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0095 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0078 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.0101 0.1957
Brugia malayi hypothetical protein 0.0095 0.0078 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Onchocerca volvulus 0.1495 0.1635 1
Onchocerca volvulus 0.0095 0.0078 0.0476
Trypanosoma cruzi cysteine peptidase, putative 0.0216 0.0213 0.4569
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0059 0.2598
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0007 0.0007
Onchocerca volvulus 0.0104 0.0087 0.0533
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.0067 0.0047 0.0148
Schistosoma mansoni neuropeptide receptor 0.0095 0.0078 0.0245
Schistosoma mansoni neuropeptide f receptor 76f 0.0095 0.0078 0.0245
Echinococcus granulosus serotonin receptor 0.0095 0.0078 0.0245
Echinococcus granulosus liprin alpha 2 0.0067 0.0047 0.0148
Brugia malayi hypothetical protein 0.0051 0.0029 0.0029
Leishmania major hypothetical protein, conserved 0.0038 0.0014 0.0438
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0095 0.0078 0.0245
Schistosoma mansoni cell adhesion molecule 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0017
Echinococcus granulosus neuropeptide receptor 0.0198 0.0193 0.0608
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0014 0.0044
Onchocerca volvulus 0.0116 0.0101 0.062
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0116 0.0101 1
Echinococcus granulosus Netrin receptor DCC 0.0033 0.0009 0.0028
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0077 0.0242
Trypanosoma brucei SAM domain (Sterile alpha motif), putative 0.0044 0.0021 0.0593
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.0101 0.1957
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0078 0.0245
Echinococcus granulosus neuroglian 0.0033 0.0009 0.0028
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.2206 0.2426 0.2426
Trypanosoma cruzi cysteine peptidase, putative 0.0216 0.0213 0.4569
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Onchocerca volvulus 0.0033 0.0009 0.0056
Toxoplasma gondii kringle domain-containing protein 0.0084 0.0066 0.0195
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0095 0.0078 0.0245
Onchocerca volvulus Bile acid receptor homolog 0.0062 0.0041 0.0253
Entamoeba histolytica cysteine proteinase, putative 0.0116 0.0101 1
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0032 0.0007 0.0333
Echinococcus multilocularis neuroglian 0.0033 0.0009 0.0028
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi ecdysone receptor 0.0029 0.0005 0.0005
Brugia malayi cathepsin Z-like cysteine proteinase 0.0032 0.0007 0.0007
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0095 0.0078 0.0245
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0438 0.046 0.1451
Loa Loa (eye worm) TYRA-2 protein 0.0095 0.0078 0.0078
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0031 0.0097
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0014 0.0146
Loa Loa (eye worm) hypothetical protein 0.0039 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0062 0.0041 0.0041
Onchocerca volvulus 0.0084 0.0065 0.0398
Onchocerca volvulus 0.0033 0.0009 0.0056
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0005 0.0014
Echinococcus granulosus cpg binding protein 0.0062 0.0041 0.0129
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0053 0.0031 0.0096
Schistosoma mansoni alpha glucosidase 0.0041 0.0017 0.0053
Plasmodium falciparum protein kinase, putative 0.0032 0.0007 0.0308
Echinococcus multilocularis roundabout 2 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0007
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0032 0.0007 0.0007
Echinococcus multilocularis Sterile alpha motif type 0.0044 0.0021 0.0066
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0033 0.0009 0.0028
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0077 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0062 0.0041 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0062 0.0041 0.0041
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0095 0.0078 0.0078
Echinococcus multilocularis tar DNA binding protein 0.0201 0.0196 0.0619
Entamoeba histolytica hypothetical protein 0.0084 0.0066 0.6215
Loa Loa (eye worm) hypothetical protein 0.0084 0.0066 0.0065
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0032 0.0007 0.0333
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0059 0.5512
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.006 0.5762
Brugia malayi Pre-SET motif family protein 0.0408 0.0426 0.0426
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0033 0.0009 0.0028
Plasmodium falciparum cysteine repeat modular protein 3 0.0084 0.0066 0.6341
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.2206 0.2426 0.2426
Echinococcus granulosus cell adhesion molecule 0.0033 0.0009 0.0028
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0017 0.0204
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0041 0.0017 0.0041
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0005 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Trypanosoma cruzi major cysteine proteinase, putative 0.0132 0.0119 0.2497
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Echinococcus multilocularis liprin alpha 2 0.0067 0.0047 0.0148
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0118 0.0103 0.0326
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0118 0.0103 0.0326
Plasmodium vivax hypothetical protein, conserved 0.0084 0.0066 0.6341
Onchocerca volvulus 0.0038 0.0014 0.0087
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0044 0.0021 0.013
Loa Loa (eye worm) hypothetical protein 0.2869 0.3165 0.3164
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0016 0.005
Brugia malayi bicaudal-C 0.0044 0.0021 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0041 0.013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Onchocerca volvulus 0.0033 0.0009 0.0056
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0045 0.0885
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0014 0.1056
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0032 0.0007 0.0333
Loa Loa (eye worm) hypothetical protein 0.0062 0.0041 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Schistosoma mansoni neuropeptide F-like receptor 0.0095 0.0078 0.0245
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0014 0.0014
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0032 0.0007 0.0022
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0062 0.0041 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Brugia malayi Intermediate filament tail domain containing protein 0.0084 0.0065 0.0065
Brugia malayi TAR-binding protein 0.0201 0.0196 0.0196
Echinococcus granulosus ephrin type A receptor 4 A 0.0947 0.1025 0.3239
Onchocerca volvulus 0.0029 0.0005 0.0029
Onchocerca volvulus 0.0044 0.0021 0.013
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0038 0.0119
Echinococcus granulosus somatostatin receptor 0.0095 0.0078 0.0245
Schistosoma mansoni hypothetical protein 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0079 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0438 0.046 0.0459
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0062 0.0041 0.0253
Echinococcus granulosus hypothetical protein 0.0095 0.0078 0.0245
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0116 0.0101 0.0101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0062 0.0041 0.013
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.0017 0.0017
Plasmodium vivax vivapain-1 0.0066 0.0045 0.4252
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0009 0.0088
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Echinococcus granulosus usherin 0.0033 0.0009 0.0028
Toxoplasma gondii cathepsin CPL 0.0116 0.0101 0.0308
