Detailed information for compound 1497178

Basic information

Technical information
  • TDR Targets ID: 1497178
  • Name: 2-(4-methyl-2-methylsulfanyl-6-oxo-3H-pyrimid in-5-yl)ethyl benzoate
  • MW: 304.364 | Formula: C15H16N2O3S
  • H donors: 1 H acceptors: 4 LogP: 3.23 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1nc(C)c(c(n1)O)CCOC(=O)c1ccccc1
  • InChi: 1S/C15H16N2O3S/c1-10-12(13(18)17-15(16-10)21-2)8-9-20-14(19)11-6-4-3-5-7-11/h3-7H,8-9H2,1-2H3,(H,16,17,18)
  • InChiKey: VLGHIWNOYMSVED-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • benzoic acid 2-[4-methyl-2-(methylthio)-6-oxo-3H-pyrimidin-5-yl]ethyl ester
  • benzoic acid 2-[4-keto-6-methyl-2-(methylthio)-1H-pyrimidin-5-yl]ethyl ester
  • SMR000168635
  • 2N-732
  • ZINC04002888
  • 2-[4-methyl-2-(methylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]ethyl benzenecarboxylate
  • MLS000331252

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 cytochrome P450, family 2, subfamily C, polypeptide 9 490 aa 441 aa 21.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.122 0.1469
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0081 0.0414 0.0435
Giardia lamblia Kinase, AGC PKA 0.0155 0.1195 0.4978
Echinococcus granulosus serine/threonine protein kinase 0.0164 0.1286 0.1283
Loa Loa (eye worm) hypothetical protein 0.0134 0.0972 0.1039
Entamoeba histolytica receptor protein kinase, putative 0.0046 0.0039 0.0048
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0081 0.0414 0.0411
Loa Loa (eye worm) AGC/PKN protein kinase 0.0291 0.264 0.2845
Echinococcus multilocularis protein kinase shaggy 0.0227 0.1963 0.2366
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0064 0.0228 0.0376
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1998 0.3803
Leishmania major hypothetical protein, conserved 0.0046 0.0039 0.0108
Trypanosoma cruzi casein kinase, putative 0.0109 0.0703 0.2936
Brugia malayi phosphoinositide-dependent protein kinase I 0.0082 0.0424 0.0444
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0194 0.1612 0.2858
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0039 0.0043
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0509 0.088
Loa Loa (eye worm) hypothetical protein 0.0095 0.0558 0.059
Brugia malayi map kinase activated protein kinase protein 2 0.0384 0.363 0.3917
Trypanosoma cruzi casein kinase, putative 0.0109 0.0703 0.2936
Entamoeba histolytica hypothetical protein 0.0046 0.0039 0.0048
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0162 0.016
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0109 0.0162
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0084 0.0441 0.0464
Entamoeba histolytica protein kinase, putative 0.0044 0.0018 0.001
Schistosoma mansoni shc transforming protein 0.0055 0.0136 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0144 0.108 0.1905
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0055 0.0136 0.026
Trichomonas vaginalis STE family protein kinase 0.0087 0.047 0.0811
Loa Loa (eye worm) protein kinase domain-containing protein 0.0046 0.0039 0.0029
Toxoplasma gondii histone kinase SNF1, putative 0.009 0.0505 0.1599
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0113 0.0753 0.08
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Schistosoma mansoni protein kinase 0.0453 0.4361 0.8335
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.008 0.0398 0.0394
Brugia malayi Protein kinase domain containing protein 0.0152 0.1164 0.1246
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0044 0.0018 0.0018
Toxoplasma gondii AGC kinase 0.0285 0.2578 0.8348
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Brugia malayi intracellular kinase 0.0227 0.1963 0.2111
Echinococcus granulosus dual specificity protein kinase clk2 0.0152 0.1164 0.1161
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0703 0.1318
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0505 0.094
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0039 0.0029
Echinococcus multilocularis expressed protein 0.0084 0.0441 0.0527
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0044 0.0018 0.0016
Echinococcus multilocularis casein kinase ii subunit alpha 0.01 0.0615 0.0738
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0039 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0039 0.0029
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0227 0.1963 0.831
Entamoeba histolytica protein kinase, putative 0.0091 0.0514 0.0898
Brugia malayi Protein kinase domain containing protein 0.0278 0.2498 0.269
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0183 0.1494 0.149
Brugia malayi Variant SH3 domain containing protein 0.0096 0.0565 0.0597
Toxoplasma gondii protein kinase 0.0046 0.0039 0.0083
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0046 0.0039 0.0043
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0113 0.0747 0.2762
Echinococcus multilocularis tyrosine protein kinase Blk 0.0186 0.1528 0.1841
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0039 0.0036
Loa Loa (eye worm) thyroid receptor interactor 0.0113 0.0748 0.0797
Echinococcus multilocularis rho associated protein kinase 0.0318 0.2922 0.3523
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0238 0.2072 0.2069
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0384 0.363 0.4378
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0039 0.0048
Loa Loa (eye worm) TK protein kinase 0.0186 0.1528 0.1642
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.0675 0.081
Echinococcus granulosus contactin 0.0054 0.012 0.0116
Onchocerca volvulus 0.0072 0.031 0.0591
Trichomonas vaginalis AGC family protein kinase 0.0144 0.108 0.1905
Schistosoma mansoni SH2A 0.0055 0.0136 0.0232
Brugia malayi STE20-like kinase MST 0.0252 0.2222 0.2392
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Echinococcus granulosus rho-associated protein kinase 1 0.0318 0.2922 0.292
Loa Loa (eye worm) TK/FER protein kinase 0.0101 0.0627 0.0665
Echinococcus granulosus thioredoxin glutathione reductase 0.0044 0.002 0.0016
Echinococcus multilocularis serine:threonine kinase SAD 1 0.009 0.0505 0.0605
Echinococcus granulosus integrin alpha 3 0.0115 0.0769 0.0766
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0227 0.1963 0.3736
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0747 0.0898
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Schistosoma mansoni tensin 0.0055 0.0136 0.0232
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0505 0.185
Brugia malayi Protein kinase domain containing protein 0.0063 0.0223 0.0226
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus granulosus tyrosine protein kinase Srms 0.0495 0.4807 0.4805
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0138 0.1014 0.3763
Loa Loa (eye worm) TK/EGFR protein kinase 0.0448 0.4304 0.4647
Toxoplasma gondii AGC kinase 0.0113 0.0747 0.2388
Brugia malayi protein kinase C II. 0.0207 0.1752 0.1883
Entamoeba histolytica hypothetical protein 0.0046 0.0042 0.0054
Echinococcus granulosus fibroblast growth factor receptor 4 0.0238 0.2072 0.2069
Brugia malayi Hr1 repeat family protein 0.0291 0.264 0.2844
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Trypanosoma brucei casein kinase I, isoform 2 0.0109 0.0703 0.2593
Echinococcus granulosus casein kinase I alpha 0.0109 0.0703 0.0699
Brugia malayi Fibronectin type III domain containing protein 0.0096 0.0565 0.0597
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Loa Loa (eye worm) thioredoxin reductase 0.0044 0.0014 0.0002
Echinococcus granulosus Glutaredoxin protein 5 0.012 0.0823 0.082
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.0946 0.1137
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0613 0.6063 0.6552
Plasmodium falciparum protein kinase, putative 0.0046 0.0039 0.0054
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0144 0.1074 0.107
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0046 0.0039 0.0043
Echinococcus multilocularis roundabout 2 0.0054 0.012 0.014
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.236 0.4199
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0162 0.1271 0.153
Trichomonas vaginalis CAMK family protein kinase 0.0213 0.1813 0.3219
Echinococcus multilocularis roundabout 2 0.0054 0.012 0.014
Echinococcus multilocularis aurora kinase A 0.0144 0.108 0.13
Echinococcus granulosus mitogen activated protein kinase 11 0.0157 0.122 0.1217
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0081 0.0414 0.0496
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0424 0.0728
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0053 0.0109 0.0357
Trypanosoma brucei cdc2-related kinase 1 0.0118 0.0807 0.2985
Brugia malayi Protein kinase domain containing protein 0.0389 0.3683 0.3974
Entamoeba histolytica hypothetical protein 0.0046 0.0039 0.0048
Entamoeba histolytica protein kinase domain containing protein 0.0082 0.0417 0.0725
Plasmodium falciparum tyrosine kinase-like protein 0.0046 0.0039 0.0054
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Echinococcus granulosus SH2 domain containing protein 7 0.0055 0.0136 0.0133
Onchocerca volvulus 0.0482 0.467 0.8908
Onchocerca volvulus 0.0062 0.0205 0.0392
Echinococcus granulosus hypothetical protein 0.0055 0.0136 0.0133
Entamoeba histolytica protein kinase, putative 0.0087 0.047 0.0821
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0046 0.0039 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.236 0.4199
Entamoeba histolytica receptor protein kinase, putative 0.0046 0.0039 0.0048
Echinococcus multilocularis integrin alpha ps 0.0067 0.0262 0.0312
Onchocerca volvulus 0.0079 0.0389 0.0742
Giardia lamblia Kinase, NEK 0.0135 0.0984 0.4073
Schistosoma mansoni protein kinase 0.0232 0.2011 0.3828
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0747 0.3127
Schistosoma mansoni glucose transport protein 0.0106 0.0675 0.1265
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0082 0.0419 0.1319
Schistosoma mansoni ste20-related kinase 0.0202 0.1692 0.3216
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0056 0.0149 0.0146
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0615 0.107
Schistosoma mansoni atypical protein kinase C 0.0292 0.2652 0.5057
Toxoplasma gondii facilitative glucose transporter GT1 0.0106 0.0675 0.2151
Trypanosoma brucei protein kinase, putative 0.0085 0.0447 0.1631
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0084 0.0441 0.1819
Echinococcus granulosus tensin 0.0055 0.0136 0.0133
Entamoeba histolytica PH domain containing protein kinase, putative 0.0164 0.1286 0.2282
Echinococcus multilocularis SH2 motif 0.0055 0.0136 0.016
Echinococcus multilocularis ephrin type A receptor 4 A 0.0108 0.0696 0.0835
Entamoeba histolytica protein kinase, putative 0.0144 0.108 0.1913
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0969 0.1828
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0046 0.0039 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0144 0.108 0.1905
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0039 0.0029
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0842 0.353
Loa Loa (eye worm) hypothetical protein 0.0044 0.0019 0.0007
Loa Loa (eye worm) TK/CSK protein kinase 0.0046 0.0039 0.0029
Echinococcus multilocularis protein kinase c epsilon type 0.0207 0.1752 0.2111
Loa Loa (eye worm) hypothetical protein 0.0138 0.1013 0.1084
Leishmania major protein kinase, putative 0.0044 0.0018 0.0018
Entamoeba histolytica ankyrin repeat protein 0.0046 0.0039 0.0048
Brugia malayi Immunoglobulin I-set domain containing protein 0.0096 0.0565 0.0597
Loa Loa (eye worm) hypothetical protein 0.0187 0.1534 0.1648
Loa Loa (eye worm) TK/EPH protein kinase 0.0125 0.0876 0.0935
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0747 0.3127
Loa Loa (eye worm) hypothetical protein 0.0113 0.0747 0.0796
Onchocerca volvulus 0.0187 0.1534 0.2926
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0081 0.0414 0.0496
Onchocerca volvulus 0.0101 0.0627 0.1195
Schistosoma mansoni protein kinase 0.0046 0.0039 0.0046
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Loa Loa (eye worm) STAT protein 0.0055 0.0136 0.0134
Echinococcus granulosus activated cdc42 kinase 1 0.0046 0.0039 0.0036
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0115 0.0769 0.0765
Schistosoma mansoni tyrosine kinase 0.0076 0.0361 0.0663
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0505 0.2008
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0048 0.0062 0.0058
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0509 0.088
Echinococcus granulosus SH2 motif 0.0055 0.0136 0.0133
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0072 0.031 0.0322
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0109 0.0162
Brugia malayi Sex muscle abnormal protein 5 0.0095 0.0558 0.0589
Leishmania major protein kinase, putative 0.0152 0.1164 0.4902
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Entamoeba histolytica hypothetical protein 0.0044 0.0018 0.001
Onchocerca volvulus 0.0108 0.0695 0.1325
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Leishmania major protein kinase, putative 0.0131 0.0946 0.3972
