Detailed information for compound 147781

Basic information

Technical information
  • TDR Targets ID: 147781
  • Name: 4-[(2S,3R)-4-(4-hydroxy-3-methoxyphenyl)-2,3- dimethylbutyl]benzene-1,2-diol
  • MW: 316.391 | Formula: C19H24O4
  • H donors: 3 H acceptors: 3 LogP: 4.63 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(ccc1O)C[C@H]([C@H](Cc1ccc(c(c1)O)O)C)C
  • InChi: 1S/C19H24O4/c1-12(8-14-4-6-16(20)18(22)10-14)13(2)9-15-5-7-17(21)19(11-15)23-3/h4-7,10-13,20-22H,8-9H2,1-3H3/t12-,13+/m0/s1
  • InChiKey: QKHJBWUGXMKHAK-QWHCGFSZSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-[(2S,3R)-4-(4-hydroxy-3-methoxy-phenyl)-2,3-dimethyl-butyl]benzene-1,2-diol
  • 4-[(2S,3R)-4-(4-hydroxy-3-methoxy-phenyl)-2,3-dimethyl-butyl]pyrocatechol
  • heminordihydroguaiaretic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Glycine max Seed lipoxygenase-1 Starlite/ChEMBL References
Homo sapiens arachidonate 15-lipoxygenase Starlite/ChEMBL References
Homo sapiens arachidonate 12-lipoxygenase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma japonicum IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma japonicum ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative Get druggable targets OG5_127482 All targets in OG5_127482
Echinococcus granulosus arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Echinococcus multilocularis arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus arachidonate 5 lipoxygenase arachidonate 12-lipoxygenase 663 aa 662 aa 22.8 %
Echinococcus granulosus arachidonate 5 lipoxygenase arachidonate 15-lipoxygenase 662 aa 590 aa 23.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi beta-lactamase 0.0041 0.0143 0.0143
Onchocerca volvulus 0.0109 0.0501 0.1924
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0663 0.1975
Schistosoma mansoni adenoreceptor 0.0046 0.0168 0.022
Brugia malayi nuclear hormone receptor 0.0044 0.0162 0.0162
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0038 0.0045
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0134 0.0169
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0044 0.0162 0.0212
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0021 0.0051
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0063 0.0066
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0046 0.0168 0.0741
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0055 0.0489
Echinococcus multilocularis geminin 0.1416 0.7406 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0044 0.0162 0.0162
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0009 0.0073
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0099
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0253 0.0336
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0121 0.0157
Leishmania major arginine N-methyltransferase-like protein 0.0061 0.0247 0.0772
Trichomonas vaginalis DNA polymerase eta, putative 0.0078 0.0338 0.0433
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0296 0.149 0.149
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0009 0.0073
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0044 0.0161 0.0203
Onchocerca volvulus 0.0046 0.0168 0.0637
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0168 0.022
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0046 0.0168 0.022
Schistosoma mansoni hypothetical protein 0.0034 0.0105 0.0135
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0041 0.0145 0.0189
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0134 0.0134
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0021 0.0021
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0284 0.0363
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0067 0.0284 0.2691
Brugia malayi Tachykinin-like peptides receptor 99D 0.0046 0.0168 0.0168
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0488 0.0488
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0059 0.0073
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Brugia malayi nuclear receptor NHR-88 0.0044 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0044 0.0162 0.0713
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0134 0.0175
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0073 0.0092
Loa Loa (eye worm) hypothetical protein 0.0044 0.0162 0.0713
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0445 0.0594
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0251 0.0332
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0041 0.0143 0.0628
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0067 0.0284 0.0377
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0127
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0168 0.022
Brugia malayi GnHR receptor homolog 0.0046 0.0168 0.0168
Brugia malayi G-protein coupled receptor 0.0046 0.0168 0.0168
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0021 0.0154
Loa Loa (eye worm) ctsf protein 0.0015 0.0005 0.0022
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0009 0.0014
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0038 0.0045
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0047 0.0174 0.0765
Echinococcus granulosus smad 0.0025 0.0059 0.0073
Brugia malayi ORL1-like opioid receptor 0.0046 0.0168 0.0168
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0015 0.0066
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0046 0.0168 0.022
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0075 0.0332
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0143 0.0179
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0022 0.0323
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.149 0.1929
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0117 0.0547 0.0733
Brugia malayi Cathepsin L-like precursor 0.0015 0.0005 0.0005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Echinococcus multilocularis sex peptide receptor 0.0046 0.0168 0.022
Brugia malayi hypothetical protein 0.0043 0.0157 0.0157
Mycobacterium ulcerans hypothetical protein 0.0041 0.0143 0.0169
Brugia malayi hypothetical protein 0.0025 0.0057 0.0057
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.061 0.315 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0443 0.2269 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Plasmodium falciparum inorganic anion exchanger, inorganic anion antiporter 0.0039 0.0135 0.1122
Echinococcus multilocularis G protein coupled receptor 139 0.0046 0.0168 0.022
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0067 0.0284 0.5146
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0061 0.0247 0.0315
Echinococcus granulosus somatostatin receptor 0.0046 0.0168 0.022
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0073 0.0092
Schistosoma mansoni hypothetical protein 0.0072 0.031 0.0413
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0168 0.022
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0042 0.0051
Loa Loa (eye worm) hypothetical protein 0.0099 0.0448 0.1976
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0046 0.0168 0.022
Schistosoma mansoni alpha-glucosidase 0.0152 0.073 0.098
Echinococcus multilocularis jun protein 0.0106 0.0485 0.0649
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0121 0.1
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0108 0.0134
Brugia malayi putative neuropeptide receptor 0.0046 0.0168 0.0168
Brugia malayi Protein arginine N-methyltransferase 0.0034 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0095 0.0427 0.1883
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0067 0.0284 0.0377
Schistosoma mansoni amine GPCR 0.0046 0.0168 0.022
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0054 0.021 0.0278
Loa Loa (eye worm) hypothetical protein 0.0118 0.055 0.2422
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni terminal deoxycytidyl transferase 0.0052 0.0201 0.0265
Onchocerca volvulus 0.0028 0.0075 0.0279
Schistosoma mansoni smad1 5 8 and 0.0025 0.0059 0.0073
Loa Loa (eye worm) hypothetical protein 0.0124 0.0583 0.257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0067 0.0284 0.2691
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0021 0.0156
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0046 0.0168 0.0741
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0034 0.0108 0.0139
Echinococcus granulosus methyltransferase protein 5 0.0034 0.0108 0.0139
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0051 0.0062
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0042 0.0149 0.2658
Brugia malayi Cathepsin L-like precursor 0.0015 0.0005 0.0005
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0009 0.0041
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Schistosoma mansoni hypothetical protein 0.0399 0.2033 0.274
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0044 0.0162 0.0212
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Loa Loa (eye worm) glutaminase 2 0.0224 0.1112 0.4902
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0067 0.0284 0.2691
Brugia malayi jmjC domain containing protein 0.0018 0.0022 0.0022
Brugia malayi RNA binding protein 0.0076 0.0332 0.0332
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0061 0.0247 0.209
Leishmania major protein kinase A catalytic subunit isoform 2 0.0042 0.0149 0.0459
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0168 0.022
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0084 0.037 0.0493
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0953 0.1231
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0168 0.022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0023 0.0024
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0044 0.0161 0.1505
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.005 0.0191 0.0233
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0022 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0168 0.022
Onchocerca volvulus Cathepsin F homolog 0.0015 0.0005 0.0007
Echinococcus multilocularis smad 0.0025 0.0059 0.0073
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0038 0.0045
Brugia malayi putative neuropeptide receptor NPR1 0.0046 0.0168 0.0168
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0953 0.1231
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0042 0.0149 0.0195
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0046 0.0168 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0044 0.0162 0.0713
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0067 0.0284 0.2407
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0021 0.0021
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0061 0.0247 0.0327
Loa Loa (eye worm) AGC/PKA protein kinase 0.0042 0.0149 0.0657
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0445 0.0594
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0022 0.0024
Loa Loa (eye worm) TYRA-2 protein 0.0046 0.0168 0.0741
Brugia malayi Pre-SET motif family protein 0.0443 0.2269 0.2269
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0332 0.0441
Brugia malayi Smad1 0.0025 0.0059 0.0059
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0051 0.0063
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0044 0.0162 0.0212
Echinococcus granulosus serotonin receptor 0.0046 0.0168 0.022
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0168 0.022
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0663 0.0845
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0063 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0162 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0034 0.0105 0.0135