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0066 0.0045 0.0885
Leishmania major cysteine peptidase A (CPA) 0.0116 0.0101 0.4634
Schistosoma mansoni inositol monophosphatase 0.0078 0.0059 0.0186
Mycobacterium ulcerans zinc metalloprotease 0.2869 0.3165 1
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0232 0.023 0.0726
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0012 0.0035
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.006 0.1209
Onchocerca volvulus 0.0095 0.0078 0.0476
Onchocerca volvulus 0.0084 0.0065 0.0398
Schistosoma mansoni cathepsin B (C01 family) 0.0032 0.0007 0.0022
Schistosoma mansoni protein tyrosine phosphatase 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0008
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0438 0.046 0.1451
Onchocerca volvulus 0.0062 0.0041 0.0253
Brugia malayi Protein-tyrosine phosphatase 0.0033 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Echinococcus multilocularis 0.0035 0.0011 0.0035
Loa Loa (eye worm) G-protein coupled receptor 0.0095 0.0078 0.0078
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0005 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Plasmodium vivax vivapain-2 0.0116 0.0101 1
Brugia malayi Dopamine receptor protein 1 0.0095 0.0078 0.0078
Echinococcus granulosus endonuclease reverse transcriptase 0.0084 0.0066 0.0207
Loa Loa (eye worm) TAR-binding protein 0.0201 0.0196 0.0196
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.0078 0.0245
Schistosoma mansoni Protein aveugle 0.0044 0.0021 0.0066
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0095 0.0078 0.0078
Brugia malayi Fibronectin type III domain containing protein 0.0033 0.0009 0.0009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0095 0.0078 0.0078
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0031 0.0031
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0055 0.0174
Trypanosoma cruzi cysteine proteinase, putative 0.0066 0.0045 0.0885
Giardia lamblia Cathepsin L-like protease 0.0032 0.0007 0.0226
Plasmodium falciparum serine repeat antigen 2 0.0032 0.0007 0.0333
Entamoeba histolytica cysteine proteinase, putative 0.0116 0.0101 1
Echinococcus multilocularis Smad4 0.0053 0.0031 0.0096
Onchocerca volvulus 0.0084 0.0066 0.0402
Mycobacterium ulcerans aldehyde dehydrogenase 0.0209 0.0204 0.0603
Schistosoma mansoni cell adhesion molecule 0.0033 0.0009 0.0028
Brugia malayi Nuclear hormone receptor-like 1 0.0062 0.0041 0.0041
Brugia malayi hypothetical protein 0.0033 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0095 0.0078 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.0101 0.1957
Plasmodium vivax hypothetical protein, conserved 0.0084 0.0066 0.6341
Mycobacterium ulcerans aldehyde dehydrogenase 0.0209 0.0204 0.0603
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0062 0.0041 0.0041
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0032 0.0007 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.001 0.003
Brugia malayi Steroid receptor seven-up type 2 0.0062 0.0041 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0041 0.0041
Schistosoma mansoni cathepsin F (C01 family) 0.0116 0.0101 0.0319
Brugia malayi putative neuropeptide receptor NPR1 0.0095 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi cathepsin F-like cysteine proteinase 0.0032 0.0007 0.0007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0062 0.0041 0.013
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Plasmodium vivax protein kinase, putative 0.0053 0.0031 0.2728
Brugia malayi hypothetical protein 0.0029 0.0005 0.0005
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.005 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Entamoeba histolytica hypothetical protein 0.0084 0.0066 0.6215
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0008
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0031 0.1243
Brugia malayi MH1 domain containing protein 0.0029 0.0004 0.0004
Loa Loa (eye worm) inositol-1 0.0078 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0038 0.012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0078 0.0245
Loa Loa (eye worm) lethal protein 805 0.0033 0.0009 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0066 0.0045 0.4054
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Giardia lamblia Cathepsin B precursor 0.0032 0.0007 0.0226
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0009 0.0026
Echinococcus granulosus tumor protein p63 0.1087 0.1181 0.3732
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0301 0.0307 0.0969
Brugia malayi Liprin-alpha 2 0.0067 0.0047 0.0047
Echinococcus granulosus biogenic amine 5HT receptor 0.0095 0.0078 0.0245
Brugia malayi GCC2 and GCC3 family protein 0.0084 0.0066 0.0066
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0062 0.0041 0.0041
Echinococcus granulosus cathepsin l1 0.0082 0.0063 0.0199
Echinococcus multilocularis anosmin 1 0.0033 0.0009 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0196 0.0619
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0017 0.0204
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0038 0.012
Echinococcus multilocularis g protein coupled receptor 0.0095 0.0078 0.0245
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0845 0.0913 0.2883
Echinococcus multilocularis anosmin 1 0.0033 0.0009 0.0028
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0004 0.0012
Plasmodium falciparum serine repeat antigen 4 0.0032 0.0007 0.0333
Entamoeba histolytica protein kinase, putative 0.0085 0.0066 0.6272
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0005 0.0029
Brugia malayi MH2 domain containing protein 0.0053 0.0031 0.0031
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0059 0.0174
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0032 0.0007 0.0007
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0014 0.0014
Echinococcus granulosus neuropeptide Y receptor 0.0095 0.0078 0.0245
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.0078 0.0245
Brugia malayi Lethal protein 805 0.0033 0.0009 0.0009
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0095 0.0078 0.0245
Brugia malayi hypothetical protein 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.0101 0.1957
Echinococcus granulosus Smad4 0.0053 0.0031 0.0096
Brugia malayi conserved hypotetical protein 0.0029 0.0005 0.0005
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0032 0.0007 0.0022
Schistosoma mansoni neuroglian 0.0033 0.0009 0.0028
Mycobacterium ulcerans aldehyde dehydrogenase 0.0209 0.0204 0.0603
Echinococcus granulosus cysteine protease 0.0066 0.0045 0.0143
Echinococcus granulosus polyhomeotic proximal chromatin protein 0.0044 0.0021 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0007
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0104 0.0087 0.0087
Trichomonas vaginalis sucrase-isomaltase, putative 0.0041 0.0017 0.0204
Echinococcus multilocularis lamin 0.0084 0.0065 0.0205
Schistosoma mansoni hypothetical protein 0.0711 0.0763 0.2411
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Schistosoma mansoni sex comb on midleg homolog 0.0044 0.0021 0.0066
Onchocerca volvulus 0.0044 0.0021 0.013
Echinococcus multilocularis neuropeptide FF receptor 2 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0095 0.0078 0.0245
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0042 0.0019 0.0058
Echinococcus multilocularis polyhomeotic protein 2 0.0044 0.0021 0.0066
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Leishmania major cathepsin L-like protease 0.0216 0.0213 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0157 0.0147 0.6838
Brugia malayi nuclear receptor NHR-88 0.0029 0.0005 0.0005
Brugia malayi ecdysteroid receptor 0.0062 0.0041 0.0041
Echinococcus multilocularis cathepsin L cysteine protease 0.0116 0.0101 0.0319
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0301 0.0307 0.0969