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1494 0.2835
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0055 0.0136 0.0212
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0129 0.0127
Schistosoma mansoni protein kinase 0.0046 0.0039 0.0046
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0675 0.0671
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0039 0.0038
Brugia malayi ephrin receptor 1 precursor 0.0075 0.0349 0.0363
Echinococcus multilocularis integrin alpha 3 0.0115 0.0769 0.0924
Leishmania major protein kinase A catalytic subunit isoform 2 0.0113 0.0747 0.3127
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Brugia malayi Immunoglobulin I-set domain containing protein 0.0613 0.6063 0.6552
Plasmodium vivax hexose transporter 0.0106 0.0675 0.1415
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.122 0.5142
Toxoplasma gondii NEK kinase 0.0053 0.0109 0.0308
Schistosoma mansoni tyrosine kinase 0.0252 0.2228 0.4245
Trichomonas vaginalis STE family protein kinase 0.0085 0.0457 0.0786
Echinococcus granulosus casein kinase I alpha 0.0109 0.0703 0.0699
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0157 0.122 0.5142
Plasmodium vivax unspecified product 0.01 0.0615 0.1287
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Giardia lamblia Kinase, CMGC DYRK 0.0138 0.1014 0.4198
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0081 0.0404 0.0746
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0807 0.1518
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0046 0.0039 0.0036
Onchocerca volvulus 0.0055 0.0136 0.026
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0969 0.1165
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0509 0.0947
Brugia malayi Cam kinase protein 1 0.0131 0.0946 0.1009
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0149 0.0256
Trichomonas vaginalis AGC family protein kinase 0.0294 0.267 0.4756
Brugia malayi Protein kinase domain containing protein 0.0437 0.4188 0.4521
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.008 0.0398 0.0476
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0358 0.3349 0.3613
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.1014 0.1785
Echinococcus multilocularis expressed conserved protein 0.0134 0.0969 0.1165
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.011 0.0716 0.0762
Plasmodium falciparum protein kinase 5 0.0118 0.0807 0.1698
Echinococcus granulosus insulin receptor 0.0389 0.3683 0.3681
Giardia lamblia Kinase, CDC7 0.009 0.0509 0.2024
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.01 0.0615 0.1287
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Entamoeba histolytica protein kinase , putative 0.0144 0.108 0.1913
Echinococcus multilocularis serine:threonine protein kinase N2 0.0291 0.264 0.3183
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0199 0.1666 0.2007
Echinococcus granulosus nervana 2 0.0119 0.0817 0.0814
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0226 0.195 0.2349
Onchocerca volvulus Serine\/threonine kinase homolog 0.0162 0.1271 0.2425
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Plasmodium falciparum tyrosine kinase-like protein 0.0046 0.0039 0.0054
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0344 0.3204 0.6111
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0067 0.0262 0.0312
Echinococcus granulosus tyrosine protein kinase pr2 0.0046 0.0039 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Loa Loa (eye worm) hypothetical protein 0.0108 0.0695 0.0739
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Entamoeba histolytica protein kinase, putative 0.0084 0.0441 0.0767
Loa Loa (eye worm) hypothetical protein 0.0445 0.428 0.4622
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0884 0.1553
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0044 0.0018 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Onchocerca volvulus 0.0055 0.0136 0.026
Brugia malayi casein kinase I 0.0109 0.0703 0.0746
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Loa Loa (eye worm) SH2 domain-containing protein 0.0055 0.0136 0.0134
Trypanosoma cruzi protein kinase, putative 0.0046 0.0039 0.0108
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0344 0.3204 0.3456
Echinococcus granulosus cyclin dependent kinase 7 0.011 0.0716 0.0712
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0085 0.0447 0.1631
Loa Loa (eye worm) hypothetical protein 0.0083 0.0429 0.0451
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Echinococcus multilocularis thioredoxin glutathione reductase 0.0044 0.002 0.002
Giardia lamblia Kinase, PLK 0.0265 0.236 1
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0231 0.1998 0.1995
Leishmania major serine/threonine-protein kinase, putative 0.0053 0.0109 0.0404
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.1014 0.1785
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Echinococcus multilocularis CDC7 cell division cycle 7 0.009 0.0509 0.061
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Leishmania major protein kinase, putative 0.0046 0.0039 0.0108
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0072 0.0315 0.0376
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0152 0.1164 0.4902
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0044 0.0018 0.0016
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0046 0.0042 0.0054
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Giardia lamblia Aurora kinase 0.0144 0.108 0.4486
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0131 0.0946 0.0942
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.0946 0.1137
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0769 0.1346
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0807 0.0969
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0055 0.0136 0.0133
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0807 0.1518
Schistosoma mansoni suppressor of cytokine signaling 0.0055 0.0136 0.0232
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0138 0.1014 0.1084
Brugia malayi hypothetical protein 0.0054 0.0128 0.0123
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Entamoeba histolytica hypothetical protein 0.0046 0.0042 0.0054
Schistosoma mansoni hypothetical protein 0.0055 0.0136 0.0232
Giardia lamblia Kinase, NEK 0.0053 0.0109 0.0299
Plasmodium falciparum mitogen-activated protein kinase 2 0.0205 0.1724 0.3663
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus granulosus tyrosine kinase 0.0101 0.0627 0.0623
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0259 0.2298 0.277
Loa Loa (eye worm) hypothetical protein 0.0108 0.0695 0.0739
Echinococcus granulosus tyrosine protein kinase 0.0278 0.2498 0.2495
Brugia malayi SH2 domain containing protein 0.0055 0.0136 0.0133
Echinococcus multilocularis serine threonine protein kinase 0.0205 0.173 0.2084
Schistosoma mansoni vesicular amine transporter 0.0081 0.0404 0.0746
Echinococcus granulosus nervana 2 0.0119 0.0817 0.0814
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0615 0.107
Loa Loa (eye worm) hypothetical protein 0.0058 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0139 0.1021 0.1092
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0046 0.0039 0.0083
Mycobacterium tuberculosis Putative ferredoxin reductase 0.01 0.061 0.8342
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0046 0.0039 0.0029
Schistosoma mansoni nephrin 0.0054 0.012 0.02
Trypanosoma brucei Flagellum attachment zone protein 20 0.0046 0.0039 0.0096
Loa Loa (eye worm) sugar transporter 0.0106 0.0675 0.0717
Onchocerca volvulus Tyrosine kinase homolog 0.0536 0.5242 1
Plasmodium falciparum protein serine/threonine kinase-1 0.0152 0.1164 0.2463
Onchocerca volvulus 0.0282 0.2545 0.4854
Loa Loa (eye worm) hypothetical protein 0.0101 0.0627 0.0665
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0132 0.0946 0.3034
Loa Loa (eye worm) hypothetical protein 0.0096 0.0565 0.0598
Brugia malayi TAR-binding protein 0.0073 0.0328 0.034
Echinococcus granulosus calcium activated potassium channel 0.0134 0.0971 0.0968
Loa Loa (eye worm) glutathione reductase 0.0044 0.0014 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trypanosoma brucei rac serine-threonine kinase, putative 0.0294 0.267 1
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Leishmania major serine/threonine-protein kinase a, putative 0.0044 0.0018 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.1803 0.3429
Trichomonas vaginalis AGC family protein kinase 0.0144 0.108 0.1905
Echinococcus multilocularis tyrosine protein kinase pr2 0.0046 0.0039 0.0043
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Entamoeba histolytica protein kinase, putative 0.0227 0.1963 0.3495
Schistosoma mansoni tyrosine kinase 0.0314 0.2881 0.5496
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0569 0.5594 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0046 0.0039 0.0027
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0048 0.0062 0.0089
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.01 0.061 0.8342
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni protein kinase 0.0066 0.0248 0.0447
Schistosoma mansoni neuroglian 0.0054 0.012 0.02
Loa Loa (eye worm) TK/FER protein kinase 0.0394 0.3737 0.4034
Entamoeba histolytica PH domain containing protein kinase, putative 0.0044 0.0018 0.001
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0344 0.3204 0.3201
Loa Loa (eye worm) SH2 domain-containing protein 0.0055 0.0136 0.0134
Echinococcus granulosus growth factor receptor bound protein 2 0.0097 0.0578 0.0575
Schistosoma mansoni titin 0.0072 0.031 0.0564
Plasmodium falciparum casein kinase 1 0.0109 0.0703 0.1475
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0138 0.1014 0.4261
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.1164 0.2203
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0703 0.0748
Schistosoma mansoni adapter molecule crk 0.0095 0.0558 0.104
Schistosoma mansoni vav2 0.0104 0.0657 0.123
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0747 0.0898
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Loa Loa (eye worm) hypothetical protein 0.0081 0.0407 0.0428
Schistosoma mansoni tyrosine kinase 0.0226 0.195 0.371
Brugia malayi tRNA modification GTPase TrmE family protein 0.0055 0.0136 0.0133
Loa Loa (eye worm) hypothetical protein 0.0054 0.0128 0.0125
Echinococcus multilocularis casein kinase i 0.0109 0.0703 0.0844
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0046 0.0039 0.0029
Echinococcus multilocularis tyrosine protein kinase HCK 0.0131 0.0941 0.1132
Schistosoma mansoni serine/threonine protein kinase 0.0344 0.3204 0.6115
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0087 0.047 0.0564
Schistosoma mansoni tyrosine kinase 0.0535 0.5229 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0226 0.195 0.1947
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0054 0.012 0.0116
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Brugia malayi Protein kinase domain containing protein 0.0101 0.0627 0.0664
Schistosoma mansoni rap gtpase-activating protein 0.0108 0.0695 0.1303
Trypanosoma cruzi polo-like protein kinase, putative 0.0265 0.236 1
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0046 0.0039 0.0027
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0039 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.1014 0.1785
Echinococcus multilocularis SH2 motif 0.0055 0.0136 0.016
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0119 0.0817 0.0982
Loa Loa (eye worm) casein kinase 0.0174 0.1397 0.15
Loa Loa (eye worm) TK/INSR protein kinase 0.0389 0.3683 0.3975
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0056 0.0149 0.0148
Giardia lamblia Kinase, CMGC GSK 0.0227 0.1963 0.8291
Echinococcus multilocularis tyrosine protein kinase shark 0.0308 0.2816 0.3395
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0447 0.0828
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Onchocerca volvulus 0.0044 0.0012 0.0024
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0747 0.0795
Plasmodium vivax calcium-dependent protein kinase, putative 0.0132 0.0946 0.1996
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0131 0.0946 0.1009
Schistosoma mansoni ephrin receptor 0.0108 0.0696 0.1305
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0384 0.363 0.3628
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.236 0.4199
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0046 0.0039 0.0036
Onchocerca volvulus 0.0046 0.0039 0.0075
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0807 0.086
Loa Loa (eye worm) TK/ROR protein kinase 0.0067 0.0262 0.027
Echinococcus granulosus ephrin type A receptor 4 A 0.0108 0.0696 0.0692
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0583 0.574 0.6203
Echinococcus granulosus cGMP dependent protein kinase 0.0134 0.0969 0.0965
Entamoeba histolytica protein kinase, putative 0.0131 0.0946 0.1672
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0155 0.1195 0.2528
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0226 0.195 0.2349
