Detailed information for compound 143572

Basic information

Technical information
  • TDR Targets ID: 143572
  • Name: (3Z)-3-[(5-ethylthiophen-2-yl)methylidene]-1H -indol-2-one
  • MW: 255.335 | Formula: C15H13NOS
  • H donors: 1 H acceptors: 1 LogP: 3.45 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(s1)/C=C/1\C(=O)Nc2c1cccc2
  • InChi: 1S/C15H13NOS/c1-2-10-7-8-11(18-10)9-13-12-5-3-4-6-14(12)16-15(13)17/h3-9H,2H2,1H3,(H,16,17)/b13-9-
  • InChiKey: MFRZHGSWQHNIEA-LCYFTJDESA-N  


Substructure search Similarity search

Network

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Synonyms

  • (3Z)-3-[(5-ethyl-2-thienyl)methylene]indolin-2-one
  • (3Z)-3-[(5-ethyl-2-thienyl)methylene]-2-indolinone
  • (3Z)-3-[(5-ethyl-2-thienyl)methylene]oxindole

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus FMS-like tyrosine kinase 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) TK/KIN16 protein kinase Get druggable targets OG5_130320 All targets in OG5_130320
Onchocerca volvulus Get druggable targets OG5_130320 All targets in OG5_130320
Brugia malayi Immunoglobulin I-set domain containing protein Get druggable targets OG5_130320 All targets in OG5_130320
Onchocerca volvulus Tyrosine kinase homolog Get druggable targets OG5_130320 All targets in OG5_130320
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax serine-repeat antigen (SERA) 0.0203 0.049 0.096
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.0505 0.0976
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Trypanosoma cruzi cysteine peptidase, putative 0.0864 0.2265 0.4379
Brugia malayi ORL1-like opioid receptor 0.0033 0.0034 0.0065
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0209 0.0505 0.1602
Leishmania major calmodulin-like protein 0.0115 0.0252 0.08
Leishmania major hypothetical protein, conserved 0.0115 0.0252 0.08
Echinococcus multilocularis calpain 7 (C02 family) 0.0801 0.2096 0.3332
Onchocerca volvulus Cathepsin L homolog 0.0864 0.2265 0.8513
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0144 0.0331 0.0527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0864 0.2265 1
Echinococcus granulosus calcyphosin protein 0.0027 0.0018 0.0028
Echinococcus multilocularis programmed cell death protein 0.0142 0.0326 0.0517
Leishmania major hypothetical protein, conserved 0.0209 0.0505 0.1602
Loa Loa (eye worm) hypothetical protein 0.0036 0.0042 0.0067
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0209 0.0505 0.0976
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0203 0.049 0.2165
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0034 0.0053
Echinococcus granulosus flap endonuclease 1 0.0028 0.0021 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0263 0.1163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.049 0.2165
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0801 0.2096 0.6651
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0033 0.0034 0.0053
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.007 0.0132 0.0255
Brugia malayi intermediate filament protein 0.0083 0.0168 0.0324
Schistosoma mansoni neuronal calcium sensor 0.0115 0.0252 0.0252
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Trypanosoma brucei centrin-3 0.0142 0.0326 0.1033
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0764 0.1477
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0115 0.0223
Plasmodium vivax glutathione reductase, putative 0.0202 0.0487 0.0953
Schistosoma mansoni tar DNA-binding protein 0.0062 0.011 0.011
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0864 0.2265 0.36
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0742 0.1938 0.615
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Entamoeba histolytica prefoldin subunit 6, putative 0.0062 0.011 0.0484
Onchocerca volvulus Cathepsin L homolog 0.0203 0.049 0.1791
Entamoeba histolytica cysteine proteinase, putative 0.0596 0.1545 0.6824
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0033 0.0034 0.0034
Trichomonas vaginalis calmodulin-2, putative 0.0115 0.0252 0.1113
Brugia malayi Cytochrome P450 family protein 0.0032 0.0031 0.0059
Loa Loa (eye worm) leukotriene A4 hydrolase 0.2363 0.6292 1
Entamoeba histolytica calcium-binding protein, putative 0.0115 0.0252 0.1113
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Schistosoma mansoni reticulocalbin 0.0115 0.0252 0.0252
Echinococcus multilocularis cpg binding protein 0.0031 0.0026 0.0041
Leishmania major centrin, putative 0.0115 0.0252 0.08
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0021 0.004
Brugia malayi calpain D 0.0334 0.0842 0.1629
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0117 0.0259 0.0501
Trichomonas vaginalis calcium binding protein, putative 0.0115 0.0252 0.1113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Onchocerca volvulus 0.0485 0.1247 0.4657
Brugia malayi POT family protein 0.0045 0.0064 0.0124
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0066 0.0129
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0105
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0115 0.0183
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0034 0.0036 0.0057
Schistosoma mansoni ef hand domain family member A2 0.0115 0.0252 0.0252
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0118 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0338 0.0853 0.3766
Echinococcus granulosus cathepsin l1 0.0864 0.2265 0.36
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0042 0.0319
Echinococcus granulosus calpain A 0.1928 0.5125 0.8145
Schistosoma mansoni cathepsin B (C01 family) 0.0203 0.049 0.049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.049 0.2165
Entamoeba histolytica cysteine protease, putative 0.0203 0.049 0.2165
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0033 0.0034 0.0053
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0038 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0203 0.049 0.2165
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.015 0.0348 0.0554
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0742 0.1938 0.1938
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.007 0.0132 0.0132
Schistosoma mansoni myosin regulatory light chain 0.0027 0.0018 0.0018
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0156 0.0306
Brugia malayi Neuronal calcium sensor family protein 1 0.0027 0.0018 0.0034
Leishmania major i/6 autoantigen-like protein 0.0115 0.0252 0.08
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0039 0.0062
Loa Loa (eye worm) hypothetical protein 0.023 0.0562 0.0893
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0203 0.049 0.096
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Schistosoma mansoni calpain-7 (C02 family) 0.0801 0.2096 0.2096
Brugia malayi Probable myosin regulatory light chain 0.003 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0596 0.1545 0.2456
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0322 0.0512
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.0196 0.0312
Brugia malayi calpain 5 0.0467 0.1198 0.2316
Trichomonas vaginalis myosin light chain 1, putative 0.0115 0.0252 0.1113
Onchocerca volvulus 0.0033 0.0034 0.0061
Plasmodium vivax vivapain-1 0.0471 0.121 0.2368
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0196 0.0385
Schistosoma mansoni thyroid hormone receptor 0.0138 0.0314 0.0314
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.0505 0.0976
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0209 0.0505 0.1602
Entamoeba histolytica cysteine proteinase 1, putative 0.0471 0.121 0.5341
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0203 0.049 0.096
Echinococcus granulosus orexin receptor type 2 0.0033 0.0034 0.0053
Giardia lamblia Cathepsin B precursor 0.0203 0.049 0.253
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0051 0.0082 0.0159
Trypanosoma brucei hypothetical protein, conserved 0.0115 0.0252 0.08
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0034 0.0034
Brugia malayi Cathepsin L-like precursor 0.0864 0.2265 0.4379
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0428 0.1095 0.174
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0034 0.0053
Giardia lamblia Cysteine protease 0.0203 0.049 0.253
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0305 0.0764 0.2423
Schistosoma mansoni hypothetical protein 0.003 0.0025 0.0025
Leishmania major calmodulin, putative 0.0115 0.0252 0.08
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.0562 0.0893
Schistosoma mansoni calpain-2 (C02 family) 0.0334 0.0842 0.0842
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0196 0.0196
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.047 0.1207 0.3829
Onchocerca volvulus Matrix metalloproteinase homolog 0.0092 0.0191 0.0656
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.007 0.0132 0.0258
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.003 0.0059
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0061
Onchocerca volvulus 0.0115 0.0252 0.0888
Echinococcus granulosus somatostatin receptor 0.0033 0.0034 0.0053
Brugia malayi calcium-binding protein 0.0115 0.0252 0.0487
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0066 0.0105
Loa Loa (eye worm) myosin regulatory light chain 1 0.0027 0.0018 0.0028
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0263 0.1163
Plasmodium falciparum plasmepsin II 0.0144 0.0331 0.0649
Loa Loa (eye worm) hypothetical protein 0.0079 0.0156 0.0249
Echinococcus granulosus Myosin regulatory light chain 0.0027 0.0018 0.0028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0525 0.1355 0.262
Loa Loa (eye worm) hypothetical protein 0.0036 0.0042 0.0067
Brugia malayi Papain family cysteine protease containing protein 0.0471 0.121 0.2339
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0491 0.1262 0.9547
Trypanosoma cruzi centrin, putative 0.0142 0.0326 0.0629
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.007 0.0132 0.0419
Onchocerca volvulus 0.0064 0.0115 0.037
Schistosoma mansoni cathepsin D (A01 family) 0.0425 0.1086 0.1086
Schistosoma mansoni cathepsin s 0.0268 0.0663 0.0663
Leishmania major DNA polymerase eta, putative 0.0032 0.003 0.0094
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0097 0.0097
Plasmodium falciparum serine repeat antigen 3 0.0203 0.049 0.096
Brugia malayi fibroinase precursor 0.0203 0.049 0.0948
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trypanosoma brucei calpain, putative 0.0334 0.0842 0.2673
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0156 0.0306
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0263 0.0509
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0033 0.0034 0.0034
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0203 0.049 0.096
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Echinococcus multilocularis Myosin regulatory light chain 0.0027 0.0018 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0203 0.049 0.2165
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0066 0.0105
Loa Loa (eye worm) intermediate filament protein 0.0083 0.0168 0.0267
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0082 0.0158
Onchocerca volvulus 0.0864 0.2265 0.8513
Schistosoma mansoni calmodulin 0.0115 0.0252 0.0252
Entamoeba histolytica hypothetical protein 0.0039 0.005 0.022
Schistosoma mansoni opsin-like receptor 0.0033 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0094 0.0196 0.0312
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0543 0.1403 0.2713
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Onchocerca volvulus 0.0033 0.0034 0.0061
Loa Loa (eye worm) calpain D 0.0334 0.0842 0.1339
Leishmania major cysteine peptidase A (CPA) 0.0864 0.2265 0.7186
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0026 0.0051
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0203 0.049 0.253
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Trichomonas vaginalis caltractin, putative 0.0027 0.0018 0.0077
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.047 0.1207 0.2333
Echinococcus granulosus centrin 2 0.0115 0.0252 0.0401
Brugia malayi Calmodulin-like protein 0.0115 0.0252 0.0487
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Onchocerca volvulus 0.0057 0.0097 0.03
Toxoplasma gondii microneme protein MIC17A 0.0045 0.0066 0.0129
Mycobacterium tuberculosis Probable dehydrogenase 0.0461 0.1182 0.8954
Entamoeba histolytica cysteine proteinase, putative 0.0471 0.121 0.5341
Echinococcus multilocularis centrin 2 0.0115 0.0252 0.0401
Leishmania major hypothetical protein, conserved 0.0036 0.0042 0.0133
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0042 0.0067
Loa Loa (eye worm) hypothetical protein 0.0336 0.0847 0.1346
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0077 0.015 0.015
Brugia malayi Cytochrome P450 family protein 0.0031 0.0028 0.0054
Echinococcus granulosus EF HAND 1 calcium binding site 0.0115 0.0252 0.0401
Loa Loa (eye worm) hypothetical protein 0.004 0.0052 0.0083
Echinococcus multilocularis netrin receptor unc 5 0.0039 0.005 0.0079
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0034 0.0053
Onchocerca volvulus Cathepsin L homolog 0.0864 0.2265 0.8513
Echinococcus multilocularis calmodulin 0.0115 0.0252 0.0401
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.007 0.0132 0.0255
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0203 0.049 0.049
Trypanosoma brucei calpain-like protein, putative 0.0801 0.2096 0.6651
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0033 0.0034 0.0065