Brugia malayi ephrin receptor 1 precursor 0.0427 0.0448 0.0448
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0032 0.0007 0.0333
Schistosoma mansoni hypothetical protein 0.0118 0.0103 0.0326
Onchocerca volvulus 0.0095 0.0078 0.0476
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0033 0.0009 0.0028
Brugia malayi Inositol-1 0.0078 0.0059 0.0059
Loa Loa (eye worm) cathepsin B 0.0157 0.0147 0.0147
Schistosoma mansoni endothelin-converting enzyme-related 0.0664 0.071 0.2244
Brugia malayi hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0118 0.0103 0.0103
Echinococcus granulosus roundabout 2 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0301 0.0307 0.0969
Echinococcus granulosus anosmin 1 0.0033 0.0009 0.0028
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0084 0.0066 0.0065
Onchocerca volvulus 0.0038 0.0014 0.0087
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0038 0.0075
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0255 0.0256 0.0808
Brugia malayi RNA binding protein 0.0201 0.0196 0.0196
Onchocerca volvulus 0.0044 0.0021 0.013
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0022 0.0022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0041 0.013
Echinococcus multilocularis cathepsin b 0.0438 0.046 0.1451
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0095 0.0078 0.0245
Echinococcus granulosus g protein coupled receptor 0.0095 0.0078 0.0245
Brugia malayi hypothetical protein 0.0095 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0453 0.0476 0.0475
Loa Loa (eye worm) neuropeptide F receptor 0.0095 0.0078 0.0078
Echinococcus granulosus dnaJ subfamily B 0.0837 0.0903 0.2854
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0201 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Brugia malayi POT family protein 0.026 0.0262 0.0262
Echinococcus multilocularis roundabout 2 0.0033 0.0009 0.0028
Brugia malayi GCC2 and GCC3 family protein 0.0084 0.0066 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0078 0.0245
Schistosoma mansoni single-minded 0.0054 0.0032 0.0099
Echinococcus multilocularis chromobox protein 2 0.0189 0.0182 0.0574
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0062 0.0041 0.013
Echinococcus multilocularis cysteine protease 0.0116 0.0101 0.0319
Brugia malayi hypothetical protein 0.0095 0.0078 0.0078
Trypanosoma cruzi hypothetical protein 0.0044 0.0021 0.0354
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0095 0.0078 0.0476
Leishmania major cathepsin L-like protease 0.0116 0.0101 0.4634
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0005 0.0014
Giardia lamblia Cysteine protease 0.0032 0.0007 0.0226
Schistosoma mansoni hemicentin 0.0033 0.0009 0.0028
Echinococcus multilocularis fmrfamide receptor 0.0095 0.0078 0.0245
Schistosoma mansoni steroid hormone receptor ad4bp 0.0062 0.0041 0.013
Echinococcus multilocularis smad 0.0053 0.0031 0.0096
Loa Loa (eye worm) hypoxia-induced factor 1 0.0166 0.0157 0.0156
Brugia malayi Papain family cysteine protease containing protein 0.0066 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0007
Echinococcus multilocularis neuropeptides capa receptor 0.0095 0.0078 0.0245
Schistosoma mansoni amine GPCR 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi hypothetical protein 0.0079 0.006 0.006
Echinococcus multilocularis GPCR, family 2 0.0118 0.0103 0.0326
Schistosoma mansoni Smad4 0.0053 0.0031 0.0096
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0009 0.0026
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0014 0.0014
Echinococcus multilocularis tumor protein p63 0.1087 0.1181 0.3732
Onchocerca volvulus Neuropeptide F receptor homolog 0.0095 0.0078 0.0476
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0044 0.0021 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Echinococcus granulosus ecdysone induced protein 78C 0.0062 0.0041 0.013
Schistosoma mansoni hypothetical protein 0.0095 0.0078 0.0245
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0044 0.0021 0.0066
Echinococcus multilocularis neuropeptide Y receptor 0.0095 0.0078 0.0245
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.2869 0.3165 1
Entamoeba histolytica cysteine proteinase, putative 0.0066 0.0045 0.4054
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.0101 0.1957
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.0067 0.0047 0.0047
Echinococcus multilocularis fmrfamide receptor 0.0095 0.0078 0.0245
Echinococcus multilocularis g protein coupled receptor 0.0095 0.0078 0.0245
Schistosoma mansoni cpg binding protein 0.0062 0.0041 0.0129
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0059 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0062 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0038 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0004
Echinococcus granulosus FTZ F1 alpha 0.0062 0.0041 0.013
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0062 0.0041 0.0041
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0014 0.0146
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0095 0.0078 0.0245
Brugia malayi Bromodomain containing protein 0.0029 0.0004 0.0004
Echinococcus granulosus fibronectin type III domain-containing protein 0.0033 0.0009 0.0028
Brugia malayi G protein-coupled receptor 0.0095 0.0078 0.0078
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0038 0.0638
Echinococcus multilocularis ecdysone induced protein 78C 0.0062 0.0041 0.013
Loa Loa (eye worm) hypothetical protein 0.0084 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0062 0.0041 0.0041
Loa Loa (eye worm) ctsf protein 0.0116 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Loa Loa (eye worm) peptidase family M13 containing protein 0.2158 0.2374 0.2373
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0711 0.0763 0.2411
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0196 0.0619
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Brugia malayi MH1 domain containing protein 0.0053 0.0031 0.0031
Schistosoma mansoni cpg binding protein 0.0059 0.0037 0.0117
Echinococcus multilocularis neuropeptide s receptor 0.0095 0.0078 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0031 0.0097
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1275 0.1391 0.4395
Brugia malayi Cathepsin L-like precursor 0.0082 0.0063 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0078 0.0245
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0033 0.0009 0.0009
Echinococcus granulosus lamin 0.0084 0.0065 0.0205
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0038 0.0119
Schistosoma mansoni amine GPCR 0.0095 0.0078 0.0245
Schistosoma mansoni hypothetical protein 0.0118 0.0103 0.0326
Brugia malayi nuclear receptor NHR-88 0.0062 0.0041 0.0041
Echinococcus multilocularis lysosomal alpha glucosidase 0.0183 0.0175 0.0553
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0062 0.0041 0.013
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0837 0.0903 0.2854
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0033 0.0009 0.0028
Onchocerca volvulus 0.0116 0.0101 0.062
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0031 0.0568
Echinococcus multilocularis Fibronectin, type III 0.0033 0.0009 0.0028
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0031 0.0085
Schistosoma mansoni polyhomeotic 0.0044 0.0021 0.0066
Echinococcus granulosus neuropeptide receptor 0.0095 0.0078 0.0245
Brugia malayi Smad1 0.0053 0.0031 0.0031
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0032 0.0007 0.0226
Toxoplasma gondii hypothetical protein 0.0084 0.0066 0.0195
Schistosoma mansoni amine GPCR 0.0095 0.0078 0.0245
Echinococcus multilocularis lamin dm0 0.0084 0.0065 0.0205
Brugia malayi nuclear receptor RXR 0.0029 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0078 0.0245
Loa Loa (eye worm) latrophilin receptor protein 2 0.0118 0.0103 0.0103
