Detailed information for compound 1472737

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 352.467 | Formula: C23H28O3
  • H donors: 1 H acceptors: 2 LogP: 5.15 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(=O)c1oc2c(c1)cc1c(c2)CC[C@@H]2[C@@H]1CC[C@]1([C@H]2CC[C@@H]1O)C
  • InChi: 1S/C23H28O3/c1-3-19(24)21-12-14-10-17-13(11-20(14)26-21)4-5-16-15(17)8-9-23(2)18(16)6-7-22(23)25/h10-12,15-16,18,22,25H,3-9H2,1-2H3/t15-,16+,18-,22-,23-/m0/s1
  • InChiKey: DXMMRNKHIXQRPX-YRRUUWTKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0714 0.3424 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0025 0.0055
Onchocerca volvulus 0.0142 0.0628 0.1864
Schistosoma mansoni ste20-related kinase 0.0183 0.0831 0.0831
Mycobacterium ulcerans electron transfer protein 0.0023 0.0048 0.0104
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0545 1
Trypanosoma brucei cardiolipin synthetase 0.0037 0.0117 0.0313
Schistosoma mansoni adapter molecule crk 0.002 0.0036 0.0036
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0037 0.0117 0.2066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0104 0.0301
Schistosoma mansoni serine/threonine kinase 0.0026 0.0065 0.0065
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0106 0.0452 0.1229
Loa Loa (eye worm) hypothetical protein 0.0249 0.1153 0.1152
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0187 0.0187
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.0512 0.2191
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0065 0.0065
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0116 0.0312
Plasmodium vivax amine transporter, putative 0.0042 0.0143 0.2708
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0027 0.0066 0.0169
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0015 0.0014
Schistosoma mansoni lamin 0.0055 0.0207 0.0207
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0759 0.3642 0.3642
Echinococcus granulosus nuclear receptor nhr 48 0.0329 0.1542 0.1541
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0187 0.0187
Echinococcus granulosus MAP kinase activated protein kinase 2 0.2061 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0201 0.02
Trichomonas vaginalis glucosylceramidase, putative 0.0367 0.1728 0.5044
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0106 0.0452 0.1235
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0025 0.0063
Brugia malayi Pre-SET motif family protein 0.0216 0.099 0.0989
Echinococcus multilocularis growth factor receptor bound protein 2 0.002 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0116 0.0335
Brugia malayi G-protein coupled receptor 0.0051 0.0187 0.0187
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0162 0.3504
Onchocerca volvulus 0.0037 0.0116 0.0327
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0187 0.0187
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0177 0.0802 0.0801
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0473 0.2246 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0039 0.0127 0.0127
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0143 0.0142
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Schistosoma mansoni nuclear hormone receptor 0.0329 0.1542 0.1542
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.012 0.012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0187 0.0187
Echinococcus granulosus serine threonine protein kinase nrc 0.0028 0.0073 0.0073
Loa Loa (eye worm) AGC/AKT protein kinase 0.0051 0.0186 0.0186
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0027 0.0066 0.1135
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0106 0.0452 0.0452
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0106
Echinococcus multilocularis microtubule associated protein 2 0.1418 0.686 0.6859
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0697 0.334 0.334
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0697 0.334 1
Onchocerca volvulus 0.0051 0.0187 0.0541
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0133 0.0133
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0063 0.1016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0187 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0009 0.0009
Schistosoma mansoni adrenodoxin 0.0023 0.0048 0.0048
Brugia malayi ecdysone receptor 0.0329 0.1542 0.1541
Mycobacterium ulcerans oxygenase 0.0023 0.0048 0.0104
Leishmania major C-8 sterol isomerase-like protein 0.0759 0.3642 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0063 0.0159
Echinococcus granulosus somatostatin receptor 0.0051 0.0187 0.0187
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0047 0.0168 0.0167
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0116 0.0116
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0137 0.0137
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0545 0.0545
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0025 0.0055
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Trichomonas vaginalis glucosylceramidase, putative 0.0531 0.2527 0.7379
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0025 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0116 0.0306
Brugia malayi Pre-SET motif family protein 0.0032 0.0093 0.0092
Brugia malayi Carboxylesterase family protein 0.007 0.0277 0.0277
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0051 0.0187 0.0187
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0167
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0025 0.0063
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0697 0.334 0.334
Brugia malayi Doublecortin family protein 0.004 0.0133 0.0133
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0137 0.0369
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0019 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0356 0.1675 0.1675
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0017 0.0017 0.0016
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0187 0.0187
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0356 0.1675 0.1675
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0268 0.0724
Loa Loa (eye worm) hypothetical protein 0.0033 0.0096 0.0096
Toxoplasma gondii hypothetical protein 0.0042 0.0143 0.2548
Brugia malayi Protein kinase domain containing protein 0.0017 0.0017 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0697 0.334 0.334
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0027 0.0066 0.0066
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.0187 0.0187
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.1086 0.6843
Schistosoma mansoni RAR-like nuclear receptor 0.0697 0.334 0.334
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0039 0.0127 0.0335
Echinococcus granulosus tyrosine kinase 0.0047 0.0164 0.0163
Entamoeba histolytica hypothetical protein 0.0037 0.0116 0.2474
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0116 0.0645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0162 0.047
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0177 0.0802 0.0801
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0162 0.0432
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0023 0.0048 0.0104
Schistosoma mansoni rab6-interacting 0.004 0.0133 0.0133
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0164 0.0163
Loa Loa (eye worm) hypothetical protein 0.0697 0.334 0.334
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Brugia malayi photoreceptor-specific nuclear receptor 0.0697 0.334 0.334
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0016
Trichomonas vaginalis aldehyde oxidase, putative 0.0714 0.3424 1
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0027 0.0066 0.1367
Loa Loa (eye worm) hypothetical protein 0.0104 0.0443 0.0443
Loa Loa (eye worm) polyprenyl synthetase 0.0027 0.0066 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0201 0.02
Schistosoma mansoni polycystin 1-related 0.004 0.0133 0.0133
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.006 0.0229 0.0615
Brugia malayi larval opioid receptor 0.0051 0.0187 0.0187
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Onchocerca volvulus 0.0329 0.1542 0.4605
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0063 0.0159
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0137 0.0137
Brugia malayi Cytochrome P450 family protein 0.0058 0.0217 0.0217
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0207 0.0206
Schistosoma mansoni neuropeptide receptor 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0128 0.0128
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0019 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0039 0.0127 0.2715
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0025 0.0063
Brugia malayi intermediate filament protein 0.0055 0.0207 0.0206
Loa Loa (eye worm) carboxylesterase 0.007 0.0277 0.0277
Echinococcus granulosus dna polymerase eta 0.002 0.0033 0.0032
Echinococcus multilocularis myosin iiia 0.006 0.0229 0.0228
Brugia malayi hypothetical protein 0.0017 0.0018 0.0017
Brugia malayi Cytochrome P450 family protein 0.0018 0.0025 0.0025
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0033 0.0076
Onchocerca volvulus 0.0017 0.0017 0.003
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0337 0.1581 1
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0545 0.0545
Onchocerca volvulus 0.0051 0.0187 0.0541
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0027 0.0066 0.1576
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0033 0.0033
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0019 0.003 0.0029
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0108 0.0313
Onchocerca volvulus 0.0037 0.0116 0.0327
Schistosoma mansoni intermediate filament proteins 0.0055 0.0207 0.0207
Echinococcus multilocularis ecdysone induced protein 78C 0.0697 0.334 0.334
Brugia malayi beta-lactamase family protein 0.0037 0.0116 0.0116
Schistosoma mansoni biogenic amine receptor 0.0051 0.0187 0.0187
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0012 0.0019
Schistosoma mansoni thyroid hormone receptor 0.0697 0.334 0.334
Brugia malayi steroid hormone receptor 0.0697 0.334 0.334
Echinococcus multilocularis tumor protein p63 0.0694 0.3326 0.3326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0167
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0106 0.0452 0.1229
Brugia malayi neuropeptide F receptor 0.0051 0.0187 0.0187
Schistosoma mansoni serine/threonine-protein kinase 0.0032 0.0092 0.0092
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0015 0.0015
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0186 0.0541
Loa Loa (eye worm) variant SH3 domain-containing protein 0.002 0.0036 0.0036
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0092 0.0385 0.0385
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0116 0.0306
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0023 0.0048 0.0119