Echinococcus granulosus G protein coupled receptor 139 0.0046 0.0168 0.022
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0021 0.0091
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0051 0.0051
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0051 0.0063
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0044 0.0162 0.0713
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0021 0.0021
Brugia malayi jmjC domain containing protein 0.0018 0.0022 0.0022
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0021 0.0091
Brugia malayi isocitrate dehydrogenase 0.0015 0.0009 0.0009
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0143 0.0179
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0017 0.0015 0.0014
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0157 0.0205
Brugia malayi G protein-coupled receptor 0.0046 0.0168 0.0168
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0023 0.0051 0.0068
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0284 0.2691
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0442 0.0591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Brugia malayi AKH receptor 0.0046 0.0168 0.0168
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0044 0.0162 0.0212
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0038 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0168 0.022
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0009 0.0034
Brugia malayi polk-prov protein 0.0042 0.0149 0.0149
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0029 0.0021
Brugia malayi hypothetical protein 0.0021 0.0038 0.0038
Trypanosoma cruzi polo-like protein kinase, putative 0.0078 0.0339 0.3225
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0168 0.022
Onchocerca volvulus Neuropeptide F receptor homolog 0.0046 0.0168 0.0637
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0211 0.1043 0.1402
Schistosoma mansoni bromodomain containing protein 0.0075 0.0321 0.0427
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0134 0.0175
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0434 0.1367
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0046 0.0168 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.1472 0.7704 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0046 0.0168 0.022
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0021 0.0154
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0339 0.0435
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0063 0.0066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0149 0.1395
Brugia malayi hypothetical protein 0.0021 0.0038 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1432 0.1854
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.0338 0.3213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Loa Loa (eye worm) hypothetical protein 0.005 0.0194 0.0855
Brugia malayi hypothetical protein 0.0023 0.0051 0.0051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0162 0.0212
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0134 0.0169
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0034 0.0108 0.0474
Echinococcus granulosus tar DNA binding protein 0.0076 0.0332 0.0441
Onchocerca volvulus 0.0041 0.0143 0.0539
Schistosoma mansoni histamine h1 receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0038 0.0038
Echinococcus multilocularis FTZ F1 alpha 0.0137 0.0649 0.0871
Loa Loa (eye worm) hypothetical protein 0.0042 0.0149 0.0657
Trypanosoma brucei unspecified product 0.0036 0.0116 0.1076
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0121 0.0157
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0067 0.0284 0.0377
Plasmodium vivax multidomain scavenger receptor, putative 0.0071 0.0305 0.2586
Onchocerca volvulus Cathepsin L homolog 0.0015 0.0005 0.0007
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0022 0.0151
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0021 0.0154
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0168 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Loa Loa (eye worm) cysteine protease 0.0015 0.0005 0.0022
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0034 0.0108 0.0992
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0143 0.0186
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0055 0.0489
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0046 0.0168 0.0741
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0046 0.0168 0.022
Treponema pallidum hypothetical protein 0.0044 0.0158 0.0281
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0044 0.0162 0.0713
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0037 0.0316
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0041 0.0145 0.0189
Toxoplasma gondii exonuclease III APE 0.0037 0.0121 0.2138
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0044 0.0162 0.0212
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0042 0.0149 0.1391
Loa Loa (eye worm) hypothetical protein 0.0044 0.0162 0.0713
Loa Loa (eye worm) hypothetical protein 0.0041 0.0143 0.0628
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0009 0.0034
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0134 0.2388
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Schistosoma mansoni flap endonuclease-1 0.0023 0.0049 0.0059
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0105 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0445 0.0594
Loa Loa (eye worm) hypothetical protein 0.0052 0.0201 0.0887
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.0338 0.3213
Schistosoma mansoni cpg binding protein 0.0032 0.0095 0.0122
Onchocerca volvulus Bile acid receptor homolog 0.0044 0.0162 0.0613
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0029 0.0207
Leishmania major hypothetical protein, conserved 0.0041 0.0143 0.0439
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0434 0.058
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0054 0.021 0.0257
Schistosoma mansoni coup transcription factor 0.0044 0.0162 0.0212
Mycobacterium leprae Probable transmembrane transport protein 0.0285 0.1432 0.4458
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0021 0.0289
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0022 0.0024
Brugia malayi Dopamine receptor 0.0046 0.0168 0.0168
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0434 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0044 0.0161 0.071
Schistosoma mansoni lamin 0.0031 0.0091 0.0116
Onchocerca volvulus 0.0102 0.0464 0.1779
Echinococcus granulosus Polycystic kidney disease protein 0.0071 0.0305 0.0405
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0108 0.0991
Echinococcus granulosus expressed conserved protein 0.009 0.0404 0.0539
Loa Loa (eye worm) hypothetical protein 0.0023 0.0051 0.0226
Echinococcus granulosus transcription factor btf3 0.0034 0.0108 0.0139
Echinococcus granulosus allatostatin A receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0047 0.0175 0.0773
Plasmodium vivax SET domain protein, putative 0.0064 0.0266 0.2253
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni neuropeptide receptor 0.0046 0.0168 0.022
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0067 0.0284 0.0377
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0077 0.0332 0.104
Echinococcus multilocularis protein dispatched 1 0.0047 0.0176 0.0231
Echinococcus granulosus zinc finger protein 0.0024 0.0055 0.0068
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0034 0.0108 0.1894
Loa Loa (eye worm) beta-lactamase 0.0041 0.0143 0.0628
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0067 0.0284 0.0377
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0016 0.0011 0.0059
Schistosoma mansoni loxhd1 0.0071 0.0305 0.0405
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.001 0.0096
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1432 0.1854
Entamoeba histolytica hypothetical protein 0.0034 0.0108 0.0327
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0652 0.0874
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0044 0.0161 0.1505
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0077 0.0332 0.1462
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0143 0.0218
Mycobacterium ulcerans carbonic anhydrase 0.061 0.315 0.4079
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0034 0.0108 0.1894
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.149 0.1929
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0044 0.0161 0.1045
Loa Loa (eye worm) hypothetical protein 0.0069 0.0293 0.1292
Echinococcus granulosus dna polymerase kappa 0.0078 0.0338 0.045
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0303 0.0403
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0299 0.0398
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0054 0.021 0.0278
Echinococcus granulosus bloom syndrome protein 0.0023 0.0051 0.0062
Toxoplasma gondii melibiase subfamily protein 0.0117 0.0547 1
Onchocerca volvulus 0.0046 0.0168 0.0637
Echinococcus multilocularis zinc finger protein 0.0024 0.0055 0.0068
Loa Loa (eye worm) hypothetical protein 0.0044 0.0161 0.071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0051 0.0226
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0022 0.0172
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0031 0.0036
Mycobacterium ulcerans beta-lactamase 0.0041 0.0143 0.0169
Trypanosoma brucei unspecified product 0.0036 0.0116 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0339 0.0435
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0219 0.0219
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0168 0.022
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0042 0.0149 0.0195
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0028
Onchocerca volvulus 0.0015 0.0005 0.0007
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0021 0.0154
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0044 0.0162 0.0162
Brugia malayi Glycosyl hydrolases family 31 protein 0.0177 0.086 0.086
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0044 0.0161 0.0497
Schistosoma mansoni opsin-like receptor 0.0046 0.0168 0.022
Echinococcus multilocularis survival motor neuron protein 1 0.0271 0.1358 0.1828
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0006 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.149 0.1929
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0046 0.0168 0.022
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0021 0.0051
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0036 0.0269
Schistosoma mansoni ap endonuclease 0.0037 0.0121 0.0157
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0042 0.0149 0.1243
Loa Loa (eye worm) fli-1 protein 0.0214 0.1059 0.4669
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0143 0.0143
Toxoplasma gondii Alpha-galactosidase 0.0017 0.0015 0.0191
Onchocerca volvulus 0.0046 0.0168 0.0637
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0012 0.0076
Echinococcus granulosus lamin 0.0031 0.0091 0.0116
Echinococcus granulosus flap endonuclease 1 0.0025 0.0062 0.0077
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0044 0.0158 0.0243
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0133 0.0166
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.03 0.0399
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0061 0.0247 0.4469
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0062 0.0346