Onchocerca volvulus 0.0038 0.0014 0.0087
Loa Loa (eye worm) tnks protein 0.0044 0.0021 0.0021
Plasmodium falciparum cysteine repeat modular protein 4 0.0084 0.0066 0.6341
Schistosoma mansoni intermediate filament proteins 0.0084 0.0065 0.0205
Echinococcus granulosus tm gpcr rhodopsin 0.06 0.0639 0.2019
Plasmodium vivax unspecified product 0.0066 0.0045 0.4252
Echinococcus multilocularis anosmin 1 0.0033 0.0009 0.0028
Brugia malayi hypothetical protein 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0029 0.0005 0.0029
Echinococcus granulosus anosmin 1 0.0033 0.0009 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0017 0.0261
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0664 0.071 0.2244
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Schistosoma mansoni cathepsin C 0.0032 0.0007 0.0022
Onchocerca volvulus 0.0059 0.0037 0.0228
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0071 0.0051 0.0159
Brugia malayi ORL1-like opioid receptor 0.0095 0.0078 0.0078
Brugia malayi hypoxia-induced factor 1 0.0166 0.0157 0.0157
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.0044 0.0021 0.0291
Echinococcus multilocularis Netrin receptor DCC 0.0033 0.0009 0.0028
Trypanosoma cruzi cysteine proteinase, putative 0.0066 0.0045 0.0885
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.0078 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.0101 0.1957
Echinococcus multilocularis leukotriene A 4 hydrolase 0.023 0.0228 0.0718
Echinococcus granulosus g protein coupled receptor 0.0095 0.0078 0.0245
Schistosoma mansoni retinoic acid receptor RXR 0.0062 0.0041 0.013
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0033 0.0009 0.0088
Onchocerca volvulus 0.0082 0.0063 0.0387
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Brugia malayi Calcitonin receptor-like protein seb-1 0.0373 0.0388 0.0388
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0041 0.013
Plasmodium falciparum serine repeat antigen 7 0.0032 0.0007 0.0333
Plasmodium falciparum serine repeat antigen 1 0.0032 0.0007 0.0333
Loa Loa (eye worm) hypothetical protein 0.0044 0.0021 0.0021
Trypanosoma cruzi cruzipain precursor, putative 0.0034 0.001 0.0108
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0182 0.0175 0.3729
Echinococcus multilocularis serotonin receptor 0.0095 0.0078 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Loa Loa (eye worm) RNA binding protein 0.0201 0.0196 0.0196
Echinococcus granulosus cathepsin l1 0.0116 0.0101 0.0319
Brugia malayi AKH receptor 0.0095 0.0078 0.0078
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0007 0.0022
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0033 0.0009 0.0028
Schistosoma mansoni hypothetical protein 0.0084 0.0066 0.0207
Echinococcus granulosus sex peptide receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi hypothetical protein 0.0044 0.0021 0.0021
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0017 0.0052
Loa Loa (eye worm) hypothetical protein 0.0082 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0854 0.0922 0.0922
Schistosoma mansoni coup transcription factor 0.0062 0.0041 0.013
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Schistosoma mansoni cathepsin s 0.0034 0.001 0.0031
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0031 0.0097
Schistosoma mansoni alpha-glucosidase 0.0157 0.0147 0.0463
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0116 0.0101 0.0319
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0062 0.0041 0.013
Schistosoma mansoni lamin 0.0084 0.0065 0.0205
Brugia malayi coiled-coil like protein 1 0.0067 0.0047 0.0047
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0373 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0005 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Echinococcus multilocularis cathepsin b 0.0438 0.046 0.1451
Schistosoma mansoni titin 0.0034 0.001 0.003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Echinococcus granulosus cathepsin b 0.0438 0.046 0.1451
Loa Loa (eye worm) steroid hormone receptor 0.0062 0.0041 0.0041
Trypanosoma brucei protein kinase, putative 0.0053 0.0031 0.1071
Onchocerca volvulus 0.0095 0.0078 0.0476
Brugia malayi SPRY domain containing protein 0.0033 0.0009 0.0009
Brugia malayi hypothetical protein 0.0029 0.0005 0.0005
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0033 0.0009 0.0028
Schistosoma mansoni phd finger protein 0.0048 0.0025 0.0078
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0014 0.0146
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0033 0.0009 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0041 0.0041
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0001 0.0002
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0032 0.0007 0.0226
Brugia malayi hypothetical protein 0.0106 0.009 0.009
Echinococcus granulosus peptide allatostatin:somatostatin 0.0095 0.0078 0.0245
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0033 0.0009 0.0009
Brugia malayi AIDA-1b 0.0044 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0036 0.0012 0.0035
Brugia malayi MAP kinase sur-1 0.0053 0.0031 0.0031
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0033 0.0009 0.0028
Brugia malayi GCC2 and GCC3 family protein 0.0084 0.0066 0.0066
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0005 0.0014
Plasmodium falciparum cysteine repeat modular protein 2 0.0084 0.0066 0.6341
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0059 0.0142
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0032 0.0007 0.0333
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Loa Loa (eye worm) hypothetical protein 0.0118 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0301 0.0307 0.0969
Echinococcus multilocularis mothers against decapentaplegic 5 0.0053 0.0031 0.0096
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0157 0.0147 0.0464
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0196 0.0619
Schistosoma mansoni cell adhesion molecule 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Plasmodium vivax vivapain-3 0.0066 0.0045 0.4252
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0059 0.1078
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Schistosoma mansoni cellular tumor antigen P53 0.0159 0.0149 0.047
Schistosoma mansoni neprilysin-2 (M13 family) 0.1374 0.1501 0.4744
Echinococcus multilocularis G-protein coupled receptor, putative 0.0095 0.0078 0.0245
Brugia malayi photoreceptor-specific nuclear receptor 0.0062 0.0041 0.0041
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.1374 0.1501 0.4744
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.001 0.001
Giardia lamblia Giardia trophozoite antigen GTA-1 0.0044 0.0021 0.1206
Mycobacterium leprae probable zinc metalloprotease 0.2869 0.3165 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0014 0.0045
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0005 0.0005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0095 0.0078 0.0078
Schistosoma mansoni biogenic amine receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.006 0.0038 0.0038
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0017 0.0052
Giardia lamblia Encystation-specific protease 0.0032 0.0007 0.0226
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0041 0.013
Schistosoma mansoni opsin-like receptor 0.0095 0.0078 0.0245
Giardia lamblia Cathepsin L precursor 0.0032 0.0007 0.0226
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.2869 0.3165 1
Toxoplasma gondii ABC1 family protein 0.0038 0.0014 0.0033
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Echinococcus granulosus tar DNA binding protein 0.0201 0.0196 0.0619
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Echinococcus multilocularis FTZ F1 alpha 0.0062 0.0041 0.013
Brugia malayi Cathepsin L-like cysteine proteinase 0.0082 0.0063 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0014 0.02