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0039 0.0127 0.0367
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0093 0.0093
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0187 0.0187
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0162 0.0162
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0023 0.0048 0.0974
Echinococcus multilocularis multidrug resistance associated protein 1 0.0014 0.0005 0.0005
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0268 0.0268
Brugia malayi Nuclear hormone receptor-like 1 0.0697 0.334 0.334
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0118 0.0512 0.1393
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Giardia lamblia MRP-like ABC transporter 0.0014 0.0005 0.0012
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0268 0.0268
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0697 0.334 0.334
Schistosoma mansoni hypothetical protein 0.0051 0.0187 0.0187
Mycobacterium leprae Probable lipase LipE 0.0037 0.0116 0.3095
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0116 0.0312
Loa Loa (eye worm) hypothetical protein 0.0041 0.0134 0.0134
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0241 0.1114 0.49
Onchocerca volvulus 0.0329 0.1542 0.4605
Brugia malayi hypothetical protein 0.0017 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0065 0.0065
Echinococcus granulosus sex peptide receptor 0.0051 0.0187 0.0187
Echinococcus granulosus intermediate filament protein 0.0055 0.0207 0.0206
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.084 0.404 0.404
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.0187 0.0187
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0027 0.0066 0.0327
Leishmania major DNA polymerase eta, putative 0.002 0.0033 0.0076
Onchocerca volvulus 0.0249 0.1153 0.3438
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0042 0.0143 0.0142
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0137 0.0137
Entamoeba histolytica protein kinase, putative 0.0034 0.01 0.2129
Brugia malayi nuclear receptor NHR-88 0.0697 0.334 0.334
Loa Loa (eye worm) AGC/PKN protein kinase 0.0026 0.0065 0.0064
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0081 0.008
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Trichomonas vaginalis glucosylceramidase, putative 0.0348 0.1636 0.4776
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0015
Brugia malayi CXXC zinc finger family protein 0.0059 0.0224 0.0224
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0027 0.0066 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Onchocerca volvulus 0.004 0.0133 0.0379
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0187 0.0187
Brugia malayi hypothetical protein 0.0454 0.2151 0.2151
Loa Loa (eye worm) hypothetical protein 0.0104 0.0442 0.0442
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0036 0.0113 0.0396
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0545 0.3387
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0116 0.0335
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0106 0.0452 0.0452
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0054 0.0201 0.02
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0116 0.041
Brugia malayi p70 ribosomal S6 kinase beta 0.0047 0.0168 0.0167
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0133 0.0133
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0487 0.893
Brugia malayi ORL1-like opioid receptor 0.0051 0.0187 0.0187
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0033 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0101 0.0101
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0798 0.3833 0.3833
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0697 0.334 0.334
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.003 0.0029
Echinococcus multilocularis lamin dm0 0.0055 0.0207 0.0206
Trichomonas vaginalis Ferredoxin 3 0.0023 0.0048 0.0137
Loa Loa (eye worm) hypothetical protein 0.0041 0.0137 0.0137
Echinococcus granulosus serotonin receptor 0.0051 0.0187 0.0187
Onchocerca volvulus 0.0042 0.0143 0.0407
Brugia malayi nuclear receptor NHR-67 0.0329 0.1542 0.1541
Loa Loa (eye worm) TK/ABL protein kinase 0.0017 0.0017 0.0016
Treponema pallidum sodium- and chloride- dependent transporter 0.0249 0.1153 1
Brugia malayi isocitrate dehydrogenase 0.0016 0.0015 0.0015
Brugia malayi G-protein coupled receptor 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0036
Echinococcus granulosus N chimaerin 0.0019 0.003 0.0029
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0015 0.0028
Schistosoma mansoni tyrosine kinase 0.0054 0.0201 0.0201
Loa Loa (eye worm) acetylcholinesterase 1 0.007 0.0277 0.0277
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0116 0.0116
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0031 0.003
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0024 0.0054 0.0054
Mycobacterium tuberculosis Conserved protein 0.0037 0.0116 0.0645
Echinococcus granulosus serine/threonine protein kinase 0.0032 0.0092 0.0091
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0063 0.1016
Schistosoma mansoni neuropeptide receptor 0.0051 0.0187 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0058 0.0166
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0025 0.0063
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0033 0.0032
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0015 0.0187
Plasmodium vivax SET domain protein, putative 0.0032 0.0093 0.1646
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0116 0.0116
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0026 0.0065 0.0064
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0015 0.0015
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0531 0.2527 0.2527
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0037 0.0403
Brugia malayi Protein kinase domain containing protein 0.0026 0.0065 0.0064
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0143 0.0143
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0137 0.0137
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0033 0.0032
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0039 0.0127 0.0335
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0143 0.0142
Toxoplasma gondii ABC1 family protein 0.0037 0.0116 0.2057
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0116 0.0306
Giardia lamblia GTOR 0.0046 0.0162 0.3276
Giardia lamblia Kinase, NEK 0.0113 0.0486 1
Loa Loa (eye worm) hypothetical protein 0.0454 0.2151 0.2151
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0106 0.0452 0.1317
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0009 0.0009
Brugia malayi ecdysteroid receptor 0.0697 0.334 0.334
Brugia malayi Dopamine receptor protein 1 0.0051 0.0187 0.0187
Entamoeba histolytica SH2-protein kinase domain containing protein 0.002 0.0033 0.0629
Trypanosoma cruzi Emopamil binding protein, putative 0.0142 0.0628 0.1714
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0137 0.0137
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0037 0.0053
Entamoeba histolytica protein kinase, putative 0.0051 0.0186 0.4042
Echinococcus granulosus g-protein coupled receptor 0.0051 0.0187 0.0187
Leishmania major cytochrome p450-like protein 0.0018 0.0025 0.0055
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0009
Brugia malayi RhoGAP domain containing protein 0.0019 0.003 0.0029
Onchocerca volvulus 0.0055 0.0207 0.0599
Entamoeba histolytica protein kinase, putative 0.0026 0.0065 0.1331
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0093 0.0092
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Brugia malayi GnHR receptor homolog 0.0051 0.0187 0.0187
Brugia malayi Hr1 repeat family protein 0.0026 0.0065 0.0064
Brugia malayi Polyprenyl synthetase family protein 0.0027 0.0066 0.0066
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0093 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Onchocerca volvulus 0.0051 0.0187 0.0541
Schistosoma mansoni biogenic amine receptor 0.0051 0.0187 0.0187
Brugia malayi Steroid receptor seven-up type 2 0.0697 0.334 0.334
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0116 0.2145
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.0187 0.0187
Giardia lamblia Multidrug resistance-associated protein 1 0.0014 0.0005 0.0012
Schistosoma mansoni lipoxygenase 0.0105 0.0447 0.0447
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0187 0.0187
Echinococcus granulosus fmrfamide receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis conserved hypothetical protein 0.0711 0.3409 0.3408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0104 0.0301
Onchocerca volvulus 0.0051 0.0187 0.0541
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0015 0.0028
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Schistosoma mansoni nuclear receptor 0.0329 0.1542 0.1542
Echinococcus granulosus tm gpcr rhodopsin 0.0905 0.4354 0.4354
Echinococcus multilocularis nervana 2 0.0021 0.0039 0.0039
Echinococcus granulosus acetylcholinesterase 0.007 0.0277 0.0277
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0329 0.1542 0.1541
Trichomonas vaginalis Ferredoxin 7 0.0023 0.0048 0.0137
Echinococcus multilocularis FTZ F1 alpha 0.0697 0.334 0.334
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.0051 0.0187 0.0187
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0025 0.0063
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0187 0.0187
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0137 0.0137
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0143 0.0142
Giardia lamblia Multidrug resistance-associated protein 1 0.0014 0.0005 0.0012
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0714 0.3424 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.0187 0.0187
Echinococcus granulosus neuropeptide receptor 0.0051 0.0187 0.0187
Leishmania major hypothetical protein, conserved 0.0037 0.0116 0.0306
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0019 0.003 0.0029
Echinococcus granulosus FTZ F1 alpha 0.0697 0.334 0.334
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0368 0.1734 0.1734
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0017 0.0019 0.0045
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Brugia malayi nuclear hormone receptor 0.0329 0.1542 0.1541
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0697 0.334 0.334
Schistosoma mansoni multidrug resistance protein 0.0014 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0187 0.0187
Toxoplasma gondii ferredoxin, putative 0.0023 0.0048 0.08
Leishmania major cardiolipin synthetase, putative 0.0017 0.0019 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0116 0.0335
Onchocerca volvulus 0.0697 0.334 1
Brugia malayi Uncoordinated protein 44 0.0015 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0697 0.334 0.334
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.0065 0.0064