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Schistosoma mansoni biogenic amine receptor 0.0046 0.0168 0.022
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0034 0.0108 0.0328
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0095 0.0427 0.4072
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0143 0.0179
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0143 0.1328
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0266 0.0353
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0339 0.0435
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0109 0.0501 0.067
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0234 0.4232
Loa Loa (eye worm) hypothetical protein 0.0143 0.0682 0.3005
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0067 0.0284 0.0888
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0284 0.0363
Echinococcus granulosus small conductance calcium activated potassium 0.0138 0.0657 0.0881
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0108 0.0134
Brugia malayi MH2 domain containing protein 0.0364 0.1851 0.1851
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0168 0.022
Mycobacterium ulcerans hypothetical protein 0.0044 0.0158 0.0189
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0015 0.0005 0.0006
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0057 0.0452
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0061 0.0247 0.0315
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0168 0.022
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0137 0.0649 0.0871
Toxoplasma gondii bicoid-interacting protein BIN3 0.0034 0.0108 0.1894
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Brugia malayi Cathepsin L-like precursor 0.0015 0.0005 0.0005
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0021 0.0051
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0143 0.0186
Echinococcus multilocularis orexin receptor type 2 0.0046 0.0168 0.022
Leishmania major hypothetical protein, conserved 0.0025 0.0057 0.0168
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0067 0.0284 0.0353
Echinococcus granulosus g protein coupled receptor 0.0046 0.0168 0.022
Schistosoma mansoni zinc finger protein 0.0024 0.0055 0.0068
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0168 0.022
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0034 0.0108 0.0134
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0105 0.0135
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1432 0.1854
Onchocerca volvulus 0.0031 0.0091 0.0338
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0285 0.1432 0.2324
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0067 0.0284 0.8424
Schistosoma mansoni amine GPCR 0.0046 0.0168 0.022
Onchocerca volvulus 0.0032 0.0094 0.0351
Schistosoma mansoni retinoic acid receptor RXR 0.0044 0.0162 0.0212
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Brugia malayi MH2 domain containing protein 0.0025 0.0059 0.0059
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0051 0.0051
Brugia malayi Ets-domain containing protein 0.0071 0.03 0.03
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0042 0.0149 0.0195
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0284 0.2691
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0077 0.0332 0.0441
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0078 0.0339 0.0452
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0168 0.022
Echinococcus granulosus dna polymerase eta 0.0052 0.0201 0.0265
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0015 0.0005 0.0022
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0046 0.0168 0.022
Schistosoma mansoni amine GPCR 0.0046 0.0168 0.022
Schistosoma mansoni myosin xvIII 0.0046 0.0168 0.022
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0279
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni amine GPCR 0.0046 0.0168 0.022
Echinococcus multilocularis g-protein coupled receptor 0.0046 0.0168 0.022
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0121 0.037
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0051 0.0051
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0146 0.0191
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0279
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0039 0.0135 0.1256
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0059 0.0073
Brugia malayi beta-lactamase family protein 0.0041 0.0143 0.0143
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0021 0.0154
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0042 0.0149 0.1391
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0341 0.0454
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.03 0.0399
Loa Loa (eye worm) transcription factor SMAD2 0.0364 0.1851 0.8159
Schistosoma mansoni single-minded 0.0043 0.0152 0.0199
Schistosoma mansoni patched 1 0.0041 0.0145 0.0189
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0083 0.0368 0.3129
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0057 0.0966
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0021 0.0051
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0063 0.0186
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0063 0.0186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Brugia malayi neuropeptide F receptor 0.0046 0.0168 0.0168
Echinococcus granulosus RUN 0.0071 0.0305 0.0405
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0009 0.0005
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0168 0.022
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0284 0.2691
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0303 0.0403
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni alpha glucosidase 0.0039 0.0134 0.0175
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0168 0.022
Brugia malayi hypothetical protein 0.0016 0.0011 0.0011
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0067 0.0283 0.0376
Echinococcus multilocularis Polycystic kidney disease protein 0.0071 0.0305 0.0405
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0211 0.1043 0.3301
Mycobacterium ulcerans lipase LipD 0.0041 0.0143 0.0169
Brugia malayi G protein-coupled receptor F59B2.13 0.0046 0.0168 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0488 0.2149
Schistosoma mansoni ets-related 0.0214 0.1059 0.1425
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0121 0.0151
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0134 0.0169
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0211 0.1043 0.1349
Trypanosoma brucei glucosidase, putative 0.0039 0.0134 0.125
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1008 0.1303
Schistosoma mansoni nuclear receptor 0.0021 0.0038 0.0045
Echinococcus granulosus muscleblind protein 0.0146 0.0697 0.0934
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0022 0.0099
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0117 0.0547 0.0733
Brugia malayi Pre-SET motif family protein 0.0064 0.0266 0.0266
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0077 0.0332 0.0415
Onchocerca volvulus 0.0046 0.0168 0.0637
Plasmodium falciparum protease, putative 0.0044 0.0158 0.1318
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.0338 0.0423
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0143 0.0218
Echinococcus multilocularis muscleblind protein 0.0146 0.0697 0.0934
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0016 0.0012 0.014
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0168 0.022
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0046 0.0168 0.022
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0099
Echinococcus multilocularis lamin 0.0031 0.0091 0.0116
Mycobacterium ulcerans integral membrane protein 0.0044 0.0158 0.0189
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0222 0.2097
Loa Loa (eye worm) hypothetical protein 0.0071 0.0305 0.1343
Loa Loa (eye worm) hypoxia-induced factor 1 0.0132 0.0623 0.2747
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0009 0.0005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0168 0.022
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0046 0.0168 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.015 0.1403
Loa Loa (eye worm) Smad1 0.0025 0.0059 0.0258
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0054 0.021 0.0257
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0038 0.0135
Echinococcus granulosus single minded 2 0.0032 0.0094 0.012
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0063 0.0066
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0044 0.0162 0.0212
Schistosoma mansoni rab6-interacting 0.0071 0.0305 0.0405
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0046 0.0168 0.022
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0011 0.0053
Brugia malayi MH1 domain containing protein 0.0025 0.0059 0.0059
Brugia malayi Muscleblind-like protein 0.0146 0.0697 0.0697
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0015 0.0015
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0038 0.0045
Trypanosoma cruzi Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0016 0.0011 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0953 0.1231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Mycobacterium tuberculosis Conserved protein 0.0041 0.0143 0.0218
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0009 0.0005
Leishmania major cathepsin L-like protease 0.0015 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Brugia malayi hypothetical protein 0.0095 0.0427 0.0427
Brugia malayi hypothetical protein 0.0143 0.0682 0.0682
Echinococcus multilocularis protein patched 0.0041 0.0145 0.0189
Loa Loa (eye worm) hypothetical protein 0.0044 0.0162 0.0713
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0034 0.0108 0.0992
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0547 0.0733
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0162 0.0162
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0039 0.0135 0.0159
Brugia malayi hypothetical protein 0.008 0.0348 0.0348
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0143 0.1187
Echinococcus granulosus protein arginine N methyltransferase 8 0.0061 0.0247 0.0327
Brugia malayi Ets-domain containing protein 0.0071 0.03 0.03
Leishmania major hypothetical protein, conserved 0.0016 0.0011 0.002
Entamoeba histolytica hypothetical protein 0.0043 0.0157 0.0485
Onchocerca volvulus 0.0041 0.0143 0.0539
Schistosoma mansoni RAR-like nuclear receptor 0.0044 0.0162 0.0212
Echinococcus multilocularis neuropeptide FF receptor 2 0.0046 0.0168 0.022
Schistosoma mansoni nuclear receptor 0.0021 0.0038 0.0045
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0055 0.093
Leishmania major hypothetical protein, conserved 0.0016 0.0011 0.002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0137 0.0649 0.0649
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0063 0.0063
Brugia malayi nuclear receptor RXR 0.0021 0.0038 0.0038
Schistosoma mansoni aryl hydrocarbon receptor 0.0043 0.0152 0.0199
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Echinococcus granulosus geminin 0.1416 0.7406 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0149 0.0195
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0266 0.0353
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0034 0.0108 0.0992
Entamoeba histolytica cysteine proteinase, putative 0.0015 0.0005 0.0001
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0168 0.0741