Loa Loa (eye worm) hypothetical protein 0.1495 0.1635 0.1635
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0161 0.0151 0.0434
Giardia lamblia Hypothetical protein 0.0032 0.0007 0.0226
Brugia malayi hypothetical protein 0.0095 0.0078 0.0078
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0031 0.0568
Giardia lamblia Cathepsin B precursor 0.0032 0.0007 0.0226
Plasmodium falciparum serine repeat antigen 5 0.0032 0.0007 0.0333
Loa Loa (eye worm) MH1 domain-containing protein 0.0053 0.0031 0.003
Giardia lamblia Cathepsin B precursor 0.0157 0.0147 1
Echinococcus multilocularis musashi 0.0084 0.0065 0.0205
Brugia malayi Lethal protein 805 0.0033 0.0009 0.0009
Giardia lamblia Cysteine protease 0.0032 0.0007 0.0226
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0095 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.001
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0095 0.0078 0.0078
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0095 0.0078 0.0245
Schistosoma mansoni ephrin receptor 0.0862 0.0932 0.2943
Echinococcus granulosus jumonji domain containing protein 0.004 0.0017 0.0051
Brugia malayi tailless protein 0.0029 0.0005 0.0005
Echinococcus granulosus lysosomal alpha glucosidase 0.0183 0.0175 0.0553
Onchocerca volvulus Cathepsin L homolog 0.0032 0.0007 0.0044
Plasmodium falciparum cysteine proteinase falcipain 1 0.0066 0.0045 0.4252
Loa Loa (eye worm) G-protein coupled receptor 0.0095 0.0078 0.0078
Loa Loa (eye worm) CAMK protein kinase 0.0034 0.001 0.0009
Brugia malayi Serotonin receptor 0.0095 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0116 0.0101 0.0101
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Schistosoma mansoni hypothetical protein 0.0095 0.0078 0.0245
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0017 0.1043
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0032 0.0007 0.0022
Onchocerca volvulus Alhambra homolog 0.0029 0.0004 0.0025
Onchocerca volvulus 0.0033 0.0009 0.0056
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0066 0.0045 0.0143
Schistosoma mansoni cpg binding protein 0.0062 0.0041 0.0129
Schistosoma mansoni hypothetical protein 0.0547 0.058 0.1832
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0017 0.1043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0095 0.0078 0.0245
Schistosoma mansoni nephrin 0.0033 0.0009 0.0028
Schistosoma mansoni RAR-like nuclear receptor 0.0062 0.0041 0.013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.018 0.0172 0.0172
Brugia malayi Glycosyl hydrolases family 31 protein 0.0183 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.031 0.0316 0.0316
Schistosoma mansoni hypothetical protein 0.0118 0.0103 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0038 0.5
Brugia malayi MH2 domain containing protein 0.0773 0.0832 0.0832
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0301 0.0307 0.0307
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0062 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Echinococcus granulosus peregrin 0.0029 0.0004 0.0012
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0017 0.0051
Brugia malayi Cathepsin L-like precursor 0.0082 0.0063 0.0063
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0095 0.0078 0.0245
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0062 0.0041 0.013
Schistosoma mansoni lip-related protein (liprin) alpha 0.0067 0.0047 0.0148
Loa Loa (eye worm) myotactin form A 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0062 0.0041 0.0041
Brugia malayi peptidase family M13 containing protein 0.0664 0.071 0.071
Loa Loa (eye worm) intermediate filament protein 0.0084 0.0065 0.0065
Loa Loa (eye worm) leukotriene A4 hydrolase 0.023 0.0228 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0063 0.1163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Schistosoma mansoni biogenic amine receptor 0.0095 0.0078 0.0245
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0032 0.0007 0.0333
Echinococcus granulosus Fibronectin type III domain containing protein 0.0033 0.0009 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0059 0.0186
Trypanosoma cruzi cysteine protease, putative 0.0066 0.0045 0.0885
Loa Loa (eye worm) TK/EPH protein kinase 0.1034 0.1123 0.1122
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0033 0.0009 0.0028
Brugia malayi hypothetical protein 0.018 0.0172 0.0172
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0031 0.1243
Onchocerca volvulus 0.0116 0.0101 0.062
Loa Loa (eye worm) hypothetical protein 0.0067 0.0047 0.0047
Echinococcus granulosus titin 0.0034 0.001 0.003
Echinococcus multilocularis cathepsin L 0.0066 0.0045 0.0143
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0007 0.0007
Brugia malayi cathepsin B-like cysteine proteinase 0.0438 0.046 0.046
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0033 0.0009 0.0028
Schistosoma mansoni hypothetical protein 0.0029 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0373 0.0388 0.0387
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.06 0.0639 0.2019
Brugia malayi sulfakinin receptor protein 0.031 0.0316 0.0316
Echinococcus multilocularis cathepsin L 0.0032 0.0007 0.0022
Brugia malayi hypothetical protein 0.0033 0.0009 0.0009
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0014 0.0044
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0053 0.0031 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0031 0.0494
Schistosoma mansoni hypothetical protein 0.0711 0.0763 0.2411
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0005 0.0014
Loa Loa (eye worm) MH2 domain-containing protein 0.0053 0.0031 0.003
Echinococcus multilocularis neuropeptide receptor A26 0.0095 0.0078 0.0245
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0005 0.0004
Schistosoma mansoni hypothetical protein 0.0711 0.0763 0.2411
Schistosoma mansoni chromobox protein 0.0189 0.0182 0.0574
Loa Loa (eye worm) hypothetical protein 0.0038 0.0014 0.0014
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0005 0.0005
Echinococcus multilocularis titin 0.0033 0.0009 0.0028
Brugia malayi nuclear receptor RXR 0.0033 0.0009 0.0009
Schistosoma mansoni aldehyde dehydrogenase 0.0209 0.0204 0.0645
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0009 0.0009
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0005 0.0029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0041 0.0041
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0014 0.0014
Schistosoma mansoni neuropeptide receptor 0.0095 0.0078 0.0245
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0209 0.0204 0.0603
Schistosoma mansoni factor for adipocyte differentiation 0.0033 0.0009 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0078 0.0245
Brugia malayi Fibronectin type III domain containing protein 0.0033 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.2158 0.2374 0.2373
Echinococcus multilocularis neutral alpha glucosidase AB 0.0041 0.0017 0.0053
Giardia lamblia Cathepsin L precursor 0.0032 0.0007 0.0226
Echinococcus multilocularis peregrin 0.0029 0.0004 0.0012
Onchocerca volvulus Protein ultraspiracle homolog 0.0062 0.0041 0.0253
Brugia malayi fibroinase precursor 0.0032 0.0007 0.0007
Loa Loa (eye worm) POT family protein 0.026 0.0262 0.0261
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0007 0.0022
Schistosoma mansoni hypothetical protein 0.0711 0.0763 0.2411
Onchocerca volvulus 0.0095 0.0078 0.0476
Mycobacterium ulcerans epoxide hydrolase EphA 0.0161 0.0151 0.0434
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0059 0.1187
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0038 0.0721
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.023 0.0228 0.0718
Brugia malayi MH2 domain containing protein 0.0053 0.0031 0.0031
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0095 0.0078 0.0245