Leishmania major hypothetical protein, conserved 0.0209 0.0505 0.1602
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0336 0.0847 0.1346
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0385 0.0978 0.1891
Giardia lamblia Cathepsin B precursor 0.0742 0.1938 1
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0491 0.1262 1
Onchocerca volvulus 0.0033 0.0034 0.0061
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0137 0.0604
Trichomonas vaginalis calpain, putative 0.0334 0.0842 0.3719
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0066 0.0129
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0263 1
Onchocerca volvulus Netrin receptor homolog 0.0037 0.0045 0.0103
Trichomonas vaginalis centrin, putative 0.0115 0.0252 0.1113
Onchocerca volvulus 0.0045 0.0066 0.0183
Brugia malayi hypothetical protein 0.0257 0.0633 0.1224
Echinococcus granulosus calbindin 32 0.0117 0.0259 0.0412
Brugia malayi Serotonin receptor 0.0033 0.0034 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.011 0.0484
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0864 0.2265 0.36
Schistosoma mansoni hypothetical protein 0.0035 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0864 0.2265 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0268 0.0663 0.1054
Brugia malayi Protein kinase domain containing protein 0.0123 0.0274 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0203 0.049 0.2165
Plasmodium falciparum serine repeat antigen 2 0.0203 0.049 0.096
Mycobacterium ulcerans beta-lactamase 0.0036 0.0042 0.0333
Echinococcus multilocularis transmembrane protease serine 3 0.0057 0.0097 0.0154
Loa Loa (eye worm) hypothetical protein 0.0031 0.0026 0.0041
Echinococcus multilocularis cysteine protease 0.0864 0.2265 0.36
Plasmodium falciparum plasmepsin IV 0.0144 0.0331 0.0649
Onchocerca volvulus 0.0047 0.007 0.0199
Schistosoma mansoni mitochondrial solute carrier 0.0115 0.0252 0.0252
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0077 0.015 0.029
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0034 0.0034
Brugia malayi cathepsin L-like precursor 0.0596 0.1545 0.2988
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0077 0.015 0.0476
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0066 0.0104
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0036 0.0036
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.1922 0.5108 1
Onchocerca volvulus 0.0033 0.0034 0.0061
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0042 0.0319
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0009 0.004
Brugia malayi hypothetical protein 0.0146 0.0336 0.065
Schistosoma mansoni hypothetical protein 0.0128 0.0287 0.0287
Brugia malayi Uncoordinated protein 44 0.003 0.0025 0.0049
Brugia malayi Pre-SET motif family protein 0.0094 0.0196 0.038
Echinococcus granulosus lamin 0.0083 0.0168 0.0267
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.2363 0.6292 0.6292
Brugia malayi hypothetical protein 0.0079 0.0156 0.0302
Brugia malayi G protein-coupled receptor 0.0033 0.0034 0.0065
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0021 0.0091
Loa Loa (eye worm) hypothetical protein 0.0082 0.0164 0.026
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0054 0.009 0.0143
Trypanosoma brucei calpain, putative 0.0599 0.1553 0.4929
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0203 0.049 0.2165
Echinococcus multilocularis serotonin receptor 0.0033 0.0034 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0042 0.0081
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0525 0.1355 0.4299
Loa Loa (eye worm) hypothetical protein 0.0864 0.2265 0.36
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0263 0.2088
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0336 0.0847 0.1637
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0034 0.0034
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0034 0.0053
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0033 0.0034 0.0034
Leishmania major calpain family cysteine protease-like protein 0.0543 0.1403 0.4452
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.005 0.005
Brugia malayi Cathepsin L-like cysteine proteinase 0.0596 0.1545 0.2988
Brugia malayi follicle stimulating hormone receptor 0.0033 0.0034 0.0065
Brugia malayi Animal haem peroxidase family protein 0.0071 0.0135 0.026
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0033 0.0034 0.0061
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0841 0.2205 0.6996
Brugia malayi Cathepsin L-like precursor 0.0864 0.2265 0.4379
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0034 0.0053
Echinococcus granulosus cathepsin b 0.1946 0.5172 0.822
Loa Loa (eye worm) hypothetical protein 0.1811 0.4809 0.7644
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0209 0.0505 0.1602
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.007 0.0132 0.0255
Trichomonas vaginalis calmodulin, putative 0.0115 0.0252 0.1113
Echinococcus granulosus cathepsin l cysteine peptidase 0.0864 0.2265 0.36
Schistosoma mansoni hypothetical protein 0.012 0.0267 0.0267
Leishmania major acetoin dehydrogenase e3 component-like protein 0.007 0.0132 0.0419
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0512 0.132 1
Echinococcus granulosus death domain containing protein 0.003 0.0025 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Toxoplasma gondii kringle domain-containing protein 0.012 0.0267 0.0523
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0864 0.2265 1
Trypanosoma brucei hypothetical protein 0.0599 0.1553 0.4929
Onchocerca volvulus Neuropeptide F receptor homolog 0.0033 0.0034 0.0061
Onchocerca volvulus 0.0336 0.0847 0.3142
Trypanosoma brucei Aminopeptidase M1, putative 0.0485 0.1247 0.3956
Echinococcus multilocularis chromobox protein 1 0.0072 0.0137 0.0217
Leishmania major phospholipase c-like protein 0.0115 0.0252 0.08
Loa Loa (eye worm) calpain 5 0.0467 0.1198 0.1904
Toxoplasma gondii leucyl aminopeptidase LAP 0.0491 0.1262 0.2471
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0203 0.049 0.049
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0485 0.1247 0.1982
Brugia malayi CXXC zinc finger family protein 0.0029 0.0022 0.0042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0992 0.2609 0.5044
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.002 0.009
Trypanosoma cruzi kinesin, putative 0.0467 0.1198 0.2316
Toxoplasma gondii ABC1 family protein 0.0036 0.0042 0.0082
Echinococcus granulosus inhibitor of apoptosis protein 0.0081 0.0162 0.0258
Giardia lamblia Hypothetical protein 0.0203 0.049 0.253
Toxoplasma gondii centrin 0.0115 0.0252 0.0493
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0336 0.0847 0.2687
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0066 0.029
Trichomonas vaginalis calcium binding protein, putative 0.0027 0.0018 0.0077
Onchocerca volvulus Cell death protein 3 homolog 0.0062 0.011 0.035
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1066 0.2807 0.5428
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.003 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0322 0.0512
Brugia malayi Papain family cysteine protease containing protein 0.0864 0.2265 0.4379
Echinococcus multilocularis aminopeptidase N 0.0944 0.2479 0.394
Mycobacterium tuberculosis Probable oxidoreductase 0.0512 0.132 1
Loa Loa (eye worm) EF hand family protein 0.0115 0.0252 0.0401
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0263 0.0836
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0115 0.0183
Loa Loa (eye worm) hypothetical protein 0.0041 0.0055 0.0088
Loa Loa (eye worm) hypothetical protein 0.101 0.2657 0.4224
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0082 0.013
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0033 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0209 0.0505 0.1602
Schistosoma mansoni alpha-1 adrenergic receptor 0.0033 0.0034 0.0034
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.01 0.0196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0034 0.0034
Onchocerca volvulus 0.0057 0.0097 0.03
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0263 0.0419
Entamoeba histolytica hypothetical protein 0.0203 0.049 0.2165
Loa Loa (eye worm) hypothetical protein 0.0336 0.0847 0.1346
Loa Loa (eye worm) thioredoxin reductase 0.0202 0.0487 0.0773
Brugia malayi calpain family protein 1 0.1811 0.4809 0.9299
Giardia lamblia Cathepsin L precursor 0.0203 0.049 0.253
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trichomonas vaginalis calpain, putative 0.0334 0.0842 0.3719
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.003 0.0025 0.004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trypanosoma brucei trypanothione reductase 0.0202 0.0487 0.1544
Loa Loa (eye worm) hypothetical protein 0.0203 0.049 0.0779
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0885 0.2322 0.7368
Entamoeba histolytica aminopeptidase, putative 0.0485 0.1247 0.5505
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0461 0.1182 0.8954
Plasmodium falciparum plasmepsin III 0.0034 0.0036 0.007
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0052 0.0083
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0186 0.0295
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0144 0.0331 0.0527
Schistosoma mansoni calmodulin related calcium binding protein 0.0115 0.0252 0.0252
Trichomonas vaginalis caltractin, putative 0.0027 0.0018 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Loa Loa (eye worm) TYRA-2 protein 0.0033 0.0034 0.0053
Brugia malayi cathepsin B-like cysteine proteinase 0.1946 0.5172 1
Schistosoma mansoni aminopeptidase A (M01 family) 0.0336 0.0847 0.0847
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0009 0.0029
Onchocerca volvulus 0.0146 0.0336 0.1207
Loa Loa (eye worm) animal heme peroxidase 0.0071 0.0135 0.0214
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0203 0.049 0.2165
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0841 0.2205 0.6996
Leishmania major hypothetical protein, conserved 0.0552 0.1427 0.4529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0471 0.121 0.3838
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Schistosoma mansoni cathepsin F (C01 family) 0.0596 0.1545 0.1545
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0864 0.2265 1
Onchocerca volvulus 0.0034 0.0036 0.0068
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0077 0.015 0.0239
Leishmania major receptor-type adenylate cyclase a-like protein 0.0209 0.0505 0.1602
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0052 0.023
Echinococcus multilocularis glycoprotein Antigen 5 0.0057 0.0097 0.0154
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0485 0.1247 0.1982
Trichomonas vaginalis chromobox protein, putative 0.0043 0.006 0.0266
Plasmodium vivax unspecified product 0.0203 0.049 0.096
Onchocerca volvulus 0.0864 0.2265 0.8513
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0066 0.0129
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0021 0.004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0042 0.0067
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.003 0.0134
Echinococcus granulosus calcium uptake protein 1 0.0117 0.0259 0.0412
Loa Loa (eye worm) calpain family protein 1 0.1344 0.3556 0.5651
Loa Loa (eye worm) hypothetical protein 0.0027 0.0018 0.0028
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0042 0.0186
Brugia malayi cathepsin L precursor 0.0203 0.049 0.0948
Leishmania major small myristoylated protein 4, putative 0.0568 0.1469 0.4662
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0034 0.0053
Schistosoma mansoni lamin 0.0083 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trypanosoma brucei conserved protein 0.0218 0.0529 0.1679
Brugia malayi Protein kinase domain containing protein 0.003 0.0025 0.0049
Echinococcus granulosus calmodulin 0.0115 0.0252 0.0401
Onchocerca volvulus 0.0045 0.0066 0.0183
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0525 0.1355 0.4299
Brugia malayi Trypsin family protein 0.0057 0.0097 0.0187
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0034 0.0053
Loa Loa (eye worm) aspartyl protease 6 0.0034 0.0036 0.0057
Echinococcus granulosus g protein coupled receptor 0.0033 0.0034 0.0053
Leishmania major hypothetical protein, conserved 0.0079 0.0156 0.0496
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0801 0.2096 0.4053
Loa Loa (eye worm) hypothetical protein 0.0268 0.0663 0.1054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.049 0.049
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0156 0.0302
Echinococcus granulosus calpain A 0.0801 0.2096 0.3332
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0385 0.0978 0.1891
Loa Loa (eye worm) calmodulin-like protein 0.0115 0.0252 0.0401
Onchocerca volvulus 0.0596 0.1545 0.5788
Mycobacterium ulcerans flavoprotein disulfide reductase 0.007 0.0132 0.1046
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Schistosoma mansoni lamin 0.0083 0.0168 0.0168
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0025 0.0049
Mycobacterium ulcerans aminopeptidase N PepN 0.0485 0.1247 0.9879
Brugia malayi Papain family cysteine protease containing protein 0.0203 0.049 0.0948
Plasmodium falciparum prefoldin subunit 6, putative 0.0062 0.011 0.0214
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0052 0.0131
Plasmodium falciparum M17 leucyl aminopeptidase 0.0385 0.0978 0.1914
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0042 0.0082