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0332 0.0441
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0046 0.0168 0.022
Trypanosoma cruzi polo-like protein kinase, putative 0.0078 0.0339 0.3225
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0021 0.0154
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0121 0.0141
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Echinococcus multilocularis transcription factor btf3 0.0034 0.0108 0.0139
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0038 0.0321
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0296 0.149 0.6567
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Echinococcus granulosus jun protein 0.0106 0.0485 0.0649
Echinococcus granulosus alpha 1A adrenergic receptor 0.0046 0.0168 0.022
Schistosoma mansoni hypothetical protein 0.0092 0.0415 0.0554
Schistosoma mansoni hypothetical protein 0.0034 0.0105 0.0135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0067 0.0283 0.0376
Brugia malayi Melibiase family protein 0.0078 0.0341 0.0341
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0063 0.0066
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0121 0.0151
Echinococcus granulosus dnaJ subfamily B 0.0399 0.2033 0.274
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0143 0.1328
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0143 0.0628
Echinococcus multilocularis serotonin receptor 0.0046 0.0168 0.022
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0067 0.0284 0.0888
Loa Loa (eye worm) hypothetical protein 0.0034 0.0105 0.0462
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0134 0.0169
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0078 0.0339 0.1496
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0038 0.0321
Brugia malayi CAAX amino terminal protease family protein 0.0211 0.1043 0.1043
Trypanosoma brucei unspecified product 0.0071 0.0304 0.2886
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0044 0.0162 0.0212
Schistosoma mansoni hypothetical protein 0.004 0.0137 0.0179
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0038 0.0038
Onchocerca volvulus Glucosylceramidase homolog 0.0194 0.0953 0.3668
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0009 0.0005
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0061 0.0247 0.0327
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0052 0.0201 0.0265
Leishmania major DNA polymerase eta, putative 0.0016 0.0012 0.0025
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0061 0.0247 0.0327
Echinococcus multilocularis G-protein coupled receptor, putative 0.0046 0.0168 0.022
Onchocerca volvulus 0.0026 0.0063 0.0232
Entamoeba histolytica hypothetical protein 0.0043 0.0157 0.0485
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0143 0.0218
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0014
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0091 0.04
Trypanosoma cruzi ISWI complex protein 0.0018 0.0021 0.0155
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0038 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0063 0.0063
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0046 0.0168 0.022
Chlamydia trachomatis hypothetical protein 0.0044 0.0158 0.4253
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0137 0.0649 0.0649
Brugia malayi Trypsin family protein 0.0109 0.0501 0.0501
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0488 0.0488
Mycobacterium tuberculosis Conserved protein 0.0041 0.0143 0.0218
Entamoeba histolytica PH domain containing protein kinase, putative 0.0042 0.0149 0.0459
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0063 0.0041
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0044 0.0162 0.0212
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0106 0.0485 0.0649
Loa Loa (eye worm) hypothetical protein 0.0023 0.0051 0.0226
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0145 0.0639
Loa Loa (eye worm) hypothetical protein 0.006 0.0246 0.1085
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0121 0.0763
Echinococcus granulosus lipoxygenase domain containing protein 0.0071 0.0305 0.0405
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0339 0.0435
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0044 0.0162 0.0162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0168 0.022
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0062 0.0489
Brugia malayi glucose-6-phosphate dehydrogenase 0.0077 0.0332 0.0332
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0051 0.0226
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0055 0.0068
Brugia malayi neuropeptide F receptor 0.0046 0.0168 0.0168
Brugia malayi ecdysteroid receptor 0.0044 0.0162 0.0162
Brugia malayi conserved hypotetical protein 0.0021 0.0038 0.0038
Trypanosoma cruzi cysteine peptidase, putative 0.0015 0.0005 0.0003
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0077 0.0332 0.315
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0105 0.0135
Echinococcus multilocularis histone h3 methyltransferase 0.0124 0.0583 0.0781
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0162 0.0212
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0143 0.0218
Echinococcus granulosus peptide allatostatin:somatostatin 0.0046 0.0168 0.022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0084 0.037 0.0493
Schistosoma mansoni cpg binding protein 0.0028 0.0075 0.0095
Loa Loa (eye worm) RecQ helicase 0.0023 0.0051 0.0225
Echinococcus granulosus protein arginine N methyltransferase 7 0.0034 0.0108 0.0139
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0168 0.0741
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0168 0.022
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0061 0.0247 0.0315
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0044 0.0161 0.0211
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0046 0.0168 0.0741
Echinococcus granulosus fmrfamide receptor 0.0046 0.0168 0.022
Brugia malayi jmjC domain containing protein 0.0018 0.0022 0.0022
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0023 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0168 0.022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0023 0.0024
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0047 0.0175 0.077
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0062 0.1045
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0078 0.0339 0.1065
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0547 0.0733
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0031 0.0036
Onchocerca volvulus 0.0015 0.0005 0.0007
Mycobacterium ulcerans carbonic anhydrase 0.1472 0.7704 1
Loa Loa (eye worm) hypothetical protein 0.0106 0.0488 0.2149
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0276 0.1384 0.1863
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0266 0.4817
Schistosoma mansoni hypothetical protein 0.1416 0.7406 1
Brugia malayi Bromodomain containing protein 0.0044 0.0161 0.0161
Onchocerca volvulus 0.0044 0.0162 0.0613
Schistosoma mansoni opsin-like receptor 0.0046 0.0168 0.022
Brugia malayi Dopamine receptor protein 2 0.0046 0.0168 0.0168
Leishmania major DNA polymerase kappa, putative 0.0016 0.0012 0.0025
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0077 0.0332 0.0441
Schistosoma mansoni neuropeptide receptor 0.0046 0.0168 0.022
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0222 0.2097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0168 0.022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0168 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Echinococcus granulosus histone lysine methyltransferase setb 0.0084 0.037 0.0493
Echinococcus granulosus dro:myosuppressin receptor 0.0046 0.0168 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0108 0.0134
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0034 0.0108 0.0134
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0953 0.1231
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0143 0.0218
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0953 0.1231
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1008 0.1303
Giardia lamblia DINP protein human, muc B family 0.0058 0.0235 0.1569
Entamoeba histolytica PH domain containing protein kinase, putative 0.0042 0.0149 0.0459
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0061 0.0247 0.0327
Brugia malayi Histone-lysine N-methyltransferase, H3 lysine-79 specific 0.0124 0.0583 0.0583
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0547 0.0733
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Leishmania major DNA polymerase eta, putative 0.0052 0.0201 0.0625
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0063 0.0186
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0339 0.0435
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0953 0.1231
Leishmania major protein kinase A catalytic subunit isoform 1 0.0042 0.0149 0.0459
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0332 0.0441
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Brugia malayi steroid hormone receptor 0.0044 0.0162 0.0162
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0121 0.112
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0059 0.0073
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0073 0.0092
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0016 0.0012 0.014
Loa Loa (eye worm) hypothetical protein 0.0138 0.0657 0.2894
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Schistosoma mansoni rab6-interacting 0.0071 0.0305 0.0405
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0052 0.0201 0.0887
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0022 0.0024
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.1432 0.4539
Schistosoma mansoni neuropeptide receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0127
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0022 0.0024
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0157 0.0205
Leishmania major cathepsin L-like protease 0.0015 0.0005 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0168 0.022
Echinococcus multilocularis dro:myosuppressin receptor 0.0046 0.0168 0.022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0162 0.0212
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.086 0.1155
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0055 0.0055
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0038 0.0045
Trichomonas vaginalis esterase, putative 0.0041 0.0143 0.0179
Schistosoma mansoni neuropeptide receptor 0.0046 0.0168 0.022
Echinococcus multilocularis expressed conserved protein 0.009 0.0404 0.0539
Leishmania major cathepsin L-like protease 0.0056 0.0222 0.0692
Trichomonas vaginalis set domain proteins, putative 0.0504 0.2592 0.3361
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0234 0.1164 0.3593
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0168 0.022
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0143 0.0218
Brugia malayi hypothetical protein 0.0071 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0031 0.0091 0.04
Toxoplasma gondii ABC1 family protein 0.0041 0.0143 0.2538
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0168 0.022
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0137 0.0649 0.0871
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1432 0.1854
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0062 0.0077
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0168 0.022