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0042 0.0019 0.0058
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0116 0.0101 1
Echinococcus multilocularis survival motor neuron protein 1 0.0508 0.0537 0.1696
Brugia malayi neuropeptide F receptor 0.0095 0.0078 0.0078
Plasmodium falciparum cysteine repeat modular protein 1 0.0084 0.0066 0.6341
Schistosoma mansoni smad1 5 8 and 0.0053 0.0031 0.0096
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0007 0.0007
Echinococcus multilocularis roundabout 2 0.0033 0.0009 0.0028
Schistosoma mansoni neprilysin 0.0711 0.0763 0.2411
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0038 0.012
Echinococcus granulosus lamin dm0 0.0084 0.0065 0.0205
Plasmodium falciparum cysteine proteinase falcipain 3 0.0116 0.0101 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0034 0.001 0.0009
Echinococcus multilocularis dro:myosuppressin receptor 0.0095 0.0078 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0062 0.0041 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0062 0.0041 0.0041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0038 0.0721
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0034 0.001 0.0009
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0118 0.0103 0.0326
Schistosoma mansoni Nep2 peptidase (M13 family) 0.1374 0.1501 0.4744
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0005 0.0004
Onchocerca volvulus 0.0033 0.0009 0.0056
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0062 0.0041 0.013
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0059 0.1187
Brugia malayi jmjC domain containing protein 0.0038 0.0014 0.0014
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0062 0.0041 0.013
Mycobacterium ulcerans putative regulatory protein 0.004 0.0016 0.0006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0014 0.0014
Schistosoma mansoni amine GPCR 0.0095 0.0078 0.0245
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.9012 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0183 0.0175 0.0175
Onchocerca volvulus 0.0033 0.0009 0.0056
Giardia lamblia Hypothetical protein 0.0032 0.0007 0.0226
Leishmania major cathepsin L-like protease 0.0216 0.0213 1
Onchocerca volvulus 0.0095 0.0078 0.0476
Brugia malayi Shank2E 0.0046 0.0024 0.0024
Echinococcus multilocularis g-protein coupled receptor 0.0095 0.0078 0.0245
Brugia malayi beta-lactamase 0.0038 0.0014 0.0014
Echinococcus granulosus Netrin receptor DCC 0.0033 0.0009 0.0028
Onchocerca volvulus 0.0033 0.0009 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.0101 0.1957
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.2158 0.2374 0.2373
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0078 0.0245
Brugia malayi cathepsin L-like precursor 0.0082 0.0063 0.0063
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0095 0.0078 0.0245
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0062 0.0041 0.013
Onchocerca volvulus 0.0044 0.0021 0.013
Loa Loa (eye worm) hypothetical protein 0.2206 0.2426 0.2426
Brugia malayi Cathepsin L-like precursor 0.0116 0.0101 0.0101
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 24 0.0044 0.0021 0.0593
Echinococcus multilocularis liprin alpha 2 0.0044 0.0021 0.0066
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0095 0.0078 0.0245
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0098 0.0298
Echinococcus multilocularis Sterile alpha motif SAM 0.0044 0.0021 0.0066
Onchocerca volvulus 0.0095 0.0078 0.0476
Loa Loa (eye worm) hypothetical protein 0.0062 0.0041 0.0041
Loa Loa (eye worm) AIDA-1b 0.0044 0.0021 0.0021
Echinococcus multilocularis fibronectin type III domain-containing protein 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0044 0.0021 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0033 0.0009 0.0028
Echinococcus multilocularis usherin 0.0033 0.0009 0.0028
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0041 0.013
Schistosoma mansoni factor for adipocyte differentiation 0.0033 0.0009 0.0028
Leishmania major cathepsin L-like protease 0.0116 0.0101 0.4634
Echinococcus multilocularis dnaJ subfamily B 0.0837 0.0903 0.2854
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0095 0.0078 0.0476
Giardia lamblia CEGP1 protein 0.0084 0.0066 0.4314
Plasmodium falciparum serine repeat antigen 9 0.0032 0.0007 0.0333
Schistosoma mansoni ap endonuclease 0.0059 0.0038 0.0119
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0095 0.0078 0.0476
Echinococcus multilocularis sex peptide receptor 0.0095 0.0078 0.0245
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.006 0.1209
Loa Loa (eye worm) hypothetical protein 0.2158 0.2374 0.2373
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.2869 0.3165 0.3164
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Schistosoma mansoni ephrin receptor 0.0042 0.0019 0.0058
Loa Loa (eye worm) hypothetical protein 0.2158 0.2374 0.2373
Brugia malayi myotactin form B 0.0033 0.0009 0.0009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0301 0.0307 0.0969
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0007
Echinococcus granulosus dro:myosuppressin receptor 0.0095 0.0078 0.0245
Brugia malayi hypothetical protein 0.0044 0.0021 0.0021
Onchocerca volvulus Cathepsin L homolog 0.0116 0.0101 0.062
Mycobacterium tuberculosis Possible exported protein 0.2542 0.2801 0.8846
Brugia malayi Cathepsin L-like precursor 0.0116 0.0101 0.0101
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) peptidase family M13 containing protein 0.2158 0.2374 0.2373
Echinococcus granulosus TGF beta signal transducer SmadC 0.0053 0.0031 0.0096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0062 0.0041 0.0041
Echinococcus granulosus leukotriene A 4 hydrolase 0.023 0.0228 0.0718
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0041 0.0041
Echinococcus granulosus cathepsin L cysteine proteinase 0.0116 0.0101 0.0319
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0017 0.0261
Loa Loa (eye worm) hypothetical protein 0.0044 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Loa Loa (eye worm) beta-lactamase 0.0038 0.0014 0.0014
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.0067 0.0047 0.0047
Echinococcus multilocularis polycomb protein SCMH1 0.0044 0.0021 0.0066
Echinococcus multilocularis cathepsin L cysteine protease 0.0116 0.0101 0.0319
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0059 0.1078
Schistosoma mansoni nuclear receptor 0.0029 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0062 0.0041 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0216 0.0213 1
Trypanosoma brucei glucosidase, putative 0.0041 0.0017 0.0386
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Toxoplasma gondii GCC2 and GCC3 domain-containing protein 0.0084 0.0066 0.0195
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0005 0.0014
Plasmodium vivax cysteine repeat modular protein 3, putative 0.0084 0.0066 0.6341
Plasmodium vivax unspecified product 0.0032 0.0007 0.0333
Entamoeba histolytica cysteine proteinase 2 0.0066 0.0045 0.4054
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0664 0.071 0.2244
Echinococcus multilocularis neuropeptide receptor 0.0198 0.0193 0.0608
Onchocerca volvulus 0.0095 0.0078 0.0476
Onchocerca volvulus 0.0033 0.0009 0.0056
Giardia lamblia Kinesin-13 0.0044 0.0021 0.1206
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0078 0.0245
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0009 0.0008
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0031 0.0568
Trichomonas vaginalis set domain proteins, putative 0.0464 0.0488 1
Giardia lamblia Cathepsin L precursor 0.0032 0.0007 0.0226
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0037 0.0037
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0033 0.0009 0.0028
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0084 0.0065 0.0065