Echinococcus granulosus growth factor receptor bound protein 2 0.002 0.0036 0.0036
Echinococcus multilocularis nuclear receptor nhr 48 0.0329 0.1542 0.1541
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0697 0.334 0.334
Onchocerca volvulus 0.0051 0.0187 0.0541
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0015 0.0014
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0015
Onchocerca volvulus Protein ultraspiracle homolog 0.0697 0.334 1
Loa Loa (eye worm) CYP4Cod1 0.0036 0.0113 0.0112
Echinococcus multilocularis protein kinase c iota type 0.0033 0.0095 0.0095
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.0187 0.0541
Echinococcus granulosus nervana 2 0.0021 0.0039 0.0039
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0042 0.0143 0.0142
Schistosoma mansoni neuropeptide receptor 0.0051 0.0187 0.0187
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0137 0.0137
Echinococcus multilocularis cpg binding protein 0.0062 0.0241 0.024
Brugia malayi SRC-1 0.0054 0.0201 0.02
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0033 0.0032
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0116 0.0645
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.006 0.0229 0.0621
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Onchocerca volvulus Glucosylceramidase homolog 0.0348 0.1636 0.4888
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0187 0.0187
Onchocerca volvulus 0.004 0.0133 0.0379
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0089 0.0371 0.8153
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0187 0.0187
Schistosoma mansoni nuclear hormone receptor 0.0329 0.1542 0.1542
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0368 0.1734 0.1734
Mycobacterium ulcerans hypothetical protein 0.0021 0.0037 0.0053
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0033 0.0034
Brugia malayi Protein kinase domain containing protein 0.0017 0.0017 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0025 0.0063
Loa Loa (eye worm) hypothetical protein 0.0368 0.1734 0.1734
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0143 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0104 0.0301
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0143 0.0143
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0187 0.0187
Schistosoma mansoni growth factor receptor-bound protein 0.002 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0078 0.0319 0.0319
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0697 0.334 0.334
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0187 0.0187
Echinococcus granulosus acetylcholinesterase 0.007 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0388 0.183 0.183
Brugia malayi nuclear receptor RXR 0.0329 0.1542 0.1541
Trypanosoma cruzi cardiolipin synthetase, putative 0.0037 0.0117 0.0307
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0187 0.0187
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0186 0.0541
Onchocerca volvulus 0.0104 0.0442 0.1307
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0027 0.0066 0.0066
Giardia lamblia Kinase, STE STE20 0.006 0.0229 0.4654
Schistosoma mansoni tyrosine kinase 0.0054 0.0201 0.0201
Trypanosoma brucei cardiolipin synthetase, putative 0.0037 0.0117 0.0313
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0026 0.0065 0.0064
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.0187 0.0187
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0012 0.0019
Brugia malayi Protein kinase domain containing protein 0.0017 0.0017 0.0016
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0026 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Loa Loa (eye worm) hypothetical protein 0.0368 0.1734 0.1734
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0137 0.0397
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0187 0.0187
Schistosoma mansoni cellular tumor antigen P53 0.0102 0.0432 0.0432
Echinococcus multilocularis c src tyrosine kinase 0.0024 0.0054 0.0053
Echinococcus multilocularis 0.0018 0.0025 0.0025
Schistosoma mansoni adenoreceptor 0.0051 0.0187 0.0187
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0106 0.0452 0.928
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.0187 0.0187
Echinococcus granulosus ecdysone induced protein 78C 0.0697 0.334 0.334
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Mycobacterium ulcerans beta-lactamase 0.0037 0.0116 0.041
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0143 0.0142
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Echinococcus multilocularis serine threonine protein kinase 0.0068 0.0269 0.0269
Brugia malayi Nuclear hormone receptor E75 0.0329 0.1542 0.1541
Brugia malayi hypothetical protein 0.0329 0.1542 0.1541
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0058 0.0166
Onchocerca volvulus 0.0037 0.0116 0.0327
Echinococcus multilocularis sex peptide receptor 0.0051 0.0187 0.0187
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0368 0.1734 0.1734
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0039 0.0127 0.2373
Loa Loa (eye worm) steroid hormone receptor 0.0697 0.334 0.334
Brugia malayi Protein kinase domain containing protein 0.0179 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0033 0.0076
Brugia malayi Polyprenyl synthetase family protein 0.0106 0.0452 0.0452
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0697 0.334 0.334
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0015 0.0015
Treponema pallidum quinoline 2-oxidoreductase 0.0113 0.049 0.3898
Echinococcus granulosus orexin receptor type 2 0.0051 0.0187 0.0187
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0048 0.0119
Echinococcus multilocularis rac serine:threonine kinase 0.0032 0.0092 0.0091
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0143 0.0142
Brugia malayi Phospholipase d protein 1 0.0106 0.0454 0.0453
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0019 0.0031 0.0086
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0116 0.0645
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.0187 0.0187
Plasmodium vivax ferredoxin, putative 0.0023 0.0048 0.0703
Plasmodium falciparum amino acid transporter, putative 0.0042 0.0143 0.2708
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0129 0.0373
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0092 0.1933
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0023 0.0048 0.0048
Echinococcus multilocularis Ankyrin 0.0015 0.0009 0.0009
Brugia malayi Nuclear hormone receptor-like 1 0.0368 0.1734 0.1734
Brugia malayi conserved hypotetical protein 0.0329 0.1542 0.1541
Loa Loa (eye worm) hypothetical protein 0.0037 0.0116 0.0116
Brugia malayi Dopamine receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0025 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0697 0.334 0.334
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.043 0.2035 0.2034
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0142 0.0628 0.1714
Brugia malayi Protein kinase domain containing protein 0.0017 0.0017 0.0016
Schistosoma mansoni nuclear receptor nhr-48 0.0329 0.1542 0.1542
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0356 0.1675 0.1675
Toxoplasma gondii endonuclease IV APN 0.0078 0.0319 0.5819
Brugia malayi Protein kinase c protein 2 0.0055 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0249 0.1153 0.1152
Loa Loa (eye worm) beta-lactamase 0.0037 0.0116 0.0116
Loa Loa (eye worm) nuclear receptor NHR-67 0.0329 0.1542 0.1541
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0012 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0116 0.0335
Trichomonas vaginalis STE family protein kinase 0.006 0.0229 0.0664
Mycobacterium tuberculosis Conserved protein 0.0037 0.0116 0.0645
Brugia malayi Death domain containing protein 0.0015 0.0008 0.0008
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0081 0.0081
Giardia lamblia Kinase, NEK 0.0113 0.0486 1
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Schistosoma mansoni sodium-dependent amino acid transporter 0.0042 0.0143 0.0143
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0025 0.0063
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0162 0.0162
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0116 0.0645
Echinococcus granulosus phospholipase D1 0.0106 0.0454 0.0453
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0104 0.0301
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0015 0.0034
Leishmania major hypothetical protein, conserved 0.0026 0.0063 0.0159
Treponema pallidum hypothetical protein 0.0096 0.0403 0.3099
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0143 0.2548
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0054 0.0201 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0162 0.047
Brugia malayi nuclear receptor RXR 0.0368 0.1734 0.1734
Brugia malayi G protein-coupled receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0697 0.334 0.334
Echinococcus multilocularis nervana 2 0.0021 0.0039 0.0039
Schistosoma mansoni neuropeptide receptor 0.0051 0.0187 0.0187
Brugia malayi AKH receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0905 0.4354 0.4354
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0023
Schistosoma mansoni multidrug resistance protein 0.0014 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0054 0.0201 0.02
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0054 0.0201 0.02
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0187 0.0187
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.0187 0.0187
Brugia malayi ABC transporter transmembrane region family protein 0.0014 0.0005 0.0005
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.0187 0.0187
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0012 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0204
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0137 0.0137
Onchocerca volvulus 0.0055 0.0207 0.0599
Echinococcus multilocularis Glutaredoxin protein 5 0.0021 0.0039 0.0039
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0023 0.0048 0.0125
Echinococcus multilocularis NCK adaptor protein 0.002 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Echinococcus multilocularis tyrosine protein kinase HCK 0.0034 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0048 0.0119
Echinococcus multilocularis serotonin receptor 0.0051 0.0187 0.0187
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0241 0.1114 0.49
Echinococcus multilocularis lamin 0.0055 0.0207 0.0206
Schistosoma mansoni glutathione synthetase 0.0027 0.0066 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0585 0.2792 0.2791
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0033 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0697 0.334 0.334
Echinococcus multilocularis somatostatin receptor 0.0051 0.0187 0.0187
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0186 0.0541
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0133 0.0133