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0134 0.125
Trypanosoma cruzi cruzipain precursor, putative 0.0056 0.0222 0.2097
Schistosoma mansoni alpha-1 adrenergic receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0041 0.0143 0.0628
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0083 0.0368 0.6689
Schistosoma mansoni jun-related protein 0.0087 0.0385 0.0513
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0025 0.0058 0.051
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0134 0.0413
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0077 0.0332 0.0441
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0134 0.0169
Loa Loa (eye worm) hypothetical protein 0.0084 0.037 0.163
Schistosoma mansoni hypothetical protein 0.0087 0.0385 0.0513
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0168 0.022
Brugia malayi ImpB/MucB/SamB family protein 0.0052 0.0201 0.0201
Brugia malayi Melatonin receptor type 1A 0.0046 0.0168 0.0168
Giardia lamblia Hypothetical protein 0.0211 0.1043 0.7258
Onchocerca volvulus 0.0015 0.0005 0.0007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1432 0.1854
Onchocerca volvulus 0.0021 0.0038 0.0135
Onchocerca volvulus Cathepsin L homolog 0.0015 0.0005 0.0007
Loa Loa (eye worm) DR-78 0.0021 0.0038 0.0168
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0067 0.0284 1
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0023 0.0046 0.0766
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0149 0.0195
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0022 0.0024
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0022 0.0099
Brugia malayi RE15519p 0.0046 0.0168 0.0168
Onchocerca volvulus 0.0046 0.0168 0.0637
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Entamoeba histolytica CAAX amino terminal protease family 0.0044 0.0158 0.0487
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0067 0.0284 0.0377
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0009 0.0041
Onchocerca volvulus Putative sulfate transporter 0.0247 0.123 0.474
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Schistosoma mansoni lipoxygenase 0.0276 0.1384 0.1863
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.2033 0.274
Onchocerca volvulus 0.0046 0.0168 0.0637
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0168 0.022
Brugia malayi TAR-binding protein 0.0076 0.0332 0.0332
Onchocerca volvulus 0.0046 0.0168 0.0637
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0211 0.1043 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0044 0.0162 0.0212
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0168 0.022
Schistosoma mansoni biogenic amine receptor 0.0046 0.0168 0.022
Schistosoma mansoni microtubule-associated protein tau 0.079 0.4102 0.5536
Schistosoma mansoni hypothetical protein 0.004 0.0137 0.0179
Brugia malayi sulfakinin receptor protein 0.0046 0.0168 0.0168
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0046 0.0168 0.0168
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.086 0.1155
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0168 0.022
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0057 0.0508
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0168 0.022
Echinococcus granulosus FTZ F1 alpha 0.0479 0.2458 0.3314
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0168 0.022
Schistosoma mansoni hypothetical protein 0.0034 0.0108 0.0139
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0143 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0299 0.0398
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.1432 1
Toxoplasma gondii CAAX amino terminal protease family protein 0.0044 0.0158 0.2817
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Onchocerca volvulus 0.0046 0.0168 0.0637
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0046 0.0168 0.022
Mycobacterium leprae Probable lipase LipE 0.0041 0.0143 0.0296
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0067 0.0284 0.0888
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0051 0.0063
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0046 0.0168 0.0168
Schistosoma mansoni hypothetical protein 0.1416 0.7406 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0143 0.0628
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0067 0.0284 0.0284
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0021 0.0051
Loa Loa (eye worm) RNA binding protein 0.0076 0.0332 0.1461
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0012 0.0076
Echinococcus granulosus g protein coupled receptor 0.0046 0.0168 0.022
Echinococcus multilocularis thyroid hormone receptor alpha 0.0044 0.0162 0.0212
Brugia malayi hypothetical protein 0.0023 0.0051 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0055 0.0066
Entamoeba histolytica CAAX prenyl protease family 0.0211 0.1043 0.3301
Echinococcus granulosus neuropeptide receptor 0.0046 0.0168 0.022
Mycobacterium ulcerans glutaminase 0.0224 0.1112 0.143
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0168 0.022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0168 0.022
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0067 0.0284 0.0377
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0127
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0063 0.0186
Loa Loa (eye worm) doublecortin family protein 0.0071 0.0305 0.1343
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0168 0.022
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0006 0.0002
Toxoplasma gondii hypothetical protein 0.0044 0.0158 0.2817
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0652 0.0874
Echinococcus granulosus hypothetical protein 0.0046 0.0168 0.022
Schistosoma mansoni carbonic anhydrase 0.061 0.315 0.4249
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Schistosoma mansoni biogenic amine receptor 0.0046 0.0168 0.022
Onchocerca volvulus 0.0046 0.0168 0.0637
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0143 0.0296
Echinococcus multilocularis lipoxygenase domain containing protein 0.0071 0.0305 0.0405
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0042 0.0149 0.0195
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.0338 0.0423
Mycobacterium tuberculosis Beta-carbonic anhydrase 0.1175 0.6132 1
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Entamoeba histolytica hypothetical protein 0.0043 0.0157 0.0485
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0046 0.0168 0.022
Trypanosoma brucei Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0039 0.0135 0.1256
Loa Loa (eye worm) hypothetical protein 0.0023 0.0051 0.0226
Onchocerca volvulus Serine\/threonine kinase homolog 0.0078 0.0339 0.1299
Echinococcus granulosus ecdysone induced protein 78C 0.0044 0.0162 0.0212
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0078 0.0341 0.0437
Brugia malayi Cathepsin L-like precursor 0.0015 0.0005 0.0005
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0039 0.0135 0.0159
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0234 0.1164 0.1887
Brugia malayi follicle stimulating hormone receptor 0.0046 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0081 0.0358 0.1578
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0057 0.0508
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0083 0.0368 0.2502
Schistosoma mansoni survival motor neuron protein 0.0055 0.0219 0.029
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0042 0.0149 0.0195
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0158 0.0243
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.0583 0.3004 0.4891
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0168 0.022
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0083 0.0368 0.0472
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0038 0.0038
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0044 0.0161 0.0211
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0044 0.0158 0.0243
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0046 0.0168 0.0168
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0022 0.0024
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.0038 0.0045
Echinococcus multilocularis allatostatin A receptor 0.0046 0.0168 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0005 0.0005
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.0312 0.1578 0.2563
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0105 0.0105
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0284 0.0363
Loa Loa (eye worm) hypothetical protein 0.0041 0.0143 0.0628
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0044 0.0162 0.0713
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Leishmania major carbonic anhydrase family protein, putative 0.061 0.315 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0044 0.0162 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0063 0.0041
Mycobacterium ulcerans integral membrane transporter 0.0039 0.0135 0.0159
Brugia malayi hypothetical protein 0.0071 0.0305 0.0305
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0108 0.0991
Loa Loa (eye worm) hypothetical protein 0.003 0.0088 0.0386
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0146 0.0697 0.307
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0034 0.0108 0.0992
Trypanosoma brucei Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0016 0.0011 0.0059
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0168 0.022
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.03 0.1324
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0067 0.0284 0.1912
Onchocerca volvulus 0.0055 0.0219 0.0835
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0034 0.0108 0.0139
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0046 0.0168 0.0741
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.1432 0.4539
Treponema pallidum hypothetical protein 0.0234 0.1164 0.7957
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0168 0.0741
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0021 0.0051
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0127
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0034 0.0108 0.0139
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0029 0.0033
Echinococcus granulosus 7tm_1 domain containing protein 0.0046 0.0168 0.022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0038 0.0045
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0121 0.0183
Onchocerca volvulus 0.0046 0.0168 0.0637
Brugia malayi hypothetical protein 0.0271 0.1358 0.1358
Onchocerca volvulus 0.0015 0.0005 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0168 0.022
Echinococcus granulosus microtubule associated protein 2 0.079 0.4102 0.5536
Brugia malayi Fli-1 protein 0.0214 0.1059 0.1059
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Echinococcus multilocularis lipoxygenase domain containing protein 0.0071 0.0305 0.0405
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0121 0.037
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0009 0.0041
Plasmodium falciparum flap endonuclease 1 0.0025 0.0062 0.0489
Brugia malayi G-protein coupled receptor 0.0046 0.0168 0.0168
Mycobacterium tuberculosis Possible penicillin-binding protein 0.026 0.1301 0.211
Onchocerca volvulus 0.0071 0.0305 0.1165
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0078 0.0339 0.0452
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0061 0.0247 0.209
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0009 0.0005