Brugia malayi Fibronectin type III domain containing protein 0.0033 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0005 0.0014
Trypanosoma cruzi cysteine peptidase, putative 0.0216 0.0213 0.4569
Brugia malayi hypothetical protein 0.0095 0.0078 0.0078
Giardia lamblia Cathepsin L precursor 0.0032 0.0007 0.0226
Echinococcus granulosus neuropeptides capa receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0408 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Schistosoma mansoni cathepsin F (C01 family) 0.0116 0.0101 0.0319
Echinococcus granulosus single minded 2 0.004 0.0016 0.005
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi intermediate filament protein 0.0084 0.0065 0.0065
Echinococcus granulosus biogenic amine 5HT receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0038 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0033 0.0009 0.0056
Echinococcus granulosus sterile alpha and tir motif containing protein 0.0067 0.0047 0.0148
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0008
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0033 0.0009 0.0028
Schistosoma mansoni aldehyde dehydrogenase 0.0209 0.0204 0.0645
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0034 0.0108
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0009 0.0026
Brugia malayi latrophilin 2 splice variant baaae 0.0255 0.0256 0.0256
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0005 0.0005
Echinococcus multilocularis neuropeptide receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) transcription factor SMAD2 0.0773 0.0832 0.0832
Echinococcus granulosus alpha 1A adrenergic receptor 0.0095 0.0078 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.0101 0.1957
Onchocerca volvulus 0.0034 0.001 0.006
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0062 0.0041 0.013
Schistosoma mansoni biogenic amine receptor 0.0095 0.0078 0.0245
Brugia malayi cathepsin L-like cysteine proteinase 0.0032 0.0007 0.0007
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0033 0.0009 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0116 0.0101 0.1957
Schistosoma mansoni histamine h1 receptor 0.0095 0.0078 0.0245
Schistosoma mansoni hypothetical protein 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi PHD-finger family protein 0.0029 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0008
Brugia malayi cathepsin L precursor 0.0032 0.0007 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0078 0.0245
Brugia malayi beta-lactamase family protein 0.0038 0.0014 0.0014
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0032 0.0007 0.0333
Plasmodium vivax tyrosine kinase-like protein, putative 0.0032 0.0007 0.0308
Brugia malayi G-protein coupled receptor 0.0095 0.0078 0.0078
Giardia lamblia Cysteine protease 0.0032 0.0007 0.0226
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0033 0.0009 0.0009
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0113 0.0356
Giardia lamblia Cathepsin L-like protease 0.0032 0.0007 0.0226
Plasmodium falciparum tyrosine kinase-like protein 0.0032 0.0007 0.0308
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0041 0.013
Echinococcus granulosus cathepsin L cysteine protease 0.0066 0.0045 0.0143
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0066 0.0045 0.0143
Schistosoma mansoni adenoreceptor 0.0095 0.0078 0.0245
Schistosoma mansoni hypothetical protein 0.0547 0.058 0.1832
Entamoeba histolytica cysteine protease, putative 0.0116 0.0101 1
Echinococcus multilocularis transfer RNA-Phe 0.0033 0.0009 0.0028
Onchocerca volvulus 0.0044 0.0021 0.013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0438 0.046 0.1451
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0095 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0033 0.0009 0.0028
Echinococcus granulosus neuropeptide FF receptor 2 0.0095 0.0078 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0157 0.0147 0.2908
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0059 0.0186
Echinococcus granulosus Sterile alpha motif SAM 0.0067 0.0047 0.0148
Echinococcus granulosus nephrin 0.0033 0.0009 0.0028
Schistosoma mansoni hypothetical protein 0.0118 0.0103 0.0326
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Giardia lamblia Cathepsin L precursor 0.0032 0.0007 0.0226
Brugia malayi MH1 domain containing protein 0.0029 0.0004 0.0004
Echinococcus granulosus polyhomeotic protein 2 0.0044 0.0021 0.0066
Onchocerca volvulus 0.0116 0.0101 0.062
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Onchocerca volvulus 0.0084 0.0066 0.0402
Giardia lamblia Cathepsin B precursor 0.0032 0.0007 0.0226
Brugia malayi cathepsin Z-like cysteine proteinase 0.0032 0.0007 0.0007
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0095 0.0078 0.0245
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0031 0.0494
Entamoeba histolytica cysteine proteinase, putative 0.0066 0.0045 0.4054
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.0078 0.0245
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.005 0.0113
Echinococcus granulosus histone acetyltransferase myst3 0.0048 0.0025 0.0078
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0031 0.0494
Schistosoma mansoni cathepsin S (C01 family) 0.0032 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Echinococcus granulosus cathepsin b 0.0438 0.046 0.1451
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0038 0.1413
Toxoplasma gondii cathepsin B 0.0157 0.0147 0.0453
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0032 0.0007 0.0226
Onchocerca volvulus 0.004 0.0016 0.0099
Brugia malayi Dopamine receptor protein 2 0.0095 0.0078 0.0078
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0014 0.0045
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0031 0.0097
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Brugia malayi nuclear hormone receptor 0.0029 0.0005 0.0005
Schistosoma mansoni opsin-like receptor 0.0095 0.0078 0.0245
Echinococcus granulosus cathepsin L 0.0032 0.0007 0.0022
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0009 0.0009
Echinococcus granulosus contactin 0.0033 0.0009 0.0028
Echinococcus granulosus Fibronectin type III 0.0033 0.0009 0.0028
Entamoeba histolytica cysteine proteinase 1, putative 0.0066 0.0045 0.4054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.0101 0.1957
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0664 0.071 0.2244
Brugia malayi Pre-SET motif family protein 0.006 0.0038 0.0038
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0031 0.0568
Brugia malayi hypothetical protein 0.0033 0.0009 0.0009
Schistosoma mansoni DNAj-like protein 0.0044 0.0021 0.0066
Echinococcus granulosus roundabout 2 0.0033 0.0009 0.0028
Brugia malayi G-protein coupled receptor 0.0095 0.0078 0.0078
Echinococcus granulosus tachykinin peptides receptor 99D 0.0095 0.0078 0.0245
Echinococcus granulosus polycomb protein SCMH1 0.0044 0.0021 0.0066
Schistosoma mansoni nuclear receptor 0.0029 0.0005 0.0014
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Schistosoma mansoni lar interacting protein (lip)-related protein 0.0067 0.0047 0.0148
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Schistosoma mansoni myosin-binding protein-related 0.0033 0.0009 0.0028
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0041 0.013
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0095 0.0078 0.0245
Schistosoma mansoni sex comb on midleg homolog 0.0044 0.0021 0.0066
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0004 0.0012
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0032 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0038 0.3486
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0038 0.3486
Plasmodium vivax unspecified product 0.0034 0.001 0.0627
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0017 0.0204
Echinococcus granulosus smad 0.0053 0.0031 0.0096