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0118 0.0512 0.0511
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.0187 0.0187
Giardia lamblia Kinase, AGC PKA 0.0028 0.0073 0.1427
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0042 0.0143 0.0142
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0015 0.0034
Echinococcus granulosus tyrosine protein kinase ABL1 0.0017 0.0017 0.0016
Giardia lamblia Farnesyl diphosphate synthase 0.0106 0.0452 0.9296
Loa Loa (eye worm) hypothetical protein 0.0089 0.0371 0.037
Echinococcus multilocularis N chimaerin 0.0019 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0036
Schistosoma mansoni hypothetical protein 0.0051 0.0187 0.0187
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0142 0.0628 0.1714
Schistosoma mansoni cpg binding protein 0.0062 0.0241 0.0241
Entamoeba histolytica protein kinase 2, putative 0.0028 0.0073 0.1519
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0128 0.0128
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0136 0.0602 0.2597
Trichomonas vaginalis AGC family protein kinase 0.003 0.0083 0.0239
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0032 0.0093 0.0092
Schistosoma mansoni biogenic amine receptor 0.0051 0.0187 0.0187
Schistosoma mansoni steroid hormone receptor ad4bp 0.0697 0.334 0.334
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0106 0.0452 0.1317
Loa Loa (eye worm) hypothetical protein 0.0089 0.0371 0.037
Echinococcus multilocularis phospholipase D1 0.0106 0.0454 0.0453
Leishmania major cytochrome p450-like protein 0.0036 0.0113 0.0297
Echinococcus granulosus tyrosine kinase 0.0017 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0015 0.0014
Echinococcus multilocularis dna polymerase eta 0.002 0.0033 0.0032
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0019 0.003 0.003
Onchocerca volvulus 0.0051 0.0187 0.0541
Trichomonas vaginalis glucosylceramidase, putative 0.0367 0.1728 0.5044
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0012 0.0011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0697 0.334 0.334
Echinococcus granulosus tachykinin peptides receptor 99D 0.0051 0.0187 0.0187
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0027 0.0066 0.1403
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Brugia malayi neuropeptide F receptor 0.0051 0.0187 0.0187
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0106 0.0452 0.1923
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0106 0.0452 0.928
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0162 0.0162
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.0187 0.0187
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0106 0.0452 0.2792
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.006 0.0229 0.4983
Echinococcus granulosus phospholipase d3 0.002 0.0034 0.0033
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0116 0.3095
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.0187 0.0187
Echinococcus granulosus hypothetical protein 0.0763 0.366 0.366
Brugia malayi Tyrosine-protein kinase abl-1 0.0024 0.0054 0.0053
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.002 0.0036 0.0036
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0545 0.0545
Echinococcus granulosus death domain containing protein 0.0015 0.0008 0.0008
Echinococcus granulosus dna polymerase kappa 0.002 0.0033 0.0032
Plasmodium vivax cardiolipin synthetase, putative 0.0017 0.0019 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0697 0.334 0.334
Trypanosoma brucei electron transfer protein, putative 0.0023 0.0048 0.0125
Loa Loa (eye worm) hypothetical protein 0.0102 0.0432 0.0432
Echinococcus multilocularis multidrug resistance associated protein 7 0.0014 0.0005 0.0005
Onchocerca volvulus 0.0017 0.0017 0.003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0031 0.003
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0051 0.0187 0.0187
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0697 0.334 0.334
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.0187 0.0187
Brugia malayi Variant SH3 domain containing protein 0.0019 0.003 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0348 0.1636 0.4776
Schistosoma mansoni rab6-interacting 0.004 0.0133 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.007 0.02
Trypanosoma brucei p-glycoprotein 0.0014 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0037 0.0116 0.0116
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0486 0.1416
Echinococcus granulosus tyrosine protein kinase Blk 0.0047 0.0164 0.0163
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Echinococcus granulosus neuropeptide receptor A26 0.0523 0.2488 0.2487
Schistosoma mansoni hypothetical protein 0.0053 0.0196 0.0196
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0015 0.0015
Brugia malayi Sex muscle abnormal protein 5 0.002 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0081 0.0081
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Echinococcus granulosus tyrosine protein kinase Lyn 0.0061 0.0235 0.0234
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0143 0.0142
Loa Loa (eye worm) hypothetical protein 0.0027 0.0067 0.0066
Echinococcus multilocularis phospholipase d3 0.002 0.0034 0.0033
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0697 0.334 0.334
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0137 0.0363
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0063 0.0166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0058 0.0166
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0028 0.0073 0.1233
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.0187 0.0187
Brugia malayi M-phase phosphoprotein, mpp8 0.0104 0.0442 0.0442
Trypanosoma brucei C-8 sterol isomerase, putative 0.0759 0.3642 1
Brugia malayi orphan nuclear receptor NR2E1 0.0329 0.1542 0.1541
Brugia malayi hypothetical protein 0.0026 0.0063 0.0062
Trichomonas vaginalis Ferredoxin 2 0.0023 0.0048 0.0137
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0697 0.334 0.334
Brugia malayi hypothetical protein 0.0017 0.0017 0.0016
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0013 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0186 0.0541
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0143 0.0142
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0116 0.0116
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0143 0.0142
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0027 0.0066 0.1367
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0113 0.0297
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0008 0.0008
Echinococcus granulosus Nuclear hormone receptor HR96 0.0329 0.1542 0.1541
Toxoplasma gondii AGC kinase 0.0047 0.0168 0.3013
Leishmania major protein kinase, putative 0.006 0.0229 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0104 0.0301
Loa Loa (eye worm) hypothetical protein 0.0697 0.334 0.334
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0187 0.0187
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0329 0.1542 0.1542
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0026 0.0065 0.0064
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0116 0.0306
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Loa Loa (eye worm) DR-78 0.0329 0.1542 0.1541
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0025 0.0063
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0268 0.073
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0116 0.0116
Echinococcus granulosus tyrosine protein kinase Src64B 0.0054 0.0201 0.02
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0039 0.0127 0.0126
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0025 0.0061
Loa Loa (eye worm) hypothetical protein 0.0042 0.0143 0.0142
Loa Loa (eye worm) solute carrier family 6 member 4 0.0249 0.1153 0.1152
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0116 0.0116
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0697 0.334 0.334
Brugia malayi Melatonin receptor type 1A 0.0051 0.0187 0.0187
Schistosoma mansoni zinc finger protein 0.0329 0.1542 0.1542
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0187 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0015 0.0014
Brugia malayi Nuclear hormone receptor E75 0.0329 0.1542 0.1541
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0031 0.003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0013 0.0013
Loa Loa (eye worm) cytochrome P450 0.0018 0.0025 0.0025
Echinococcus multilocularis musashi 0.0055 0.0207 0.0206
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0116 0.0645
Schistosoma mansoni multidrug resistance protein 0.0014 0.0005 0.0005
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0027 0.0066 0.0175
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0167
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0025 0.0063
Plasmodium falciparum NIMA related kinase 1 0.0113 0.0486 1
Brugia malayi Carboxylesterase family protein 0.007 0.0277 0.0277
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0027 0.0066 0.0327
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0033 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0025 0.0063
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0014 0.0005 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0058 0.0166
Echinococcus granulosus g protein coupled receptor 0.0051 0.0187 0.0187
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0162 0.0432
Echinococcus granulosus lamin dm0 0.0055 0.0207 0.0206
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0015 0.0015
Brugia malayi multidrug resistance related protein 1 0.0014 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0031
Onchocerca volvulus 0.0051 0.0187 0.0541
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0025 0.0371
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0143 0.0142
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.0187 0.0187
Trypanosoma brucei unspecified product 0.002 0.0033 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0065 0.0185
Schistosoma mansoni hypothetical protein 0.0037 0.0116 0.0116
Echinococcus granulosus Ankyrin 0.0015 0.0009 0.0009
Entamoeba histolytica protein kinase, putative 0.002 0.0033 0.0629
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0027 0.0066 0.0186
Brugia malayi Protein kinase domain containing protein 0.0026 0.0065 0.0064
Schistosoma mansoni nck2/grb4 0.002 0.0036 0.0036
Schistosoma mansoni cpg binding protein 0.0059 0.0224 0.0224
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.0187 0.0187
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0104 0.1838
Loa Loa (eye worm) hypothetical protein 0.0054 0.0202 0.0201
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.0187 0.0187
Brugia malayi Variant SH3 domain containing protein 0.002 0.0036 0.0036
Schistosoma mansoni coup transcription factor 0.0697 0.334 0.334
Mycobacterium ulcerans lipase LipD 0.0037 0.0116 0.041