Echinococcus multilocularis N chimaerin 0.0096 0.0565 0.0678
Onchocerca volvulus 0.0046 0.0039 0.0075
Brugia malayi Variant SH3 domain containing protein 0.0095 0.0558 0.0589
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0095 0.0558 0.059
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Echinococcus granulosus tyrosine protein kinase Blk 0.0186 0.1528 0.1525
Echinococcus multilocularis myotubularin protein 13 0.0049 0.0069 0.0079
Echinococcus granulosus tyrosine protein kinase ABL1 0.0302 0.2753 0.275
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Schistosoma mansoni cell adhesion molecule 0.0054 0.012 0.02
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0055 0.0136 0.0212
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0232 0.2011 0.2423
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.01 0.061 0.8342
Echinococcus multilocularis SH2 domain containing protein 7 0.0055 0.0136 0.016
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0085 0.0447 0.1847
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0039 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.2298 0.4379
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Echinococcus multilocularis tyrosine protein kinase Srms 0.0186 0.1528 0.1841
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Entamoeba histolytica SH2 domain containing protein 0.0055 0.0136 0.0222
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0807 0.1414
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0747 0.1404
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.031 0.0564
Echinococcus multilocularis 0.0123 0.0854 0.1026
Schistosoma mansoni tensin 0.0055 0.0136 0.0232
Brugia malayi Tyrosine-protein kinase PR2 0.0046 0.0039 0.0027
Loa Loa (eye worm) hypothetical protein 0.0079 0.0384 0.0403
Echinococcus granulosus casein kinase I delta 0.0109 0.0703 0.0699
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0109 0.0703 0.2936
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.008 0.0398 0.0476
Trypanosoma cruzi casein kinase, putative 0.0109 0.0703 0.2936
Loa Loa (eye worm) hypothetical protein 0.0108 0.0695 0.0739
Brugia malayi hypothetical protein 0.0047 0.0044 0.0033
Loa Loa (eye worm) hypothetical protein 0.0174 0.1401 0.1504
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.1803 0.3429
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0118 0.0807 0.338
Brugia malayi Protein kinase domain containing protein 0.0162 0.1271 0.1362
Brugia malayi SH2 domain containing protein 0.0055 0.0136 0.0133
Loa Loa (eye worm) hypothetical protein 0.0201 0.1683 0.181
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0457 0.1887
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0152 0.1164 0.1247
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0118 0.0807 0.338
Echinococcus multilocularis receptor type guanylyl cyclase 0.0046 0.0039 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0101 0.0627 0.0665
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni cell adhesion molecule 0.0054 0.012 0.02
Brugia malayi Kelch motif family protein 0.0047 0.0044 0.0033
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0226 0.195 0.2349
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni signal transduction protein lnk-related 0.0055 0.0136 0.0232
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0039 0.0043
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0157 0.122 0.1308
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0807 0.338
Toxoplasma gondii protein kinase domain-containing protein 0.0046 0.0039 0.0083
Echinococcus granulosus cyclin dependent kinase 5 0.0118 0.0807 0.0803
Echinococcus multilocularis 0.0055 0.0136 0.016
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0969 0.0965
Entamoeba histolytica protein kinase, putative 0.0066 0.0248 0.0422
Schistosoma mansoni protein kinase 0.0046 0.0039 0.0046
Echinococcus granulosus tyrosine kinase 0.0186 0.1528 0.1525
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0044 0.0018 0.0018
Brugia malayi Guanylyl cyclase protein 23 0.0046 0.0039 0.0027
Plasmodium vivax tyrosine kinase-like protein, putative 0.0082 0.0419 0.0868
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Loa Loa (eye worm) hypothetical protein 0.0114 0.0759 0.0808
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0039 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.1014 0.1915
Brugia malayi SH2 domain containing protein 0.0055 0.0136 0.0133
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0328 0.0599
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0055 0.0136 0.016
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Plasmodium falciparum NIMA related kinase 2 0.0053 0.0109 0.0203
Echinococcus multilocularis casein kinase I gamma 0.021 0.1775 0.2138
Echinococcus multilocularis transfer RNA-Thr 0.0046 0.0039 0.0043
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0033 0.0021
Echinococcus multilocularis calcium activated potassium channel 0.0134 0.0971 0.1168
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0162 0.1268 0.136
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0675 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0197 0.1647 0.177
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Echinococcus multilocularis c src tyrosine kinase 0.0141 0.1048 0.1261
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0044 0.0018 0.0018
Toxoplasma gondii casein kinase I 0.0109 0.0703 0.2242
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0053 0.0109 0.0203
Onchocerca volvulus 0.0046 0.0039 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0294 0.267 0.4756
Echinococcus granulosus hypothetical protein 0.0116 0.0786 0.0783
Schistosoma mansoni hypothetical protein 0.0046 0.0039 0.0046
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0125 0.0881 0.3695
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Onchocerca volvulus 0.0046 0.0039 0.0075
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0039 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0205 0.1724 0.3663
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0046 0.0039 0.0027
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0162 0.1271 0.1268
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0046 0.0039 0.0038
Loa Loa (eye worm) TK/FER protein kinase 0.0101 0.0627 0.0665
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0056 0.0149 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Brugia malayi RNA binding protein 0.0073 0.0328 0.034
Echinococcus granulosus expressed protein 0.0084 0.0441 0.0437
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Entamoeba histolytica protein kinase domain containing protein 0.01 0.0615 0.108
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0113 0.0747 0.2388
Brugia malayi hypothetical protein 0.0055 0.0136 0.0133
Plasmodium vivax tyrosine kinase-like protein, putative 0.0046 0.0039 0.0054
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0046 0.0039 0.0048
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0039 0.0043
Echinococcus granulosus tyrosine protein kinase shark 0.0308 0.2816 0.2813
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0481 0.4657 0.4656
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0399 0.3783 0.3781
Entamoeba histolytica protein kinase, putative 0.0072 0.0315 0.0542
Loa Loa (eye worm) hypothetical protein 0.0119 0.0815 0.0869
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0144 0.108 0.13
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0072 0.0315 0.0311
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.1963 0.3488
Leishmania major folate/biopterin transporter, putative 0.0044 0.0018 0.0018
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0085 0.0447 0.1847
Brugia malayi Protein kinase domain containing protein 0.0482 0.467 0.5043
Schistosoma mansoni integrin beta subunit 0.0181 0.1469 0.2788
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0055 0.0136 0.016
Schistosoma mansoni protein kinase 0.0046 0.0039 0.0046
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0096 0.0565 0.0562
Loa Loa (eye worm) hypothetical protein 0.0116 0.0786 0.0838
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0695 0.1303
Onchocerca volvulus 0.0046 0.0039 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0583 0.574 0.6203
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Echinococcus granulosus casein kinase I gamma 0.021 0.1775 0.1772
Brugia malayi cyclin-dependent kinase 7 homolog 0.011 0.0716 0.076
Brugia malayi Pleckstrin Homology Domain 0.0049 0.0069 0.006
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0119 0.0817 0.0814
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0358 0.3349 0.3347
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.122 0.5142
Brugia malayi Tyrosine-protein kinase abl-1 0.0124 0.0862 0.0919
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0807 0.338
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0081 0.0404 0.0484
Trypanosoma cruzi polo-like protein kinase, putative 0.0265 0.236 1
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0039 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0946 0.1664
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0155 0.1195 0.1438
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0152 0.1164 0.4902
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0703 0.0844
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0108 0.0695 0.0834
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.009 0.0505 0.1052
Echinococcus granulosus tyrosine protein kinase HCK 0.0131 0.0941 0.0938
Schistosoma mansoni tyrosine kinase 0.0238 0.2072 0.3945
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Plasmodium vivax protein kinase, putative 0.0061 0.0194 0.0386
Echinococcus multilocularis serine:threonine protein kinase 3 0.0252 0.2222 0.2678
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0183 0.1494 0.1604
Schistosoma mansoni protein kinase 0.0046 0.0039 0.0046
Echinococcus granulosus tyrosine protein kinase Fyn 0.0226 0.195 0.1947
Echinococcus granulosus casein kinase I delta 0.0109 0.0703 0.0699
Echinococcus granulosus tyrosine protein kinase csk 0.0046 0.0039 0.0036
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0186 0.1528 0.1841
Echinococcus granulosus dual specificity 0.0138 0.1014 0.101
Echinococcus granulosus netrin receptor unc 5 0.0046 0.0033 0.0029
Echinococcus multilocularis dual specificity 0.0138 0.1014 0.1219
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0044 0.0018 0.0018
Echinococcus multilocularis tyrosine protein kinase Abl 0.0218 0.1861 0.2242
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0207 0.1752 0.1884
Brugia malayi SH2 domain containing protein 0.0394 0.3737 0.4033
Echinococcus granulosus neuroglian 0.0101 0.0627 0.0623
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0424 0.0446
Plasmodium falciparum protein kinase, putative 0.0082 0.0417 0.0863
Brugia malayi Integrin alpha pat-2 precursor 0.015 0.1141 0.122
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0046 0.0039 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.1647 0.313
Entamoeba histolytica protein kinase domain containing protein 0.0122 0.0842 0.1486
Echinococcus granulosus tar DNA binding protein 0.0073 0.0328 0.0324
Onchocerca volvulus 0.0101 0.0627 0.1195
Trichomonas vaginalis AGC family protein kinase 0.0294 0.267 0.4756
Brugia malayi SH2 domain containing protein 0.0055 0.0136 0.0133
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus granulosus mitogen activated protein kinase 0.0085 0.0447 0.0444
Echinococcus granulosus General substrate transporter 0.0091 0.0517 0.0513
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0759 0.0911
Plasmodium vivax casein kinase 1, putative 0.0109 0.0703 0.1475
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0218 0.1867 0.1864
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0072 0.0315 0.0376
Brugia malayi serine/threonine protein kinase 6 0.0144 0.108 0.1155
Loa Loa (eye worm) TK/FER protein kinase 0.0101 0.0627 0.0665
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0227 0.1963 0.831
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0703 0.0844
Entamoeba histolytica PH domain containing protein kinase, putative 0.0044 0.0018 0.001
Trypanosoma cruzi NIMA-related kinase, putative 0.0044 0.0018 0.0018
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0747 0.0898
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni ephrin receptor 0.0061 0.02 0.0354
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0039 0.0029
Plasmodium falciparum hexose transporter 0.0106 0.0675 0.1415
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0093 0.0134
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0695 0.2902
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0039 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0328 0.0599
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0053 0.0109 0.0404
Schistosoma mansoni nephrin 0.0117 0.0787 0.1481