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0168 0.022
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0121 0.0533
Schistosoma mansoni hypothetical protein 0.004 0.0137 0.0179
Brugia malayi Cytochrome P450 family protein 0.0046 0.0169 0.0169
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0083 0.0368 0.3129
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0031 0.0036
Schistosoma mansoni zinc finger protein 0.0018 0.0021 0.0021
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0059 0.0073
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0054 0.021 0.0655
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0052 0.0201 0.0265
Leishmania major cathepsin L-like protease 0.0056 0.0222 0.0692
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0059 0.0258
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0332 0.0332
Entamoeba histolytica CAAX amino terminal protease family 0.0044 0.0158 0.0487
Giardia lamblia GTOR 0.0018 0.0021 0.0057
Echinococcus granulosus sex peptide receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0109 0.0501 0.2208
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0067 0.0284 0.0888
Brugia malayi CXXC zinc finger family protein 0.0028 0.0075 0.0075
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.031 0.031
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0055 0.0068
Mycobacterium ulcerans putative regulatory protein 0.0032 0.0094 0.0106
Echinococcus granulosus lamin dm0 0.0031 0.0091 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0168 0.022
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0143 0.0218
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0022 0.0172
Onchocerca volvulus 0.0015 0.0005 0.0007
Mycobacterium tuberculosis Probable integral membrane protein 0.0044 0.0158 0.0243
Echinococcus granulosus g-protein coupled receptor 0.0046 0.0168 0.022
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0077 0.0332 0.1608
Schistosoma mansoni hypothetical protein 0.0043 0.0157 0.0205
Brugia malayi intermediate filament protein 0.0031 0.0091 0.0091
Leishmania major DNA damage repair protein, putative 0.0016 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0165
Onchocerca volvulus 0.0046 0.0168 0.0637
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0697 0.0934
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0168 0.022
Schistosoma mansoni intermediate filament proteins 0.0031 0.0091 0.0116
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0038 0.0045
Schistosoma mansoni amine GPCR 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0108 0.1892
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.0071 0.0304 0.2886
Brugia malayi bHLH-PAS transcription factor 0.0032 0.0094 0.0094
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0157 0.0205
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0339 0.0435
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0108 0.0885
Brugia malayi larval opioid receptor 0.0046 0.0168 0.0168
Mycobacterium ulcerans hypothetical protein 0.0044 0.0158 0.0189
Onchocerca volvulus 0.0046 0.0168 0.0637
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0134 0.0413
Loa Loa (eye worm) melatonin receptor type 1A 0.0046 0.0168 0.0741
Echinococcus granulosus g protein coupled receptor 0.0046 0.0168 0.022
Leishmania major protein kinase A catalytic subunit 0.0042 0.0149 0.0459
Brugia malayi jmjC domain containing protein 0.0067 0.0283 0.0283
Brugia malayi Cathepsin L-like precursor 0.0015 0.0005 0.0005
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0015 0.0005 0.0022
Trypanosoma cruzi ISWI complex protein 0.0018 0.0021 0.0155
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0044 0.0161 0.071
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0035 0.0154
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0168 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.149 0.1929
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0044 0.0162 0.0162
Schistosoma mansoni hypothetical protein 0.0024 0.0053 0.0065
Brugia malayi Serotonin receptor 0.0046 0.0168 0.0168
Onchocerca volvulus 0.0046 0.0168 0.0637
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0034 0.0108 0.0328
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0041 0.0145 0.0639
Trypanosoma cruzi DNA polymerase eta, putative 0.0016 0.0012 0.0076
Brugia malayi Doublecortin family protein 0.0071 0.0305 0.0305
Giardia lamblia Kinase, AGC PKA 0.0042 0.0149 0.0962
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.015 0.1403
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0047 0.0174 0.0765
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0063 0.0066
Trypanosoma cruzi major cysteine proteinase, putative 0.0044 0.0159 0.1489
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0067 0.0284 0.2407
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0042 0.0051
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0168 0.022
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0021 0.0038 0.0038
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0162 0.0162
Loa Loa (eye worm) Carm1-pending protein 0.0034 0.0108 0.0474
Loa Loa (eye worm) steroid hormone receptor 0.0044 0.0162 0.0713
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0149 0.0195
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0177 0.086 0.379
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Brugia malayi glutaminase DH11.1 0.0224 0.1112 0.1112
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0222 0.2097
Schistosoma mansoni hypothetical protein 0.0046 0.0168 0.022
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0038 0.0045
Entamoeba histolytica cysteine proteinase, putative 0.0015 0.0005 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0284 0.0363
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0276 0.1384 0.1863
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0038 0.0045
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.0235 0.0733
Schistosoma mansoni growth hormone secretagogue receptor 0.0046 0.0168 0.022
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0012 0.0076
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0168 0.022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0071 0.0305 0.1343
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0168 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0042 0.0149 0.1243
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0044 0.0162 0.0212
Trypanosoma brucei CAAX amino terminal protease, putative 0.0211 0.1043 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.1432 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0021 0.0154
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0091 0.04
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0063 0.0186
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0021 0.0154
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0108 0.0991
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0055 0.0068
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0031 0.0036
Schistosoma mansoni transcription factor btf3 0.0034 0.0108 0.0139
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0021 0.0051
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0062 0.0549
Plasmodium vivax JmjC domain containing protein 0.0018 0.0022 0.0151
Trypanosoma cruzi DNA polymerase eta, putative 0.0052 0.0201 0.1895
Schistosoma mansoni cpg binding protein 0.0032 0.0095 0.0122
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0052 0.0201 0.0265
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0084 0.037 0.0493
Brugia malayi beta-lactamase family protein 0.0041 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0095 0.0427 0.1344
Onchocerca volvulus 0.0046 0.0168 0.0637
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1432 0.1854
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0339 0.0452
Trypanosoma brucei Histone methylation protein DOT1, putative 0.0016 0.0011 0.0059
Echinococcus granulosus CAAX prenyl protease 2 0.0211 0.1043 0.1402
Loa Loa (eye worm) hypothetical protein 0.0109 0.0501 0.2208
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Leishmania major cysteine peptidase A (CPA) 0.0015 0.0005 0.0001
Giardia lamblia Kinase, PLK 0.0078 0.0339 0.2303
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0042 0.0149 0.1391
Echinococcus granulosus orexin receptor type 2 0.0046 0.0168 0.022
Entamoeba histolytica hypothetical protein 0.0095 0.0427 0.1344
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0038 0.0321
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0143 0.0169
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0021 0.0021
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0023 0.005 0.006
Leishmania major histone-lysine N-methyltransferase, putative 0.0016 0.0011 0.002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0445 0.1961
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0044 0.0161 0.071
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0547 0.0733
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0121 0.1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0256 0.1126
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0038 0.0321
Onchocerca volvulus 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0434 0.058
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Trypanosoma brucei histone-lysine n-methyltransferase 0.0016 0.0011 0.0059
Loa Loa (eye worm) AGC/PKA protein kinase 0.0042 0.0149 0.0657
Onchocerca volvulus 0.0064 0.0266 0.1016
Loa Loa (eye worm) hypothetical protein 0.0271 0.1358 0.5986
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0042 0.0149 0.1391
Echinococcus granulosus neuropeptide receptor A26 0.0046 0.0168 0.022
Onchocerca volvulus 0.0031 0.0091 0.0338
Loa Loa (eye worm) hypothetical protein 0.0137 0.0649 0.2862
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0062 0.0271
Plasmodium falciparum LCCL domain-containing protein 0.0071 0.0305 0.2586
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0062 0.0074
Brugia malayi Flap endonuclease-1 0.0025 0.0062 0.0062
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0162 0.0212
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0051 0.0063
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0067 0.0284 0.5146
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0303 0.1337
Brugia malayi bZIP transcription factor family protein 0.0106 0.0485 0.0485
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0044 0.0162 0.0713
Echinococcus multilocularis neuropeptide receptor A26 0.0046 0.0168 0.022
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0022 0.0099
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0105 0.0135
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0445 0.0594
Onchocerca volvulus 0.0015 0.0005 0.0007
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0083 0.0368 0.0472
Schistosoma mansoni zinc finger protein 0.0021 0.0038 0.0045
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0034 0.0108 0.0992
Echinococcus granulosus cpg binding protein 0.0032 0.0095 0.0122
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0234 0.1164 1
Schistosoma mansoni kinase 0.004 0.0138 0.018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0162 0.0212
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0067 0.0284 0.2691
Schistosoma mansoni hypothetical protein 0.0018 0.0021 0.0021