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.015 0.015
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0143 0.2708
Echinococcus granulosus Adrenodoxin mitochondrial 0.0023 0.0048 0.0048
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0025 0.0025
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0187 0.0187
Brugia malayi Cytochrome P450 family protein 0.0036 0.0113 0.0112
Loa Loa (eye worm) SRC-1 0.0054 0.0201 0.02
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0187 0.0187
Trypanosoma brucei Emopamil binding protein, putative 0.0142 0.0628 0.1719
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0025 0.0063
Loa Loa (eye worm) doublecortin family protein 0.004 0.0133 0.0133
Toxoplasma gondii hypothetical protein 0.0042 0.0143 0.2548
Giardia lamblia Kinase, NEK 0.0113 0.0486 1
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0319 0.646
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Brugia malayi hypothetical protein 0.0037 0.0116 0.0116
Echinococcus granulosus serine:threonine protein kinase 3 0.0236 0.109 0.1089
Echinococcus multilocularis protein kinase c epsilon type 0.0034 0.0101 0.0101
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0307 0.0306
Brugia malayi SET domain containing protein 0.0014 0.0005 0.0004
Brugia malayi Protein kinase domain containing protein 0.0051 0.0186 0.0186
Brugia malayi SH2 domain containing protein 0.0017 0.0017 0.0016
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0116 0.0335
Schistosoma mansoni nuclear hormone receptor 0.0697 0.334 0.334
Leishmania major solanesyl-diphosphate synthase, putative 0.0027 0.0066 0.0169
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0249 0.1153 0.1153
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0093 0.0092
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0027 0.0066 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0061
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0249 0.1153 0.1152
Brugia malayi SH2 domain containing protein 0.0017 0.0017 0.0016
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0759 0.3642 1
Echinococcus multilocularis serotonin transporter 0.0249 0.1153 0.1152
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0136 0.0602 0.3749
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.012 0.012
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0025 0.0063
Chlamydia trachomatis ferredoxin 0.0023 0.0048 0.0974
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0042 0.0143 0.4117
Echinococcus multilocularis RUN 0.004 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Onchocerca volvulus 0.0454 0.2151 0.6433
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0187 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0031
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0027 0.0066 1
Leishmania major hypothetical protein, conserved 0.0023 0.0048 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0083 0.0238
Loa Loa (eye worm) AGC/NDR protein kinase 0.0026 0.0065 0.0064
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.0187 0.0187
Entamoeba histolytica phospholipase D, putative 0.0106 0.0454 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0116 0.0645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0031
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0162 0.3504
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0023 0.0048 0.0212
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0033 0.0033
Echinococcus granulosus allatostatin A receptor 0.0051 0.0187 0.0187
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0106 0.0452 0.8277
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0025 0.0055
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0042 0.0143 0.0142
Brugia malayi tailless protein 0.0329 0.1542 0.1541
Schistosoma mansoni tyrosine kinase 0.0024 0.0054 0.0054
Echinococcus granulosus ferredoxin 0.0023 0.0048 0.0048
Echinococcus granulosus neuropeptide receptor 0.0051 0.0187 0.0187
Schistosoma mansoni nuclear receptor 0.0329 0.1542 0.1542
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0116 0.0116
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0039 0.0127 0.0126
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0187 0.0187
Leishmania major cytochrome p450-like protein 0.0018 0.0025 0.0055
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.012 0.012
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.0319 0.1944
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.0064
Brugia malayi hypothetical protein 0.004 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0027 0.0066 0.0327
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0062
Schistosoma mansoni amine GPCR 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0033 0.0082
Schistosoma mansoni amine GPCR 0.0393 0.1854 0.1854
Treponema pallidum hypothetical protein 0.0116 0.0503 0.4019
Trichomonas vaginalis glucosylceramidase, putative 0.0348 0.1636 0.4776
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0337 0.1581 0.7002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0697 0.334 0.334
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0329 0.1542 0.1541
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0201 0.02
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0545 0.2342
Onchocerca volvulus 0.0051 0.0187 0.0541
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0033 0.0076
Loa Loa (eye worm) hypothetical protein 0.0037 0.0116 0.0116
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0015 0.0015
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0697 0.334 0.334
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0092 0.0385 0.0385
Schistosoma mansoni hypothetical protein 0.0051 0.0187 0.0187
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0039 0.0127 0.0126
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0027 0.0066 0.0169
Giardia lamblia [2Fe-2S] ferredoxin 0.0023 0.0048 0.0909
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0015 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0697 0.334 0.334
Onchocerca volvulus 0.0017 0.0017 0.003
Schistosoma mansoni retinoic acid receptor RXR 0.0798 0.3833 0.3833
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0337 0.1581 0.7002
Echinococcus granulosus NDR protein kinase 0.0026 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0037 0.0116 0.0116
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0023 0.0048 0.0119
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0025 0.0063
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0092 0.1933
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0108 0.0313
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0187 0.0187
Brugia malayi RE15519p 0.0051 0.0187 0.0187
Echinococcus multilocularis dna polymerase kappa 0.002 0.0033 0.0032
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0051 0.0187 0.0187
Entamoeba histolytica protein kinase, putative 0.0047 0.0168 0.3628
Schistosoma mansoni lamin 0.0055 0.0207 0.0207
Echinococcus granulosus geminin 0.0174 0.0783 0.0783
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0268 0.0268
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0697 0.334 0.334
Leishmania major polyprenyl synthase, putative 0.0027 0.0066 0.0169
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0186 0.0541
Loa Loa (eye worm) hypothetical protein 0.0368 0.1734 0.1734
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0207 0.0206
Trypanosoma cruzi polyprenyl synthase, putative 0.0027 0.0066 0.0169
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0027 0.0066 0.1367
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0133 0.0133
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0048 0.0119
Onchocerca volvulus 0.0051 0.0187 0.0541
Onchocerca volvulus 0.0017 0.0017 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0065 0.0065
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0012 0.0011
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0033 0.0076
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0143 0.2548
Brugia malayi Cytochrome P450 family protein 0.0036 0.0113 0.0112
Echinococcus granulosus multidrug resistance associated protein 7 0.0014 0.0005 0.0005
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.0035 0.0106 0.0106
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0033 0.0076
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0026 0.0065 0.0064
Schistosoma mansoni phospholipase D 0.0106 0.0454 0.0454
Echinococcus multilocularis serine:threonine protein kinase 3 0.0236 0.109 0.1089
Brugia malayi Protein kinase domain containing protein 0.0017 0.0017 0.0016
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0025 0.0063
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0759 0.3642 0.3642
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0187 0.0187
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0113 0.0486 0.8904
Trichomonas vaginalis glucosylceramidase, putative 0.0531 0.2527 0.7379
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0021 0.0039 0.0039
Schistosoma mansoni amine GPCR 0.0051 0.0187 0.0187
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0307 0.0306
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0143 0.2548
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0133 0.2509
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0041 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0697 0.334 0.334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0058 0.0166
Schistosoma mansoni amine GPCR 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0162 0.047
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0039 0.0127 0.2255
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0136 0.0602 0.2597
Loa Loa (eye worm) hypothetical protein 0.0356 0.1675 0.1675
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0042 0.0143 0.0142
Echinococcus granulosus tyrosine protein kinase Srms 0.0017 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0104 0.0301
Loa Loa (eye worm) TK protein kinase 0.0034 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0697 0.334 0.334
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0224 0.0224
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0185 0.0185
Leishmania major ferredoxin 2fe-2s-like protein 0.0023 0.0048 0.0119
Loa Loa (eye worm) nuclear hormone receptor 0.0329 0.1542 0.1541
Brugia malayi sulfakinin receptor protein 0.0051 0.0187 0.0187
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0329 0.1542 0.1541
Onchocerca volvulus 0.0023 0.0048 0.0124
Onchocerca volvulus 0.0042 0.0143 0.0407
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0106 0.0452 0.0452
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0241 0.1114 0.7017
Onchocerca volvulus 0.0051 0.0187 0.0541
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0026 0.0065 0.0064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0167