Entamoeba histolytica hypothetical protein 0.0039 0.005 0.022
Onchocerca volvulus 0.0036 0.0042 0.0093
Loa Loa (eye worm) hypothetical protein 0.0268 0.0663 0.1054
Schistosoma mansoni amine GPCR 0.0033 0.0034 0.0034
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0209 0.0505 0.0976
Schistosoma mansoni myosin xvIII 0.0033 0.0034 0.0034
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0542 0.14 0.14
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0334 0.0842 0.3719
Trypanosoma cruzi I/6 autoantigen, putative 0.0115 0.0252 0.0487
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0203 0.049 0.096
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0033 0.0034 0.0053
Trypanosoma cruzi calmodulin, putative 0.0115 0.0252 0.0487
Onchocerca volvulus 0.0864 0.2265 0.8513
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.057 0.4322
Echinococcus granulosus leucine aminopeptidase protein 0.0491 0.1262 0.2006
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0033 0.0034 0.0065
Entamoeba histolytica cysteine protease, putative 0.0203 0.049 0.2165
Loa Loa (eye worm) hypothetical protein 0.1344 0.3556 0.5651
Loa Loa (eye worm) hypothetical protein 0.1946 0.5172 0.822
Trypanosoma cruzi I/6 autoantigen, putative 0.0115 0.0252 0.0487
Brugia malayi Pre-SET motif family protein 0.0651 0.1694 0.3275
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0864 0.2265 1
Onchocerca volvulus 0.0033 0.0034 0.0061
Echinococcus multilocularis leucyl aminopeptidase 0.0077 0.015 0.0239
Trichomonas vaginalis centrin, putative 0.0027 0.0018 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0042 0.0081
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0305 0.0764 0.2423
Plasmodium falciparum M1-family alanyl aminopeptidase 0.1922 0.5108 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0533 0.1377 0.2663
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0864 0.2265 0.36
Plasmodium falciparum thioredoxin reductase 0.007 0.0132 0.0258
Brugia malayi Matrixin family protein 0.0041 0.0055 0.0107
Echinococcus granulosus cysteine protease 0.0471 0.121 0.1923
Trichomonas vaginalis calmodulin, putative 0.0115 0.0252 0.1113
Brugia malayi putative neuropeptide receptor 0.0033 0.0034 0.0065
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.0154
Echinococcus granulosus cathepsin L 0.0471 0.121 0.1923
Echinococcus granulosus glycoprotein Antigen 5 0.0057 0.0097 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0203 0.049 0.0779
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0034 0.0034
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0117 0.0259 0.0259
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0034 0.0034
Brugia malayi neuropeptide F receptor 0.0033 0.0034 0.0065
Leishmania major cathepsin L-like protease 0.1194 0.3152 1
Trichomonas vaginalis calcium binding proteins, putative 0.0115 0.0252 0.1113
Loa Loa (eye worm) glutathione reductase 0.0202 0.0487 0.0773
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0543 0.1403 0.2713
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0209 0.0505 0.1602
Plasmodium falciparum glutathione reductase 0.0202 0.0487 0.0953
Echinococcus granulosus expressed conserved protein 0.0046 0.0067 0.0107
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0265 0.0655 0.2078
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0077 0.015 0.029
Plasmodium falciparum plasmepsin X 0.0034 0.0036 0.007
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0009 0.0017
Leishmania major cathepsin L-like protease 0.0864 0.2265 0.7186
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Echinococcus granulosus tar DNA binding protein 0.0062 0.011 0.0175
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0106 0.0228 0.0228
Brugia malayi Peptidase family M1 containing protein 0.0944 0.2479 0.4794
Trypanosoma brucei calmodulin, putative 0.0117 0.0259 0.0822
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1811 0.4809 0.4809
Toxoplasma gondii EFHC1, putative 0.0115 0.0252 0.0493
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0115 0.0252 0.08
Onchocerca volvulus 0.0045 0.0066 0.0183
Brugia malayi hypothetical protein 0.0034 0.0036 0.0069
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0268 0.0663 0.1283
Plasmodium vivax thioredoxin reductase, putative 0.0202 0.0487 0.0953
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0115 0.0252 0.1113
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0336 0.0847 0.1658
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0265 0.0655 0.2078
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.003 0.0057
Onchocerca volvulus 0.0033 0.0034 0.0061
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0115 0.0223
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0033
Toxoplasma gondii aminopeptidase n, putative 0.1922 0.5108 1
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0263 0.1733
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0081 0.0162 0.0313
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0034 0.0034
Schistosoma mansoni adenoreceptor 0.0033 0.0034 0.0034
Trypanosoma cruzi conserved protein 0.0552 0.1427 0.276
Toxoplasma gondii calcium binding protein precursor, putative 0.0027 0.0018 0.0034
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0042 0.0042
Echinococcus multilocularis somatostatin receptor 0.0033 0.0034 0.0053
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0336 0.0847 0.0847
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.007 0.0132 0.021
Trichomonas vaginalis calmodulin, putative 0.0115 0.0252 0.1113
Trypanosoma cruzi calmodulin, putative 0.0115 0.0252 0.0487
Echinococcus granulosus serotonin receptor 0.0033 0.0034 0.0053
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.005 0.0079 0.0154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.007 0.0132 0.0255
Echinococcus granulosus allatostatin A receptor 0.0033 0.0034 0.0053
Schistosoma mansoni amine GPCR 0.0033 0.0034 0.0034
Loa Loa (eye worm) glutamate receptor 0.0044 0.0062 0.0098
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0848 0.2223 0.3533
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0077 0.015 0.0476
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0115 0.0252 0.1113
Brugia malayi Dopamine receptor 0.0033 0.0034 0.0065
Trypanosoma cruzi small myristoylated protein 1-2 0.036 0.0912 0.1763
Echinococcus granulosus cathepsin L cysteine proteinase 0.0864 0.2265 0.36
Echinococcus granulosus aminopeptidase N 0.0944 0.2479 0.394
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0334 0.0842 0.2673
Loa Loa (eye worm) hypothetical protein 0.0336 0.0847 0.1346
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0021 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0742 0.1938 0.8558
Loa Loa (eye worm) cysteine protease 0.0864 0.2265 0.36
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Giardia lamblia Cathepsin B precursor 0.0742 0.1938 1
Giardia lamblia Cathepsin B precursor 0.0742 0.1938 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0033 0.0034 0.0053
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0036 0.0036
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0203 0.049 0.096
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0115 0.037
Brugia malayi Matrixin family protein 0.0041 0.0055 0.0107
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0077 0.015 0.0476
Trypanosoma brucei unspecified product 0.0209 0.0505 0.1602
Trichomonas vaginalis calmodulin, putative 0.0115 0.0252 0.1113
Schistosoma mansoni amine GPCR 0.0033 0.0034 0.0034
Brugia malayi Blistered cuticle protein 3 0.0064 0.0115 0.0223
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.003 0.1151
Toxoplasma gondii cathepsin CPC1 0.0203 0.049 0.096
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0021 0.0065
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0543 0.1403 0.2713
Echinococcus granulosus sex peptide receptor 0.0033 0.0034 0.0053
Giardia lamblia Calmodulin 0.0027 0.0018 0.0091
Onchocerca volvulus Peroxidasin homolog 0.0071 0.0135 0.0443
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0034 0.0053
Toxoplasma gondii calmodulin, putative 0.0027 0.0018 0.0034
Schistosoma mansoni peroxidasin 0.0073 0.014 0.014
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Brugia malayi Papain family cysteine protease containing protein 0.0203 0.049 0.0948
Onchocerca volvulus 0.0033 0.0034 0.0061
Brugia malayi Peptidase family M1 containing protein 0.0336 0.0847 0.1637
Plasmodium vivax vivapain-2 0.0864 0.2265 0.4434
Schistosoma mansoni flap endonuclease-1 0.0026 0.0013 0.0013
Echinococcus granulosus g protein coupled receptor 0.0033 0.0034 0.0053
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0263 0.0263
Brugia malayi hypothetical protein 0.0336 0.0847 0.1637
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0385 0.0978 0.3103
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0336 0.0847 0.1637
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0485 0.1247 0.1982
Trypanosoma brucei aminopeptidase, putative 0.0336 0.0847 0.2687
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0252 0.1113
Echinococcus multilocularis sex peptide receptor 0.0033 0.0034 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0322 0.0322
Brugia malayi putative neuropeptide receptor NPR1 0.0033 0.0034 0.0065
Schistosoma mansoni hypothetical protein 0.0059 0.0102 0.0102
Schistosoma mansoni memapsin-2 (A01 family) 0.0034 0.0036 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0156 0.0302
Toxoplasma gondii EF hand domain-containing protein 0.0115 0.0252 0.0493
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0066 0.0209
Loa Loa (eye worm) hypothetical protein 0.0041 0.0055 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0203 0.049 0.2165
Trypanosoma cruzi small myristoylated protein 1-1 0.036 0.0912 0.1763
Trypanosoma cruzi centrin, putative 0.0142 0.0326 0.0629
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0263 0.1163
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0042 0.0319
Loa Loa (eye worm) hypothetical protein 0.0115 0.0252 0.0401
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0864 0.2265 0.4434
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0336 0.0847 0.3739
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0688 0.1793 0.3467
Onchocerca volvulus Deterin homolog 0.0081 0.0162 0.0548
Brugia malayi EF hand family protein 0.0117 0.0259 0.0501
Echinococcus granulosus cathepsin L 0.0203 0.049 0.0779
Echinococcus multilocularis EF hand domain containing family member A2 0.0117 0.0259 0.0412
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0066 0.0105
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0115 0.0183
Schistosoma mansoni hypothetical protein 0.0039 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Brugia malayi EF hand family protein 0.0115 0.0252 0.0487
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0033 0.0034 0.0053
Onchocerca volvulus Peroxidasin homolog 0.0071 0.0135 0.0443
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0137 0.0217
Onchocerca volvulus 0.0033 0.0034 0.0061
Toxoplasma gondii aspartyl protease 0.0034 0.0036 0.007
Echinococcus granulosus geminin 0.0346 0.0874 0.1389
Echinococcus granulosus prefoldin subunit 6 0.0062 0.011 0.0174
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0033 0.0034 0.0053
Leishmania major dihydrolipoamide dehydrogenase, putative 0.007 0.0132 0.0419
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0033 0.0034 0.0034
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0042 0.0319
Trypanosoma cruzi prefoldin subunit, putative 0.0062 0.011 0.0212
Echinococcus granulosus calpain 7 C02 family 0.0801 0.2096 0.3332
Echinococcus granulosus cathepsin b 0.1946 0.5172 0.822
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0097 0.0097
Trypanosoma brucei I/6 autoantigen 0.0115 0.0252 0.08
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0885 0.2322 0.7368
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0018 0.0077
Plasmodium falciparum calpain 0.0334 0.0842 0.1649
Loa Loa (eye worm) hypothetical protein 0.0083 0.0168 0.0267
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0041 0.0055 0.0055
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0156 0.0306
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0203 0.049 0.0779
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Trypanosoma cruzi cysteine peptidase, putative 0.1194 0.3152 0.6094
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0885 0.2322 0.449
Trichomonas vaginalis esterase, putative 0.0036 0.0042 0.0186
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0033 0.0034 0.0034
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0036 0.0042 0.0066
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0471 0.121 0.121
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.013
Echinococcus multilocularis allatostatin A receptor 0.0033 0.0034 0.0053
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0688 0.1793 0.3467
Trichomonas vaginalis calmodulin, putative 0.0115 0.0252 0.1113
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Brugia malayi larval opioid receptor 0.0033 0.0034 0.0065
Echinococcus granulosus programmed cell death protein 0.0142 0.0326 0.0517
Loa Loa (eye worm) hypothetical protein 0.0034 0.0036 0.0057
Trypanosoma brucei calpain-like protein, putative 0.0801 0.2096 0.6651
Trypanosoma cruzi prefoldin subunit, putative 0.0062 0.011 0.0212
Schistosoma mansoni hypothetical protein 0.0115 0.0252 0.0252