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0453 0.4361 0.526
Echinococcus granulosus signal transduction protein lnk realted 0.0055 0.0136 0.0133
Loa Loa (eye worm) TK/FER protein kinase 0.0101 0.0627 0.0665
Echinococcus granulosus cyclin dependent kinase 0.0118 0.0807 0.0803
Entamoeba histolytica hypothetical protein 0.0046 0.0039 0.0048
Echinococcus multilocularis serine:threonine protein kinase 38 0.0166 0.131 0.1578
Echinococcus multilocularis dual specificity 0.0122 0.0842 0.1012
Trichomonas vaginalis STE family protein kinase 0.0066 0.0248 0.0412
Entamoeba histolytica protein kinase, putative 0.0144 0.108 0.1913
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0759 0.0755
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0065 0.0241 0.0247
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.131 0.2484
Entamoeba histolytica PH domain containing protein kinase, putative 0.0164 0.1286 0.2282
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0144 0.108 0.1077
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0062 0.021 0.0206
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0053 0.0109 0.0404
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Brugia malayi hypothetical protein 0.0046 0.0039 0.0027
Echinococcus granulosus roundabout 2 0.0054 0.012 0.0116
Brugia malayi Protein kinase domain containing protein 0.021 0.1775 0.1907
Loa Loa (eye worm) hypothetical protein 0.0119 0.0815 0.0869
Leishmania major protein kinase, putative 0.0053 0.0109 0.0404
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0747 0.0744
Echinococcus multilocularis integrin beta 2 0.0227 0.1964 0.2367
Loa Loa (eye worm) hypothetical protein 0.0113 0.0753 0.0802
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0082 0.0417 0.1312
Schistosoma mansoni lipoxygenase 0.0083 0.0426 0.0788
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.122 0.1469
Echinococcus granulosus titin 0.0072 0.031 0.0306
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0143 0.1072 0.129
Brugia malayi protein unc-22 0.0072 0.031 0.032
Plasmodium falciparum calcium-dependent protein kinase 1 0.0132 0.0946 0.1996
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Echinococcus multilocularis natriuretic peptide receptor 1 0.0046 0.0039 0.0043
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0807 0.1423
Brugia malayi p70 ribosomal S6 kinase beta 0.0285 0.2578 0.2778
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0615 0.107
Echinococcus multilocularis dual specificity 0.0138 0.1014 0.1219
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0075 0.0346 0.0361
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0039 0.0048
Entamoeba histolytica protein kinase, putative 0.0133 0.0959 0.1695
Echinococcus multilocularis tensin 0.0055 0.0136 0.016
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0122 0.0842 0.3117
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.1963 0.3488
Echinococcus multilocularis mitogen activated protein kinase 3 0.0085 0.0447 0.0535
Trypanosoma brucei Casein kinase II 0.01 0.0615 0.2263
Loa Loa (eye worm) TK protein kinase 0.0046 0.0039 0.0029
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0232 0.2011 0.2008
Echinococcus multilocularis epidermal growth factor receptor 0.0448 0.4304 0.5191
Brugia malayi Receptor family ligand binding region containing protein 0.0046 0.0039 0.0027
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0695 0.2563
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Brugia malayi Protein kinase c protein 2 0.0115 0.0775 0.0824
Loa Loa (eye worm) TK/Met protein kinase 0.0046 0.0039 0.0029
Loa Loa (eye worm) hypothetical protein 0.03 0.2733 0.2947
Echinococcus multilocularis protein tyrosine kinase 0.0535 0.5229 0.6308
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0111 0.0728 1
Trypanosoma brucei cdc2-related kinase 3 0.0118 0.0807 0.2985
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0046 0.0039 0.0046
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0747 0.0744
Schistosoma mansoni kinase 0.0282 0.2549 0.486
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0039 0.0048
Giardia lamblia Kinase, CMGC SRPK 0.0084 0.0441 0.173
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.01 0.0615 0.0653
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0315 0.0575
Plasmodium falciparum cGMP-dependent protein kinase 0.0134 0.0969 0.2045
Echinococcus multilocularis serine:threonine protein kinase N2 0.0166 0.131 0.1578
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Loa Loa (eye worm) serine/threonine protein kinase 0.0046 0.0039 0.0029
Giardia lamblia Kinase, STE STE20 0.0087 0.047 0.1858
Brugia malayi hypothetical protein 0.0096 0.0565 0.0597
Brugia malayi hypothetical protein 0.0046 0.0039 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0615 0.107
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0056 0.0149 0.0148
Plasmodium falciparum calcium-dependent protein kinase 4 0.0132 0.0946 0.1996
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0913 0.9247 1
Brugia malayi Protein kinase domain containing protein 0.0197 0.1647 0.1769
Echinococcus granulosus defective proboscis extension response 0.0081 0.0404 0.0401
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0807 0.3307
Schistosoma mansoni serine/threonine protein kinase 0.025 0.2203 0.4197
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0747 0.0796
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0144 0.108 0.1913
Echinococcus multilocularis netrin receptor unc 5 0.0046 0.0033 0.0035
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0055 0.0136 0.016
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0039 0.0029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0226 0.195 0.2349
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0122 0.0842 0.353
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0056 0.0149 0.0575
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Brugia malayi putative serine/threonine kinase SADA gamma 0.009 0.0505 0.0532
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.236 0.4199
Trichomonas vaginalis TK family protein kinase 0.0046 0.0039 0.0038
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0747 0.1571
Brugia malayi Egg laying defective protein 4 0.0134 0.0969 0.1034
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni serine/threonine RGC 0.0046 0.0039 0.0046
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0166 0.131 0.1578
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0072 0.0315 0.0311
Echinococcus granulosus NCK adaptor protein 0.0095 0.0558 0.0554
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0971 0.1833
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni GTPase activating protein 0.0055 0.0136 0.0232
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0218 0.1867 0.2249
Echinococcus granulosus fch and double sh3 domains protein 2 0.0044 0.0012 0.0009
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0046 0.0039 0.0036
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0111 0.0728 1
Schistosoma mansoni protein kinase 0.0109 0.0703 0.1318
Echinococcus multilocularis protein kinase 0.0046 0.0039 0.0043
Echinococcus granulosus titin 0.0072 0.031 0.0306
Onchocerca volvulus 0.0077 0.0369 0.0703
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.0675 0.081
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus multilocularis raf serine:threonine protein kinase 0.0087 0.0468 0.0561
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0164 0.1286 0.5424
Entamoeba histolytica PH domain containing protein kinase, putative 0.0121 0.0839 0.1481
Echinococcus multilocularis integrin alpha ps 0.0067 0.0262 0.0312
Loa Loa (eye worm) protein kinase domain-containing protein 0.021 0.1775 0.1909
Plasmodium falciparum protein kinase 6 0.0483 0.4683 1
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Onchocerca volvulus 0.009 0.0509 0.0971
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0199 0.1666 0.179
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0096 0.0565 0.1054
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0675 0.0671
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0055 0.0136 0.0133
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0247 0.2173 0.2619
Brugia malayi Cytochrome P450 family protein 0.0055 0.0129 0.0125
Loa Loa (eye worm) AUR protein kinase 0.0144 0.108 0.1156
Entamoeba histolytica protein kinase domain containing protein 0.0227 0.1963 0.3495
Trichomonas vaginalis AGC family protein kinase 0.0294 0.267 0.4756
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0205 0.1724 0.5568
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0447 0.0769
Echinococcus granulosus calcium dependent protein kinase 0.0096 0.0568 0.0565
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0087 0.047 0.0564
Trypanosoma brucei protein kinase, putative 0.0044 0.0018 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0294 0.267 0.4756
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0457 0.1887
Trypanosoma brucei SNF1-related protein kinases, putative 0.009 0.0505 0.185
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Leishmania major casein kinase, putative 0.0109 0.0703 0.2936
Entamoeba histolytica protein kinase 2, putative 0.0155 0.1195 0.2118
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0138 0.1014 0.1083
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0394 0.3737 0.4507
Trichomonas vaginalis CMGC family protein kinase 0.0152 0.1164 0.2055
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0224 0.1927 0.1924
Entamoeba histolytica casein kinase, putative 0.0109 0.0703 0.1237
Trypanosoma cruzi casein kinase II, putative 0.01 0.0615 0.2563
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0039 0.0046
Entamoeba histolytica hypothetical protein 0.0046 0.0039 0.0048
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0807 0.0969
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0082 0.0419 0.0868
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0082 0.0424 0.0507
Schistosoma mansoni protein kinase C mu 0.0214 0.182 0.3461
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0226 0.195 0.2349
Brugia malayi protein kinase C3,putative 0.0156 0.1205 0.1291
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0592 0.5843 0.5841
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0152 0.1164 0.3743
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0118 0.0803 0.0965
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0113 0.0747 0.1571
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0183 0.1494 0.1799
Brugia malayi Protein kinase domain containing protein 0.0166 0.131 0.1404
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.236 0.4199
Echinococcus granulosus Vam6:Vps39 protein 0.0108 0.0695 0.0691
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0048 0.006 0.0068
Echinococcus granulosus tyrosine protein kinase Src64B 0.0226 0.195 0.1947
Brugia malayi Protein kinase domain containing protein 0.0583 0.574 0.6203
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0044 0.0018 0.0016
Brugia malayi Protein kinase domain containing protein 0.0274 0.2465 0.2655
Onchocerca volvulus 0.0046 0.0039 0.0075
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.01 0.061 0.8342
Brugia malayi serine/threonine-protein kinase plk-2 0.0265 0.236 0.2541
Schistosoma mansoni tyrosine kinase 0.0361 0.3382 0.6458
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0152 0.1164 0.4329
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0055 0.0136 0.0212
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0055 0.0136 0.016
Echinococcus multilocularis cyclin dependent kinase 5 0.0118 0.0807 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.264 0.5034
Schistosoma mansoni hypothetical protein 0.0098 0.0594 0.1109
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0197 0.1647 0.1983
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0759 0.0911
Schistosoma mansoni tyrosine kinase 0.0246 0.2166 0.4125
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0703 0.1228
Schistosoma mansoni protein kinase 0.0232 0.2011 0.3828
Echinococcus granulosus serine:threonine protein kinase 3 0.0252 0.2222 0.2219
Schistosoma mansoni serine/threonine kinase 0.0166 0.131 0.2484
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0117 0.0789 0.0839
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0046 0.0039 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.009 0.0505 0.0534
Brugia malayi Protein kinase domain containing protein 0.0186 0.152 0.1631
Echinococcus granulosus suppressor of cytokine signaling 6 0.0055 0.0136 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.131 0.2484
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Schistosoma mansoni vam6/vps39 related 0.0108 0.0695 0.1303
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0509 0.088
Brugia malayi Protein kinase domain containing protein 0.0118 0.0807 0.0859
Loa Loa (eye worm) TK protein kinase 0.0131 0.0941 0.1006
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.0675 0.0671