Leishmania major hypothetical protein, conserved 0.0142 0.0628 0.1714
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0185 0.0185
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0093 0.0093
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0113 0.0297
Schistosoma mansoni lipoxygenase 0.0177 0.0802 0.0802
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0106 0.0452 0.1317
Schistosoma mansoni tyrosine kinase 0.0017 0.0017 0.0017
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0015 0.0028
Echinococcus granulosus multidrug resistance associated protein 1 0.0014 0.0005 0.0005
Onchocerca volvulus Bile acid receptor homolog 0.0697 0.334 1
Brugia malayi hypothetical protein 0.0104 0.0443 0.0443
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0058 0.0166
Echinococcus granulosus GPCR family 2 0.0016 0.0015 0.0014
Trypanosoma cruzi polyprenyl synthase, putative 0.0027 0.0066 0.0169
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0329 0.1542 0.1541
Brugia malayi Phospholipase D. Active site motif family protein 0.002 0.0034 0.0033
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0137 0.0137
Onchocerca volvulus 0.0246 0.1135 0.3384
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0118 0.0512 0.0512
Trypanosoma brucei rac serine-threonine kinase, putative 0.0051 0.0186 0.0505
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0368 0.1734 0.1734
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0204
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0545 0.0545
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0277 0.0277
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0329 0.1542 0.1541
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.006 0.0229 0.4983
Schistosoma mansoni growth factor receptor-bound protein 0.002 0.0036 0.0036
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0033 0.0032
Mycobacterium tuberculosis Possible oxygenase 0.0023 0.0048 0.0212
Brugia malayi hypothetical protein 0.0329 0.1542 0.1541
Brugia malayi nuclear hormone receptor 0.0697 0.334 0.334
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0187 0.0187
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0187 0.0187
Brugia malayi nuclear hormone receptor family member nhr-6 0.0329 0.1542 0.1541
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0118 0.0512 0.3172
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0697 0.334 0.334
Echinococcus granulosus NCK adaptor protein 0.002 0.0036 0.0036
Brugia malayi putative neuropeptide receptor 0.0051 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0015
Trichomonas vaginalis Ferredoxin 1 0.0023 0.0048 0.0137
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0039 0.0127 0.0335
Echinococcus granulosus tyrosine protein kinase HCK 0.0034 0.01 0.01
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0015 0.0015
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0319 0.646
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0187 0.0187
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0023 0.0064
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.0187 0.0187
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0033 0.0112
Loa Loa (eye worm) hypothetical protein 0.0368 0.1734 0.1734
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Echinococcus multilocularis neuropeptide s receptor 0.0523 0.2488 0.2487
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0013 0.0013
Onchocerca volvulus 0.0051 0.0187 0.0541
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0088 0.0252
Echinococcus granulosus Glutaredoxin protein 5 0.0021 0.0039 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0348 0.1636 0.4776
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0023 0.0048 0.0212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0116 0.0335
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0023 0.0048 0.0048
Brugia malayi Variant SH3 domain containing protein 0.002 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0454 0.2151 0.2151
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0027 0.0066 0.0186
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0697 0.334 0.334
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0113 0.0486 1
Mycobacterium ulcerans hypothetical protein 0.0037 0.0116 0.041
Schistosoma mansoni microtubule-associated protein tau 0.1418 0.686 0.686
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0025 0.0063
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0092 0.0385 0.0385
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.0187 0.0187
Trypanosoma cruzi cardiolipin synthetase, putative 0.0037 0.0117 0.0307
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0065 0.0185
Loa Loa (eye worm) hypothetical protein 0.0368 0.1734 0.1734
Onchocerca volvulus 0.0017 0.0017 0.003
Brugia malayi Nuclear hormone receptor-like 1 0.0368 0.1734 0.1734
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0187 0.0187
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0106 0.0452 0.1923
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0137 0.0397
Onchocerca volvulus 0.0042 0.0143 0.0407
Loa Loa (eye worm) hypothetical protein 0.007 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0162 0.0432
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0063 0.1016
Schistosoma mansoni atypical protein kinase C 0.0033 0.0095 0.0095
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0201 0.02
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0187 0.0187
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0067 0.0066
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0048 0.0212
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0143 0.0143
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0023 0.0048 0.0124
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0049 0.0175 0.0174
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0137 0.2755
Echinococcus granulosus Nuclear hormone receptor HR96 0.0329 0.1542 0.1541
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Brugia malayi hypothetical protein 0.0042 0.0143 0.0142
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0017 0.0017 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0697 0.334 0.334
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0133 0.0133
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0137 0.0363
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.03 0.03
Echinococcus multilocularis orexin receptor type 2 0.0051 0.0187 0.0187
Schistosoma mansoni myosin xvIII 0.0051 0.0187 0.0187
Trichomonas vaginalis glucosylceramidase, putative 0.0531 0.2527 0.7379
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0043 0.0111
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0187 0.0187
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0116 0.0116
Brugia malayi hypothetical protein 0.0368 0.1734 0.1734
Entamoeba histolytica hypothetical protein 0.0037 0.0116 0.2474
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0329 0.1542 0.1541
Mycobacterium ulcerans hypothetical protein 0.0116 0.0503 0.2152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0058 0.0166
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0217 0.0217
Echinococcus granulosus tyrosine protein kinase Src42A 0.0054 0.0201 0.02
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0033 0.0091
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0142 0.0628 0.1714
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0143 0.0142
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0017 0.0017 0.0266
Onchocerca volvulus 0.0051 0.0187 0.0541
Schistosoma mansoni histamine h1 receptor 0.0051 0.0187 0.0187
Mycobacterium ulcerans oxidoreductase 0.0023 0.0048 0.0104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Echinococcus multilocularis serotonin receptor 0.0051 0.0187 0.0187
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.2061 1 1
Brugia malayi nuclear receptor NHR-88 0.0329 0.1542 0.1541
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0012 0.0019
Trichomonas vaginalis Ferredoxin 6 0.0023 0.0048 0.0137
Echinococcus multilocularis tyrosine protein kinase Blk 0.0047 0.0164 0.0163
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.0319 0.0319
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.0187 0.0187
Trichomonas vaginalis glucosylceramidase, putative 0.0531 0.2527 0.7379
Schistosoma mansoni vav2 0.0023 0.0048 0.0048
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0187 0.0187
Schistosoma mansoni multidrug resistance protein 0.0014 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0697 0.334 0.334
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0329 0.1542 0.4605
Entamoeba histolytica hypothetical protein 0.0015 0.0011 0.0137
Schistosoma mansoni hypothetical protein 0.0174 0.0783 0.0783
Loa Loa (eye worm) hypothetical protein 0.0047 0.0165 0.0164
Brugia malayi follicle stimulating hormone receptor 0.0051 0.0187 0.0187
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.0187 0.0187
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.007 0.0277 0.0277
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0034 0.0101 0.0101
Echinococcus granulosus carboxylesterase 5A 0.007 0.0277 0.0277
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0013 0.0013
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.0187 0.0187
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0033 0.0082
Echinococcus granulosus neuropeptide s receptor 0.0523 0.2488 0.2487
Loa Loa (eye worm) polyprenyl synthetase 0.0106 0.0452 0.0452
Schistosoma mansoni opsin-like receptor 0.0051 0.0187 0.0187
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0027 0.0066 0.0169
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0162 0.0439
Brugia malayi beta-lactamase family protein 0.0037 0.0116 0.0116
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.0187 0.0187
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.0187 0.0187
Schistosoma mansoni DNA polymerase eta 0.002 0.0033 0.0033
Onchocerca volvulus 0.0044 0.015 0.0428
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0063 0.1072
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0037 0.0036
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0143 0.0143
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0009 0.0009
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0137 0.0137
Onchocerca volvulus 0.0051 0.0187 0.0541
Loa Loa (eye worm) hypothetical protein 0.0697 0.334 0.334
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0137 0.0397
Echinococcus granulosus microtubule associated protein 2 0.1418 0.686 0.6859
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Onchocerca volvulus 0.0059 0.0224 0.0652
Echinococcus multilocularis RNA directed DNA polymerase 0.0041 0.0134 0.0134
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0069 0.0273 0.0273