Entamoeba histolytica calmodulin, putative 0.0115 0.0252 0.1113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0196 0.0196
Plasmodium falciparum cysteine proteinase falcipain 3 0.0864 0.2265 0.4434
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0042 0.0186
Trichomonas vaginalis centrin, putative 0.0027 0.0018 0.0077
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0885 0.2322 0.7368
Plasmodium falciparum serine repeat antigen 8 0.0203 0.049 0.096
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0115 0.0252 0.0252
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.0196 0.0312
Loa Loa (eye worm) hypothetical protein 0.005 0.0079 0.0126
Schistosoma mansoni biogenic amine receptor 0.0033 0.0034 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.0853 0.1649
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0115 0.0252 0.0401
Plasmodium vivax plasmepsin V, putative 0.0034 0.0036 0.007
Brugia malayi KE2 family protein 0.0062 0.011 0.0212
Plasmodium falciparum serine repeat antigen 7 0.0203 0.049 0.096
Giardia lamblia Programmed cell death protein-like protein 0.0027 0.0018 0.0091
Echinococcus granulosus netrin receptor unc 5 0.0039 0.005 0.0079
Echinococcus granulosus neuropeptide receptor 0.0033 0.0034 0.0053
Echinococcus granulosus g-protein coupled receptor 0.0033 0.0034 0.0053
Echinococcus multilocularis Calcium binding protein 0.0027 0.0018 0.0028
Plasmodium falciparum plasmepsin V 0.0034 0.0036 0.007
Mycobacterium ulcerans aminopeptidase N PepN 0.0336 0.0847 0.6711
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0033 0.0034 0.0053
Echinococcus multilocularis cysteine protease 0.0864 0.2265 0.36
Schistosoma mansoni hypothetical protein 0.0346 0.0874 0.0874
Leishmania major hypothetical protein, conserved 0.0209 0.0505 0.1602
Brugia malayi hypothetical protein 0.0034 0.0036 0.0069
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0021 0.0033
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0042 0.0081
Echinococcus multilocularis tar DNA binding protein 0.0062 0.011 0.0175
Brugia malayi GnHR receptor homolog 0.0033 0.0034 0.0065
Schistosoma mansoni survival motor neuron protein 0.0047 0.007 0.007
Mycobacterium tuberculosis Conserved protein 0.0036 0.0042 0.0319
Echinococcus granulosus chromobox protein 1 0.0072 0.0137 0.0217
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.0154
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.007 0.0132 0.0258
Echinococcus multilocularis dro:myosuppressin receptor 0.0033 0.0034 0.0053
Leishmania major META domain containing protein 0.0209 0.0505 0.1602
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Schistosoma mansoni chromobox protein 0.0072 0.0137 0.0137
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Schistosoma mansoni hypothetical protein 0.0081 0.0162 0.0162
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0033 0.0034 0.0053
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0097 0.0154
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0263 0.1163
Loa Loa (eye worm) cathepsin B 0.0742 0.1938 0.3081
Trypanosoma cruzi aminopeptidase, putative 0.0336 0.0847 0.1637
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0485 0.1247 0.1982
Loa Loa (eye worm) calpain 0.0801 0.2096 0.3332
Brugia malayi calpain family protein 1 0.1811 0.4809 0.9299
Trypanosoma brucei antigen, putative 0.0801 0.2096 0.6651
Echinococcus multilocularis neuronal calcium sensor 0.0115 0.0252 0.0401
Echinococcus multilocularis chromobox protein 1 0.0072 0.0137 0.0217
Trypanosoma cruzi cysteine peptidase, putative 0.0471 0.121 0.2339
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.007 0.0132 0.1046
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0265 0.0655 0.2078
Schistosoma mansoni tar DNA-binding protein 0.0062 0.011 0.011
Echinococcus multilocularis dna polymerase eta 0.0045 0.0066 0.0105
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0543 0.1403 0.2713
Toxoplasma gondii prefoldin subunit 6, putative 0.0062 0.011 0.0214
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0077 0.015 0.0239
Giardia lamblia NADH oxidase lateral transfer candidate 0.007 0.0132 0.0681
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0203 0.049 0.096
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0033 0.0034 0.0065
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0144 0.0331 0.0527
Loa Loa (eye worm) hypothetical protein 0.0596 0.1545 0.2456
Toxoplasma gondii cathepsin CPL 0.0864 0.2265 0.4434
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.007 0.0132 0.0419
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0461 0.1182 0.8919
Leishmania major centrin, putative,caltractin, putative 0.0115 0.0252 0.08
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0599 0.1553 0.4929
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0057 0.0097 0.0154
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0042 0.0042
Entamoeba histolytica calmodulin, putative 0.0115 0.0252 0.1113
Brugia malayi hypothetical protein 0.0062 0.011 0.0213
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0669 0.174 0.2766
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0485 0.1247 0.3956
Schistosoma mansoni chromobox protein 0.0072 0.0137 0.0137
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0263 0.0419
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0033 0.0034 0.0034
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.007 0.0132 0.021
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Entamoeba histolytica calmodulin, putative 0.0027 0.0018 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.049 0.2165
Trypanosoma cruzi cysteine peptidase, putative 0.1194 0.3152 0.6094
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Trichomonas vaginalis set domain proteins, putative 0.0741 0.1935 0.8545
Schistosoma mansoni tar DNA-binding protein 0.0062 0.011 0.011
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.007 0.0132 0.0419
Leishmania major cathepsin L-like protease 0.0864 0.2265 0.7186
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0144 0.0331 0.0649
Trypanosoma cruzi cysteine proteinase, putative 0.0471 0.121 0.2339
Schistosoma mansoni DNA polymerase eta 0.0045 0.0066 0.0066
Brugia malayi Eukaryotic aspartyl protease family protein 0.0034 0.0036 0.0069
Trypanosoma brucei calpain-like protein, putative 0.0801 0.2096 0.6651
Brugia malayi calpain 5 0.0334 0.0842 0.1629
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.003 0.0058
Schistosoma mansoni leucine aminopeptidase 0.0077 0.015 0.015
Trypanosoma brucei Calpain-like protein 2 0.067 0.1745 0.5537
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0105
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0115 0.0252 0.0487
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0885 0.2322 0.449
Treponema pallidum NADH oxidase 0.007 0.0132 0.5011
Brugia malayi Pepsin A precursor 0.0034 0.0036 0.0069
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0801 0.2096 0.4053
Entamoeba histolytica cysteine protease, putative 0.0203 0.049 0.2165
Loa Loa (eye worm) hypothetical protein 0.0149 0.0344 0.0547
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Echinococcus multilocularis cathepsin L 0.0471 0.121 0.1923
Giardia lamblia Hypothetical protein 0.0203 0.049 0.253
Giardia lamblia Cathepsin B precursor 0.0203 0.049 0.253
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.007 0.0132 0.0255
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.007 0.0132 0.1046
Schistosoma mansoni cathepsin F (C01 family) 0.0864 0.2265 0.2265
Leishmania major small myristoylated protein-3, putative 0.0305 0.0764 0.2423
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0764 0.1477
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0034 0.0053
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0156 0.0306
Loa Loa (eye worm) hypothetical protein 0.0596 0.1545 0.2456
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0033 0.0034 0.0053
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1925 0.5117 0.8134
Brugia malayi cathepsin Z-like cysteine proteinase 0.0203 0.049 0.0948
Loa Loa (eye worm) hypothetical protein 0.0036 0.0041 0.0065
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0543 0.1403 0.2713
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0034 0.0034
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0077 0.015 0.0239
Leishmania major programmed cell death 6 protein-like protein 0.0115 0.0252 0.08
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0203 0.049 0.2165
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.007 0.0132 0.0419
Brugia malayi Trypsin family protein 0.0057 0.0097 0.0187
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Toxoplasma gondii thioredoxin reductase 0.0202 0.0487 0.0953
Schistosoma mansoni calpain C (C02 family) 0.0801 0.2096 0.2096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.003 0.0059
Echinococcus granulosus apoptotic protease activating factor 1 0.0062 0.011 0.0175
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0485 0.1247 0.2411
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0105
Brugia malayi Death domain containing protein 0.003 0.0025 0.0049
Trypanosoma brucei calpain-like protein, putative 0.1066 0.2807 0.8907
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0042 0.0133
Plasmodium vivax aspartyl protease, putative 0.0034 0.0036 0.007
Entamoeba histolytica cysteine protease, putative 0.0203 0.049 0.2165
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0203 0.049 0.049
Toxoplasma gondii microneme protein MIC17B 0.0045 0.0066 0.0129
Echinococcus granulosus peroxidasin 0.008 0.0159 0.0253
Loa Loa (eye worm) matrixin family protein 0.01 0.0213 0.0338
Onchocerca volvulus 0.0045 0.0066 0.0183
Onchocerca volvulus Cathepsin F homolog 0.0864 0.2265 0.8513
Onchocerca volvulus 0.0033 0.0034 0.0061
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1066 0.2807 0.5428
Trypanosoma cruzi major cysteine proteinase, putative 0.0203 0.049 0.0948
Onchocerca volvulus 0.0036 0.0042 0.0093
Echinococcus granulosus intermediate filament protein 0.0083 0.0168 0.0267
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0042 0.0067
Mycobacterium tuberculosis Conserved protein 0.0036 0.0042 0.0319
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0042 0.0333
Leishmania major small myristoylated protein-2 0.0656 0.1707 0.5417
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.003 0.0059
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0485 0.1247 0.1982
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.007 0.0132 0.0255
Onchocerca volvulus 0.0036 0.0042 0.0093
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0025 0.004
Loa Loa (eye worm) hypothetical protein 0.1477 0.3911 0.6216
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0336 0.0847 0.1346
Brugia malayi neuropeptide F receptor 0.0033 0.0034 0.0065
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1946 0.5172 0.5172
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0334 0.0842 0.3719
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0105
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0203 0.049 0.0948
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1066 0.2807 0.8907
Brugia malayi Cathepsin L-like precursor 0.0864 0.2265 0.4379
Schistosoma mansoni Mername-AA248 (C02 family) 0.0801 0.2096 0.2096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0066 0.0129
Echinococcus granulosus caspase 2 0.0062 0.011 0.0175
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0864 0.2265 0.4434
Echinococcus granulosus sodium channel protein 0.0036 0.0042 0.0066
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.067 0.1745 0.5537
Plasmodium falciparum centrin-1 0.0115 0.0252 0.0493
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0028 0.0044
Brugia malayi Receptor family ligand binding region containing protein 0.0029 0.0021 0.004
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.003 0.0134
Brugia malayi cathepsin Z-like cysteine proteinase 0.0203 0.049 0.0948
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0041 0.0055 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0062 0.011 0.011
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.0028 0.022
Loa Loa (eye worm) hypothetical protein 0.0149 0.0344 0.0547
Loa Loa (eye worm) CYP4Cod1 0.0031 0.0028 0.0044
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0885 0.2322 0.449
Entamoeba histolytica cysteine proteinase, putative 0.0471 0.121 0.5341
Echinococcus granulosus nuclear factor of activated T cells 5 0.0155 0.0361 0.0574
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0992 0.2609 0.5044
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.0154
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0551 0.1424 0.2753
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0485 0.1247 0.1982
Brugia malayi Matrixin family protein 0.0041 0.0055 0.0107
Echinococcus granulosus Calcium binding protein 0.0027 0.0018 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0034 0.0053
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0034 0.0053
Plasmodium vivax aspartyl protease, putative 0.0034 0.0036 0.007
Plasmodium falciparum serine repeat antigen 1 0.0203 0.049 0.096
Schistosoma mansoni thyroid hormone receptor 0.0138 0.0314 0.0314
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0066 0.0129
Loa Loa (eye worm) hypothetical protein 0.0203 0.049 0.0779
Trypanosoma brucei calmodulin, putative 0.0115 0.0252 0.08