Loa Loa (eye worm) glutaminase 0.0224 0.1112 0.4902
Brugia malayi serine/threonine-protein kinase plk-2 0.0078 0.0339 0.0339
Mycobacterium ulcerans hypothetical protein 0.0131 0.062 0.079
Echinococcus multilocularis Smad4 0.0025 0.0059 0.0073
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0051 0.006
Echinococcus granulosus intermediate filament protein 0.0031 0.0091 0.0116
Schistosoma mansoni ap endonuclease 0.0037 0.0121 0.0157
Schistosoma mansoni hypothetical protein 0.0046 0.0168 0.022
Brugia malayi Bromodomain containing protein 0.0088 0.0392 0.0392
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0054 0.021 0.0329
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0046 0.0168 0.0168
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0029 0.0207
Loa Loa (eye worm) hypothetical protein 0.0044 0.0162 0.0713
Schistosoma mansoni smad1 5 8 and 0.0025 0.0059 0.0073
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0663 0.1068
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0168 0.022
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0038 0.0045
Loa Loa (eye worm) MH2 domain-containing protein 0.0364 0.1851 0.8159
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0134 0.0169
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0009 0.0039
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0121 0.0121
Brugia malayi tailless protein 0.0021 0.0038 0.0038
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.0235 0.037
Trypanosoma brucei chrX additional, unordered contigs 0.0016 0.0012 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0953 0.1231
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0063 0.0066
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0252
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Loa Loa (eye worm) hypothetical protein 0.0096 0.0434 0.1914
Loa Loa (eye worm) hypothetical protein 0.0072 0.031 0.1368
Echinococcus multilocularis serotonin receptor 0.0046 0.0168 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0062 0.0181
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0108 0.0327
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0044 0.0161 0.0203
Plasmodium vivax sulfate transporter, putative 0.0039 0.0135 0.1122
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.005 0.0191 0.3441
Entamoeba histolytica deoxycytidyl transferase, putative 0.0052 0.0201 0.0625
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0059 0.0258
Onchocerca volvulus 0.0046 0.0168 0.0637
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0162 0.0212
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0051 0.006
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0168 0.022
Schistosoma mansoni jumonji domain containing protein 0.0067 0.0283 0.0376
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0078 0.0338 0.0433
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0133 0.0166
Trypanosoma brucei ISWI complex protein 0.0018 0.0021 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Brugia malayi ImpB/MucB/SamB family protein 0.0052 0.0201 0.0201
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0022 0.0172
Brugia malayi MH1 domain containing protein 0.0025 0.0059 0.0059
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0083 0.0368 0.0472
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.0078 0.0341 0.1502
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0038 0.0168
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0121 0.112
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.149 0.1929
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0023 0.005 0.005
Echinococcus granulosus survival motor neuron protein 1 0.0271 0.1358 0.1828
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0341 0.0454
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0121 0.112
Trypanosoma brucei DNA polymerase eta, putative 0.0052 0.0201 0.1895
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0038 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0012 0.0076
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.021 0.021
Trichomonas vaginalis conserved hypothetical protein 0.1472 0.7704 1
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0168 0.022
Plasmodium vivax DNA repair protein REV1, putative 0.0016 0.0012 0.0066
Loa Loa (eye worm) hypothetical protein 0.0044 0.0162 0.0713
Leishmania major basic transcription factor 3a, putative 0.0034 0.0108 0.0327
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0023 0.0024
Brugia malayi Papain family cysteine protease containing protein 0.0015 0.0005 0.0005
Echinococcus granulosus neuropeptide s receptor 0.0046 0.0168 0.022
Echinococcus multilocularis CAAX prenyl protease 2 0.0211 0.1043 0.1402
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0062 0.0181
Echinococcus multilocularis RUN 0.0071 0.0305 0.0405
Brugia malayi ecdysone receptor 0.0021 0.0038 0.0038
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0234 0.1164 1
Onchocerca volvulus 0.0504 0.2592 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0063 0.0186
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0145 0.0189
Brugia malayi CHE-14 protein 0.0041 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Brugia malayi nuclear receptor NHR-67 0.0021 0.0038 0.0038
Onchocerca volvulus 0.008 0.0348 0.1333
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0134 0.0413
Echinococcus multilocularis lysine specific demethylase 5A 0.0067 0.0283 0.0376
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0054 0.021 0.0278
Echinococcus granulosus protein arginine methyltransferase 0.0061 0.0247 0.0327
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0044 0.0162 0.0713
Schistosoma mansoni lamin 0.0031 0.0091 0.0116
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0067 0.0284 0.2691
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0038 0.0045
Entamoeba histolytica cysteine protease, putative 0.0015 0.0005 0.0001
Leishmania major DNA polymerase kappa, putative 0.0058 0.0235 0.0733
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0134 0.0169
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0146 0.0191
Schistosoma mansoni polycystin 1-related 0.0071 0.0305 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0044 0.0162 0.0713
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0143 0.0169
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0025 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0445 0.0594
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0168 0.022
Echinococcus granulosus phd:f box containing protein 0.0018 0.0022 0.0024
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0042 0.0149 0.1391
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Echinococcus multilocularis protein arginine methyltransferase 0.0061 0.0247 0.0327
Schistosoma mansoni calcium-activated potassium channel 0.0138 0.0657 0.0881
Loa Loa (eye worm) hypothetical protein 0.0023 0.0051 0.0226
Loa Loa (eye worm) hypothetical protein 0.0146 0.0697 0.307
Brugia malayi MH2 domain containing protein 0.0025 0.0059 0.0059
Schistosoma mansoni lipoxygenase 0.0147 0.0705 0.0946
Mycobacterium tuberculosis Conserved hypothetical protein 0.0052 0.0201 0.0314
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0046 0.0168 0.022
Toxoplasma gondii AGC kinase 0.0042 0.0149 0.2658
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0108 0.0474
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0016 0.0011 0.0059
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0095 0.0427 0.4072
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0057 0.0508
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0149 0.0188
Echinococcus multilocularis ecdysone induced protein 78C 0.0044 0.0162 0.0212
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0235 0.2222
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0284 0.2691
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0134 0.0169
Echinococcus multilocularis small conductance calcium activated potassium 0.0138 0.0657 0.0881
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0162 0.0212
Entamoeba histolytica carbonic anhydrase, putative 0.061 0.315 1
Schistosoma mansoni DNA polymerase IV / kappa 0.0016 0.0012 0.001
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Onchocerca volvulus 0.0021 0.0038 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0145 0.0182
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0332 0.1461
Entamoeba histolytica serine/threonine protein kinase, putative 0.0078 0.0339 0.1065
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0168 0.022
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0168 0.022
Schistosoma mansoni histone J3 methyltransferase 0.0124 0.0583 0.0781
Loa Loa (eye worm) hypothetical protein 0.0211 0.1043 0.4596
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0012 0.0076
Onchocerca volvulus 0.0102 0.0467 0.1791
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0091 0.0091
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0067 0.0284 0.0888
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0234 0.1164 0.1497
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0108 0.0885
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.015 0.1403
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0067 0.0284 0.1244
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0445 0.0594
Onchocerca volvulus 0.0046 0.0168 0.0637
Mycobacterium ulcerans hypothetical protein 0.0026 0.0063 0.0066
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0044 0.0161 0.1505
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0053 0.0234
Echinococcus multilocularis somatostatin receptor 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Trichomonas vaginalis glucosylceramidase, putative 0.0296 0.149 0.1929
Brugia malayi jmjC domain containing protein 0.0071 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0051 0.0195 0.0862
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0038 0.0168
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.002
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0059 0.0073
Brugia malayi jmjC domain containing protein 0.0018 0.0022 0.0022
Trichomonas vaginalis glutaminase, putative 0.0224 0.1112 0.1439
Echinococcus multilocularis musashi 0.0031 0.0091 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0168 0.022
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0038 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0145 0.0189
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0021 0.0051
Schistosoma mansoni hypothetical protein 0.0046 0.0168 0.022
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0211 0.1043 1
Leishmania major hypothetical protein, conserved 0.0018 0.0022 0.0057
Leishmania major cathepsin L-like protease 0.0015 0.0005 0.0001
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0022 0.0024
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0034 0.0108 0.0134
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0105 0.0462
Leishmania major hypothetical protein, conserved 0.0018 0.0021 0.0051
Loa Loa (eye worm) hypothetical protein 0.0042 0.0149 0.0658
Echinococcus multilocularis dna polymerase eta 0.0052 0.0201 0.0265
Leishmania major cathepsin L-like protease 0.0015 0.0005 0.0001
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0042 0.0149 0.0195
Brugia malayi Cathepsin L-like precursor 0.0015 0.0005 0.0005