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0004
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0038 0.0075
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0038 0.0108
Toxoplasma gondii cathepsin CPC1 0.0032 0.0007 0.001
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.001 0.0108
Giardia lamblia Cathepsin B precursor 0.0157 0.0147 1
Giardia lamblia Cathepsin B precursor 0.0032 0.0007 0.0226
Schistosoma mansoni Protein aveugle 0.0044 0.0021 0.0066
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0032 0.0007 0.0007
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0033 0.0009 0.0028
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0095 0.0078 0.0245
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0014 0.0146
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0118 0.0103 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0017 0.0204
Echinococcus granulosus chromobox protein 2 0.0189 0.0182 0.0574
Loa Loa (eye worm) hypothetical protein 0.0062 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0021 0.0291
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0095 0.0078 0.0245
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Giardia lamblia Cathepsin L precursor 0.0032 0.0007 0.0226
Entamoeba histolytica cysteine-rich surface protein, putative 0.0084 0.0066 0.6215
Onchocerca volvulus 0.0095 0.0078 0.0476
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0032 0.0007 0.0333
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0005 0.0014
Echinococcus granulosus 7tm_1 domain containing protein 0.0095 0.0078 0.0245
Plasmodium falciparum serine repeat antigen 6 0.0032 0.0007 0.0333
Trypanosoma cruzi Kinesin-13 5, putative 0.0044 0.0021 0.0354
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0116 0.0101 0.0101
Onchocerca volvulus 0.0116 0.0101 0.062
Echinococcus multilocularis cysteine protease 0.0116 0.0101 0.0319
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0031 0.0494
Schistosoma mansoni factor for adipocyte differentiation 0.0033 0.0009 0.0028
Echinococcus granulosus mothers against decapentaplegic 5 0.0053 0.0031 0.0096
Loa Loa (eye worm) cysteine protease 0.0116 0.0101 0.0101
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0011 0.0033
Brugia malayi Melatonin receptor type 1A 0.0095 0.0078 0.0078
Brugia malayi GnHR receptor homolog 0.0542 0.0575 0.0575
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0059 0.1078
Echinococcus multilocularis ephrin type A receptor 4 A 0.0947 0.1025 0.3239
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0032 0.0007 0.0333
Plasmodium vivax SET domain protein, putative 0.006 0.0038 0.352
Giardia lamblia Hypothetical protein 0.0084 0.0066 0.4314
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0116 0.0101 0.062
Giardia lamblia Cathepsin B precursor 0.0032 0.0007 0.0226
Echinococcus granulosus g-protein coupled receptor 0.0095 0.0078 0.0245
Onchocerca volvulus Tankyrase homolog 0.0044 0.0021 0.013
Echinococcus granulosus orexin receptor type 2 0.0095 0.0078 0.0245
Brugia malayi hypothetical protein 0.031 0.0316 0.0316
Echinococcus multilocularis g protein coupled receptor 0.0095 0.0078 0.0245
Onchocerca volvulus 0.0044 0.0021 0.013
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0035 0.0011 0.0035
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0196 0.0619
Loa Loa (eye worm) Smad1 0.0053 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0255 0.0256 0.0256
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0095 0.0078 0.0078
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0095 0.0078 0.0245
Trypanosoma cruzi major cysteine proteinase, putative 0.0032 0.0007 0.0045
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0301 0.0307 0.0969
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0009
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0032 0.0007 0.0044
Loa Loa (eye worm) hypothetical protein 0.0084 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0067 0.0047 0.0047
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0035 0.0011 0.0035
Echinococcus granulosus neutral alpha glucosidase AB 0.0041 0.0017 0.0053
Brugia malayi hypothetical protein 0.0508 0.0537 0.0537
Entamoeba histolytica cysteine proteinase, putative 0.0066 0.0045 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0045 0.1779
Echinococcus granulosus intermediate filament protein 0.0084 0.0065 0.0205
Schistosoma mansoni lamin 0.0084 0.0065 0.0205
Onchocerca volvulus Cathepsin L homolog 0.0116 0.0101 0.062
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0664 0.071 0.2244
Trichomonas vaginalis cgi-62, putative 0.0044 0.0021 0.0291
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.006 0.5762
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0095 0.0078 0.0245
Schistosoma mansoni cell adhesion molecule 0.0033 0.0009 0.0028
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Loa Loa (eye worm) hypothetical protein 0.2206 0.2426 0.2426
Loa Loa (eye worm) hypothetical protein 0.0082 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0209 0.0204 0.9596
Brugia malayi myotactin form A 0.0033 0.0009 0.0009
Loa Loa (eye worm) UNCoordinated family member 0.0033 0.0009 0.0009
Toxoplasma gondii peptidase family M13 protein 0.2869 0.3165 1
Echinococcus multilocularis neuropeptides capa receptor 0.0095 0.0078 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.0101 0.1957
Brugia malayi follicle stimulating hormone receptor 0.0095 0.0078 0.0078
Loa Loa (eye worm) melatonin receptor type 1A 0.0095 0.0078 0.0078
Onchocerca volvulus 0.0095 0.0078 0.0476
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0041 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0095 0.0078 0.0078
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0004 0.0012
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0031 0.1886
Brugia malayi Cathepsin L-like precursor 0.0116 0.0101 0.0101
Leishmania major cathepsin L-like protease 0.0116 0.0101 0.4634
Onchocerca volvulus 0.0095 0.0078 0.0476
Echinococcus granulosus titin 0.0034 0.001 0.003
Schistosoma mansoni hypothetical protein 0.0044 0.0021 0.0066
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0038 0.2372
Schistosoma mansoni myosin xvIII 0.0095 0.0078 0.0245
Echinococcus granulosus sphingomyelin synthase protein 1 0.0044 0.0021 0.0066
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0004
Echinococcus multilocularis cpg binding protein 0.0062 0.0041 0.0129
Echinococcus multilocularis neuropeptide Y receptor 0.0095 0.0078 0.0245
Brugia malayi MH1 domain containing protein 0.0053 0.0031 0.0031
Echinococcus granulosus G protein coupled receptor 139 0.0095 0.0078 0.0245
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0066 0.0045 0.4054
Schistosoma mansoni zinc finger protein 0.0029 0.0005 0.0014
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0095 0.0078 0.0245
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0014 0.0146
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0032 0.0007 0.0226
Brugia malayi jmjC domain containing protein 0.0094 0.0077 0.0077
Brugia malayi Cathepsin L-like precursor 0.0116 0.0101 0.0101
Brugia malayi nuclear hormone receptor 0.0062 0.0041 0.0041
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0301 0.0307 0.0307

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) = 0.35 uM Cytotoxicity against human HeLa cells after 72 hrs by MTT assay ChEMBL. 20538462
GI50 (functional) = 0.48 uM Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay ChEMBL. 20538462
GI50 (functional) = 0.62 uM Cytotoxicity against human SiHa cells after 72 hrs by MTT assay ChEMBL. 20538462
GI50 (functional) = 1.07 uM Cytotoxicity against human DLD1 cells after 72 hrs by MTT assay ChEMBL. 20538462

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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