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0036 0.0036
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0036 0.0036
Plasmodium falciparum serine repeat antigen 6 0.0203 0.049 0.096
Echinococcus multilocularis leucine aminopeptidase protein 0.0491 0.1262 0.2006
Schistosoma mansoni cpg binding protein 0.0031 0.0026 0.0026
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.005 0.0079
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Onchocerca volvulus 0.0045 0.0066 0.0183
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0034 0.0053
Echinococcus granulosus fmrfamide receptor 0.0033 0.0034 0.0053
Entamoeba histolytica cysteine proteinase, putative 0.0864 0.2265 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0042 0.0319
Loa Loa (eye worm) hypothetical protein 0.003 0.0025 0.004
Plasmodium falciparum cysteine repeat modular protein 1 0.012 0.0267 0.0523
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0764 0.1477
Echinococcus multilocularis lamin dm0 0.0083 0.0168 0.0267
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0021 0.0106
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0033 0.0034 0.0053
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0485 0.1247 0.1982
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0033 0.0034 0.0053
Trypanosoma brucei centrin, putative 0.0115 0.0252 0.08
Entamoeba histolytica calpain large subunit domain III containing protein 0.0467 0.1198 0.5289
Onchocerca volvulus 0.0057 0.0097 0.03
Echinococcus multilocularis neuropeptide receptor A26 0.0033 0.0034 0.0053
Echinococcus multilocularis neuropeptide s receptor 0.0033 0.0034 0.0053
Entamoeba histolytica protein kinase, putative 0.0467 0.1198 0.5289
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0115 0.0252 0.0487
Trypanosoma cruzi Aminopeptidase M1, putative 0.0485 0.1247 0.2411
Plasmodium falciparum plasmepsin VII 0.0034 0.0036 0.007
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0034 0.0034
Loa Loa (eye worm) myosin Light Chain family member 0.003 0.0025 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Brugia malayi aspartic protease BmAsp-1, identical 0.0034 0.0036 0.0069
Schistosoma mansoni cathepsin S (C01 family) 0.0203 0.049 0.049
Brugia malayi Tachykinin-like peptides receptor 99D 0.0033 0.0034 0.0065
Plasmodium falciparum thioredoxin reductase 0.0202 0.0487 0.0953
Trichomonas vaginalis calpain, putative 0.0334 0.0842 0.3719
Echinococcus multilocularis prefoldin subunit 6 0.0062 0.011 0.0174
Echinococcus multilocularis caspase 2 0.0062 0.011 0.0175
Giardia lamblia Cathepsin L precursor 0.0203 0.049 0.253
Schistosoma mansoni hypothetical protein 0.0057 0.0097 0.0097
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.0034 0.0036 0.0057
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0082 0.0158
Trypanosoma brucei cytochrome P450, putative 0.0031 0.0028 0.0088
Toxoplasma gondii aminopeptidase N, putative 0.1922 0.5108 1
Brugia malayi Cathepsin L-like precursor 0.0864 0.2265 0.4379
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.007 0.0132 0.0255
Schistosoma mansoni neuronal calcium sensor 0.0115 0.0252 0.0252
Plasmodium vivax plasmepsin IV, putative 0.0144 0.0331 0.0649
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Plasmodium vivax prefoldin subunit 6, putative 0.0062 0.011 0.0214
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0066 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0203 0.049 0.2165
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0144 0.0331 0.0527
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0097 0.0097
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0471 0.121 0.121
Echinococcus granulosus peptide allatostatin:somatostatin 0.0033 0.0034 0.0053
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0841 0.2205 0.6996
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.003 0.0134
Echinococcus multilocularis leucyl aminopeptidase 0.0077 0.015 0.0239
Trypanosoma brucei cysteine peptidase C (CPC) 0.0742 0.1938 0.615
Toxoplasma gondii centrin, putative 0.0115 0.0252 0.0493
Onchocerca volvulus 0.0045 0.0066 0.0183
Onchocerca volvulus 0.0041 0.0055 0.0143
Toxoplasma gondii hypothetical protein 0.0045 0.0066 0.0129
Giardia lamblia Cathepsin L-like protease 0.0203 0.049 0.253
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0512 0.132 1
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.0036 0.0042 0.0067
Onchocerca volvulus Peroxidase homolog 0.0064 0.0115 0.037
Plasmodium vivax cysteine repeat modular protein 1, putative 0.012 0.0267 0.0523
Entamoeba histolytica grainin, putative 0.0117 0.0259 0.1144
Brugia malayi Kringle domain containing protein 0.012 0.0267 0.0517
Mycobacterium leprae PROBABLE HYDROLASE 0.005 0.0079 0.0293
Plasmodium falciparum plasmepsin VIII, putative 0.0034 0.0036 0.007
Brugia malayi phosphofructokinase 0.0119 0.0263 0.0509
Trypanosoma brucei prefoldin subunit, putative 0.0062 0.011 0.0348
Loa Loa (eye worm) TAR-binding protein 0.0062 0.011 0.0175
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0203 0.049 0.2165
Giardia lamblia Cathepsin L-like protease 0.0203 0.049 0.253
Brugia malayi Immunoglobulin I-set domain containing protein 0.0428 0.1095 0.2117
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0203 0.049 0.2165
Echinococcus multilocularis expressed conserved protein 0.0046 0.0067 0.0107
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0028 0.0054
Echinococcus multilocularis neuropeptide FF receptor 2 0.0033 0.0034 0.0053
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0543 0.1403 0.4452
Trypanosoma cruzi calmodulin, putative 0.0115 0.0252 0.0487
Loa Loa (eye worm) hypothetical protein 0.0036 0.0042 0.0067
Onchocerca volvulus Matrilysin homolog 0.0041 0.0055 0.0143
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Brugia malayi Heterochromatin protein 1 0.0072 0.0137 0.0264
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0336 0.0847 0.1637
Giardia lamblia Cysteine protease 0.0203 0.049 0.253
Echinococcus granulosus Ankyrin 0.0031 0.0026 0.0041
Trypanosoma cruzi kinesin, putative 0.0467 0.1198 0.2316
Onchocerca volvulus 0.0057 0.0097 0.03
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0485 0.1247 0.1247
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0051 0.0082 0.0159
Plasmodium vivax unspecified product 0.0268 0.0663 0.1299
Schistosoma mansoni hypothetical protein 0.0062 0.011 0.011
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0155 0.0361 0.0574
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.003 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Toxoplasma gondii aspartyl protease ASP3 0.0034 0.0036 0.007
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0021 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0034 0.0034
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.007 0.0132 0.0826
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0034 0.0034
Trypanosoma cruzi cysteine protease, putative 0.0471 0.121 0.2339
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.0505 0.0976
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0044 0.0062 0.0062
Trichomonas vaginalis kakapo, putative 0.0027 0.0018 0.0077
Onchocerca volvulus 0.0106 0.0228 0.0797
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0149 0.0344 0.0665
Loa Loa (eye worm) hypothetical protein 0.012 0.0267 0.0425
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Brugia malayi metabotropic glutamate receptor type 2 0.0054 0.009 0.0174
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0137 0.0604
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0034 0.0053
Toxoplasma gondii troponin c, isotype gamma, putative 0.0115 0.0252 0.0493
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0203 0.049 0.253
Schistosoma mansoni tar DNA-binding protein 0.0062 0.011 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Trypanosoma brucei Aminopeptidase M1, putative 0.0485 0.1247 0.3956
Leishmania major calmodulin-like protein 0.0115 0.0252 0.08
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0115 0.0223
Brugia malayi TATA binding protein associated factor 0.0336 0.0847 0.1637
Loa Loa (eye worm) aminopeptidase N 0.0485 0.1247 0.1982
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.007 0.0132 0.0258
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0543 0.1403 0.2713
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0021 0.0065
Echinococcus granulosus survival motor neuron protein 1 0.023 0.0562 0.0893
Echinococcus multilocularis calumenin 0.0117 0.0259 0.0412
Brugia malayi beta-lactamase family protein 0.0036 0.0042 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0322 0.0322
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Onchocerca volvulus 0.0033 0.0034 0.0061
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.0154
Brugia malayi Flap endonuclease-1 0.0028 0.0021 0.004
Brugia malayi RasGEF domain containing protein 0.0027 0.0018 0.0034
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0115 0.0252 0.0487
Onchocerca volvulus 0.0741 0.1936 0.7268
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.003 0.0059
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0263 0.0419
Loa Loa (eye worm) TATA binding protein associated factor 0.0336 0.0847 0.1346
Brugia malayi Hemopexin family protein 0.0059 0.0102 0.0197
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0543 0.1403 0.2713
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0203 0.049 0.2165
Brugia malayi hypothetical protein 0.1674 0.4441 0.8587
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Trypanosoma cruzi caltractin, putative 0.0115 0.0252 0.0487
Loa Loa (eye worm) hypothetical protein 0.0039 0.0048 0.0076
Onchocerca volvulus 0.0203 0.049 0.1791
Leishmania major hypothetical protein, conserved 0.0117 0.0259 0.0822
Brugia malayi Serotonin receptor 0.0033 0.0034 0.0065
Schistosoma mansoni hypothetical protein 0.0062 0.011 0.011
Brugia malayi aspartic protease BmAsp-2, identical 0.0034 0.0036 0.0069
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0081 0.0162 0.0313
Echinococcus multilocularis calcyphosin protein 0.0027 0.0018 0.0028
Leishmania major calpain protease-like protein 0.0334 0.0842 0.2673
Trypanosoma brucei kinesin, putative 0.0467 0.1198 0.38
Trichomonas vaginalis calmodulin, putative 0.0027 0.0018 0.0077
Entamoeba histolytica cysteine proteinase, putative 0.0471 0.121 0.5341
Schistosoma mansoni hypothetical protein 0.0057 0.0097 0.0097
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0334 0.0842 0.1649
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Echinococcus multilocularis thioredoxin glutathione reductase 0.0202 0.0487 0.0773
Giardia lamblia Cathepsin B precursor 0.0203 0.049 0.253
Echinococcus granulosus neuropeptide s receptor 0.0033 0.0034 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0471 0.121 0.3838
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Chlamydia trachomatis cytosol aminopeptidase 0.0491 0.1262 1
Echinococcus multilocularis inhibitor of apoptosis protein 0.0081 0.0162 0.0258
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1946 0.5172 0.5172
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.003 0.0025 0.004
Toxoplasma gondii calmodulin CAM1 0.0117 0.0259 0.0507
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0202 0.0487 0.3687
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0115 0.0252 0.1113
Onchocerca volvulus 0.0045 0.0066 0.0183
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Trypanosoma brucei aminopeptidase, putative 0.0077 0.015 0.0476
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1925 0.5117 0.8134
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0651 0.1694 0.2692
Onchocerca volvulus 0.0029 0.0022 0.0016
Echinococcus multilocularis geminin 0.0346 0.0874 0.1389
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0263 0.1163
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0203 0.049 0.096
Trypanosoma brucei small myristoylated protein 1-2 0.036 0.0912 0.2893
Loa Loa (eye worm) fibroinase 0.0864 0.2265 0.36
Onchocerca volvulus 0.0034 0.0036 0.0068
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Loa Loa (eye worm) hypothetical protein 0.0027 0.0018 0.0028
Echinococcus granulosus G protein coupled receptor 139 0.0033 0.0034 0.0053
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0461 0.1182 0.8954
Toxoplasma gondii preprocathepsin c precursor, putative 0.0203 0.049 0.096
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Echinococcus multilocularis orexin receptor type 2 0.0033 0.0034 0.0053
Giardia lamblia Cathepsin L precursor 0.0203 0.049 0.253
Onchocerca volvulus 0.101 0.2657 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0322 0.0512
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.004 0.004
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0203 0.049 0.253
Schistosoma mansoni opsin-like receptor 0.0033 0.0034 0.0034
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.0154
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Schistosoma mansoni calpain-7 (C02 family) 0.0801 0.2096 0.2096
Onchocerca volvulus Matrilysin homolog 0.0092 0.0191 0.0656
Plasmodium vivax serine-repeat antigen (SERA) 0.0203 0.049 0.096
Echinococcus multilocularis calpain 5 0.0801 0.2096 0.3332
Trichomonas vaginalis calcineurin B subunit, putative 0.0117 0.0259 0.1144
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0045 0.0066 0.0129
Brugia malayi Melatonin receptor type 1A 0.0033 0.0034 0.0065