Brugia malayi C-terminal src kinase protein 1 0.0046 0.0039 0.0027
Giardia lamblia Kinase, NEK 0.0135 0.0984 0.4073
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0782 0.1471
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0087 0.047 0.0564
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0055 0.0136 0.0232
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.1014 0.1785
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.1867 0.3552
Loa Loa (eye worm) hypothetical protein 0.0098 0.0592 0.0628
Brugia malayi Protein kinase domain containing protein 0.0114 0.0759 0.0807
Schistosoma mansoni tyrosine protein kinase 0.0046 0.0039 0.0046
Schistosoma mansoni tyrosine kinase 0.0389 0.3683 0.7035
Echinococcus multilocularis cyclin dependent kinase 0.0118 0.0807 0.0969
Echinococcus granulosus integrin linked protein kinase 0.0046 0.0039 0.0036
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0695 0.1303
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0046 0.0039 0.0036
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0138 0.1014 0.4261
Brugia malayi Kinase associated domain 1 family protein 0.0098 0.0594 0.0628
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0115 0.0769 0.0923
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.015 0.1143 0.2016
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Echinococcus multilocularis neuroglian 0.0101 0.0627 0.0752
Echinococcus multilocularis SH2 motif 0.0055 0.0136 0.016
Schistosoma mansoni protein kinase 0.0453 0.4361 0.8335
Onchocerca volvulus 0.0101 0.0627 0.1195
Echinococcus multilocularis growth factor receptor bound protein 2 0.0095 0.0558 0.0669
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0695 0.2902
Loa Loa (eye worm) hypothetical protein 0.0348 0.3247 0.3503
Schistosoma mansoni protein kinase 0.0046 0.0039 0.0046
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0328 0.0341
Schistosoma mansoni tyrosine kinase 0.0314 0.2881 0.5496
Entamoeba histolytica protein kinase, putative 0.0044 0.0018 0.001
Entamoeba histolytica tyrosin kinase, putative 0.0049 0.0072 0.0107
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0046 0.0039 0.0038
Brugia malayi Doublecortin family protein 0.0149 0.1135 0.1214
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0082 0.0424 0.042
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0226 0.195 0.2349
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0039 0.0036
Entamoeba histolytica casein kinase 1, putative 0.0109 0.0703 0.1237
Leishmania major protein kinase, putative 0.0044 0.0018 0.0018
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0481 0.4657 0.5618
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0424 0.0728
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.1014 0.1785
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Loa Loa (eye worm) TK protein kinase 0.0046 0.0039 0.0029
Schistosoma mansoni protein kinase 0.0046 0.0039 0.0046
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0055 0.0136 0.016
Brugia malayi probable protein kinase 0.0259 0.2305 0.2481
Loa Loa (eye worm) hypothetical protein 0.0098 0.0594 0.0629
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0087 0.047 0.0467
Brugia malayi Protein kinase domain containing protein 0.0084 0.0441 0.0462
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Schistosoma mansoni suppressor of cytokine signaling 0.0055 0.0136 0.0232
Echinococcus granulosus N chimaerin 0.0096 0.0565 0.0562
Loa Loa (eye worm) TK/FER protein kinase 0.0101 0.0627 0.0665
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0969 0.0965
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0039 0.0048
Echinococcus granulosus dual specificity 0.0138 0.1014 0.101
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0065 0.0055
Trypanosoma brucei NIMA-related protein kinase 0.0053 0.0109 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.021 0.1775 0.3375
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0039 0.0046
Entamoeba histolytica protein kinase, putative 0.0122 0.0842 0.1486
Echinococcus granulosus epidermal growth factor receptor 0.0448 0.4304 0.4302
Loa Loa (eye worm) hypothetical protein 0.0138 0.1013 0.1084
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Echinococcus granulosus tyrosine protein kinase Lyn 0.0262 0.2327 0.2324
Loa Loa (eye worm) TK/FER protein kinase 0.0101 0.0627 0.0665
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0131 0.0946 0.0942
Loa Loa (eye worm) TK/FER protein kinase 0.0101 0.0627 0.0665
Loa Loa (eye worm) AUR protein kinase 0.0144 0.108 0.1156
Brugia malayi C1-like domain containing protein 0.0214 0.182 0.1956
Loa Loa (eye worm) IKK protein kinase 0.0482 0.467 0.5044
Schistosoma mansoni tyrosine kinase 0.0141 0.1048 0.1981
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0085 0.0447 0.1847
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0109 0.0162
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Giardia lamblia Kinase, CMGC GSK 0.0227 0.1963 0.8291
Echinococcus multilocularis protein kinase c iota type 0.0286 0.2589 0.3121
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0101 0.0627 0.11
Loa Loa (eye worm) TK/FAK protein kinase 0.054 0.5291 0.5716
Loa Loa (eye worm) hypothetical protein 0.0064 0.0228 0.0233
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0183 0.1494 0.1603
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0162 0.016
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0046 0.0039 0.0046
Brugia malayi Protein kinase domain containing protein 0.0185 0.1511 0.1622
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0096 0.0565 0.1054
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0055 0.0136 0.026
Brugia malayi Protein kinase domain containing protein 0.0082 0.0424 0.0444
Schistosoma mansoni tyrosine kinase 0.0267 0.239 0.4556
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0214 0.182 0.1956
Echinococcus granulosus protein kinase 0.0046 0.0039 0.0036
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0747 0.0898
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus multilocularis titin 0.0072 0.031 0.0369
Loa Loa (eye worm) hypothetical protein 0.0096 0.0565 0.0598
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Echinococcus multilocularis 0.0152 0.1159 0.1394
Schistosoma mansoni protein kinase 0.019 0.1566 0.2973
Schistosoma mansoni protein kinase 0.0152 0.1159 0.2193
Schistosoma mansoni integrin alpha 0.015 0.1141 0.2158
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0155 0.1195 0.5033
Giardia lamblia Kinase, CK1 Casein kinase 0.0109 0.0703 0.2859
Brugia malayi hypothetical protein 0.0108 0.0695 0.0737
Loa Loa (eye worm) hypothetical protein 0.0123 0.0852 0.091
Trypanosoma cruzi aurora B kinase, putative 0.0144 0.108 0.4546
Plasmodium vivax glycogen synthase kinase 3, putative 0.0227 0.1963 0.4175
Loa Loa (eye worm) hypothetical protein 0.009 0.0505 0.0534
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.2922 0.5576
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0096 0.0565 0.0678
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Leishmania major protein kinase, putative 0.0152 0.1164 0.4902
Schistosoma mansoni lipoxygenase 0.0118 0.0803 0.1512
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0747 0.0744
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0109 0.0703 0.0748
Echinococcus multilocularis PAK box P21 Rho binding 0.0066 0.0248 0.0295
Schistosoma mansoni tensin-related 0.0055 0.0136 0.0232
Brugia malayi Immunoglobulin I-set domain containing protein 0.0054 0.012 0.0115
Schistosoma mansoni protein kinase 0.0087 0.047 0.0873
Onchocerca volvulus 0.0101 0.0627 0.1195
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Brugia malayi integrin-linked kinase 0.0046 0.0039 0.0027
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Echinococcus granulosus mitogen activated protein kinase 3 0.0085 0.0447 0.0444
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Brugia malayi Variant SH3 domain containing protein 0.0065 0.0241 0.0246
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0447 0.0769
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus granulosus serine:threonine protein kinase N2 0.0291 0.264 0.2637
Echinococcus multilocularis tyrosine kinase 0.0101 0.0627 0.0752
Echinococcus granulosus Immunoglobulin 0.0081 0.0404 0.0401
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0054 0.012 0.014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Brugia malayi Sugar transporter family protein 0.0106 0.0675 0.0716
Schistosoma mansoni glucose transport protein 0.0106 0.0675 0.1265
Loa Loa (eye worm) TK protein kinase 0.0339 0.315 0.3398
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0569 0.5594 1
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.2159 0.4111
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0077 0.037 0.0366
Echinococcus granulosus kinase suppressor of Ras 1 0.0046 0.0039 0.0036
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Entamoeba histolytica protein kinase, putative 0.0046 0.0042 0.0054
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0441 0.1819
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0328 0.0341
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0152 0.1164 0.4902
Brugia malayi serine/threonine-protein kinase PAK 7 0.0228 0.1968 0.2117
Schistosoma mansoni protein kinase 0.0046 0.0039 0.0046
Onchocerca volvulus 0.0178 0.1442 0.2751
Schistosoma mansoni tyrosine kinase 0.0267 0.239 0.4556
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0404 0.3844 0.3841
Toxoplasma gondii protein kinase domain-containing protein 0.0044 0.0018 0.0014
Toxoplasma gondii aurora kinase 0.0144 0.108 0.3471
Echinococcus granulosus aurora kinase A 0.0144 0.108 0.1077
Brugia malayi Protein kinase domain containing protein 0.0344 0.3204 0.3455
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0228 0.1968 0.2118
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0152 0.1164 0.4329
Trichomonas vaginalis AGC family protein kinase 0.0294 0.267 0.4756
Echinococcus granulosus tyrosine kinase 0.0046 0.0039 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0424 0.0728
Loa Loa (eye worm) hypothetical protein 0.0134 0.0972 0.1039
Mycobacterium ulcerans hypothetical protein 0.0098 0.0591 0.5
Onchocerca volvulus 0.0055 0.0136 0.026
Trichomonas vaginalis STE family protein kinase 0.0087 0.047 0.0811
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0946 0.1785
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.008 0.0398 0.0733
Loa Loa (eye worm) hypothetical protein 0.0231 0.2007 0.216
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0447 0.0769
Entamoeba histolytica cysteine surface protein, putative 0.0046 0.0039 0.0048
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0044 0.0018 0.0018
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0218 0.1867 0.2008
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0131 0.0946 0.3508
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Entamoeba histolytica hypothetical protein 0.0046 0.0039 0.0048
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0302 0.2753 0.3319
Echinococcus multilocularis dual specificity protein kinase clk2 0.0152 0.1164 0.1401
Loa Loa (eye worm) TK protein kinase 0.0046 0.0039 0.0029
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0132 0.0946 0.1996
Echinococcus granulosus NDR protein kinase 0.0166 0.131 0.1307
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0085 0.0447 0.1847
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Entamoeba histolytica hypothetical protein 0.0044 0.0018 0.001
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0417 0.1517
Trichomonas vaginalis AGC family protein kinase 0.0166 0.131 0.2318
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0971 0.1833
Loa Loa (eye worm) hypothetical protein 0.0062 0.0205 0.0209
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0085 0.0447 0.141
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0053 0.0109 0.0203
Schistosoma mansoni tensin-related 0.0055 0.0136 0.0232
Schistosoma mansoni netrin receptor unc5 0.0046 0.0033 0.0034
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0246 0.2159 0.2602
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.1666 0.3166
Plasmodium falciparum glycogen synthase kinase 3 0.0227 0.1963 0.4175
Giardia lamblia Kinase, CMGC CLK 0.0152 0.1164 0.4846
Echinococcus granulosus expressed conserved protein 0.0055 0.0136 0.0133
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0149 0.0256
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0703 0.0844
Echinococcus granulosus SHC transforming protein 3 0.0055 0.0136 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0081 0.0414 0.0765
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0085 0.0447 0.1847
Echinococcus multilocularis Immunoglobulin 0.0081 0.0404 0.0484
Echinococcus granulosus myotubularin protein 13 0.0049 0.0069 0.0066
Mycobacterium tuberculosis Probable dehydrogenase 0.01 0.061 0.8342
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0085 0.0447 0.0471