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0187 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.2061 1 1
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0187 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Mycobacterium ulcerans epimerase 0.0021 0.0037 0.0053
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0054 0.0201 0.02
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0026 0.0065 0.0064
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0187 0.0187
Onchocerca volvulus 0.0102 0.0432 0.1276
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.003 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0116 0.0335
Chlamydia trachomatis endonuclease IV 0.0078 0.0319 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0545 0.2342
Brugia malayi CHD4 protein 0.0015 0.0009 0.0009
Echinococcus granulosus RNA directed DNA polymerase 0.0041 0.0134 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0697 0.334 0.334
Echinococcus granulosus protein kinase C gamma type 0.0068 0.0269 0.0269
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0697 0.334 0.334
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0249 0.1153 0.1152
Plasmodium falciparum ferredoxin, putative 0.0023 0.0048 0.0703
Echinococcus granulosus serine:threonine protein kinase N2 0.0026 0.0065 0.0064
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0329 0.1542 0.1541
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.0187 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0042 0.0143 0.0142
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0054 0.0201 0.02
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Echinococcus multilocularis tyrosine protein kinase Abl 0.0024 0.0054 0.0053
Schistosoma mansoni netrin receptor unc5 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0143 0.0142
Schistosoma mansoni cpg binding protein 0.0062 0.0241 0.0241
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0008 0.0008
Brugia malayi Serotonin receptor 0.0526 0.2502 0.2502
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0015 0.0014
Schistosoma mansoni loxhd1 0.004 0.0133 0.0133
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0207 0.0206
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.0187 0.0187
Schistosoma mansoni adrenodoxin 0.0023 0.0048 0.0048
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0037 0.0139
Leishmania major DNA polymerase kappa, putative 0.002 0.0033 0.0076
Mycobacterium ulcerans electron transfer protein FdxB 0.0023 0.0048 0.0104
Echinococcus granulosus lamin 0.0055 0.0207 0.0206
Brugia malayi hypothetical protein 0.004 0.0133 0.0133
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.0512 0.0511
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0028 0.0073 0.0187
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0093 0.1622
Plasmodium falciparum transporter, putative 0.0042 0.0143 0.2708
Loa Loa (eye worm) hypothetical protein 0.0697 0.334 0.334
Trichomonas vaginalis Ferredoxin 4 0.0023 0.0048 0.0137
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0092 0.0385 0.0385
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0032
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0017 0.0019 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0185 0.0185
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0039 0.0127 0.0126
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.0187 0.0187
Echinococcus multilocularis acetylcholinesterase 0.007 0.0277 0.0277
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0025 0.0063
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0074 0.03 0.0299
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0348 0.1636 0.4776
Echinococcus multilocularis tyrosine kinase 0.0017 0.0017 0.0016
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0697 0.334 0.334
Echinococcus multilocularis acetylcholinesterase 0.007 0.0277 0.0277
Brugia malayi protein-tyrosine kinase 0.0047 0.0164 0.0163
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0012 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0028 0.0078
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0268 0.0724
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0697 0.334 0.334
Echinococcus multilocularis GPCR, family 2 0.0016 0.0015 0.0014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0553 0.0553
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0015 0.0187
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0268 0.0268
Leishmania major ferredoxin, 2fe-2s-like protein 0.0023 0.0048 0.0119
Echinococcus granulosus phospholipase D 0.0094 0.0393 0.0393
Echinococcus granulosus Protein kinase C brain isozyme 0.0074 0.03 0.0299
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0047 0.0164 0.0163
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0051 0.0187 0.0187
Onchocerca volvulus 0.0051 0.0187 0.0541
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0015 0.0015
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0027 0.0066 0.0066
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0697 0.334 0.334
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0033 0.0091
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0027 0.0066 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0025 0.0063
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0531 0.2527 0.2527
Echinococcus granulosus serotonin transporter 0.0249 0.1153 0.1152
Brugia malayi STE20-like kinase MST 0.0236 0.109 0.1089
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0329 0.1542 0.1542
Loa Loa (eye worm) hypothetical protein 0.0051 0.0185 0.0185
Loa Loa (eye worm) serotonin transporter b 0.0249 0.1153 0.1152
Loa Loa (eye worm) norepinephrine transporter 0.0249 0.1153 0.1152
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0023 0.0048 0.6178
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0268 0.0724
Echinococcus granulosus protein kinase c epsilon type 0.0034 0.0101 0.0101
Mycobacterium tuberculosis Conserved protein 0.0037 0.0116 0.0645
Leishmania major farnesyl pyrophosphate synthase 0.0106 0.0452 0.1229
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0012 0.0026
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0014 0.0005 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0167
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0058 0.0167
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0025 0.0055
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0028 0.0073 0.1233
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0028 0.0078
Echinococcus multilocularis serine:threonine protein kinase 38 0.0026 0.0065 0.0064
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0013 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Echinococcus multilocularis thyroid hormone receptor alpha 0.0697 0.334 0.334
Echinococcus multilocularis Protein lozenge 0.0057 0.0214 0.0213
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0027 0.0066 0.0066
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0143 0.0143
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0033 0.0076
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0054 0.0201 0.02
Toxoplasma gondii ferodoxin FD 0.0023 0.0048 0.08
Brugia malayi cytochrome P450 0.0018 0.0025 0.0025
Loa Loa (eye worm) phospholipase D 0.002 0.0034 0.0033
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0137 0.0363
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0236 0.109 0.1089
Loa Loa (eye worm) TK/FER protein kinase 0.0017 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0031
Loa Loa (eye worm) TK protein kinase 0.0047 0.0164 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0697 0.334 0.334
Schistosoma mansoni tyrosine kinase 0.0017 0.0017 0.0017
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0162 0.0162
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0008 0.0004
Echinococcus granulosus RUN 0.004 0.0133 0.0133
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0017 0.0017 0.0016
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0697 0.334 0.334
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0014 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0187 0.0187
Onchocerca volvulus 0.0017 0.0017 0.003
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0012 0.0012
Echinococcus multilocularis geminin 0.0174 0.0783 0.0783
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0268 0.5867
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0116 0.0116
Leishmania major phosphatidylglycerophosphate synthase, putative 0.002 0.0034 0.0079
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0116 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0348 0.1636 0.4776
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0116 0.041
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0017 0.0019 0.0082
Schistosoma mansoni hypothetical protein 0.0174 0.0783 0.0783
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0039 0.0127 0.0341
Onchocerca volvulus 0.0051 0.0187 0.0541
Trichomonas vaginalis glucosylceramidase, putative 0.0348 0.1636 0.4776
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Echinococcus multilocularis phospholipase D 0.0094 0.0393 0.0393
Echinococcus granulosus tyrosine protein kinase Src42A 0.0043 0.0146 0.0145
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.0187 0.0187
Brugia malayi hypothetical protein 0.0051 0.0187 0.0187
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0039 0.0127 0.2373
Echinococcus granulosus tyrosine protein kinase shark 0.0017 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0058 0.0167
Giardia lamblia DINP protein human, muc B family 0.002 0.0033 0.0585
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0015
Schistosoma mansoni lozenge 0.0057 0.0214 0.0214
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0697 0.334 0.334
Loa Loa (eye worm) hypothetical protein 0.0069 0.0273 0.0273
Onchocerca volvulus 0.0104 0.0442 0.1307
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0023 0.0048 0.0048
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.099 0.0989
Loa Loa (eye worm) hypothetical protein 0.004 0.0133 0.0133
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0065 0.0185
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0042 0.0143 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.2061 1 1
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0039 0.0127 0.0126
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0116 0.0335
Schistosoma mansoni sodium/chloride dependent transporter 0.0049 0.0177 0.0177
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.012 0.012
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.0187 0.0187
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0023 0.0048 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.007 0.02
Brugia malayi protein kinase C II. 0.0034 0.0101 0.0101
Giardia lamblia ABC transporter, putative 0.0014 0.0005 0.0012