Loa Loa (eye worm) hypothetical protein 0.0268 0.0663 0.1054
Plasmodium vivax unspecified product 0.0471 0.121 0.2368
Schistosoma mansoni amine GPCR 0.0033 0.0034 0.0034
Brugia malayi 6-phosphofructokinase 0.0119 0.0263 0.0509
Echinococcus granulosus cathepsin l1 0.0596 0.1545 0.2456
Brugia malayi Dopamine receptor protein 1 0.0033 0.0034 0.0065
Echinococcus granulosus neuronal calcium sensor 0.0115 0.0252 0.0401
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.007 0.0132 0.0255
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0864 0.2265 1
Trypanosoma brucei caltractin, putative 0.0142 0.0326 0.1033
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0033 0.0034 0.0065
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0203 0.049 0.253
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0322 0.0512
Echinococcus multilocularis calpain A 0.1928 0.5125 0.8145
Onchocerca volvulus 0.0057 0.0097 0.03
Echinococcus granulosus EF hand domain containing family member A2 0.0115 0.0252 0.0401
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0034 0.0036 0.007
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0077 0.015 0.0476
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0115 0.0252 0.1113
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.003 0.0134
Brugia malayi sulfakinin receptor protein 0.0033 0.0034 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0471 0.121 0.5341
Trichomonas vaginalis centrin, putative 0.0027 0.0018 0.0077
Leishmania major hypothetical protein, conserved 0.0209 0.0505 0.1602
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.0174
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0543 0.1403 0.4452
Entamoeba histolytica cysteine protease, putative 0.0203 0.049 0.2165
Onchocerca volvulus 0.0033 0.0034 0.0061
Schistosoma mansoni calpain (C02 family) 0.0801 0.2096 0.2096
Schistosoma mansoni hypothetical protein 0.0334 0.0842 0.0842
Onchocerca volvulus 0.0045 0.0066 0.0183
Entamoeba histolytica grainin 2 0.0142 0.0326 0.1437
Onchocerca volvulus 0.0032 0.0029 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0203 0.049 0.2165
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Echinococcus granulosus leukotriene A 4 hydrolase 0.2363 0.6292 1
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0485 0.1247 0.5505
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0203 0.049 0.096
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0115 0.0252 0.0401
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0471 0.121 0.5341
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0033 0.0034 0.0065
Leishmania major hypothetical protein, conserved 0.0209 0.0505 0.1602
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0144 0.0331 0.1463
Echinococcus multilocularis serotonin receptor 0.0033 0.0034 0.0053
Echinococcus multilocularis cathepsin L cysteine protease 0.0864 0.2265 0.36
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0057 0.0097 0.0154
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0033 0.0034 0.0053
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0196 0.0312
Trypanosoma cruzi centrin-3 0.0142 0.0326 0.0629
Brugia malayi Cathepsin L-like precursor 0.0596 0.1545 0.2988
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0033 0.0034 0.0053
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0491 0.1262 0.2471
Mycobacterium tuberculosis Conserved protein 0.0036 0.0042 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0052 0.023
Giardia lamblia Cysteine protease 0.0203 0.049 0.253
Loa Loa (eye worm) hypothetical protein 0.0039 0.0048 0.0076
Brugia malayi RE15519p 0.0033 0.0034 0.0065
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.005 0.0079
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0081 0.0162 0.0162
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.0154
Onchocerca volvulus 0.0081 0.0162 0.0548
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0028 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0203 0.049 0.2165
Loa Loa (eye worm) hypothetical protein 0.0334 0.0842 0.1339
Giardia lamblia Hypothetical protein 0.0062 0.011 0.0565
Brugia malayi Papain family cysteine protease containing protein 0.0203 0.049 0.0948
Loa Loa (eye worm) RNA binding protein 0.0062 0.011 0.0175
Schistosoma mansoni cathepsin D (A01 family) 0.0425 0.1086 0.1086
Trichomonas vaginalis glutathione reductase, putative 0.007 0.0132 0.0583
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.007 0.0132 0.1046
Trichomonas vaginalis calcium binding protein, putative 0.0142 0.0326 0.1437
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.007 0.0132 0.0419
Entamoeba histolytica cysteine protease, putative 0.0203 0.049 0.2165
Loa Loa (eye worm) hypothetical protein 0.0608 0.1576 0.2505
Schistosoma mansoni neuropeptide f receptor 76f 0.0033 0.0034 0.0034
Plasmodium falciparum serine repeat antigen 9 0.0203 0.049 0.096
Onchocerca volvulus 0.0045 0.0066 0.0183
Brugia malayi TAR-binding protein 0.0062 0.011 0.0213
Brugia malayi hypothetical protein 0.023 0.0562 0.1086
Schistosoma mansoni hypothetical protein 0.0115 0.0252 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Plasmodium vivax vivapain-2 0.0864 0.2265 0.4434
Onchocerca volvulus 0.0033 0.0034 0.0061
Onchocerca volvulus 0.0033 0.0034 0.0061
Leishmania major trypanothione reductase 0.0202 0.0487 0.1544
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0263 0.0419
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0782 0.2045 0.6488
Plasmodium falciparum plasmepsin IX 0.0034 0.0036 0.007
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.003 0.0059
Schistosoma mansoni centrin-related 0.0115 0.0252 0.0252
Onchocerca volvulus 0.0417 0.1064 0.3962
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0568 0.1469 0.2841
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0525 0.1355 0.4299
Toxoplasma gondii NADPH-glutathione reductase 0.007 0.0132 0.0258
Loa Loa (eye worm) hypothetical protein 0.0203 0.049 0.0779
Schistosoma mansoni peroxidasin 0.0064 0.0115 0.0115
Schistosoma mansoni calmodulin 0.0115 0.0252 0.0252
Schistosoma mansoni histamine h1 receptor 0.0033 0.0034 0.0034
Entamoeba histolytica grainin 2 0.0027 0.0018 0.0077
Brugia malayi G protein-coupled receptor F59B2.13 0.0033 0.0034 0.0065
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0543 0.1403 0.4452
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0263 0.0263
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0336 0.0847 0.1637
Schistosoma mansoni metabotropic glutamate receptor 0.0364 0.0923 0.0923
Brugia malayi cathepsin F-like cysteine proteinase 0.0268 0.0663 0.1283
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Leishmania major cathepsin L-like protease 0.1194 0.3152 1
Echinococcus multilocularis leucyl aminopeptidase 0.0077 0.015 0.0239
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0196 0.0196
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0045 0.0066 0.0066
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.0287 0.0456
Echinococcus granulosus calumenin 0.0117 0.0259 0.0412
Loa Loa (eye worm) beta-lactamase 0.0036 0.0042 0.0067
Onchocerca volvulus 0.0864 0.2265 0.8513
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.0853 0.1649
Entamoeba histolytica cysteine proteinase 2 0.0471 0.121 0.5341
Loa Loa (eye worm) hypothetical protein 0.0203 0.049 0.0779
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0149 0.0344 0.0344
Echinococcus multilocularis tachykinin peptides receptor 99D 0.2073 0.5513 0.8762
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0485 0.1247 0.1982
Entamoeba histolytica calcium binding family protein 0.0115 0.0252 0.1113
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0864 0.2265 1
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.015 0.0348 0.0554
Loa Loa (eye worm) hypothetical protein 0.0203 0.049 0.0779
Echinococcus granulosus dna polymerase eta 0.0045 0.0066 0.0105
Onchocerca volvulus 0.0045 0.0066 0.0183
Echinococcus multilocularis cathepsin L cysteine protease 0.0864 0.2265 0.36
Trypanosoma cruzi unspecified product 0.036 0.0912 0.1763
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1066 0.2807 0.5428
Schistosoma mansoni ankyrin 23/unc44 0.003 0.0025 0.0025
Plasmodium vivax centrin-1, putative 0.0115 0.0252 0.0493
Brugia malayi Metabotropic glutamate receptor precursor. 0.0029 0.0021 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1946 0.5172 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0596 0.1545 0.6824
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.049 0.049
Trypanosoma brucei protein I/6 0.0115 0.0252 0.08
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0081 0.0162 0.0258
Plasmodium vivax hypothetical protein, conserved 0.0117 0.0259 0.0507
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.049 0.2165
Schistosoma mansoni hypothetical protein 0.0033 0.0034 0.0034
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0471 0.121 0.2339
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0066 0.0127
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.003 0.0134
Brugia malayi Peroxidasin 0.008 0.0159 0.0308
Toxoplasma gondii microneme protein MIC4 0.0045 0.0066 0.0129
Echinococcus multilocularis cathepsin L 0.0203 0.049 0.0779
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.003 0.0059
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0782 0.2045 0.6488
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Plasmodium vivax calpain, putative 0.0801 0.2096 0.4103
Echinococcus granulosus calpain 5 0.0801 0.2096 0.3332
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0263 0.1163
Leishmania major cytochrome p450-like protein 0.0031 0.0028 0.0088
Plasmodium falciparum centrin-4 0.0027 0.0018 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0034 0.0034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0322 0.0512
Schistosoma mansoni growth hormone secretagogue receptor 0.0033 0.0034 0.0034
Onchocerca volvulus 0.012 0.0267 0.0946
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0543 0.1403 0.2713
Leishmania major DNA polymerase eta, putative 0.0045 0.0066 0.0209
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0034 0.0053
Leishmania major hypothetical protein, conserved 0.0209 0.0505 0.1602
Toxoplasma gondii hypothetical protein 0.0045 0.0066 0.0129
Mycobacterium ulcerans leucyl aminopeptidase 0.0491 0.1262 1
Brugia malayi Trypsin-like protease protein 5 0.0057 0.0097 0.0187
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.047 0.1207 0.3829
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0077 0.015 0.029
Giardia lamblia Cathepsin L precursor 0.0203 0.049 0.253
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0033 0.0034 0.0053
Echinococcus granulosus hypothetical protein 0.0033 0.0034 0.0053
Leishmania major calcineurin B subunit, putative 0.0115 0.0252 0.08
Loa Loa (eye worm) hypothetical protein 0.0062 0.011 0.0175
Brugia malayi RNA binding protein 0.0062 0.011 0.0213
Echinococcus granulosus calpain 0.0801 0.2096 0.3332
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0115 0.0252 0.08
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0252 0.1113
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0156 0.0496
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0485 0.1247 0.1982
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1925 0.5117 0.5117
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0021 0.0033
Entamoeba histolytica cysteine protease, putative 0.0864 0.2265 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Brugia malayi cytosol aminopeptidase 0.0077 0.015 0.029
Trichomonas vaginalis calcineurin B subunit, putative 0.0115 0.0252 0.1113
Trypanosoma cruzi aminopeptidase, putative 0.0485 0.1247 0.2411
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.007 0.0132 0.0258
Entamoeba histolytica cysteine proteinase, putative 0.0864 0.2265 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0656 0.1706 0.5414
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0334 0.0842 0.3719
Brugia malayi hypothetical protein 0.0051 0.0081 0.0157
Echinococcus multilocularis calpain 0.0801 0.2096 0.3332
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1066 0.2807 0.5428
Schistosoma mansoni neuropeptide receptor 0.0033 0.0034 0.0034
Echinococcus multilocularis programmed cell death protein 0.0142 0.0326 0.0517
Leishmania major cathepsin L-like protease 0.0864 0.2265 0.7186
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0471 0.121 0.121
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0149 0.0344 0.0547
Brugia malayi Cytochrome P450 family protein 0.0031 0.0028 0.0054
Entamoeba histolytica cysteine protease, putative 0.0471 0.121 0.5341
Trichomonas vaginalis calmodulin, putative 0.0115 0.0252 0.1113
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.008 0.0159 0.0253
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0018 0.0034
Brugia malayi glutathione reductase 0.0202 0.0487 0.0941
Onchocerca volvulus 0.0083 0.0168 0.0569
Leishmania major cathepsin L-like protease 0.0864 0.2265 0.7186
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0115 0.0252 0.0487
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0801 0.2096 0.4053
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0052 0.0083
Trichomonas vaginalis hypothetical protein 0.0334 0.0842 0.3719
Onchocerca volvulus 0.0059 0.0102 0.0319
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.005 0.0079 0.0602
Plasmodium vivax vivapain-3 0.0471 0.121 0.2368