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0106 0.0675 0.081
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Brugia malayi P38 map kinase family protein 2 0.0157 0.122 0.1306
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0227 0.1963 0.2113
Loa Loa (eye worm) TK/ABL protein kinase 0.0302 0.2753 0.2968
Echinococcus granulosus tyrosine protein kinase Fyn 0.0226 0.195 0.1947
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0073 0.0325 0.1327
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0417 0.1718
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0131 0.0946 0.0942
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0085 0.0457 0.1667
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0747 0.1404
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0046 0.0039 0.0046
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Brugia malayi Tyrosine-protein kinase abl-1 0.0218 0.1861 0.2001
Schistosoma mansoni protein kinase 0.0082 0.0417 0.077
Entamoeba histolytica protein kinase, putative 0.0138 0.1014 0.1794
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0328 0.0599
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0085 0.0457 0.0796
Schistosoma mansoni protein kinase 0.0453 0.4361 0.8335
Echinococcus granulosus Protein kinase C brain isozyme 0.0246 0.2159 0.2156
Entamoeba histolytica p21-activated kinase 0.0095 0.0562 0.0985
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0186 0.1528 0.1525
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0328 0.0599
Echinococcus multilocularis mitogen activated protein kinase 0.0085 0.0447 0.0535
Trypanosoma brucei protein kinase, putative 0.0227 0.1963 0.7339
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0314 0.2881 0.2878
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0046 0.0039 0.0046
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0118 0.0807 0.0803
Schistosoma mansoni tyrosine kinase 0.0389 0.3683 0.7035
Leishmania major protein kinase, putative 0.0082 0.0417 0.1718
Echinococcus multilocularis Immunoglobulin 0.0081 0.0404 0.0484
Echinococcus multilocularis casein kinase I delta 0.0109 0.0703 0.0844
Brugia malayi MAP kinase sur-1 0.0085 0.0447 0.0469
Echinococcus granulosus activated cdc42 kinase 1 0.0046 0.0039 0.0036
Echinococcus granulosus integrin beta 2 0.0227 0.1964 0.1961
Echinococcus granulosus protein kinase c epsilon type 0.0207 0.1752 0.1749
Entamoeba histolytica protein kinase, putative 0.0074 0.034 0.0587
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Trichomonas vaginalis protein tyrosine kinase, putative 0.0046 0.0039 0.0038
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0081 0.0404 0.0746
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0118 0.0807 0.086
Schistosoma mansoni protein kinase 0.0087 0.047 0.0873
Onchocerca volvulus 0.0055 0.0136 0.026
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.108 0.2043
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0227 0.1963 0.6346
Brugia malayi STAT protein, DNA binding domain containing protein 0.0055 0.0136 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0049 0.0069 0.0062
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0186 0.152 0.1633
Entamoeba histolytica hypothetical protein 0.0046 0.0042 0.0054
Entamoeba histolytica hypothetical protein 0.0048 0.0062 0.0089
Plasmodium falciparum protein kinase 7 0.0333 0.3086 0.6579
Echinococcus multilocularis insulin receptor 0.0389 0.3683 0.4442
Schistosoma mansoni growth factor receptor-bound protein 0.0095 0.0558 0.104
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Plasmodium vivax serine/threonine kinase-1, putative 0.0152 0.1164 0.2463
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0039 0.0048
Trypanosoma cruzi SNF1-related protein kinases, putative 0.009 0.0505 0.2095
Toxoplasma gondii CMGC kinase, CK2 family 0.01 0.0615 0.1957
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Schistosoma mansoni tensin 0.0055 0.0136 0.0232
Onchocerca volvulus Netrin receptor homolog 0.0049 0.0068 0.013
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0321 0.2964 0.3197
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0807 0.338
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0344 0.3204 0.3456
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0098 0.0592 0.0588
Schistosoma mansoni protein kinase 0.01 0.0615 0.115
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.009 0.0505 0.2095
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0747 0.1308
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.2159 0.4111
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0077 0.037 0.0442
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0096 0.0565 0.0598
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0044 0.0018 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0109 0.0162
Entamoeba histolytica protein kinase, putative 0.0072 0.0315 0.0542
Giardia lamblia Kinase, NEK 0.0135 0.0984 0.4073
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0152 0.1164 0.4902
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0046 0.0039 0.0027
Entamoeba histolytica serine/threonine protein kinase, putative 0.0265 0.236 0.4205
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0046 0.0039 0.0027
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0144 0.108 0.2284
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Entamoeba histolytica hypothetical protein 0.0046 0.0039 0.0048
Loa Loa (eye worm) AGC/PKG protein kinase 0.0134 0.0969 0.1036
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Plasmodium falciparum NIMA related kinase 4 0.0053 0.0109 0.0203
Entamoeba histolytica protein kinase, putative 0.0074 0.034 0.0587
Trypanosoma cruzi protein kinase, putative 0.0046 0.0039 0.0108
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0505 0.2008
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Toxoplasma gondii NEK kinase 0.0053 0.0109 0.0308
Entamoeba histolytica protein kinase domain containing protein 0.0227 0.1963 0.3495
Trypanosoma brucei Pseudokinase, putative 0.0046 0.0039 0.0096
Plasmodium falciparum calcium-dependent protein kinase 5 0.0132 0.0946 0.1996
Entamoeba histolytica hypothetical protein 0.0367 0.3446 0.6151
Loa Loa (eye worm) TK/ACK protein kinase 0.0046 0.0039 0.0029
Onchocerca volvulus Serine\/threonine kinase homolog 0.0265 0.236 0.4501
Echinococcus multilocularis tensin 0.0055 0.0136 0.016
Loa Loa (eye worm) CDC7 protein kinase 0.009 0.0509 0.0538
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0091 0.0514 0.0898
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Echinococcus granulosus protein kinase shaggy 0.0227 0.1963 0.196
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0321 0.2964 0.3195
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0328 0.0391
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0065 0.0057
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0384 0.363 0.3918
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0252 0.2222 0.2393
Schistosoma mansoni tyrosine kinase 0.0308 0.2816 0.5371
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0394 0.3737 0.3735
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Loa Loa (eye worm) hypothetical protein 0.0583 0.574 0.6203
Loa Loa (eye worm) AUR protein kinase 0.0144 0.108 0.1156
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0055 0.0136 0.0134
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0132 0.0946 0.3034
Leishmania major protein kinase, putative 0.0144 0.108 0.4546
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Onchocerca volvulus 0.0046 0.0039 0.0075
Brugia malayi Furin-like cysteine rich region family protein 0.0448 0.4304 0.4646
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0199 0.1666 0.1663
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0084 0.0441 0.1389
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Toxoplasma gondii protein kinase, putative 0.0333 0.3086 1
Echinococcus multilocularis integrin linked protein kinase 0.0046 0.0039 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0328 0.0599
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0747 0.2762
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0039 0.0043
Brugia malayi Immunoglobulin I-set domain containing protein 0.0054 0.012 0.0115
Loa Loa (eye worm) TK protein kinase 0.0046 0.0039 0.0029
Plasmodium falciparum calcium-dependent protein kinase 7 0.0044 0.0018 0.0009
Plasmodium falciparum calcium-dependent protein kinase 2 0.0132 0.0946 0.1996
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0064 0.0228 0.0376
Schistosoma mansoni glucose transport protein 0.0106 0.0675 0.1265
Echinococcus multilocularis kinase suppressor of Ras 1 0.0046 0.0039 0.0043
Loa Loa (eye worm) hypothetical protein 0.0118 0.0799 0.0851
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Schistosoma mansoni hypothetical protein 0.0106 0.0675 0.1265
Toxoplasma gondii STE kinase 0.0046 0.0039 0.0083
Echinococcus granulosus SH2 motif 0.0055 0.0136 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0716 0.1344
Loa Loa (eye worm) TK/ALK protein kinase 0.0274 0.2464 0.2655
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Onchocerca volvulus 0.0134 0.0972 0.1854
Brugia malayi Protein kinase domain containing protein 0.019 0.1566 0.1681
Onchocerca volvulus 0.0055 0.0136 0.026
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0226 0.195 0.2349
Loa Loa (eye worm) hypothetical protein 0.0348 0.3247 0.3503
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0162 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0759 0.1328
Loa Loa (eye worm) hypothetical protein 0.0178 0.1442 0.1548
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0258 0.2295 0.247
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0417 0.1718
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0747 0.2762
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0842 0.1585
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0337 0.313 0.3376
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Loa Loa (eye worm) TK/FER protein kinase 0.0101 0.0627 0.0665
Loa Loa (eye worm) hypothetical protein 0.0086 0.0464 0.0489
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0227 0.1963 0.196
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0039 0.0029
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0238 0.2072 0.2497
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.108 0.1913
Brugia malayi Fes/CIP4 homology domain containing protein 0.0113 0.0748 0.0796
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Brugia malayi protein-tyrosine kinase 0.0186 0.1528 0.164
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0087 0.047 0.0467
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Brugia malayi Protein kinase domain containing protein 0.0294 0.267 0.2877
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0424 0.0784
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0081 0.0414 0.0411
Schistosoma mansoni tyrosine kinase 0.0141 0.1048 0.1981
Echinococcus granulosus c src tyrosine kinase 0.0141 0.1048 0.1045
Loa Loa (eye worm) hypothetical protein 0.0083 0.0427 0.0449
Entamoeba histolytica protein kinase, putative 0.0122 0.0842 0.1486
Echinococcus multilocularis Glutaredoxin protein 5 0.012 0.0823 0.0989
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trypanosoma cruzi Protein kinase B 0.0164 0.1286 0.5424
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0769 0.1346
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0247 0.2173 0.217
Plasmodium falciparum serine/threonine protein kinase 0.0084 0.0441 0.0914
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0807 0.3307
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0067 0.0262 0.0258
Leishmania major protein kinase, putative 0.0085 0.0457 0.1887
Brugia malayi Protein kinase domain containing protein 0.0101 0.0627 0.0664
Brugia malayi Serine/threonine-protein kinase SULU 0.0218 0.1867 0.2007
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0047 0.0044 0.0035
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Trichomonas vaginalis protein kinase atn1, putative 0.0046 0.0039 0.0038
Plasmodium vivax CDK-related protein kinase 6, putative 0.0483 0.4683 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0132 0.0946 0.1996
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0226 0.195 0.1947
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0131 0.0946 0.1137
Brugia malayi bone morphogenetic protein type 1 receptor 0.0046 0.0039 0.0027
Echinococcus granulosus dual specificity 0.0122 0.0842 0.0839
Echinococcus multilocularis FL cytokine receptor 0.0046 0.0039 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0384 0.363 0.6934
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0109 0.0179
Echinococcus granulosus protein kinase C gamma type 0.0205 0.173 0.1727
Echinococcus multilocularis activin receptor type 0.0082 0.0417 0.0499
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Loa Loa (eye worm) RNA binding protein 0.0073 0.0328 0.0341