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0697 0.334 0.334
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.0512 0.2191
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0042 0.0143 0.0142
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0187 0.0187
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0024 0.0054 0.0053
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0093 0.0092
Echinococcus multilocularis tyrosine protein kinase shark 0.0017 0.0017 0.0017
Brugia malayi Dopamine receptor protein 2 0.0051 0.0187 0.0187
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.006 0.0229 0.0615
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0697 0.334 0.334
Mycobacterium ulcerans oxidoreductase 0.0023 0.0048 0.0104
Schistosoma mansoni hypothetical protein 0.004 0.0133 0.0133
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0033 0.0615
Trichomonas vaginalis set domain proteins, putative 0.0245 0.1134 0.331
Trichomonas vaginalis esterase, putative 0.0037 0.0116 0.0335
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0039 0.0127 0.0367
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Echinococcus granulosus c src tyrosine kinase 0.0024 0.0054 0.0053
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0133 0.0133
Trichomonas vaginalis STE family protein kinase 0.0113 0.0486 0.1416
Loa Loa (eye worm) sex muscle abnormal protein 5 0.002 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0179 0.0809 0.0809
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0025 0.0063
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0143 0.0142
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Onchocerca volvulus 0.0051 0.0187 0.0541
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0037 0.009
Entamoeba histolytica hypothetical protein 0.0037 0.0116 0.2474
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0545 0.1485
Trypanosoma cruzi Protein kinase B 0.0032 0.0092 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0104 0.0301
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0116 0.0335
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0167
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0212 0.097 0.4254
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0017 0.0019 0.0082
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0137 0.2944
Echinococcus granulosus dnaJ subfamily B 0.084 0.404 0.404
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0545 0.2342
Trypanosoma cruzi Emopamil binding protein, putative 0.0142 0.0628 0.1714
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0051 0.0187 0.0187
Mycobacterium ulcerans endonuclease IV 0.0078 0.0319 0.1325
Schistosoma mansoni serine/threonine-protein kinase 0.0032 0.0092 0.0092
Echinococcus granulosus tumor protein p63 0.0694 0.3326 0.3326
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0042 0.0143 0.0142
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Brugia malayi beta-lactamase 0.0037 0.0116 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0697 0.334 0.334
Echinococcus granulosus protein kinase c iota type 0.0033 0.0095 0.0095
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.0187 0.0541
Echinococcus multilocularis neuropeptide receptor A26 0.0523 0.2488 0.2487
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0027 0.0066 0.0066
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.0319 1
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0039 0.0127 0.0126
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0133 0.2509
Echinococcus granulosus nervana 2 0.0021 0.0039 0.0039
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0116 0.0335
Schistosoma mansoni amine GPCR 0.0051 0.0187 0.0187
Schistosoma mansoni tyrosine kinase 0.0024 0.0054 0.0054
Schistosoma mansoni opsin-like receptor 0.0051 0.0187 0.0187
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0106 0.0106
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0026 0.0065 0.0064
Brugia malayi Protein K4 0.0017 0.0019 0.0018
Trypanosoma brucei multidrug resistance protein E 0.0014 0.0005 0.0006
Entamoeba histolytica phospholipase D, putative 0.0106 0.0454 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0249 0.1153 0.1153
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0033 0.0112
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0048 0.0119
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0697 0.334 0.334
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0179 0.0809 0.0809
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0021 0.0039 0.0039
Brugia malayi Protein kinase domain containing protein 0.0022 0.0042 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0531 0.2527 0.7379
Brugia malayi Phospholipase D. Active site motif family protein 0.0037 0.0117 0.0116
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0043 0.0146 0.0145
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0027 0.0066 0.1088
Trypanosoma brucei cytochrome P450, putative 0.0036 0.0113 0.0303
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0186 0.0541
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0054 0.0201 0.02
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.0187 0.0187
Brugia malayi Serotonin receptor 0.0051 0.0187 0.0187
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0033 0.0032
Entamoeba histolytica protein kinase, putative 0.0051 0.0186 0.4042
Loa Loa (eye worm) runx1 0.0057 0.0214 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0031
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.0187 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0033 0.0082
Echinococcus granulosus cpg binding protein 0.0062 0.0241 0.024
Onchocerca volvulus Putative phospholipase D 0.002 0.0034 0.008
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0162 0.0439
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0026 0.0065 0.0064
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0067 0.0066
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0037 0.0116 0.2474
Loa Loa (eye worm) hypothetical protein 0.004 0.0133 0.0133
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0012 0.0011
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0027 0.0066 0.0066
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0201 0.02
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0027 0.0066 0.1088
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0023 0.0048 0.0703
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.0512 0.0511
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0186 0.0541
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.03 0.03
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0037 0.0116 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0065 0.0065
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0032 0.0092 0.0239
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0162 0.0432
Echinococcus granulosus g protein coupled receptor 0.0051 0.0187 0.0187
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0113 0.0112
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0329 0.1542 0.4605
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1666 0.8072 0.8072
Loa Loa (eye worm) hypothetical protein 0.0042 0.0143 0.0142
Onchocerca volvulus 0.0051 0.0187 0.0541
Brugia malayi nuclear hormone receptor family member odr-7 0.0329 0.1542 0.1541
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0028 0.0073 0.0073
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0116 0.0645
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0268 0.0268
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.0187 0.0187
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0113 0.0112
Loa Loa (eye worm) hypothetical protein 0.0329 0.1542 0.1541
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0143 0.0143
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0368 0.1734 0.1734
Loa Loa (eye worm) hypothetical protein 0.0055 0.0207 0.0206
Schistosoma mansoni trans-prenyltransferase 0.0027 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.0018 0.0025 0.0025
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0027 0.0066 0.0066
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0329 0.1542 0.1541
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0187 0.0187
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0023 0.0048 0.08
Echinococcus multilocularis tyrosine protein kinase Srms 0.0047 0.0164 0.0163
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0014
Schistosoma mansoni opsin-like receptor 0.0051 0.0187 0.0187
Schistosoma mansoni cytochrome P450 0.0018 0.0025 0.0025
Echinococcus granulosus thyroid hormone receptor alpha 0.0329 0.1542 0.1541
Echinococcus multilocularis ferredoxin adrenodoxin 0.0023 0.0048 0.0048
Echinococcus multilocularis allatostatin A receptor 0.0051 0.0187 0.0187
Echinococcus multilocularis dnaJ subfamily B 0.084 0.404 0.404
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0028 0.0073 0.0073
Trichomonas vaginalis glucosylceramidase, putative 0.0531 0.2527 0.7379
Echinococcus multilocularis carboxylesterase 5A 0.007 0.0277 0.0277
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0697 0.334 0.334
Echinococcus granulosus g protein coupled receptor 0.0051 0.0187 0.0187
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0017 0.0019 0.0082
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0187
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0023 0.0048 0.0104
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0017
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0201 0.02
Brugia malayi hypothetical protein 0.0368 0.1734 0.1734
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0024 0.0024
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.0065 0.0064
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.011 0.0473 0.0472
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0024 0.0054 0.0053
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0697 0.334 0.334
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.0187 0.0187
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0143 0.0142
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0585 0.2792 0.2791

Activities

Activity type Activity value Assay description Source Reference
ED50 (binding) mg kg-1 Effective dose required to inhibit testosterone propionate-stimulated prostate weight gain by 50% using [3H]- R1881 as the radioligand; ND= Not done ChEMBL. 7990121
RBA (binding) < 0.01 Relative binding affinity (RBA) towards androgen receptor in rat ventral prostate cytosol, following 18 h incubation time period ChEMBL. 7990121
RBA (binding) = 0.11 Relative binding affinity (RBA) towards androgen receptor in rat ventral prostate cytosol, following 1 h incubation time period ChEMBL. 7990121

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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