Trypanosoma brucei mitochondrial calcium uptake 1 0.0115 0.0252 0.08
Echinococcus granulosus alpha 1A adrenergic receptor 0.0033 0.0034 0.0053
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0034 0.0053
Plasmodium vivax SET domain protein, putative 0.0094 0.0196 0.0385
Echinococcus granulosus enteropeptidase 0.0057 0.0097 0.0154
Brugia malayi Dopamine receptor protein 2 0.0033 0.0034 0.0065
Toxoplasma gondii microneme protein MIC17C 0.0045 0.0066 0.0129
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0033 0.0034 0.0053
Mycobacterium ulcerans hydrolase 0.005 0.0079 0.063
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0105
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.068 0.1772 0.1772
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0322 0.0322
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0334 0.0842 0.2673
Schistosoma mansoni netrin receptor unc5 0.0039 0.005 0.005
Echinococcus granulosus cpg binding protein 0.0031 0.0026 0.0041
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0042 0.0067
Schistosoma mansoni calmodulin-related 0.0027 0.0018 0.0018
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0057 0.0097 0.0154
Schistosoma mansoni cathepsin C 0.0203 0.049 0.049
Echinococcus granulosus tachykinin peptides receptor 99D 0.2073 0.5513 0.8762
Giardia lamblia Cathepsin L precursor 0.0203 0.049 0.253
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.0287 0.0456
Trichomonas vaginalis calcium binding protein, putative 0.0115 0.0252 0.1113
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0263 0.0836
Toxoplasma gondii subtilisin SUB12 0.0045 0.0066 0.0129
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Echinococcus multilocularis hypothetical protein 0.0801 0.2096 0.3332
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.0331 0.0331
Echinococcus multilocularis calpain family protein 1, d 0.1344 0.3556 0.5651
Echinococcus granulosus g protein coupled receptor 0.0033 0.0034 0.0053
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0491 0.1262 0.9561
Trypanosoma cruzi cysteine peptidase, putative 0.0268 0.0663 0.1283
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1925 0.5117 0.5117
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0034 0.0053
Plasmodium falciparum glutathione reductase 0.007 0.0132 0.0258
Trypanosoma cruzi hypothetical protein, conserved 0.012 0.0267 0.0517
Mycobacterium ulcerans hypothetical protein 0.0036 0.0042 0.0333
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0742 0.1938 0.3748
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0599 0.1553 0.4929
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0203 0.049 0.096
Echinococcus granulosus neuropeptide FF receptor 2 0.0033 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.047 0.1207 0.2333
Trypanosoma brucei small myristoylated protein 1-1 0.036 0.0912 0.2893
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Onchocerca volvulus Tyrosine kinase homolog 0.0426 0.109 0.4061
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0066 0.0105
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0066 0.0127
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0334 0.0842 0.3719
Trichomonas vaginalis chromobox protein, putative 0.0043 0.006 0.0266
Brugia malayi Myosin regulatory light chain 1 0.0027 0.0018 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.007 0.0132 0.0255
Brugia malayi beta-lactamase 0.0036 0.0042 0.0081
Loa Loa (eye worm) trypsin family protein 0.0057 0.0097 0.0154
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0033 0.0034 0.0034
Leishmania major hypothetical protein, conserved 0.012 0.0267 0.0848
Schistosoma mansoni hypothetical protein 0.011 0.0239 0.0239
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1066 0.2807 0.8907
Echinococcus multilocularis Ankyrin 0.0031 0.0026 0.0041
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0485 0.1247 0.1982
Loa Loa (eye worm) hypothetical protein 0.0081 0.0162 0.0258
Schistosoma mansoni opsin-like receptor 0.0033 0.0034 0.0034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0688 0.1793 0.569
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0034 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Plasmodium falciparum flap endonuclease 1 0.0028 0.0021 0.004
Schistosoma mansoni inhibitor of apoptosis protein 0.0081 0.0162 0.0162
Onchocerca volvulus Peroxidase homolog 0.0064 0.0115 0.037
Leishmania major hypothetical protein, conserved 0.0338 0.0853 0.2706
Loa Loa (eye worm) calpain family protein 1 0.1811 0.4809 0.7644
Loa Loa (eye worm) matrixin family protein 0.0092 0.0191 0.0303
Echinococcus multilocularis musashi 0.0083 0.0168 0.0267
Toxoplasma gondii aspartyl protease ASP1 0.0144 0.0331 0.0649
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0077 0.015 0.029
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0031 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0864 0.2265 1
Loa Loa (eye worm) RecQ helicase 0.0045 0.0066 0.0104
Trypanosoma brucei Calpain-like protein 1.2 0.0688 0.1793 0.569
Brugia malayi Matrixin family protein 0.01 0.0213 0.0412
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0097 0.0097
Onchocerca volvulus 0.0033 0.0034 0.0061
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.007 0.0132 0.1046
Loa Loa (eye worm) glutamate receptor 0.0029 0.0021 0.0033
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0115 0.0252 0.0401
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.003 0.0134
Onchocerca volvulus 0.0033 0.0034 0.0061
Echinococcus multilocularis tissue type plasminogen activator 0.012 0.0267 0.0425
Brugia malayi Intermediate filament tail domain containing protein 0.0083 0.0168 0.0324
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0336 0.0847 0.2687
Trypanosoma cruzi cysteine proteinase, putative 0.0471 0.121 0.2339
Brugia malayi programmed cell death protein 6 0.0115 0.0252 0.0487
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0115 0.037
Trichomonas vaginalis calmodulin, putative 0.0142 0.0326 0.1437
Plasmodium falciparum plasmepsin VI 0.0144 0.0331 0.0649
Plasmodium falciparum cysteine proteinase falcipain 1 0.0471 0.121 0.2368
Trichomonas vaginalis centrin, putative 0.0115 0.0252 0.1113
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.049 0.049
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0034 0.0034
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0029 0.0021 0.0033
Onchocerca volvulus 0.0033 0.0034 0.0061
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0485 0.1247 0.3956
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.061 0.0969
Onchocerca volvulus 0.0083 0.0168 0.0569
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.011 0.0213
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0042 0.0186
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0083 0.0168 0.0267
Trypanosoma cruzi trypanothione reductase, putative 0.0202 0.0487 0.0941
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0034 0.0034
Echinococcus granulosus neuropeptide receptor 0.0033 0.0034 0.0053
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0064 0.0101
Echinococcus granulosus dro:myosuppressin receptor 0.0033 0.0034 0.0053
Brugia malayi G-protein coupled receptor 0.0033 0.0034 0.0065
Toxoplasma gondii cathepsin CPC2 0.0203 0.049 0.096
Echinococcus granulosus cathepsin L cysteine protease 0.0471 0.121 0.1923
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0034 0.0053
Loa Loa (eye worm) programmed cell death protein 6 0.0117 0.0259 0.0412
Echinococcus granulosus neuropeptide receptor A26 0.0033 0.0034 0.0053
Toxoplasma gondii calmodulin CAM2 0.0027 0.0018 0.0034
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0105
Brugia malayi beta-lactamase family protein 0.0036 0.0042 0.0081
Echinococcus multilocularis apoptotic protease activating factor 1 0.0062 0.011 0.0175
Echinococcus multilocularis neurocalcin 0.0115 0.0252 0.0401
Schistosoma mansoni hypothetical protein 0.0346 0.0874 0.0874
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Echinococcus multilocularis calcium uptake protein 1 0.0117 0.0259 0.0412
Mycobacterium tuberculosis Probable reductase 0.0461 0.1182 0.8954
Loa Loa (eye worm) hypothetical protein 0.0146 0.0336 0.0534
Schistosoma mansoni neuropeptide receptor 0.0033 0.0034 0.0034
Echinococcus multilocularis leukotriene A 4 hydrolase 0.2363 0.6292 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0202 0.0487 0.0773
Brugia malayi Cell death protein 3 precursor 0.0062 0.011 0.0213
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0066 0.0105
Trypanosoma brucei Component of motile flagella 41 0.0115 0.0252 0.08
Echinococcus multilocularis g-protein coupled receptor 0.0033 0.0034 0.0053
Brugia malayi G-protein coupled receptor 0.0033 0.0034 0.0065
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0105
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0066 0.029
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Toxoplasma gondii aminopeptidase N protein 0.1922 0.5108 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.0154
Brugia malayi hypothetical protein 0.0064 0.0115 0.0223
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0034 0.0053
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0042 0.0333
Leishmania major cathepsin L-like protease 0.1194 0.3152 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Onchocerca volvulus 0.0064 0.0115 0.037
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0115 0.0223
Entamoeba histolytica hypothetical protein 0.0039 0.005 0.022
Giardia lamblia Encystation-specific protease 0.0203 0.049 0.253
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0009 0.004
Loa Loa (eye worm) hypothetical protein 0.0459 0.1176 0.187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.005 0.0097
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0334 0.0842 0.3719
Onchocerca volvulus 0.0864 0.2265 0.8513
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0525 0.1355 0.262
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0462 0.1184 0.2289
Leishmania major prefoldin subunit, putative 0.0062 0.011 0.0348
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Brugia malayi Trypsin family protein 0.0057 0.0097 0.0187
Schistosoma mansoni cpg binding protein 0.0031 0.0026 0.0026
Onchocerca volvulus 0.0864 0.2265 0.8513
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0077 0.015 0.0476
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0064 0.0123
Echinococcus multilocularis Mastin 0.0057 0.0097 0.0154
Schistosoma mansoni neuropeptide receptor 0.0033 0.0034 0.0034
Brugia malayi Peptidase family M1 containing protein 0.0485 0.1247 0.2411
Trichomonas vaginalis mercuric reductase, putative 0.007 0.0132 0.0583
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0027 0.0018 0.0077
Plasmodium falciparum plasmepsin I 0.0144 0.0331 0.0649
Onchocerca volvulus 0.0117 0.0259 0.0915
Loa Loa (eye worm) peptidase family M1 containing protein 0.0795 0.2079 0.3305
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0209 0.0505 0.1602
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.003 0.0156
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0203 0.049 0.2165
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0027 0.0018 0.0034
Toxoplasma gondii hypothetical protein 0.0334 0.0842 0.1649
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0209 0.0505 0.1602
Trichomonas vaginalis conserved hypothetical protein 0.0334 0.0842 0.3719
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0033 0.0034 0.0034
Trichomonas vaginalis calmodulin, putative 0.0117 0.0259 0.1144
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0009 0.0029
Onchocerca volvulus 0.0045 0.0066 0.0183
Leishmania major kinesin, putative 0.0467 0.1198 0.38
Leishmania major dihydrolipoamide dehydrogenase, putative 0.007 0.0132 0.0419
Echinococcus granulosus leucyl aminopeptidase 0.0077 0.015 0.0239
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Schistosoma mansoni rab 0.0115 0.0252 0.0252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0864 0.2265 1
Echinococcus multilocularis calbindin 32 0.0117 0.0259 0.0412
Brugia malayi hypothetical protein 0.0033 0.0034 0.0065
Entamoeba histolytica hypothetical protein 0.0039 0.005 0.022
Brugia malayi MH2 domain containing protein 0.0248 0.061 0.1179
Toxoplasma gondii cathepsin B 0.0742 0.1938 0.3794
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0864 0.2265 0.36
Echinococcus granulosus Mastin 0.0057 0.0097 0.0154
Echinococcus granulosus transmembrane protease serine 3 0.0057 0.0097 0.0154
Schistosoma mansoni myosin regulatory light chain 0.0027 0.0018 0.0018
Entamoeba histolytica calpain family cysteine protease, putative 0.0334 0.0842 0.3719
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0203 0.049 0.049
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0203 0.049 0.096
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0097 0.0097
Schistosoma mansoni cpg binding protein 0.0029 0.0022 0.0022
Loa Loa (eye worm) melatonin receptor type 1A 0.0033 0.0034 0.0053
Echinococcus multilocularis lamin 0.0083 0.0168 0.0267
Trypanosoma brucei hypothetical protein, conserved 0.0338 0.0853 0.2706
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0034 0.0053
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0034 0.0053
Onchocerca volvulus 0.0062 0.011 0.035
Schistosoma mansoni hypothetical protein 0.0033 0.0034 0.0034
Echinococcus multilocularis peroxidasin 0.008 0.0159 0.0253