Loa Loa (eye worm) TK/RYK protein kinase 0.0046 0.0039 0.0029
Schistosoma mansoni tyrosine kinase 0.0267 0.239 0.4556
Trypanosoma brucei protein kinase, putative 0.0082 0.0417 0.1517
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Brugia malayi cell division control protein 2 homolog 0.0118 0.0807 0.0859
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0114 0.0759 0.0808
Loa Loa (eye worm) integrin alpha pat-2 0.0231 0.2002 0.2155
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Brugia malayi Protein kinase domain containing protein 0.0122 0.0842 0.0897
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0118 0.0803 0.08
Echinococcus granulosus protein tyrosine kinase 0.0535 0.5229 0.5227
Brugia malayi Temporarily assigned gene name protein 59 0.0125 0.0872 0.0929
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0053 0.0109 0.0404
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0096 0.0565 0.0599
Loa Loa (eye worm) TK protein kinase 0.0046 0.0039 0.0029
Brugia malayi Protein kinase domain containing protein 0.009 0.0509 0.0536
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.1271 0.2408
Mycobacterium tuberculosis Probable oxidoreductase 0.0111 0.0728 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0039 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.2173 0.4138
Echinococcus granulosus tyrosine protein kinase Fyn 0.0226 0.195 0.1947
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Echinococcus multilocularis dual specificity 0.0138 0.1014 0.1219
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0131 0.0946 0.1011
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Brugia malayi Protein kinase domain containing protein 0.0101 0.0627 0.0664
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0044 0.0012 0.001
Entamoeba histolytica protein kinase, putative 0.0044 0.0018 0.001
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0087 0.047 0.0467
Echinococcus multilocularis nervana 2 0.0119 0.0817 0.0982
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0039 0.0048
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0166 0.131 0.1307
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0807 0.338
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0971 0.1833
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0135 0.0984 0.3159
Plasmodium falciparum serine/threonine protein kinase KIN 0.009 0.0505 0.1052
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0716 0.1344
Trichomonas vaginalis AGC family protein kinase 0.0186 0.152 0.2694
Schistosoma mansoni serine/threonine-protein kinase 0.0164 0.1286 0.2438
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Brugia malayi hypothetical protein 0.0101 0.0627 0.0664
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0144 0.108 0.1913
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.009 0.0505 0.2095
Onchocerca volvulus 0.0138 0.1013 0.1933
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0142 0.1059 0.1274
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0039 0.0038
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0046 0.0039 0.0075
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0046 0.0039 0.0038
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0122 0.0842 0.0898
Brugia malayi Integrin beta pat-3 precursor 0.0307 0.2809 0.3027
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.122 0.1469
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0675 0.1178
Echinococcus granulosus receptor type guanylyl cyclase 0.0046 0.0039 0.0036
Brugia malayi SH2 domain containing protein 0.0055 0.0136 0.0133
Echinococcus granulosus protein kinase c iota type 0.0286 0.2589 0.2587
Schistosoma mansoni cell adhesion molecule 0.0113 0.0753 0.1414
Echinococcus multilocularis activated cdc42 kinase 1 0.0046 0.0039 0.0043
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0265 0.236 0.2542
Brugia malayi Protein kinase domain containing protein 0.0101 0.0627 0.0664
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0238 0.2072 0.2497
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0135 0.0984 0.2079
Brugia malayi Protein kinase domain containing protein 0.0101 0.0627 0.0664
Echinococcus granulosus epidermal growth factor receptor 0.0314 0.2881 0.2878
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0173 0.1391 0.1493
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0969 0.1828
Loa Loa (eye worm) hypothetical protein 0.0131 0.0946 0.1011
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0399 0.3783 0.4563
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Plasmodium vivax serine/threonine protein kinase, putative 0.0084 0.0441 0.0914
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0259 0.2298 0.2475
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0044 0.0018 0.0018
Echinococcus granulosus cyclin dependent kinase 1 0.0118 0.0807 0.0803
Echinococcus multilocularis casein kinase I delta 0.0109 0.0703 0.0844
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0118 0.0807 0.2581
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0039 0.0038
Plasmodium falciparum protein kinase, putative 0.0046 0.0039 0.0054
Echinococcus granulosus roundabout 2 0.0134 0.0975 0.0972
Trichomonas vaginalis STE family protein kinase 0.0135 0.0984 0.1733
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0747 0.0796
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0046 0.0039 0.0036
Onchocerca volvulus 0.0073 0.0325 0.062
Echinococcus granulosus tyrosine protein kinase Src42A 0.0226 0.195 0.1947
Giardia lamblia Kinase, AGC AKT 0.0117 0.0789 0.3231
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.236 0.4497
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1998 0.3803
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0328 0.034
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0424 0.0446
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0141 0.1048 0.1981
Loa Loa (eye worm) hypothetical protein 0.0115 0.0769 0.0819
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0747 0.1404
Echinococcus granulosus casein kinase ii subunit alpha 0.01 0.0615 0.0612
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0505 0.094
Entamoeba histolytica protein kinase, putative 0.0294 0.267 0.4762
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.1164 0.2203
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Entamoeba histolytica casein kinase, putative 0.01 0.0615 0.108
Entamoeba histolytica protein kinase, putative 0.0082 0.0424 0.0737
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0081 0.0414 0.0434
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Plasmodium vivax tyrosine kinase-like protein, putative 0.0046 0.0039 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0039 0.0038
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.019 0.1566 0.1682
Echinococcus granulosus SH2 domain containing adapter protein F 0.0055 0.0136 0.0133
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0144 0.108 0.1913
Brugia malayi Temporarily assigned gene name protein 59 0.0108 0.0695 0.0737
Brugia malayi RhoGAP domain containing protein 0.0096 0.0565 0.0597
Brugia malayi Casein kinase II, alpha chain 0.01 0.0615 0.0651
Brugia malayi SH2 domain containing protein 0.0101 0.0627 0.0664
Trichomonas vaginalis STE family protein kinase 0.0046 0.0039 0.0038
Trypanosoma cruzi NIMA-related kinase, putative 0.0044 0.0018 0.0018
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0039 0.0043
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Schistosoma mansoni hypothetical protein 0.0098 0.0594 0.1109
Echinococcus multilocularis NCK adaptor protein 0.0097 0.0578 0.0693
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0046 0.0039 0.0029
Echinococcus multilocularis death associated protein kinase 1 0.0823 0.8287 1
Brugia malayi Tensin 0.0055 0.0136 0.0133
Onchocerca volvulus 0.0101 0.0627 0.1195
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0039 0.0048
Schistosoma mansoni serine/threonine-protein kinase 0.0164 0.1292 0.245
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0615 0.107
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0437 0.4188 0.4522
Echinococcus multilocularis nervana 2 0.0119 0.0817 0.0982
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0046 0.0039 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0294 0.267 0.4756
Echinococcus granulosus tyrosine protein kinase Src42A 0.0142 0.1059 0.1055
Onchocerca volvulus 0.0318 0.2922 0.5574
Entamoeba histolytica hypothetical protein 0.0046 0.0039 0.0048
Brugia malayi hypothetical protein 0.0218 0.1867 0.2007
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0285 0.2578 0.2779
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0046 0.0039 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0615 0.107
Echinococcus granulosus neuroglian 0.0054 0.012 0.0116
Echinococcus multilocularis heat shock protein 70 0.0046 0.0039 0.0043
Brugia malayi serine/threonine-protein kinase 6 0.0144 0.108 0.1155
Loa Loa (eye worm) hypothetical protein 0.0086 0.0464 0.0489
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0072 0.0107
Loa Loa (eye worm) AGC/NDR protein kinase 0.0166 0.131 0.1406
Echinococcus granulosus mitogen activated protein kinase 14 0.0157 0.122 0.1217
Schistosoma mansoni nck2/grb4 0.0095 0.0558 0.104
Entamoeba histolytica serine/threonine protein kinase, putative 0.0053 0.0109 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Schistosoma mansoni tyrosine kinase 0.0085 0.0449 0.0833
Plasmodium falciparum serine/threonine protein kinase, putative 0.0144 0.108 0.2284
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0231 0.1998 0.2408
Loa Loa (eye worm) TK/DDR protein kinase 0.0046 0.0039 0.0029
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0212 0.1803 0.18
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0134 0.0969 0.3108
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0155 0.1195 0.1191
Trypanosoma brucei aurora B kinase 0.0144 0.108 0.4015
Echinococcus granulosus c-Jun N-terminal kinases 0.0259 0.2298 0.2295
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0046 0.0039 0.0046
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0095 0.0558 0.104
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0131 0.0946 0.1011
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0441 0.0816
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.236 0.4199
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0053 0.0109 0.0404
Loa Loa (eye worm) TK protein kinase 0.0278 0.2498 0.2691
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.1014 0.1794
Schistosoma mansoni hypothetical protein 0.0108 0.0695 0.1303
Brugia malayi Immunoglobulin I-set domain containing protein 0.0072 0.031 0.032
Echinococcus granulosus tyrosine protein kinase csk 0.0046 0.0039 0.0036
Trypanosoma brucei polo-like protein kinase 0.0265 0.236 0.8832
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0046 0.0039 0.0027
Echinococcus multilocularis SHC transforming protein 3 0.0055 0.0136 0.016
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.1014 0.1785
Schistosoma mansoni growth factor receptor-bound protein 0.0097 0.0578 0.1079
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0703 0.1228
Trypanosoma cruzi NIMA-related kinase, putative 0.0053 0.0109 0.0404
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Echinococcus granulosus raf serine:threonine protein kinase 0.0087 0.0468 0.0465
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0747 0.3127
Onchocerca volvulus 0.0101 0.0627 0.1195
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0703 0.0748
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0046 0.0039 0.0029
Brugia malayi Raf kinase 0.0046 0.0039 0.0027
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0095 0.0558 0.059
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0505 0.094
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0447 0.0769
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.122 0.1469
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0138 0.1014 0.3254
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0046 0.0039 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Echinococcus multilocularis myosin iiia 0.0085 0.0457 0.0547
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.008 0.0398 0.0476
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Giardia lamblia Kinase, AGC PKA 0.0113 0.0747 0.3052
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0212 0.1803 0.2173
Trichomonas vaginalis AGC family protein kinase 0.0186 0.152 0.2694
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0048 0.0062 0.007
Schistosoma mansoni serine/threonine kinase 0.0213 0.1813 0.3449
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus granulosus casein kinase i 0.0109 0.0703 0.0699
Onchocerca volvulus 0.009 0.0509 0.0971
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0143 0.1072 0.1069
Loa Loa (eye worm) hypothetical protein 0.0081 0.0404 0.0424
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0044 0.0018 0.0018
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0039 0.0048