Echinococcus granulosus lipoxygenase domain containing protein 0.0071 0.0305 0.0405
Schistosoma mansoni opsin-like receptor 0.0046 0.0168 0.022
Echinococcus multilocularis microtubule associated protein 2 0.079 0.4102 0.5536
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0332 0.0441
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0044 0.0162 0.0212
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Schistosoma mansoni steroid hormone receptor ad4bp 0.0044 0.0162 0.0212
Echinococcus multilocularis cpg binding protein 0.0032 0.0095 0.0122
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0095 0.0427 0.4072
Echinococcus multilocularis GPCR, family 2 0.0034 0.0105 0.0135
Chlamydia trachomatis sulfate transporter 0.0039 0.0135 0.3505
Loa Loa (eye worm) hypothetical protein 0.0021 0.0038 0.0168
Schistosoma mansoni hypothetical protein 0.0138 0.0657 0.0881
Echinococcus multilocularis transfer RNA-Lys 0.0032 0.0094 0.012
Leishmania major cathepsin L-like protease 0.0015 0.0005 0.0001
Schistosoma mansoni hypothetical protein 0.0055 0.0219 0.029
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0021 0.0021
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0143 0.0186
Schistosoma mansoni DNA polymerase eta 0.0052 0.0201 0.0265
Echinococcus granulosus 7TM GPCR rhodopsin 0.0046 0.0168 0.022
Brugia malayi Dopamine receptor protein 1 0.0046 0.0168 0.0168
Brugia malayi PAS domain containing protein 0.0043 0.0152 0.0152
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0106 0.0485 0.0649
Trypanosoma cruzi histone-lysine N-methyltransferase, putative 0.0016 0.0011 0.0059
Schistosoma mansoni hypothetical protein 0.0034 0.0105 0.0135
Brugia malayi Carm1-pending protein 0.0034 0.0108 0.0108
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0077 0.0332 0.315
Echinococcus multilocularis lamin dm0 0.0031 0.0091 0.0116
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1432 0.1854
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0042 0.0149 0.0195
Loa Loa (eye worm) fibroinase 0.0015 0.0005 0.0022
Echinococcus granulosus lysosomal alpha glucosidase 0.0177 0.086 0.1155
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0038 0.0045
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0057 0.0452
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0445 0.0445
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0063 0.0089
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0014
Brugia malayi Steroid receptor seven-up type 2 0.0044 0.0162 0.0162
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0303 0.0403
Plasmodium falciparum DNA repair protein REV1, putative 0.0016 0.0012 0.0066
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0062 0.0549
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0044 0.0162 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0044 0.0162 0.0713
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0038 0.0135
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0145 0.0189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0168 0.022
Schistosoma mansoni calcium-activated potassium channel 0.0131 0.0621 0.0833
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1432 0.1854
Echinococcus granulosus neuropeptide receptor 0.0046 0.0168 0.022
Schistosoma mansoni glutaminase 0.0224 0.1112 0.1496
Schistosoma mansoni smad 0.0025 0.0059 0.0073
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0266 0.0353
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0284 0.0363
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0134 0.0169
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0009 0.0041
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0134 0.0592
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0117 0.0547 0.0733
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0027 0.0068 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0056 0.0222 0.2097
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0043 0.0157 0.0485
Brugia malayi beta-NAC-like protein 0.0034 0.0108 0.0108
Schistosoma mansoni Smad4 0.0025 0.0059 0.0073
Onchocerca volvulus Protein ultraspiracle homolog 0.0044 0.0162 0.0613
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0143 0.0186
Brugia malayi nuclear receptor RXR 0.0023 0.0051 0.0051
Schistosoma mansoni alpha-glucosidase 0.0152 0.073 0.098
Echinococcus multilocularis neuropeptide s receptor 0.0046 0.0168 0.022
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0046 0.0168 0.0637
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0042 0.0149 0.1391
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0021 0.0154
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0046 0.0168 0.022
Onchocerca volvulus 0.0071 0.0305 0.1165
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0332 0.1461
Toxoplasma gondii inorganic anion transporter, sulfate permease (SulP) family protein 0.0039 0.0135 0.24
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0012 0.0076
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0022 0.0024
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0012 0.0076
Mycobacterium tuberculosis Conserved protein 0.0041 0.0143 0.0218
Trypanosoma brucei polo-like protein kinase 0.0078 0.0339 0.3225
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0445 0.0594
Entamoeba histolytica hypothetical protein 0.0024 0.0055 0.0161
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0009 0.0005
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0211 0.1043 0.1402
Brugia malayi nuclear hormone receptor 0.0021 0.0038 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0149 0.1395
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0044 0.0162 0.0162
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0137 0.0649 0.0871
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0012 0.0076
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0162 0.0212
Schistosoma mansoni hypothetical protein 0.0071 0.0305 0.0405
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0339 0.0435
Toxoplasma gondii AGC kinase 0.0042 0.0149 0.2658
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0022 0.0024
Toxoplasma gondii hypothetical protein 0.0044 0.0158 0.2817
Schistosoma mansoni gabp alpha 0.0071 0.03 0.0399
Schistosoma mansoni neuropeptide f receptor 76f 0.0046 0.0168 0.022
Onchocerca volvulus 0.0041 0.0143 0.0539
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0168 0.0741
Schistosoma mansoni hypothetical protein 0.004 0.0137 0.0179
Leishmania major arginine N-methyltransferase, type I 0.0034 0.0108 0.0328
Echinococcus granulosus histone h3 methyltransferase 0.0124 0.0583 0.0781
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0063 0.0066
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0168 0.022
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0022 0.0323
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0038 0.0168
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0067 0.0284 0.2691
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0021 0.0154
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0042 0.0149 0.1391
Brugia malayi nuclear receptor NHR-88 0.0021 0.0038 0.0038
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0039 0.0135 0.1256
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0143 0.0179
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0042 0.0149 0.0149
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0077 0.0332 1
Echinococcus granulosus GPCR family 2 0.0034 0.0105 0.0135
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0021 0.0038 0.0321
Brugia malayi hypothetical protein 0.0046 0.0168 0.0168
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0332 0.0441
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0109 0.0501 0.067
Plasmodium vivax protease, putative 0.0044 0.0158 0.1318
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0332 0.0441
Echinococcus multilocularis dna polymerase kappa 0.0078 0.0338 0.045
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0169 0.0746
Brugia malayi hypoxia-induced factor 1 0.0132 0.0623 0.0623
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0168 0.022
Loa Loa (eye worm) hypothetical protein 0.0041 0.0143 0.0628
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0134 0.125
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0044 0.0162 0.0613
Schistosoma mansoni smad1 5 8 and 0.0025 0.0059 0.0073
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0051 0.0197 0.1851
Leishmania major cathepsin L-like protease 0.0056 0.0222 0.0692
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0338 0.3213
Onchocerca volvulus 0.0247 0.123 0.474
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0021 0.0021
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0057 0.0452
Loa Loa (eye worm) hypothetical protein 0.0046 0.0168 0.0741
Schistosoma mansoni protein arginine n-methyltransferase 0.0034 0.0108 0.0139
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0105 0.0135
Onchocerca volvulus 0.0046 0.0168 0.0637
Brugia malayi photoreceptor-specific nuclear receptor 0.0044 0.0162 0.0162
Toxoplasma gondii hypothetical protein 0.0016 0.0011 0.0108
Echinococcus granulosus Smad4 0.0025 0.0059 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0143 0.1328
Echinococcus granulosus tachykinin peptides receptor 99D 0.0046 0.0168 0.022
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0046 0.0168 0.022
Schistosoma mansoni hypothetical protein 0.0046 0.0168 0.022
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0025 0.0061 0.0548
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0067 0.0284 0.0377
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0099
Brugia malayi PHD-finger family protein 0.003 0.0088 0.0088
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0038 0.0045

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.17 uM Inhibitory activity against soybean 1-lipoxygenase (SLO) ChEMBL. 12036375
IC50 (binding) = 0.17 uM Inhibitory activity against soybean 1-lipoxygenase (SLO) ChEMBL. 12036375
IC50 (binding) = 0.25 uM Inhibitory activity against human reticulocyte 15-lipoxygenase (15-HLO) ChEMBL. 12036375
IC50 (binding) = 0.25 uM Inhibitory activity against human reticulocyte 15-lipoxygenase (15-HLO) ChEMBL. 12036375
IC50 (binding) = 14 uM Inhibitory activity against human platelet 12-lipoxygenase (12-HLO) ChEMBL. 12036375
IC50 (binding) = 14 uM Inhibitory activity against human platelet 12-lipoxygenase (12-HLO) ChEMBL. 12036375
IC50 (functional) = 25.03 uM Inhibitory activity of the compound against HIV Tat-regulated Transactivation in COS cells. ChEMBL. 9685238
Inhibition (functional) = 7.3 % Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 3 uM. ChEMBL. 9685238
Inhibition (functional) = 9 % Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 1 uM. ChEMBL. 9685238
Inhibition (functional) = 20.7 % Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 10 uM. ChEMBL. 9685238
Inhibition (functional) = 38.5 % Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 20 uM. ChEMBL. 9685238
Inhibition (functional) = 56.3 % Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 30 uM. ChEMBL. 9685238
Inhibition (functional) = 83.3 % Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 60 uM. ChEMBL. 9685238
Inhibition (functional) = 92.3 % Compound tested for inhibition of HIV Tat-regulated Transactivation in COS cells at a concentration of 100 uM. ChEMBL. 9685238

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.