Echinococcus multilocularis sodium channel protein 0.0036 0.0042 0.0066
Schistosoma mansoni biogenic amine receptor 0.0033 0.0034 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Loa Loa (eye worm) matrix metalloproteinase 0.0041 0.0055 0.0088
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0034 0.0034
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.061 0.0969
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.049 0.2165
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0034 0.0053
Schistosoma mansoni hypothetical protein 0.0047 0.007 0.007
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0066 0.0127
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0203 0.049 0.0779
Toxoplasma gondii PAN/Apple domain-containing protein 0.0045 0.0066 0.0129
Brugia malayi Thioredoxin reductase 0.0202 0.0487 0.0941
Schistosoma mansoni centrin 0.0115 0.0252 0.0252
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0036 0.0036
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0081 0.0162 0.0258
Echinococcus granulosus neurocalcin 0.0115 0.0252 0.0401
Mycobacterium ulcerans hypothetical protein 0.0057 0.0097 0.0767
Trypanosoma cruzi cruzipain precursor, putative 0.0268 0.0663 0.1283
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Brugia malayi hypothetical protein 0.0485 0.1247 0.2411
Loa Loa (eye worm) hypothetical protein 0.0027 0.0018 0.0028
Giardia lamblia Cathepsin B precursor 0.0203 0.049 0.253
Echinococcus granulosus metabotropic glutamate receptor 5 0.0054 0.009 0.0143
Entamoeba histolytica hypothetical protein, conserved 0.0117 0.0259 0.1144
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0864 0.2265 1
Leishmania major centrin, putative 0.0115 0.0252 0.08
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0801 0.2096 0.4053
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.007 0.0135
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0485 0.1247 0.3956
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0036 0.0042 0.0132
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Schistosoma mansoni hypothetical protein 0.0033 0.0034 0.0034
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.006 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.049 0.2165
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0265 0.0655 0.1267
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0115 0.0183
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0461 0.1182 0.8954
Schistosoma mansoni hypothetical protein 0.0035 0.0038 0.0038
Schistosoma mansoni neuronal calcium sensor 0.0115 0.0252 0.0252
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.007 0.0132 0.1
Brugia malayi calpain 7 0.0801 0.2096 0.4053
Brugia malayi 6-phosphofructokinase 0.0119 0.0263 0.0509
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0042 0.0319
Echinococcus granulosus lamin dm0 0.0083 0.0168 0.0267
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0034 0.0053
Schistosoma mansoni neuronal calcium sensor 0.0115 0.0252 0.0252
Plasmodium falciparum serine repeat antigen 4 0.0203 0.049 0.096
Giardia lamblia Cysteine protease 0.0203 0.049 0.253
Trypanosoma cruzi cysteine peptidase, putative 0.1194 0.3152 0.6094
Loa Loa (eye worm) TK/ROR protein kinase 0.013 0.0293 0.0466
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0265 0.0655 0.2078
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0992 0.2609 0.8277
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Onchocerca volvulus 0.0064 0.0115 0.037
Echinococcus multilocularis enteropeptidase 0.0057 0.0097 0.0154
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0203 0.049 0.096
Plasmodium falciparum serine repeat antigen 5 0.0203 0.049 0.096
Schistosoma mansoni intermediate filament proteins 0.0083 0.0168 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0034 0.0034
Brugia malayi Trypsin family protein 0.0057 0.0097 0.0187
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0034 0.0053
Loa Loa (eye worm) hypothetical protein 0.0036 0.0042 0.0067
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0885 0.2322 0.7368
Trypanosoma brucei cysteine peptidase, putative 0.0543 0.1403 0.4452
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0461 0.1182 0.8954
Schistosoma mansoni hypothetical protein 0.0033 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0034 0.0053
Leishmania major hypothetical protein, unknown function 0.0334 0.0842 0.2673
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0864 0.2265 1
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0485 0.1247 0.5505
Giardia lamblia Cathepsin B precursor 0.0203 0.049 0.253
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0042 0.0319
Trypanosoma brucei Calpain-like protein 1.1 0.0885 0.2322 0.7368
Echinococcus granulosus leucyl aminopeptidase 0.0077 0.015 0.0239
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.007 0.0132 0.0258
Echinococcus multilocularis thyroid hormone receptor alpha 0.0138 0.0314 0.05
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0105
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0034 0.0053
Toxoplasma gondii microneme protein, putative 0.0045 0.0066 0.0129
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0029 0.0021 0.0033
Brugia malayi Matrixin family protein 0.0041 0.0055 0.0107
Echinococcus granulosus tissue type plasminogen activator 0.012 0.0267 0.0425
Trypanosoma cruzi trypanothione reductase, putative 0.007 0.0132 0.0255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.049 0.049
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0034 0.0053
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0034 0.0053
Echinococcus granulosus bloom syndrome protein 0.0045 0.0066 0.0104
Giardia lamblia Hypothetical protein 0.0117 0.0259 0.1337
Schistosoma mansoni biogenic amine receptor 0.0033 0.0034 0.0034
Plasmodium vivax aspartyl proteinase, putative 0.0034 0.0036 0.007
Toxoplasma gondii calcium-dependent protein kinase 0.0117 0.0259 0.0507
Loa Loa (eye worm) ctsf protein 0.0864 0.2265 0.36
Loa Loa (eye worm) hypothetical protein 0.004 0.0052 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0596 0.1545 0.6824
Leishmania major protein kinase, putative 0.0115 0.0252 0.08
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0034 0.0053
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0077 0.015 0.029
Echinococcus multilocularis cathepsin b 0.1946 0.5172 0.822
Onchocerca volvulus 0.0944 0.2479 0.9325
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0203 0.049 0.049
Brugia malayi hypothetical protein 0.0039 0.005 0.0096
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0263 0.0419
Onchocerca volvulus 0.0033 0.0034 0.0061
Plasmodium vivax aspartyl proteinase, putative 0.0144 0.0331 0.0649
Schistosoma mansoni myosin light chain 0.0027 0.0018 0.0018
Schistosoma mansoni amine GPCR 0.0033 0.0034 0.0034
Brugia malayi Cathepsin L-like precursor 0.0864 0.2265 0.4379
Echinococcus granulosus chromobox protein 1 0.0072 0.0137 0.0217
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0656 0.1706 0.3299
Onchocerca volvulus 0.0057 0.0097 0.03
Giardia lamblia Cathepsin L precursor 0.0203 0.049 0.253
Entamoeba histolytica cysteine proteinase, putative 0.0471 0.121 0.5341
Trypanosoma cruzi cruzipain precursor, putative 0.1194 0.3152 0.6094
Brugia malayi PAN domain containing protein 0.0045 0.0066 0.0127
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0046
Loa Loa (eye worm) hypothetical protein 0.0081 0.0162 0.0258
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0265 0.0655 0.2078
Echinococcus granulosus EF hand domain containing family member A2 0.0117 0.0259 0.0412
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0203 0.049 0.0779
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0057 0.0097 0.0187
Onchocerca volvulus 0.0864 0.2265 0.8513
Brugia malayi AKH receptor 0.0033 0.0034 0.0065
Echinococcus granulosus programmed cell death protein 6 0.003 0.0025 0.0039
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1066 0.2807 0.8907
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0039 0.0062
Schistosoma mansoni reticulocalbin 0.0117 0.0259 0.0259
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0203 0.049 0.096
Brugia malayi cathepsin L-like cysteine proteinase 0.0203 0.049 0.0948
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0097 0.0097
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0042 0.0186
Brugia malayi Cathepsin L-like precursor 0.0864 0.2265 0.4379
Plasmodium vivax aspartyl protease, putative 0.0034 0.0036 0.007
Brugia malayi Papain family cysteine protease containing protein 0.0471 0.121 0.2339
Onchocerca volvulus 0.0115 0.0252 0.0888
Echinococcus multilocularis EF hand domain containing family member A2 0.0115 0.0252 0.0401
Loa Loa (eye worm) hypothetical protein 0.0115 0.0252 0.0401
Echinococcus multilocularis programmed cell death protein 6 0.003 0.0025 0.0039
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0203 0.049 0.096
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0385 0.0978 0.3103
Trypanosoma brucei Calpain-like protein CALP1.3 0.0543 0.1403 0.4452
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1946 0.5172 0.5172
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0209 0.0505 0.0976
Schistosoma mansoni caspase-7 (C14 family) 0.0062 0.011 0.011
Trichomonas vaginalis calcium binding protein, putative 0.0115 0.0252 0.1113
Brugia malayi cathepsin F-like cysteine proteinase 0.0203 0.049 0.0948
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0115 0.0252 0.0487
Leishmania major small myristoylated protein-1 0.036 0.0912 0.2893
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0864 0.2265 1
Echinococcus multilocularis cathepsin b 0.1946 0.5172 0.822
Trypanosoma brucei centrin, putative 0.0115 0.0252 0.08
Mycobacterium ulcerans lipase LipD 0.0036 0.0042 0.0333
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0051 0.01
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.003 0.0134
Schistosoma mansoni neuropeptide receptor 0.0033 0.0034 0.0034
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0028 0.0044
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0512 0.132 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0022 0.0034
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0334 0.0842 0.3719
Echinococcus multilocularis G-protein coupled receptor, putative 0.0033 0.0034 0.0053
Schistosoma mansoni cathepsin F (C01 family) 0.0864 0.2265 0.2265
Toxoplasma gondii EF hand domain-containing protein 0.0027 0.0018 0.0034
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0097 0.0097
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.0505 0.0976
Brugia malayi chromobox protein homolog 3 0.004 0.0052 0.0101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1194 0.3152 1
Echinococcus multilocularis G protein coupled receptor 139 0.0033 0.0034 0.0053
Brugia malayi hypothetical protein 0.0057 0.0097 0.0187
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0115 0.0252 0.0493
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0042 0.0186
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1946 0.5172 0.5172
Leishmania major cathepsin L-like protease 0.0864 0.2265 0.7186
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0036 0.0036
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0656 0.1706 0.3299
Loa Loa (eye worm) hypothetical protein 0.0054 0.009 0.0143
Loa Loa (eye worm) hypothetical protein 0.0064 0.0115 0.0183
Brugia malayi Cathepsin L-like precursor 0.0596 0.1545 0.2988
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0322 0.0623
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0034 0.0053
Leishmania major calmodulin, putative 0.0115 0.0252 0.08
Echinococcus granulosus 7TM GPCR rhodopsin 0.0033 0.0034 0.0053
Echinococcus multilocularis calmodulin 0.0115 0.0252 0.0401
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0263 0.1163
Brugia malayi Cathepsin L-like precursor 0.0268 0.0663 0.1283
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0263 0.1996
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.011 0.0175
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0336 0.0847 0.1658
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0926 0.2432 0.4703
Loa Loa (eye worm) POT family protein 0.0045 0.0064 0.0102
Trichomonas vaginalis calmodulin, putative 0.0115 0.0252 0.1113
Toxoplasma gondii centrin family protein 0.0027 0.0018 0.0034

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 3.4 uM Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK). ChEMBL. 9651163
IC50 (binding) = 3.4 uM Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK). ChEMBL. 9651163
IC50 (binding) = 44 uM Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK). ChEMBL. 9651163
IC50 (binding) = 44 uM Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK). ChEMBL. 9651163
IC50 (binding) > 100 uM Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK). ChEMBL. 9651163
IC50 (binding) > 100 uM Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK) ChEMBL. 9651163
IC50 (binding) > 100 uM Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptor ChEMBL. 9651163
IC50 (binding) > 100 uM Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK). ChEMBL. 9651163
IC50 (binding) > 100 uM Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK) ChEMBL. 9651163
IC50 (binding) > 100 uM Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptor ChEMBL. 9651163

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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