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0969 0.1165
Plasmodium falciparum calcium-dependent protein kinase 3 0.0132 0.0946 0.1996
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0505 0.2095
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0053 0.0109 0.0357
Echinococcus granulosus natriuretic peptide receptor 1 0.0046 0.0039 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0265 0.236 0.2844
Mycobacterium tuberculosis Probable reductase 0.01 0.061 0.8342
Brugia malayi SH2 domain containing protein 0.0055 0.0136 0.0133
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0807 0.1414
Loa Loa (eye worm) SH2 domain-containing protein 0.0055 0.0136 0.0134
Entamoeba histolytica protein kinase, putative 0.0131 0.0941 0.1664
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Echinococcus multilocularis epidermal growth factor receptor 0.0314 0.2881 0.3473
Schistosoma mansoni protein kinase 0.0259 0.2305 0.4391
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Giardia lamblia Kinase, CMGC MAPK 0.0085 0.0447 0.1758
Brugia malayi SRC-1 0.0226 0.195 0.2097
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0227 0.1963 0.2113
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0039 0.0029
Schistosoma mansoni protein kinase 0.0144 0.108 0.2043
Echinococcus multilocularis tyrosine protein kinase 0.0278 0.2498 0.3011
Trypanosoma cruzi casein kinase, putative 0.0109 0.0703 0.2936
Entamoeba histolytica protein kinase, putative 0.0285 0.2578 0.4597
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0441 0.1607
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0212 0.1803 0.18
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0046 0.0039 0.0075
Brugia malayi casein kinase 1, delta 0.0109 0.0703 0.0746
Entamoeba histolytica protein kinase, putative 0.0294 0.267 0.4762
Entamoeba histolytica protein kinase, putative 0.0084 0.0441 0.0767
Echinococcus multilocularis hypothetical protein 0.0098 0.0594 0.0712
Plasmodium falciparum NIMA related kinase 1 0.0135 0.0984 0.2079
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Brugia malayi Protein kinase domain containing protein 0.054 0.5291 0.5715
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0453 0.4361 0.4359
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Echinococcus granulosus protein kinase 0.0152 0.1159 0.1156
Plasmodium falciparum casein kinase 2, alpha subunit 0.01 0.0615 0.1287
Entamoeba histolytica PH domain containing protein kinase, putative 0.0121 0.0839 0.1481
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0087
Echinococcus multilocularis rac serine:threonine kinase 0.0164 0.1286 0.1548
Brugia malayi Protein kinase domain containing protein 0.0191 0.1575 0.1691
Onchocerca volvulus 0.0046 0.0039 0.0075
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0358 0.3349 0.4039
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0044 0.0018 0.0014
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.0675 0.081
Echinococcus granulosus serine:threonine protein kinase N2 0.0125 0.0878 0.0875
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0212 0.1803 0.2173
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0162 0.1271 0.1363
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0085 0.0457 0.0796
Schistosoma mansoni serine/threonine protein kinase 0.0207 0.1752 0.3332
Echinococcus granulosus casein kinase I alpha 0.0109 0.0703 0.0699
Brugia malayi Immunoglobulin I-set domain containing protein 0.0054 0.012 0.0115
Loa Loa (eye worm) hypothetical protein 0.0081 0.0404 0.0424
Brugia malayi Variant SH3 domain containing protein 0.0095 0.0558 0.0589
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0213 0.1813 0.195
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0344 0.3204 0.3455
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0404 0.3844 0.4636
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0111 0.0728 1
Loa Loa (eye worm) integrin beta-2 0.0307 0.2809 0.3029
Loa Loa (eye worm) CAMK protein kinase 0.0072 0.031 0.0322
Brugia malayi Protein kinase domain containing protein 0.0358 0.3349 0.3612
Schistosoma mansoni hypothetical protein 0.0055 0.0136 0.0232
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0747 0.3127
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0265 0.236 0.2357
Trypanosoma cruzi p21-activated kinase 3, putative 0.0056 0.0149 0.0575
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0046 0.0039 0.0096
Echinococcus multilocularis protein kinase 0.0046 0.0039 0.0043
Echinococcus multilocularis roundabout 2 0.0134 0.0975 0.1173
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0807 0.1423
Trypanosoma cruzi casein kinase, putative 0.0109 0.0703 0.2936
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0029
Onchocerca volvulus 0.0469 0.4529 0.864
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0046 0.0039 0.0083
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0228 0.0376
Loa Loa (eye worm) hypothetical protein 0.0055 0.0136 0.0134
Trichomonas vaginalis STE family protein kinase 0.0087 0.047 0.0811
Entamoeba histolytica ankyrin repeat protein 0.0046 0.0039 0.0048
Onchocerca volvulus 0.0227 0.1963 0.3745
Leishmania major casein kinase II, putative 0.01 0.0615 0.2563
Trichomonas vaginalis STE family protein kinase 0.0087 0.047 0.0811
Entamoeba histolytica protein kinase, putative 0.0166 0.131 0.2326
Plasmodium vivax protein kinase Crk2 0.0118 0.0807 0.1698
Schistosoma mansoni tyrosine kinase 0.0046 0.0039 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0468 0.0868
Brugia malayi SH2 domain containing protein 0.0055 0.0136 0.0133
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0044 0.0018 0.0018
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0227 0.1963 0.2366
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0505 0.0873
Brugia malayi Protein kinase domain containing protein 0.0913 0.9247 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.0505 0.0883
Echinococcus multilocularis cyclin dependent kinase 7 0.011 0.0716 0.086
Echinococcus multilocularis General substrate transporter 0.0091 0.0517 0.0619
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0046 0.0039 0.0043
Leishmania major protein kinase A catalytic subunit isoform 1 0.0113 0.0747 0.3127
Toxoplasma gondii NEK kinase 0.0053 0.0109 0.0308
Loa Loa (eye worm) hypothetical protein 0.0224 0.1927 0.2073
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0046 0.0039 0.0048
Echinococcus multilocularis neuroglian 0.0054 0.012 0.014
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0039 0.0048
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0152 0.1159 0.1242
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0265 0.236 1
Onchocerca volvulus 0.0109 0.0703 0.134
Brugia malayi Protein kinase domain containing protein 0.0213 0.1813 0.1949
Trichomonas vaginalis STE family protein kinase 0.0053 0.0109 0.0162
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0047 0.0044 0.0035
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0044 0.0018 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus multilocularis serine:threonine protein kinase N2 0.0125 0.0878 0.1056
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0136 0.0212
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.236 0.4199
Onchocerca volvulus 0.0055 0.0136 0.026
Entamoeba histolytica protein kinase domain containing protein 0.0199 0.1666 0.2963
Echinococcus granulosus roundabout 2 0.0054 0.012 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0149 0.0256
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0085 0.0447 0.1847
Trichomonas vaginalis AGC family protein kinase 0.0135 0.0984 0.1733
Loa Loa (eye worm) AGC/AKT protein kinase 0.0294 0.267 0.2878
Schistosoma mansoni protein tyrosine kinase 0.0046 0.0039 0.0046
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0615 0.107
Echinococcus multilocularis signal transduction protein lnk realted 0.0055 0.0136 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0039 0.0038
Echinococcus granulosus CDC7 cell division cycle 7 0.009 0.0509 0.0505
Echinococcus granulosus twitchin 0.0137 0.1004 0.1001
Echinococcus multilocularis tyrosine kinase 0.0046 0.0039 0.0043
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0226 0.195 0.2349
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0048 0.006 0.0056
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0132 0.0946 0.1996
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0039 0.0029
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0108 0.0695 0.0691
Schistosoma mansoni tyrosine kinase 0.0448 0.4304 0.8226
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0884 0.1553
Brugia malayi Protein kinase domain 0.0087 0.047 0.0495
Echinococcus granulosus dual specificity 0.0138 0.1014 0.101
Loa Loa (eye worm) TK protein kinase 0.0258 0.2295 0.2472
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0089 0.0497 0.0525
Entamoeba histolytica protein kinase, putative 0.0046 0.0039 0.0048
Echinococcus granulosus integrin alpha ps 0.0067 0.0262 0.0259
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0046 0.0039 0.0046
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0214 0.182 0.1957
Loa Loa (eye worm) hypothetical protein 0.0054 0.012 0.0116
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0079 0.0389 0.0408
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0155 0.1195 0.2528
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0197 0.1647 0.1644
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0132 0.0946 0.3034
Echinococcus granulosus serine:threonine kinase SAD 1 0.009 0.0505 0.0502
Echinococcus multilocularis protein KINase family member (kin 25) 0.0046 0.0039 0.0043
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus granulosus activin receptor type 0.0082 0.0417 0.0413
Echinococcus multilocularis calcium dependent protein kinase 0.0096 0.0568 0.0682
Loa Loa (eye worm) SRC-1 0.0226 0.195 0.2098
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0247 0.2173 0.234
Echinococcus granulosus serine threonine protein kinase nrc 0.0155 0.1195 0.1191
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0703 0.1228
Echinococcus multilocularis twitchin 0.0056 0.0149 0.0175
Echinococcus granulosus tyrosine protein kinase csk 0.0046 0.0039 0.0036
Entamoeba histolytica hypothetical protein 0.0046 0.0039 0.0048
Schistosoma mansoni integrin alpha-ps 0.0067 0.0262 0.0474
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0039 0.0048
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0039 0.0048
Loa Loa (eye worm) hypothetical protein 0.0134 0.0972 0.1039
Schistosoma mansoni protein kinase 0.0358 0.3349 0.6394
Brugia malayi cytokine inducible SH2-containing protein 5 0.0055 0.0136 0.0133
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0199 0.1666 0.1791
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0157 0.122 0.4541
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0027
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0344 0.3204 0.3863
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0807 0.086
Onchocerca volvulus 0.0046 0.0039 0.0075
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Echinococcus multilocularis 0.0116 0.0786 0.0945
Entamoeba histolytica hypothetical protein 0.0122 0.0842 0.1486
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0144 0.1074 0.1292
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0039 0.0048
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0759 0.0755
Schistosoma mansoni serine/threonine protein kinase 0.0464 0.4479 0.8562
Brugia malayi serine/threonine kinase 12 0.0144 0.108 0.1155
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0842 0.353
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0039 0.0038
Giardia lamblia Kinase, CMGC CK2 0.01 0.0615 0.2481
Toxoplasma gondii AGC kinase 0.0113 0.0747 0.2388
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0505 0.094
Loa Loa (eye worm) hypothetical protein 0.0054 0.0128 0.0125
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0166 0.131 0.1307
Echinococcus granulosus suppressor of cytokine signaling 7 0.0055 0.0136 0.0133
Schistosoma mansoni tyrosine kinase 0.0226 0.195 0.371
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0166 0.131 0.1578
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0226 0.195 0.2349
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0807 0.1414
Brugia malayi Stress-activated protein kinase jnk-1 0.0259 0.2298 0.2474
Giardia lamblia Kinase, STE STE20 0.0085 0.0457 0.1798
Leishmania major protein kinase A catalytic subunit 0.0113 0.0747 0.3127
Brugia malayi Protein kinase domain containing protein 0.0583 0.574 0.6203
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0149 0.1135 0.1216

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 15.84893192 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 19.95262315 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) 5.8048 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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